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Indonesia adalah salah satu dari negara tropis dunia yang memiliki kekayaan biodiversitas yang sangat tinggi. Salah satu kawasan yang memiliki biodiversitas tinggi dan dijadikan cagar alam adalah Meru Betiri. Kawasan ini tidak hanya terkenal dengan perlindungan terhadap Harimau Jawa, tetapi juga berbagai keindahan panorama alam dan lokasi hutan hujan tropis yang masih terlindung, salah satunya adalah wilayah Bandealit. Penelitian ini bertujuan menentukan jalur strategis yang dapat disarankan sebagai jalur birdwatching di Bandealit. Pengamatan dilakukan selama dua hari, yaitu pada tanggal 16-17 Nopember 2012. Pengamatan dilakukan dengan menjelajahi jalur-jalur yang dinilai berpotensi sebagai lokasi pengembangan birdwatching. Selain itu, juga dilakukan wawancara terhadap orang-orang kunci untuk mengetahui fluktuasi jumlah spesies di kawasan, konfirmasi jenis, serta mencari informasi terkait spesies yang belum dapat ditemukan. Kami telah menentukan tiga jalur yang berpotensi sebagai jalur birdwatching, yaitu Muara Timur (jalur 1), Savana (jalur 2), dan Lintasan Satwa (jalur 3). Jalur 1 tidak direkomendasikan karena kuantitas dan kualitas spesies yang ditemukan tidak terlalu baik. Jalur 2 dan jalur 3 direkomendasikan untuk pengembangan wisata birdwatching di Bandealit. Kata kunci: Bandealit, birdwatching, jalur birdwatching

Colchicine is microtubule inhibiting agent used for thecure of various skin ailments causing inflammation and reduction of pain in gouty arthritis.The current study was designed to evaluate the effect of colchicine on cellular immune responses in mice. Cellular immune responses were assessed indelayed type hypersensitivity (DTH) assay, macrophage engulfment assay, cyclophosphamide induced neutropenic test and nitric oxide (NO) production assay.Colchicine was administered to mice at doses of 40μg/kg, 80μg/kg and 160μg/kg intraperitoneally. Data were statistically analyzed by ANOVA and chi square test. DTH showed significant (P<0.0001) decrease in skin thickness of colchicine treated groups. In macrophage engulfment assay, significant (P<0.0001) decrease in engulfment of sheep red blood cells (SRBCs) was observed by macrophages in colchicine treated groups. Colchicine treated groups showed significant (P<0.0001) reduction of TLC and neutrophil count.NO production difference was significantly (P<0.0001) reduced in macrophages alone and lipopolysaccharide (LPS) stimulated macrophages in colchicine treated groups. Therefore, it is concluded that colchicine suppresses the cellular immune responses in mice. [ABSTRACT FROM AUTHOR]

Background: A strong understanding of infection prevention and control (IPC) procedures and comprehensive training among healthcare workers is essential for effective IPC programs. These elements play a crucial role in breaking the chain of nosocomial infections by preventing the transmission of resistant organisms to patients and staff members. This study mapped the components of IPC education and training across various member states of the World Health Organization (WHO) in the Eastern Mediterranean Region (EMR) at national, academic, and healthcare institutional levels., Methods: A self-administered structured online questionnaire based on the WHO "Core Component 3" of IPC programs at the national and acute healthcare facility levels (IPC education and training) was given to national IPC focal persons in each of the WHO's EMR countries between February and March 2023., Results: From 14 of the 22 countries,15 IPC persons participated in the survey. Most countries have scattered nonhomogeneous IPC education programs in human health undergraduate majors without considering it a standalone module. Academic institutions are rarely involved, and elaborate and predefined undergraduate IPC education programs provided by universities are present in 21.4% of the countries. In 71.4% of these countries, postgraduate training targeting IPC professionals is provided by national IPC teams, primarily based on national IPC guidelines developed with the aid of the WHO. Generally, healthcare worker training relies heavily on healthcare facilities in 92.9% of the countries, rather than on a national training program. In 42.9% of the countries, practicing IPC physicians are not necessarily specialists of infectious disease or medical microbiologists and IPC nurses are not required to specialize in IPC. However, nonspecialized IPC professionals are expected to undergo training upon employment and before beginning practice. Nongovernmental organizations such as the WHO play a significant role in IPC education and in supporting national IPC authorities in establishing national IPC guidelines, as it is the case in 78.6% of these countries., Conclusion: Clear disparities exist in IPC education and training across different countries in the WHO's EMR. Establishing a regional scientific network specializing in IPC would help bridge the existing gaps and standardize this education within individual countries and across countries in the region. This region needs to establish IPC certification standards and standardized education curricula., (© 2023. BioMed Central Ltd., part of Springer Nature.)

