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313 results on '"Hamer, S."'

1. First detection of CO emission from Cepheid Variable stars

Author: Hamer, S. L., Ardern, S., and Scowcroft, V.
Subjects: Astrophysics - Solar and Stellar Astrophysics, Astrophysics - Astrophysics of Galaxies
Abstract: We present IRAM 30~m Telescope observations of the CO(1-0) and CO(2-1) emission lines in a sample of eight Cepheid variable stars. The CO(1-0) line is detected in four of the eight targets at a signal-to-noise of $>$3.5 confirming the presence of CO in Cepheid atmospheres. Two sources show strong absorption in both CO lines; this is likely related to contamination by cold molecular gas clouds along or close to the line of sight. The remaining two targets showed no strong features related to either CO line. These detections represent the first direct evidence for the presence of CO in Cepheid atmospheres, providing strong evidence for the mechanism proposed to explain the observed mid-infrared colour variation seen in Cepheids. Further, these detections support the proposed use of mid-IR colour as a robust photometric metallicity indicator for Cepheids, potentially leading to the elimination of metallicity systematics from the $H_0$ error budget. We discuss the future studies needed in this area and how our observations can be used to inform optimal observing strategies for large-scale dedicated studies., Comment: 5 pages, 1 figure. Submitted to MNRAS Letters
Published: 2023

2. Gas condensation in Brightest Group Galaxies unveiled with MUSE

Author: Olivares, V., Salome, P., Hamer, S. L., Combes, F., Gaspari, M., Kolokythas, K., O'Sullivan, E., Beckmann, R. S., Babul, A., Polles, F. L., Lehnert, M., Loubser, S. I., Donahue, M., Gendron-Marsolais, M. -L., Lagos, P., Forets, G. Pineau des, Godard, B., Rose, T., Tremblay, G., Ferland, G., and Guillard, P.
Subjects: Astrophysics - Astrophysics of Galaxies
Abstract: The origin of the cold gas in central galaxies in groups is still a matter of debate. We present Multi-Unit Spectroscopic Explorer (MUSE) observations of 18 optically selected local Brightest Group Galaxies (BGGs) to study the kinematics and distribution of the optical emission-line gas. MUSE observations reveal a distribution of gas morphologies including ten complex networks of filaments extending up to 10 kpc to two compact (<3 kpc) and five extended (>5 kpc) disk-dominated structures. Some rotating disks show rings and elongated structures arising from the central disk. The kinematics of the stellar component is mainly rotation-dominated, which is very different from the disturbed kinematics and distribution found in the filamentary sources. The ionized gas is kinematically decoupled from the stellar component for most systems, suggesting an external origin for the gas. We also find that the Halpha luminosity correlates with the cold molecular mass. By exploring the thermodynamical properties of the hot atmospheres, we find that the filamentary sources and compact disks are found in systems with small central entropy values and tcool/teddy ratios. This suggests that, like for Brightest Cluster Galaxies in cool core clusters, the ionized gas are likely formed from hot halo gas condensations, consistently with the Chaotic Cold Accretion simulations (as shown via the C-ratio, Tat, and k-plot). We note that gaseous rotating disks are more frequent than in BCGs. An explanation for the origin of the gas in those objects is a contribution to gas fueling by mergers or group satellites, as qualitatively hinted by some sources of the present sample. Nonetheless, we discuss the possibility that some extended disks could also be a transition stage in an evolutionary sequence including filaments, extended disks and compact disks, as described by hot gas condensation models of cooling flows., Comment: 38 pages, and 16 figures. Resubmitted to A&A after referee report
Published: 2022
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3. Excitation mechanisms in the intracluster filaments surrounding Brightest Cluster Galaxies

Author: Polles, F. L., Salomé, P., Guillard, P., Godard, B., Forêts, G. Pineau des, Olivares, V., Beckmann, R. S., Canning, R. E. A., Combes, F., Dubois, Y., Edge, A. C., Fabian, A. C., Ferland, G. J., Hamer, S. L., and Lehnert, M. D.
Subjects: Astrophysics - Astrophysics of Galaxies
Abstract: The excitation of the filamentary gas structures surrounding giant elliptical galaxies at the center of cool-core clusters, a.k.a BCGs (brightest cluster galaxies), is key to our understanding of active galactic nucleus feedback, and of the impact of environmental and local effects on star formation. We investigate the contribution of the thermal radiation from the cooling flow surrounding BCGs to the excitation of the filaments. We explore the effects of small levels of extra-heating (turbulence), and of metallicity, on the optical and infrared lines. Using the Cloudy code, we model the photoionization and photodissociation of a slab of gas of optical depth AV{\leq}30mag at constant pressure, in order to calculate self-consistently all of the gas phases, from ionized gas to molecular gas. The ionizing source is the EUV and soft X-ray radiation emitted by the cooling gas. We test these models comparing their predictions to the rich multi-wavelength observations, from optical to submillimeter. These models reproduce most of the multi-wavelength spectra observed in the nebulae surrounding the BCGs, not only the LINER-like optical diagnostics: [O iii]{\lambda} 5007 {\AA}/H\b{eta}, [N ii]{\lambda} 6583 {\AA}/H{\alpha} and ([S ii]{\lambda} 6716 {\AA}+[S ii]{\lambda} 6731 {\AA})/H{\alpha} but also the infrared emission lines from the atomic gas. The modeled ro-vib H2 lines also match observations, which indicates that near and mid-IR H2 lines are mostly excited by collisions between H2 molecules and secondary electrons produced naturally inside the cloud by the interaction between the X-rays and the cold gas in the filament. However, there is still some tension between ionized and molecular line tracers (i.e. CO), which requires to optimize the cloud structure and the density of the molecular zone., Comment: 16 pages, 9 figures, 3 tables. Accepted for publication in A&A
Published: 2021
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4. A molecular absorption line survey toward the AGN of Hydra-A

Author: Rose, Tom, Edge, A. C., Combes, F., Hamer, S., McNamara, B. R., Russell, H., Gaspari, M., Salomé, P., Sarazin, C., Tremblay, G. R., Baum, S. A., Bremer, M. N., Donahue, M., Fabian, A. C., Ferland, G., Nesvadba, N., O'Dea, C., Oonk, J. B. R., and Peck, A. B.
Subjects: Astrophysics - Astrophysics of Galaxies
Abstract: We present Atacama Large Millimeter/submillimeter Array observations of the brightest cluster galaxy Hydra-A, a nearby ($z=0.054$) giant elliptical galaxy with powerful and extended radio jets. The observations reveal CO(1-0), CO(2-1), $^{13}$CO(2-1), CN(2-1), SiO(5-4), HCO$^{+}$(1-0), HCO$^{+}$(2-1), HCN(1-0), HCN(2-1), HNC(1-0) and H$_{2}$CO(3-2) absorption lines against the galaxy's bright and compact active galactic nucleus. These absorption features are due to at least 12 individual molecular clouds which lie close to the centre of the galaxy and have velocities of approximately $-50$ to $+10$ km/s relative to its recession velocity, where positive values correspond to inward motion. The absorption profiles are evidence of a clumpy interstellar medium within brightest cluster galaxies composed of clouds with similar column densities, velocity dispersions and excitation temperatures to those found at radii of several kpc in the Milky Way. We also show potential variation in a $\sim 10$ km/s wide section of the absorption profile over a two year timescale, most likely caused by relativistic motions in the hot spots of the continuum source which change the background illumination of the absorbing clouds., Comment: Accepted for publication in MNRAS
Published: 2020
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5. Molecular gas in CLASH brightest cluster galaxies at $z\sim0.2-0.9$

Author: Castignani, G., Pandey-Pommier, M., Hamer, S. L., Combes, F., Salomé, P., Freundlich, J., and Jablonka, P.
Subjects: Astrophysics - Astrophysics of Galaxies, Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract: Brightest cluster galaxies (BCGs) are excellent laboratories to study galaxy evolution in dense Mpc-scale environments. We have observed in CO(1-0), CO(2-1), CO(3-2), or CO(4-3), with the IRAM-30m, 18 BCGs at $z\sim0.2-0.9$ that are drawn from the CLASH survey. Our sample includes RX1532, which is our primary target, being among the BCGs with the highest star formation rate (SFR$\gtrsim100~M_\odot$/yr) in the CLASH sample. We unambiguously detected both CO(1-0) and CO(3-2) in RX1532, yielding a large reservoir of molecular gas, $M_{H_2}=(8.7\pm1.1)\times10^{10}~M_\odot$, and a high level of excitation $r_{31}=0.75\pm0.12$. A morphological analysis of the HST I-band image of RX1532 reveals the presence of clumpy substructures both within and outside the half-light radius $r_e=(11.6\pm0.3)$ kpc, similarly to those found independently both in ultraviolet and in H$_\alpha$ in previous work. We tentatively detected CO(1-0) or CO(2-1) in four other BCGs, with molecular gas reservoirs in the range $M_{H_2}=2\times10^{10-11} M_\odot$. For the remaining 13 BCGs we set robust upper limits of $M_{H_2}/M_\star\lesssim0.1$, which are among the lowest molecular gas to stellar mass ratios found for distant ellipticals and BCGs. By comparison with distant cluster galaxies observed in CO our study shows that RX1532 ($M_{H_2}/M_\star = 0.40\pm0.05$) belongs to the rare population of star forming and gas-rich BCGs in the distant universe. By using available X-ray based estimates of the central intra-cluster medium entropy, we show that the detection of large reservoirs of molecular gas $M_{H_2}\gtrsim10^{10}~M_\odot$ in distant BCGs is possible when the two conditions are met: i) high SFR and ii) low central entropy, which favors the condensation and the inflow of gas onto the BCGs themselves, similarly to what has been previously found for some local BCGs., Comment: 16 pages, 8 figures, 4 tables, A&A in press
Published: 2020
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6. Dense gas formation and destruction in a simulated Perseus-like galaxy cluster with spin-driven black hole feedback

Author: Beckmann, R. S., Dubois, Y., Guillard, P., Salome, P., Olivares, V., Polles, F., Cadiou, C., Combes, F., Hamer, S., Lehnert, M. D., and Forets, G. Pineau des
Subjects: Astrophysics - Astrophysics of Galaxies, Astrophysics - High Energy Astrophysical Phenomena
Abstract: Extended filamentary H$\alpha$ emission nebulae are a striking feature of nearby galaxy clusters but the formation mechanism of the filaments, and the processes which shape their morphology remain unclear. We conduct an investigation into the formation, evolution and destruction of dense gas in the center of a simulated, Perseus-like, cluster under the influence of a spin-driven jet. We particularly study the role played by condensation of dense gas from the diffuse intracluster medium, and the impact of direct uplifting of existing dense gas by the jets, in determining the spatial distribution and kinematics of the dense gas. We present a hydrodynamical simulation of an idealised Perseus-like cluster using the adaptive mesh refinement code {\sc ramses}. Our simulation includes a supermassive black hole (SMBH) that self-consistently tracks its spin evolution via its local accretion, and in turn drives a large-scale jet whose direction is based on the black hole's spin evolution. We show that the formation and destruction of dense gas is closely linked to the SMBH's feedback cycle, and that its morphology is highly variable throughout the simulation. While extended filamentary structures readily condense from the hot intra-cluster medium, they are easily shattered into an overly clumpy distribution of gas during their interaction with the jet driven outflows. Condensation occurs predominantly onto infalling gas located 5 - 15 kpc from the center during quiescent phases of the central AGN, when the local ratio of the cooling time to free fall time falls below 20, i.e. when $t_{\rm cool}/t_{\rm ff} < 20$. We find evidence for both condensation and uplifting of dense gas, but caution that purely hydrodynamical simulations struggle to effectively regulate the cluster cooling cycle and produce overly clumpy distributions of dense gas morphologies, compared to observation., Comment: 18 pages, 17 Figures. Accepted for publication in A&A
Published: 2019
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7. Constraining cold accretion onto supermassive black holes: molecular gas in the cores of eight brightest cluster galaxies revealed by joint CO and CN absorption

Author: Rose, Tom, Edge, A. C., Combes, F., Gaspari, M., Hamer, S., Nesvadba, N., Peck, A. B., Sarazin, C., Tremblay, G. R., Baum, S. A., Bremer, M. N., McNamara, B. R., O'Dea, C., Oonk, J. B. R., Russell, H., Salomé, P., Donahue, M., Fabian, A. C., Ferland, G., Mittal, R., and Vantyghem, A.
Subjects: Astrophysics - Astrophysics of Galaxies
Abstract: To advance our understanding of the fuelling and feedback processes which power the Universe's most massive black holes, we require a significant increase in our knowledge of the molecular gas which exists in their immediate surroundings. However, the behaviour of this gas is poorly understood due to the difficulties associated with observing it directly. We report on a survey of 18 brightest cluster galaxies lying in cool cores, from which we detect molecular gas in the core regions of eight via carbon monoxide (CO), cyanide (CN) and silicon monoxide (SiO) absorption lines. These absorption lines are produced by cold molecular gas clouds which lie along the line of sight to the bright continuum sources at the galaxy centres. As such, they can be used to determine many properties of the molecular gas which may go on to fuel supermassive black hole accretion and AGN feedback mechanisms. The absorption regions detected have velocities ranging from -45 to 283 km s$^{-1}$ relative to the systemic velocity of the galaxy, and have a bias for motion towards the host supermassive black hole. We find that the CN N = 0 - 1 absorption lines are typically 10 times stronger than those of CO J = 0 - 1. This is due to the higher electric dipole moment of the CN molecule, which enhances its absorption strength. In terms of molecular number density CO remains the more prevalent molecule with a ratio of CO/CN $\sim 10$, similar to that of nearby galaxies. Comparison of CO, CN and HI observations for these systems shows many different combinations of these absorption lines being detected., Comment: Accepted for publication in MNRAS
Published: 2019
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8. Ubiquitous cold and massive filaments in cool core clusters

Author: Olivares, V., Salomé, P., Combes, F., Hamer, S., Guillard, P., Lehnert, M. D., Polles, F., Beckmann, R. S., Dubois, Y., Donahue, M., Edge, A., Fabian, A. C., McNamara, B., Rose, T., Russell, H., Tremblay, G., Vantyghem, A., Canning, R. E. A., Ferland, G., Godard, B., Hogan, M., Peirani, S., and Forets, G. Pineau des
Subjects: Astrophysics - Astrophysics of Galaxies
Abstract: Multi-phase filamentary structures around Brightest Cluster Galaxies are likely a key step of AGN-feedback. We observed molecular gas in 3 cool cluster cores: Centaurus, Abell S1101, and RXJ1539.5 and gathered ALMA and MUSE data for 12 other clusters. Those observations show clumpy, massive and long, 3--25 kpc, molecular filaments, preferentially located around the radio bubbles inflated by the AGN (Active Galactic Nucleus). Two objects show nuclear molecular disks. The optical nebula is certainly tracing the warm envelopes of cold molecular filaments. Surprisingly, the radial profile of the H$\alpha$/CO flux ratio is roughly constant for most of the objects, suggesting that (i) between 1.2 to 7 times more cold gas could be present and (ii) local processes must be responsible for the excitation. Projected velocities are between 100--400 km s$^{-1}$, with disturbed kinematics and sometimes coherent gradients. This is likely due to the mixing in projection of several thin unresolved filaments. The velocity fields may be stirred by turbulence induced by bubbles, jets or merger-induced sloshing. Velocity and dispersions are low, below the escape velocity. Cold clouds should eventually fall back and fuel the AGN. We compare the filament's radial extent, r$_{fil}$, with the region where the X-ray gas can become thermally unstable. The filaments are always inside the low-entropy and short cooling time region, where t$_{cool}$/t$_{ff}$<20 (9 of 13 sources). The range t$_{cool}$/t$_{ff}$, 8-23 at r$_{fil}$, is likely due to (i) a more complex gravitational potential affecting the free-fall time (e.g., sloshing, mergers); (ii) the presence of inhomogeneities or uplifted gas in the ICM, affecting the cooling time. For some of the sources, r$_{fil}$ lies where the ratio of the cooling time to the eddy-turnover time, t$_{cool}$/t$_{eddy}$, is approximately unity., Comment: 33 Pages, 17 Figures, submitted to A&A
Published: 2019
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9. Deep and narrow CO absorption revealing molecular clouds in the Hydra-A brightest cluster galaxy

