Search

Your search keyword '"Halpern, Allan C"' showing total 1,019 results
Start Over Author "Halpern, Allan C"
1,019 results on '"Halpern, Allan C"'

1. The SLICE-3D dataset: 400,000 skin lesion image crops extracted from 3D TBP for skin cancer detection

Author

Kurtansky, Nicholas R., D’Alessandro, Brian M., Gillis, Maura C., Betz-Stablein, Brigid, Cerminara, Sara E., Garcia, Rafael, Girundi, Marcela Alves, Goessinger, Elisabeth Victoria, Gottfrois, Philippe, Guitera, Pascale, Halpern, Allan C., Jakrot, Valerie, Kittler, Harald, Kose, Kivanc, Liopyris, Konstantinos, Malvehy, Josep, Mar, Victoria J., Martin, Linda K., Mathew, Thomas, Maul, Lara Valeska, Mothershaw, Adam, Mueller, Alina M., Mueller, Christoph, Navarini, Alexander A., Rajeswaran, Tarlia, Rajeswaran, Vin, Saha, Anup, Sashindranath, Maithili, Serra-García, Laura, Soyer, H. Peter, Theocharis, Georgios, Vos, Ayesha, Weber, Jochen, and Rotemberg, Veronica

Published
2024
Full Text
View/download PDF

2. BCN20000: Dermoscopic Lesions in the Wild

Author

Hernández-Pérez, Carlos, Combalia, Marc, Podlipnik, Sebastian, Codella, Noel C. F., Rotemberg, Veronica, Halpern, Allan C., Reiter, Ofer, Carrera, Cristina, Barreiro, Alicia, Helba, Brian, Puig, Susana, Vilaplana, Veronica, and Malvehy, Josep

Published
2024
Full Text
View/download PDF

3. Expert Agreement on the Presence and Spatial Localization of Melanocytic Features in Dermoscopy

Author

Liopyris, Konstantinos, Navarrete-Dechent, Cristian, Marchetti, Michael A., Rotemberg, Veronica, Apalla, Zoe, Argenziano, Giuseppe, Blum, Andreas, Braun, Ralph P., Carrera, Cristina, Codella, Noel C.F., Combalia, Marc, Dusza, Stephen W., Gutman, David A., Helba, Brian, Hofmann-Wellenhof, Rainer, Jaimes, Natalia, Kittler, Harald, Kose, Kivanc, Lallas, Aimilios, Longo, Caterina, Malvehy, Josep, Menzies, Scott, Nelson, Kelly C., Paoli, John, Puig, Susana, Rabinovitz, Harold S., Rishpon, Ayelet, Russo, Teresa, Scope, Alon, Soyer, H. Peter, Stein, Jennifer A., Stolz, Willhelm, Sgouros, Dimitrios, Stratigos, Alexander J., Swanson, David L., Thomas, Luc, Tschandl, Philipp, Zalaudek, Iris, Weber, Jochen, Halpern, Allan C., and Marghoob, Ashfaq A.

Published
2024
Full Text
View/download PDF

5. BCN20000: Dermoscopic Lesions in the Wild

Author

Combalia, Marc, Codella, Noel C. F., Rotemberg, Veronica, Helba, Brian, Vilaplana, Veronica, Reiter, Ofer, Carrera, Cristina, Barreiro, Alicia, Halpern, Allan C., Puig, Susana, and Malvehy, Josep

Subjects
Electrical Engineering and Systems Science - Image and Video Processing, Computer Science - Computer Vision and Pattern Recognition
Abstract

This article summarizes the BCN20000 dataset, composed of 19424 dermoscopic images of skin lesions captured from 2010 to 2016 in the facilities of the Hospital Cl\'inic in Barcelona. With this dataset, we aim to study the problem of unconstrained classification of dermoscopic images of skin cancer, including lesions found in hard-to-diagnose locations (nails and mucosa), large lesions which do not fit in the aperture of the dermoscopy device, and hypo-pigmented lesions. The BCN20000 will be provided to the participants of the ISIC Challenge 2019, where they will be asked to train algorithms to classify dermoscopic images of skin cancer automatically., Comment: Abstract for BCN20000

