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348 results on '"Han, Yunfeng"'

5. Molecular Dynamics Study on Mechanical Properties of Calcium–Silicate–Hydrate Considering Model and Parameter Effects

Author

Wang, Xuefeng, Li, Meiyi, Lv, Congcong, Han, Yunfeng, Yin, Hang, Ceccarelli, Marco, Series Editor, Agrawal, Sunil K., Advisory Editor, Corves, Burkhard, Advisory Editor, Glazunov, Victor, Advisory Editor, Hernández, Alfonso, Advisory Editor, Huang, Tian, Advisory Editor, Jauregui Correa, Juan Carlos, Advisory Editor, Takeda, Yukio, Advisory Editor, and Li, Shaofan, editor

Published
2024
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8. DC-Sync: A Doppler-Compensation Time-Synchronization Scheme for Complex Mobile Underwater Sensor Networks

Author

Sun Dajun, Ouyang Yujie, and Han Yunfeng

Subjects
Underwater timing, time synchronization protocol, Doppler estimates, clock skew and offset estimation, Electrical engineering. Electronics. Nuclear engineering, TK1-9971
Abstract

Time synchronization is crucial for effective collaboration among underwater sensors. However, existing synchronization protocols primarily cater to low-speed or simple motion scenarios, neglecting variations in radial velocity during message propagation. A novel Doppler compensation time synchronization scheme, called DC-Sync, was developed in this study to address this issue by targeting complex moving underwater sensors. DC-Sync includes a practical Doppler compensation and estimation method. Simulation results demonstrate that when the target motion follows a specific pattern, DC-Sync outperforms existing similar schemes in terms of time skew and time offset accuracy. Furthermore, the scheme maintains high estimation accuracy even with incomplete Doppler measurement values. Its performance was also validated through physical experiments.

Published
2024
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11. Evaluation of Therapeutic Response to Endocrine Therapy for Prostate Cancer by MRI Diffusion-weighted Imaging Based on PI-RADSv2.1

Author

LI Basen, LIU Liangjin, RUAN Yajun, TAN Fangqin, LI Qin, and HAN Yunfeng

Subjects
prostate cancer, diffusion-weighted imaging, apparent diffusion coefficient, endocrine therapy, prostate-specific antigen, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

Objective To investigate the value of MRI diffusion-weighted imaging (DWI) technique in endocrine therapy for prostate cancer (PCa) based on PI-RADSv2.1. Methods A retrospective analysis of 57 patients with pathologically confirmed PCa was conducted. All patients underwent multi-parametric MRI (mpMRI) according to PI-RADS v2.1 technical specifications before biopsy and six months after endocrine therapy. The apparent diffusion coefficient (ADC) values were measured in cancer and non-cancer areas before biopsy and six months after endocrine therapy. Patients were grouped based on the mRECIST criteria and PSA level into responders (n=45) and non-responders (n=12). ROC curves were obtained to assess the correlation between changes in ADC values and PSA values before and after endocrine therapy. Results In the responder group, the ADC value of the cancer areas was increased significantly after endocrine therapy (P

Published
2023
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16. An Improvement Single Beacon Positioning Algorithm Using Sparse Extended Information Filter for AUV Localization

Author

Zhao, Wanlong, Zhao, Huifeng, Zhang, Jucheng, Han, Yunfeng, Angrisani, Leopoldo, Series Editor, Arteaga, Marco, Series Editor, Panigrahi, Bijaya Ketan, Series Editor, Chakraborty, Samarjit, Series Editor, Chen, Jiming, Series Editor, Chen, Shanben, Series Editor, Chen, Tan Kay, Series Editor, Dillmann, Rüdiger, Series Editor, Duan, Haibin, Series Editor, Ferrari, Gianluigi, Series Editor, Ferre, Manuel, Series Editor, Hirche, Sandra, Series Editor, Jabbari, Faryar, Series Editor, Jia, Limin, Series Editor, Kacprzyk, Janusz, Series Editor, Khamis, Alaa, Series Editor, Kroeger, Torsten, Series Editor, Liang, Qilian, Series Editor, Martín, Ferran, Series Editor, Ming, Tan Cher, Series Editor, Minker, Wolfgang, Series Editor, Misra, Pradeep, Series Editor, Möller, Sebastian, Series Editor, Mukhopadhyay, Subhas, Series Editor, Ning, Cun-Zheng, Series Editor, Nishida, Toyoaki, Series Editor, Pascucci, Federica, Series Editor, Qin, Yong, Series Editor, Seng, Gan Woon, Series Editor, Speidel, Joachim, Series Editor, Veiga, Germano, Series Editor, Wu, Haitao, Series Editor, Zhang, Junjie James, Series Editor, Wang, Wei, editor, Liu, Xin, editor, Na, Zhenyu, editor, Li, Xiaoxia, editor, and Zhang, Baoju, editor

