10,026 results on '"Halling, A"'
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2. The Count of Abranhos by José Maria Eça de Queirós (review)
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Halling, Anna-Lisa
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- 2020
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3. 2016 International Siglo de Oro Drama Festival
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Halling, Anna-Lisa, Hegstrom, Valerie, Patterson, Charles, White, Jared S., and Cowling, Erin
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- 2017
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4. Luis Vélez de Guevara. La niña de Gómez Arias ed. by William R. Manson and C. George Peale (review)
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Halling, Anna-Lisa
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- 2017
5. 2015 International Siglo de Oro Drama Festival Coordinated by Anna-Lisa Halling
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Halling, Anna-Lisa
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- 2016
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6. Innovationen im Ostseeraum: Nils Alwall, Lembit Norviit, Adolfs Martins Steins und die künstliche Niere
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Hansson, Nils, Salaks, Juris, Moll, Friedrich H., Halling, Thorsten, and Tammiksaar, Erki
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- 2024
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7. Prevalence and incidence of personality disorders among children and adolescents in Danish mental health services: a nationwide register study
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Klinkby, Ida Maria Ingeholm, Hastrup, Lene Halling, Bo, Sune, Storebø, Ole Jakob, Simonsen, Erik, and Kongerslev, Mickey T.
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- 2024
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8. Diálogos en las tablas: Últimas tendencias de la puesta en escena del teatro clásico español ed. by María Bastianes et al. (review)
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Halling, Anna-Lisa
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- 2016
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9. 2013 Siglo de Oro Drama Festival, Chamizal
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Halling, Anna-Lisa and Vidler, Laura L.
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- 2015
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10. RNA Sequencing for Solid Tumor Fusion Gene Detection: Proficiency Testing Practice and Performance Comparison
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Bridge, Julia A., Halling, Kevin C., Moncur, Joel T., Souers, Rhona J., Hameed, Meera R., Fernandes, Helen, Roy, Angshumoy, Surrey, Lea, Tafe, Laura J., Vasalos, Patricia, and Lopez-Terrada, Dolores H.
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Tumors ,RNA sequencing ,Genes ,RNA ,Medical laboratories ,Health ,College of American Pathologists - Abstract
* Context.--Next-generation sequencing-based approaches using RNA have increasingly been used by clinical laboratories for the detection of fusion genes, intragenic rearrangements, and exon-skipping events. Correspondingly, the College of American Pathologists (CAP) has advanced RNA sequencing proficiency testing (PT) to ensure optimal performance of these assays. Objective.--To report on laboratory performance and practices of RNA sequencing for the detection of fusion genes, intragenic rearrangements, and exon-skipping events using CAP PT data from 8 mailings (2018-A through 2021-B). Design.--CAP PT RNA sequencing program results from 153 laboratories across 24 proficiency test specimens, interrogating 22 distinct engineered fusion transcripts, were analyzed for correct identification of the fusion event, associated performance variables, and laboratory practices. Results.--Overall, the 4-year program detection rate (sensitivity) was 95.5% (1486 of 1556 results). False-negative rates were 3.6% (53 of 1463) and 18.3% (17 of 93) for fusion gene and intragenic rearrangement/exon-skipping events, respectively. Only 19 false-positive results were reported among the 8 PT mailings, and most were likely the result of preanalytical or postanalytical errors. There were no practice characteristics (eg, instrumentation, sequencing method) significantly associated with the fusion detection results. Conclusions.--These data reveal a high overall sensitivity and specificity for fusion gene detection by participating laboratories using clinical RNA sequencing. Performance was comparable across all laboratories, regardless of methodology. The fraction of false-negative results for intragenic rearrangement/exon-skipping events was greater than that for the chimeric fusion genes. False-negative results could not be attributed to any specific practice characteristics., Fusion oncogenes represent valuable biomarkers that aid in diagnostic classification and prognostication, as well as serving as therapeutic targets. (1-4) Examples of structural alterations/mutations that may lead to chimeric fusions [...]
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- 2024
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11. The mitochondrial mRNA-stabilizing protein SLIRP regulates skeletal muscle mitochondrial structure and respiration by exercise-recoverable mechanisms
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Pham, Tang Cam Phung, Raun, Steffen Henning, Havula, Essi, Henriquez-Olguín, Carlos, Rubalcava-Gracia, Diana, Frank, Emma, Fritzen, Andreas Mæchel, Jannig, Paulo R., Andersen, Nicoline Resen, Kruse, Rikke, Ali, Mona Sadek, Irazoki, Andrea, Halling, Jens Frey, Ringholm, Stine, Needham, Elise J., Hansen, Solvejg, Lemminger, Anders Krogh, Schjerling, Peter, Petersen, Maria Houborg, de Almeida, Martin Eisemann, Jensen, Thomas Elbenhardt, Kiens, Bente, Hostrup, Morten, Larsen, Steen, Ørtenblad, Niels, Højlund, Kurt, Kjær, Michael, Ruas, Jorge L., Trifunovic, Aleksandra, Wojtaszewski, Jørgen Frank Pind, Nielsen, Joachim, Qvortrup, Klaus, Pilegaard, Henriette, Richter, Erik Arne, and Sylow, Lykke
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- 2024
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12. Optimising the diagnostic accuracy of First post-contrAst SubtracTed breast MRI (FAST MRI) through interpretation-training: a multicentre e-learning study, mapping the learning curve of NHS Breast Screening Programme (NHSBSP) mammogram readers using an enriched dataset
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Jones, Lyn I., Marshall, Andrea, Geach, Rebecca, Elangovan, Premkumar, O’Flynn, Elizabeth, Timlin, Tony, McKeown-Keegan, Sadie, Rose, Janice, Vinnicombe, Sarah, Taylor-Phillips, Sian, Halling-Brown, Mark, and Dunn, Janet A.
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- 2024
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13. Schema therapy versus treatment as usual for outpatients with difficult-to-treat depression: study protocol for a parallel group randomized clinical trial (DEPRE-ST)
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Arendt, Ida-Marie T. P., Gondan, Matthias, Juul, Sophie, Hastrup, Lene Halling, Hjorthøj, Carsten, Bach, Bo, Videbech, Poul, Jørgensen, Martin Balslev, and Moeller, Stine Bjerrum
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- 2024
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14. Factors influencing hospitalization or emergency department visits and mortality in type 2 diabetes following the onset of new cardiovascular diagnoses in a population-based study
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Agvall, Björn, Jonasson, Junmei Miao, Galozy, Alexander, and Halling, Anders
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- 2024
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15. Der Einfluss von Arzneimitteln auf die Mundschleimhaut
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Halling, Frank and Reichert, Torsten E.
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- 2024
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16. Oral History in der Medizin – Herausforderungen und Chancen
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Söhner, Felicitas, Hansson, Nils, and Halling, Thorsten
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- 2024
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17. Exploring the Impact of Age and Pre-Stroke Modified Rankin Scale in Elderly Thrombectomy: A 15-Year Single-Center Experience
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Brian Anthony B. Enriquez, Heidi Kristine Halling, Christian Georg Lund, Bjørn Tennøe, Cathrine Brunborg, Mona Elisabeth Skjelland, Anne Hege Aamodt, and Karolina Skagen
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acute stroke therapy ,thrombectomy ,aging ,pre-stroke mrs ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
Introduction: The selection of endovascular thrombectomy (EVT) for acute ischemic stroke in the elderly remains challenging due to the underrepresentation of these patients in landmark randomized trials. The aim of this study was to assess the association between age and the pre-stroke modified Rankin scale score with functional outcomes after EVT in elderly patients aged ≥80 years. Methods: We prospectively collected data from consecutive elderly patients who underwent EVT of the anterior or posterior circulation at our institution between 2007 and 2022. Clinical and radiological parameters were analyzed using a fair outcome (mRS ≤3 or retained pre-stroke mRS score of 4) as the primary outcome. Results: In total, 307 elderly patients were included in the analysis. Fair functional outcomes were achieved in 162 (53%) patients. Eighty-four (27.4%) patients were deceased at 3-month follow-up and the mortality rate increased to 37.1% (114 deceased) at 1-year follow-up. The likelihood of achieving a fair functional outcome decreased by 8% for every 1-year age increase (OR 0.81, 95% CI 0.73–0.90). Lower National Institutes of Health Stroke Scale (OR 0.89, 95% CI 0.85–0.93, p < 0.001) and pre-stroke mRS (OR 0.67, 95% CI 0.53–0.84, p < 0.001) were associated with fair outcomes. Conclusions: EVT in elderly patients with stroke is beneficial in selected cases. Increasing age was associated with an increased risk of an mRS change to 4 or worse and death within 1 year. The pre-stroke mRS may aid clinicians in the selection of elderly patients for EVT.