Author: Rose, Tom, Edge, A. C., Combes, F., Gaspari, M., Hamer, S., Nesvadba, N., Russell, H., Tremblay, G. R., Baum, S. A., O'Dea, C., Peck, A. B., Sarazin, C., Vantyghem, A., Bremer, M., Donahue, M., Fabian, A. C., Ferland, G., McNamara, B. R., Mittal, R., Oonk, J. B. R., Salomé, P., Swinbank, A. M., and Voit, M.
Subjects: Astrophysics - Astrophysics of Galaxies
Abstract: Active galactic nuclei play a crucial role in the accretion and ejection of gas in galaxies. Although their outflows are well studied, finding direct evidence of accretion has proved very difficult and has so far been done for very few sources. A promising way to study the significance of cold accretion is by observing the absorption of an active galactic nucleus's extremely bright radio emission by the cold gas lying along the line-of-sight. As such, we present ALMA CO(1-0) and CO(2-1) observations of the Hydra-A brightest cluster galaxy (z=0.054) which reveal the existence of cold, molecular gas clouds along the line-of-sight to the galaxy's extremely bright and compact mm-continuum source. They have apparent motions relative to the central supermassive black hole of between -43 and -4 km s$^{-1}$ and are most likely moving along stable, low ellipticity orbits. The identified clouds form part of a $\sim$$10^{9}$ $\text{M}_{\odot}$, approximately edge-on disc of cold molecular gas. With peak CO(2-1) optical depths of $\tau$=0.88 $^{+0.06}_{-0.06}$, they include the narrowest and by far the deepest absorption of this type which has been observed to date in a brightest cluster galaxy. By comparing the relative strengths of the lines for the most strongly absorbing region, we are able to estimate a gas temperature of $42^{+25}_{-11}$ K and line-of-sight column densities of $N_{CO}=2^{+3}_{-1}\times 10 ^{17} cm^{-2}$ and $N_{ H_{2} }=7^{+10}_{-4}\times 10 ^{20} cm^{-2}$., Comment: 11 pages, 8 figures, accepted to MNRAS
Published: 2019
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10. Discovery of a diffuse optical line emitting halo in the core of the Centaurus cluster of galaxies: Line emission outside the protection of the filaments

Author: Hamer, S. L., Fabian, A. C., Russell, H. R., Salomé, P., Combes, F., Olivares, V., Polles, F. L., Edge, A. C., and Beckmann, R. S.
Subjects: Astrophysics - Cosmology and Nongalactic Astrophysics, Astrophysics - Astrophysics of Galaxies
Abstract: We present the discovery of diffuse optical line emission in the Centaurus cluster seen with the MUSE IFU. The unparalleled sensitivity of MUSE allows us to detect the faint emission from these structures which extend well beyond the bounds of the previously known filaments. Diffuse structures (emission surrounding the filaments, a northern shell and an extended Halo) are detected in many lines typical of the nebulae in cluster cores ([NII]$_{\lambda 6548\&6583}$ ,[SII]$_{\lambda 6716\&6731}$, [OI]$_{\lambda 6300}$, [OIII]$_{\lambda 4959\&5007}$ etc.) but are more than an order of magnitude fainter than the filaments, with the faint halo only detected through the brightest line in the spectrum ([NII]$_{\lambda 6583}$). These structures are shown to be kinematically distinct from the stars in the central galaxy and have different physical and excitation states to the filaments. Possible origins are discussed for each structure in turn and we conclude that shocks and/or pressure imbalances are resulting in gas dispersed throughout the cluster core, formed from either disrupted filaments or direct cooling, which is not confined to the bright filaments., Comment: 17 pages, 19 figures, Published in MNRAS
Published: 2018
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11. Revealing the velocity structure of the filamentary nebula in NGC 1275 in its entirety

Author: Gendron-Marsolais, M., Hlavacek-Larrondo, J., Martin, T. B., Drissen, L., McDonald, M., Fabian, A. C., Edge, A. C., Hamer, S. L., McNamara, B., and Morrison, G.
Subjects: Astrophysics - Astrophysics of Galaxies
Abstract: We have produced for the first time a detailed velocity map of the giant filamentary nebula surrounding NGC 1275, the Perseus cluster's brightest galaxy, and revealed a previously unknown rich velocity structure across the entire nebula. We present new observations of the low-velocity component of this nebula with the optical imaging Fourier transform spectrometer SITELLE at CFHT. With its wide field of view ($\sim$11'$\times$11'), SITELLE is the only integral field unit spectroscopy instrument able to cover the 80 kpc$\times$55 kpc (3.8'$\times$2.6') large nebula in NGC 1275. Our analysis of these observations shows a smooth radial gradient of the [N II]$\lambda$6583/$\text{H} \alpha$ line ratio, suggesting a change in the ionization mechanism and source across the nebula, while the dispersion profile shows a general decrease with increasing distance from the AGN at up to $\sim 10$ kpc. The velocity map shows no visible general trend or rotation, indicating that filaments are not falling uniformly onto the galaxy, nor being pulled out from it. Comparison between the physical properties of the filaments and Hitomi measurements of the X-ray gas dynamics in Perseus are also explored., Comment: 5 pages, 6 figures, submitted to MNRAS Letters
Published: 2018
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12. The MUSE Hubble Ultra Deep Field Survey: II. Spectroscopic redshifts and comparisons to color selections of high-redshift galaxies

Author: Inami, H., Bacon, R., Brinchmann, J., Richard, J., Contini, T., Conseil, S., Hamer, S., Akhlaghi, M., Bouche, N., Clement, B., Desprez, G., Drake, A. B., Hashimoto, T., Leclercq, F., Maseda, M., Michel-Dansac, L., Paalvast, M., Tresse, L., Ventou, E., Kollatschny, W., Boogaard, L. A., Finley, H., Marino, R. A., Schaye, J., and Wisotzki, L.
Subjects: Astrophysics - Astrophysics of Galaxies
Abstract: We have conducted a two-layered spectroscopic survey (1'x1' ultra deep and 3'x3' deep regions) in the Hubble Ultra Deep Field (HUDF) with the Multi Unit Spectroscopic Explorer (MUSE). The combination of a large field of view, high sensitivity, and wide wavelength coverage provides an order of magnitude improvement in spectroscopically confirmed redshifts in the HUDF; i.e., 1206 secure spectroscopic redshifts for HST continuum selected objects, which corresponds to 15% of the total (7904). The redshift distribution extends well beyond z>3 and to HST/F775W magnitudes as faint as ~30 mag (AB, 1-sigma). In addition, 132 secure redshifts were obtained for sources with no HST counterparts that were discovered in the MUSE data cubes by a blind search for emission-line features. In total, we present 1338 high quality redshifts, which is a factor of eight increase compared with the previously known spectroscopic redshifts in the same field. We assessed redshifts mainly with the spectral features [OII] at z<1.5 (473 objects) and Lya at 2.9~20% up to 28-29 mag and ~27 mag, respectively. We used the determined redshifts to test continuum color selection (dropout) diagrams of high-z galaxies. The selection condition for F336W dropouts successfully captures ~80% of the targeted z~2.7 galaxies. However, for higher redshift selections (F435W, F606W, and F775W dropouts), the success rates decrease to ~20-40%. We empirically redefine the selection boundaries to make an attempt to improve them to ~60%. The revised boundaries allow bluer colors that capture Lya emitters with high Lya equivalent widths falling in the broadbands used for the color-color selection. Along with this paper, we release the redshift and line flux catalog., Comment: 26 pages, 26 figures, 4 tables, accepted for publication in A&A (MUSE UDF Series Paper II), the redshift catalogs will be available at the CDS
Published: 2017
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13. Shaken Snow Globes: Kinematic Tracers of the Multiphase Condensation Cascade in Massive Galaxies, Groups, and Clusters

Author: Gaspari, M., McDonald, M., Hamer, S. L., Brighenti, F., Temi, P., Gendron-Marsolais, M., Hlavacek-Larrondo, J., Edge, A. C., Werner, N., Tozzi, P., Sun, M., Stone, J. M., Tremblay, G. R., Hogan, M. T., Eckert, D., Ettori, S., Yu, H., Biffi, V., and Planelles, S.
Subjects: Astrophysics - Astrophysics of Galaxies, Astrophysics - Cosmology and Nongalactic Astrophysics, Astrophysics - High Energy Astrophysical Phenomena, Physics - Computational Physics, Physics - Fluid Dynamics
Abstract: We propose a novel method to constrain turbulence and bulk motions in massive galaxies, groups and clusters, exploring both simulations and observations. As emerged in the recent picture of the top-down multiphase condensation, the hot gaseous halos are tightly linked to all other phases in terms of cospatiality and thermodynamics. While hot halos (10^7 K) are perturbed by subsonic turbulence, warm (10^4 K) ionized and neutral filaments condense out of the turbulent eddies. The peaks condense into cold molecular clouds (< 100 K) raining in the core via chaotic cold accretion (CCA). We show all phases are tightly linked via the ensemble (wide-aperture) velocity dispersion along the line of sight. The correlation arises in complementary long-term AGN feedback simulations and high-resolution CCA runs, and is corroborated by the combined Hitomi and new IFU measurements in Perseus cluster. The ensemble multiphase gas distributions are characterized by substantial spectral line broadening (100-200 km/s) with mild line shift. On the other hand, pencil-beam detections sample the small-scale clouds displaying smaller broadening and significant line shift up to several 100 km/s, with increased scatter due to the turbulence intermittency. We present new ensemble sigma_v of the warm Halpha+[NII] gas in 72 observed cluster/group cores: the constraints are consistent with the simulations and can be used as robust proxies for the turbulent velocities, in particular for the challenging hot plasma (otherwise requiring extremely long X-ray exposures). We show the physically motivated criterion C = t_cool/t_eddy ~ 1 best traces the condensation extent region and presence of multiphase gas in observed clusters/groups. The ensemble method can be applied to many available datasets and can substantially advance our understanding of multiphase halos in light of the next-generation multiwavelength missions., Comment: 18 pages, 5 figures, 2 tables; ApJ in press - typos corrected, formatting improved (new emulateapj mod included here)
Published: 2017
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14. Optical Emission Line Nebulae in Galaxy Cluster Cores 1: The Morphological, Kinematic and Spectral Properties of the Sample

Author: Hamer, S. L., Edge, A. C., Swinbank, A. M., Wilman, R. J., Combes, F., Salomé, P., Fabian, A. C., Crawford, C. S., Russell, H. R., Hlavacek-Larrondo, J., McNamara, B., and Bremer, M. N.
Subjects: Astrophysics - Astrophysics of Galaxies, Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract: We present an Integral Field Unit survey of 73 galaxy clusters and groups with the VIsible Multi Object Spectrograph (VIMOS) on VLT. We exploit the data to determine the H$\alpha$ gas dynamics on kpc-scales to study the feedback processes occurring within the dense cluster cores. We determine the kinematic state of the ionised gas and show that the majority of systems ($\sim$ 2/3) have relatively ordered velocity fields on kpc scales that are similar to the kinematics of rotating discs and are decoupled from the stellar kinematics of the Brightest Cluster Galaxy. The majority of the H$\alpha$ flux ($>$ 50%) is typically associated with these ordered kinematics and most systems show relatively simple morphologies suggesting they have not been disturbed by a recent merger or interaction. Approximately 20% of the sample (13/73) have disturbed morphologies which can typically be attributed to AGN activity disrupting the gas. Only one system shows any evidence of an interaction with another cluster member. A spectral analysis of the gas suggests that the ionisation of the gas within cluster cores is dominated by non stellar processes, possibly originating from the intracluster medium itself., Comment: 36 pages, 25 figures. Appendices available at http://aramis.obspm.fr/~hamer/igigcc/ionised_gas_in_cluster_cores_appendices.pdf (75 pages, supplementary figures and data tables)
Published: 2016
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15. A Comprehensive Study of the Radio Properties of Brightest Cluster Galaxies

Author: Hogan, M. T., Edge, A. C., Hlavacek-Larrondo, J., Grainge, K. J. B., Hamer, S. L., Mahony, E. K., Russell, H. R., Fabian, A. C., McNamara, B. R., and Wilman, R. J.
Subjects: Astrophysics - Astrophysics of Galaxies
Abstract: We examine the radio properties of the Brightest Cluster Galaxies (BCGs) in a large sample of X-ray selected galaxy clusters comprising the Brightest Cluster Sample (BCS), the extended BCS (eBCS) and ROSAT-ESO Flux Limited X-ray (REFLEX) cluster catalogues. We have multi-frequency radio observations of the BCG using a variety of data from the Australia Telescope Compact Array (ATCA), Jansky Very Large Array (VLA) and Very Long Baseline Array (VLBA) telescopes. The radio spectral energy distributions (SEDs) of these objects are decomposed into a component attributed to on-going accretion by the active galactic nuclei (AGN) that we refer to as the 'core', and a more diffuse, ageing component we refer to as the 'non-core'. These BCGs are matched to previous studies to determine whether they exhibit emission lines (principally H-alpha), indicative of the presence of a strong cooling cluster core. We consider how the radio properties of the BCGs vary with cluster environmental factors. Line emitting BCGs are shown to generally host more powerful radio sources, exhibiting the presence of a strong, distinguishable core component in about 60% of cases. This core component more strongly correlates with the BCG's [OIII]5007A line emission. For BCGs in line-emitting clusters, the X-ray cavity power correlates with both the extended and core radio emission, suggestive of steady fuelling of the AGN over bubble-rise time-scales in these clusters., Comment: 24 pages (+44 pages of Appendices), 16 figures, 10 tables (of which 8 in Appendices). Accepted for publication in MNRAS
Published: 2015
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16. Cold gas in group-dominant elliptical galaxies

Author: O'Sullivan, E., Combes, F., Hamer, S., Salomé, P., Babul, A., and Raychaudhury, S.
Subjects: Astrophysics - Astrophysics of Galaxies
Abstract: We present IRAM 30m telescope observations of the CO(1-0) and (2-1) lines in a sample of 11 group-dominant elliptical galaxies selected from the CLoGS nearby groups sample. Our observations confirm the presence of molecular gas in 4 of the 11 galaxies at >4 sigma significance, and combining these with data from the literature we find a detection rate of 43+-14%, comparable to the detection rate for nearby radio galaxies, suggesting that group-dominant ellipticals may be more likely to contain molecular gas than their non-central counterparts. Those group-dominant galaxies which are detected typically contain ~2x10^8 Msol of molecular gas, and although most have low star formation rates (<1 Msol/yr) they have short depletion times, indicating that the gas must be replenished on timescales ~100 Myr. Almost all of the galaxies contain active nuclei, and we note while the data suggest that CO may be more common in the most radio-loud galaxies, the mass of molecular gas required to power the active nuclei through accretion is small compared to the masses observed. We consider possible origin mechanisms for the gas, through cooling of stellar ejecta within the galaxies, group-scale cooling flows, and gas-rich mergers, and find probable examples of each type within our sample, confirming that a variety of processes act to drive the build up of molecular gas in group-dominant ellipticals., Comment: 9 pages, 5 postscript figures, 4 tables, accepted by A&A. Revised throughout in response to referee's comments, including updates to Table 1 and Figure 4, and addition of Figure 5
Published: 2014
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17. A $10^{10}$ Solar Mass Flow of Molecular Gas in the Abell 1835 Brightest Cluster Galaxy

