Search

Abstract Sea level rise affects the long-term psychological health of coastal communities. However, research on long-term and seasonal impacts on vulnerable communities’ psychological health is limited. Here, we explore the effect of sea-level rise on the psychological health of the coastal population in Satkhira and Khulna districts of southwest Bangladesh across two seasons: before monsoon (March to April) and post-monsoon months (October to November) in 2021. We leveraged the longitudinal research that involved 1144 participants. We collected data on psychological health using established scales for distress, depression, anxiety, and stress and also measured environmental factors and resource losses. Results indicate that psychological health, particularly distress, depression, anxiety, and stress, increased during the post-monsoon months in communities more vulnerable to sea-level rise. Highly vulnerable communities showed increased psychological distress post-monsoon. Environmental stressors and resource loss escalated during the post-monsoon period, especially in moderate and highly vulnerable communities. Our findings emphasize the urgent need for targeted support and resilience-building interventions in affected communities to alleviate the psychological health impacts of sea-level rise.

Millimeter-wave beamspace massive multiple-input multiple-output system with a lens antenna array can minimize transceiver hardware complexity without compromising performance. However, the number of supported portable user terminals cannot exceed the number of radio frequency blocks accessible at the same time, frequency, and coding resources. In this paper, we propose the integration of rate-splitting multiple access and orthogonal random precoding into the downlink of beamspace massive multiple-input multiple-output system to support a larger number of portable user terminals than the number of available radio frequency blocks while minimizing both inter- and intra-beam interferences and extending the cell coverage percentage. Then, we formulate an optimization problem to optimize the system’s overall throughput while keeping the minimum needed throughput and power budget in consideration. The nonconvex optimization issue is then approximated into a convex optimization problem using the successive convex approximation approach. Following that, we offer an alternating method to solve the approximate optimization issue and select an optimal solution. Furthermore, we deduce an analytic expression for the downlink cell coverage percentage and evaluate the effectiveness of the suggested method in terms of total throughput, energy efficiency, and cell coverage percentage. Finally, we compare the proposed method with benchmark techniques for perfect and imperfect channel state information, and numerical results confirm the superior performance of the proposed method over benchmark techniques in terms of sum throughput, energy efficiency, and cell coverage percentage.

Enhancing Internet of Things (IoT) communications through Reconfigurable Intelligent Surfaces (RIS) necessitates novel approaches that go beyond the conventional deployment of passive elements. This paper introduces an efficient method to enhance IoT system performance by combining active and passive functionality in RISs: an active and passive integrated approach. One identified enhancement area is efficiently managing signal throughput and exchanges in IoT systems, which is essential for supporting numerous devices. For this challenge, we propose a thorough process model that describes channel gains, develops a nonlinear energy harvesting, and identifies device-to-device communication schemes without violating information causality. The innovative component of our work is the utilization and strategic application of RIS panels that benefit from the advantages of active and passive components synergism to solve thermal noise issues and optimize signal reflection and transmission. An advanced optimization mechanism is developed based on mixed-integer nonlinear programming: an enabling approach between performance efficiency and maximum service utilization. Our simulation analysis show that developed RIS panels optimize IoT system performance and surpass existing performance indicators in conventional RIS-less systems.

Understanding the impact of room acoustics on non-native listeners is crucial, particularly in standardized English as a foreign language (EFL) proficiency testing environments. This study aims to elucidate how acoustics influence test scores, considering variables overlooked in prior research such as seat position and baseline language proficiency. In this experiment, 42 Japanese university students’ performance on standardized EFL listening tests was assessed in two rooms with distinct acoustic qualities, as determined by the speech transmission index (STI) and reverberation time (RT). The rooms differed significantly in their STI values and RT measurements, with one exhibiting high speech intelligibility qualities of ≥0.66 STI and RT0.5–2kHz < 0.7 s and the other falling below these benchmarks. The findings revealed that listening test scores were consistently higher in the acoustically favorable room across all participants. Notably, the negative effect of poor acoustics was more pronounced for students with lower baseline language proficiency. No significant score differences were observed between front- and rear-seat positions, suggesting that overall room acoustics may be more influential than individual seating locations. The study concludes that acoustics play a significant role in the standardized EFL test performance, particularly for lower-proficiency learners. This highlights the necessity of standardized testing environments to be more carefully selected in order to ensure the fair and reliable assessment of language proficiency.

