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1. Diagnosis and treatment of exocrine pancreatic insufficiency in chronic pancreatitis: An international expert survey and case vignette study

Author

Falconi, Massimo, Zou, Wen-Bin, Engjom, Trond, Ooi, Chee Y., Sutton, Robert, Frulloni, Luca, Neoptolemos, John, Wilcox, Charles, Miroslav, Vujasinovic, Trikudanathan, Guru, Liao, Zhuan, Hauge, Truls, Mössner, Joachim, Hoge, Chantal, Fockens, Paul, Mieog, Sven, Capurso, Gabriele, Cui, Yunfeng, de Madaria, Enrique, Distler, Marius, Aghdassi, Ali, Whitcomb, David C., Russell, Kylie, Beyer, Georg, Kunovsky, Lumír, Kwanten, Wilhelmus, Nava, Andrea Kazemi, Conlon, Kevin, Siriwardena, A.K., Paiella, Salvatore, Alconchel, Felipe, Marino, Marco Vito, de Meijer, Vincent E., Domingo, Carlos, Kleeff, Jorg, Lakshmanan, Aarti, Lie Chu, Michael Jen, Bouwense, Stefan, Nashidengo, Pueya Rashid, Konstantinos, Perivoliotis, Muttillo, Edoardo Maria, Umar, Garzali Ibrahim, Castro Santiago, Maria Jesus, Lopez-Lopez, Victor, Torri, Francesco, Schmelzle, Moritz, Ignatavicius, Povilas, Wicherts, Dennis, Gomes, Antonio, Machairas, Nikolaos A., Dorovinis, Panagiotis I., Serrablo, Alejandro, Soreide, Kjetil, Rahbari, Mohammad, Jie Chu, Michael Jen, Ptasnuka, Margarita, Petrulionis, Marius, Noel, Colin Byron, Castro, Ernest, Di Martino, Marcello, Recordare, Alfonso, Stättner, Stefan, Ausania, Fabio, Hartman, Vera, Roeyen, Geert, Egorov, Viacheslav, Vanagas, Tomas, Ebrahim, Mohamed, Arabadzhieva, Elena, Malleo, Giuseppe, Li, Liang, Adams, David, Oracz, Grzegorz, Nageshwar, Reddy D., Waldthaler, Alexander, Masamune, Atsushi, Drewes, Asbjorn Mohr, Amodio, Antonio, Tirkes, Temel, Srivastava, Anshu, Beilman, Gregory J., Berger, Zoltan, Lindkvist, Bjorn, Cavestro, Giulia Martina, Gariepy, Cheryl, Czakó, Laszlo, Di Leo, Milena, Sharma, Vishal, Lakhtakia, Sundeep, Rana, Surinder Singh, Duggan, Sinaed N., Kwon, Chang-Il, Phillips, Anna Evans, Forsmark, Christopher E., Gleeson, Ferga C., Lehman, Glen A., Greenhalf, William, Costamagna, Guido, Halloran, Christopher M., Friess, Helmut, Rasmussen, Henrik Hojgaard, Ikeura, Tsukasa, Haldorsen, Ingfrid S., Itoi, Takao, Izbicki, Jacob R., Windsor, John, Poulsen, Jakob Lykke, Frokjaer, Jens Brondum, Larino-Noia, Jose, Wang, Dan, Garcia, Julio Iglesias, Kalaitzakis, Evangelos, Wertheim-Tysarowska, Kararzyna, Kubota, Kensuke, Larusch, Jessica, Lerch, Markus M., Hu, Liang-Hao, Erkan, Mert, Machicado, Jorg D., Arvanitakis, Marianna, Buchler, Markus W., Levy, Marlon F., Heyman, Melvin B., Nojgaard, Camilla, Khashab, Mouen A., Delhaye, Myriam, Ogura, Takeshi, Okazaki, Kazuichi, Ghaneh, Paula, Banks, Peter A., Gupta, Pankaj, Papachristou, Georgios I., Michl, Patrick, Levy, Philippe, Pukitis, Aldis, Pezzilli, Raffaele, Baron, Ryan D., Amann, Stephen T., Schwarzenberg, Sarah Jane, Isaji, Shuiji, Olesen, Soren Schou, Novovic, Srdan, Hughes, Steven J., Werlin, Steven L., Gonska, Tanja, Gardner, Timothy B., Topazian, Mark D., Weiss, Frank Ulrich, Akshintala, Venakata S., Morinville, Veronique D., Rebours, Vinciane, Vincze, Aron, Singh, Vikesh K., Cui, Naiqiang, Zhang, Hong, Li, Zhao-shen, de Rijk, Florence E.M., van Veldhuisen, Charlotte L., Besselink, Marc G., van Hooft, Jeanin E., van Santvoort, Hjalmar C., van Geenen, Erwin J.M., Hegyi, Peter, Löhr, J-Matthias, Dominguez-Munoz, Juan E., de Jonge, Pieter Jan F., Bruno, Marco J., and Verdonk, Robert C.

Published
2022
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3. International consensus guidelines on surveillance for pancreatic cancer in chronic pancreatitis. Recommendations from the working group for the international consensus guidelines for chronic pancreatitis in collaboration with the International Association of Pancreatology, the American Pancreatic Association, the Japan Pancreas Society, and European Pancreatic Club

Author

Greenhalf, William, Lévy, Philippe, Gress, Thomas, Rebours, Vinciane, Brand, Randall E., Pandol, Steve, Chari, Suresh, Jørgensen, Maiken Thyregod, Mayerle, Julia, Lerch, Markus M., Hegyi, Péter, Kleeff, Jörg, Castillo, Carlos Fernández-del, Isaji, Shuiji, Shimosegawa, Tooru, Sheel, Andrea, Halloran, Christopher M, Garg, Pramod, Takaori, Kyoichi, Besselink, Marc G., Forsmark, Chris E., Wilcox, C.Mel, Maisonneuve, Patrick, Yadav, Dhiraj, Whitcomb, David, and Neoptolemos, John

Published
2020
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4. Management of the pancreatic transection plane after left (distal) pancreatectomy: Expert consensus guidelines by the International Study Group of Pancreatic Surgery (ISGPS)

Author

Miao, Yi, Büchler, Markus W., Fernandez-del Castillo, Carlos, Neoptolemos, John P., Dervenis, Christos, Ghaneh, Paula, Kleeff, Jörg, Shrikhande, Shailesh V., Falconi, Massimo, Takaori, Kyoichi, Tanaka, Masao, Shimosegawa, Tooru, Peng, Yunpeng, Wang, Guangfu, Huang, Xumin, Lu, Zipeng, Yeo, Charles J., Vollmer, Charles M., Jr., Halloran, Christopher M., de Rooij, Thijs, Werner, Jens, Friess, Helmut, Zeh, Herbert J., Izbicki, Jakob R., He, Jin, Laukkarinen, Johanna, Dejong, Cees H., Lillemoe, Keith D., Conlon, Kevin, Gianotti, Luca, Besselink, Marc G., Del Chiaro, Marco, Montorsi, Marco, Bockhorn, Maximilian, Adham, Mustapha, Oláh, Attila, Salvia, Roberto, Hackert, Thilo, Zureikat, Amer H., Ceyhan, Güralp O., and Bassi, Claudio

Published
2020
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5. Postpancreatectomy Acute Pancreatitis (PPAP): Definition and Grading from the International Study Group for Pancreatic Surgery (ISGPS)

Author

Marchegiani, Giovanni, Barreto, Savio George, Bannone, Elisa, Sarr, Michael, Vollmer, Charles M., Connor, Saxon, Falconi, Massimo, Besselink, Marc G., Salvia, Roberto, Wolfgang, Christopher L., Zyromski, Nicholas J., Yeo, Charles J., Adham, Mustapha, Siriwardena, Ajith K., Takaori, Kyoichi, Hilal, Mohammad Abu, Loos, Martin, Probst, Pascal, Hackert, Thilo, Strobel, Oliver, Busch, Olivier R. C., Lillemoe, Keith D., Miao, Yi, Halloran, Christopher M., Werner, Jens, Friess, Helmut, Izbicki, Jakob R., Bockhorn, Maximillian, Vashist, Yogesh K., Conlon, Kevin, Passas, Ioannis, Gianotti, Luca, Del Chiaro, Marco, Schulick, Richard D., Montorsi, Marco, Oláh, Attila, Fusai, Giuseppe Kito, Serrablo, Alejandro, Zerbi, Alessandro, Fingerhut, Abe, Andersson, Roland, Padbury, Robert, Dervenis, Christos, Neoptolemos, John P., Bassi, Claudio, Büchler, Markus W., and Shrikhande, Shailesh V.

