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Your search keyword '"Hamid, Yasser"' showing total 9 results
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9 results on '"Hamid, Yasser"'

5. Evaluation of the of the efficacy of Fractional Erbium-Doped Yttrium Aluminum Garnet Laser-Assisted Drug Delivery of Kojic Acid in the Treatment of Melasma; A split face, comparative clinical study

Author

Raya Hamid Yasser and Muhsin A. Al-Dhalimi

Subjects
medicine.medical_specialty, Randomization, Erythema, Melasma, chemistry.chemical_element, Lasers, Solid-State, Dermatology, Melanosis, Erbium, chemistry.chemical_compound, Ablative case, Humans, Medicine, business.industry, medicine.disease, Laser assisted, Treatment Outcome, chemistry, Pyrones, Drug delivery, Surgery, medicine.symptom, business, Kojic acid
Abstract

Melasma is a common, difficult to treat hyperpigmentary disorder. Recently, ablative fractional lasers were utilized to enhance topical agents delivery to treat different skin conditions. This work was designed to evaluate the efficacy of fractional Er:YAG laser in enhancing the effect of topical kojic acid in patients with facial melasma. The patients were randomly treated in a split-face mode, by simple randomization, either with kojic acid alone on one side or combined with fractional Er:YAG laser on the other side. Twenty five patients completed six laser sessions at 2 week interval. The severity of melasma was assessed before and after treatment in addition to 3 months follow up after the last treatment session. The response to the treatment was evaluated by Melasma Area and Severity Index Score, physician global assessment of photographs and patient satisfaction. The side treated with fractional Er:YAG laser and kojic acid cream was found to have a statistically significant better improvement than the side treated with kojic acid alone. The patients were reported mild tingling sensation and mild erythema on both sides. Using combination of fractional Er:YAG laser and topical kojic acid was effective in the treatment of melasma.

Published
2021

6. Assessment of The Role of Interleukin 6, C-Reactive Protein and high sensitive CReactive Protein in the Diagnosis of Early Onset Neonatal Sepsis (A clinical and Laboratory Approach.

Author

hamid, Yasser mustafa abdelazim abdel, Moniem, Ahmed Mohammed Abdel, Khalifa, Naglaa, and Elsafy, usama Roshdy

Subjects
*INTERLEUKINS, *C-reactive protein, *NEONATAL sepsis, *INTENSIVE care patients, *DETECTORS
Abstract

Background: Bacterial sepsis is a life threatening crisis with high mortality and morbidity in neonates, Reliable marker is needed for the diagnosis of neonatal sepsis. C-reactive protein (CRP), IL-6 can be used as Reliable markers for the diagnosis of neonatal sepsis so that early treatment could be achieved. Aim of the work: to detect the levels of IL-6, CRP and HS-CRP in clinically suspected cases of neonatal sepsis and evaluation and analysis of these measurments as early markers of neonatal sepsis. Patients and methods: A prospective cohort study was carried on 60 neonates at neonatal intensive care unit of pediatric department and clinical pathology department at Zagazig university hospitals. Results: IL-6 at a cut off value of 187.5Pg/ml had sensitivity of 87.5% and specificity of 63.6% with a negative predictive value of 93.3%. HS-CRP at a cut off value of 3.3 Mg/L had a higher sensitivity but a lower specificity at 100% and 47.7% repectively. CRP showed higher specificity than HS-CRP and IL-6 with 61.7% with a negative predictive value of 90%. A combination of IL-6 and CRP showed improvement of sensitivity to 100% and a negative predictive value of 100% and is more cost effective than the combination of IL-6 and HS-CRP which showed similar sensitivity and negative predictive value but showed less specificity Conclusion: a combination of IL-6 and HS-CRP would be a sensitive test for early diagnosis of neonatal sepsis at a sensitivity of 100% and a similar NPV, on the other hand a combination of IL-6 and CRP is less sensitive but more specific. [ABSTRACT FROM AUTHOR]

Published
2023
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