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- 2024
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18. Factors associated with development of retinopathy in patients with type 2 diabetes mellitus at onset and within three years after diagnosis
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Kajsa Andersson, Anders Halling, and Björn Agvall
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Diabetes mellitus complication ,Type 2 diabetes ,diabetic retinopathy ,Public aspects of medicine ,RA1-1270 - Abstract
Objective To investigate the prevalence of diabetes retinopathy and evaluate the factors influencing its occurrence both at the onset of type 2 diabetes (T2D) and three years into its duration.Design Retrospective population-based study.Setting Data was retrieved from Regional Healthcare Information Platform in Region Halland 2016–2020.Subjects Patients 35-75 years old in Region Halland receiving first-time diabetes diagnosis according to ICD-code E11-14 in 2016–17. The total cohort consisted of 1659 patients.Main outcome measures The main outcome measure of the study was the occurrence of diabetes retinopathy at onset and within three years from the diabetes diagnosis. Multivariate logistic regression analysis was conducted for diabetes retinopathy at onset and within three years, adjusted for age, gender, comorbidities, levels of HbA1c, cholesterol, kidney functional and blood pressure.Results At onset, there were 12% with diabetes retinopathy and after three years, 32% of the patients had developed diabetes retinopathy. In the study cohort, 71 of patients who were examined with fundus photography within three years after onset, and 8% had had dietary recommendation without pharmacotherapy. High HbA1c levels, blood pressure values and impaired renal function already at onset were associated with development of diabetes retinopathy at onset and this association persisted after three years. The odds ratio for diabetes retinopathy was increased adjusted for HbA1c elevations, renal impairment, and increased blood pressure at index and when adjusted for these variables three years from index.Conclusion These findings indicate that the risk of developing diabetes retinopathy is present early on at onset and within the first three years of diabetes diagnosis. This highlights the importance of promptly regulating glucose- and blood-pressure levels and follow up kidney dysfunction to mitigate the risk of diabetes retinopathy.
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- 2024
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19. Contact X-ray Brachytherapy as a sole treatment in selected patients with early rectal cancer – Multi-centre study
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Ngu Wah Than, D. Mark Pritchard, David M. Hughes, Kai Shing Yu, Helen S. Minnaar, Amandeep Dhadda, Jamie Mills, Joakim Folkesson, Calin Radu, C.A. Duckworth, Helen Wong, Muneeb Ul Haq, Rajaram Sripadam, Mark D. Halling-Brown, Alexandra J. Stewart, and Arthur Sun Myint
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Rectal cancer ,Contact X-ray Brachytherapy ,Papillon ,Organ preservation ,Sole treatment ,Medical physics. Medical radiology. Nuclear medicine ,R895-920 ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
Background and purpose: Radical surgery is the standard of care for early rectal cancer. However, alternative organ-preserving approaches are attractive, especially in frail or elderly patients as these avoid surgical complications. We have assessed the efficacy of sole Contact X-ray Brachytherapy (CXB) treatment in stage-1 rectal cancer patients who were unsuitable for or declined surgery. Materials and methods: This retrospective multi-centre study (2009–2021) evaluated 76 patients with T1/2-N0-M0 rectal adenocarcinomas who were treated with CXB alone. Outcomes were assessed for the entire cohort and sub-groups based on the T-stage and the criteria for receiving CXB alone; Group A: patients who were fit enough for surgery but declined, Group B: patients who were high-risk for surgery and Group C: patients who had received prior pelvic radiation for a different cancer. Results: With a median follow-up of 26(IQR:12–49) months, initial clinical Complete Response (cCR) was 82(70–93)% with rates of local regrowth 18(8–29)%, 3-year actuarial local control (LC) 84(75–95)%, distant relapse 3 %, and no nodal relapse. 5-year disease-free survival (DFS) and overall survival (OS) were 66(48–78)% and 58(44–75)%. Lower OS was observed in Groups B [HR:2.54(95 %CI:1.17, 5.59), p = 0.02] and C [HR:2.75(95 %CI:1.15, 6.58), p = 0.03]. Previous pelvic radiation predicted lower cCR and OS. The main toxicity was G1-2 rectal bleeding (26 %) and symptoms of impaired anal sphincter function were not reported in any patients. Conclusion: CXB treatment alone achieved a high cCR rate with satisfactory LC and DFS. Inferior oncological outcomes were observed in patients who had received prior pelvic radiotherapy. CXB alone, with its favourable toxicity profile and avoidance of general anaesthesia and surgery risks, therefore, can be considered for patients who are unsuitable for or refuse surgery.
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- 2024
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20. Peer review of the pesticide risk assessment of the active substance penoxsulam
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European Food Safety Authority (EFSA), Fernando Álvarez, Maria Arena, Domenica Auteri, Sofia Batista Leite, Marco Binaglia, Anna Federica Castoldi, Arianna Chiusolo, Ana‐Andreea Cioca, Angelo Colagiorgi, Mathilde Colas, Federica Crivellente, Chloe De Lentdecker, Isabella De Magistris, Mark Egsmose, Gabriella Fait, Franco Ferilli, German Giner Santonja, Varvara Gouliarmou, Katrin Halling, Laia Herrero Nogareda, Alessio Ippolito, Frederique Istace, Samira Jarrah, Dimitra Kardassi, Aude Kienzler, Anna Lanzoni, Roberto Lava, Renata Leuschner, Alberto Linguadoca, Jochem Louisse, Christopher Lythgo, Oriol Magrans, Iris Mangas, Galini Mavriou, Andrea Mioč, Ileana Miron, Tunde Molnar, Laura Padovani, Vincenzo Padricello, Martina Panzarea, Juan Manuel Parra Morte, Simone Rizzuto, Anamarija Romac, Agnès Rortais, Miguel Santos, Rositsa Serafimova, Rachel Sharp, Csaba Szentes, Andrea Terron, Anne Theobald, Manuela Tiramani, Giorgia Vianello, and Laura Villamar‐Bouza
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herbicide ,peer review ,penoxsulam ,pesticide ,risk assessment ,Nutrition. Foods and food supply ,TX341-641 ,Chemical technology ,TP1-1185 - Abstract
Abstract The conclusions of the European Food Safety Authority (EFSA) following the peer review of the initial risk assessments carried out by the competent authorities of the rapporteur Member State, Italy, and co‐rapporteur Member State, Poland, for the pesticide active substance penoxsulam are reported. The context of the peer review was that required by Commission Implementing Regulation (EU) No 844/2012, as amended by Commission Implementing Regulation (EU) No 2018/1659. The conclusions were reached on the basis of the evaluation of the representative uses of penoxsulam as a herbicide on rice and chicory. The reliable end points, appropriate for use in regulatory risk assessment, are presented. Missing information identified as being required by the regulatory framework is listed. Concerns are reported where identified.
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- 2024
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21. Peer review of the pesticide risk assessment of the active substance elemental iron
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European Food Safety Authority (EFSA), Fernando Álvarez, Maria Arena, Domenica Auteri, Sofia Batista Leite, Marco Binaglia, Anna Federica Castoldi, Arianna Chiusolo, Angelo Colagiorgi, Mathilde Colas, Federica Crivellente, Chloe De Lentdecker, Isabella De Magistris, Mark Egsmose, Gabriella Fait, Franco Ferilli, German Giner Santonja, Varvara Gouliarmou, Katrin Halling, Laia Herrero Nogareda, Alessio Ippolito, Frederique Istace, Samira Jarrah, Dimitra Kardassi, Aude Kienzler, Anna Lanzoni, Roberto Lava, Renata Leuschner, Alberto Linguadoca, Jochem Louisse, Christopher Lythgo, Oriol Magrans, Iris Mangas, Andrea Mioč, Ileana Miron, Tunde Molnar, Laura Padovani, Vincenzo Padricello, Martina Panzarea, Juan Manuel Parra Morte, Simone Rizzuto, Anamarija Romac, Agnès Rortais, Miguel Santos, Rositsa Serafimova, Rachel Sharp, Csaba Szentes, Andrea Terron, Anne Theobald, Manuela Tiramani, Giorgia Vianello, and Laura Villamar‐Bouza
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elemental iron ,molluscicide ,peer review ,pesticide ,risk assessment ,Nutrition. Foods and food supply ,TX341-641 ,Chemical technology ,TP1-1185 - Abstract
Abstract The conclusions of the European Food Safety Authority (EFSA) following the peer review of the initial risk assessments carried out by the competent authority of the rapporteur Member State Austria for the pesticide active substance elemental iron and the considerations as regards the inclusion of the substance in Annex IV of Regulation (EC) No 396/2005 are reported. The context of the peer review was that required by Regulation (EC) No 1107/2009 of the European Parliament and of the Council. The conclusions were reached on the basis of the evaluation of the representative uses of elemental iron in field and greenhouses (permanent and non‐permanent structures) via granule application by spreading on all edible and non‐edible crops, ornamental plants and amenity grassland to control molluscs. The reliable endpoints, appropriate for use in regulatory risk assessment, are presented. Missing information identified as being required by the regulatory framework is listed.
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- 2024
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22. Peer review of the pesticide risk assessment of the active substance bixlozone
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European Food Safety Authority (EFSA), Fernando Álvarez, Maria Arena, Domenica Auteri, Sofia Batista Leite, Marco Binaglia, Anna Federica Castoldi, Arianna Chiusolo, Angelo Colagiorgi, Mathilde Colas, Federica Crivellente, Chloe De Lentdecker, Isabella De Magistris, Mark Egsmose, Gabriella Fait, Franco Ferilli, German Giner Santonja, Varvara Gouliarmou, Katrin Halling, Laia Herrero Nogareda, Alessio Ippolito, Frederique Istace, Samira Jarrah, Dimitra Kardassi, Aude Kienzler, Anna Lanzoni, Roberto Lava, Renata Leuschner, Alberto Linguadoca, Jochem Louisse, Christopher Lythgo, Oriol Magrans, Iris Mangas, Andrea Mioč, Ileana Miron, Tunde Molnar, Laura Padovani, Vincenzo Padricello, Martina Panzarea, Juan Manuel Parra Morte, Simone Rizzuto, Anamarija Romac, Agnès Rortais, Miguel Santos, Rositsa Serafimova, Rachel Sharp, Csaba Szentes, Andrea Terron, Anne Theobald, Manuela Tiramani, Giorgia Vianello, and Laura Villamar‐Bouza
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Bixlozone ,herbicide ,peer review ,pesticide ,risk assessment ,Nutrition. Foods and food supply ,TX341-641 ,Chemical technology ,TP1-1185 - Abstract
Abstract The conclusions of the European Food Safety Authority (EFSA) following the peer review of the initial risk assessments carried out by the competent authority of the rapporteur Member State, The Netherlands for the pesticide active substance bixlozone are reported. The context of the peer review was that required by Regulation (EC) No 1107/2009 of the European Parliament and of the Council. The conclusions were reached on the basis of the evaluation of the representative uses of bixlozone as an herbicide on winter cereals (wheat and barley), winter oilseed rape and maize via soil broadcast spray application in field. The reliable endpoints, appropriate for use in regulatory risk assessment are presented. Missing information identified as being required by the regulatory framework is listed. Concerns are identified.