Published
2021
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10. Partial pancreatoduodenectomy versus duodenum-preserving pancreatic head resection in chronic pancreatitis: the multicentre, randomised, controlled, double-blind ChroPac trial

Author

Rossion, Inga, Kunz, Alexandra, Hund, Evelin, Limprecht, Ronald, Schlitt, Hans Jürgen, Mössner, Joachim, Seiler, Christoph M, Ihorst, Gabriele, Di Sebastiano, Pierluigi, Witzigmann, Helmut, Klein, Fritz, Berthold, Heike, Körnlein, Heike, Hopt, Ulrich, Sick, Olivia, Keck, Tobias, Partecke, Lars Ivo, Peters, Sebastian, Lerch, Markus M, Maichle, Barbara, Erni, Birgit, Bunjes-Schmieger, Sabine, Igel, Sarah, Stemmle, Svenja, Neoptolemos, John P, Raraty, Michael G T, Petric, Miha, Niedergethmann, Marco, Schwarzmeier, Claudia, Renz, Bernhard, Schreib, Brigitte, Thasler, Wolfgang E, Schoenberg, Michael H, Friess, Helmut, Reim, Daniel, Ceyhan, Güralp O, Diehl-Bein, Monika, Simon, Thomas, Gehrig, Tobias, Hoffer, Marion, Germer, Christoph Thomas, Diener, Markus K, Hüttner, Felix J, Kieser, Meinhard, Knebel, Phillip, Dörr-Harim, Colette, Distler, Marius, Grützmann, Robert, Wittel, Uwe A, Schirren, Rebekka, Hau, Hans-Michael, Kleespies, Axel, Heidecke, Claus-Dieter, Tomazic, Ales, Halloran, Christopher M, Wilhelm, Torsten J, Bahra, Marcus, Beckurts, Tobias, Börner, Thomas, Glanemann, Matthias, Steger, Ulrich, Treitschke, Frank, Staib, Ludger, Thelen, Karsten, Bruckner, Thomas, Mihaljevic, André L, Werner, Jens, Ulrich, Alexis, Hackert, Thilo, and Büchler, Markus W

Published
2017
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11. Comparison of adjuvant gemcitabine and capecitabine with gemcitabine monotherapy in patients with resected pancreatic cancer (ESPAC-4): a multicentre, open-label, randomised, phase 3 trial

Author

Neoptolemos, John P, Palmer, Daniel H, Ghaneh, Paula, Psarelli, Eftychia E, Valle, Juan W, Halloran, Christopher M, Faluyi, Olusola, O'Reilly, Derek A, Cunningham, David, Wadsley, Jonathan, Darby, Suzanne, Meyer, Tim, Gillmore, Roopinder, Anthoney, Alan, Lind, Pehr, Glimelius, Bengt, Falk, Stephen, Izbicki, Jakob R, Middleton, Gary William, Cummins, Sebastian, Ross, Paul J, Wasan, Harpreet, McDonald, Alec, Crosby, Tom, Ma, Yuk Ting, Patel, Kinnari, Sherriff, David, Soomal, Rubin, Borg, David, Sothi, Sharmila, Hammel, Pascal, Hackert, Thilo, Jackson, Richard, and Büchler, Markus W

Published
2017
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16. Contributors

Author

Abou-Alfa, Ghassan K., primary, Abou Khalil, Jad, additional, Addeo, Pietro, additional, Adsay, N. Volkan, additional, Agarwal, Anil Kumar, additional, Alemi, Farzad, additional, Allen, Peter J., additional, Al-Mukhtar, Ahmed, additional, Aloia, Thomas A., additional, Andersen, Jesper B., additional, Anderson, Christopher D., additional, Arslan-Carlon, Vittoria, additional, Asbun, Horacio J., additional, Aussilhou, Béatrice, additional, Awad, Joseph, additional, Azoulay, Daniel, additional, Bachellier, Philippe, additional, Baker, Talia B., additional, Bamboat, Zubin M., additional, Barkun, Jeffrey Stewart, additional, Bassi, Claudio, additional, Basturk, Olca, additional, Beard, Rachel E., additional, Bedossa, Pierre, additional, Belghiti, Jacques, additional, Bellorin-Marin, Omar, additional, Besselink, Marc G.H., additional, Bilchik, Anton J., additional, Blumgart, Leslie H., additional, Boas, Franz Edward, additional, Brody, Lynn A., additional, Brown, Karen T., additional, Bruix, Jordi, additional, Bruno, David A., additional, Brunt, Elizabeth M., additional, Burns, Justin M., additional, Butturini, Giovanni, additional, Caicedo, Juan Carlos, additional, Callery, Mark P., additional, Calvino, Abdul Saied, additional, Carpenter, Danielle H., additional, Carter, C. Ross, additional, Cauchy, François, additional, Chan, Chung Yip, additional, Chan, See Ching, additional, Chapman, William C., additional, Cherqui, Daniel, additional, Cho, Clifford S., additional, Chung, Jin Wook, additional, Clanton, Jesse, additional, Clary, Bryan Marshall, additional, Cleary, Sean Patrick, additional, Collins, Kelly M., additional, Conneely, John Barry, additional, Connell, Louise C., additional, Corvera, Carlos U., additional, Costa, Guido, additional, Covey, Anne M., additional, Crippin, Jeffrey S., additional, Croome, Kristopher P., additional, Dabbous, Hany, additional, D'Angelica, Michael I., additional, Darcy, Michael D., additional, Davis, Jeremy L., additional, de Jonge, Jeroen, additional, DeMatteo, Ronald P., additional, DePeralta, Danielle K., additional, Desai, Niraj M., additional, de Santibañes, Eduardo, additional, de Santibañes, Martin, additional, Dickson, Euan J., additional, DiMaio, Christopher John, additional, Do, Richard Kinh Gian, additional, Dokmak, Safi, additional, Donati, Marcello, additional, Doyle, M.B. Majella, additional, Dudeja, Vikas, additional, Dunphy, Mark, additional, Earl, Truman M., additional, Ebata, Tomoki, additional, Dika, Imane El, additional, El-Gohary, Yousef, additional, Endo, Itaru, additional, Enestvedt, C. Kristian, additional, Espat, N. Joseph, additional, Ethun, Cecilia G., additional, Fan, Sheung Tat, additional, Fanta, Paul T., additional, Farges, Olivier, additional, Ferrone, Cristina R., additional, Fields, Ryan C., additional, Fischer, Mary, additional, Fisher, Sarah B., additional, Flaherty, Devin C., additional, Fong, Yuman, additional, Friedman, Scott L., additional, Gabr, Ahmed, additional, Galloway, John R., additional, Geller, David A., additional, Gerdes, Hans, additional, Gerst, Scott R., additional, Gittes, George K., additional, Glorioso, Jaime, additional, Gluskin, Jill S., additional, Goh, Brian K.P., additional, Gonzalez, Stevan A., additional, Goodman, Karyn A., additional, Gores, Gregory J., additional, Gotuzzo, Eduardo H., additional, Gouma, Dirk J., additional, Greig, Paul D., additional, Griffin, James F., additional, Halloran, Christopher M., additional, Halpern, Neil A., additional, Hammill, Chet W., additional, Hansen, Paul D., additional, Harding, James J., additional, M. Harrison, Ewen, additional, Hartwig, Werner, additional, Hasegawa, Kiyoshi, additional, Hechtman, Jaclyn F., additional, Heimbach, Julie K., additional, Helton, William S., additional, Hemming, Alan W., additional, Henderson, J. Michael, additional, Hirshberg, Asher, additional, Howe, James R., additional, Hughes, Christopher B., additional, Iacobuzio-Donahue, Christine, additional, Jarnagin, William R., additional, Jenkins, Roger L., additional, Jutric, Zeljka, additional, Kahlert, Christoph, additional, Kallini, Joseph Ralph, additional, Kangrga, Ivan, additional, Karanicolas, Paul J., additional, Katz, Seth S., additional, Katz, Steven C., additional, Kelly, Kaitlyn J., additional, Kemeny, Nancy E., additional, Kennedy, Eugene P., additional, Khalili, Korosh, additional, Khan, Adeel S., additional, Khan, Saboor, additional, Kim, Heung Bae, additional, Kingham, T. Peter, additional, Kirk, Allan D., additional, S. Klimstra, David, additional, Kluger, Michael, additional, Knechtle, Stuart J., additional, Koea, Jonathan B., additional, Kokudo, Norihiro, additional, Koliogiannis, Dionysios, additional, Kooby, David A., additional, Korenblat, Kevin, additional, Krebs, Simone, additional, LaQuaglia, Michael J., additional, LaQuaglia, Michael P., additional, LaRusso, Nicholas F., additional, Laurent, Alexis, additional, Lazaridis, Konstantinos N., additional, Leal, Julie N., additional, Lee, Eliza J., additional, Lee, Major Kenneth, additional, Lee, Ser Yee, additional, Lencioni, Riccardo, additional, Liccioni, Alexandre, additional, Lidsky, Michael E., additional, Lin, Chung-Wei, additional, Linehan, David C., additional, Lopez-Solis, Roberto Carlos, additional, Lowell, Jeffrey A., additional, Madoff, David C., additional, Maggi, Jason, additional, Maithel, Shishir K., additional, Majeed, Ali W., additional, Malfertheiner, Peter, additional, Malleo, Giuseppe, additional, Mao, Shennen A., additional, Marchegiani, Giovanni, additional, Marcos, Luis A., additional, Markmann, James F., additional, Marsh, J. Wallis, additional, Martin, Robert C.G., additional, Matsuyama, Ryusei, additional, Matter, Matthias S., additional, Mattera, Francisco Juan, additional, Maxwell, Jessica E., additional, Mazza, Oscar M., additional, McGilvray, Ian D., additional, McKay, Colin J., additional, McWeeney, Doireann M., additional, Melendez, Jose, additional, Mendelsohn, Robin B., additional, Miller, George, additional, Mönkemüller, Klaus E., additional, Mori, Ryutaro, additional, Moutinho, Vitor, additional, Nagino, Masato, additional, Nagorney, David M., additional, Nagula, Satish, additional, Nakeeb, Attila, additional, Nedredal, Geir I., additional, Neoptolemos, John P., additional, Neuberger, James, additional, Nyberg, Scott L., additional, O'Connor, Rachel, additional, O'Grady, John G., additional, Oldfield, Frances E., additional, Oldhafer, Karl J., additional, Olthoff, Kim M., additional, Orloff, Susan L., additional, Paniccia, Alessandro, additional, Paradis, Valérie, additional, Parks, Rowan W., additional, Pascal, Gérard, additional, Pastores, Stephen M., additional, Pawlik, Timothy M., additional, Pillarisetty, Venu G., additional, Pingpank, James Francis, additional, Pinson, C. Wright, additional, Pitt, Henry Anthony, additional, Pomposelli, James J., additional, Procopio, Fabio, additional, Pucci, Michael J., additional, Qadan, Motaz, additional, Rajkomar, Kheman, additional, Reddy, Srinevas K., additional, Reig, Maria E., additional, Reza, Joseph Arturo, additional, Roberts, John Paul, additional, Robson, Piera Marie Cote, additional, Rocha, Flavio G., additional, Roll, Garrett Richard, additional, Ronnekleiv-Kelly, Sean M., additional, Rosemurgy, Alexander S., additional, Rosen, Charles B., additional, Saldinger, Pierre F., additional, Salem, Riad, additional, Salem, Suhail Bakr, additional, Salvia, Roberto, additional, Sandroussi, Charbel, additional, Sanford, Dominic E., additional, Scatton, Olivier, additional, Schattner, Mark Andrew, additional, Schecter, William Palmer, additional, Schoellhammer, Hans Francis, additional, Schulick, Richard D., additional, Schwartz, Lawrence H., additional, Shah, Kevin N., additional, Shepherd, Ross W., additional, Shimada, Hiroshi, additional, Shimoda, Masafumi, additional, Shindoh, Junichi, additional, Shokouh-Amiri, Hosein, additional, Sicklick, Jason K., additional, Siegelbaum, Robert H., additional, Singh, Gagandeep, additional, Smoot, Rory L., additional, Solomon, Stephen B., additional, Soubrane, Olivier, additional, Spinelli, Nicholas, additional, Stauffer, John A., additional, Stewart, Lygia, additional, Strand, Matthew S., additional, Tabibian, James H., additional, Torzilli, Guido, additional, Trotter, James F., additional, Turcotte, Simon, additional, Turmelle, Yumirle P., additional, Tzimas, Demetrios J., additional, Van Gulik, Thomas, additional, Vannucci, Andrea, additional, Vauthey, Jean-Nicolas, additional, Vetter, Diana, additional, Vilgrain, Valérie, additional, Villamil, Alejandra Maria, additional, Voigt, Louis P., additional, Vollmer, Charles M., additional, Wands, Jack R., additional, Wattacheril, Julia, additional, Weber, Sharon Marie, additional, Weiss, Matthew J., additional, Weitz, Jürgen, additional, Werner, Jens, additional, Winner, Megan, additional, Wong, John, additional, Yang, Dennis, additional, Yarmohammadi, Hooman, additional, Yeo, Charles J., additional, Yeo, Theresa Pluth, additional, Yoon, Chang Jin, additional, Yopp, Adam, additional, Young, D. Owen, additional, Zhao, Kai, additional, Zibari, Gazi B., additional, and Zogopoulos, George, additional