Published
2019

10. Clinical Presentations of Melanoma

Author

Halpern, Allan C., Marghoob, Ashfaq A., Sober, Arthur J., Mar, Victoria, Marchetti, Michael A., Balch, Charles M., editor, Atkins, Michael B., editor, Garbe, Claus, editor, Gershenwald, Jeffrey E., editor, Halpern, Allan C., editor, Kirkwood, John M., editor, McArthur, Grant A., editor, Thompson, John F., editor, and Sober, Arthur J., editor

Published
2020
Full Text
View/download PDF

11. International Skin Imaging Collaboration‐Designated Diagnoses (ISIC‐DX): Consensus terminology for lesion diagnostic labeling

Author

Scope, Alon, primary, Liopyris, Konstantinos, additional, Weber, Jochen, additional, Barnhill, Raymond L., additional, Braun, Ralph P., additional, Curiel‐Lewandrowski, Clara N., additional, Elder, David E., additional, Ferrara, Gerardo, additional, Grant‐Kels, Jane M., additional, Jeunon, Thiago, additional, Lallas, Aimilios, additional, Lin, Jennifer Y., additional, Marchetti, Michael A., additional, Marghoob, Ashfaq A., additional, Navarrete‐Dechent, Cristian, additional, Pellacani, Giovanni, additional, Soyer, Hans Peter, additional, Stratigos, Alexander, additional, Thomas, Luc, additional, Kittler, Harald, additional, Rotemberg, Veronica, additional, and Halpern, Allan C., additional

Published
2024
Full Text
View/download PDF

16. Improvement of diagnostic confidence and management of equivocal skin lesions by integration of reflectance confocal microscopy in daily practice: Prospective study in 2 referral skin cancer centers

Author

Yélamos, Oriol, Manubens, Elena, Jain, Manu, Chavez-Bourgeois, Marion, Pulijal, Sri V., Dusza, Stephen W., Marchetti, Michael A., Barreiro, Alicia, Marino, Maria L., Malvehy, Josep, Cordova, Miguel A., Rossi, Anthony M., Rajadhyaksha, Milind, Halpern, Allan C., Puig, Susana, Marghoob, Ashfaq A., and Carrera, Cristina

Published
2020
Full Text
View/download PDF

20. The state of melanoma: challenges and opportunities.

Author

Merlino, Glenn, Herlyn, Meenhard, Fisher, David E, Bastian, Boris C, Flaherty, Keith T, Davies, Michael A, Wargo, Jennifer A, Curiel-Lewandrowski, Clara, Weber, Michael J, Leachman, Sancy A, Soengas, Maria S, McMahon, Martin, Harbour, J William, Swetter, Susan M, Aplin, Andrew E, Atkins, Michael B, Bosenberg, Marcus W, Dummer, Reinhard, Gershenwald, Jeffrey E, Halpern, Allan C, Herlyn, Dorothee, Karakousis, Giorgos C, Kirkwood, John M, Krauthammer, Michael, Lo, Roger S, Long, Georgina V, McArthur, Grant, Ribas, Antoni, Schuchter, Lynn, Sosman, Jeffrey A, Smalley, Keiran S, Steeg, Patricia, Thomas, Nancy E, Tsao, Hensin, Tueting, Thomas, Weeraratna, Ashani, Xu, George, Lomax, Randy, Martin, Alison, Silverstein, Steve, Turnham, Tim, and Ronai, Ze'ev A

Subjects
Humans, Melanoma, Signal Transduction, Biomedical Research, Societies, Scientific, dormancy, early diagnosis, melanoma, metastasis, prevention, therapy, Cancer, Prevention, Vaccine Related, early diagnosis, Biological Sciences, Medical and Health Sciences, Dermatology & Venereal Diseases
Abstract

