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3. Social dominance and rainfall predict telomere dynamics in a cooperative arid-zone bird

Author

Wood, Emma M, Capilla-Lasheras, Pablo, Cram, Dominic L, Walker, Lindsay A, York, Jenny E, Lange, Anke, Hamilton, Patrick B, Tyler, Charles R, Young, Andrew J, Wood, Emma M [0000-0002-3609-4817], Capilla-Lasheras, Pablo [0000-0001-6091-7089], Cram, Dominic L [0000-0002-8790-8294], York, Jenny E [0000-0003-2808-9249], Lange, Anke [0000-0003-0665-8404], Young, Andrew J [0000-0003-0560-6549], and Apollo - University of Cambridge Repository

Subjects
reproduction, Social Dominance, life-history, Animals, telomere dynamics, Animals, Wild, Telomere, FOS: Medical biotechnology, somatic maintenance, Sparrows
Abstract

In many vertebrate societies dominant individuals breed at substantially higher rates than subordinates, but whether this hastens ageing remains poorly understood. While frequent reproduction may trade off against somatic maintenance, the extraordinary fecundity and longevity of some social insect queens highlight that breeders need not always suffer more rapid somatic deterioration than their nonbreeding subordinates. Here, we used extensive longitudinal assessments of telomere dynamics to investigate the impact of dominance status on within-individual age-related changes in somatic integrity in a wild social bird, the white-browed sparrow-weaver (Plocepasser mahali). Dominant birds, who monopolise reproduction, had neither shorter telomeres nor faster telomere attrition rates over the long-term (1-5 years) than their subordinates. However, over shorter (half-year) time intervals dominants with shorter telomeres showed lower rates of telomere attrition (and evidence suggestive of telomere lengthening), while the same was not true among subordinates. Dominants may therefore invest more heavily in telomere length regulation (and/or somatic maintenance more broadly); a strategy that could mitigate the long-term costs of reproductive effort, leaving their long-term telomere dynamics comparable to those of subordinates. Consistent with the expectation that reproduction entails short-term costs to somatic integrity, telomere attrition rates were most severe for all birds during the breeding seasons of wetter years (rainfall is the key driver of reproductive activity in this arid-zone species). Our findings suggest that, even in vertebrate societies in which dominants monopolise reproduction, dominants may experience long-term somatic integrity trajectories indistinguishable from those of their nonreproductive subordinates.

Published
2022

8. Social dominance and rainfall predict telomere dynamics in a cooperative arid‐zone bird.

Author

Wood, Emma M., Capilla‐Lasheras, Pablo, Cram, Dominic L., Walker, Lindsay A., York, Jenny E., Lange, Anke, Hamilton, Patrick B., Tyler, Charles R., and Young, Andrew J.

Subjects
TELOMERES, SOCIAL dominance, RAINFALL, QUEENS (Insects), INSECT societies, BIRD breeding
Abstract

In many vertebrate societies dominant individuals breed at substantially higher rates than subordinates, but whether this hastens ageing remains poorly understood. While frequent reproduction may trade off against somatic maintenance, the extraordinary fecundity and longevity of some social insect queens highlight that breeders need not always suffer more rapid somatic deterioration than their nonbreeding subordinates. Here, we used extensive longitudinal assessments of telomere dynamics to investigate the impact of dominance status on within‐individual age‐related changes in somatic integrity in a wild social bird, the white‐browed sparrow‐weaver (Plocepasser mahali). Dominant birds, who monopolise reproduction, had neither shorter telomeres nor faster telomere attrition rates over the long‐term (1–5 years) than their subordinates. However, over shorter (half‐year) time intervals dominants with shorter telomeres showed lower rates of telomere attrition (and evidence suggestive of telomere lengthening), while the same was not true among subordinates. Dominants may therefore invest more heavily in telomere length regulation (and/or somatic maintenance more broadly); a strategy that could mitigate the long‐term costs of reproductive effort, leaving their long‐term telomere dynamics comparable to those of subordinates. Consistent with the expectation that reproduction entails short‐term costs to somatic integrity, telomere attrition rates were most severe for all birds during the breeding seasons of wetter years (rainfall is the key driver of reproductive activity in this arid‐zone species). Our findings suggest that, even in vertebrate societies in which dominants monopolise reproduction, dominants may experience long‐term somatic integrity trajectories indistinguishable from those of their nonreproductive subordinates. [ABSTRACT FROM AUTHOR]