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- 2024
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23. Peer review of the pesticide risk assessment of the active substance amidosulfuron
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European Food Safety Authority (EFSA), Fernando Álvarez, Maria Arena, Domenica Auteri, Sofia Batista Leite, Marco Binaglia, Anna Federica Castoldi, Arianna Chiusolo, Angelo Colagiorgi, Mathilde Colas, Federica Crivellente, Chloe De Lentdecker, Isabella De Magistris, Mark Egsmose, Gabriella Fait, Franco Ferilli, German Giner Santonja, Varvara Gouliarmou, Katrin Halling, Laia Herrero Nogareda, Alessio Ippolito, Frederique Istace, Samira Jarrah, Dimitra Kardassi, Aude Kienzler, Anna Lanzoni, Roberto Lava, Renata Leuschner, Alberto Linguadoca, Jochem Louisse, Christopher Lythgo, Oriol Magrans, Iris Mangas, Galini Mavriou, Andrea Mioč, Ileana Miron, Tunde Molnar, Laura Padovani, Vincenzo Padricello, Martina Panzarea, Juan Manuel Parra Morte, Simone Rizzuto, Anamarija Romac, Agnès Rortais, Miguel Santos, Rositsa Serafimova, Rachel Sharp, Csaba Szentes, Andrea Terron, Anne Theobald, Manuela Tiramani, Giorgia Vianello, and Laura Villamar‐Bouza
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amidosulfuron ,Article 12 confirmatory data ,herbicide ,peer review ,pesticide ,risk assessment ,Nutrition. Foods and food supply ,TX341-641 ,Chemical technology ,TP1-1185 - Abstract
Abstract The conclusions of the European Food Safety Authority (EFSA) following the peer review of the initial risk assessments carried out by the competent authorities of the rapporteur Member State, Finland, and co‐rapporteur Member State, Croatia, for the pesticide active substance amidosulfuron and the assessment of confirmatory data following the Article 12 MRL review are reported. The context of the peer review was that required by Commission Implementing Regulation (EU) No 844/2012, as amended by Commission Implementing Regulation (EU) No 2018/1659. The conclusions were reached on the basis of the evaluation of the representative uses of amidosulfuron as a post‐emergence herbicide on winter cereals, spring cereals, flax and grass/pasture (all field uses). The reliable end points, appropriate for use in regulatory risk assessment are presented. Missing information identified as being required by the regulatory framework is listed. Concerns are reported where identified.
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- 2024
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24. Peer review of the pesticide risk assessment of the active substance flufenacet
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European Food Safety Authority (EFSA), Fernando Álvarez, Maria Arena, Domenica Auteri, Sofia Batista Leite, Marco Binaglia, Anna Federica Castoldi, Arianna Chiusolo, Angelo Colagiorgi, Mathilde Colas, Federica Crivellente, Chloe De Lentdecker, Isabella De Magistris, Mark Egsmose, Gabriella Fait, Franco Ferilli, German Giner Santonja, Varvara Gouliarmou, Katrin Halling, Laia Herrero Nogareda, Alessio Ippolito, Frederique Istace, Samira Jarrah, Dimitra Kardassi, Aude Kienzler, Anna Lanzoni, Roberto Lava, Renata Leuschner, Alberto Linguadoca, Jochem Louisse, Christopher Lythgo, Oriol Magrans, Iris Mangas, Galini Mavriou, Andrea Mioč, Ileana Miron, Tunde Molnar, Laura Padovani, Vincenzo Padricello, Martina Panzarea, Juan Manuel Parra Morte, Simone Rizzuto, Anamarija Romac, Agnès Rortais, Miguel Santos, Rositsa Serafimova, Rachel Sharp, Csaba Szentes, Andrea Terron, Anne Theobald, Manuela Tiramani, Giorgia Vianello, and Laura Villamar‐Bouza
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Art 12 confirmatory data ,flufenacet ,herbicide ,peer review ,pesticide ,risk assessment ,Nutrition. Foods and food supply ,TX341-641 ,Chemical technology ,TP1-1185 - Abstract
Abstract The conclusions of the European Food Safety Authority (EFSA) following the peer review of the initial risk assessments carried out by the competent authorities of the rapporteur Member State Poland and co‐rapporteur Member State France for the pesticide active substance flufenacet are reported. In addition, the assessment of the confirmatory data following the Article 12 maximum residue limit (MRL) review of Regulation (EC) No 396/2005 is also reported. The context of the peer review was that required by Commission Implementing Regulation (EU) No 844/2012. The conclusions were reached on the basis of the evaluation of the representative use of flufenacet as a herbicide on winter cereals. Confirmatory data following the Article 12 MRL review were assessed. The reliable end points, appropriate for use in regulatory risk assessment and the assessment of confirmatory data following the Article 12 MRL review, are presented. Missing information identified as being required by the regulatory framework is listed. Concerns are reported where identified.
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- 2024
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25. Forum: Oral History in der Medizin. Etwas Besonderes?
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Söhner, Felicitas, Arp, Agnès, Halling, Thorsten, Hansson, Nils, Hinz, Uta, Löffelbein, Nils, Schliwa, Constanze, and Sparing, Frank
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- 2024
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26. A Model Toward Formalizing and Monitoring Compliance of Investment Funds Activities.
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Nicolas Sannier, Marcello Ceci, Sallam Abualhaija, Domenico Bianculli, and Michael Halling
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- 2024
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27. Con quien vengo, vengo by Pedro Calderón de la Barca
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Halling, Anna-Lisa
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- 2011
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28. Preise in der Pathologie – eine Männerdomäne?
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Malik, Elisa, Halling, Thorsten, Dreher, Annegret, Marazia, Chantal, Esposito, Irene, Loerbroks, Adrian, and Hansson, Nils
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- 2024
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29. Optimising the diagnostic accuracy of First post-contrAst SubtracTed breast MRI (FAST MRI) through interpretation-training: a multicentre e-learning study, mapping the learning curve of NHS Breast Screening Programme (NHSBSP) mammogram readers using an enriched dataset
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Lyn I. Jones, Andrea Marshall, Rebecca Geach, Premkumar Elangovan, Elizabeth O’Flynn, Tony Timlin, Sadie McKeown-Keegan, Janice Rose, Sarah Vinnicombe, Sian Taylor-Phillips, Mark Halling-Brown, Janet A. Dunn, and the FAST MRI Study Group
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FAST MRI ,Abbreviated breast MRI ,Breast cancer ,Screening ,Formative assessment ,Medical education ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
Abstract Background Abbreviated breast MRI (FAST MRI) is being introduced into clinical practice to screen women with mammographically dense breasts or with a personal history of breast cancer. This study aimed to optimise diagnostic accuracy through the adaptation of interpretation-training. Methods A FAST MRI interpretation-training programme (short presentations and guided hands-on workstation teaching) was adapted to provide additional training during the assessment task (interpretation of an enriched dataset of 125 FAST MRI scans) by giving readers feedback about the true outcome of each scan immediately after each scan was interpreted (formative assessment). Reader interaction with the FAST MRI scans used developed software (RiViewer) that recorded reader opinions and reading times for each scan. The training programme was additionally adapted for remote e-learning delivery. Study design Prospective, blinded interpretation of an enriched dataset by multiple readers. Results 43 mammogram readers completed the training, 22 who interpreted breast MRI in their clinical role (Group 1) and 21 who did not (Group 2). Overall sensitivity was 83% (95%CI 81–84%; 1994/2408), specificity 94% (95%CI 93–94%; 7806/8338), readers’ agreement with the true outcome kappa = 0.75 (95%CI 0.74–0.77) and diagnostic odds ratio = 70.67 (95%CI 61.59–81.09). Group 1 readers showed similar sensitivity (84%) to Group 2 (82% p = 0.14), but slightly higher specificity (94% v. 93%, p = 0.001). Concordance with the ground truth increased significantly with the number of FAST MRI scans read through the formative assessment task (p = 0.002) but by differing amounts depending on whether or not a reader had previously attended FAST MRI training (interaction p = 0.02). Concordance with the ground truth was significantly associated with reading batch size (p = 0.02), tending to worsen when more than 50 scans were read per batch. Group 1 took a median of 56 seconds (range 8–47,466) to interpret each FAST MRI scan compared with 78 (14–22,830, p
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- 2024
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30. Schema therapy versus treatment as usual for outpatients with difficult-to-treat depression: study protocol for a parallel group randomized clinical trial (DEPRE-ST)
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Ida-Marie T. P. Arendt, Matthias Gondan, Sophie Juul, Lene Halling Hastrup, Carsten Hjorthøj, Bo Bach, Poul Videbech, Martin Balslev Jørgensen, and Stine Bjerrum Moeller
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Schema therapy ,Difficult-to-treat depression ,Treatment-resistant depression ,Treatment refractory depression ,Chronic depression ,Depressive personality disorder ,Medicine (General) ,R5-920 - Abstract
Abstract Background About one third of patients with depression are in a condition that can be termed as “difficult-to-treat”. Some evidence suggests that difficult-to-treat depression is associated with a higher frequency of childhood trauma and comorbid personality disorders or accentuated features. However, the condition is understudied, and the effects of psychotherapy for difficult-to-treat depression are currently uncertain. The aim of this trial is to investigate the beneficial and harmful effects of 30 sessions of individual schema therapy versus treatment as usual for difficult-to-treat depression in the Danish secondary, public mental health sector. Methods In this randomized, multi-centre, parallel-group, superiority clinical trial, 129 outpatients with difficult-to-treat depression will be randomized (1:1) to 30 sessions of individual schema therapy or treatment as usual; in this context mainly group-based, short-term cognitive behaviour or psychodynamic therapy. The primary outcome is the change from baseline in depressive symptoms 12 months after randomization, measured on the observer-rated 6-item Hamilton Rating Scale for Depression. The secondary outcomes are health-related quality of life assessed with the European Quality of Life 5 Dimensions 5 Level Version, functional impairment assessed with the Work and Social Adjustment Scale, psychological wellbeing assessed with the WHO-5 Well-being Index, and negative effects of treatment assessed with the Negative Effects Questionnaire. Exploratory outcomes are improvement on patient self-defined outcomes, personal recovery, anxiety symptoms, anger reactions, metacognitive beliefs about anger, and perseverative negative thinking. Outcomes will be assessed at 6, 12, and 24 months after randomization; the 12-month time-point being the primary time-point of interest. Outcome assessors performing the depression-rating, data managers, statisticians, the data safety and monitoring committee, and conclusion makers for the outcome article will be blinded to treatment allocation and results. To assess cost-effectiveness of the intervention, a health economic analysis will be performed. Discussion This trial will provide evidence on the beneficial and harmful effects, as well as the cost-effectiveness of schema therapy versus treatment as usual for outpatients with difficult-to-treat depression. The results can potentially improve treatment for a large and understudied patient group. Trial registration ClinicalTrials.gov NCT05833087. Registered on 15th April 2023 (approved without prompts for revision on 27th April 2023).
