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Your search keyword '"Halmesmäki, Esa"' showing total 9 results
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9 results on '"Halmesmäki, Esa"'

3. TOWARD A CONTINGENCY MODEL FOR HOSPITAL-BASED HEALTH TECHNOLOGY ASSESSMENT: EVIDENCE FROM ADHOPHTA PROJECT

Author

Cicchetti, Americo, primary, Iacopino, Valentina, additional, Coretti, Silvia, additional, Fiore, Alessandra, additional, Marchetti, Marco, additional, Sampietro-Colom, Laura, additional, Kidholm, Kristian, additional, Wasserfallen, Jean-Blaise, additional, Kahveci, Rabia, additional, Halmesmäki, Esa, additional, Rosenmöller, Magdalene, additional, Wild, Claudia, additional, and Kivet, Raul-Allan, additional

Published
2018
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4. The AdHopHTA handbook: a handbook of hospital-based Health Technology Assessment (HB-HTA)

Author

Sampietro Colom, Laura, Lach, Krzysztof, Haro, Irene Escolar, Sroka, Sylwia, Cicchetti, Americo, Marchetti, Marco, Iacopino, Valentina, Kidholm, Kristian, Ølholm, Anne Mette, Birk Olsen, Mette, Pasternack, Iris, Roine, Risto P., Halmesmäki, Esa, Fure, Brynjar, Arentz Hansen, Helene, Frønsdal, Katrine Bjørnebek, Rosenmöller, Magdalene, Ribeiro, Marta, Garcia, Esther Vizcaino, Wild, Claudia, Patera, Nikolaus, Fischer, Stefan, Kisser, Agnes, Kahveci, Rabia, Tutuncu, Tanju, Yuksek, Yunus Nadi, Kucuk, Emine Ozer, Wasserfallen, Jean Blaise, Pinget, Christophe, Kiivet, Raul – Allan, and Ulst, Margus

Subjects
Settore SECS-P/10 - ORGANIZZAZIONE AZIENDALE, Hospital-Based Health Technology Assessment, Health Care Organizations, Settore MED/42 - IGIENE GENERALE E APPLICATA
Published
2015

5. Hospital-based health technology assessment (HTA) in Finland

Author

University of Helsinki, Clinicum, University of Helsinki, Faculty of Medicine (-2009), Halmesmäki, Esa, Pasternack, Iris, Roine, Risto Paavo Antero, University of Helsinki, Clinicum, University of Helsinki, Faculty of Medicine (-2009), Halmesmäki, Esa, Pasternack, Iris, and Roine, Risto Paavo Antero

Abstract

Background: This study examines, as a part of the European Union funded Adopting Hospital Based Health Technology Assessment (AdHopHTA) project, the results and barriers of collaboration between Finnish hospitals and the national health technology assessment (HTA) agency, Finohta. A joint collaborative HTA program has existed since 2006 between the Finnish hospitals and the national agency. Methods: A case study method was used. Information about the collaboration between Finnish hospitals and Finohta was retrieved from interviews and publications, and categorised per theme. Hypotheses and indicators of successful collaboration were determined beforehand and reflected on the observations from the interviews and literature. Results: Overall, 48 collaborative HTA reports have been performed during 7 years of collaboration. However, there were no clear indications that the use of HTA information or the transparency of decision-making regarding new technologies would have increased in hospitals. The managerial commitment to incorporate HTAs into the decision-making processes in hospitals was still low. The quality of the collaborative HTA reports was considered good, but their applicability in the hospital setting limited. There were differing expectations about the timing and relevance of the content. Signs of role conflict and mistrust were observed. Conclusions: Despite collaborative efforts to produce HTAs for hospitals, the impact of HTA information on hospital decision-making appears to remain low. The difficulties identified in this case study, such as lack of managerial commitment in hospitals, can hopefully be better addressed in the future with the guidance and tools having been developed in the AdHopHTA project. Collaboration between hospitals and national HTA agencies remains important for the efficient sharing of skills and resources.

Published
2016

7. Hospital managers’ need for information in decision-making – An interview study in nine European countries

Author

Kidholm, Kristian, primary, Ølholm, Anne Mette, additional, Birk-Olsen, Mette, additional, Cicchetti, Americo, additional, Fure, Brynjar, additional, Halmesmäki, Esa, additional, Kahveci, Rabia, additional, Kiivet, Raul-Allan, additional, Wasserfallen, Jean-Blaise, additional, Wild, Claudia, additional, and Sampietro-Colom, Laura, additional

Published
2015
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9. Changes in subchondral bone mineral density and collagen matrix organization in growing horses ☆ [☆] Sources of funding: Financial support was received from the Ministry of Education in Finland (projects 25/627/2006 and 61/627/2005), Academy of Finland (projects 113112, 213548, and 216231), the National Graduate School of Musculo-Skeletal Diseases in Finland and the North-Savo Fund of the Finnish Cultural Foundation. The GEXA study is a project by the Global Equine Research Alliance for which the financial support was granted by the Marilyn Simpson Trust (USA), Horserace Betting Levy Board (UK), Utrecht University (The Netherlands) and the New Zealand Racing Board.

Author

Holopainen, Jaakko T., Brama, Pieter A.J., Halmesmäki, Esa, Harjula, Terhi, Tuukkanen, Juha, van Weeren, P. René, Helminen, Heikki J., and Hyttinen, Mika M.

Subjects
*BONE density, *COLLAGEN, *TOMOGRAPHY, *EXTRACELLULAR matrix proteins, *POLARIZATION microscopy, HORSE growth
Abstract

Abstract: Objective: The effects of growth and maturation on the mineral deposition and the collagen framework of equine subchondral bone (SCB) were studied. Materials and methods: Osteochondral specimens (diameter 6 mm) from the left metacarpophalangeal joint of 5-(n =8), 11-(n =8) and 18-month-old (n =6) horses were investigated at two differently loaded sites (Site 1 (S1): intermittent peak loading; Site 2 (S2): habitual loading). The SCB mineral density (BMD) was measured with peripheral quantitative computer tomography (pQCT), and the data were adjusted against the volume fraction (Vv) of the bone extracellular matrix (ECM). Polarised light microscopy (PLM) was used to analyze the Vv, the collagen fibril parallelism index and the orientation angle distribution in two fractions (1 mm/fraction) beneath the osteochondral junction of the SCB. PLM analysis was made along two randomly selected perpendicularly oriented vertical sections to measure the tissue anisotropy in the x-, y-, and z-directions. Results: The BMD of SCB at S1 and S2 increased significantly during maturation. At the same time, the Vv of the ECM increased even more. This meant that the Vv-adjusted BMD decreased. There were no significant differences between sites. The basic collagen fibril framework of SCB seems to be established already at the age of 5 months. During maturation, the extracellular matrix underwent a decrease in collagen fibril parallelism but no changes in collagen orientation. The variation was negligible in the collagen network estimates in the two section planes. Conclusions: Growth and maturation induce significant changes in the equine SCB. The BMD increase in SCB is primarily due to the growth of bone volume and not to any increase in mineral deposition. An increase in weight-bearing appears to greatly affect the BMD and the volume of the extracellular matrix. Growth and maturation induce a striking change in collagen fibril parallelism but not in fibril orientation. The structural anisotropy of the subchondral bone is significant along the vertical (x–y) direction but not in the transversal (z) direction. [Copyright &y& Elsevier]

Published
2008
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