The Melanoma Research Foundation (MRF) has charted a comprehensive assessment of the current state of melanoma research and care. Intensive discussions among members of the MRF Scientific Advisory Council and Breakthrough Consortium, a group that included clinicians and scientists, focused on four thematic areas - diagnosis/early detection, prevention, tumor cell dormancy (including metastasis), and therapy (response and resistance). These discussions extended over the course of 2015 and culminated at the Society of Melanoma Research 2015 International Congress in November. Each of the four groups has outlined their thoughts as per the current status, challenges, and opportunities in the four respective areas. The current state and immediate and long-term needs of the melanoma field, from basic research to clinical management, are presented in the following report.

Published
2016

21. BCN20000: dermoscopic lesions in the wild

Author

Universitat Politècnica de Catalunya. Departament de Teoria del Senyal i Comunicacions, Universitat Politècnica de Catalunya. IDEAI-UPC - Intelligent Data sciEnce and Artificial Intelligence Research Group, Hernández Pérez, Carlos, Combalia Escudero, Marc, Podlipnik, Sebastian, Codella, Noel C. F., Rotemberg, Veronica, Halpern, Allan C., Reiter, Ofer, Carrera Álvarez, Cristina, Barreiro Capurro, Alicia, Helba, Brian, Puig Sardá, Susana, Vilaplana Besler, Verónica, Malvehy Guilera, Josep, Universitat Politècnica de Catalunya. Departament de Teoria del Senyal i Comunicacions, Universitat Politècnica de Catalunya. IDEAI-UPC - Intelligent Data sciEnce and Artificial Intelligence Research Group, Hernández Pérez, Carlos, Combalia Escudero, Marc, Podlipnik, Sebastian, Codella, Noel C. F., Rotemberg, Veronica, Halpern, Allan C., Reiter, Ofer, Carrera Álvarez, Cristina, Barreiro Capurro, Alicia, Helba, Brian, Puig Sardá, Susana, Vilaplana Besler, Verónica, and Malvehy Guilera, Josep

Abstract

Advancements in dermatological artificial intelligence research require high-quality and comprehensive datasets that mirror real-world clinical scenarios. We introduce a collection of 18,946 dermoscopic images spanning from 2010 to 2016, collated at the Hospital Clínic in Barcelona, Spain. The BCN20000 dataset aims to address the problem of unconstrained classification of dermoscopic images of skin cancer, including lesions in hard-to-diagnose locations such as those found in nails and mucosa, large lesions which do not fit in the aperture of the dermoscopy device, and hypo-pigmented lesions. Our dataset covers eight key diagnostic categories in dermoscopy, providing a diverse range of lesions for artificial intelligence model training. Furthermore, a ninth out-of-distribution (OOD) class is also present on the test set, comprised of lesions which could not be distinctively classified as any of the others. By providing a comprehensive collection of varied images, BCN20000 helps bridge the gap between the training data for machine learning models and the day-to-day practice of medical practitioners. Additionally, we present a set of baseline classifiers based on state-of-the-art neural networks, which can be extended by other researchers for further experimentation., We acknowledge the support of the International Skin Imaging Collaboration (ISIC). This research was supported by the Spanish Research Agency (AEI) under project PID2020-116907RB-I00 of the call MCIN/ AEI /10.13039/501100011033 and the project 718/C/2019 with id 201923-30 and 201923-31, funded by Fundació la Marató de TV3, iTOBOs grant from the European Union’s Horizon 2020 research and innovation programme num 965221. Other funding sources include the Melanoma Research Alliance Young Investigator Award 614197. This research was funded in part through the NIH/NCI Cancer Center Support Grant P30 CA008748., Peer Reviewed, Postprint (published version)

Published
2024

22. NF1 Mutations Are Common in Desmoplastic Melanoma

Author

Wiesner, Thomas, Kiuru, Maija, Scott, Sasinya N, Arcila, Maria, Halpern, Allan C, Hollmann, Travis, Berger, Michael F, and Busam, Klaus J