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- 2024
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31. Factors influencing hospitalization or emergency department visits and mortality in type 2 diabetes following the onset of new cardiovascular diagnoses in a population-based study
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Björn Agvall, Junmei Miao Jonasson, Alexander Galozy, and Anders Halling
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Type 2 diabetes ,Cardiovascular disease ,Healthcare utilization ,Mortality ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
Abstract Background Individuals with type 2 diabetes (T2D) are at increased risk of developing cardiovascular disease (CVD) which necessitates monitoring of risk factors and appropriate pharmacotherapy. This study aimed to identify factors predicting emergency department visits, hospitalizations, and mortality among T2D patients after being newly diagnosed with CVD. Methods In a retrospective observational study conducted in Region Halland, individuals aged > 40 years with T2D diagnosed between 2011 and 2019, and a new diagnosis of CVD between 2016 and 2019, were followed for one year from the date of CVD diagnosis. The first encounter for CVD diagnosis was categorized as inpatient-, outpatient-, primary-, or emergency department care. Follow-up included laboratory tests, blood pressure, pharmacotherapies, and healthcare utilization. Hazard ratios (HR) in two Cox regression analyses determined relative risks for emergency visits/hospitalization and mortality, adjusting for age, sex, glucose regulation, lipid levels, kidney function, blood pressure, pharmacotherapy, and healthcare utilization. Results The study included a total of 1759 T2D individuals who received a new CVD diagnosis, with 67% diagnosed during inpatient care. The average hospitalization stay was 6.5 days, and primary care follow-up averaged 10.1 visits. Patients with CVD diagnosed in primary care had a HR 0.52 (confidence interval [CI] 0.35–0.77) for emergency department visits/hospitalization, but age had a HR 1.02 (CI 1.00-1.03). Pharmacotherapy with insulin, DPP4-inhibitors, aldosterone antagonists, and beta-blockers had a raised HR. Highest mortality risk was observed when CVD was diagnosed inpatient care, systolic blood pressure 2,5 h 1.46 (CI 1.01–2.11) and associated with increased mortality risk. Pharmacotherapy with metformin had a HR 0.41 (CI 0.28–0.62), statins a HR 0.39 (CI 0.27–0.57), and a primary care follow-up
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- 2024
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32. 'Being ill was the easy part': exploring cancer survivors’ reactions to perceived challenges in engaging with primary healthcare
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Lars Garpenhag, Anders Halling, Susanna Calling, Linn Rosell, and Anna-Maria Larsson
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primary healthcare ,cancer survivors ,health services accessibility ,sweden ,qualitative research ,Medicine (General) ,R5-920 - Abstract
Purpose Cancer survivors experience barriers to primary healthcare (PHC) services. The aim was to explore reactions to and opinions about perceived challenges associated with PHC access and quality among cancer survivors in Sweden, including how they have acted to adapt to challenges. Methods Five semi-structured focus group interviews were conducted with cancer survivors (n = 20) from Skåne, Sweden, diagnosed with breast, prostate, lung, or colorectal cancer or malignant melanoma. Focus groups were mixed in regard to diagnosis. Data were analysed using a descriptive template analysis approach. Results In light of perceived challenges associated with access to adequate PHC, participants experienced that they had been forced to work hard to achieve functioning PHC contacts. The demands for self-sufficiency were associated with negative feelings such as loneliness and worry. Participants believed that cancer survivors who lack the ability to express themselves, or sufficient drive, risk missing out on necessary care due to the necessity of being an active patient. Conclusions The findings highlight negative patient experiences. They have implications for the organization of care for cancer survivors as they indicate a need for more efficient post-treatment coordination between cancer specialist care and PHC providers, as well as increased support for patients leaving primary cancer treatment.
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- 2024
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33. Rising incidence of severe maxillofacial space infections in Germany
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Meisgeier, Axel, Pienkohs, Simon, Dürrschnabel, Florian, Neff, Andreas, and Halling, Frank
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- 2024
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34. Peer review of the pesticide risk assessment of the active substance 1‐methylcyclopropene
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European Food Safety Authority (EFSA), Fernando Álvarez, Maria Arena, Domenica Auteri, Sofia Batista Leite, Marco Binaglia, Anna Federica Castoldi, Arianna Chiusolo, Angelo Colagiorgi, Mathilde Colas, Federica Crivellente, Chloe De Lentdecker, Isabella De Magistris, Mark Egsmose, Gabriella Fait, Franco Ferilli, German Giner Santonja, Varvara Gouliarmou, Katrin Halling, Laia Herrero Nogareda, Alessio Ippolito, Frederique Istace, Samira Jarrah, Dimitra Kardassi, Aude Kienzler, Anna Lanzoni, Roberto Lava, Renata Leuschner, Alberto Linguadoca, Jochem Louisse, Christopher Lythgo, Oriol Magrans, Iris Mangas, Galini Mavriou, Andrea Mioč, Ileana Miron, Tunde Molnar, Laura Padovani, Vincenzo Padricello, Martina Panzarea, Juan Manuel Parra Morte, Simone Rizzuto, Anamarija Romac, Agnès Rortais, Miguel Santos, Rositsa Serafimova, Rachel Sharp, Csaba Szentes, Andrea Terron, Anne Theobald, Manuela Tiramani, Giorgia Vianello, and Laura Villamar‐Bouza
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1‐methylcyclopropene ,peer review ,pesticide ,plant growth regulator ,risk assessment ,Nutrition. Foods and food supply ,TX341-641 ,Chemical technology ,TP1-1185 - Abstract
Abstract The conclusions of the European Food Safety Authority (EFSA) following the peer review of the initial risk assessments carried out by the competent authority of the rapporteur Member State The Netherlands for the pesticide active substance 1‐methylcyclopropene are reported. The context of the peer review was that required by Regulation (EC) No 1107/2009 of the European Parliament and of the Council for an amendment in approval conditions. The current approval of 1‐methylcyclopropene includes the specific provision ‘Only uses as plant growth regulator for post‐harvest storage in sealable warehouse may be authorised’. The applicant AgroFresh Holding France SAS submitted, in accordance with Article 7 of Reg. (EC) 1107/2009, an application to remove this specific provision in order to allow member states to authorise the use of products containing 1‐methylcyclopropene on outdoor crops pre‐harvest. The conclusions were reached on the basis of the evaluation of the representative use(s) of 1‐methylcyclopropene as a plant growth regulator via spray application on pome fruit. The reliable endpoints, appropriate for use in regulatory risk assessment are presented. Missing information identified as being required by the regulatory framework is listed. Concerns are reported where identified.