Background: According to scientific literature, some 99% of patients affected by Alzheimer’s disease (AD) suffer from behavioral and psychological symptoms of dementia (BPSD), also known as neuropsychiatric symptoms (NPSs). In particular, agitation is one of the most difficult disorders to treat. States of agitation represent a very serious problem as they make these subjects dangerous for themselves and others and worsen as the disease advances. To date, there are no specific solutions for treating agitation. The only authorized drug is risperidone (as well as brexpiprazole, approved by the FDA on 11 May 2023), which can be used for no longer than 6–12 weeks because it increases the risk of death—owing to cardiocerebrovascular accidents—by 1.6–1.7 times. Methods: In order to address the latter noteworthy unmet medical need, NanoBEO was produced. The aim of the present work is to generate the health technology assessment (HTA) of this nanotechnological device. The latter consists of a controlled release system, based on solid lipid nanoparticles loaded with bergamot essential oil (BEO). Results: The results of the present research assessed the current evidence in the field of non-pharmacological treatments for this condition, including relevant primary preclinical and clinical data studies supporting the use of this device and the production of the operative plan for its launch on the market. The findings offer recommendations for decision-making on its implementation in dementia. Conclusions: NanoBEO represents a public-worth innovation in this neglected area, marking a significant advancement in the history of dementia, moving from academic research to product development.

Solving partial differential equations for extremely large-scale systems within a feasible computation time serves in accelerating engineering developments. Quantum computing algorithms, particularly the Hamiltonian simulations, present a potential and promising approach to achieve this purpose. Actually, there are several oracle-based Hamiltonian simulations with potential quantum speedup, but their detailed implementations and accordingly the detailed computational complexities are all unclear. This paper presents a method that enables us to explicitly implement the quantum circuit for Hamiltonian simulation; the key technique is the explicit gate construction of differential operators contained in the target partial differential equation discretized by the finite difference method. Moreover, we show that the space and time complexities of the constructed circuit are exponentially smaller than those of conventional classical algorithms. We also provide numerical experiments and an experiment on a real device for the wave equation to demonstrate the validity of our proposed method.

The purposes of this study were to clarify the electromyography (EMG) of plantar flexors and to analyze the fascicle and tendon behaviors of the gastrocnemius medialis (GM) during running in the carbon-fiber plate embedded in thicker midsole racing shoes, such as the Nike ZoomX Vaporfly (VF) and traditional racing shoes (TRAD). We compared the fascicle and series elastic element behavior of the GM and EMG of the lower limb muscles during running (14 km/h, 45 s) in athletes wearing VF or TRAD. GM EMGs in the push-off phase were approximately 50% lower in athletes wearing VF than in TRAD. Although the series elastic element behavior and/or mean fascicle-shortening velocity during the entire stance phase were not significantly different between VF and TRAD, a significant difference was found in both the mean EMG and integral EMG of the GM during the push-off phase. EMG of the gastrocnemius lateralis (GL) during the first half of the push-off phase was significantly different between VF and TRAD. Present results suggest that VF facilitates running propulsion, resulting in a decrease in GM and GL EMGs at a given running velocity during the push-off phase, leading to a reduction in metabolic cost. [ABSTRACT FROM AUTHOR]

Se realizó la determinación de cafeína en ocho muestras de café procedentes de diferentes ciudades de la Amazonía Peruana, Colombia y Ecuador, con el objetivo de desarrollar una metodología para el análisis de rutina del contenido de cafeína en diversas muestras por cromatografía líquida de alta eficiencia de fase reversa. Este estudio se realizó usando una fase móvil de agua: metanol (75:25, v/v), a un flujo de 0,3 mL min-1 y una temperatura de 45 °C. La cafeína fue isocráticamente separada a 3,8 min. Las concentraciones de cafeína en las muestras se determinaron mediante una curva de calibración con estándar externo, las cuales se encontraron en el rango de 9,74 a 11,12 mg g-1 en café tostado molido, en 11,08 mg/g en cáscara de café y de 9,17 a 26,59 mg/g en café soluble liofilizado. Se obtuvieron recuperaciones de 68,34, 93,98 y 78,0 % para las fortificaciones de 50, 100 y 150 μg mL-1, respectivamente. Estos resultados indican que la metodología de cuantificación fue validada a través de un método de separación sencilla y rápida. El estudio permitió obtener concentraciones de cafeína en muestras de café de la región y sugerir el consumo promedio sin superar los límites saludables.