Subjects
Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Cancer, Neurofibromatosis, Rare Diseases, Neurosciences, Adult, Aged, Aged, 80 and over, Biomarkers, Tumor, DNA Mutational Analysis, Female, Genes, Neurofibromatosis 1, Genetic Predisposition to Disease, High-Throughput Nucleotide Sequencing, Humans, Male, Melanoma, Middle Aged, Mutation, Phenotype, Skin Neoplasms, Young Adult, desmoplastic melanoma, neurofibromin 1, mutation, next-generation sequencing, Clinical Sciences, Pathology, Clinical sciences
Abstract

Desmoplastic melanoma (DM) is a rare variant of melanoma with distinct clinical, histopathologic, and immunohistochemical features. Clinically, DM differs from conventional melanoma by a higher propensity for local recurrence and less frequent metastatic spread to regional lymph nodes. In its pure form, DM has a distinct appearance displaying a low density of fusiform melanocytes in a collagen-rich matrix. Whereas a number of mutations have been identified in primary melanoma, including BRAF, NRAS, GNAQ, GNA11, and KIT, and the occurrence of these mutations has been found to correlate to some extent with the histopathologic features, anatomic site, and/or mode of sun exposure, no distinct set of mutations has so far been reported for DM. To study the potential association of neurofibromin (NF1) mutations with DM, we examined 15 desmoplastic and 20 non-DMs by next-generation sequencing. Mutations of the NF1 gene were found in 14 of 15 (93%) DMs and 4 of 20 (20%) non-DMs. The high frequency of NF1 mutations in DMs suggests an important role for NF1 in the biology of this type of melanoma.

Published
2015

25. Desmoplastic Melanoma With Sarcomatoid Dedifferentiation

Author

Kiuru, Maija, McDermott, Gregory, Berger, Michael, Halpern, Allan C, and Busam, Klaus J

Subjects
Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Cancer, Rare Diseases, Aged, Biomarkers, Tumor, Biopsy, Cell Dedifferentiation, Head and Neck Neoplasms, Humans, Immunohistochemistry, Male, Melanoma, Neoplasms, Complex and Mixed, Phenotype, Sarcoma, Scalp, Skin Neoplasms, desmoplastic melanoma, sarcoma, biphenotypic tumor, next-generation sequencing, Clinical Sciences, Pathology, Clinical sciences
Abstract

Desmoplastic melanoma (DM) is a variant of melanoma, which typically affects chronically sun-damaged skin of elderly patients. Pure DM displays a low density of fusiform melanocytes in a collagen-rich matrix. In mixed DM, tumor cell density is higher, and parts of the tumor lack abundant stromal fibrosis. Both pure and mixed DMs usually express S100 protein homogenously. We report herein an unusual biphenotypic tumor characterized by the association of a pure DM with an undifferentiated solid spindle cell nodule. It occurred on the scalp of a 66-year-old man. A biopsy of the undifferentiated spindle cell nodule was initially interpreted at a commercial laboratory as atypical fibroxanthoma. The pure DM was seen only in the excisional specimen. All cells of the pure DM stained for S100 protein and SOX10. The adjacent solid sarcomatoid spindle cell nodule lacked expression of S100 protein, SOX10, as well as melan-A, gp100, and microphthalmia-associated transcription factor in >95% of its tumor cells. Although focal expression of melanocyte differentiation antigens in the solid tumor component made us favor a combined DM with sarcomatoid dedifferentiation, we also considered the possibility of a collision scenario, that is, a pleomorphic dermal sarcoma incidentally colliding with a DM. To further assess a possible relationship of the sarcomatoid nodule with the DM, we performed next-generation sequencing analysis on each component separately. The analysis revealed shared chromosomal copy number changes and a high number of common mutations, thereby supporting the concept of a DM with a dedifferentiated sarcomatoid component. An interesting finding is the presence of mutations of the neurofibromin 1 (NF1) gene in both tumor components.