Published
2022
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10. Social dominance and rainfall predict telomere dynamics in a cooperative arid‐zone bird

Author

Wood, Emma M., Capilla‐Lasheras, Pablo, Cram, Dominic L., Walker, Lindsay A., York, Jenny E., Lange, Anke, Hamilton, Patrick B., Tyler, Charles R., Young, Andrew J., Wood, Emma M. [0000-0002-3609-4817], Capilla‐Lasheras, Pablo [0000-0001-6091-7089], Cram, Dominic L. [0000-0002-8790-8294], York, Jenny E. [0000-0003-2808-9249], Lange, Anke [0000-0003-0665-8404], Young, Andrew J. [0000-0003-0560-6549], and Apollo - University of Cambridge Repository

Subjects
reproduction, SPECIAL ISSUE: TELOMERES IN ECOLOGY AND EVOLUTION, social dominance, telomere dynamics, life‐history, somatic maintenance
Abstract

In many vertebrate societies dominant individuals breed at substantially higher rates than subordinates, but whether this hastens ageing remains poorly understood. While frequent reproduction may trade off against somatic maintenance, the extraordinary fecundity and longevity of some social insect queens highlight that breeders need not always suffer more rapid somatic deterioration than their nonbreeding subordinates. Here, we used extensive longitudinal assessments of telomere dynamics to investigate the impact of dominance status on within‐individual age‐related changes in somatic integrity in a wild social bird, the white‐browed sparrow‐weaver (Plocepasser mahali). Dominant birds, who monopolise reproduction, had neither shorter telomeres nor faster telomere attrition rates over the long‐term (1–5 years) than their subordinates. However, over shorter (half‐year) time intervals dominants with shorter telomeres showed lower rates of telomere attrition (and evidence suggestive of telomere lengthening), while the same was not true among subordinates. Dominants may therefore invest more heavily in telomere length regulation (and/or somatic maintenance more broadly); a strategy that could mitigate the long‐term costs of reproductive effort, leaving their long‐term telomere dynamics comparable to those of subordinates. Consistent with the expectation that reproduction entails short‐term costs to somatic integrity, telomere attrition rates were most severe for all birds during the breeding seasons of wetter years (rainfall is the key driver of reproductive activity in this arid‐zone species). Our findings suggest that, even in vertebrate societies in which dominants monopolise reproduction, dominants may experience long‐term somatic integrity trajectories indistinguishable from those of their nonreproductive subordinates.

Published
2021
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11. List of Contributors

Author

de Araujo-Jorge, Tania C., primary, Aufderheide, Arthur, additional, Apt, Werner, additional, Aznar, Christine, additional, Bargues, Maria Dolores, additional, Barnabé, Christian, additional, Barrias, Emile Santos, additional, Bartholomeu, Daniella C., additional, Basombrío, Miguel Angel, additional, Brenière, Simone Frédérique, additional, Buck, Gregory A., additional, Carlier, Yves, additional, de Carvalho, Tecia Maria Ulisses, additional, Corti, Marcelo, additional, de Rezende, Joffre Marcondes, additional, de Souza, Wanderley, additional, Desquesnes, Marc, additional, Docampo, Roberto, additional, Dorn, Patricia, additional, Dujardin, Jean-Pierre, additional, El-Sayed, Najib M.A., additional, Gorla, David, additional, Guhl, Felipe, additional, Hamilton, Patrick B., additional, Hontebeyrie, Mireille, additional, Jansen, Ana Maria, additional, de Lana, Marta, additional, Lewis, Michael D., additional, Luquetti, Alejandro O., additional, Llewellyn, Martin S., additional, Macedo, Andréa M., additional, Marcet, Paula, additional, Machado, Evandro Marques de Menezes, additional, Moreno, Silvia N.J., additional, Moncayo, Álvaro, additional, Monteiro, Fernando, additional, Miles, Michael A., additional, Noireau, François, additional, Patterson, James S., additional, Padilla, Angel Marcelo, additional, Brandan, Cecilia Perez, additional, Dias, João Carlos Pinto, additional, Ponce, Carlos, additional, Rassi, Anis, additional, Dalenz, Jaime Rios, additional, Roque, André Luiz Rodrigues, additional, Schmuñis, Gabriel A., additional, Schofield, C.J., additional, Segatto, Marcela, additional, Silveira, Antonio Carlos, additional, Stevens, Jamie R., additional, Svoboda, Michal, additional, Teixeira, Santuza M.R., additional, Telleria, Jenny, additional, Tibayrenc, Michel, additional, Truyens, Carine, additional, Villafañe, María F., additional, and Yeo, Matthew, additional