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- 2024
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35. Peer review of the pesticide risk assessment of the active substance triclopyr (variant triclopyr‐butotyl)
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European Food Safety Authority (EFSA), Fernando Álvarez, Maria Arena, Domenica Auteri, Sofia Batista Leite, Marco Binaglia, Anna Federica Castoldi, Arianna Chiusolo, Angelo Colagiorgi, Mathilde Colas, Federica Crivellente, Chloe De Lentdecker, Isabella De Magistris, Mark Egsmose, Gabriella Fait, Franco Ferilli, Varvara Gouliarmou, Katrin Halling, Laia Herrero Nogareda, Alessio Ippolito, Frederique Istace, Samira Jarrah, Dimitra Kardassi, Aude Kienzler, Anna Lanzoni, Roberto Lava, Renata Leuschner, Alberto Linguadoca, Jochem Louisse, Christopher Lythgo, Oriol Magrans, Iris Mangas, Ileana Miron, Tunde Molnar, Laura Padovani, Vincenzo Padricello, Martina Panzarea, Juan Manuel Parra Morte, Simone Rizzuto, Agnès Rortais, Rositsa Serafimova, Rachel Sharp, Csaba Szentes, Andrea Terron, Anne Theobald, Manuela Tiramani, Giorgia Vianello, and Laura Villamar‐Bouza
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herbicide ,MRL art 10 ,peer review ,pesticide ,risk assessment ,triclopyr ,Nutrition. Foods and food supply ,TX341-641 ,Chemical technology ,TP1-1185 - Abstract
Abstract The conclusions of the European Food Safety Authority (EFSA) following the peer review of the initial risk assessments carried out by the competent authorities of the rapporteur Member State Poland and co‐rapporteur Member State Hungary for the pesticide active substance triclopyr (variant triclopyr‐butotyl) and the assessment of applications for maximum residue levels (MRLs) are reported. The context of the peer review was that required by Commission Implementing Regulation (EU) No 844/2012, as amended by Commission Implementing Regulation (EU) No 2018/1659. The conclusions were reached on the basis of the evaluation of the representative uses of triclopyr (variant triclopyr‐butotyl) as a herbicide on established pasture and non‐recreational amenity grassland (field use). MRLs were assessed in rice. The reliable end points, appropriate for use in regulatory risk assessment and the proposed MRLs, are presented. Missing information identified as being required by the regulatory framework is listed. Concerns are reported where identified.
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- 2024
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36. Long-term impact of COVID-19 hospitalisation among individuals with pre-existing airway diseases in the UK: a multicentre, longitudinal cohort study – PHOSP-COVID
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Omer Elneima, John R. Hurst, Carlos Echevarria, Jennifer K. Quint, Samantha Walker, Salman Siddiqui, Petr Novotny, Paul E. Pfeffer, Jeremy S. Brown, Manu Shankar-Hari, Hamish J.C. McAuley, Olivia C. Leavy, Aarti Shikotra, Amisha Singapuri, Marco Sereno, Matthew Richardson, Ruth M. Saunders, Victoria C. Harris, Linzy Houchen-Wolloff, Neil J. Greening, Ewen M. Harrison, Annemarie B. Docherty, Nazir I. Lone, James D. Chalmers, Ling-Pei Ho, Alex Horsley, Michael Marks, Krisnah Poinasamy, Betty Raman, Rachael A. Evans, Louise V. Wain, Aziz Sheikh, Chris E. Brightling, Anthony De Soyza, Liam G. Heaney, J.K. Baillie, N.I. Lone, E. Pairo-Castineira, N. Avramidis, K. Rawlik, S Jones, L. Armstrong, B. Hairsine, H. Henson, C. Kurasz, A. Shaw, L. Shenton, H. Dobson, A. Dell, S. Fairbairn, N. Hawkings, J. Haworth, M. Hoare, V. Lewis, A. Lucey, G. Mallison, H. Nassa, C. Pennington, A. Price, C. Price, A. Storrie, G. Willis, S. Young, K. Poinasamy, S. Walker, I. Jarrold, A. Sanderson, K. Chong-James, C. David, W.Y. James, P. Pfeffer, O. Zongo, A. Martineau, C. Manisty, C. Armour, V. Brown, J. Busby, B. Connolly, T. Craig, S. Drain, L.G. Heaney, B. King, N. Magee, E. Major, D. McAulay, L. McGarvey, J. McGinness, T. Peto, R. Stone, A. Bolger, F. Davies, A. Haggar, J. Lewis, A. Lloyd, R. Manley, E. McIvor, D. Menzies, K. Roberts, W. Saxon, D. Southern, C. Subbe, V. Whitehead, A. Bularga, N.L. Mills, J. Dawson, H. El-Taweel, L. Robinson, L. Brear, K. Regan, D. Saralaya, K. Storton, S. Amoils, A. Bermperi, I. Cruz, K. Dempsey, A. Elmer, J. Fuld, H. Jones, S. Jose, S. Marciniak, M. Parkes, C. Ribeiro, J. Taylor, M. Toshner, L. Watson, J. Worsley, L. Broad, T. Evans, M. Haynes, L. Jones, L. Knibbs, A. McQueen, C. Oliver, K. Paradowski, R. Sabit, J. Williams, I. Jones, L. Milligan, E. Harris, C. Sampson, E. Davies, C. Evenden, A. Hancock, K. Hancock, C. Lynch, M. Rees, L. Roche, N. Stroud, T. Thomas-Woods, S. Heller, T. Chalder, K. Shah, E. Robertson, B. Young, M. Babores, M. Holland, N. Keenan, S. Shashaa, H. Wassall, L. Austin, E. Beranova, T. Cosier, J. Deery, T. Hazelton, H. Ramos, R. Solly, S. Turney, H. Weston, M. Ralser, L. Pearce, S. Pugmire, W. Stoker, A. Wilson, W. McCormick, E. Fraile, J. Ugoji, L. Aguilar Jimenez, G. Arbane, S. Betts, K. Bisnauthsing, A. Dewar, N. Hart, G. Kaltsakas, H. Kerslake, M.M. Magtoto, P. Marino, L.M. Martinez, M. Ostermann, J. Rossdale, T.S. Solano, M. Alvarez Corral, A. Arias, E. Bevan, D. Griffin, J. Martin, J. Owen, S. Payne, A. Prabhu, A. Reed, W. Storrar, N. Williams, C. Wrey Brown, T. Burdett, J. Featherstone, C. Lawson, A. Layton, C. Mills, L. Stephenson, Y. Ellis, P. Atkin, K. Brindle, M.G. Crooks, K. Drury, N. Easom, R. Flockton, L. Holdsworth, A. Richards, D.L. Sykes, S. Thackray-Nocera, C. Wright, S. Coetzee, K. Davies, R. Hughes, R. Loosley, H. McGuinness, A. Mohamed, L. O'Brien, Z. Omar, E. Perkins, J. Phipps, G. Ross, A. Taylor, H. Tench, R. Wolf-Roberts, L. Burden, E. Calvelo, B. Card, C. Carr, E.R. Chilvers, D. Copeland, P. Cullinan, P. Daly, L. Evison, T. Fayzan, H. Gordon, S. Haq, R.G. Jenkins, C. King, O. Kon, K. March, M. Mariveles, L. McLeavey, N. Mohamed, S. Moriera, U. Munawar, J. Nunag, U. Nwanguma, L. Orriss-Dib, A. Ross, M. Roy, E. Russell, K. Samuel, J. Schronce, N. Simpson, L. Tarusan, D.C. Thomas, C. Wood, N. Yasmin, D. Altmann, L.S. Howard, D. Johnston, A. Lingford-Hughes, W.D-C. Man, J. Mitchell, P.L. Molyneaux, C. Nicolaou, D.P. O'Regan, L. Price, J. Quint, D. Smith, R.S. Thwaites, J. Valabhji, S. Walsh, C.M. Efstathiou, F. Liew, A. Frankel, L. Lightstone, S. McAdoo, M. Wilkins, M. Willicombe, R. Touyz, A-M. Guerdette, M. Hewitt, R. Reddy, K. Warwick, S. White, A. McMahon, M. Malim, K. Bramham, M. Brown, K. Ismail, T. Nicholson, C. Pariante, C. Sharpe, S. Wessely, J. Whitney, O. Adeyemi, R. Adrego, H. Assefa-Kebede, J. Breeze, S. Byrne, P. Dulawan, A. Hoare, C.J. Jolley, A. Knighton, S. Patale, I. Peralta, N. Powell, A. Ramos, K. Shevket, F. Speranza, A. Te, A. Shah, A. Chiribiri, C. O'Brien, A. Hayday, A. Ashworth, P. Beirne, J. Clarke, C. Coupland, M. Dalton, C. Favager, J. Glossop, J. Greenwood, L. Hall, T. Hardy, A. Humphries, J. Murira, D. Peckham, S. Plein, J. Rangeley, G. Saalmink, A.L. Tan, E. Wade, B. Whittam, N. Window, J. Woods, G. Coakley, L. Turtle, L. Allerton, A.M. Allt, M. Beadsworth, A. Berridge, J. Brown, S. Cooper, A. Cross, S. Defres, S.L. Dobson, J. Earley, N. French, W. Greenhalf, K. Hainey, H.E. Hardwick, J. Hawkes, V. Highett, S. Kaprowska, A.L. Key, L. Lavelle-Langham, N. Lewis-Burke, G. Madzamba, F. Malein, S. Marsh, C. Mears, L. Melling, M.J. Noonan, L. Poll, J. Pratt, E. Richardson, A. Rowe, M.G. Semple, V. Shaw, K.A. Tripp, L.O. Wajero, S.A. Williams-Howard, D.G. Wootton, J. Wyles, S.N. Diwanji, S. Gurram, P. Papineni, S. Quaid, G.F. Tiongson, E. Watson, A. Briggs, M. Marks, C. Hastie, N. Rogers, N. Smith, D. Stensel, L. Bishop, K. McIvor, P. Rivera-Ortega, B. Al-Sheklly, C. Avram, J. Blaikely, M. Buch, N. Choudhury, D. Faluyi, T. Felton, T. Gorsuch, N.A. Hanley, A. Horsley, T. Hussell, Z. Kausar, N. Odell, R. Osbourne, K. Piper