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335 results on '"Han, Weiguo"'

3. Initial development and testing of an exhaled microRNA detection strategy for lung cancer case–control discrimination

Author

Shi, Miao, Han, Weiguo, Loudig, Olivier, Shah, Chirag D., Dobkin, Jay B., Keller, Steven, Sadoughi, Ali, Zhu, Changcheng, Siegel, Robert E., Fernandez, Maria Katherine, DeLaRosa, Lizett, Patel, Dhruv, Desai, Aditi, Siddiqui, Taha, Gombar, Saurabh, Suh, Yousin, Wang, Tao, Hosgood, H. Dean, Pradhan, Kith, Ye, Kenny, and Spivack, Simon D.

Published
2023
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12. Sinus Surgery Is Associated with a Decrease in Aspirin-Induced Reaction Severity in Patients with Aspirin Exacerbated Respiratory Disease

Author

Jerschow, Elina, Edin, Matthew L., Chi, Yuling, Hurst, Beth, Abuzeid, Waleed M., Akbar, Nadeem A., Gibber, Marc, Fried, Marvin P., Han, Weiguo, Pelletier, Teresa, Ren, Zhen, Keskin, Taha, Roizen, Gigia, Lih, Fred B., Gruzdev, Artiom, Bradbury, J. Alyce, Schuster, Victor, Spivack, Simon, Rosenstreich, David, and Zeldin, Darryl C.

Published
2019
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14. Deletion of a 7-amino-acid region in the porcine epidemic diarrhea virus envelope protein induces higher type I and III interferon responses and results in attenuation in vivo

Author

Li, Zhiwei, primary, Ma, Zhiqian, additional, Han, Weiguo, additional, Chang, Chuanzhe, additional, Li, Yang, additional, Guo, Xuyang, additional, Zheng, Zifang, additional, Feng, Yingtong, additional, Xu, Lele, additional, Zheng, Haixue, additional, Wang, Xinglong, additional, and Xiao, Shuqi, additional

Published
2023
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24. Correction: A novel mechanism of regulation of the oncogenic transcription factor GLI3 by toll-like receptor signaling

Author

Matissek, Stephan J., primary, Karbalivand, Mona, additional, Han, Weiguo, additional, Boutilier, Ava, additional, Yzar-Garcia, Estefania, additional, Kehoe, Laura L., additional, Gardner, Devin Storm, additional, Hage, Adam, additional, Fleck, Krista, additional, Jeffers, Vicki, additional, Rajsbaum, Ricardo, additional, and Elsawa, Sherine F., additional

Published
2023
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30. Design and Implementation of GeoBrain Online Analysis System (GeOnAS)

Author

Han, Weiguo, Di, Liping, Zhao, Peisheng, Wei, Yaxing, Li, Xiaoyan, Hutchison, David, Series editor, Kanade, Takeo, Series editor, Kittler, Josef, Series editor, Kleinberg, Jon M., Series editor, Mattern, Friedemann, Series editor, Mitchell, John C., Series editor, Naor, Moni, Series editor, Nierstrasz, Oscar, Series editor, Pandu Rangan, C., Series editor, Steffen, Bernhard, Series editor, Sudan, Madhu, Series editor, Terzopoulos, Demetri, Series editor, Tygar, Doug, Series editor, Vardi, Moshe Y., Series editor, Weikum, Gerhard, Series editor, Bertolotto, Michela, editor, Ray, Cyril, editor, and Li, Xiang, editor

Published
2008
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31. Visual Exploratory Data Analysis of Traffic Volume

Author

Han, Weiguo, Wang, Jinfeng, Shaw, Shih-Lung, Hutchison, David, editor, Kanade, Takeo, editor, Kittler, Josef, editor, Kleinberg, Jon M., editor, Mattern, Friedemann, editor, Mitchell, John C., editor, Naor, Moni, editor, Nierstrasz, Oscar, editor, Pandu Rangan, C., editor, Steffen, Bernhard, editor, Sudan, Madhu, editor, Terzopoulos, Demetri, editor, Tygar, Dough, editor, Vardi, Moshe Y., editor, Weikum, Gerhard, editor, Carbonell, Jaime G., editor, Siekmann, Jörg, editor, Gelbukh, Alexander, editor, and Reyes-Garcia, Carlos Alberto, editor

Published
2006
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32. A novel mechanism of regulation of the oncogenic transcription factor GLI3 by toll-like receptor signaling

Author

Matissek, Stephan J., primary, Karbalivand, Mona, additional, Han, Weiguo, additional, Boutilier, Ava, additional, Yzar-Garcia, Estefania, additional, Kehoe, Laura L., additional, Gardner, Devin Storm, additional, Hage, Adam, additional, Fleck, Krista, additional, Jeffers, Vicki, additional, Rajsbaum, Ricardo, additional, and Elsawa, Sherine F., additional

Published
2022
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43. Molecular Engineering of Chalcogen‐Embedded Anthanthrenes via peri‐Selective C−H Activation: Fine‐Tuning of Crystal Packing for Organic Field‐Effect Transistors.