Published
2017
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17. A Multicenter, Randomized, Double-Blinded, Clinical Trial Comparing Cattell-Warren and Blumgart Anastomoses Following Partial Pancreatoduodenectomy

Author

Halloran, Christopher M., primary, Neoptolemos, John P., additional, Jackson, Richard, additional, Platt, Kellie, additional, Psarelli, Eftychia-Eirini, additional, Reddy, Srikanth, additional, Gomez, Dhanwant, additional, O’Reilly, Derek A., additional, Smith, Andrew, additional, Pausch, Thomas M., additional, Prachalias, Andreas, additional, Davidson, Brian, additional, and Ghaneh, Paula, additional

Published
2022
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19. Diagnosis and treatment of exocrine pancreatic insufficiency in chronic pancreatitis: An international expert survey and case vignette study

Author

de Rijk, Florence E.M., primary, van Veldhuisen, Charlotte L., additional, Besselink, Marc G., additional, van Hooft, Jeanin E., additional, van Santvoort, Hjalmar C., additional, van Geenen, Erwin J.M., additional, Hegyi, Peter, additional, Löhr, J-Matthias, additional, Dominguez-Munoz, Juan E., additional, de Jonge, Pieter Jan F., additional, Bruno, Marco J., additional, Verdonk, Robert C., additional, Falconi, Massimo, additional, Zou, Wen-Bin, additional, Engjom, Trond, additional, Ooi, Chee Y., additional, Sutton, Robert, additional, Frulloni, Luca, additional, Neoptolemos, John, additional, Wilcox, Charles, additional, Miroslav, Vujasinovic, additional, Trikudanathan, Guru, additional, Liao, Zhuan, additional, Hauge, Truls, additional, Mössner, Joachim, additional, Hoge, Chantal, additional, Fockens, Paul, additional, Mieog, Sven, additional, Capurso, Gabriele, additional, Cui, Yunfeng, additional, de Madaria, Enrique, additional, Distler, Marius, additional, Aghdassi, Ali, additional, Whitcomb, David C., additional, Russell, Kylie, additional, Beyer, Georg, additional, Kunovsky, Lumír, additional, Kwanten, Wilhelmus, additional, Nava, Andrea Kazemi, additional, Conlon, Kevin, additional, Siriwardena, A.K., additional, Paiella, Salvatore, additional, Alconchel, Felipe, additional, Marino, Marco Vito, additional, de Meijer, Vincent E., additional, Domingo, Carlos, additional, Kleeff, Jorg, additional, Lakshmanan, Aarti, additional, Lie Chu, Michael Jen, additional, Bouwense, Stefan, additional, Nashidengo, Pueya Rashid, additional, Konstantinos, Perivoliotis, additional, Muttillo, Edoardo Maria, additional, Umar, Garzali Ibrahim, additional, Castro Santiago, Maria Jesus, additional, Lopez-Lopez, Victor, additional, Torri, Francesco, additional, Schmelzle, Moritz, additional, Ignatavicius, Povilas, additional, Wicherts, Dennis, additional, Gomes, Antonio, additional, Machairas, Nikolaos A., additional, Dorovinis, Panagiotis I., additional, Serrablo, Alejandro, additional, Soreide, Kjetil, additional, Rahbari, Mohammad, additional, Jie Chu, Michael Jen, additional, Ptasnuka, Margarita, additional, Petrulionis, Marius, additional, Noel, Colin Byron, additional, Castro, Ernest, additional, Di Martino, Marcello, additional, Recordare, Alfonso, additional, Stättner, Stefan, additional, Ausania, Fabio, additional, Hartman, Vera, additional, Roeyen, Geert, additional, Egorov, Viacheslav, additional, Vanagas, Tomas, additional, Ebrahim, Mohamed, additional, Arabadzhieva, Elena, additional, Malleo, Giuseppe, additional, Li, Liang, additional, Adams, David, additional, Oracz, Grzegorz, additional, Nageshwar, Reddy D., additional, Waldthaler, Alexander, additional, Masamune, Atsushi, additional, Drewes, Asbjorn Mohr, additional, Amodio, Antonio, additional, Tirkes, Temel, additional, Srivastava, Anshu, additional, Beilman, Gregory J., additional, Berger, Zoltan, additional, Lindkvist, Bjorn, additional, Cavestro, Giulia Martina, additional, Gariepy, Cheryl, additional, Czakó, Laszlo, additional, Di Leo, Milena, additional, Sharma, Vishal, additional, Lakhtakia, Sundeep, additional, Rana, Surinder Singh, additional, Duggan, Sinaed N., additional, Kwon, Chang-Il, additional, Phillips, Anna Evans, additional, Forsmark, Christopher E., additional, Gleeson, Ferga C., additional, Lehman, Glen A., additional, Greenhalf, William, additional, Costamagna, Guido, additional, Halloran, Christopher M., additional, Friess, Helmut, additional, Rasmussen, Henrik Hojgaard, additional, Ikeura, Tsukasa, additional, Haldorsen, Ingfrid S., additional, Itoi, Takao, additional, Izbicki, Jacob R., additional, Windsor, John, additional, Poulsen, Jakob Lykke, additional, Frokjaer, Jens Brondum, additional, Larino-Noia, Jose, additional, Wang, Dan, additional, Garcia, Julio Iglesias, additional, Kalaitzakis, Evangelos, additional, Wertheim-Tysarowska, Kararzyna, additional, Kubota, Kensuke, additional, Larusch, Jessica, additional, Lerch, Markus M., additional, Hu, Liang-Hao, additional, Erkan, Mert, additional, Machicado, Jorg D., additional, Arvanitakis, Marianna, additional, Buchler, Markus W., additional, Levy, Marlon F., additional, Heyman, Melvin B., additional, Nojgaard, Camilla, additional, Khashab, Mouen A., additional, Delhaye, Myriam, additional, Ogura, Takeshi, additional, Okazaki, Kazuichi, additional, Ghaneh, Paula, additional, Banks, Peter A., additional, Gupta, Pankaj, additional, Papachristou, Georgios I., additional, Michl, Patrick, additional, Levy, Philippe, additional, Pukitis, Aldis, additional, Pezzilli, Raffaele, additional, Baron, Ryan D., additional, Amann, Stephen T., additional, Schwarzenberg, Sarah Jane, additional, Isaji, Shuiji, additional, Olesen, Soren Schou, additional, Novovic, Srdan, additional, Hughes, Steven J., additional, Werlin, Steven L., additional, Gonska, Tanja, additional, Gardner, Timothy B., additional, Topazian, Mark D., additional, Weiss, Frank Ulrich, additional, Akshintala, Venakata S., additional, Morinville, Veronique D., additional, Rebours, Vinciane, additional, Vincze, Aron, additional, Singh, Vikesh K., additional, Cui, Naiqiang, additional, Zhang, Hong, additional, and Li, Zhao-shen, additional