Published
2021
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20. Combustion System Design and Development on 1.4L Miller Gasoline Engine

Author

Wang, Zhanfeng, Liu, Yaodong, Chen, Haie, Huang, Pinghui, Han, Yunfeng, Liu, Ziming, Angrisani, Leopoldo, Series Editor, Arteaga, Marco, Series Editor, Panigrahi, Bijaya Ketan, Series Editor, Chakraborty, Samarjit, Series Editor, Chen, Jiming, Series Editor, Chen, Shanben, Series Editor, Chen, Tan Kay, Series Editor, Dillmann, Rüdiger, Series Editor, Duan, Haibin, Series Editor, Ferrari, Gianluigi, Series Editor, Ferre, Manuel, Series Editor, Hirche, Sandra, Series Editor, Jabbari, Faryar, Series Editor, Jia, Limin, Series Editor, Kacprzyk, Janusz, Series Editor, Khamis, Alaa, Series Editor, Kroeger, Torsten, Series Editor, Liang, Qilian, Series Editor, Martin, Ferran, Series Editor, Ming, Tan Cher, Series Editor, Minker, Wolfgang, Series Editor, Misra, Pradeep, Series Editor, Möller, Sebastian, Series Editor, Mukhopadhyay, Subhas, Series Editor, Ning, Cun-Zheng, Series Editor, Nishida, Toyoaki, Series Editor, Pascucci, Federica, Series Editor, Qin, Yong, Series Editor, Seng, Gan Woon, Series Editor, Speidel, Joachim, Series Editor, Veiga, Germano, Series Editor, Wu, Haitao, Series Editor, Zhang, Junjie James, Series Editor, and (China SAE), China Society of Automotive Engineers, editor

Published
2020
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21. Topical Delivery of microRNA-125b by Framework Nucleic Acids for Psoriasis Treatment

Author

Han,Yunfeng, Xi,Long, Leng,Fang, Xu,Chenjie, Zheng,Ying, Han,Yunfeng, Xi,Long, Leng,Fang, Xu,Chenjie, and Zheng,Ying

Abstract

Yunfeng Han,1 Long Xi,1,2 Fang Leng,3 Chenjie Xu,3 Ying Zheng1 1State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau, 999078, People’s Republic of China; 2School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, 510006, People’s Republic of China; 3Department of Biomedical Engineering, City University of Hong Kong, Hong Kong SAR, People’s Republic of ChinaCorrespondence: Ying Zheng; Chenjie Xu, Tel +853 88224687 ; +852 34424169, Fax +853 28841358, Email yzheng@umac.mo; chenjie.xu@cityu.edu.hkPurpose: Psoriasis is a chronic and recurrent inflammatory dermatitis characterized by T cell imbalance and abnormal keratinocyte proliferation. MicroRNAs (miRNAs) hold promise as therapeutic agents for this disease; however, their clinical application is hindered by poor stability and limited skin penetration. This study demonstrates the utilization of Framework Nucleic Acid (FNA) for the topical delivery of miRNAs in psoriasis treatment.Methods: By utilizing miRNA-125b as the model drug, FNA-miR-125b was synthesized via self-assembly. The successful synthesis and stability of FNA-miR-125b in bovine fetal serum (FBS) were verified through gel electrophoresis. Subsequently, flow cytometry was employed to investigate the cell internalization on HaCaT cells, while qPCR determined the effects of FNA-miR-125b on cellular functions. Additionally, the skin penetration ability of FNA-miR-125b was assessed. Finally, a topical administration study involving FNA-miR-125b cream on imiquimod (IMQ)-induced psoriasis mice was conducted to evaluate its therapeutic efficacy.Results: The FNA-miR-125b exhibited excellent stability, efficient cellular internalization, and potent inhibition of keratinocyte proliferation. In the psoriasis mouse model, FNA-miR-125b effectively penetrated the skin tissue, resulting in reduced epidermal thickness and PASI score, as well as decreased levels of