Author: McNamara, B. R., Russell, H. R., Nulsen, P. E. J., Edge, A. C., Murray, N. W., Main, R. A., Vantyghem, A. N., Combes, F., Fabian, A. C., Salome, P., Kirkpatrick, C. C., Baum, S. A., Bregman, J. N., Donahue, M., Egami, E., Hamer, S., O'Dea, C. P., Oonk, J. B. R., Tremblay, G., and Voit, G. M.
Subjects: Astrophysics - Galaxy Astrophysics
Abstract: We report ALMA Early Science observations of the Abell 1835 brightest cluster galaxy (BCG) in the CO (3-2) and CO (1-0) emission lines. We detect $5\times 10^{10}~\rm M_\odot$ of molecular gas within 10 kpc of the BCG. Its ensemble velocity profile width of $\sim 130 ~\rm km~s^{-1}$ FWHM is too narrow for the molecular cloud sto be supported in the galaxy by dynamic pressure. The gas may instead be supported in a rotating, turbulent disk oriented nearly face-on. Roughly $10^{10}~\rm M_\odot$ of molecular gas is projected $3-10 ~\rm kpc$ to the north-west and to the east of the nucleus with line of sight velocities lying between $-250 ~\rm km~s^{-1}$ to $+480 ~\rm km~s^{-1}$ with respect to the systemic velocity. The high velocity gas may be either inflowing or outflowing. However, the absence of high velocity gas toward the nucleus that would be expected in a steady inflow, and its bipolar distribution on either side of the nucleus, are more naturally explained as outflow. Star formation and radiation from the AGN are both incapable of driving an outflow of this magnitude. If so, the molecular outflow may be associated a hot outflow on larger scales reported by Kirkpatrick and colleagues. The molecular gas flow rate of approximately $200~\rm M_\odot ~yr^{-1}$ is comparable to the star formation rate of $100-180~\rm M_\odot ~yr^{-1}$ in the central disk. How radio bubbles would lift dense molecular gas in their updrafts, how much gas will be lost to the BCG, and how much will return to fuel future star formation and AGN activity are poorly understood. Our results imply that radio-mechanical (radio mode) feedback not only heats hot atmospheres surrounding elliptical galaxies and BCGs, it is able to sweep higher density molecular gas away from their centers., Comment: To appear in ApJ -- expanded discussion of inflow/outflow added to submitted version
Published: 2014

18. Cold gas dynamics in Hydra-A: evidence for a rotating disk

Author: Hamer, S. L., Edge, A. C., Swinbank, A. M., Oonk, J. B. R., Mittal, R., McNamara, B. R., Russell, H. R., Bremer, M. N., Combes, F., Fabian, A. C., Nesvadba, N. P. H., O'Dea, C. P., Baum, S. A., Salomé, P., Tremblay, G., Donahue, M., Ferland, G. J., and Sarazin, C. L.
Subjects: Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract: We present multi-frequency observations of the radio galaxy Hydra-A (3C218) located in the core of a massive, X-ray luminous galaxy cluster. IFU spectroscopy is used to trace the kinematics of the ionised and warm molecular hydrogen which are consistent with a ~ 5 kpc rotating disc. Broad, double-peaked lines of CO(2-1), [CII]157 $\mu$m and [OI]63 $\mu$m are detected. We estimate the mass of the cold gas within the disc to be M$_{gas}$ = 2.3 $\pm$ 0.3 x 10$^9$ M$_{\odot}$. These observations demonstrate that the complex line profiles found in the cold atomic and molecular gas are related to the rotating disc or ring of gas. Finally, an HST image of the galaxy shows that this gas disc contains a substantial mass of dust. The large gas mass, SFR and kinematics are consistent with the levels of gas cooling from the ICM. We conclude that the cold gas originates from the continual quiescent accumulation of cooled ICM gas. The rotation is in a plane perpendicular to the projected orientation of the radio jets and ICM cavities hinting at a possible connection between the kpc-scale cooling gas and the accretion of material onto the black hole. We discuss the implications of these observations for models of cold accretion, AGN feedback and cooling flows., Comment: Accepted for publication in MNRAS on October 9 2013
Published: 2013
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19. A Ten Billion Solar Mass Outflow of Molecular Gas Launched by Radio Bubbles in the Abell 1835 Brightest Cluster Galaxy

Author: McNamara, B. R., Russell, H. R., Nulsen, P. E. J., Edge, A. C., Murray, N. W., Main, R. A., Vantyghem, A. N., Combes, F., Fabian, A. C., Salome, P., Kirkpatrick, C. C., Baum, S. A., Bregman, J. N., Donahue, M., Egami, E., Hamer, S., O'Dea, C. P., Oonk, J. B. R., Tremblay, G., and Voit, G. M.
Subjects: Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract: We report ALMA Early Science observations of the Abell 1835 brightest cluster galaxy (BCG) in the CO (3-2) and CO (1-0) emission lines. We detect 5E10 solar masses of molecular gas within 10 kpc of the BCG. Its velocity width of ~130 km/s FWHM is too narrow to be supported by dynamical pressure. The gas may instead be supported in a rotating, turbulent disk oriented nearly face-on. The disk is forming stars at a rate of 100-180 solar masses per year. Roughly 1E10 solar masses of molecular gas is projected 3-10 kpc to the north-west and to the east of the nucleus with line of sight velocities lying between -250 km/s to +480 km/s with respect to the systemic velocity. Although inflow cannot be ruled out, the rising velocity gradient with radius is consistent with a broad, bipolar outflow driven by radio jets or buoyantly rising X-ray cavities. The molecular outflow may be associated with an outflow of hot gas in Abell 1835 seen on larger scales. Molecular gas is flowing out of the BCG at a rate of approximately 200 solar masses per year, which is comparable to its star formation rate. How radio bubbles lift dense molecular gas in their updrafts, how much gas will be lost to the BCG, and how much will return to fuel future star formation and AGN activity are poorly understood. Our results imply that radio-mechanical (radio mode) feedback not only heats hot atmospheres surrounding elliptical galaxies and BCGs, it is able to sweep higher density molecular gas away from their centers., Comment: Five Figures, submitted to ApJ
Published: 2013
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20. The Relation Between Line Emission and Brightest Cluster Galaxies in Three Exceptional Clusters: Evidence for Gas Cooling from the ICM

Author: Hamer, S. L., Edge, A. C., Swinbank, A. M., Wilman, R. J., Russell, H. R., Fabian, A. C., Sanders, J. S., and Salom, P.
Subjects: Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract: There is a strong spatial correlation between brightest cluster galaxies (BCGs) and the peak density and cooling rate of the intra-cluster medium (ICM). In this paper we combine integral field spectroscopy, CO observations and X-ray data to study three exceptional clusters (Abell 1991, Abell 3444 and Ophiuchus) where there is a physical and dynamical offset between the BCG and the cooling peak to investigate the connection between the cooling of the intracluster medium, the cold gas being deposited and the central galaxy. We find the majority of the optical line emission is spatially coincident with the peak in the soft X-rays. In the case of A1991 we make separate detections of CO(2-1) emission on the BCG and on the peak of the soft X-ray emission suggesting that cooling continues to occur in the core despite being offset from the BCG. We conclude that there is a causal link between the lowest temperature (< 2 keV) ICM gas and the molecular gas(~ 30K). This link is only apparent in systems where a transitory event has decoupled the BCG from the soft X-ray peak. We discuss the prospects for identifying more examples of this rare configuration., Comment: 11 pages, 7 figures, 2 tables, Resubmitted to MN after addressing referees comments
Published: 2011
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21. Herschel photometry of brightest cluster galaxies in cooling flow clusters

Author: Edge, A. C., Oonk, J. B. R., Mittal, R., Allen, S. W., Baum, S. A., Boehringer, H., Bregman, J. N., Bremer, M. N., Combes, F., Crawford, C. S., Donahue, M., Egami, E., Fabian, A. C., Ferland, G. J., Hamer, S. L., Hatch, N. A., Jaffe, W., Johnstone, R. M., McNamara, B. R., O'Dea, C. P., Popesso, P., Quillen, A. C., Salome, P., Sarazin, C. L., Voit, G. M., Wilman, R. J., and Wise, M. W.
Subjects: Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract: The dust destruction timescales in the cores of clusters of galaxies are relatively short given their high central gas densities. However, substantial mid-infrared and sub-mm emission has been detected in many brightest cluster galaxies. In this letter we present Herschel PACS and SPIRE photometry of the brightest cluster galaxy in three strong cooling flow clusters, A1068, A2597 and Zw3146. This photometry indicates that a substantial mass of cold dust is present (>3 x 10^7 Mo) at temperatures significantly lower (20-28K) than previously thought based on limited MIR and/or sub-mm results. The mass and temperature of the dust appear to match those of the cold gas traced by CO with a gas-to-dust ratio of 80-120., Comment: Accepted for A&A Herschel Special Issue, 7 pages, 3 figures
Published: 2010
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22. Herschel observations of FIR emission lines in brightest cluster galaxies

Author: Edge, A. C., Oonk, J. B. R., Mittal, R., Allen, S. W., Baum, S. A., Boehringer, H., Bregman, J. N., Bremer, M. N., Combes, F., Crawford, C. S., Donahue, M., Egami, E., Fabian, A. C., Ferland, G. J., Hamer, S. L., Hatch, N. A., Jaffe, W., Johnstone, R. M., McNamara, B. R., O'Dea, C. P., Popesso, P., Quillen, A. C., Salome, P., Sarazin, C. L., Voit, G. M., Wilman, R. J., and Wise, M. W.
Subjects: Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract: The question of how much gas cools in the cores of clusters of galaxies has been the focus of many, multiwavelength studies in the past 30 years. In this letter we present the first detections of the strongest atomic cooling lines, [C II], [O I] and [N I] in two strong cooling flow clusters, A1068 and A2597, using Herschel PACS. These spectra indicate that the substantial mass of cold molecular gas (>10^9 Mo) known to be present in these systems is being irradiated by intense UV radiation, most probably from young stars. The line widths of these FIR lines indicate that they share dynamics similar but not identical to other ionised and molecular gas traced by optical, near-infrared and CO lines. The relative brightness of the FIR lines compared to CO and FIR luminosity is consistent with other star-forming galaxies indicating that the properties of the molecular gas clouds in cluster cores and the stars they form are not unusual. These results provide additional evidence for a reservoir of cold gas that is fed by the cooling of gas in the cores of the most compact clusters and provide important diagnostics of the temperature and density of the dense clouds this gas resides in., Comment: Accepted for the A&A Herschel Special Issue, 5 pages, 2 figures
Published: 2010
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23. Gas condensation in brightest group galaxies unveiled with MUSE

Author: Olivares, V., primary, Salomé, P., additional, Hamer, S. L., additional, Combes, F., additional, Gaspari, M., additional, Kolokythas, K., additional, O’Sullivan, E., additional, Beckmann, R. S., additional, Babul, A., additional, Polles, F. L., additional, Lehnert, M., additional, Loubser, S. I., additional, Donahue, M., additional, Gendron-Marsolais, M.-L., additional, Lagos, P., additional, Pineau des Forets, G., additional, Godard, B., additional, Rose, T., additional, Tremblay, G., additional, Ferland, G., additional, and Guillard, P., additional
Published: 2022
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24. Leading teams during simulated pediatric emergencies: a pilot study

Author: Coolen EH, Draaisma JM, den Hamer S, and Loeffen JL
Subjects: Special aspects of education, LC8-6691, Medicine (General), R5-920
Abstract: Ester H Coolen,1 Jos M Draaisma,2 Sabien den Hamer,3 Jan L Loeffen2 1Department of Pediatric Surgery, Amalia Children’s Hospital, Radboud University Medical Center, 2Department of Pediatrics, Amalia Children’s Hospital, Radboud University Medical Center, 3Department of Communication Science, Radboud University, Nijmegen, the Netherlands Purpose: Leadership has been identified as a key variable for the functioning of teams and as one of the main reasons for success or failure of team-based work systems. Pediatricians often function as team leaders in the resuscitation of a critically ill child. However, pediatric residents often report having little opportunity to perform in the role of team leader during residency. In order to gain more insight into leadership skills and behaviors, we classified leadership styles of pediatric residents during simulated emergencies. Methods: We conducted a prospective quantitative study to investigate leadership styles used by pediatric residents during simulated emergencies with clinical deterioration of a child at a pediatric ward. Using videotaped scenarios of 48 simulated critical events among 12 residents, we were able to classify verbal and nonverbal communication into different leadership styles according to the situational leadership theory. Results: The coaching style (mean 54.5%, SD 7.8) is the most frequently applied by residents, followed by the directing style (mean 35.6%, SD 4.1). This pattern conforms to the task- and role-related requirements in our scenarios and it also conforms to the concept of situational leadership. We did not find any significant differences in leadership style according to the postgraduate year or scenario content. Conclusion: The model used in this pilot study helps us to gain a better understanding of the development of effective leadership behavior and supports the applicability of situational leadership theory in training leadership skills during residency. Keywords: leadership, residency, medical education, simulation, emergencies
Published: 2015

25. The relationship between colour vision loss, contrast sensitivity loss and aging

Author: Vaegan, A., Banks, A., Gathy, A., Hamer, S., Phonesouk, S., Perry, S., Capon, M., and Drum, B., editor
Published: 1993
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26. Excitation mechanisms in the intracluster filaments surrounding brightest cluster galaxies

Author: Polles, F. L., primary, Salomé, P., additional, Guillard, P., additional, Godard, B., additional, Pineau des Forêts, G., additional, Olivares, V., additional, Beckmann, R. S., additional, Canning, R. E. A., additional, Combes, F., additional, Dubois, Y., additional, Edge, A. C., additional, Fabian, A. C., additional, Ferland, G. J., additional, Hamer, S. L., additional, and Lehnert, M. D., additional
Published: 2021
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27. Shiitake dermatitis with oral ulceration and pustules

Author: Hamer, S. E., Kulkarni, K., and Cohen, S. N.
Published: 2015
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28. COVID-19 vaccine coverage in health-care workers in England and effectiveness of BNT162b2 mRNA vaccine against infection (SIREN): a prospective, multicentre, cohort study