Published
2010
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13. Investigation into Adaptation in Genes Associated with Response to Estrogenic Pollution in Populations of Roach (Rutilus rutilus) Living in English Rivers

Author

Hamilton, Patrick B., primary, Lockyer, Anne E., additional, Uren Webster, Tamsyn M., additional, Studholme, David J., additional, Paris, Josephine R., additional, Baynes, Alice, additional, Nicol, Elizabeth, additional, Dawson, Deborah A., additional, Moore, Karen, additional, Farbos, Audrey, additional, Jobling, Susan, additional, Stevens, Jamie R., additional, and Tyler, Charles R., additional

Published
2020
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15. Evolution of non-kin cooperation:social assortment by cooperative phenotype in guppies

Author

Brask, Josefine Bohr, Croft, Darren P., Edenbrow, Mathew, James, Richard, Bleakley, Bronwyn H., Ramnarine, Indar W., Heathcote, Robert J. P., Tyler, Charles R., Hamilton, Patrick B., Dabelsteen, Torben, Darden, Safi K., Brask, Josefine Bohr, Croft, Darren P., Edenbrow, Mathew, James, Richard, Bleakley, Bronwyn H., Ramnarine, Indar W., Heathcote, Robert J. P., Tyler, Charles R., Hamilton, Patrick B., Dabelsteen, Torben, and Darden, Safi K.

Published
2019

16. Appendix A from Evolution of non-kin cooperation: social assortment by cooperative phenotype in guppies

Author

Brask, Josefine Bohr, Croft, Darren P., Edenbrow, Mathew, James, Richard, Bleakley, Bronwyn H., Indar W. Ramnarine, Heathcote, Robert J. P., Tyler, Charles R., Hamilton, Patrick B., Dabelsteen, Torben, and Safi K. Darden

Subjects
Hardware_INTEGRATEDCIRCUITS, ComputerApplications_COMPUTERSINOTHERSYSTEMS, Hardware_REGISTER-TRANSFER-LEVELIMPLEMENTATION, GeneralLiterature_MISCELLANEOUS, Hardware_LOGICDESIGN
Abstract

Validation of cooperativeness measure

Published
2018
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22. Methods, Gene Ontology tables and Sequence Alignment from Adaptive capabilities and fitness consequences associated with pollution exposure in fish

Author

Hamilton, Patrick B., Rolshausen, Gregor, Tamsyn M. Uren Webster, and Tyler, Charles R.

Subjects
animal structures, human activities, eye diseases
Abstract

Methods used for genotyping Cyp1A from guppies and methods used for RAD-seq analysis. Results for Gene Ontology analysis for RAD loci with FST > 0.75 are also given.

Published
2016
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23. New insights from Gorongosa National Park and Niassa National Reserve of Mozambique increasing the genetic diversity of Trypanosoma vivax and Trypanosoma vivax-like in tsetse flies, wild ungulates and livestock from East Africa

Author

Rodrigues, Carla MF, primary, Garcia, Herakles A, additional, Rodrigues, Adriana C, additional, Costa-Martins, André G, additional, Pereira, Carlos L, additional, Pereira, Dagmar L, additional, Bengaly, Zakaria, additional, Neves, Luis, additional, Camargo, Erney P, additional, Hamilton, Patrick B, additional, and Teixeira, Marta MG, additional

Published
2017
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24. The long shadow of our chemical past – high DDT concentrations in fish near a former agrochemicals factory in England

Author

Juergens, Monika D., Crosse, John, Hamilton, Patrick B., Johnson, Andrew C., Jones, Kevin C., Juergens, Monika D., Crosse, John, Hamilton, Patrick B., Johnson, Andrew C., and Jones, Kevin C.