Published
2022
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21. Pancreatic cancer

Author

Weitz, Jürgen, primary, Büchler, Markus W., additional, Sykes, Paul D., additional, Neoptolemos, John P., additional, Costello, Eithne, additional, Halloran, Christopher M., additional, Bergmann, Frank, additional, Schirmacher, Peter, additional, Bork, Ulrich, additional, Fritz, Stefan, additional, Werner, Jens, additional, Brunner, Thomas, additional, Smyth, Elizabeth, additional, Cunningham, David, additional, Untch, Brian R., additional, and Allen, Peter J., additional

Published
2016
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23. Chemotherapy-induced infiltration of neutrophils promotes pancreatic cancer metastasis via Gas6/AXL signalling axis

Author

Bellomo, Gaia, primary, Rainer, Carolyn, additional, Quaranta, Valeria, additional, Astuti, Yuliana, additional, Raymant, Meirion, additional, Boyd, Elzbieta, additional, Stafferton, Ruth, additional, Campbell, Fiona, additional, Ghaneh, Paula, additional, Halloran, Christopher M, additional, Hammond, Dean E, additional, Morton, Jennifer P, additional, Palmer, Daniel, additional, Vimalachandran, Dale, additional, Jones, Robert, additional, Mielgo, Ainhoa, additional, and Schmid, Michael C, additional

Published
2022
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24. Pancreatic Cancer hENT1 Expression and Survival From Gemcitabine in Patients From the ESPAC-3 Trial

Author

Greenhalf, William, Ghaneh, Paula, Neoptolemos, John P., Palmer, Daniel H., Cox, Trevor F., Lamb, Richard F., Garner, Elizabeth, Campbell, Fiona, Mackey, John R., Costello, Eithne, Moore, Malcolm J., Valle, Juan W., McDonald, Alexander C., Carter, Ross, Tebbutt, Niall C., Goldstein, David, Shannon, Jennifer, Dervenis, Christos, Glimelius, Bengt, Deakin, Mark, Charnley, Richard M., Lacaine, François, Scarfe, Andrew G., Middleton, Mark R., Anthoney, Alan, Halloran, Christopher M., Mayerle, Julia, Oláh, Attila, Jackson, Richard, Rawcliffe, Charlotte L., Scarpa, Aldo, Bassi, Claudio, and Büchler, Markus W.

Published
2014
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25. Postpancreatectomy Acute Pancreatitis (PPAP)

Author

Marchegiani, Giovanni, Barreto, Savio George, Bannone, Elisa, Sarr, Michael, Vollmer, Charles M, Connor, Saxon, Falconi, Massimo, Besselink, Marc G, Salvia, Roberto, Wolfgang, Christopher L, Zyromski, Nicholas J, Yeo, Charles J, Adham, Mustapha, Siriwardena, Ajith K, Takaori, Kyoichi, Hilal, Mohammad Abu, Loos, Martin, Probst, Pascal, Hackert, Thilo, Strobel, Oliver, Busch, Olivier RC, Lillemoe, Keith D, Miao, Yi, Halloran, Christopher M, Werner, Jens, Friess, Helmut, Izbicki, Jakob R, Bockhorn, Maximillian, Vashist, Yogesh K, Conlon, Kevin, Passas, Ioannis, Gianotti, Luca, Del Chiaro, Marco, Schulick, Richard D, Montorsi, Marco, Oláh, Attila, Fusai, Giuseppe Kito, Serrablo, Alejandro, Zerbi, Alessandro, Fingerhut, Abe, Andersson, Roland, Padbury, Robert, Dervenis, Christos, Neoptolemos, John P, Bassi, Claudio, Büchler, Markus W, and Shrikhande, Shailesh V

Published
2021

26. hENT1 Predicts Benefit from Gemcitabine in Pancreatic Cancer but Only with Low CDA mRNA

Author

Aughton, Karen, primary, Elander, Nils O., additional, Evans, Anthony, additional, Jackson, Richard, additional, Campbell, Fiona, additional, Costello, Eithne, additional, Halloran, Christopher M., additional, Mackey, John R., additional, Scarfe, Andrew G., additional, Valle, Juan W., additional, Carter, Ross, additional, Cunningham, David, additional, Tebbutt, Niall C., additional, Goldstein, David, additional, Shannon, Jennifer, additional, Glimelius, Bengt, additional, Hackert, Thilo, additional, Charnley, Richard M., additional, Anthoney, Alan, additional, Lerch, Markus M., additional, Mayerle, Julia, additional, Palmer, Daniel H., additional, Büchler, Markus W., additional, Ghaneh, Paula, additional, Neoptolemos, John P., additional, and Greenhalf, William, additional

Published
2021
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27. SARS-CoV-2 infection is associated with an increased risk of idiopathic acute pancreatitis but not pancreatic exocrine insufficiency or diabetes: long-term results of the COVIDPAN study

Author

Nayar, Manu, primary, Varghese, Chris, additional, Kanwar, Aditya, additional, Siriwardena, Ajith K, additional, Haque, Ali Raza, additional, Awan, Altaf, additional, Balakrishnan, Anita, additional, Rawashdeh, Arab, additional, Ivanov, Bogdan, additional, Parmar, Chetan, additional, Halloran, Christopher M, additional, Caruana, Clifford, additional, Borg, Cynthia-Michelle, additional, Gomez, Dhanny, additional, Damaskos, Dimitrios, additional, Karavias, Dimitrios, additional, Finch, Guy, additional, Ebied, Husam, additional, Pine, James K, additional, Skipworth, James R A, additional, Milburn, James, additional, Latif, Javed, additional, Apollos, Jeyakumar, additional, El Kafsi, Jihène, additional, Windsor, John A, additional, Roberts, Keith, additional, Wang, Kelvin, additional, Ravi, Krish, additional, Coats, Maria V, additional, Hollyman, Marianne, additional, Phillips, Mary, additional, Okocha, Michael, additional, Wilson, Michael SJ, additional, Ameer, Nadeem A, additional, Kumar, Nagappan, additional, Shah, Nehal, additional, Lapolla, Pierfrancesco, additional, Magee, Connor, additional, Al-Sarireh, Bilal, additional, Lunevicius, Raimundas, additional, Benhmida, Rami, additional, Singhal, Rishi, additional, Balachandra, Srinivasan, additional, Demirli Atıcı, Semra, additional, Jaunoo, Shameen, additional, Dwerryhouse, Simon, additional, Boyce, Tamsin, additional, Charalampakis, Vasileios, additional, Kanakala, Venkat, additional, Abbas, Zaigham, additional, Tewari, Nilanjana, additional, and Pandanaboyana, Sanjay, additional

Published
2021
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29. hENT1 Predicts Benefit from Gemcitabine in Pancreatic Cancer but Only with Low CDA mRNA

Author

Aughton, Karen, Elander, Nils O., Evans, Anthony, Jackson, Richard, Campbell, Fiona, Costello, Eithne, Halloran, Christopher M., Mackey, John R., Scarfe, Andrew G., Valle, Juan W., Carter, Ross, Cunningham, David, Tebbutt, Niall C., Goldstein, David, Shannon, Jennifer, Glimelius, Bengt, Hackert, Thilo, Charnley, Richard M., Anthoney, Alan, Lerch, Markus M., Mayerle, Julia, Palmer, Daniel H., Büchler, Markus W., Ghaneh, Paula, Neoptolemos, John P., Greenhalf, William, Aughton, Karen, Elander, Nils O., Evans, Anthony, Jackson, Richard, Campbell, Fiona, Costello, Eithne, Halloran, Christopher M., Mackey, John R., Scarfe, Andrew G., Valle, Juan W., Carter, Ross, Cunningham, David, Tebbutt, Niall C., Goldstein, David, Shannon, Jennifer, Glimelius, Bengt, Hackert, Thilo, Charnley, Richard M., Anthoney, Alan, Lerch, Markus M., Mayerle, Julia, Palmer, Daniel H., Büchler, Markus W., Ghaneh, Paula, Neoptolemos, John P., and Greenhalf, William

Abstract

Gemcitabine or 5-fluorouracil (5-FU) based treatments can be selected for pancreatic cancer. Equilibrative nucleoside transporter 1 (hENT1) predicts adjuvant gemcitabine treatment benefit over 5-FU. Cytidine deaminase (CDA), inside or outside of the cancer cell, will deaminate gemcitabine, altering transporter affinity. ESPAC-3(v2) was a pancreatic cancer trial comparing adjuvant gemcitabine and 5-FU. Tissue microarray sections underwent in situ hybridization and immunohistochemistry. Analysis of both CDA and hENT1 was possible with 277 patients. The transcript did not correlate with protein levels for either marker. High hENT1 protein was prognostic with gemcitabine; median overall survival was 26.0 v 16.8 months (p = 0.006). Low CDA transcript was prognostic regardless of arm; 24.8 v 21.2 months with gemcitabine (p = 0.02) and 26.4 v 14.6 months with 5-FU (p = 0.02). Patients with low hENT1 protein did better with 5-FU, but only if the CDA transcript was low (median survival of 5-FU v gemcitabine; 29.3 v 18.3 months, compared with 14.2 v 14.6 with high CDA). CDA mRNA is an independent prognostic biomarker. When added to hENT1 protein status, it may also provide treatment-specific predictive information and, within the frame of a personalized treatment strategy, guide to either gemcitabine or 5FU for the individual patient. Simple Summary: Recent clinical trials suggest that combination therapies that include either gemcitabine or 5-fluorouracil (5-FU) both give significant survival benefits for pancreatic cancer patients. The tumor level of the nucleoside transporter hENT1 is prognostic in patients treated with adjuvant gemcitabine but not adjuvant 5-FU. This work shows for the first time that hENT1 is only predictive of benefit from gemcitabine over 5-FU in patients with low levels of CDA transcript. A choice between adjuvant 5-FU based combination therapies (such as FOLFIRINOX) and gemcitabine-based therapy (e.g., GemCap) could be made based on a combination of

Published
2021
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30. SARS-CoV-2 infection is associated with an increased risk of idiopathic acute pancreatitis but not pancreatic exocrine insufficiency or diabetes: long-term results of the COVIDPAN study.