Author: Hall, Victoria Jane, primary, Foulkes, Sarah, additional, Saei, Ayoub, additional, Andrews, Nick, additional, Oguti, Blanche, additional, Charlett, Andre, additional, Wellington, Edgar, additional, Stowe, Julia, additional, Gillson, Natalie, additional, Atti, Ana, additional, Islam, Jasmin, additional, Karagiannis, Ioannis, additional, Munro, Katie, additional, Khawam, Jameel, additional, Chand, Meera A, additional, Brown, Colin S, additional, Ramsay, Mary, additional, Lopez-Bernal, Jamie, additional, Hopkins, Susan, additional, Andrews, N, additional, Atti, A, additional, Aziz, H, additional, Brooks, T, additional, Brown, CS, additional, Camero, D, additional, Carr, C, additional, Chand, MA, additional, Charlett, A, additional, Crawford, H, additional, Cole, M, additional, Conneely, J, additional, D'Arcangelo, S, additional, Ellis, J, additional, Evans, S, additional, Foulkes, S, additional, Gillson, N, additional, Gopal, R, additional, Hall, L, additional, Hall, VJ, additional, Harrington, P, additional, Hopkins, S, additional, Hewson, J, additional, Hoschler, K, additional, Ironmonger, D, additional, Islam, J, additional, Kall, M, additional, Karagiannis, I, additional, Kay, O, additional, Khawam, J, additional, King, E, additional, Kirwan, P, additional, Kyffin, R, additional, Lackenby, A, additional, Lattimore, M, additional, Linley, E, additional, Lopez-Bernal, J, additional, Mabey, L, additional, McGregor, R, additional, Miah, S, additional, Monk, EJM, additional, Munro, K, additional, Naheed, Z, additional, Nissr, A, additional, O'Connell, AM, additional, Oguti, B, additional, Okafor, H, additional, Organ, S, additional, Osbourne, J, additional, Otter, A, additional, Patel, M, additional, Platt, S, additional, Pople, D, additional, Potts, K, additional, Ramsay, M, additional, Robotham, J, additional, Rokadiya, S, additional, Rowe, C, additional, Saei, A, additional, Sebbage, G, additional, Semper, A, additional, Shrotri, M, additional, Simmons, R, additional, Soriano, A, additional, Staves, P, additional, Taylor, S, additional, Taylor, A, additional, Tengbe, A, additional, Tonge, S, additional, Vusirikala, A, additional, Wallace, S, additional, Wellington, E, additional, Zambon, M, additional, Corrigan, D, additional, Sartaj, M, additional, Cromey, L, additional, Campbell, S, additional, Braithwaite, K, additional, Price, L, additional, Haahr, L, additional, Stewart, S, additional, Lacey, ED, additional, Partridge, L, additional, Stevens, G, additional, Ellis, Y, additional, Hodgson, H, additional, Norman, C, additional, Larru, B, additional, Mcwilliam, S, additional, Roynon, A, additional, Northfield, J, additional, Winchester, S, additional, Cieciwa, P, additional, Pai, A, additional, Bakker, P, additional, Loughrey, C, additional, Watt, A, additional, Adair, F, additional, Hawkins, A, additional, Grant, A, additional, Temple-Purcell, R, additional, Howard, J, additional, Slawson, N, additional, Subudhi, C, additional, Davies, S, additional, Bexley, A, additional, Penn, R, additional, Wong, N, additional, Boyd, G, additional, Rajgopal, A, additional, Arenas-Pinto, A, additional, Matthews, R, additional, Whileman, A, additional, Laugharne, R, additional, Ledger, J, additional, Barnes,, T, additional, Jones, C, additional, Osuji, N, additional, Chitalia, N, additional, Bailey, T, additional, Akhtar, S, additional, Harrison, G, additional, Horne, S, additional, Walker, N, additional, Agwuh, K, additional, Maxwell, V, additional, Graves, J, additional, Williams, S, additional, O'Kelly, A, additional, Ridley, P, additional, Cowley, A, additional, Johnstone, H, additional, Swift, P, additional, Democratis, J, additional, Meda, M, additional, Brake, S, additional, Gunn, J, additional, Selassi, A, additional, Hams, S, additional, Irvine, V, additional, Chandrasekaran, B, additional, Forsyth, C, additional, Radmore, J, additional, Thomas, C, additional, Brown, K, additional, Roberts, S, additional, Burns, P, additional, Gajee, K, additional, Lewis, T, additional, Byrne, TM, additional, Sanderson, F, additional, Knight, S, additional, Macnaughton, E, additional, Burton, BJL, additional, Smith, H, additional, Chaudhuri, R, additional, Aeron-Thomas, J, additional, Hollinshead, K, additional, Shorten, RJ, additional, Swan, A, additional, Favager, C, additional, Murira, J, additional, Baillon, S, additional, Hamer, S, additional, Shah, A, additional, Russell, J, additional, Brennan, D, additional, Dave, A, additional, Chawla, A, additional, Westwell, F, additional, Adeboyeku, D, additional, Papineni, P, additional, Pegg, C, additional, Williams, M, additional, Ahmad, S, additional, Horsley, A, additional, Gabriel, C, additional, Pagget, K, additional, Maloney, G, additional, Ashcroft, J, additional, Del Rosario, I, additional, Crosby-Nwaobi, R, additional, Flanagan, D, additional, Dhasmana, D, additional, Fowler, S, additional, Cameron, E, additional, Prentice, L, additional, Sinclair, C, additional, Bateman, V, additional, McLelland-Brooks, K, additional, Ho, A, additional, Murphy, M, additional, Cochrane, A, additional, Gibson, A, additional, Black, K, additional, Tempeton, K, additional, Donaldson, S, additional, Coke, L, additional, Elumogo, N, additional, Elliott, J, additional, Padgett, D, additional, Cross, A, additional, Mirfenderesky, M, additional, Joyce, S, additional, Sinanovic, I, additional, Howard, M, additional, Cowling, P, additional, Brazil, M, additional, Hanna, E, additional, Abdelrazik, A, additional, Brand, S, additional, Sheridan, EA, additional, Wadams, B, additional, Lloyd, A, additional, Mouland, J, additional, Giles, J, additional, Pottinger, G, additional, Coles, H, additional, Joseph, M, additional, Lee, M, additional, Orr, S, additional, Chenoweth, H, additional, Browne, D, additional, Auckland, C, additional, Lear, R, additional, Mahungu, T, additional, Rodger, A, additional, Warren, S, additional, Brooking, D, additional, Pai, S, additional, Druyeh, R, additional, Smith, E, additional, Stone, S, additional, Meisner, S, additional, Delgado, D, additional, Underhill, E, additional, Keen, L, additional, Aga, M, additional, Domingos, P, additional, Gormley, S, additional, Kerrison, C, additional, Birch, S, additional, DeSilva, T, additional, Allsop, L, additional, Ambalkar, S, additional, Beekes, M, additional, Jose, S, additional, Tomlinson, J, additional, Painter, Sharen, additional, Price, C, additional, Pepperell, J, additional, James, K, additional, Trinick, T, additional, Moore, L, additional, Day, J, additional, Boulos, A, additional, Knox, I, additional, Defever, E, additional, McCracken, D, additional, Gray, K, additional, Houston, A, additional, Planche, T, additional, Pritchard Jones, R, additional, Wycherley, Diane, additional, Bennett, S, additional, Marrs, J, additional, Nimako, K, additional, Stewart, B, additional, Bain, SC, additional, Kalakonda, N, additional, Khanduri, S, additional, Ashby, A, additional, Holden, M, additional, Mahabir, N, additional, Harwood, J, additional, Payne, B, additional, Court, K, additional, White, N, additional, Longfellow, R, additional, Hughes, LE, additional, Green, ME, additional, Halkes, M, additional, Mercer, P, additional, Roebuck, A, additional, Wilson-Davies, E, additional, Gallego, L, additional, Lazarus, R, additional, Aldridge, N, additional, Berry, L, additional, Game, F, additional, Reynolds, T, additional, Holmes, C, additional, Wiselka, M, additional, Higham, A, additional, Booth, M, additional, Duff, C, additional, Alderton, J, additional, Hilton, D, additional, Powell, J, additional, Jackson, A, additional, Plant, AJ, additional, Ahmed, N, additional, Chin, T, additional, Qazzafi, MZ, additional, Moody, AM, additional, Tilley, RE, additional, Donaghy, T, additional, O'Kane, M, additional, Shipman, K, additional, Sierra, R, additional, Parmar, C, additional, Mills, G, additional, Harvey, D, additional, Huang, YWJ, additional, Birch, J, additional, Robinson, L, additional, Board, S, additional, Broadley, A, additional, Laven, C, additional, Todd, N, additional, Eyre, DW, additional, Jeffery, K, additional, Dunachie, S, additional, Duncan, C, additional, Klenerman, P, additional, Turtle, L, additional, Baxendale, H, additional, and Heeney, JL, additional
Published: 2021
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29. A First Chandra View of the Cool Core Cluster A1668: Offset Cooling and AGN Feedback Cycle

Author: Pasini, T., primary, Gitti, M., additional, Brighenti, F., additional, O’Sullivan, E., additional, Gastaldello, F., additional, Temi, P., additional, and Hamer, S. L., additional
Published: 2021
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30. SARS-CoV-2 infection rates of antibody-positive compared with antibody-negative health-care workers in England: a large, multicentre, prospective cohort study (SIREN)

Author: Hall, Victoria Jane, primary, Foulkes, Sarah, additional, Charlett, Andre, additional, Atti, Ana, additional, Monk, Edward J M, additional, Simmons, Ruth, additional, Wellington, Edgar, additional, Cole, Michelle J, additional, Saei, Ayoub, additional, Oguti, Blanche, additional, Munro, Katie, additional, Wallace, Sarah, additional, Kirwan, Peter D, additional, Shrotri, Madhumita, additional, Vusirikala, Amoolya, additional, Rokadiya, Sakib, additional, Kall, Meaghan, additional, Zambon, Maria, additional, Ramsay, Mary, additional, Brooks, Tim, additional, Brown, Colin S, additional, Chand, Meera A, additional, Hopkins, Susan, additional, Andrews, N, additional, Atti, A, additional, Aziz, H, additional, Brooks, T, additional, Brown, CS, additional, Camero, D, additional, Carr, C, additional, Chand, MA, additional, Charlett, A, additional, Crawford, H, additional, Cole, M, additional, Conneely, J, additional, D'Arcangelo, S, additional, Ellis, J, additional, Evans, S, additional, Foulkes, S, additional, Gillson, N, additional, Gopal, R, additional, Hall, L, additional, Hall, VJ, additional, Harrington, P, additional, Hopkins, S, additional, Hewson, J, additional, Hoschler, K, additional, Ironmonger, D, additional, Islam, J, additional, Kall, M, additional, Karagiannis, I, additional, Kay, O, additional, Khawam, J, additional, King, E, additional, Kirwan, P, additional, Kyffin, R, additional, Lackenby, A, additional, Lattimore, M, additional, Linley, E, additional, Lopez-Bernal, J, additional, Mabey, L, additional, McGregor, R, additional, Miah, S, additional, Monk, EJM, additional, Munro, K, additional, Naheed, Z, additional, Nissr, A, additional, O'Connell, AM, additional, Oguti, B, additional, Okafor, H, additional, Organ, S, additional, Osbourne, J, additional, Otter, A, additional, Patel, M, additional, Platt, S, additional, Pople, D, additional, Potts, K, additional, Ramsay, M, additional, Robotham, J, additional, Rokadiya, S, additional, Rowe, C, additional, Saei, A, additional, Sebbage, G, additional, Semper, A, additional, Shrotri, M, additional, Simmons, R, additional, Soriano, A, additional, Staves, P, additional, Taylor, S, additional, Taylor, A, additional, Tengbe, A, additional, Tonge, S, additional, Vusirikala, A, additional, Wallace, S, additional, Wellington, E, additional, Zambon, M, additional, Corrigan, D, additional, Sartaj, M, additional, Cromey, L, additional, Campbell, S, additional, Braithwaite, K, additional, Price, L, additional, Haahr, L, additional, Stewart, S, additional, Lacey, ED, additional, Partridge, L, additional, Stevens, G, additional, Ellis, Y, additional, Hodgson, H, additional, Norman, C, additional, Larru, B, additional, Mcwilliam, S, additional, Winchester, S, additional, Cieciwa, P, additional, Pai, A, additional, Loughrey, C, additional, Watt, A, additional, Adair, F, additional, Hawkins, A, additional, Grant, A, additional, Temple-Purcell, R, additional, Howard, J, additional, Slawson, N, additional, Subudhi, C, additional, Davies, S, additional, Bexley, A, additional, Penn, R, additional, Wong, N, additional, Boyd, G, additional, Rajgopal, A, additional, Arenas-Pinto, A, additional, Matthews, R, additional, Whileman, A, additional, Laugharne, R, additional, Ledger, J, additional, Barnes, T, additional, Jones, C, additional, Botes, D, additional, Chitalia, N, additional, Akhtar, S, additional, Harrison, G, additional, Horne, S, additional, Walker, N, additional, Agwuh, K, additional, Maxwell, V, additional, Graves, J, additional, Williams, S, additional, O'Kelly, A, additional, Ridley, P, additional, Cowley, A, additional, Johnstone, H, additional, Swift, P, additional, Democratis, J, additional, Meda, M, additional, Callens, C, additional, Beazer, S, additional, Hams, S, additional, Irvine, V, additional, Chandrasekaran, B, additional, Forsyth, C, additional, Radmore, J, additional, Thomas, C, additional, Brown, K, additional, Roberts, S, additional, Burns, P, additional, Gajee, K, additional, Byrne, TM, additional, Sanderson, F, additional, Knight, S, additional, Macnaughton, E, additional, Burton, BJL, additional, Smith, H, additional, Chaudhuri, R, additional, Hollinshead, K, additional, Shorten, RJ, additional, Swan, A, additional, Favager, C, additional, Murira, J, additional, Baillon, S, additional, Hamer, S, additional, Gantert, K, additional, Russell, J, additional, Brennan, D, additional, Dave, A, additional, Chawla, A, additional, Westell, F, additional, Adeboyeku, D, additional, Papineni, P, additional, Pegg, C, additional, Williams, M, additional, Ahmad, S, additional, Ingram, S, additional, Gabriel, C, additional, Pagget, K, additional, Maloney, G, additional, Ashcroft, J, additional, Del Rosario, I, additional, Crosby-Nwaobi, R, additional, Reeks, C, additional, Fowler, S, additional, Prentice, L, additional, Spears, M, additional, McKerron, G, additional, McLelland-Brooks, K, additional, Anderson, J, additional, Donaldson, S, 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Marsh, L, additional, Tazzyman, S, additional, Allsop, L, additional, Ambalkar, S, additional, Beekes, M, additional, Jose, S, additional, Tomlinson, J, additional, Jones, A, additional, Price, C, additional, Pepperell, J, additional, Schultz, M, additional, Day, J, additional, Boulos, A, additional, Defever, E, additional, McCracken, D, additional, Gray, K, additional, Houston, A, additional, Planche, T, additional, Pritchard Jones, R, additional, Wycherley, Diane, additional, Bennett, S, additional, Marrs, J, additional, Nimako, K, additional, Stewart, B, additional, Kalakonda, N, additional, Khanduri, S, additional, Ashby, A, additional, Holden, M, additional, Mahabir, N, additional, Harwood, J, additional, Payne, B, additional, Court, K, additional, Staines, N, additional, Longfellow, R, additional, Green, ME, additional, Hughes, LE, additional, Halkes, M, additional, Mercer, P, additional, Roebuck, A, additional, Wilson-Davies, E, additional, Gallego, L, additional, Lazarus, R, additional, Aldridge, N, additional, Berry, L, additional, Game, F, additional, Reynolds, T, additional, Holmes, C, additional, Wiselka, M, additional, Higham, A, additional, Booth, M, additional, Duff, C, additional, Alderton, J, additional, Jory, H, additional, Virgilio, E, additional, Chin, T, additional, Qazzafi, MZ, additional, Moody, AM, additional, Tilley, R, additional, Donaghy, T, additional, Shipman, K, additional, Sierra, R, additional, Jones, N, additional, Mills, G, additional, Harvey, D, additional, Huang, YWJ, additional, Birch, J, additional, Robinson, L, additional, Board, S, additional, Broadley, A, additional, Laven, C, additional, Todd, N, additional, Eyre, DW, additional, Jeffery, K, additional, Dunachie, S, additional, Duncan, C, additional, Klenerman, P, additional, Turtle, L, additional, De Silva, T, additional, Baxendale, H, additional, and Heeney, JL, additional
Published: 2021
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31. Constraining cold accretion on to supermassive black holes: molecular gas in the cores of eight brightest cluster galaxies revealed by joint CO and CN absorption

Author: Rose, Tom, Edge, A. C., Combes, F., Gaspari, M., Hamer, S., Nesvadba, N., Peck, A. B., Sarazin, C., Tremblay, G. R., Baum, S. A., Bremer, M. N., McNamara, B. R., O'Dea, C., Oonk, J. B. R., Russell, H., Salomé, P., Donahue, M., Fabian, A. C., Ferland, G., Mittal, R., Vantyghem, A., O’Dea, C, Department of Physics, Durham University, Laboratoire d'Etude du Rayonnement et de la Matière en Astrophysique (LERMA), École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine-Centre National de la Recherche Scientifique (CNRS), Chaire Galaxies et cosmologie, Collège de France (CdF (institution)), Galaxies, Etoiles, Physique, Instrumentation (GEPI), Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Netherlands Institute for Radio Astronomy (ASTRON), Laboratoire d'Etude du Rayonnement et de la Matière en Astrophysique (LERMA (UMR_8112)), Sorbonne Université (SU)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL), University of Michigan [Ann Arbor], University of Michigan System, Institute of Astronomy [Cambridge], University of Cambridge [UK] (CAM), Hôpital du Sacré-Cœur, Centre Hospitalier de l'Université de Montréal (CHUM), Université de Montréal (UdeM)-Université de Montréal (UdeM), Joseph Louis LAGRANGE (LAGRANGE), Université Côte d'Azur (UCA)-Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Observatoire de la Côte d'Azur, and COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)
Subjects: Absorption spectroscopy, astro-ph.GA, galaxies: active, FOS: Physical sciences, Astrophysics, Astrophysics::Cosmology and Extragalactic Astrophysics, 01 natural sciences, [PHYS.ASTR.CO]Physics [physics]/Astrophysics [astro-ph]/Cosmology and Extra-Galactic Astrophysics [astro-ph.CO], chemistry.chemical_compound, ISM [radio lines], 0103 physical sciences, clusters: general [galaxies], 010303 astronomy & astrophysics, ComputingMilieux_MISCELLANEOUS, Astrophysics::Galaxy Astrophysics, Physics, radio continuum: galaxies, Supermassive black hole, radio lines: ISM, Number density, Line-of-sight, ISM [galaxies], 010308 nuclear & particles physics, Astronomy and Astrophysics, Astrophysics - Astrophysics of Galaxies, Silicon monoxide, galaxies [radio continuum], Accretion (astrophysics), Galaxy, chemistry, Space and Planetary Science, galaxies: clusters: general, [SDU]Sciences of the Universe [physics], Astrophysics of Galaxies (astro-ph.GA), active [galaxies], [PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph], galaxies: ISM, Carbon monoxide
Abstract: To advance our understanding of the fuelling and feedback processes which power the Universe's most massive black holes, we require a significant increase in our knowledge of the molecular gas which exists in their immediate surroundings. However, the behaviour of this gas is poorly understood due to the difficulties associated with observing it directly. We report on a survey of 18 brightest cluster galaxies lying in cool cores, from which we detect molecular gas in the core regions of eight via carbon monoxide (CO), cyanide (CN) and silicon monoxide (SiO) absorption lines. These absorption lines are produced by cold molecular gas clouds which lie along the line of sight to the bright continuum sources at the galaxy centres. As such, they can be used to determine many properties of the molecular gas which may go on to fuel supermassive black hole accretion and AGN feedback mechanisms. The absorption regions detected have velocities ranging from -45 to 283 km s$^{-1}$ relative to the systemic velocity of the galaxy, and have a bias for motion towards the host supermassive black hole. We find that the CN N = 0 - 1 absorption lines are typically 10 times stronger than those of CO J = 0 - 1. This is due to the higher electric dipole moment of the CN molecule, which enhances its absorption strength. In terms of molecular number density CO remains the more prevalent molecule with a ratio of CO/CN $\sim 10$, similar to that of nearby galaxies. Comparison of CO, CN and HI observations for these systems shows many different combinations of these absorption lines being detected., Comment: Accepted for publication in MNRAS
Published: 2019