Abstract

A total of 81 roach (Rutilus rutilus) collected from 13 southern English river sites between 2007 and 2012, were analysed for organochlorine pesticides, PCBs, PBDEs and some metals. Unexpectedly high concentrations of the banned insecticide DDT and its degradation products DDE and DDD (∑DDTs) were found in the 10 fish from the river Lee (or Lea) which averaged 88±70 (standard deviation) µg/kg ww, almost 20 times higher than the average for the remaining sites (4.8±3.1 µg/kg). All fish from that site exceeded the Canadian Tissue Residue Guideline (environmental quality standard) of 14 µg/kg ∑DDTs. Concentrations of the insecticides chlordane and lindane as well as copper, which is often used as a fungicide, were also elevated in fish from the Lee, though not as much as those of DDTs. A likely explanation for these observations was found in a nearby former pesticide factory, which had stopped production about three decades earlier. An extensive review of recent literature data on DDT in wild European fish found that, while levels are now generally low, there were several other hotspots with ∑DDTs levels that may still be of concern.

Published
2016

26. New insights into the evolution of the Trypanosoma cruzi clade provided by a new trypanosome species tightly linked to Neotropical Pteronotus bats and related to an Australian lineage of trypanosomes

Author

Lima, Luciana, primary, Espinosa-Álvarez, Oneida, additional, Pinto, C. Miguel, additional, Cavazzana, Manzelio, additional, Pavan, Ana Carolina, additional, Carranza, Julio C., additional, Lim, Burton K., additional, Campaner, Marta, additional, Takata, Carmen S. A., additional, Camargo, Erney P., additional, Hamilton, Patrick B., additional, and Teixeira, Marta M. G., additional

Published
2015
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28. Do stressful conditions make adaptation difficult? Guppies in the oil‐polluted environments of southern Trinidad

Author

Rolshausen, Gregor, primary, Phillip, Dawn A. T., additional, Beckles, Denise M., additional, Akbari, Ali, additional, Ghoshal, Subhasis, additional, Hamilton, Patrick B., additional, Tyler, Charles R., additional, Scarlett, Alan G., additional, Ramnarine, Indar, additional, Bentzen, Paul, additional, and Hendry, Andrew P., additional

Published
2015
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30. Populations of a cyprinid fish are self-sustaining despite widespread feminization of males

Author

Hamilton, Patrick B., Nicol, Elizabeth, De-Bastos, Eliane S.R., Williams, Richard J., Sumpter, John P., Jobling, Susan, Stevens, Jamie R., Tyler, Charles R., Hamilton, Patrick B., Nicol, Elizabeth, De-Bastos, Eliane S.R., Williams, Richard J., Sumpter, John P., Jobling, Susan, Stevens, Jamie R., and Tyler, Charles R.

Abstract

Background: Treated effluents from wastewater treatment works can comprise a large proportion of the flow of rivers in the developed world. Exposure to these effluents, or the steroidal estrogens they contain, feminizes wild male fish and can reduce their reproductive fitness. Long-term experimental exposures have resulted in skewed sex ratios, reproductive failures in breeding colonies, and population collapse. This suggests that environmental estrogens could threaten the sustainability of wild fish populations. Results: Here we tested this hypothesis by examining population genetic structures and effective population sizes (Ne) of wild roach (Rutilus rutilus L.) living in English rivers contaminated with estrogenic effluents. Ne was estimated from DNA microsatellite genotypes using approximate Bayesian computation and sibling assignment methods. We found no significant negative correlation between Ne and the predicted estrogen exposure at 28 sample sites. Furthermore, examination of the population genetic structure of roach in the region showed that some populations have been confined to stretches of river with a high proportion of estrogenic effluent for multiple generations and have survived, apparently without reliance on immigration of fish from less polluted sites. Conclusions: These results demonstrate that roach populations living in some effluent-contaminated river stretches, where feminization is widespread, are self-sustaining. Although we found no evidence to suggest that exposure to estrogenic effluents is a significant driving factor in determining the size of roach breeding populations, a reduction in Ne of up to 65% is still possible for the most contaminated sites because of the wide confidence intervals associated with the statistical model.