One Health is increasingly recognized as an optimal approach to address the global risk of health threats originating at the human, animal, and ecosystem interface, and their impact. Qatar has successfully practiced One Health approach for investigation and surveillance of zoonotic diseases such as MERS-CoV, and other health threats. However, the current gaps at institution and policy level hinder the sustainment of One Health. In this paper, we have assessed the potential for implementation of One Health Framework to reinforce and sustain One Health capacities in Qatar for 2022-2027. To implement One Health Framework in the country, Qatar Joint External Evaluation (JEE) report, lessons learnt during One Health experiences on zoonotic, vector-borne, and food borne diseases were used to present an outline for multisectoral coordination. In addition, technical capacities of One Health and factors that are required to operationalize it in the country were also assessed in series of meetings and workshops held at Ministry of Public Health on March 2022. Present health care infrastructure and resources were found to be conducive for effective management and response to shared health threats as evident during MERS-CoV, despite being more event based. Regardless, the need for more sustainable capacity development was unanimously emphasized. The consensus between all relevant stakeholders and partners was that there is a need for better communication channels, policies and protocols for data sharing, and the need to invest more resources for better sustainability. The proposed framework is expected to strengthen and facilitate multilateral coordination, enhanced laboratory capacity and network, improve active surveillance and response, risk communication, community engagement, maximize applied research, and build One Health technical work force. This would enable advancement and sustainment of One Health activities to prevent and control health threats shared between humans-animals-ecosystem interface., Competing Interests: The authors declare there is no conflict of interest., (© 2023 Published by Elsevier B.V.)

Background: Being the first line of defense against COVID-19 infection, health care workers (HCWs) are at an increased risk of getting infected. Infection prevention and control (IPC) measures were deemed to be instrumental in protecting them and their patients against infection., Purpose: To assess HCWs' knowledge of IPC measures and their perceived effectiveness in protecting against COVID-19., Methods: A national web-based survey was conducted in different health care sectors in Qatar., Results: A total of 1757 HCWs completed the survey. HCWs believed in applying stricter IPC precautions while dealing with confirmed COVID-19 cases than with suspected cases. Males and physicians were more likely to have high perceived effectiveness of IPC measures than females, nurses, and pharmacists. Higher proportions of HCWs believed in the effectiveness of hand hygiene than most types of personal protective equipment., Conclusion: Further research is recommended to assess the impact of HCWs' knowledge and perceived effectiveness of IPC measures on their compliance., Competing Interests: The authors declare no conflict of interest., (Copyright © 2021 The Authors. Published by Wolters Kluwer Health, Inc.)

Aim: To assess health care workers' compliance with infection prevention and control measures in different health care sectors in Qatar during COVID-19 pandemic., Background: Being the first line of defence against COVID-19 infection, health care workers are particularly at increased risk of getting infected. Compliance with infection prevention and control measures is essential for their safety and the safety of patients., Methods: A web-based national survey was conducted between November 2020 and January 2021 targeting all health care workers in governmental, semi-governmental and private health care sectors., Results: Of 1,757 health care workers, 49.9% were between 30 and 39 years of age; the majority (47.5%) were nurses. Participants reported a significant increase in the median self-rated compliance scores during the pandemic compared with before it (p < .001). During the pandemic, 49.7% of health care workers were fully compliant with personal protective equipment (PPE) use; 83.1% were fully compliant with hand hygiene. Overall, 44.1% were fully compliant with infection prevention and control measures (PPE and hand hygiene). Nationality, health sector, profession and frequency of interactions with suspected or confirmed COVID-19 cases were significantly associated with compliance with overall infection prevention and control measures. The most reported barriers were work overload and shortages of PPE and handwashing agents., Conclusions: Compliance of health care workers with infection prevention and control measures needs further improvement., Implications for Nursing Management: Frequent quality checks, provision of adequate supplies and behaviour change interventions are recommended strategies for hospital and nursing administrators to improve health care workers' compliance., (© 2021 The Authors. Journal of Nursing Management published by John Wiley & Sons Ltd.)

The Ministry of Public Health in Qatar developed the NAP (National Action Plan to combat Antimicrobial Resistance (AMR) in collaboration with WHO Regional Office for the Eastern Mediterranean (WHO/EMRO). Among the major factors shaping AMR is antimicrobial prescribing and use. Tailoring Antimicrobial Resistance Program is a behavior change methodology that is utilized to adapt behavior change in relation to antimicrobial use. This study explores barriers of appropriate antibiotic (AB) prescription from the physicians' and pharmacists' perspectives at primary healthcare centers in Qatar. Data were collected from 50 participants across two PHCCs: 30 physicians and 20 pharmacists. Two different interview guides were constructed: One for physicians and one for pharmacists. In-depth, face-to-face, five focus groups were conducted and transcribed verbatim. Inductive qualitative analysis, involving discovering the themes in the interviews, was followed. Data were analyzed using constant comparative techniques. The Major themes arose from the analysis revealed that patients, practitioners mainly physicians, and the organization itself, played a role in shaping these barriers in the two primary healthcare centers. The findings would help develop and pilot behavior change interventions among patients, physicians and pharmacists with the aim of optimizing appropriate antibiotic prescription and use, which would support the implementation of the antibiotic stewardship program. Effective behavior change interventions should consider multiple factors including individual and organizational factors to optimize appropriate antibiotic prescription.