32. Molecular gas in CLASH brightest cluster galaxies at z ∼ 0.2 – 0.9

Author: Castignani, G., primary, Pandey-Pommier, M., additional, Hamer, S. L., additional, Combes, F., additional, Salomé, P., additional, Freundlich, J., additional, and Jablonka, P., additional
Published: 2020
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33. A molecular absorption line survey towards the AGN of Hydra-A

Author: Rose, Tom, primary, Edge, A C, additional, Combes, F, additional, Hamer, S, additional, McNamara, B R, additional, Russell, H, additional, Gaspari, M, additional, Salomé, P, additional, Sarazin, C, additional, Tremblay, G R, additional, Baum, S A, additional, Bremer, M N, additional, Donahue, M, additional, Fabian, A C, additional, Ferland, G, additional, Nesvadba, N, additional, O’Dea, C, additional, Oonk, J B R, additional, and Peck, A B, additional
Published: 2020
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34. A BCG with Offset Cooling: Is the AGN Feedback Cycle Broken in A2495?

Author: Pasini, T., primary, Gitti, M., additional, Brighenti, F., additional, Temi, P., additional, Amblard, A., additional, Hamer, S. L., additional, Ettori, S., additional, O’Sullivan, E., additional, and Gastaldello, F., additional
Published: 2019
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35. Dense gas formation and destruction in a simulated Perseus-like galaxy cluster with spin-driven black hole feedback

Author: Beckmann, R. S., primary, Dubois, Y., additional, Guillard, P., additional, Salome, P., additional, Olivares, V., additional, Polles, F., additional, Cadiou, C., additional, Combes, F., additional, Hamer, S., additional, Lehnert, M. D., additional, and Pineau des Forets, G., additional
Published: 2019
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36. Ubiquitous cold and massive filaments in cool core clusters

Author: Olivares, V., primary, Salome, P., additional, Combes, F., additional, Hamer, S., additional, Guillard, P., additional, Lehnert, M. D., additional, Polles, F. L., additional, Beckmann, R. S., additional, Dubois, Y., additional, Donahue, M., additional, Edge, A., additional, Fabian, A. C., additional, McNamara, B., additional, Rose, T., additional, Russell, H. R., additional, Tremblay, G., additional, Vantyghem, A., additional, Canning, R. E. A., additional, Ferland, G., additional, Godard, B., additional, Peirani, S., additional, and Pineau des Forets, G., additional
Published: 2019
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37. Identification of patients with depression following stroke? A cohort study using two methods of detection

Author: Lightbody, C E, Baldwin, R, Gibbon, B, Hamer, S, Leathley, M, Subramanian, G, Sutton, C, and Watkins, C
Published: 2009

38. Identification of symbol digit modality test score extremes in Huntington's disease

Author: Braisch, U, Muche, R, Rothenbacher, D, Landwehrmeyer, GB, Long, JD, Bentivoglio, AR, Biunno, I, Bonelli, RM, Dunnett, SB, Illmann, T, Levey, J, Ramos-Arroyo, M, Nielsen, JE, Paivarinta, M, Sebastian, AR, Tabrizi, SJ, Vandenberghe, W, Uhrova, T, Come, A, Garde, MB, Betz, S, Capodarca, S, Wildson, SC, da Silva, V, Di Renzo, M, Finisterra, M, Genoves, C, Gilling, M, Handley, OJ, Hvalstedt, C, Koppers, K, Lamanna, C, Laura, M, Descals, AM, Monza, D, Mutze, L, Oehmen, M, Padieu, H, Paterski, L, Koivisto, SP, Rindal, B, Roren, N, Sasinkova, P, Seliverstov, Y, Timewell, E, Cubillo, PT, van Walsem, MR, Witjes-Ane, MN, Yudina, E, Zielonka, E, Zinzi, P, Braunwarth, EM, Brugger, F, Buratti, L, Hametner, EM, Hepperger, C, Holas, C, Hotter, A, Hussl, A, Larcher, B, Mahlknecht, P, Muller, C, Pinter, B, Poewe, W, Seppi, K, Sprenger, F, Wenning, G, Dupuis, M, Minet, C, Ribai, P, Van Paemel, D, Verellen-Dumoulin, C, Klempir, J, Majerova, V, Roth, J, Babiloni, B, Debruxelles, S, Duche, C, Goizet, C, Jameau, L, Lafoucriere, D, Spampinato, U, Bachoud-Levi, AC, Boisse, MF, de Langavant, LC, Lemoine, L, Morgado, G, Youssov, K, Annic, A, Barthelemy, R, De Bruycker, C, Cabaret, M, Carette, AS, Carriere, N, Decorte, E, Defebvre, L, Delliaux, M, Delval, A, Depelchin, A, Destee, A, Dewulf-Pasz, N, Dondaine, T, Dugauquier, F, Dujardin, K, Lemaire, MH, Manouvrier, S, Peter, M, Plomhause, L, Sablonniere, B, Simonin, C, Tard, C, Thibault-Tanchou, S, Vuillaume, I, Bellonet, M, Benoit, A, Blin, S, Courtin, F, Duru, C, Fasquel, V, Godefroy, O, Krystkowiak, P, Mantaux, B, Roussel, M, Tir, M, Schuler, B, Wannepain, S, Azulay, JP, Chabot, C, Delfini, M, Eusebio, A, Fluchere, F, Grosjean, H, Mundler, L, Nowak, M, Bioux, S, Bliaux, E, Girard, C, Guyant-Marechal, L, Hannequin, D, Hannier, V, Jourdain, S, Maltete, D, Pouliquen, D, Blondeau, L, Calvas, F, Cheriet, S, Delabaere, H, Demonet, JF, Pariente, J, Pierre, M, Beuth, M, Gelderblom, H, Priller, J, Pruss, H, Spruth, E, Thiel, S, Ellrichmannberlin, G, Herrmann, L, Hoffmann, R, Kaminski, B, Saft, C, Bosredon, C, Hunger, U, Lohle, M, Maass, A, Ossig, C, Schmidt, S, Storch, A, Wolz, A, Wolz, M, Kohl, Z, Kozay, C, Ullah, J, Winkler, J, Bergmann, U, Boringer, R, Capetian, P, Kammel, G, Lambeck, J, Meier, S, Rijntjes, M, Zucker, B, Boelmans, K, Ganos, C, Goerendt, I, Heinicke, W, Hidding, U, Munchau, A, Schmalfeld, J, Stubbe, L, Zittel, S, Diercks, G, Dressler, D, Francis, F, Gayde-Stephan, S, Gorzolla, H, Kramer, B, Minschke, R, Schrader, C, Tacik, P, Longinus, B, Lusebrink, A, Muhlau, M, Peinemann, A, Stadtler, M, Weindl, A, Winkelmann, J, Ziegler, C, Bechtel, N, Beckmann, H, Bohlen, S, Gopfert, N, Holzner, E, Lange, H, Reilmann, R, Rohm, S, Rumpf, S, Sass, C, Schepers, S, Weber, N, Barth, K, Buck, A, Connemann, J, Ecker, D, Geitner, C, Held, C, Kesse, A, Landwehrmeyer, B, Lezius, F, Lewerenz, J, Nepper, S, Niess, A, Orth, M, Schneider, A, Schwenk, D, Sussmuth, S, Trautmann, S, Weydt, P, Klebe, S, Musacchio, T, Leypold, C, Noth, K, Cormio, C, de Tommaso, M, Franco, G, Sciruicchio, V, Serpino, C, Calandra-Buonaura, G, Capellari, S, Cortelli, P, Gallassi, R, Poda, R, Sambati, L, Scaglione, C, Maserati, MS, Agosti, C, Barlati, S, Compostella, S, Marchina, E, Padovani, A, Bertini, E, Ghelli, E, Ginestroni, A, Mechi, C, Paganini, M, Piacentini, S, Pradella, S, Romoli, AM, Sorbi, S, Abbruzzese, G, di Poggio, MB, Ferrandes, G, Mandich, P, Marchese, R, Tamburini, T, Baake, V, van den Bogaard, SJA, Bos, R, Dumas, EM, t'Hart, EP, Kampstra, A, Roos, RAC, Schoonderbeek, A, Aaserud, O, Bjorgo, K, Borgeod, N, Dramstad, E, Fannemel, M, Frich, JC, Gorvell, PF, Heiberg, A, Lorentzen, E, Retterstol, L, Rosby, O, Sikiric, A, Stokke, B, van Walsem, M, Wehus, R, Bjornevoll, I, Sando, SB, Haug, MG, Storseth, HH, Arntsen, V, Dziadkiewicz, A, Konkel, A, Narozanska, E, Robowski, P, Sitek, E, Slawek, J, Soltan, W, Szinwelski, M, Arkuszewski, M, Blaszczyk, M, Boczarska-Jedynak, M, Ciach-Wysocka, E, Gorzkowska, A, 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Redondo, L, Sanchez, VS, Fernandez, CM, Mata, MP, Lemos, MDR, Bosca, M, Burguera, JA, Vilaplana, FCBCP, Solis, P, Figuerola, BJ, Palanca, PM, Berglund, P, Constantinescu, R, Fredlund, G, Hosterey-Ugander, U, Linnsand, P, Neleborn-Lingefjard, L, Wahlstrom, J, Palhagen, S, Svenningsson, P, Paucar, M, Wallden, T, Ekwall, C, Goller, ML, Sundblom, J, Stebler, Y, Kaelin, A, Romero, I, Schupbach, M, Zaugg, SW, Jung, H, Petersen, J, Auer, M, Mihaylova, V, Vernon, N, Akhtar, S, Crooks, J, Curtis, A, de Souza, J, Piedad, J, Rickards, H, Wright, J, Pallett, A, Coulthard, E, Gethin, L, Hayward, B, Sieradzan, K, Wright, A, Busse, M, Butcher, C, Dunnett, S, Clenaghan, C, Hunt, S, Jones, L, Jones, U, Khalil, H, Minster, S, Owen, M, Price, K, Townhill, J, Rosser, A, Edwards, M, Ho, C, McGill, M, Porteous, M, Pearson, P, Harrower, T, Irvine, S, Brockie, P, Foster, J, Johns, N, McKenzie, S, Rothery, J, Thomas, G, Yates, S, Deith, C, Ireland, J, Ritchie, S, Andrew, A, Frost, J, Noad, R, Cosgrove, J, Gallantree, D, Hamer, S, Hobson, E, Jamieson, S, Kraus, A, Longthorpe, M, Markova, I, Musgrave, H, Peacy, C, Raman, A, Rowett, L, Toscano, J, Wild, S, Yardumian, P, Clayton, C, Dipple, H, Freire-Patino, D, Hallam, C, Middleton, J, Alusi, S, Davies, R, Foy, K, Gerrans, E, Leggett, H, Pate, L, Anjum, U, Coebergh, J, Eddy, C, McEntagart, M, Patton, M, Peterson, M, Rose, S, Andrews, T, Brown, S, Bruno, S, Doherty, K, Golding, C, Haider, S, Hensman, D, Lahiri, N, Lewis, M, Novak, M, Patel, A, Robertson, N, Rosser, E, Tabrizi, S, Taylor, R, Warner, T, Wild, E, Arran, N, Bek, J, Callaghan, J, Craufurd, D, Fullam, R, Howard, L, Huson, S, Johnson, L, Jones, M, Krishnamoorthy, A, Murphy, H, Oughton, E, Partington-Jones, L, Rogers, D, Sollom, A, Snowden, J, Stopford, C, Thompson, J, Tinkler, P, Trender-Gerhard, I, Verstraelen, N, Westmoreland, L, Cass, G, Davidson, L, Davison, J, Fullerton, N, Holmes, K, Komati, S, McDonnell, S, Mohammed, Z, Morgan, K, Savage, L, Singh, B, Wood, J, Chu, E, Knight, C, O'Neill, M, Das Purkayastha, D, Nemeth, AH, Siuda, G, Valentine, R, Dixon, K, Armstrong, R, Harrison, D, Hughes, M, Large, S, Donovan, JO, Palmer, A, Parkinson, A, Soltysiak, B, Timings, L, Williams, J, Burn, J, Weekes, R, Craven, J, Bailey, W, Coleman, C, Haig-Brown, D, Simpson, S, Hare, M, Majeed, T, Bandmann, O, Bradbury, A, Fairtlough, H, Fillingham, K, Foustanos, I, Gill, P, Kazoka, M, Nevitt, L, Peppa, N, Quarrell, O, Taylor, C, Tidswell, K, O'Donovan, K, Agarwal, V, Anderson, M, Gunner, K, Harris, K, Hayward, E, Heywood, M, Keys, L, Kipps, C, MacKinnon, L, Smalley, S, Gowers, L, Powell, K, Bethwaite, P, Edwards, R, Fuller, K, Phillips, M, Tan, L, Burgunder, JM, Lau, PN, Pica, E, Shoulson, I, Gusella, JG, Antonijevic, I, vankammen, D, Foroud, T, Warner, J, Giuliano, J, Vetter, L, Marshall, F, Marder, K, Frucht, S, Moskowitz, C, Clouse, R, Wasserman, P, Shannon, K, Jaglin, J, Jankovic, J, Palao, A, Harrison, M, Singer, C, Quesada, M, Hersch, S, Rosas, D, Tanev, K, Malarick, K, Colcher, A, Sanchez-Ramos, J, Kostyk, S, Paulsen, J, Perlmutter, J, Tabbal, S, Ross, C, Dorsey, R, Nucifora, F, Dubinsky, R, Dubinsky, H, Suchowersky, O, Klimek, ML, Jones, R, Morgan, J, Mohlo, E, Kang, U, Agarwal, P, Factor, S, Jennings, D, Higgins, D, Adams, J, Frank, S, Saint-Hilaire, M, Diggin, M, Furtado, S, Walker, F, O'Neill, C, Quaid, K, LeDoux, M, Raymond, L, Leavitt, B, Decolongon, J, Perlman, S, Peavy, G, Goldstein, J, Kumar, R, McCusker, E, Griffith, J, Loy, C, Wheelock, V, Tempkin, T, Martin, A, Nance, M, Mallonee, W, Suter, G, Revilla, F, Gartner, M, Drazinic, C, Fitzpatrick, MJ, Panisset, M, Duff, K, Scott, B, Weiner, W, Robottom, B, Chiu, E, Yastrubetskaya, O, Churchyard, A, Greenamyre, TJ, Oakes, D, Beck, C, Robertson, S, Eaton, K, Lindsay, P, Deuel, L, MacDonald, M, Hickey, C, Muratori, L, Leserman, A, Doucette, N, Uc, E, Rodnitzky, R, Vik, S, Davis, R, Dietrich, S, Segro, V, Erickson, D, Hunt, V, Lucarelli, N, Broyles, J, Delarosa, J, Louis, E, Panegyres, P, Schmidt, A, Barton, S, Sperin, E, Testa, C, Thiede, F, Zauber, SE, McInnis, R, Welsh, C, Wesson, M, Coleman, A, and European Commission
Subjects: Adult, Male, congenital, hereditary, and neonatal diseases and abnormalities, COHORT, Cox hazard model, quantile regression, REGISTRY, symbol digit modalities test, Genotype, Neuropsychological Tests, Cohort Studies, 03 medical and health sciences, Cellular and Molecular Neuroscience, Cognition, 0302 clinical medicine, Huntington's disease, Rating scale, mental disorders, medicine, Humans, Verbal fluency test, Longitudinal Studies, Genetics (clinical), Proportional Hazards Models, 030304 developmental biology, 0303 health sciences, Proportional hazards model, business.industry, Reproducibility of Results, Middle Aged, medicine.disease, nervous system diseases, Psychiatry and Mental health, Huntington Disease, Phenotype, Test score, Cohort, Disease Progression, Female, Observational study, business, 030217 neurology & neurosurgery, Stroop effect, Clinical psychology
Abstract: REGISTRY Investigators of the European Huntington's Disease Network and COHORT Investigators of the Huntington Study Group., Studying individuals with extreme phenotypes could facilitate the understanding of disease modification by genetic or environmental factors. Our aim was to identify Huntington's disease (HD) patients with extreme symbol digit modality test (SDMT) scores. We first examined in HD the contribution of cognitive measures of the Unified Huntington's Disease Rating Scale (UHDRS) in predicting clinical endpoints. The language-independent SDMT was used to identify patients performing very well or very poorly relative to their CAG and age cohort. We used data from REGISTRY and COHORT observational study participants (5,603 HD participants with CAG repeats above 39 with 13,868 visits) and of 1,006 healthy volunteers (with 2,241 visits), included to identify natural aging and education effects on cognitive measures. Separate Cox proportional hazards models with CAG, age at study entry, education, sex, UHDRS total motor score and cognitive (SDMT, verbal fluency, Stroop tests) scores as covariates were used to predict clinical endpoints. Quantile regression for longitudinal language-independent SDMT data was used for boundary (2.5% and 97.5% quantiles) estimation and extreme score analyses stratified by age, education, and CAG repeat length. Ten percent of HD participants had an extreme SDMT phenotype for at least one visit. In contrast, only about 3% of participants were consistent SDMT extremes at two or more visits. The thresholds for the one-visit and two-visit extremes can be used to classify existing and new individuals. The identification of these phenotype extremes can be useful in the search for disease modifiers., This work was in part funded by a grant from the EuropeanCommission under the 7th framework programme (RD-Connect, grantagreement number 305444).
Published: 2019