Author

Nayar, Manu, Varghese, Chris, Kanwar, Aditya, Siriwardena, Ajith K., Haque, Ali Raza, Awan, Altaf, Balakrishnan, Anita, Rawashdeh, Arab, Ivanov, Bogdan, Parmar, Chetan, Halloran, Christopher M., Caruana, Clifford, Borg, Cynthia-Michelle, Gomez, Dhanny, Damaskos, Dimitrios, Karavias, Dimitrios, Finch, Guy, Ebied, Husam, Pine, James K., and Skipworth, James R. A.

Subjects
EXOCRINE pancreatic insufficiency, ENDOSCOPIC retrograde cholangiopancreatography, FECAL microbiota transplantation, PANCREATITIS
Published
2022
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33. Contributors

Author

Abou-Alfa, Ghassan K., primary, Adsay, N. Volkan, additional, Akhurst, Timothy, additional, Alemi, Farzad, additional, Allegra, David, additional, Allen, Peter J., additional, Anderson, Christopher D., additional, Aoki, Taku, additional, Arulraj, Ramakrishnan, additional, Auer, Rebecca Ann C., additional, Aussilhou, Béatrice, additional, Awad, Joseph, additional, Ball, Chad G., additional, Bamboat, Zubin M., additional, Bassi, Claudio, additional, Becker, Christoph D., additional, Bedossa, Pierre, additional, Belghiti, Jacques, additional, Belletrutti, Paul, additional, Bilchik, Anton J., additional, Blumgart, Leslie H., additional, Bornman, Philippus C., additional, Boutros, Cherif, additional, Brody, Jonathan R., additional, Brody, Lynn A., additional, Brouquet, Antoine, additional, Brown, Karen T., additional, Brugge, William R., additional, Bruix, Jordi, additional, Bruno, David A., additional, Brunt, Elizabeth M., additional, Büchler, Markus W., additional, Burns, Justin M., additional, Butturini, Giovanni, additional, Callery, Mark P., additional, Carr-Locke, David L., additional, Cha, Charles, additional, Chan, See Ching, additional, Chapman, William C., additional, Cherqui, Daniel, additional, Cho, Clifford S., additional, Chung, Jin Wook, additional, Clary, Bryan, additional, Cocieru, Andrei, additional, Contreras, Carlos M., additional, Conzen, Kendra D., additional, Corvera, Carlos U., additional, Covey, Anne M., additional, Crippin, Jeffrey S., additional, Dabbous, Hany, additional, D’Angelica, Michael I., additional, Darcy, Michael, additional, Davenport, Mark, additional, De Jonge, Jeroen, additional, DeMatteo, Ronald P., additional, Demetriou, Achilles A., additional, Desai, Niraj M., additional, De Santibañes, Eduardo, additional, Desser, Terry S., additional, Dhanireddy, Kiran K., additional, Dokmak, Safi, additional, Doyle, M.B. Majella, additional, Earl, Truman M., additional, Ebata, Tomoki, additional, El-Gohary, Yousef, additional, Epstein, Andrew S., additional, Espat, N. Joseph, additional, Fan, Sheung Tat, additional, Farges, Olivier, additional, Fernandez-Del Castillo, Carlos, additional, Ferrone, Cristina R., additional, Fischer, Mary, additional, Fisher, James E., additional, Fong, Yuman, additional, Forner, Alejandro, additional, Friedman, Scott L., additional, Fritz, Stefan, additional, Galloway, John R., additional, Gerdes, Hans, additional, Getrajdman, George, additional, Ghaneh, Paula, additional, Ghittoni, Giorgia, additional, Gittes, George, additional, Goodman, Karyn A., additional, Gores, Gregory J., additional, Gotuzzo, Eduardo, additional, Gouma, Dirk J., additional, Greig, Paul D., additional, Halloran, Christopher M., additional, Halpern, Neil A., additional, Hann, Lucy E., additional, Harrison, Ewen M., additional, Hartwig, Werner, additional, Heimbach, Julie K., additional, Helton, William S., additional, Hemming, Alan W., additional, Henderson, J. Michael, additional, Hessheimer, Amelia J., additional, Hirshberg, Asher, additional, Ho, Alice, additional, House, Michael G., additional, Hsieh, Chung-Bao, additional, Hsu, Kuo-Feng, additional, Iannitti, David A., additional, Imamura, Hiroshi, additional, Imrie, Clem W., additional, Jarnagin, William R., additional, Jenkins, Roger L., additional, Kahl, Stefan, additional, Kangrga, Ivan, additional, Kelly, Kaitlyn, additional, Kemeny, Nancy E., additional, Kennedy, Eugene P., additional, Kerlan Jr, Robert K., additional, Khan, Adeel S., additional, Khan, Saboor, additional, Kingham, T. Peter, additional, Kirk, Allan D., additional, Kitagawa, Yuichi, additional, Klimstra, David S., additional, Kluger, Michael D., additional, Knechtle, Stuart J., additional, Kneuertz, Peter J., additional, Koea, Jonathan, additional, Koffron, Alan J., additional, Kokudo, Norihiro, additional, Kooby, David A., additional, Korenblat, Kevin, additional, Krasny, Robert M., additional, Krige, Jake, additional, Kurtz, Robert C., additional, Landman, Matthew P., additional, La Quaglia, Michael P., additional, LaRusso, Nicholas F., additional, Lau, Kwan N., additional, Lazaridis, Konstantinos N., additional, Lerch, Markus M., additional, Lillegard, Joseph B., additional, Lillemoe, Keith D., additional, Linehan, David C., additional, Logan, Susan, additional, Loveday, Benjamin, additional, Lowell, Jeffrey A., additional, Madoff, David C., additional, Maithel, Shishir K., additional, Majeed, Ali W., additional, Makuuchi, Masatoshi, additional, Malfertheiner, Peter, additional, Mamlouk, Mark, additional, Marchegiani, Giovanni, additional, Marcos, Luis A., additional, Markmann, James F., additional, Marsh, J. Wallis, additional, Martin, Maureen, additional, Martin II, Robert C.G., additional, Maru, Dipen M., additional, Mattera, Francisco Juan, additional, Mayerle, Julia V., additional, Mazza, Oscar M., additional, McGilvray, Ian D., additional, McKay, Colin J., additional, Melendez, Jose A., additional, Mezhir, James J., additional, Miller, George, additional, Mönkemüller, Klaus, additional, Moo-Young, Tricia A., additional, Nadig, Satish N., additional, Nagino, Masato, additional, Nagle, Alexander, additional, Nagorney, David M., additional, Nakeeb, Atilla, additional, Nazario, Hector E., additional, Nedredal, Geir, additional, Neoptolemos, John P., additional, Neuberger, James, additional, Nguyen, Douglas L., additional, Nimura, Yuji, additional, Nyberg, Scott L., additional, O’Grady, John G., additional, O’laoide, Risteard, additional, Olthoff, Kim Marie, additional, Orloff, Mark S., additional, Orloff, Marshall J., additional, Orloff, Susan L., additional, Pai, Rish K., additional, Papalezova, Katia, additional, Paradis, Valérie, additional, Parks, Rowan W., additional, Passik, Steven D., additional, Pastores, Stephen M., additional, Pessaux, Patrick, additional, Petrov, Maxim S., additional, Pillarisetty, Venu G., additional, Pingpank Jr, James, additional, Pinson, C. Wright, additional, Pitka, Sofija, additional, Pitt, Henry A., additional, Pomposelli, James J., additional, Pratt, Wande B., additional, Prinz, Richard A., additional, Puli, Srinivas R., additional, Que, Florencia G., additional, Ravetta, Valentina, additional, Reig, Maria E., additional, Riaz, Ahsun, additional, Rich, Barrie S., additional, Rittenhouse, David W., additional, Roberts, John, additional, Robson, Piera, additional, Rocha, Flavio G., additional, Roddenbery V, Seaborn A., additional, Rodriguez de Lopes, Carlos, additional, Roll, Garrett R., additional, Rosemurgy II, Alex S., additional, Rosen, Charles B., additional, Rossi, Sandro, additional, Saldinger, Pierre F., additional, Salem, Riad, additional, Saltz, Leonard B., additional, Sanchez, Norberto J., additional, Sandroussi, Charbel, additional, Sano, Tsuyoshi, additional, Scatton, O., additional, Schattner, Mark, additional, Schecter, William P., additional, Schiffman, Suzanne C., additional, Schmidt, C. Max, additional, Schoellnast, Helmut, additional, Schwartz, Lawrence H., additional, Shepherd, Ross W., additional, Shimoda, Masafumi, additional, Shokouh-Amiri, Hosein, additional, Siddiqi, Nasir H., additional, Solomon, Stephen B., additional, Soper, Nathaniel J., additional, Starzl, Thomas E., additional, Steer, Michael, additional, Stewart, Lygia, additional, Strobel, Oliver, additional, Teitcher, Jerrold, additional, Terashima, Angélica, additional, Terraz, Sylvain, additional, Thomas, William E.G., additional, Torzilli, Guido, additional, Trotter, James F., additional, Turmelle, Yumirle P., additional, Van Cott, Christine, additional, Vannucci, Andrea, additional, vanSonnenberg, Eric, additional, Vauthey, Jean-Nicolas, additional, Vetter, Diana, additional, Vilgrain, Valerie, additional, Villamil, Alejandra, additional, Voigt, Louis, additional, Vollmer Jr, Charles M., additional, Wands, Jack R., additional, Wattacheril, Julia, additional, Weber, Sharon, additional, Weiss, Matthew, additional, Weitz, Jürgen, additional, Werner, Jens, additional, Wheatley, Antony M., additional, Windsor, John A., additional, Winston, Corinne, additional, Winter, Jordan, additional, Witkiewicz, Agnieszka K., additional, Wong, John, additional, Yeo, Charles J., additional, Yeo, Theresa P., additional, Yoon, Chang Jin, additional, Yopp, Adam, additional, Zibari, Gazi, additional, and Zuckerman, Randall, additional