Published
2014

26. Guidelines of care for the management of primary cutaneous melanoma

Author

Swetter, Susan M., Tsao, Hensin, Bichakjian, Christopher K., Curiel-Lewandrowski, Clara, Elder, David E., Gershenwald, Jeffrey E., Guild, Valerie, Grant-Kels, Jane M., Halpern, Allan C., Johnson, Timothy M., Sober, Arthur J., Thompson, John A., Wisco, Oliver J., Wyatt, Samantha, Hu, Shasa, and Lamina, Toyin

Published
2019
Full Text
View/download PDF

29. Results of the 2016 International Skin Imaging Collaboration International Symposium on Biomedical Imaging challenge: Comparison of the accuracy of computer algorithms to dermatologists for the diagnosis of melanoma from dermoscopic images

Author

Marchetti, Michael A., Codella, Noel C.F., Dusza, Stephen W., Gutman, David A., Helba, Brian, Kalloo, Aadi, Mishra, Nabin, Carrera, Cristina, Celebi, M. Emre, DeFazio, Jennifer L., Jaimes, Natalia, Marghoob, Ashfaq A., Quigley, Elizabeth, Scope, Alon, Yélamos, Oriol, and Halpern, Allan C.

Published
2018
Full Text
View/download PDF

37. Supplementary Table 1 from Primary T Cells from Cutaneous T-cell Lymphoma Skin Explants Display an Exhausted Immune Checkpoint Profile

Author

Querfeld, Christiane, primary, Leung, Samantha, primary, Myskowski, Patricia L., primary, Curran, Shane A., primary, Goldman, Debra A., primary, Heller, Glenn, primary, Wu, Xiwei, primary, Kil, Sung Hee, primary, Sharma, Sneh, primary, Finn, Kathleen J., primary, Horwitz, Steven, primary, Moskowitz, Alison, primary, Mehrara, Babak, primary, Rosen, Steven T., primary, Halpern, Allan C., primary, and Young, James W., primary

Published
2023
Full Text
View/download PDF

38. Supplemental Figure 1 from Primary T Cells from Cutaneous T-cell Lymphoma Skin Explants Display an Exhausted Immune Checkpoint Profile

Author

Querfeld, Christiane, primary, Leung, Samantha, primary, Myskowski, Patricia L., primary, Curran, Shane A., primary, Goldman, Debra A., primary, Heller, Glenn, primary, Wu, Xiwei, primary, Kil, Sung Hee, primary, Sharma, Sneh, primary, Finn, Kathleen J., primary, Horwitz, Steven, primary, Moskowitz, Alison, primary, Mehrara, Babak, primary, Rosen, Steven T., primary, Halpern, Allan C., primary, and Young, James W., primary

Published
2023
Full Text
View/download PDF

39. Supplemental Figure 1 legend. from Primary T Cells from Cutaneous T-cell Lymphoma Skin Explants Display an Exhausted Immune Checkpoint Profile

Author

Querfeld, Christiane, primary, Leung, Samantha, primary, Myskowski, Patricia L., primary, Curran, Shane A., primary, Goldman, Debra A., primary, Heller, Glenn, primary, Wu, Xiwei, primary, Kil, Sung Hee, primary, Sharma, Sneh, primary, Finn, Kathleen J., primary, Horwitz, Steven, primary, Moskowitz, Alison, primary, Mehrara, Babak, primary, Rosen, Steven T., primary, Halpern, Allan C., primary, and Young, James W., primary

Published
2023
Full Text
View/download PDF

40. Supplemental Figure 2 from Primary T Cells from Cutaneous T-cell Lymphoma Skin Explants Display an Exhausted Immune Checkpoint Profile