39. Deep and narrow CO absorption revealing molecular clouds in the Hydra-A brightest cluster galaxy

Author: Rose, Tom, primary, Edge, A C, additional, Combes, F, additional, Gaspari, M, additional, Hamer, S, additional, Nesvadba, N, additional, Russell, H, additional, Tremblay, G R, additional, Baum, S A, additional, O’Dea, C, additional, Peck, A B, additional, Sarazin, C, additional, Vantyghem, A, additional, Bremer, M, additional, Donahue, M, additional, Fabian, A C, additional, Ferland, G, additional, McNamara, B R, additional, Mittal, R, additional, Oonk, J B R, additional, Salomé, P, additional, Swinbank, A M, additional, and Voit, M, additional
Published: 2019
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40. The relationship between colour vision loss, contrast sensitivity loss and aging

Author: Vaegan, A., primary, Banks, A., additional, Gathy, A., additional, Hamer, S., additional, Phonesouk, S., additional, Perry, S., additional, and Capon, M., additional
Published: 1993
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41. Discovery of a diffuse optical line emitting halo in the core of the Centaurus cluster of galaxies: line emission outside the protection of the filaments

Author: Hamer, S L, primary, Fabian, A C, additional, Russell, H R, additional, Salomé, P, additional, Combes, F, additional, Olivares, V, additional, Polles, F L, additional, Edge, A C, additional, and Beckmann, R S, additional
Published: 2018
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42. A Galaxy-scale Fountain of Cold Molecular Gas Pumped by a Black Hole

Author: Tremblay, G. R., primary, Combes, F., additional, Oonk, J. B. R., additional, Russell, H. R., additional, McDonald, M. A., additional, Gaspari, M., additional, Husemann, B., additional, Nulsen, P. E. J., additional, McNamara, B. R., additional, Hamer, S. L., additional, O’Dea, C. P., additional, Baum, S. A., additional, Davis, T. A., additional, Donahue, M., additional, Voit, G. M., additional, Edge, A. C., additional, Blanton, E. L., additional, Bremer, M. N., additional, Bulbul, E., additional, Clarke, T. E., additional, David, L. P., additional, Edwards, L. O. V., additional, Eggerman, D., additional, Fabian, A. C., additional, Forman, W., additional, Jones, C., additional, Kerman, N., additional, Kraft, R. P., additional, Li, Y., additional, Powell, M., additional, Randall, S. W., additional, Salomé, P., additional, Simionescu, A., additional, Su, Y., additional, Sun, M., additional, Urry, C. M., additional, Vantyghem, A. N., additional, Wilkes, B. J., additional, and ZuHone, J. A., additional
Published: 2018
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43. Inefficient jet-induced star formation in Centaurus A

Author: Salomé, Q., primary, Salomé, P., additional, Miville-Deschênes, M.-A., additional, Combes, F., additional, and Hamer, S., additional
Published: 2018
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44. Revealing the velocity structure of the filamentary nebula in NGC 1275 in its entirety

Author: Gendron-Marsolais, M, primary, Hlavacek-Larrondo, J, additional, Martin, T B, additional, Drissen, L, additional, McDonald, M, additional, Fabian, A C, additional, Edge, A C, additional, Hamer, S L, additional, McNamara, B, additional, and Morrison, G, additional
Published: 2018
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45. Suicidal ideation in a European Huntington's disease population