Published
2012
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34. Effect of Adjuvant Chemotherapy With Fluorouracil Plus Folinic Acid or Gemcitabine vs Observation on Survival in Patients With Resected Periampullary Adenocarcinoma: The ESPAC-3 Periampullary Cancer Randomized Trial

Author

Neoptolemos, John P., Moore, Malcolm J., Cox, Trevor F., Valle, Juan W., Palmer, Daniel H., McDonald, Alexander C., Carter, Ross, Tebbutt, Niall C., Dervenis, Christos, Smith, David, Glimelius, Bengt, Charnley, Richard M., Lacaine, François, Scarfe, Andrew G., Middleton, Mark R., Anthoney, Alan, Ghaneh, Paula, Halloran, Christopher M., Lerch, Markus M., Oláh, Attila, Rawcliffe, Charlotte L., Verbeke, Caroline S., Campbell, Fiona, and Büchler, Markus W.

Published
2012
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38. Patterns of Recurrence After Resection of Pancreatic Ductal Adenocarcinoma: A Secondary Analysis of the ESPAC-4 Randomized Adjuvant Chemotherapy Trial

Author

Jones, Robert P, Psarelli, Eftychia-Eirini, Jackson, Richard, Ghaneh, Paula, Halloran, Christopher M, Palmer, Daniel H, Campbell, Fiona, Valle, Juan W, Faluyi, Olusola, O'Reilly, Derek A, Cunningham, David, Wadsley, Jonathan, Darby, Suzanne, Meyer, Tim, Gillmore, Roopinder, Anthoney, Alan, Lind, Pehr, Glimelius, Bengt, Falk, Stephen, Izbicki, Jakob R, Middleton, Gary William, Cummins, Sebastian, Ross, Paul J, Wasan, Harpreet, McDonald, Alec, Crosby, Tom, Ting, Yuk, Patel, Kinnari, Sherriff, David, Soomal, Rubin, Borg, David, Sothi, Sharmila, Hammel, Pascal, Lerch, Markus M, Mayerle, Julia, Tjaden, Christine, Strobel, Oliver, Hackert, Thilo, Buchler, Markus W, Neoptolemos, John P, Hill, Mark, Corrie, Pippa, Hickish, Tamas, Napier, Mark, Slater, Sarah, Valle, Juan, Shablak, Alaaeldin, Cunnell, Michelle, Guimbaud, Rosine, Roques, Tom, Iveson, Tim, Jamil, Arshad, Robinson, Angus, Garcia-Alonso, Angel, Chang, David, Tsang, David, Wadd, Nick, Wall, Lucy, Nielsen, Niels Hilmer, Lerch, Markus, Mehta, Ajay, Sivaramalingam, Muthiah, Fyfe, David, Osborne, Richard, Blesing, Claire, Bulusu, Venkata Ramesh, Rathbone, Emma, Seitz, Jean-Francois, Beaumont, Erica, Dernedde, Ulrike, McAdam, Karen, Dimopoulos, Prokopios, Cominos, Mathilda, Askill, Colin, Piwowar, Andrzej, Bachet, Jean-Baptiste, Sumpter, Kate, Raouf, Sherif, Nicoll, Jonathan, Rees, Charlotte, Dhinakaran, Kathirvelu, Haux, Johan, Bengrine-Lefevre, Leila, Terrebonne, Eric, Shankland, Catherine, Palmer, Cheryl, Medley, Louise, Toy, Elizabeth, Kaur, Jasvinder, Gupta, Kamalnayan, Cheeseman, Sue, Patterson, Daniel, Candish, Charles, Thompson, Joyce, Coxon, Fareeda, Connolly, Caroline, McPhail, Neil, Williams, Rachel, Flygare, Petra, Elmlund, Mattias, Artru, Pascal, Millat, Bertrand, and Canc, European Study Grp Pancreatic

Subjects
medicine.medical_specialty, Chemotherapy, Randomization, business.industry, medicine.medical_treatment, 030230 surgery, medicine.disease, Gastroenterology, Gemcitabine, law.invention, Capecitabine, 03 medical and health sciences, 0302 clinical medicine, Randomized controlled trial, law, 030220 oncology & carcinogenesis, Internal medicine, Pancreatic cancer, medicine, Carcinoma, Surgery, Prospective cohort study, business, medicine.drug
Abstract

Importance The patterns of disease recurrence after resection of pancreatic ductal adenocarcinoma with adjuvant chemotherapy remain unclear. Objective To define patterns of recurrence after adjuvant chemotherapy and the association with survival. Design, Setting, and Participants Prospectively collected data from the phase 3 European Study Group for Pancreatic Cancer 4 adjuvant clinical trial, an international multicenter study. The study included 730 patients who had resection and adjuvant chemotherapy for pancreatic cancer. Data were analyzed between July 2017 and May 2019. Interventions Randomization to adjuvant gemcitabine or gemcitabine plus capecitabine. Main Outcomes and Measures Overall survival, recurrence, and sites of recurrence. Results Of the 730 patients, median age was 65 years (range 37-81 years), 414 were men (57%), and 316 were women (43%). The median follow-up time from randomization was 43.2 months (95% CI, 39.7-45.5 months), with overall survival from time of surgery of 27.9 months (95% CI, 24.8-29.9 months) with gemcitabine and 30.2 months (95% CI, 25.8-33.5 months) with the combination (HR, 0.81; 95% CI, 0.68-0.98;P = .03). The 5-year survival estimates were 17.1% (95% CI, 11.6%-23.5%) and 28.0% (22.0%-34.3%), respectively. Recurrence occurred in 479 patients (65.6%); another 78 patients (10.7%) died without recurrence. Local recurrence occurred at a median of 11.63 months (95% CI, 10.05-12.19 months), significantly different from those with distant recurrence with a median of 9.49 months (95% CI, 8.44-10.71 months) (HR, 1.21; 95% CI, 1.01-1.45;P = .04). Following recurrence, the median survival was 9.36 months (95% CI, 8.08-10.48 months) for local recurrence and 8.94 months (95% CI, 7.82-11.17 months) with distant recurrence (HR, 0.89; 95% CI, 0.73-1.09;P = .27). The median overall survival of patients with distant-only recurrence (23.03 months; 95% CI, 19.55-25.85 months) or local with distant recurrence (23.82 months; 95% CI, 17.48-28.32 months) was not significantly different from those with only local recurrence (24.83 months; 95% CI, 22.96-27.63 months) (P = .85 andP = .35, respectively). Gemcitabine plus capecitabine had a 21% reduction of death following recurrence compared with monotherapy (HR, 0.79; 95% CI, 0.64-0.98;P = .03). Conclusions and Relevance There were no significant differences between the time to recurrence and subsequent and overall survival between local and distant recurrence. Pancreatic cancer behaves as a systemic disease requiring effective systemic therapy after resection. Trial Registration ClinicalTrials.gov identifier:NCT00058201, EudraCT 2007-004299-38, and ISRCTN 96397434.

Published
2019

39. Patterns of Recurrence After Resection of Pancreatic Ductal Adenocarcinoma : A Secondary Analysis of the ESPAC-4 Randomized Adjuvant Chemotherapy Trial

