Search

Background:Implanon is a progestin-only implantable contraceptive; it offers promise, long-term, with a high-efficacy contraceptive. It is one of the most effective reversible contraceptives and is of the same effectiveness to sterilization. Objective:To assess the adverse effect profile and effectiveness of subdermal implants. Materials and Methods:A prospective study involved 48 women attending for insertion of the subdermal implant on days 2–5 of their cycle. The implant was inserted subdermally under the effect of local xylocaine of the nondominant arm. Results:The commonest side effect was weight gain constituted 62.5%. At the same time, amenorrhea was reported in 31.3%. Pain at the site of insertion constitutes 14.6%. While bleeding occurred in one case, which responded to local pressure. The commonest cause of discontinuation was weight gain constituted 12.5%. Followed by disturbances in the menstrual cycle. Discontinuation rate 41.7% (20 out of 48 cases). Conclusion:Implanon is an effective long-term contraception with few adverse effects.

Abstract Background Elevated lipids in umbilical cord blood affect fetal programming, leading to a higher risk of developing cardiovascular disease in later life. However, the causes of changes in the lipid profile of umbilical cord blood are not clear yet. This study aimed for the first time to determine the association of asprosin concentration with TAG, TC, HDL-C, LDL-C concentrations and TAG/HDL-C, TC/HDL-C, LDL-C/HDL-C and non-HDL-C/HDL-C ratio in umbilical cord blood as well as newborn anthropometric indices. This cross-sectional study was based on 450 mother- newborn pairs of a birth cohort study in Sabzevar, Iran. Multiple linear regression was used to estimate the association of lipid concentration and lipid ratios as well as birth weight (BW), birth length (BL), head circumference (HC) and chest circumference (CC) with asprosin in cord blood samples controlled for the relevant covariates. Result In fully adjusted models, each 1 ng/mL increase in asprosin was associated with 0.19 (95% CI 0.06, 0.31, P