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314 results on '"Han, Xiaoqiang"'

2. Research on Potential Relationship Between Personality Traits and Driving Anger of Hazmat Truck Drivers

Author

Wu, Sai, Shen, Xiaoyan, Lan, Qian, Han, Xiaoqiang, Sui, Xinyu, Dong, Xiangyong, Angrisani, Leopoldo, Series Editor, Arteaga, Marco, Series Editor, Chakraborty, Samarjit, Series Editor, Chen, Shanben, Series Editor, Chen, Tan Kay, Series Editor, Dillmann, Rüdiger, Series Editor, Duan, Haibin, Series Editor, Ferrari, Gianluigi, Series Editor, Ferre, Manuel, Series Editor, Hirche, Sandra, Series Editor, Jabbari, Faryar, Series Editor, Jia, Limin, Series Editor, Kacprzyk, Janusz, Series Editor, Khamis, Alaa, Series Editor, Kroeger, Torsten, Series Editor, Li, Yong, Series Editor, Liang, Qilian, Series Editor, Martín, Ferran, Series Editor, Ming, Tan Cher, Series Editor, Minker, Wolfgang, Series Editor, Misra, Pradeep, Series Editor, Mukhopadhyay, Subhas, Series Editor, Ning, Cun-Zheng, Series Editor, Nishida, Toyoaki, Series Editor, Oneto, Luca, Series Editor, Panigrahi, Bijaya Ketan, Series Editor, Pascucci, Federica, Series Editor, Qin, Yong, Series Editor, Seng, Gan Woon, Series Editor, Speidel, Joachim, Series Editor, Veiga, Germano, Series Editor, Wu, Haitao, Series Editor, Zamboni, Walter, Series Editor, Tan, Kay Chen, Series Editor, Wang, Wuhong, editor, Guo, Hongwei, editor, Jiang, Xiaobei, editor, Shi, Jian, editor, and Sun, Dongxian, editor

Published
2024
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21. Integrative Genomics and Bioactivity-Guided Isolation of Novel Antimicrobial Compounds from Streptomyces sp. KN37 in Agricultural Applications.

Author

Zhao, Jing, Li, Qinghua, Zeeshan, Muhammad, Zhang, Guoqiang, Wang, Chunjuan, Han, Xiaoqiang, and Yang, Desong

Subjects
AGRICULTURE, STREPTOMYCES, WHOLE genome sequencing, GENOMICS, ERWINIA, GENE clusters, ERWINIA amylovora
Abstract

Actinomycetes have long been recognized as an important source of antibacterial natural products. In recent years, actinomycetes in extreme environments have become one of the main research directions. Streptomyces sp. KN37 was isolated from the cold region of Kanas in Xinjiang. It demonstrated potent antimicrobial activity, but the primary active compounds remained unclear. Therefore, we aimed to combine genomics with traditional isolation methods to obtain bioactive compounds from the strain KN37. Whole-genome sequencing and KEGG enrichment analysis indicated that KN37 possesses the potential for synthesizing secondary metabolites, and 41 biosynthetic gene clusters were predicted, some of which showed high similarity to known gene clusters responsible for the biosynthesis of antimicrobial antibiotics. The traditional isolation methods and activity-guided fractionation were employed to isolate and purify seven compounds with strong bioactivity from the fermentation broth of the strain KN37. These compounds were identified as 4-(Diethylamino)salicylaldehyde (1), 4-Nitrosodiphenylamine (2), N-(2,4-Dimethylphenyl)formamide (3), 4-Nitrocatechol (4), Methylsuccinic acid (5), Phenyllactic acid (6) and 5,6-Dimethylbenzimidazole (7). Moreover, 4-(Diethylamino)salicylaldehyde exhibited the most potent inhibitory effect against Rhizoctonia solani, with an EC50 value of 14.487 mg/L, while 4-Nitrosodiphenylamine showed great antibacterial activity against Erwinia amylovora, with an EC50 value of 5.715 mg/L. This study successfully isolated several highly active antimicrobial compounds from the metabolites of the strain KN37, which could contribute as scaffolds for subsequent chemical synthesis. On the other hand, the newly predicted antibiotic-like substances have not yet been isolated, but they still hold significant research value. They are instructive in the study of active natural product biosynthetic pathways, activation of silent gene clusters, and engineering bacteria construction. [ABSTRACT FROM AUTHOR]

Published
2024
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50. Development Based on Unity3D Virtual Campus Roaming System

Author

Hu Yao, Li Jingwen, Han Xiaoqiang, and Yuan Jiao

Subjects
Environmental sciences, GE1-350
Abstract

Virtual Reality has become more and more eye-catching with the development of computer technology in recent years and has become one of the hot technologies. As an important branch of virtual reality, Virtual Campus provides a new way to browse the campus. It uses advanced equipment to simulate the scenes on campus through computer, and gives users a new browsing experience, allowing users to interact with the Internet through the Internet. This article takes the North China Institute of Technology as an example, through SketchUp, Unity3D In a combined way, the development and design of a three-dimensional virtual campus is carried out. A virtual campus system for human-computer interaction in North China Institute of Science and Technology was realized.

Published
2018
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