Author

Jones, Robert P., Psarelli, Eftychia-Eirini, Jackson, Richard, Ghaneh, Paula, Halloran, Christopher M., Palmer, Daniel H., Campbell, Fiona, Valle, Juan W., Faluyi, Olusola, O'Reilly, Derek A., Cunningham, David, Wadsley, Jonathan, Darby, Suzanne, Meyer, Tim, Gillmore, Roopinder, Anthoney, Alan, Lind, Pehr, Glimelius, Bengt, Falk, Stephen, Izbicki, Jakob R., Middleton, Gary William, Cummins, Sebastian, Ross, Paul J., Wasan, Harpreet, McDonald, Alec, Crosby, Tom, Ting, Yuk, Patel, Kinnari, Sherriff, David, Soomal, Rubin, Borg, David, Sothi, Sharmila, Hammel, Pascal, Lerch, Markus M., Mayerle, Julia, Tjaden, Christine, Strobel, Oliver, Hackert, Thilo, Buchler, Markus W., Neoptolemos, John P., Hill, Mark, Corrie, Pippa, Hickish, Tamas, Napier, Mark, Slater, Sarah, Valle, Juan, Shablak, Alaaeldin, Cunnell, Michelle, Guimbaud, Rosine, Roques, Tom, Iveson, Tim, Jamil, Arshad, Robinson, Angus, Garcia-Alonso, Angel, Chang, David, Tsang, David, Wadd, Nick, Wall, Lucy, Nielsen, Niels Hilmer, Lerch, Markus, Mehta, Ajay, Sivaramalingam, Muthiah, Fyfe, David, Osborne, Richard, Blesing, Claire, Bulusu, Venkata Ramesh, Rathbone, Emma, Seitz, Jean-Francois, Beaumont, Erica, Dernedde, Ulrike, McAdam, Karen, Dimopoulos, Prokopios, Cominos, Mathilda, Askill, Colin, Piwowar, Andrzej, Bachet, Jean-Baptiste, Sumpter, Kate, Raouf, Sherif, Nicoll, Jonathan, Rees, Charlotte, Dhinakaran, Kathirvelu, Haux, Johan, Bengrine-Lefevre, Leila, Terrebonne, Eric, Shankland, Catherine, Palmer, Cheryl, Medley, Louise, Toy, Elizabeth, Kaur, Jasvinder, Gupta, Kamalnayan, Cheeseman, Sue, Patterson, Daniel, Candish, Charles, Thompson, Joyce, Coxon, Fareeda, Connolly, Caroline, McPhail, Neil, Williams, Rachel, Flygare, Petra, Elmlund, Mattias, Artru, Pascal, Millat, Bertrand, Jones, Robert P., Psarelli, Eftychia-Eirini, Jackson, Richard, Ghaneh, Paula, Halloran, Christopher M., Palmer, Daniel H., Campbell, Fiona, Valle, Juan W., Faluyi, Olusola, O'Reilly, Derek A., Cunningham, David, Wadsley, Jonathan, Darby, Suzanne, Meyer, Tim, Gillmore, Roopinder, Anthoney, Alan, Lind, Pehr, Glimelius, Bengt, Falk, Stephen, Izbicki, Jakob R., Middleton, Gary William, Cummins, Sebastian, Ross, Paul J., Wasan, Harpreet, McDonald, Alec, Crosby, Tom, Ting, Yuk, Patel, Kinnari, Sherriff, David, Soomal, Rubin, Borg, David, Sothi, Sharmila, Hammel, Pascal, Lerch, Markus M., Mayerle, Julia, Tjaden, Christine, Strobel, Oliver, Hackert, Thilo, Buchler, Markus W., Neoptolemos, John P., Hill, Mark, Corrie, Pippa, Hickish, Tamas, Napier, Mark, Slater, Sarah, Valle, Juan, Shablak, Alaaeldin, Cunnell, Michelle, Guimbaud, Rosine, Roques, Tom, Iveson, Tim, Jamil, Arshad, Robinson, Angus, Garcia-Alonso, Angel, Chang, David, Tsang, David, Wadd, Nick, Wall, Lucy, Nielsen, Niels Hilmer, Lerch, Markus, Mehta, Ajay, Sivaramalingam, Muthiah, Fyfe, David, Osborne, Richard, Blesing, Claire, Bulusu, Venkata Ramesh, Rathbone, Emma, Seitz, Jean-Francois, Beaumont, Erica, Dernedde, Ulrike, McAdam, Karen, Dimopoulos, Prokopios, Cominos, Mathilda, Askill, Colin, Piwowar, Andrzej, Bachet, Jean-Baptiste, Sumpter, Kate, Raouf, Sherif, Nicoll, Jonathan, Rees, Charlotte, Dhinakaran, Kathirvelu, Haux, Johan, Bengrine-Lefevre, Leila, Terrebonne, Eric, Shankland, Catherine, Palmer, Cheryl, Medley, Louise, Toy, Elizabeth, Kaur, Jasvinder, Gupta, Kamalnayan, Cheeseman, Sue, Patterson, Daniel, Candish, Charles, Thompson, Joyce, Coxon, Fareeda, Connolly, Caroline, McPhail, Neil, Williams, Rachel, Flygare, Petra, Elmlund, Mattias, Artru, Pascal, and Millat, Bertrand

Abstract

Importance: The patterns of disease recurrence after resection of pancreatic ductal adenocarcinoma with adjuvant chemotherapy remain unclear. Objective: To define patterns of recurrence after adjuvant chemotherapy and the association with survival. Design, Setting, and Participants: Prospectively collected data from the phase 3 European Study Group for Pancreatic Cancer 4 adjuvant clinical trial, an international multicenter study. The study included 730 patients who had resection and adjuvant chemotherapy for pancreatic cancer. Data were analyzed between July 2017 and May 2019. Interventions: Randomization to adjuvant gemcitabine or gemcitabine plus capecitabine. Main Outcomes and Measures: Overall survival, recurrence, and sites of recurrence. Results: Of the 730 patients, median age was 65 years (range 37-81 years), 414 were men (57%), and 316 were women (43%). The median follow-up time from randomization was 43.2 months (95% CI, 39.7-45.5 months), with overall survival from time of surgery of 27.9 months (95% CI, 24.8-29.9 months) with gemcitabine and 30.2 months (95% CI, 25.8-33.5 months) with the combination (HR, 0.81; 95% CI, 0.68-0.98; P=.03). The 5-year survival estimates were 17.1% (95% CI, 11.6%-23.5%) and 28.0% (22.0%-34.3%), respectively. Recurrence occurred in 479 patients (65.6%); another 78 patients (10.7%) died without recurrence. Local recurrence occurred at a median of 11.63 months (95% CI, 10.05-12.19 months), significantly different from those with distant recurrence with a median of 9.49 months (95% CI, 8.44-10.71 months) (HR, 1.21; 95% CI, 1.01-1.45; P=.04). Following recurrence, the median survival was 9.36 months (95% CI, 8.08-10.48 months) for local recurrence and 8.94 months (95% CI, 7.82-11.17 months) with distant recurrence (HR, 0.89; 95% CI, 0.73-1.09; P=.27). The median overall survival of patients with distant-only recurrence (23.03 months; 95% CI, 19.55-25.85 months) or local with distant recurrence (23.82 months; 95% CI, 17.48-28.32

Published
2019
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40. The Impact of Positive Resection Margins on Survival and Recurrence Following Resection and Adjuvant Chemotherapy for Pancreatic Ductal Adenocarcinoma

Author

Ghaneh, Paula, Kleeff, Jorg, Halloran, Christopher M., Raraty, Michael, Jackson, Richard, Melling, James, Jones, Owain, Palmer, Daniel H., Cox, Trevor F., Smith, Chloe J., O'Reilly, Derek A., Izbicki, Jakob R., Scarfe, Andrew G., Valle, Juan W., McDonald, Alexander C., Carter, Ross, Tebbutt, Niall C., Goldstein, David, Padbury, Robert, Shannon, Jennifer, Dervenis, Christos, Glimelius, Bengt, Deakin, Mark, Anthoney, Alan, Lerch, Markus M., Mayerle, Julia, Olah, Attila, Rawcliffe, Charlotte L., Campbell, Fiona, Strobel, Oliver, Buechler, Markus W., Neoptolemos, John P., Ghaneh, Paula, Kleeff, Jorg, Halloran, Christopher M., Raraty, Michael, Jackson, Richard, Melling, James, Jones, Owain, Palmer, Daniel H., Cox, Trevor F., Smith, Chloe J., O'Reilly, Derek A., Izbicki, Jakob R., Scarfe, Andrew G., Valle, Juan W., McDonald, Alexander C., Carter, Ross, Tebbutt, Niall C., Goldstein, David, Padbury, Robert, Shannon, Jennifer, Dervenis, Christos, Glimelius, Bengt, Deakin, Mark, Anthoney, Alan, Lerch, Markus M., Mayerle, Julia, Olah, Attila, Rawcliffe, Charlotte L., Campbell, Fiona, Strobel, Oliver, Buechler, Markus W., and Neoptolemos, John P.

Abstract

Objective and Background: Local and distant disease recurrence are frequently observed following pancreatic cancer resection, but an improved understanding of resection margin assessment is required to aid tailored therapies Methods: Analyses were carried out to assess the association between clinical characteristics and margin involvement as well as the effects of individual margin involvement on site of recurrence and overall and recurrence-free survival using individual patient data from the European Study Group for Pancreatic Cancer (ESPAC)-3 randomized controlled trial. Results: There were 1151 patients, of whom 505 (43.9%) had an RI resection. The median and 95% confidence interval (CI) overall survival was 24.9 (22.9-27.2) months for 646 (56.1%) patients with resection margin negative R0 >1 mm) tumors, 25.4 (21.6 30.4) months for 146 (12.7%) patients with RI <1 mm positive resection margins, and 18.7 (17.2-21.1) months for 359 (31.2%) patients with R1-direct positive margins (P < 0.001). In multivariable analysis, overall R 1-direct tumor margins, poor tumor differentiation, positive lymph node status, WHO performance status ≥ 1, maximum tumor size, and RI-direct posterior resection margin were all independently significantly associated with reduced overall and recurrence-free survival. Competing risks analysis showed that overall R1-direct positive resection margin status, positive lymph node status. WHO performance status 1, and R1-direct positive superior mesenteric/medial margin resection status were all significantly associated with local recurrence. Conclusions: RI-direct resections were associated with significantly reduced overall and recurrence-free survival following pancreatic cancer resection. Resection margin involvement was also associated with an increased risk for local recurrence.

Published
2019
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42. Postpancreatectomy Acute Pancreatitis (PPAP)

Author

Marchegiani, Giovanni, Barreto, Savio George, Bannone, Elisa, Sarr, Michael, Vollmer, Charles M., Connor, Saxon, Falconi, Massimo, Besselink, Marc G., Salvia, Roberto, Wolfgang, Christopher L., Zyromski, Nicholas J., Yeo, Charles J., Adham, Mustapha, Siriwardena, Ajith K., Takaori, Kyoichi, Hilal, Mohammad Abu, Loos, Martin, Probst, Pascal, Hackert, Thilo, Strobel, Oliver, Busch, Olivier R. C., Lillemoe, Keith D., Miao, Yi, Halloran, Christopher M., Werner, Jens, Friess, Helmut, Izbicki, Jakob R., Bockhorn, Maximillian, Vashist, Yogesh K., Conlon, Kevin, Passas, Ioannis, Gianotti, Luca, Del Chiaro, Marco, Schulick, Richard D., Montorsi, Marco, Oláh, Attila, Fusai, Giuseppe Kito, Serrablo, Alejandro, Zerbi, Alessandro, Fingerhut, Abe, Andersson, Roland, Padbury, Robert, Dervenis, Christos, Neoptolemos, John P., Bassi, Claudio, Büchler, Markus W., and Shrikhande, Shailesh V.