Hanley, K. Radhakrishnan, S. Stockdale, T. Kabir, J.T. Scott, P.J.M. Openshaw, I.D. Stewart, D. Burn, A. Ayoub, G. Burns, G. Davies, A. De Soyza, C. Echevarria, H. Fisher, C. Francis, A. Greenhalgh, P. Hogarth, J. Hughes, K. Jiwa, G. Jones, G. MacGowan, D. Price, A. Sayer, J. Simpson, H. Tedd, S. Thomas, S. West, M. Witham, S. Wright, A. Young, M.J. McMahon, P. Neill, D. Anderson, N. Basu, H. Bayes, A. Brown, A. Dougherty, K. Fallon, L. Gilmour, D. Grieve, K. Mangion, A. Morrow, R. Sykes, C. Berry, I.B. McInnes, K. Scott, F. Barrett, A. Donaldson, E.K. Sage, D. Bell, R. Hamil, K. Leitch, L. Macliver, M. Patel, J. Quigley, A. Smith, B. Welsh, G. Choudhury, S. Clohisey, A. Deans, A.B. Docherty, J. Furniss, E.M. Harrison, S. Kelly, A. Sheikh, J.D. Chalmers, D. Connell, C. Deas, A. Elliott, J. George, S. Mohammed, J. Rowland, A.R. Solstice, D. Sutherland, C.J. Tee, J. Bunker, R. Gill, R. Nathu, K. Holmes, H. Adamali, D. Arnold, S. Barratt, A. Dipper, S. Dunn, N. Maskell, A. Morley, L. Morrison, L. Stadon, S. Waterson, H. Welch, B. Jayaraman, T. Light, I. Vogiatzis, P. Almeida, C.E. Bolton, A. Hosseini, L. Matthews, R. Needham, K. Shaw, A.K. Thomas, J. Bonnington, M. Chrystal, C. Dupont, P.L. Greenhaff, A. Gupta, W. Jang, S. Linford, A. Nikolaidis, S. Prosper, A. Burns, N. Kanellakis, V.M. Ferreira, C. Nikolaidou, C. Xie, M. Ainsworth, A. Alamoudi, A. Bloss, P. Carter, M. Cassar, J. Chen, F. Conneh, T. Dong, R.I. Evans, E. Fraser, J.R. Geddes, F. Gleeson, P. Harrison, M. Havinden-Williams, L.P. Ho, P. Jezzard, I. Koychev, P. Kurupati, H. McShane, C. Megson, S. Neubauer, D. Nicoll, G. Ogg, E. Pacpaco, M. Pavlides, Y. Peng, N. Petousi, J. Pimm, N.M. Rahman, B. Raman, M.J. Rowland, K. Saunders, M. Sharpe, N. Talbot, E.M. Tunnicliffe, A. Korszun, S. Kerr, R.E. Barker, D. Cristiano, N. Dormand, P. George, M. Gummadi, S. Kon, K. Liyanage, C.M. Nolan, B. Patel, S. Patel, O. Polgar, P. Shah, S. Singh, J.A. Walsh, M. Gibbons, S. Ahmad, S. Brill, J. Hurst, H. Jarvis, L. Lim, S. Mandal, D. Matila, O. Olaosebikan, C. Singh, C. Laing, H. Baxendale, L. Garner, C. Johnson, J. Mackie, A. Michael, J. Newman, J. Pack, K. Paques, H. Parfrey, J. Parmar, A. Reddy, M. Halling-Brown, P. Dark, N. Diar-Bakerly, D. Evans, E. Hardy, A. Harvey, D. Holgate, S. Knight, N. Mairs, N. Majeed, L. McMorrow, J. Oxton, J. Pendlebury, C. Summersgill, R. Ugwuoke, S. Whittaker, W. Matimba-Mupaya, S. Strong-Sheldrake, P. Chowienczyk, J. Bagshaw, M. Begum, K. Birchall, R. Butcher, H. Carborn, F. Chan, K. Chapman, Y. Cheng, L. Chetham, C. Clark, Z. Coburn, J. Cole, M. Dixon, A. Fairman, J. Finnigan, H. Foot, D. Foote, A. Ford, R. Gregory, K. Harrington, L. Haslam, L. Hesselden, J. Hockridge, A. Holbourn, B. Holroyd-Hind, L. Holt, A. Howell, E. Hurditch, F. Ilyas, C. Jarman, A. Lawrie, J-H. Lee, E. Lee, R. Lenagh, A. Lye, I. Macharia, M. Marshall, A. Mbuyisa, J. McNeill, S. Megson, J. Meiring, L. Milner, S. Misra, H. Newell, T. Newman, C. Norman, L. Nwafor, D. Pattenadk, M. Plowright, J. Porter, P. Ravencroft, C. Roddis, J. Rodger, S.L. Rowland-Jones, P. Saunders, J. Sidebottom, J. Smith, L. Smith, N. Steele, G. Stephens, R. Stimpson, B. Thamu, A.A.R. Thompson, N. Tinker, K. Turner, H. Turton, P. Wade, J. Watson, I. Wilson, A. Zawia, L. Allsop, K. Bennett, P. Buckley, M. Flynn, M. Gill, C. Goodwin, M. Greatorex, H. Gregory, C. Heeley, L. Holloway, M. Holmes, J. Hutchinson, J. Kirk, W. Lovegrove, T.A. Sewell, S. Shelton, D. Sissons, K. Slack, S. Smith, D. Sowter, S. Turner, V. Whitworth, I. Wynter, J. Tomlinson, L. Warburton, S. Painter, S. Palmer, D. Redwood, J. Tilley, C. Vickers, T. Wainwright, G. Breen, M. Hotopf, R. Aul, D. Forton, M. Ali, A. Dunleavy, M. Mencias, N. Msimanga, T. Samakomva, S. Siddique, V. Tavoukjian, J. Teixeira, R. Ahmed, R. Francis, L. Connor, A. Cook, G.A. Davies, T. Rees, F. Thaivalappil, C. Thomas, M. McNarry, K.E. Lewis, M. Coulding, S. Kilroy, J. McCormick, J. McIntosh, V. Turner, J. Vere, A. Butt, H. Savill, S.S. Kon, G. Landers, H. Lota, S. Portukhay, M. Nasseri, A. Daniels, A. Hormis, J. Ingham, L. Zeidan, M. Chablani, L. Osborne, S. Aslani, A. Banerjee, R. Batterham, G. Baxter, R. Bell, A. David, E. Denneny, A.D. Hughes, W. Lilaonitkul, P. Mehta, A. Pakzad, B. Rangelov, B. Williams, J. Willoughby, M. Xu, N. Ahwireng, D. Bang, D. Basire, J.S. Brown, R.C. Chambers, A. Checkley, R. Evans, M. Heightman, T. Hillman, J. Jacob, R. Jastrub, M. Lipman, S. Logan, D. Lomas, M. Merida Morillas, H. Plant, J.C. Porter, K. Roy, E. Wall, T. Treibel, N. Ahmad Haider, C. Atkin, R. Baggott, M. Bates, A. Botkai, A. Casey, B. Cooper, J. Dasgin, C. Dawson, K. Draxlbauer, N. Gautam, J. Hazeldine, T. Hiwot, S. Holden, K. Isaacs, T. Jackson, V. Kamwa, D. Lewis, J.M. Lord, S. Madathil, C. McGhee, K. McGee, A. Neal, A. Newton-Cox, J. Nyaboko, D. Parekh, Z. Peterkin, H. Qureshi, L. Ratcliffe, E. Sapey, J. Short, T. Soulsby, J. Stockley, Z. Suleiman, T. Thompson, M. Ventura, S. Walder, C. Welch, D. Wilson, S. Yasmin, K.P. Yip, N. Chaudhuri, C. Childs, R. Djukanovic, S. Fletcher, M. Harvey, M.G. Jones, E. Marouzet, B. Marshall, R. Samuel, T. Sass, T. Wallis, H. Wheeler, R. Steeds, P. Beckett, C. Dickens, U. Nanda, M. Aljaroof, N. Armstrong, H. Arnold, H. Aung, M. Bakali, M. Bakau, E. Baldry, M. Baldwin, C. Bourne, M. Bourne, C.E. Brightling, N. Brunskill, P. Cairns, L. Carr, A. Charalambou, C. Christie, M.J. Davies, E. Daynes, S. Diver, R. Dowling, S. Edwards, C. Edwardson, O. Elneima, H. Evans, R.A. Evans, J. Finch, S. Finney, S. Glover, N. Goodman, B. Gooptu, N.J. Greening, K. Hadley, P. Haldar, B. Hargadon, V.C. Harris, L. Houchen-Wolloff, W. Ibrahim, L. Ingram, K. Khunti, A. Lea, D. Lee, H.J.C. McAuley, G.P. McCann, P. McCourt, T. McNally, G. Mills, W. Monteiro, M. Pareek, S. Parker, A. Prickett, I.N. Qureshi, A. Rowland, R. Russell, M. Sereno, A. Shikotra, S. Siddiqui, A. Singapuri, S.J. Singh, J. Skeemer, M. Soares, E. Stringer, S. Terry, T. Thornton, M. Tobin, T.J.C. Ward, F. Woodhead, T. Yates, A.J. Yousuf, B. Guillen Guiio, O.C. Leavy, L.V. Wain, M. Broome, P. McArdle, D. Thickett, R. Upthegrove, D. Wilkinson, P. Moss, D. Wraith, J. Evans, E. Bullmore, J.L. Heeney, C. Langenberg, W. Schwaeble, C. Summers, J. Weir McCall, D. Adeloye, D.E. Newby, R. Pius, I. Rudan, M. Shankar-Hari, C.L. Sudlow, M. Thorpe, S. Walmsley, B. Zheng, L. Allan, C. Ballard, A. McGovern, J. Dennis, J. Cavanagh, S. MacDonald, K. O'Donnell, J. Petrie, N. Sattar, M. Spears, E. Guthrie, M. Henderson, R.J. Allen, M. Bingham, T. Brugha, R. Free, D. Jones, L. Gardiner, A.J. Moss, E. Mukaetova-Ladinska, P. Novotny, C. Overton, J.E. Pearl, T. Plekhanova, M. Richardson, N. Samani, J. Sargent, M. Sharma, M. Steiner, C. Taylor, C. Tong, E. Turner, J. Wormleighton, B. Zhao, K. Ntotsis, R.M. Saunders, D. Lozano-Rojas, D. Cuthbertson, G. Kemp, A. McArdle, B. Michael, W. Reynolds, L.G. Spencer, B. Vinson, M. Ashworth, K. Abel, H. Chinoy, B. Deakin, M. Harvie, C.A. Miller, S. Stanel, P. Barran, D. Trivedi, H. McAllister-Williams, S. Paddick, A. Rostron, J.P. Taylor, D. Baguley, C. Coleman, E. Cox, L. Fabbri, S. Francis, I. Hall, E. Hufton, S. Johnson, F. Khan, P. Kitterick, R. Morriss, N. Selby, L. Wright, C. Antoniades, A. Bates, M. Beggs, K. Bhui, K. Breeze, K.M. Channon, D. Clark, X. Fu, M. Husain, X. Li, E. Lukaschuk, C. McCracken, K. McGlynn, R. Menke, K. Motohashi, T.E. Nichols, G. Ogbole, S. Piechnik, I. Propescu, J. Propescu, A.A. Samat, Z.B. Sanders, L. Sigfrid, M. Webster, L. Kingham, P. Klenerman, H. Lamlum, G. Carson, M. Taquet, L. Finnigan, L.C. Saunders, J.M. Wild, P.C. Calder, N. Huneke, G. Simons, D. Baldwin, S. Bain, L. Daines, E. Bright, P. Crisp, R. Dharmagunawardena, M. Stern, L. Bailey, A. Reddington, A. Wight, A. Ashish, J. Cooper, E. Robinson, A. Broadley, L. Barman, C. Brookes, K. Elliott, L. Griffiths, Z. Guy, K. Howard, D. Ionita, H. Redfearn, C. Sarginson, and A. Turnbull