Published
2024

23. Case report: Differential diagnosis of highly amplified anti-CD5 CAR T cells and relapsed lymphoma cells in a patient with refractory ALK positive anaplastic large cell lymphoma

Author

Mu, Wei, primary, Zhang, Meilan, additional, Hu, Guang, additional, Han, Yunfeng, additional, Mao, Xia, additional, Chen, Caixia, additional, Shen, Kefeng, additional, Dai, Zhenyu, additional, Zhu, Xiaojian, additional, Zhou, Xiaoxi, additional, Huang, Liang, additional, Ao, Qilin, additional, and Xiao, Min, additional

Published
2023
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38. Effect of berbamine hydrochloride on the absorption of berberine hydrochloride in an in situ single-pass intestinal perfusion system in rats

Author

Tang, Xi, Feng, Hui, Gao, Jie, Bi, Ruohong, Pan, Lin, Shi, Yi, Han, Yunfeng, and Lai, Xianrong

Subjects
Berberine, Berbamine, P-glycoprotein, One-way intestinal perfusion, digestive, oral, and skin physiology, Pharmaceutical Science, Pharmacology (medical)
Abstract

Purpose: To investigate the intestinal absorption characteristics of berberine hydrochloride (BBH) under different perfusion conditions in rats.Methods: Based on the in situ single-pass intestinal perfusion model of rats, HPLC was used to determine the content of berberine hydrochloride in solution after perfusion under different conditions. The absorption rate constant (Ka), effective permeability coefficient (Papp) and cumulative absorption per unit area (Q) under different perfusion conditions were analyzed by one-way ANOVA.Results: The Papp and Ka of BBH in perfusion solution at pH 7.4 were greater than those in perfusion solution at pH 6 and 8. There was no significant difference (p > 0.05) in Papp and Ka of duodenum, jejunum and ileum at high, medium and low concentrations of berberine hydrochloride perfusion solution. The Q increased linearly with increase of mass concentration of perfusion solution. The Ka and Papp of BBH in duodenum, jejunum, and ileum of BBH and berbamine hydrochloride (BAH) combined at different ratios were higher than those of BBH control group at the same BBH concentration, but absorption of BBH in the ratio B40:A50 and B30:A20 groups was highest. In the ratio of B40:A50 ratio, B30:A20 ratio group or the same concentration's BBH group, Ka and Papp of BBH decreased in the order of jejunum > duodenum > ileum.Conclusion: Berberine hydrochloride is absorbed in neutral environment of pH 7.4. The intestinal absorption mechanism of BBH is passive diffusion, and jejunum is the best intestinal segment for absorption. BAH promotes the absorption of BBH.

Published
2022

48. Impact of the COVID-19 Pandemic on the Professional Attitudes of Medical Students: A Pre-Post-Like Study

Author

Ma, Shuli, primary, Ge, Jie, additional, Qi, Yanbo, additional, Du, Linlin, additional, Han, Yunfeng, additional, Xie, Zhiping, additional, Li, Xingsan, additional, Li, Hongjie, additional, Chen, Zhe, additional, Chen, Xiaoting, additional, Tang, Xiaowei, additional, Li, Jiyuan, additional, Li, Jiping, additional, Xiao, Qiong, additional, Wu, Yu, additional, Gao, Ying, additional, Li, Wenting, additional, Liu, Lei, additional, and Jia, Yuehui, additional

Published
2023
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