Author: Hubers, Aa, van Duijn, E, Roos, Ra, Craufurd, D, Rickards, H, Bernhard Landwehrmeyer, G, van der Mast RC, Giltay, Ej, Bachoud Lévi AC, Bentivoglio, Ar, Biunno, I, Bonelli, Rm, Burgunder, Jm, Dunnett, Sb, Ferreira, Jj, Handley, Oj, Heiberg, A, Llmann, Ti, Landwehrmeyer, Gb, Levey, J, Ramos Arroyo MA, Nielsen, Je, Prokoivisto, S, Päivärinta, M, Rojo Sebastián, A, Tabrizi, Sj, Vandenberghe, W, Verellen Dumoulin, C, Zaremba, J, Uhrova, T, Wahlström, J, Barth, K, Correia Guedes, L, Finisterra, Am, Garde, Mb, Bos, R, Betz, S, Callaghan, J, Fullam, R, Ecker, D, Nielsen, Mg, Hvalstedt, C, Held, C, Koppers, K, Laurà, M, Horta, Sm, Descals, Am, Mestre, T, Minster, S, Monza, D, Mütze, L, Oehmen, M, Townhill, J, Orth, M, Padieu, H, Paterski, L, Peppa, N, Pro Koivisto, S, Roedig, V, Rialland, A, Røren, N, Šašinková, P, Seliverstov, Y, Cubillo, Pt, Walsem, Mr, Wright, A, da Silva WV, Witjes Ané MN, Yudina, E, Zielonka, D, Zielonka, E, Zinzi, P, Herranhof, B, Holl, A, Kapfhammer, Hp, Koppitz, M, Magnet, M, Otti, D, Painold, A, Reisinger, K, Scheibl, M, Hecht, K, Lilek, S, Müller, N, Schöggl, H, Ullah, J, Brugger, F, Hepperger, C, Hotter, A, Seppi, K, Wenning, G, Buratti, L, Hametner, Em, Holas, C, Hussl, A, Poewe, W, Braunwarth, Em, Sprenger, F, Müller, C, Sinadinosa, D, Walleczek, Am, Ladurner, G, Staffen, W, Flamez, A, Morez, V, de Raedt, S, Boogaerts, A, van Reijen, D, Klempíř, J, Majerová, V, Roth, J, Hartikainen, P, Hiivola, H, Martikainen, K, Tuuha, K, Ignatius, J, Kärppä, M, Åman, J, Mustonen, A, Kajula, O, Santala, M, Allain, P, Guérid, Ma, Gohier, B, Olivier, A, Prundean, A, Scherer Gagou, C, Verny, C, Bost, M, Babiloni, B, Debruxelles, S, Duché, C, Goizet, C, Lafoucrière, D, Jameau, L, Spampinato, U, De Bruycker, C, Cabaret, M, Carette, As, Defebvre, L, Decorte, E, Delval, A, Delliaux, M, Destee, A, Dujardin, K, Peter, M, Plomhouse, L, Sablonnière, B, Simonin, C, Lemaire, Mh, Manouvrier, S, Thibault Tanchou, S, Vuillaume, I, Krystkowiak, P, Duru, C, Roussel, M, Wannepain, S, Berrissoul, H, Bellonet, M, Courtin, F, Mantaux, B, Fasquel, V, Godefroy, O, Azulay, Jp, Fluchère, F, Delfini, M, Eusebio, A, Mundler, L, Longato, N, Rudolf, G, Steinmetz, G, Tranchant, C, Wagner, C, Zimmermann, M, Marcel, C, Calvas, F, Pariente, J, Démonet, Jf, Cheriet, S, Kosinski, Cm, Milkereit, E, Probst, D, Reetz, K, Sass, C, Schiefer, J, Schlangen, C, Werner, Cj, Gelderblom, H, Priller, J, Prüß, H, Spruth, Ej, Andrich, J, Ellrichmann, G, Hoffmann, R, Kaminski, B, Saft, C, Stamm, C, Lange, H, Bosredon, C, Maass, A, Schmidt, S, Storch, A, Wolz, M, Kohl, Z, Winkler, J, Capetian, P, Lambeck, J, Zucker, B, Boelmans, K, Ganos, C, Goerendt, I, Hidding, U, Lewerenz, J, Münchau, A, Schmalfeld, J, Stubbe, L, Zittel, S, Diercks, G, Dressler, D, Gorzolla, H, Schrader, C, Tacik, P, Heinicke, W, Longinus, B, Bürk, K, Möller, Jc, Rissling, I, Mühlau, M, Peinemann, A, Städtler, M, Weindl, A, Winkelmann, J, Ziegler, C, Bohlen, S, Hölzner, E, Reilmann, R, Dose, M, Leythaeuser, G, Marquard, R, Raab, T, Schrenk, C, Schuierer, M, Buck, A, Connemann, J, Eschenbach, C, Landwehrmeyer, B, Lezius, F, Nepper, S, Niess, A, Schwenk, D, Süßmuth, S, Trautmann, S, Weydt, P, Cormio, C, Sciruicchio, V, Serpino, C, Tommaso, M, Capellari, S, Cortelli, P, Gallassi, R, Poda, R, Rizzo, G, Scaglione, C, Bertini, E, Ghelli, E, Ginestroni, A, Massaro, F, Mechi, C, Paganini, M, Piacentini, S, Pradella, S, Romoli, Am, Sorbi, S, Abbruzzese, G, di Poggio MB, Di Maria, E, Ferrandes, G, Mandich, P, Marchese, R, Albanese, A, Di Bella, D, Di Donato, S, Gellera, C, Genitrini, S, Mariotti, C, Nanetti, L, Paridi, D, Soliveri, P, Tomasello, C, De Michele, G, Di Maio, L, Salvatore, E, Rinaldi, C, Rossi, F, Massarelli, M, Roca, A, Ammendola, S, Russo, Cv, Squitieri, F, Elifani, F, Maglione, V, Di Pardo, A, Alberti, S, Griguoli, A, Amico, E, Martino, T, Petrollini, M, Catalli, C, Di Giacopo, R, Fasano, A, Frontali, M, Guidubaldi, A, Ialongo, T, Jacopini, G, Loria, G, Piano, C, Chiara, P, Quaranta, D, Romano, Silvia, Soleti, F, Spadaro, M, Romano, S, van Hout MS, van Vugt JP, Weert, A, Bolwijn, J, Dekker, M, Leenders, K, Kremer, Hp, Dumas, Em, van den Bogaard SJ, 't Hart EP, Økland, E, Hauge, E, Tyvoll, H, Frich, J, Aaserud, O, Wehus, R, Bjørgo, K, Fannemel, M, Gørvell, P, Lorentzen, E, Koivisto, Sp, Retterstøl, L, Overland, T, Stokke, B, Sando, B, Dziadkiewicz, A, Nowak, M, Robowski, P, Sitek, E, Slawek, J, Soltan, W, Szinwelski, M, Blaszcyk, M, Boczarska Jedynak, M, Ciach Wysocka, E, Gorzkowska, A, Jasinska Myga, B, Opala, G, Kłodowska Duda, G, Stompel, D, Banaszkiewicz, K, Boćwińska, D, Szczudlik, A, Rudzińska, M, Wójcik, M, Dec, M, Krawczyk, M, Jaremek, Kb, Szczygieł, E, Stenwak, A, Ielewska, Aw, Bryl, A, Ciesielska, A, Klimberg, A, Marcinkowski, J, Sempołowicz, J, Samara, H, Wiśniewski, B, Janik, P, Gogol, A, Kwiecinski, H, Jamrozik, Z, Kaminska, A, Antczak, J, Jachinska, K, Rakowicz, M, Richter, P, Rola, R, Ryglewicz, D, Sienkiewicz Jarosz, H, Stępniak, I, Witkowski, G, 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García, Ss, Riballo, Av, González, Sg, Guisasola, Lm, Salvador, C, San Martín ES, González, M, Gorospe, A, Legarda, I, Arques, Pn, Torres Rodríguez MJ, Vives, B, Gaston, I, Martinez Jaurrieta MD, Manuel, J, Moreno, G, Peña, Jc, Avarvarei, Ld, Bastida, Am, Recio, Mf, Vergé, Lr, Sánchez, Vs, Carrillo, F, Cáceres, Mt, Mir, P, Suarez, Mj, Bosca, M, Burguera, Ja, Garcia, Ac, Brugada, Fc, Martínez, Lm, Val, Jl, Loutfi, G, Olofsson, C, Stattin, El, Westman, L, Wikström, B, Lhagen, Se, Paucar, M, Svenningsson, P, Reza Soltani TW, Höglund, A, Sandström, B, Høsterey Ugander, U, Fredlund, G, Constantinescu, R, Neleborn Lingefjärd, L, Tedr off, J, Esmaeilzadeh, M, Winnberg, E, Pålhagen, S, Svennigsson, P, Riza Soltani TW, Sundblom, J, Johansson, A, Wiklund, L, Ekwall, C, Göller, Ml, Petersén, A, Reimer, J, Widner, H, Stebler, Y, Kaelin, A, Romero, I, Schüpbach, M, Weber, S, Miedzybrodzka, Z, Rae, D, Downie, L, Simpson, S, Summers, F, Ure, A, Jack, R, Matheson, K, Akhtar, S, Crooks, J, Curtis, A, Souza, J, Wright, J, Hayward, B, Sieradzan, K, Barker, Ra, O'Keefe, D, Di Pietro, A, Fisher, K, Hill, S, Mason, S, Swain, R, Valle, N, Guzman, Bisson, J, Busse, M, Butcher, C, Clenaghan, C, Dunnett, S, Handley, O, Hunt, S, Hughes, A, Johnstone, C, Jones, L, Jones, U, Khalil, H, Owen, M, Price, K, Rose, Le, Rosser, A, Porteous, M, Edwards, M, Ho, C, Mcgill, M, Pearson, P, Brockie, P, Foster, J, Johns, N, Mckenzie, S, Rothery, J, Thomas, G, Yates, S, Miller, J, Ritchie, S, Burrows, L, Fletcher, A, Harding, A, Laver, F, Silva, M, Thomson, A, Rowett, L, Gallantrae, D, Longthorpe, M, Markova, I, Raman, A, Hamer, S, Wild, S, Yarduiman, P, Chu, C, Kraus, A, Yardumian, P, Musgrave, H, Toscano, J, Jamieson, S, Hobson, E, Clayton, C, Dipple, H, Middleton, J, Freire Patino, D, Andrews, T, Dougherty, A, Kavalier, F, Golding, C, Laing, H, Lashwood, A, Robertson, D, Ruddy, D, Whaite, A, Santhouse, A, Patton, M, Peterson, M, Rose, S, Bruno, S, Chu, E, Doherty, K, Haider, S, Hensman, D, Lahiri, N, Lewis, M, Novak, M, Patel, A, Robertson, N, Rosser, E, Tabrizi, S, Taylor, R, Warner, T, Wild, E, Howard, L, Sollom, A, Snowden, J, Thompson, J, Jones, M, Murphy, H, Trender Gerhard, I, Rogers, D, Bek, J, Oughton, E, Johnson, L, Hare, M, Arran, N, Verstraelen, N, Partington Jones, L, Huson, S, Stopford, C, Westmoreland, L, Davidson, J, Morgan, K, Savage, L, Singh, B, Komati, S, Nemeth, Ah, Armstrong, R, Valentine, R, Siuda, G, Harrison, D, Hughes, M, Parkinson, A, Soltysiak, B, Burn, J, Coleman, C, Bandmann, O, Bradbury, A, Gill, P, Fairtlough, H, Fillingham, K, Foustanos, I, Kazoka, M, O'Donovan, K, Taylor, C, Tidswell, K, Quarrell, O., Laboratoire de Psychologie des Pays de la Loire (LPPL), Université d'Angers (UA)-Université de Nantes - UFR Lettres et Langages (UFRLL), Université de Nantes (UN)-Université de Nantes (UN), A. A., M, E. v., Duijn, R. A., C, D., Craufurd, H., Rickard, G. B., Landwehrmeyer, R. C., Van, E. J., Giltay, R. E., G., Rinaldi, Carlo, Anna A.M. Huber, Erik van Duijn, Raymund A.C. Roo, David Craufurd, Hugh Rickard, G. Bernhard Landwehrmeyer, Rose C. van der Mast, Erik J. Giltay REGISTRY investigators of the European Huntington's Disease Network. Collaborators: Bachoud-Lévi AC, Bentivoglio AR, Biunno I, Bonelli RM, Burgunder JM, Dunnett SB, Ferreira JJ, Handley OJ, Heiberg A, llmann TI, Landwehrmeyer GB, Levey J, Ramos-Arroyo MA, Nielsen JE, ProKoivisto S, Päivärinta M, Roos RA, Rojo Sebastián A, Tabrizi SJ, Vandenberghe W, Verellen- Dumoulin C, Zaremba J, Uhrova T, Wahlström J, Barth K, Correia-Guedes L, Finisterra AM, Garde MB, Bos R, Betz S, Callaghan J, Fullam R, Ecker D, Nielsen MG, Hvalstedt C, Held C, Koppers K, Laurà M, Horta SM, Descals AM, Mestre T, Minster S, Monza D, Mütze L, Oehmen M, Townhill J, Orth M, Padieu H, Paterski L, Peppa N, Pro Koivisto S, Roedig V, Rialland A, Røren N, Šašinková P, Seliverstov Y, Cubillo PT, Walsem MR, Wright A, da Silva WV, Witjes-Ané MN, Yudina E, Zielonka D, Zielonka E, Zinzi P, Herranhof B, Holl A, Kapfhammer HP, Koppitz M, Magnet M, Otti D, Painold A, Reisinger K, Scheibl M, Hecht K, Lilek S, Müller N, Schöggl H, Ullah J, Brugger F, Hepperger C, Hotter A, Seppi K, Wenning G, Buratti L, Hametner EM, Holas C, Hussl A, Poewe W, Braunwarth EM, Sprenger F, Müller C, Sinadinosa D, Walleczek AM, Ladurner G, Staffen W, Flamez A, Morez V, de Raedt S, Boogaerts A, van Reijen D, Klempíř J, Majerová V, Roth J, Hartikainen P, Hiivola H, Martikainen K, Tuuha K, Ignatius J, Kärppä M, Åman J, Mustonen A, Kajula O, Santala M, Allain P, Guérid MA, Gohier B, Olivier A, Prundean A, Scherer- Gagou C, Verny C, Bost M, Babiloni B, Debruxelles S, Duché C, Goizet C, Lafoucrière D, Jameau L, Spampinato U, De Bruycker C, Cabaret M, Carette AS, Defebvre L, Decorte E, Delval A, Delliaux M, Destee A, Dujardin K, Peter M, Plomhouse L, Sablonnière B, Simonin C, Lemaire MH, Manouvrier S, Thibault-Tanchou S, Vuillaume I, Krystkowiak P, Duru C, Roussel M, Wannepain S, Berrissoul H, Bellonet M, Courtin F, Mantaux B, Fasquel V, Godefroy O, Azulay JP, Fluchère F, Delfini M, Eusebio A, Mundler L, Longato N, Rudolf G, Steinmetz G, Tranchant C, Wagner C, Zimmermann M, Marcel C, Calvas F, Pariente J, Démonet JF, Cheriet S, Kosinski CM, Milkereit E, Probst D, Reetz K, Sass C, Schiefer J, Schlangen C, Werner CJ, Gelderblom H, Priller J, Prüß H, Spruth EJ, Andrich J, Ellrichmann G, Hoffmann R, Kaminski B, Saft C, Stamm C, Lange H, Bosredon C, Maass A, Schmidt S, Storch A, Wolz M, Kohl Z, Winkler J, Capetian P, Lambeck J, Zucker B, Boelmans K, Ganos C, Goerendt I, Hidding U, Lewerenz J, Münchau A, Schmalfeld J, Stubbe L, Zittel S, Diercks G, Dressler D, Gorzolla H, Schrader C, Tacik P, Heinicke W, Longinus B, Bürk K, Möller JC, Rissling I, Mühlau M, Peinemann A, Städtler M, Weindl A, Winkelmann J, Ziegler C, Bohlen S, Hölzner E, Reilmann R, Dose M, Leythaeuser G, Marquard R, Raab T, Schrenk C, Schuierer M, Buck A, Connemann J, Eschenbach C, Landwehrmeyer B, Lezius F, Nepper S, Niess A, Schwenk D, Süßmuth S, Trautmann S, Weydt P, Cormio C, Sciruicchio V, Serpino C, Tommaso M, Capellari S, Cortelli P, Gallassi R, Poda R, Rizzo G, Scaglione C, Bertini E, Ghelli E, Ginestroni A, Massaro F, Mechi C, Paganini M, Piacentini S, Pradella S, Romoli AM, Sorbi S, Abbruzzese G, di Poggio MB, Di Maria E, Ferrandes G, Mandich P, Marchese R, Albanese A, Di Bella D, Di Donato S, Gellera C, Genitrini S, Mariotti C, Nanetti L, Paridi D, Soliveri P, Tomasello C, De Michele G, Di Maio L, Salvatore E, Rinaldi C, Rossi F, Massarelli M, Roca A, Ammendola S, Russo CV, Squitieri F, Elifani F, Maglione V, Di Pardo A, Alberti S, Griguoli A, Amico E, Martino T, Petrollini M, Catalli C, Di Giacopo R, Fasano A, Frontali M, Guidubaldi A, Ialongo T, Jacopini G, Loria G, Piano C, Chiara P, Quaranta D, Romano S, Soleti F, Spadaro M, van Hout MS, van Vugt JP, Weert A, Bolwijn J, Dekker M, Leenders K, Kremer HP, Dumas EM, van den Bogaard SJ, 't Hart EP, van Duijn E, Økland E, Hauge E, Tyvoll H, Frich J, Aaserud O, Wehus R, Bjørgo K, Fannemel M, Gørvell P, Lorentzen E, Koivisto SP, Retterstøl L, Overland T, Stokke B, Sando B, Dziadkiewicz A, Nowak M, Robowski P, Sitek E, Slawek J, Soltan W, Szinwelski M, Blaszcyk M, Boczarska-Jedynak M, Ciach-Wysocka E, Gorzkowska A, Jasinska-Myga B, Opala G, Kłodowska-Duda G, Stompel D, Banaszkiewicz K, Boćwińska D, Szczudlik A, Rudzińska M, Wójcik M, Dec M, Krawczyk M, Jaremek KB, Szczygieł E, Stenwak A, ielewska AW, Bryl A, Ciesielska A, Klimberg A, Marcinkowski J, Sempołowicz J, Samara H, Wiśniewski B, Janik P, Gogol A, Kwiecinski H, Jamrozik Z, Kaminska A, Antczak J, Jachinska K, Rakowicz M, Richter P, Rola R, Ryglewicz D, Sienkiewicz-Jarosz H, Stępniak I, Witkowski G, Zdzienicka E, Sułek A, Krysa W, Zieora-Jakutowicz K, Júlio F, Januário C, Coelho M, Mendes T, Valadas A, Timóteo Â, Costa C, Cavaco S, Damásio J, Loureiro R, Magalhães M, Andrade C, Gago M, Garrett C, Guerra MR, Lima J, Massano J, Meireles J, Herrera CD, Garcia PM, Barrero F, Morales B, Cubo E, Mariscal N, Sánchez J, Alonso-Frech F, Perez MR, Fenollar M, García RG, Quiroga PP, Rivera SV, Villanueva C, Alegre J, Bascuñana M, Caldentey JG, Ventura MF, Ribas GG, Yébenes JG, López-Sendón Moreno JL, García Ruíz PJ, Martínez-Descals A, Artiga MJ, Sánchez V, Guerrero R, Bárcenas AH, Noguera Perea MF, Fortuna L, Martirio M, Torres A, Reinante G, Moreau LV, Barbera MA, Guia DB, Hernanz LC, Catena JL, Sebastián AR, Ferrer PQ, Carruesco GT, Bas J, Busquets N, Calopa M, Elorza MD, Díez-AjaLópez C, Terol SD, Robert MF, Ruíz BG, Casado AG, Martínez IH, Viladrich CM, Càrdenas RP, Roca E, Llesoy JR, Idiago JM, Vergara MR, García SS, Riballo AV, González SG, Guisasola LM, Salvador C, San Martín ES, González M, Gorospe A, Legarda I, Arques PN, Torres Rodríguez MJ, Vives B, Gaston I, Martinez-Jaurrieta MD, Manuel J, Moreno G, Peña JC, Avarvarei LD, Bastida AM, Recio MF, Vergé LR, Sánchez VS, Carrillo F, Cáceres MT, Mir P, Suarez MJ, Bosca M, Burguera JA, Garcia AC, Brugada FC, Martínez LM, Val JL, Loutfi G, Olofsson C, Stattin EL, Westman L, Wikström B, lhagen SE, Paucar M, Svenningsson P, Reza- Soltani TW, Höglund A, Sandström B, Høsterey-Ugander U, Fredlund G, Constantinescu R, Neleborn-Lingefjärd L, Tedr- off J, Esmaeilzadeh M, Winnberg E, Pålhagen S, Svennigsson P, Riza-Soltani TW, Sundblom J, Johansson A, Wiklund L, Ekwall C, Göller ML, Petersén A, Reimer J, Widner H, Stebler Y, Kaelin A, Romero I, Schüpbach M, Weber S, Miedzybrodzka Z, Rae D, Downie L, Simpson S, Summers F, Ure A, Jack R, Matheson K, Akhtar S, Crooks J, Curtis A, Souza J, Rickards H, Wright J, Hayward B, Sieradzan K, Barker RA, O'Keefe D, Di Pietro A, Fisher K, Hill S, Mason S, Swain R, Valle N, Guzman, Bisson J, Busse M, Butcher C, Clenaghan C, Dunnett S, Handley O, Hunt S, Hughes A, Johnstone C, Jones L, Jones U, Khalil H, Owen M, Price K, Rose LE, Rosser A, Porteous M, Edwards M, Ho C, McGill M, Pearson P, Brockie P, Foster J, Johns N, McKenzie S, Rothery J, Thomas G, Yates S, Miller J, Ritchie S, Burrows L, Fletcher A, Harding A, Laver F, Silva M, Thomson A, Rowett L, Gallantrae D, Longthorpe M, Markova I, Raman A, Hamer S, Wild S, Yarduiman P, Chu C, Kraus A, Yardumian P, Musgrave H, Toscano J, Jamieson S, Hobson E, Clayton C, Dipple H, Middleton J, Freire-Patino D, Andrews T, Dougherty A, Kavalier F, Golding C, Laing H, Lashwood A, Robertson D, Ruddy D, Whaite A, Santhouse A, Patton M, Peterson M, Rose S, Bruno S, Chu E, Doherty K, Haider S, Hensman D, Lahiri N, Lewis M, Novak M, Patel A, Robertson N, Rosser E, Tabrizi S, Taylor R, Warner T, Wild E, Craufurd D, Howard L, Sollom A, Snowden J, Thompson J, Jones M, Murphy H, Trender-Gerhard I, Rogers D, Bek J, Oughton E, Johnson L, Hare M, Arran N, Verstraelen N, Partington-Jones L, Huson S, Stopford C, Westmoreland L, Davidson J, Morgan K, Savage L, Singh B, Komati S, Nemeth AH, Armstrong R, Valentine R, Siuda G, Harrison D, Hughes M, Parkinson A, Soltysiak B, Burn J, Coleman C, Bandmann O, Bradbury A, Gill P, Fairtlough H, Fillingham K, Foustanos I, Kazoka M, O'Donovan K, Taylor C, Tidswell K, Quarrell O., Molecular Neuroscience and Ageing Research (MOLAR), Hubers, Aa, van Duijn, E, Roos, Ra, Craufurd, D, Rickards, H, Bernhard Landwehrmeyer, G, van der Mast, Rc, Giltay, Ej, CollaboratorsBachoud Lévi AC, REGISTRY investigators of the European Huntington's Disease N. e. t. w. o. r. k., Bentivoglio, Ar, Biunno, I, Bonelli, Rm, Burgunder, Jm, Dunnett, Sb, Ferreira, Jj, Handley, Oj, Heiberg, A, Llmann, Ti, Landwehrmeyer, Gb, Levey, J, Ramos Arroyo, Ma, Nielsen, Je, Prokoivisto, S, Päivärinta, M, Rojo Sebastián, A, Tabrizi, Sj, Vandenberghe, W, Verellen Dumoulin, C, Zaremba, J, Uhrova, T, Wahlström, J, Barth, K, Correia Guedes, L, Finisterra, Am, Garde, Mb, Bos, R, Betz, S, Callaghan, J, Fullam, R, Ecker, D, Nielsen, Mg, Hvalstedt, C, Held, C, Koppers, K, Laurà, M, Horta, Sm, Descals, Am, Mestre, T, Minster, S, Monza, D, Mütze, L, Oehmen, M, Townhill, J, Orth, M, Padieu, H, Paterski, L, Peppa, N, Pro Koivisto, S, Roedig, V, Rialland, A, Røren, N, a??inková, P, Seliverstov, Y, Cubillo, Pt, Walsem, Mr, Wright, A, da Silva, Wv, Witjes Ané, Mn, Yudina, E, Zielonka, D, Zielonka, E, Zinzi, P, Herranhof, B, Holl, A, Kapfhammer, Hp, Koppitz, M, Magnet, M, Otti, D, Painold, A, Reisinger, K, Scheibl, M, Hecht, K, Lilek, S, Müller, N, Schöggl, H, Ullah, J, Brugger, F, Hepperger, C, Hotter, A, Seppi, K, Wenning, G, Buratti, L, Hametner, Em, Holas, C, Hussl, A, Poewe, W, Braunwarth, Em, Sprenger, F, Müller, C, Sinadinosa, D, Walleczek, Am, Ladurner, G, Staffen, W, Flamez, A, Morez, V, de Raedt, S, Boogaerts, A, van Reijen, D, Klempí??, J, Majerová, V, Roth, J, Hartikainen, P, Hiivola, H, Martikainen, K, Tuuha, K, Ignatius, J, Kärppä, M, Åman, J, Mustonen, A, Kajula, O, Santala, M, Allain, P, Guérid, Ma, Gohier, B, Olivier, A, Prundean, A, Scherer Gagou, C, Verny, C, Bost, M, Babiloni, B, Debruxelles, S, Duché, C, Goizet, C, Lafoucrière, D, Jameau, L, Spampinato, U, De Bruycker, C, Cabaret, M, Carette, A, Defebvre, L, Decorte, E, Delval, A, Delliaux, M, Destee, A, Dujardin, K, Peter, M, Plomhouse, L, Sablonnière, B, Simonin, C, Lemaire, Mh, Manouvrier, S, Thibault Tanchou, S, Vuillaume, I, Krystkowiak, P, Duru, C, Roussel, M, Wannepain, S, Berrissoul, H, Bellonet, M, Courtin, F, Mantaux, B, Fasquel, V, Godefroy, O, Azulay, Jp, Fluchère, F, Delfini, M, Eusebio, A, Mundler, L, Longato, N, Rudolf, G, Steinmetz, G, Tranchant, C, Wagner, C, Zimmermann, M, Marcel, C, Calvas, F, Pariente, J, Démonet, Jf, Cheriet, S, Kosinski, Cm, Milkereit, E, Probst, D, Reetz, K, Sass, C, Schiefer, J, Schlangen, C, Werner, Cj, Gelderblom, H, Priller, J, Prüß, H, Spruth, Ej, Andrich, J, Ellrichmann, G, Hoffmann, R, Kaminski, B, Saft, C, Stamm, C, Lange, H, Bosredon, C, Maass, A, Schmidt, S, Storch, A, Wolz, M, Kohl, Z, Winkler, J, Capetian, P, Lambeck, J, Zucker, B, Boelmans, K, Ganos, C, Goerendt, I, Hidding, U, Lewerenz, J, Münchau, A, Schmalfeld, J, Stubbe, L, Zittel, S, Diercks, G, Dressler, D, Gorzolla, H, Schrader, C, Tacik, P, Heinicke, W, Longinus, B, Bürk, K, Möller, Jc, Rissling, I, Mühlau, M, Peinemann, A, Städtler, M, Weindl, A, Winkelmann, J, Ziegler, C, Bohlen, S, Hölzner, E, Reilmann, R, Dose, M, Leythaeuser, G, Marquard, R, Raab, T, Schrenk, C, Schuierer, M, Buck, A, Connemann, J, Eschenbach, C, Landwehrmeyer, B, Lezius, F, Nepper, S, Niess, A, Schwenk, D, Süßmuth, S, Trautmann, S, Weydt, P, Cormio, C, Sciruicchio, V, Serpino, C, Tommaso, M, Capellari, S, Cortelli, P, Gallassi, R, Poda, R, Rizzo, G, Scaglione, C, Bertini, E, Ghelli, E, Ginestroni, A, Massaro, F, Mechi, C, Paganini, M, Piacentini, S, Pradella, S, Romoli, Am, Sorbi, S, Abbruzzese, G, di Poggio, Mb, Di Maria, E, Ferrandes, G, Mandich, P, Marchese, R, Albanese, A, Di Bella, D, Di Donato, S, Gellera, C, Genitrini, S, Mariotti, C, Nanetti, L, Paridi, D, Soliveri, P, Tomasello, C, DE MICHELE, Giuseppe, Di Maio, L, Salvatore, Elena, Rossi, F, Massarelli, Marco, Roca, Alessandro, Ammendola, S, Russo, Cinzia, Squitieri, F, Elifani, F, Maglione, V, Di Pardo, A, Alberti, S, Griguoli, A, Amico, E, Martino, T, Petrollini, M, Catalli, C, Di Giacopo, R, Fasano, A, Frontali, M, Guidubaldi, A, Ialongo, T, Jacopini, G, Loria, G, Piano, C, Chiara, P, Quaranta, D, Romano, S, Soleti, F, Spadaro, M, Rinaldi, C, Massarelli, M, Roca, A, Russo, Cv, van Hout, M, van Vugt, Jp, Weert, A, Bolwijn, J, Dekker, M, Leenders, K, Kremer, Hp, Dumas, Em, van den Bogaard, Sj, 't Hart, Ep, Økland, E, Hauge, E, Tyvoll, H, Frich, J, Aaserud, O, Wehus, R, Bjørgo, K, Fannemel, M, Gørvell, P, Lorentzen, E, Koivisto, Sp, Retterstøl, L, Overland, T, Stokke, B, Sando, B, Dziadkiewicz, A, Nowak, M, Robowski, P, Sitek, E, Slawek, J, Soltan, W, Szinwelski, M, Blaszcyk, M, Boczarska Jedynak, M, Ciach Wysocka, E, Gorzkowska, A, Jasinska Myga, B, Opala, G, K??odowska Duda, G, Stompel, D, Banaszkiewicz, K, Bo??wi??ska, D, Szczudlik, A, Rudzi??ska, M, Wójcik, M, Dec, M, Krawczyk, M, Jaremek, Kb, Szczygie??, E, Stenwak, A, Ielewska, Aw, Bryl, A, Ciesielska, A, Klimberg, A, Marcinkowski, J, Sempo??owicz, J, Samara, H, Wi??niewski, B, Janik, P, Gogol, A, Kwiecinski, H, Jamrozik, Z, Kaminska, A, Antczak, J, Jachinska, K, Rakowicz, M, Richter, P, Rola, R, Ryglewicz, D, Sienkiewicz Jarosz, H, St??pniak, I, Witkowski, G, Zdzienicka, E, Su??ek, A, Krysa, W, Zieora Jakutowicz, K, Júlio, F, Januário, C, Coelho, M, Mendes, T, Valadas, A, Timóteo, Â, Costa, C, Cavaco, S, Damásio, J, Loureiro, R, Magalhães, M, Andrade, C, Gago, M, Garrett, C, Guerra, Mr, Lima, J, Massano, J, Meireles, J, Herrera, Cd, Garcia, Pm, Barrero, F, Morales, B, Cubo, E, Mariscal, N, Sánchez, J, Alonso Frech, F, Perez, Mr, Fenollar, M, García, Rg, Quiroga, Pp, Rivera, Sv, Villanueva, C, Alegre, J, Bascuñana, M, Caldentey, Jg, Ventura, Mf, Ribas, Gg, Yébenes, Jg, López Sendón Moreno, Jl, García Ruíz, Pj, Martínez Descals, A, Artiga, Mj, Sánchez, V, Guerrero, R, Bárcenas, Ah, Noguera Perea, Mf, Fortuna, L, Martirio, M, Torres, A, Reinante, G, Moreau, Lv, Barbera, Ma, Guia, Db, Hernanz, Lc, Catena, Jl, Sebastián, Ar, Ferrer, Pq, Carruesco, Gt, Bas, J, Busquets, N, Calopa, M, Elorza, Md, Díez AjaLópez, C, Terol, Sd, Robert, Mf, Ruíz, Bg, Casado, Ag, Martínez, Ih, Viladrich, Cm, Càrdenas, Rp, Roca, E, Llesoy, Jr, Idiago, Jm, Vergara, Mr, García, S, Riballo, Av, González, Sg, Guisasola, Lm, Salvador, C, San Martín, E, González, M, Gorospe, A, Legarda, I, Arques, Pn, Torres Rodríguez, Mj, Vives, B, Gaston, I, Martinez Jaurrieta, Md, Manuel, J, Moreno, G, Peña, Jc, Avarvarei, Ld, Bastida, Am, Recio, Mf, Vergé, Lr, Carrillo, F, Cáceres, Mt, Mir, P, Suarez, Mj, Bosca, M, Burguera, Ja, Garcia, Ac, Brugada, Fc, Martínez, Lm, Val, Jl, Loutfi, G, Olofsson, C, Stattin, El, Westman, L, Wikström, B, Lhagen, Se, Paucar, M, Svenningsson, P, Reza Soltani, Tw, Höglund, A, Sandström, B, Høsterey Ugander, U, Fredlund, G, Constantinescu, R, Neleborn Lingefjärd, L, Tedr off, J, Esmaeilzadeh, M, Winnberg, E, Pålhagen, S, Svennigsson, P, Riza Soltani, Tw, Sundblom, J, Johansson, A, Wiklund, L, Ekwall, C, Göller, Ml, Petersén, A, Reimer, J, Widner, H, Stebler, Y, Kaelin, A, Romero, I, Schüpbach, M, Weber, S, Miedzybrodzka, Z, Rae, D, Downie, L, Simpson, S, Summers, F, Ure, A, Jack, R, Matheson, K, Akhtar, S, Crooks, J, Curtis, A, Souza, J, Wright, J, Hayward, B, Sieradzan, K, Barker, Ra, O'Keefe, D, Di Pietro, A, Fisher, K, Hill, S, Mason, S, Swain, R, Valle, N, Bisson, J, Busse, M, Butcher, C, Clenaghan, C, Dunnett, S, Handley, O, Hunt, S, Hughes, A, Johnstone, C, Jones, L, Jones, U, Khalil, H, Owen, M, Price, K, Rose, Le, Rosser, A, Porteous, M, Edwards, M, Ho, C, Mcgill, M, Pearson, P, Brockie, P, Foster, J, Johns, N, Mckenzie, S, Rothery, J, Thomas, G, Yates, S, Miller, J, Ritchie, S, Burrows, L, Fletcher, A, Harding, A, Laver, F, Silva, M, Thomson, A, Rowett, L, Gallantrae, D, Longthorpe, M, Markova, I, Raman, A, Hamer, S, Wild, S, Yarduiman, P, Chu, C, Kraus, A, Yardumian, P, Musgrave, H, Toscano, J, Jamieson, S, Hobson, E, Clayton, C, Dipple, H, Middleton, J, Freire Patino, D, Andrews, T, Dougherty, A, Kavalier, F, Golding, C, Laing, H, Lashwood, A, Robertson, D, Ruddy, D, Whaite, A, Santhouse, A, Patton, M, Peterson, M, Rose, S, Bruno, S, Chu, E, Doherty, K, Haider, S, Hensman, D, Lahiri, N, Lewis, M, Novak, M, Patel, A, Robertson, N, Rosser, E, Tabrizi, S, Taylor, R, Warner, T, Wild, E, Howard, L, Sollom, A, Snowden, J, Thompson, J, Jones, M, Murphy, H, Trender Gerhard, I, Rogers, D, Bek, J, Oughton, E, Johnson, L, Hare, M, Arran, N, Verstraelen, N, Partington Jones, L, Huson, S, Stopford, C, Westmoreland, L, Davidson, J, Morgan, K, Savage, L, Singh, B, Komati, S, Nemeth, Ah, Armstrong, R, Valentine, R, Siuda, G, Harrison, D, Hughes, M, Parkinson, A, Soltysiak, B, Burn, J, Coleman, C, Bandmann, O, Bradbury, A, Gill, P, Fairtlough, H, Fillingham, K, Foustanos, I, Kazoka, M, O'Donovan, K, Taylor, C, Tidswell, K, and Quarrell, O.
Subjects: Male, medicine.medical_specialty, Heterozygote, Psychopharmacology, Population, Poison control, psychology/statistics /&/ numerical data, Suicide, Attempted, Suicide prevention, Suicidal Ideation, [SHS]Humanities and Social Sciences, 03 medical and health sciences, 0302 clinical medicine, medicine, Prevalence, Humans, epidemiology, Europe, Psychiatry, education, Suicidal ideation, ComputingMilieux_MISCELLANEOUS, Proportional Hazards Models, Attempted, Psychiatric Status Rating Scales, education.field_of_study, Psychological Tests, Suicide attempt, Psychopathology, Depression, Hazard ratio, Huntington's disease, Odds ratio, Middle Aged, 3. Good health, 030227 psychiatry, Europe, psychology, Male, Middle Aged, Prevalence, Proportional Hazards Models, Psychiatric Status Rating Scales, Psychological Tests, Suicidal Ideation, Suicide, Clinical Psychology, Psychiatry and Mental health, Suicide, Huntington Disease, epidemiology, Female, Heterozygote, Humans, Huntington Disease, Cohort studies, Female, medicine.symptom, Psychology, 030217 neurology & neurosurgery, Clinical psychology
Abstract: BACKGROUND: Previous studies indicate increased prevalences of suicidal ideation, suicide attempts, and completed suicide in Huntington's disease (HD) compared with the general population. This study investigates correlates and predictors of suicidal ideation in HD.METHODS: The study cohort consisted of 2106 HD mutation carriers, all participating in the REGISTRY study of the European Huntington's Disease Network. Of the 1937 participants without suicidal ideation at baseline, 945 had one or more follow-up measurements. Participants were assessed for suicidal ideation by the behavioural subscale of the Unified Huntington's Disease Rating Scale (UHDRS). Correlates of suicidal ideation were analyzed using logistic regression analysis and predictors were analyzed using Cox regression analysis.RESULTS: At baseline, 169 (8.0%) mutation carriers endorsed suicidal ideation. Disease duration (odds ratio [OR]=0.96; 95% confidence interval [CI]: 0.9-1.0), anxiety (OR=2.14; 95%CI: 1.4-3.3), aggression (OR=2.41; 95%CI: 1.5-3.8), a previous suicide attempt (OR=3.95; 95%CI: 2.4-6.6), and a depressed mood (OR=13.71; 95%CI: 6.7-28.0) were independently correlated to suicidal ideation at baseline. The 4-year cumulative incidence of suicidal ideation was 9.9%. Longitudinally, the presence of a depressed mood (hazard ratio [HR]=2.05; 95%CI: 1.1-4.0) and use of benzodiazepines (HR=2.44; 95%CI: 1.2-5.0) at baseline were independent predictors of incident suicidal ideation, whereas a previous suicide attempt was not predictive.LIMITATIONS: As suicidal ideation was assessed by only one item, and participants were a selection of all HD mutation carriers, the prevalence of suicidal ideation was likely underestimated.CONCLUSIONS: Suicidal ideation in HD frequently occurs. Assessment of suicidal ideation is a priority in mutation carriers with a depressed mood and in those using benzodiazepines.
Published: 2013