Author

Liu, Zheng, Han, Weiguo, Lan, Jingbo, Sun, Lingyan, Tang, Junbin, Zhang, Cheng, and You, Jingsong

Subjects
*ORGANIC field-effect transistors, *OXIDATIVE coupling, *FIELD-effect devices, *HOLE mobility, *ELECTRON mobility, *ELECTRON transport, *CHALCOGENS
Abstract

Disclosed herein is a RhCl3‐catalyzed peri‐selective C−H/C−H oxidative homo‐coupling of 1‐substituted naphthalenes, which provides a highly efficient and streamlined approach to chalcogen‐embedded anthanthrenes from readily available starting materials. Introducing O, S, and Se into the anthanthrene skeleton leads to gradually increased π–π stacking distances but significantly enhanced π–π overlaps with the growth of the hetero‐atom radius. Moderate π–π distance, overlap area, and intermolecular S−S interactions endow S‐embedded anthanthrene (PTT) with excellent 2D charge‐transport properties. Moreover, the transformation of p‐type to n‐type S‐embedded anthanthrenes is realized for the first time via the S‐atom oxidation from PTT to PTT‐O4. In organic field‐effect transistor devices, PTT derivatives exhibit hole transport with mobilities up to 1.1 cm2 V−1 s−1, while PTT‐O4 shows electron transport with a mobility of 0.022 cm2 V−1 s−1. [ABSTRACT FROM AUTHOR]

Published
2023
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49. Targeting Covalent and Non-Covalent Btki-Resistant CLL Using the Dual Irreversible/Reversible 4 th Generation BTK Inhibitor LP-168

Author

Gordon, Britten, Muhowski, Elizabeth, Ravikrishnan, Janani, Benrashid, Samon, Mitchell, Andrew, He, Alexander, Misra, Shrilekha, Lai, Tzung-Huei, Thangavadivel, Shanmugapriya, Marr, Alexander, Yu, Lianbo, Walker, Brandi, Perry, Elizabeth, Rogers, Kerry A, Kittai, Adam S, Bhat, Seema A, Byrd, John C., Sampath, Deepa, Lapalombella, Rosa, Han, Weiguo, Kay, Neil E., Chen, Yi, Tan, Fenlai, Anthony, Stephen P., Chen, Yu, and Woyach, Jennifer A.

Published
2023
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50. Candidate dietary phytochemicals modulate expression of phase II enzymes GSTP1 and NQO1 in human lung cells

Author

Tan, Xiang-Lin, Shi, Miao, Tang, Hui, Han, Weiguo, and Spivack, Simon D.

Subjects
Enzymes -- Research, Enzymes -- Physiological aspects, Phytochemicals -- Research, Phytochemicals -- Health aspects, Lungs -- Research, Lungs -- Physiological aspects, Food/cooking/nutrition
Abstract

Many phytochemicals possess cancer-preventive properties, some putatively through phase II metabolism-mediated mutagen/oxidant quenching. We applied human lung cells in vitro to investigate the effects of several candidate phytopreventive agents, including green tea extracts (GTE), broccoli sprout extracts (BSE), epigallocatechin gallate (EGCG), sulforaphane (SFN), phenethyl isothiocyanate (PEITC), and benzyl isothiocyanate (BITC), on inducing phase II enzymes glutathione S-transferase P1 (GSTP1) and NAD(P)H:quinone oxidoreductase 1 (NQ01) at mRNA and protein levels. Primary normal human bronchial epithelial cells (NHBE), immortalized human bronchial epithelial cells (HBEC), and lung adenocarcinoma cells (A549) were exposed to diet-achievable levels of GTE and BSE (0.5, 1.0, 2.0 mg/L), or individual index components EGCG, SFN, PEITC, BITC (0.5, 1.0, 2.0 [micro]mol/L) for 24 h, 48 h, and 6 d, respectively, mRNA assays employed RNA-specific quantitative RT-PCR and protein assays employed Western blotting. We found that in NHBE cells, while GSTP1 mRNA levels were slightly but significantly increased after exposure to GTE or BSE, NQ01 mRNA increased to 2- to 4-fold that of control when exposed to GTE, BSE, or SFN. Effects on NQ01 mRNA expression in HBEC cells were similar. NQ01 protein expression increased up to 11.8-fold in SFN-treated NHBE cells. Both GSTP1 and NO01 protein expression in A549 cells were constitutively high but not induced under any condition. Our results suggest that NQ01 is more responsive to the studied chemopreventive agents than GSTP1 in human lung cells and there is discordance between single agent and complex mixture effects. We conclude that modulation of lung cell phase II metabolism by chemopreventive agents requires cell- and agent-specific discovery and testing. doi: 10.3945/jn.110.121905.

Published
2010

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