Author

Querfeld, Christiane, primary, Leung, Samantha, primary, Myskowski, Patricia L., primary, Curran, Shane A., primary, Goldman, Debra A., primary, Heller, Glenn, primary, Wu, Xiwei, primary, Kil, Sung Hee, primary, Sharma, Sneh, primary, Finn, Kathleen J., primary, Horwitz, Steven, primary, Moskowitz, Alison, primary, Mehrara, Babak, primary, Rosen, Steven T., primary, Halpern, Allan C., primary, and Young, James W., primary

Published
2023
Full Text
View/download PDF

41. Supplemental Figure 2 legend. from Primary T Cells from Cutaneous T-cell Lymphoma Skin Explants Display an Exhausted Immune Checkpoint Profile

Author

Querfeld, Christiane, primary, Leung, Samantha, primary, Myskowski, Patricia L., primary, Curran, Shane A., primary, Goldman, Debra A., primary, Heller, Glenn, primary, Wu, Xiwei, primary, Kil, Sung Hee, primary, Sharma, Sneh, primary, Finn, Kathleen J., primary, Horwitz, Steven, primary, Moskowitz, Alison, primary, Mehrara, Babak, primary, Rosen, Steven T., primary, Halpern, Allan C., primary, and Young, James W., primary

Published
2023
Full Text
View/download PDF

42. Data from Primary T Cells from Cutaneous T-cell Lymphoma Skin Explants Display an Exhausted Immune Checkpoint Profile

Author

Querfeld, Christiane, primary, Leung, Samantha, primary, Myskowski, Patricia L., primary, Curran, Shane A., primary, Goldman, Debra A., primary, Heller, Glenn, primary, Wu, Xiwei, primary, Kil, Sung Hee, primary, Sharma, Sneh, primary, Finn, Kathleen J., primary, Horwitz, Steven, primary, Moskowitz, Alison, primary, Mehrara, Babak, primary, Rosen, Steven T., primary, Halpern, Allan C., primary, and Young, James W., primary

Published
2023
Full Text
View/download PDF

45. Agreement Between Experts and an Untrained Crowd for Identifying Dermoscopic Features Using a Gamified App: Reader Feasibility Study

Author

Kentley, Jonathan, primary, Weber, Jochen, additional, Liopyris, Konstantinos, additional, Braun, Ralph P, additional, Marghoob, Ashfaq A, additional, Quigley, Elizabeth A, additional, Nelson, Kelly, additional, Prentice, Kira, additional, Duhaime, Erik, additional, Halpern, Allan C, additional, and Rotemberg, Veronica, additional

Published
2023
Full Text
View/download PDF

47. Response to Harms et al.

Author

Marchetti, Michael A., primary, Kurtansky, Nicholas R., additional, Dusza, Stephen W., additional, Marghoob, Ashfaq A., additional, Rotemberg, Veronica M., additional, and Halpern, Allan C., additional

Published
2022
Full Text
View/download PDF

49. Indications for Digital Monitoring of Patients With Multiple Nevi: Recommendations from the International Dermoscopy Society

Author

Russo, Teresa, primary, Piccolo, Vincenzo, additional, Moscarella, Elvira, additional, Tschandl, Philipp, additional, Kittler, Harald, additional, Paoli, John, additional, Lallas, Aimilios, additional, Braun, Ralph P, additional, Thomas, Luc, additional, Soyer, H Peter, additional, Malvehy, Josep, additional, Puig, Susana, additional, Marghoob, Ashfaq, additional, Scope, Alon, additional, Blum, Andreas, additional, Halpern, Allan C, additional, Cabo, Horacio, additional, Menzies, Scott, additional, Stolz, Wilhem, additional, Tanaka, Masaru, additional, Rabinovitz, Harold, additional, Hofmann-Wellenhof, Rainer, additional, Bakos, Renato Marchiori, additional, Zalaudek, Iris, additional, Pellacani, Giovanni, additional, Veiga, Anna Varela, additional, Maceiras, Laura Rosende, additional, De las Heras-Sotos, Cristina, additional, and Argenziano, Giuseppe, additional

Published
2022
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results