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Medicine - Abstract
Background The long-term outcomes of COVID-19 hospitalisation in individuals with pre-existing airway diseases are unknown. Methods Adult participants hospitalised for confirmed or clinically suspected COVID-19 and discharged between 5 March 2020 and 31 March 2021 were recruited to the Post-hospitalisation COVID-19 (PHOSP-COVID) study. Participants attended research visits at 5 months and 1 year post discharge. Clinical characteristics, perceived recovery, burden of symptoms and health-related quality of life (HRQoL) of individuals with pre-existing airway disease (i.e., asthma, COPD or bronchiectasis) were compared to the non-airways group. Results A total of 615 out of 2697 (22.8%) participants had a history of pre-existing airway diseases (72.0% diagnosed with asthma, 22.9% COPD and 5.1% bronchiectasis). At 1 year, the airways group participants were less likely to feel fully recovered (20.4% versus 33.2%, p
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37. Peer review of the pesticide risk assessment for the active substance difenoconazole in light of confirmatory data submitted
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European Food Safety Authority (EFSA), Fernando Álvarez, Maria Arena, Domenica Auteri, Sofia Batista Leite, Marco Binaglia, Anna Federica Castoldi, Arianna Chiusolo, Angelo Colagiorgi, Mathilde Colas, Federica Crivellente, Chloe De Lentdecker, Isabella De Magistris, Mark Egsmose, Gabriella Fait, Franco Ferilli, German Giner Santonja, Varvara Gouliarmou, Katrin Halling, Laia Herrero Nogareda, Alessio Ippolito, Frederique Istace, Samira Jarrah, Dimitra Kardassi, Aude Kienzler, Anna Lanzoni, Roberto Lava, Renata Leuschner, Alberto Linguadoca, Jochem Louisse, Christopher Lythgo, Oriol Magrans, Iris Mangas, Galini Mavriou, Andrea Mioč, Ileana Miron, Tunde Molnar, Laura Padovani, Vincenzo Padricello, Martina Panzarea, Juan Manuel Parra Morte, Simone Rizzuto, Anamarija Romac, Agnès Rortais, Miguel Santos, Rositsa Serafimova, Rachel Sharp, Csaba Szentes, Andrea Terron, Anne Theobald, Manuela Tiramani, Giorgia Vianello, and Laura Villamar‐Bouza
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confirmatory data ,difenoconazole ,fungicide ,peer review ,pesticide ,risk assessment ,Nutrition. Foods and food supply ,TX341-641 ,Chemical technology ,TP1-1185 - Abstract
Abstract The conclusions of the EFSA following the peer review of the initial risk assessment carried out by the competent authority of the rapporteur Member State, Spain, for the pesticide active substance difenoconazole are reported. The context of the peer review was that requested by the European Commission following the submission and evaluation of confirmatory information with regard to the consumer risk assessment. The conclusions were reached on the basis of the evaluation of the representative uses of difenoconazole as a fungicide on pome fruit, carrot, wheat, barley, triticale, rye and oats. The reliable endpoints concluded as being appropriate for use in regulatory risk assessment, derived from the available studies and/or literature in the dossier peer reviewed, are presented. Concerns were not identified.
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- 2024
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38. Peer review of the pesticide risk assessment of the active substance mepiquat (evaluated variant mepiquat chloride)
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European Food Safety Authority (EFSA), Fernando Álvarez, Maria Arena, Domenica Auteri, Sofia Batista Leite, Marco Binaglia, Anna Federica Castoldi, Arianna Chiusolo, Angelo Colagiorgi, Mathilde Colas, Federica Crivellente, Chloe De Lentdecker, Isabella De Magistris, Mark Egsmose, Gabriella Fait, Franco Ferilli, German Giner Santonja, Varvara Gouliarmou, Katrin Halling, Laia Herrero Nogareda, Alessio Ippolito, Frederique Istace, Samira Jarrah, Dimitra Kardassi, Aude Kienzler, Anna Lanzoni, Roberto Lava, Renata Leuschner, Alberto Linguadoca, Jochem Louisse, Christopher Lythgo, Oriol Magrans, Iris Mangas, Galini Mavriou, Andrea Mioč, Ileana Miron, Tunde Molnar, Laura Padovani, Vincenzo Padricello, Martina Panzarea, Juan Manuel Parra Morte, Simone Rizzuto, Anamarija Romac, Agnès Rortais, Miguel Santos, Rositsa Serafimova, Rachel Sharp, Csaba Szentes, Andrea Terron, Anne Theobald, Manuela Tiramani, Giorgia Vianello, and Laura Villamar‐Bouza
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mepiquat ,mepiquat chloride ,peer review ,pesticide ,plant growth regulator ,risk assessment ,Nutrition. Foods and food supply ,TX341-641 ,Chemical technology ,TP1-1185 - Abstract
Abstract The conclusions of the EFSA following the peer review of the initial risk assessments carried out by the competent authorities of the rapporteur Member State, Finland, and co‐rapporteur Member State, Estonia, for the pesticide active substance mepiquat (evaluated variant mepiquat chloride) are reported. The context of the peer review was that required by Commission Implementing Regulation (EU) No 844/2012, as amended by Commission Implementing Regulation (EU) No 2018/1659. The conclusions were reached on the basis of the evaluation of the representative uses of mepiquat chloride as a plant growth regulator on cereals and grass (field uses). The reliable end points, appropriate for use in regulatory risk assessment, are presented. Missing information identified as being required by the regulatory framework is listed. Concerns are identified.
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- 2024
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39. Peer review of the pesticide risk assessment of the active substance lenacil
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European Food Safety Authority (EFSA), Fernando Álvarez, Maria Arena, Domenica Auteri, Sofia Batista Leite, Marco Binaglia, Anna Federica Castoldi, Arianna Chiusolo, Angelo Colagiorgi, Mathilde Colas, Federica Crivellente, Chloe De Lentdecker, Isabella De Magistris, Mark Egsmose, Gabriella Fait, Franco Ferilli, German Giner Santonja, Varvara Gouliarmou, Katrin Halling, Laia Herrero Nogareda, Alessio Ippolito, Frederique Istace, Samira Jarrah, Dimitra Kardassi, Aude Kienzler, Anna Lanzoni, Roberto Lava, Renata Leuschner, Alberto Linguadoca, Jochem Louisse, Christopher Lythgo, Oriol Magrans, Iris Mangas, Galini Mavriou, Andrea Mioč, Ileana Miron, Tunde Molnar, Laura Padovani, Vincenzo Padricello, Martina Panzarea, Juan Manuel Parra Morte, Simone Rizzuto, Anamarija Romac, Agnès Rortais, Miguel Santos, Rositsa Serafimova, Rachel Sharp, Csaba Szentes, Andrea Terron, Anne Theobald, Manuela Tiramani, Giorgia Vianello, and Laura Villamar‐Bouza
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herbicide ,lenacil ,peer review ,pesticide ,risk assessment ,Nutrition. Foods and food supply ,TX341-641 ,Chemical technology ,TP1-1185 - Abstract
Abstract The conclusions of the European Food Safety Authority (EFSA) following the peer review of the initial risk assessments carried out by the competent authorities of the rapporteur Member State, Belgium, and co‐rapporteur Member State, Austria, for the pesticide active substance lenacil are reported. The context of the peer review was that required by Commission Implementing Regulation (EU) No 844/2012, as amended by Commission Implementing Regulation (EU) No 2018/1659. The conclusions were reached on the basis of the evaluation of the representative uses of lenacil as a herbicide on sugar and fodder beet (field use). The reliable end points, appropriate for use in regulatory risk assessment, are presented. Missing information identified as being required by the regulatory framework is listed. Concerns are reported where identified.