Published
2022
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44. The Impact of Positive Resection Margins on Survival and Recurrence Following Resection and Adjuvant Chemotherapy for Pancreatic Ductal Adenocarcinoma

Author

Ghaneh, Paula, primary, Kleeff, Jorg, additional, Halloran, Christopher M., additional, Raraty, Michael, additional, Jackson, Richard, additional, Melling, James, additional, Jones, Owain, additional, Palmer, Daniel H., additional, Cox, Trevor F., additional, Smith, Chloe J., additional, O’Reilly, Derek A., additional, Izbicki, Jakob R., additional, Scarfe, Andrew G., additional, Valle, Juan W., additional, McDonald, Alexander C., additional, Carter, Ross, additional, Tebbutt, Niall C., additional, Goldstein, David, additional, Padbury, Robert, additional, Shannon, Jennifer, additional, Dervenis, Christos, additional, Glimelius, Bengt, additional, Deakin, Mark, additional, Anthoney, Alan, additional, Lerch, Markus M., additional, Mayerle, Julia, additional, Oláh, Attila, additional, Rawcliffe, Charlotte L., additional, Campbell, Fiona, additional, Strobel, Oliver, additional, Büchler, Markus W., additional, and Neoptolemos, John P., additional

Published
2019
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45. SARS-CoV-2 infection in acute pancreatitis increases disease severity and 30-day mortality: COVID PAN collaborative study.

Author

Pandanaboyana, Sanjay, Moir, John, Leeds, John S., Oppong, Kofi, Kanwar, Aditya, Marzouk, Ahmed, Belgaumkar, Ajay, Gupta, Ajay, Siriwardena, Ajith K., Haque, Ali Raza, Awan, Altaf, Balakrishnan, Anita, Rawashdeh, Arab, Ivanov, Bogdan, Parmar, Chetan, Halloran, Christopher M., Caruana, Clifford, Borg, Cynthia-Michelle, Gomez, Dhanny, and Damaskos, Dimitrios

Subjects
CHRONIC pancreatitis, COVID-19, SARS-CoV-2, PANCREATITIS
Published
2021
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47. Comparison of adjuvant gemcitabine and capecitabine with gemcitabine monotherapy in patients with resected pancreatic cancer (ESPAC-4) : a multicentre, open-label, randomised, phase 3 trial

Author

Neoptolemos, John P., Palmer, Daniel H., Ghaneh, Paula, Psarelli, Eftychia E., Valle, Juan W., Halloran, Christopher M., Faluyi, Olusola, O'Reilly, Derek A., Cunningham, David, Wadsley, Jonathan, Darby, Suzanne, Meyer, Tim, Gillmore, Roopinder, Anthoney, Alan, Lind, Pehr, Glimelius, Bengt, Falk, Stephen, Izbicki, Jakob R., Middleton, Gary William, Cummins, Sebastian, Ross, Paul J., Wasan, Harpreet, McDonald, Alec, Crosby, Tom, Ma, Yuk Ting, Patel, Kinnari, Sherriff, David, Soomal, Rubin, Borg, David, Sothi, Sharmila, Hammel, Pascal, Hackert, Thilo, Jackson, Richard, Buechler, Markus W., Neoptolemos, John P., Palmer, Daniel H., Ghaneh, Paula, Psarelli, Eftychia E., Valle, Juan W., Halloran, Christopher M., Faluyi, Olusola, O'Reilly, Derek A., Cunningham, David, Wadsley, Jonathan, Darby, Suzanne, Meyer, Tim, Gillmore, Roopinder, Anthoney, Alan, Lind, Pehr, Glimelius, Bengt, Falk, Stephen, Izbicki, Jakob R., Middleton, Gary William, Cummins, Sebastian, Ross, Paul J., Wasan, Harpreet, McDonald, Alec, Crosby, Tom, Ma, Yuk Ting, Patel, Kinnari, Sherriff, David, Soomal, Rubin, Borg, David, Sothi, Sharmila, Hammel, Pascal, Hackert, Thilo, Jackson, Richard, and Buechler, Markus W.

Abstract

Background: The ESPAC-3 trial showed that adjuvant gemcitabine is the standard of care based on similar survival to and less toxicity than adjuvant 5-fluorouracil/folinic acid in patients with resected pancreatic cancer. Other clinical trials have shown better survival and tumour response with gemcitabine and capecitabine than with gemcitabine alone in advanced or metastatic pancreatic cancer. We aimed to determine the efficacy and safety of gemcitabine and capecitabine compared with gemcitabine monotherapy for resected pancreatic cancer. Methods: We did a phase 3, two-group, open-label, multicentre, randomised clinical trial at 92 hospitals in England, Scotland, Wales, Germany, France, and Sweden. Eligible patients were aged 18 years or older and had undergone complete macroscopic resection for ductal adenocarcinoma of the pancreas (R0 or R1 resection). We randomly assigned patients (1: 1) within 12 weeks of surgery to receive six cycles of either 1000 mg/m(2) gemcitabine alone administered once a week for three of every 4 weeks (one cycle) or with 1660 mg/m(2) oral capecitabine administered for 21 days followed by 7 days' rest (one cycle). Randomisation was based on a minimisation routine, and country was used as a stratification factor. The primary endpoint was overall survival, measured as the time from randomisation until death from any cause, and assessed in the intention-to-treat population. Toxicity was analysed in all patients who received trial treatment. This trial was registered with the EudraCT, number 2007-004299-38, and ISRCTN, number ISRCTN96397434. Findings: Of 732 patients enrolled, 730 were included in the final analysis. Of these, 366 were randomly assigned to receive gemcitabine and 364 to gemcitabine plus capecitabine. The Independent Data and Safety Monitoring Committee requested reporting of the results after there were 458 (95%) of a target of 480 deaths. The median overall survival for patients in the gemcitabine plus capecitabine group was

Published
2017
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48. Partial pancreatoduodenectomy versus duodenum-preserving pancreatic head resection in chronic pancreatitis: the multicentre, randomised, controlled, double-blind ChroPac trial

Author

Diener, Markus K, primary, Hüttner, Felix J, additional, Kieser, Meinhard, additional, Knebel, Phillip, additional, Dörr-Harim, Colette, additional, Distler, Marius, additional, Grützmann, Robert, additional, Wittel, Uwe A, additional, Schirren, Rebekka, additional, Hau, Hans-Michael, additional, Kleespies, Axel, additional, Heidecke, Claus-Dieter, additional, Tomazic, Ales, additional, Halloran, Christopher M, additional, Wilhelm, Torsten J, additional, Bahra, Marcus, additional, Beckurts, Tobias, additional, Börner, Thomas, additional, Glanemann, Matthias, additional, Steger, Ulrich, additional, Treitschke, Frank, additional, Staib, Ludger, additional, Thelen, Karsten, additional, Bruckner, Thomas, additional, Mihaljevic, André L, additional, Werner, Jens, additional, Ulrich, Alexis, additional, Hackert, Thilo, additional, Büchler, Markus W, additional, Rossion, Inga, additional, Kunz, Alexandra, additional, Hund, Evelin, additional, Limprecht, Ronald, additional, Schlitt, Hans Jürgen, additional, Mössner, Joachim, additional, Seiler, Christoph M, additional, Ihorst, Gabriele, additional, Di Sebastiano, Pierluigi, additional, Witzigmann, Helmut, additional, Klein, Fritz, additional, Berthold, Heike, additional, Körnlein, Heike, additional, Hopt, Ulrich, additional, Sick, Olivia, additional, Keck, Tobias, additional, Partecke, Lars Ivo, additional, Peters, Sebastian, additional, Lerch, Markus M, additional, Maichle, Barbara, additional, Erni, Birgit, additional, Bunjes-Schmieger, Sabine, additional, Igel, Sarah, additional, Stemmle, Svenja, additional, Neoptolemos, John P, additional, Raraty, Michael G T, additional, Petric, Miha, additional, Niedergethmann, Marco, additional, Schwarzmeier, Claudia, additional, Renz, Bernhard, additional, Schreib, Brigitte, additional, Thasler, Wolfgang E, additional, Schoenberg, Michael H, additional, Friess, Helmut, additional, Reim, Daniel, additional, Ceyhan, Güralp O, additional, Diehl-Bein, Monika, additional, Simon, Thomas, additional, Gehrig, Tobias, additional, Hoffer, Marion, additional, and Germer, Christoph Thomas, additional

Published
2017
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50. Outcomes From Minimal Access Retroperitoneal and Open Pancreatic Necrosectomy in 394 Patients With Necrotizing Pancreatitis

Author

Gomatos, Ilias P., primary, Halloran, Christopher M., additional, Ghaneh, Paula, additional, Raraty, Michael G.T., additional, Polydoros, Fotis, additional, Evans, Jonathan C., additional, Smart, Howard L., additional, Yagati-Satchidanand, R., additional, Garry, Jo M., additional, Whelan, Philip A., additional, Hughes, Faye E., additional, Sutton, Robert, additional, and Neoptolemos, John P., additional

Published
2016
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