Child maltreatment can adversely affect brain development, leading to vulnerabilities in brain structure and function and various psychiatric disorders. Among the various types of child maltreatment, neglect has the highest incidence rate (76.0%); however, data on its sole adverse influence on the brain remain limited. This case-control brain magnetic resonance imaging (MRI) study identified the changes in gray matter structure and function that distinguish neglected children with no other type of maltreatment (Neglect group, n = 23) from typically developing children (TD group, n = 140), and investigated the association between these structural and functional differences and specific psychosocial phenotypes observed in neglected children. Our results showed that the Neglect group had a larger right and left anterior cingulate cortex (R/L.ACC) and smaller left angular gyrus (L.AG) gray matter volume. The larger R/L.ACC was associated with hyperactivity and inattention. Resting-state functional analysis showed increased functional connectivity (FC) between the left supramarginal gyrus (L.SMG) in the salience network (SN) and the right middle frontal gyrus (R.MFG) simultaneously with a decrease in FC with the L.ACC for the same seed. The increased FC for the R.MFG was associated with difficulty in peer problems and depressive symptoms; a mediating effect was evident for depressive symptoms. These results suggest that the structural atypicality of the R/L.ACC indirectly contributes to the disturbed FCs within the SN, thereby exacerbating depressive symptoms in neglected children. In conclusion, exposure to neglect in childhood may lead to maladaptive brain development, particularly neural changes associated with depressive symptoms.

Abstract Aim While moderate smartphone use contributes to information gathering and relationship building, excessive smartphone use, also referred to as problematic smartphone use (PSU), has raised concerns because of its addictive nature and associated health consequences. This study aimed to investigate the relationship between treatment readiness and prognosis in individuals with PSU and to assess the predictive ability of smartphone log data in evaluating treatment readiness. Methods A sample of 47 patients with PSU participated in this study. Treatment readiness was assessed using the Stages of Change, Readiness, and Treatment Eagerness Scale (SOCRATES), and log data were collected using a smartphone log application. Results The results showed a significant correlation between baseline SOCRATES scores and the difference in Global Assessment of Functioning scores between baseline and 6 months (Spearman's ρ = 0.640, P‐value = .001), suggesting that treatment readiness may explain part of the treatment outcomes (Pearson's r2 = 0.379, P‐value = 0.032). In addition, baseline log data, including the log acquisition rate, showed a positive correlation with treatment readiness (Spearman's ρ = 0.328, P‐value = 0.045). Conclusion These findings provide valuable insights into the relationship between treatment readiness and clinical outcomes in patients with PSU, and suggest the potential of log data as objective indicators of treatment motivation.

Cadmium (Cd) is a heavy metal that poses a threat to food safety via the ingestion of food products with Cd. The uptake of Cd by the cacao tree (Theobroma cacao) has gained attention after the European Union set limits for Cd in chocolate products, the main commodity produced from cacao beans. In this study, we analyzed levels of Cd in soils and plant tissues across five cacao farms in the Piura region of Peru to identify the origins of Cd accumulation, and the natural and human factors controlling its concentration. Our results show that Cd levels varied in the order: leaves (1.25 mg kg−1) > beans (0.78 mg kg−1) > soils at 5 cm (0.68 mg kg−1) > soils at 20 cm (0.6 mg kg−1). Our findings suggest that the higher concentration of Cd in plant tissues and surface soils can be explained by readily available Cd from fertilizers and a litter layer being absorbed, cycled, and accumulated by the plant. Moreover, even when fertilizers are within regulatory limits, their continuous application, combined with the biocycling of Cd, may lead to high Cd concentrations in beans and leaves. Conversely, farms on alluvial soils and more stable topographic positions display higher soil and plant Cd concentrations. Likewise, farms located at lower altitudes, with higher contributing areas are more likely to receive Cd transported through sediments and water in the river network. Our results also suggest that variations in the underlying geology and soil mineralogy may be a source of potentially Cd bearing sediments. Overall, this study indicates that the high levels of Cd in plants in the study area are the result of a combined mechanism involving plant bioaccumulation and high Cd in fertilizers for the most part, with a minor contribution from potential Cd bearing minerals in sediments of alluvial soils.