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- 2024
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40. Sustainable Lifestyle Among Office Workers (the SOFIA Study): Protocol for a Cluster Randomized Controlled Trial
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Katarina Bälter, Abby C King, Johanna Fritz, Annika Tillander, and Oskar Halling Ullberg
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Medicine ,Computer applications to medicine. Medical informatics ,R858-859.7 - Abstract
BackgroundSociety is facing multiple challenges, including lifestyle- and age-related diseases of major public health relevance, and this is of particular importance when the general population, as well as the workforce, is getting older. In addition, we are facing global climate change due to extensive emissions of greenhouse gases and negative environmental effects. A lifestyle that promotes healthy life choices as well as climate and environmentally friendly decisions is considered a sustainable lifestyle. ObjectiveThis study aims to evaluate if providing information about a sustainable lifestyle encourages individuals to adopt more nutritious dietary habits and increase physical activity, as compared to receiving information solely centered around health-related recommendations for dietary intake and physical activity by the Nordic Nutrition Recommendations and the World Health Organization. Novel features of this study include the use of the workplace as an arena for health promotion, particularly among office workers—a group known to be often sedentary at work and making up 60% of all employees in Sweden. MethodsThe Sustainable Office Intervention (SOFIA) study is a 2-arm, participant-blinded, cluster randomized controlled trial that includes a multilevel sustainable lifestyle arm (intervention arm, n=19) and a healthy lifestyle arm (control arm, n=14). The eligibility criteria were being aged 18-65 years and doing office work ≥20 hours per week. Both intervention arms are embedded in the theoretically based behavioral change wheel method. The intervention study runs for approximately 8 weeks and contains 6 workshops. The study focuses on individual behavior change as well as environmental and policy features at an organizational level to facilitate or hinder a sustainable lifestyle at work. Through implementing a citizen science methodology within the trial, the participants (citizen scientists) collect data using the Stanford Our Voice Discovery Tool app and are involved in analyzing the data, formulating a list of potential actions to bring about feasible changes in the workplace. ResultsParticipant recruitment and data collection began in August 2022. As of June 2024, a total of 37 participants have been recruited. The results of the pilot phase are expected to be published in 2024 or 2025. ConclusionsGiven the ongoing climate change, negative environmental effects, and the global epidemic of metabolic diseases, a sustainable lifestyle among office workers holds important potential to help in counteracting this trend. Thus, there is an urgent unmet need to test the impact of a sustainable lifestyle on food intake, physical activity, and environmental and climate impacts in a worksite-based randomized controlled trial. This study protocol responds to a societal need by addressing multilevel aspects, including individual behavior changes as well as environmental and organizational changes of importance for the successful implementation of sustainable lifestyle habits in an office setting. International Registered Report Identifier (IRRID)DERR1-10.2196/57777
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41. The course of borderline personality disorder from adolescence to early adulthood: A 5-year follow-up study
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Mie Sedoc Jørgensen, Lise Møller, Sune Bo, Mickey Kongerslev, Lene Halling Hastrup, Andrew Chanen, Ole Jakob Storebø, Stig Poulsen, Emma Beck, and Erik Simonsen
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Borderline personality disorder ,Follow-up ,Adolescence ,Psychopathology ,Early intervention ,Psychiatry ,RC435-571 - Abstract
Background: Studies of the medium- to long-term clinical and functional course for treatment-seeking adolescents with borderline personality disorder (BPD) are lacking. This study aims to outline the psychopathological and functional status of participants, five years after being diagnosed with BPD during adolescence. Methods: Participants were originally enrolled in a randomized clinical trial that compared mentalization-based group treatment with treatment as usual for adolescents with BPD. Semi-structured interview assessments at five-year follow-up included the Schedules for Clinical Assessment in Neuropsychiatry and the Structured Clinical Interview for DSM-5 Personality Disorders. Attention deficit hyperactivity disorder (ADHD), alcohol, substance and tobacco use, posttraumatic stress disorder (PTSD), complex PTSD, and general functioning were assessed using self-report instruments. Results: 97 of the original sample of 111 participants (87%) participated. They were aged 19–23 years. The most prevalent disorders were ADHD (59%), any personality disorder (47%) of which half continued to meet criteria for BPD (24%), anxiety disorders (37%), depressive disorders (32%), PTSD or complex PTSD (20%), schizophrenia (16%), and eating disorders (13%). Only 16% did not meet criteria for any mental disorder. Approximately half of the sample were in psychological and/or psychopharmacological treatment at the time of follow-up. Their general functioning remained impaired, with 36% not engaged in education, employment or training (NEET), which is nearly four times the rate of NEET in the same age group in the general population. Conclusions: Although stability of the categorical BPD diagnosis is modest, adolescents meeting diagnostic criteria for BPD show a broad range of poor outcomes at five-year follow-up. BPD appears to be a marker of general maladjustment during adolescence and a harbinger of severe problems during the transition to young adulthood. Early intervention programs for adolescents diagnosed with BPD should focus upon a broad range of functional and psychopathological outcomes, especially social and vocational support, rather than the narrow BPD diagnosis.
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- 2024
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42. Using citizen science to explore barriers and facilitators for healthy and sustainable lifestyles in office environments
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Ullberg, Oskar Halling, Toivanen, Susanna, King, Abby C., and Bälter, Katarina
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- 2024
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43. Contact X-ray Brachytherapy as a sole treatment in selected patients with early rectal cancer – Multi-centre study
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Wah Than, Ngu, Mark Pritchard, D., Hughes, David M., Shing Yu, Kai, Minnaar, Helen S., Dhadda, Amandeep, Mills, Jamie, Folkesson, Joakim, Radu, Calin, Duckworth, C.A., Wong, Helen, Ul Haq, Muneeb, Sripadam, Rajaram, Halling-Brown, Mark D., Stewart, Alexandra J., and Sun Myint, Arthur
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- 2024
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44. Cognitive and psychiatric symptom trajectories 2–3 years after hospital admission for COVID-19: a longitudinal, prospective cohort study in the UK
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Lone, Nazir, Baillie, Kenneth, Pairo-Castineira, Erola, Avramidis, Nikos, Wain, Louise, Guillen-Guio, Beatriz, Leavy, Olivia, Jones, S, Armstrong, Lisa, Hairsine, Brigid, Henson, Helen, Kurasz, Claire, Shaw, Alison, Shenton, Liz, Dobson, Hannah, Dell, Amanda, Fairbairn, Sara, Hawkings, Nancy, Haworth, Jill, Hoare, Michaela, Lewis, Victoria, Lucey, Alice, Mallison, Georgia, Nassa, Heeah, Pennington, Chris, Price, Andrea, Price, Claire, Storrie, Andrew, Willis, Gemma, Young, Susan, Poinasamy, Krisnah, Walker, Samantha, Jarrold, Ian, Rawlik, Konrad, Sanderson, Amy, Chong-James, K, David, C, James, W Y, Pfeffer, Paul, Zongo, O, Martineau, Adrian, Manisty, C, Armour, Cherie, Brown, Vanessa, Busby, John, Connolly, Bronwen, Craig, Thelma, Drain, Stephen, Heaney, Liam, King, Bernie, Magee, Nick, Major, E, McAulay, Danny, McGarvey, Lorcan, McGinness, Jade, Peto, Tunde, Stone, Roisin, Bolger, Annette, Davies, Ffyon, Haggar, Ahmed, Lewis, Joanne, Lloyd, Arwel, Manley, R, McIvor, Emma, Menzies, Daniel, Roberts, K, Saxon, W, Southern, David, Subbe, Christian, Whitehead, Victoria, Bularga, Anda, Mills, Nicholas, Dawson, Joy, El-Taweel, Hosni, Robinson, Leanne, Brear, Lucy, Regan, Karen, Saralaya, Dinesh, Storton, Kim, Amoils, Shannon, Bermperi, Areti, Cruz, Isabel, Dempsey, K, Elmer, Anne, Fuld, Jonathon, Jones, H, Jose, Sherly, Marciniak, Stefan, Parkes, M, Ribeiro, Carla, Taylor, Jessica, Toshner, Mark, Watson, L, Worsley, J, Broad, Lauren, Evans, Teriann, Haynes, Matthew, Jones, L, Knibbs, Lucy, McQueen, Alison, Oliver, Catherine, Paradowski, Kerry, Sabit, Ramsey, Williams, Jenny, Jones, Ian, Milligan, Lea, Harris, Edward, Sampson, Claire, Davies, Ellie, Evenden, Cerys, Hancock, Alyson, Hancock, Kia, Lynch, Ceri, Rees, