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209 results on '"Hamada, Satomi"'

2. Visualization of Learning Log of Web-Based Application for Understanding the Structure of Geometric Proofs

Author

Hamada, Satomi and Yamada, Masanori

Abstract

Many students are not good at geometric proofs. One reason for this is that it is possible to memorize the proof procedure explained by the teacher without understanding the structure of a geometric proof. So far, we have developed a web-based application that supports the understanding of the "structure of geometric proofs" in junior high school mathematics and have verified its effectiveness. Although the results of the evaluation experiments have indicated the usefulness of this web-based application, it was not possible to identify the factors that brought about its usefulness. In addition, because the web-based application was not equipped with a log analysis function, it was not possible to grasp the aspects that students struggle with during a proof in the web-based application. In this paper, we present the results and problems of the evaluation experiment of the web-based application so far and discuss the newly added log analysis function. [For the complete proceedings, see ED608557.]

Published
2019

9. Detachment Energy Evaluation in Nano-Particle Cleaning Using Lateral Force Microscopy.

Author

Terayama, Yutaka, Khajornrungruang, Panart, Seo, Jihoon, Hamada, Satomi, Wada, Yutaka, and Hiyama, Hirokuni

Subjects
LATERAL loads, SHEARING force, SHEAR flow, SURFACE cleaning, OXIDE coating
Abstract

It has been difficult to detach abrasive particles smaller than 50 nm from polished surfaces in post-CMP cleaning. During the cleaning process, the residual nano-particles exert shear force in the inevitable shear flow. In order to understand the cleaning mechanism, it is indispensable to investigate not only the force but also the energy acting on different-sized nano-particles. In this article, we proposed the evaluation of detachment energy (the energy required to detach nano-particles) by using Lateral Force Microscopy. As an example, the dominant detachment energy of the silica nano-particle between the oxide film is the potential energy of the hydrogen bond. It suggested that the silica nano-particle detachment involves the breaking of hydrogen bonds. [ABSTRACT FROM AUTHOR]

Published
2024
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21. Edoxaban eliminates hypercoagulability evoked by transient temperature changes in human whole blood.

Author

Suzuki, Anna, Hamada, Satomi, Oono, Ai, Hasegawa, Yuki, Yamauchi, Yasuteru, Okishige, Kaoru, Hirao, Kenzo, and Sasano, Tetsuo

Subjects
HEAT, TEMPERATURE, THROMBOPLASTIN, ANALYSIS of variance, ANTICOAGULANTS, SIMULATION methods in education, CATHETER ablation, COMPARATIVE studies, T-test (Statistics), BLOOD diseases, DESCRIPTIVE statistics, RESEARCH funding, DATA analysis software
Abstract

Background: Thrombosis is a common critical complication relating to radiofrequency catheter ablation and cryoablation. There is a possibility that high‐temperature stimulation during radiofrequency ablation or low‐temperature stimulation during cryoablation may affect the coagulability of blood. In this study, we aimed to determine the impacts of transient temperature stimulations on the coagulability of whole blood and to clarify if edoxaban suppressed the hypercoagulability. Methods: Citrated blood samples were drawn from 41 healthy subjects. Some blood samples were mixed with tissue factor (TF) and several concentrations of edoxaban (50, 100, and 200 ng/mL). Blood samples were exposed to several temperature stimulations for 1 min: heat stimulation (50°C) or cryostimulation (−20°C), and compared with control (37°C). Repeated cryostimulations or sequential cryo‐ and heat stimulation were also applied. Coagulability of whole blood was measured using a dielectric blood coagulometry. As an index of coagulability, the end of acceleration time (EAT) was used. Results: Both heat‐ and cryostimulations significantly shortened the EAT compared to the control, indicating that hypercoagulability was induced by temperature stimulations. Application of TF enhanced and extended the hypercoagulability after the temperature stimulations. Sequential application of cryo‐ followed by heat stimulation further enhanced the hypercoagulability of blood. Application of edoxaban increased the EAT in a concentration‐dependent manner in control condition. Edoxaban at 100 or 200 ng/mL completely suppressed the shortening of EAT evoked by these temperature stimulations. Conclusion: Transient temperature stimulations evoked hypercoagulability regardless of cryo‐ or heat stimulation. Edoxaban with 100 ng/mL or more eliminated this temperature‐stimulated hypercoagulability. [ABSTRACT FROM AUTHOR]

Published
2023
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