46. Shaken Snow Globes: Kinematic Tracers of the Multiphase Condensation Cascade in Massive Galaxies, Groups, and Clusters

Author: Gaspari, M., primary, McDonald, M., additional, Hamer, S. L., additional, Brighenti, F., additional, Temi, P., additional, Gendron-Marsolais, M., additional, Hlavacek-Larrondo, J., additional, Edge, A. C., additional, Werner, N., additional, Tozzi, P., additional, Sun, M., additional, Stone, J. M., additional, Tremblay, G. R., additional, Hogan, M. T., additional, Eckert, D., additional, Ettori, S., additional, Yu, H., additional, Biffi, V., additional, and Planelles, S., additional
Published: 2018
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47. Ionised gas structure of 100 kpc in an over-dense region of the galaxy group COSMOS-Gr30 at z ~ 0.7

Author: Epinat, B., primary, Contini, T., additional, Finley, H., additional, Boogaard, L. A., additional, Guérou, A., additional, Brinchmann, J., additional, Carton, D., additional, Michel-Dansac, L., additional, Bacon, R., additional, Cantalupo, S., additional, Carollo, M., additional, Hamer, S., additional, Kollatschny, W., additional, Krajnović, D., additional, Marino, R. A., additional, Richard, J., additional, Soucail, G., additional, Weilbacher, P. M., additional, and Wisotzki, L., additional
Published: 2018
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48. Inefficient jet-induced star formation in Centaurus A

Author: Salomé, Q., primary, Salomé, P., additional, Miville-Deschênes, M.-A., additional, Combes, F., additional, and Hamer, S., additional
Published: 2017
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49. The MUSE Hubble Ultra Deep Field Survey

Author: Inami, H., primary, Bacon, R., additional, Brinchmann, J., additional, Richard, J., additional, Contini, T., additional, Conseil, S., additional, Hamer, S., additional, Akhlaghi, M., additional, Bouché, N., additional, Clément, B., additional, Desprez, G., additional, Drake, A. B., additional, Hashimoto, T., additional, Leclercq, F., additional, Maseda, M., additional, Michel-Dansac, L., additional, Paalvast, M., additional, Tresse, L., additional, Ventou, E., additional, Kollatschny, W., additional, Boogaard, L. A., additional, Finley, H., additional, Marino, R. A., additional, Schaye, J., additional, and Wisotzki, L., additional
Published: 2017
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50. FaecalCampylobactershedding among dogs in animal shelters across Texas

Author: Leahy, A. M., primary, Cummings, K. J., additional, Rodriguez-Rivera, L. D., additional, Hamer, S. A., additional, and Lawhon, S. D., additional
Published: 2017
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