Abstract Background The short version of the smartphone addiction scale (SAS-SV) is widely used to measure problematic smartphone use (PSU). This study examined the validity and reliability of the SAS-SV among Japanese adults, as well as cross-sectional and longitudinal associations with relevant mental health traits and problems. Methods Datasets from a larger project on smartphone use and mental health were used to conduct two studies. Participants were adults aged over 20 years who carried a smartphone. Results Study 1 (n = 99,156) showed the acceptable internal consistency and structural validity of the SAS-SV with a bifactor model with three factors. For the test-retest reliability of the SAS-SV, the intraclass correlation coefficient (ICC) was .70, 95% CI [.69, 70], when the SAS-SV was measured seven and twelve months apart (n = 20,389). Study 2 (n = 3419) revealed that when measured concurrently, the SAS-SV was strongly positively correlated with another measure of PSU and moderately correlated with smartphone use time, problematic internet use (PIU), depression, the attentional factor of impulsiveness, and symptoms related to attention-deficit hyperactivity disorder and obsessive-compulsive disorder. When measured 12 months apart, the SAS-SV was positively strongly associated with another measure of PSU and PIU and moderately associated with depression. Discussion The structural validity of the SAS-SV appeared acceptable among Japanese adults with the bifactor model. The reliability of the SAS-SV was demonstrated in the subsequent seven- and twelve-month associations. Conclusion The cross-sectional and longitudinal associations of the SAS-SV provided further evidence regarding PSU characteristics.

Abstract Background Targeting of the apelin–apelin receptor (Apj) system may serve as a useful therapeutic intervention for the management of chronic kidney disease (CKD)‐induced skeletal muscle atrophy. We investigated the roles and efficacy of the apelin–Apj system in CKD‐induced skeletal muscle atrophy. Methods The 5/6‐nephrectomized mice were used as CKD models. AST‐120, a charcoal adsorbent of uraemic toxins (8 w/w% in diet), or apelin (1 μmol/kg) was administered to CKD mice to investigate the mechanism and therapeutic potential of apelin on CKD‐induced skeletal muscle atrophy. The effect of indoxyl sulfate, a uraemic toxin, or apelin on skeletal muscle atrophy was evaluated using mouse myoblast cells (C2C12 cells) in vitro. Results Skeletal muscle atrophy developed over time following nephrectomy at 12 weeks, as confirmed by a significant increase of atrogin‐1 and myostatin mRNA expression in the gastrocnemius (GA) muscle and a decrease of lower limb skeletal muscle weight (P

Abstract Yaku sika deer (Cervus nippon yakushimae) are endemic to Yakushima Island, whose landscape covered with primary evergreen forest is recognized as a World Heritage Site. In this study, the rumen bacterial microbiota (RBM) of wild Yaku sika was characterized using high throughput sequencing of bacterial 16S rRNA genes combined with targeted cultivation and functional analyses. Comparative analyses of RBM datasets from other ruminant animals revealed distinct community structure among domesticated and wild ruminants. Wild Yaku sika RBM exhibited higher species richness than other sika deer (i.e. wild Ezo sika and domesticated sika deer), likely reflecting their dietary variations associated with unique ecosystem in the island. The Yaku sika RBM of high deer population density samples exhibited higher diversity and contained higher proportion of Firmicutes than those of lower density samples. Moreover, the highest abundance of tannase gene were observed in individuals from the highest population density area, consistent with the previous observation that Yaku sika in the high density areas expanded their feed to include tannin-rich unpalatable plants. This study indicated that RBM of unique wild Yaku sika contribute to the flexibility of dietary shift and thus maintaining nutritional status of Yaku sika under high density conditions.

Abstract Dry etching of ternary metal carbides TiAlC has been first developed by transferring from wet etching to dry etching using a floating wire (FW)-assisted Ar/ammonium hydroxide vapor plasma. FW-assisted non-halogen vapor plasma generated at medium pressure can produce high-density reactive radicals (NH, H, and OH) for TiAlC surface modifications such as hydrogenation and methylamination. A proposed mechanism for dry etching of TiAlC is considered with the formation of the volatile products from the modified layer.