Published
2014

31. Microsatellite analysis supports clonal propagation and reduced divergence of Trypanosoma vivax from asymptomatic to fatally infected livestock in South America compared to West Africa

Author

Garcia, Herakles A, primary, Rodrigues, Adriana C, additional, Rodrigues, Carla MF, additional, Bengaly, Zakaria, additional, Minervino, Antonio HH, additional, Riet-Correa, Franklin, additional, Machado, Rosangela Z, additional, Paiva, Fernando, additional, Batista, Jael S, additional, Neves, Luis, additional, Hamilton, Patrick B, additional, and Teixeira, Marta MG, additional

Published
2014
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33. The phylogeography of trypanosomes from South American alligatorids and African crocodilids is consistent with the geological history of South American river basins and the transoceanic dispersal of Crocodylus at the Miocene

Author

Fermino, Bruno R, primary, Viola, Laerte B, additional, Paiva, Fernando, additional, Garcia, Herakles A, additional, de Paula, Catia D, additional, Botero-Arias, Robinson, additional, Takata, Carmen S A, additional, Campaner, Marta, additional, Hamilton, Patrick B, additional, Camargo, Erney P, additional, and Teixeira, Marta MG, additional

Published
2013
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36. Population-level consequences for wild fish exposed to sublethal concentrations of chemicals - a critical review.

Author

Hamilton, Patrick B, Cowx, Ian G, Oleksiak, Marjorie F, Griffiths, Andrew M, Grahn, Mats, Stevens, Jamie R, Carvalho, Gary R, Nicol, Elizabeth, and Tyler, Charles R

Subjects
*FISHES, *BIOMARKERS, *THREESPINE stickleback, *ROACH (Fish), *SEAFOOD, *MARICULTURE
Abstract

Concentrated chemical spills have been shown to impact adversely on fish populations and even cause localized population extinctions. Evaluating population-level impacts of sublethal exposure concentrations is, however, complex and confounded by other environmental pressures. Applying effect measures derived from laboratory-based chemical exposures to impacts in wild fish populations is constrained by uncertainty on how biochemical response measures (biomarkers) translate into health outcomes, lack of available data for chronic exposures and the many uncertainties in available fish population models. Furthermore, wild fish show phenotypic plasticity and local adaptations can occur that adds geographic and temporal variance on responses. Such population-level factors are rarely considered in the chemical risk assessment process and can probably be derived only from studies on wild fish. Molecular technologies, including microsatellite and SNP genotyping, and RNASeq for gene expression studies, are advancing our understanding of mechanisms of eco-toxicological response, tolerance, adaptation and selection in wild populations. We examine critically the application of such approaches with examples including using microsatellites that has identified roach ( Rutilus rutilus) populations living in rivers contaminated with sewage effluents that are self-sustaining, and studies of stickleback ( Gasterosteus aculeatus) and killifish ( Fundulus heteroclitus) that have identified genomic regions under selection putatively related to pollution tolerance. Integrating data on biological effects between laboratory-based studies and wild populations, and building understanding on adaptive responses to sublethal exposure are some of the priority research areas for more effective evaluation of population risks and resilience to contaminant exposure. [ABSTRACT FROM AUTHOR]

Published
2016
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37. Evolutionary Insights from Bat Trypanosomes: Morphological, Developmental and Phylogenetic Evidence of a New Species, Trypanosoma (Schizotrypanum) erneyi sp. nov., in African Bats Closely Related to Trypanosoma (Schizotrypanum) cruzi and Allied Species

Author

Lima, Luciana, primary, Silva, Flávia Maia da, additional, Neves, Luis, additional, Attias, Márcia, additional, Takata, Carmen S.A., additional, Campaner, Marta, additional, de Souza, Wanderley, additional, Hamilton, Patrick B., additional, and Teixeira, Marta M.G., additional

Published
2012
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43. Are Toxicological Responses in Laboratory (Inbred) Zebrafish Representative of Those in Outbred (Wild) Populations? − A Case Study with an Endocrine Disrupting Chemical

Author

Brown, A. Ross, primary, Bickley, Lisa K., additional, Le Page, Gareth, additional, Hosken, David John, additional, Paull, Gregory C., additional, Hamilton, Patrick B., additional, Owen, Stewart F., additional, Robinson, Joanna, additional, Sharpe, Alan D., additional, and Tyler, Charles R., additional

Published
2011
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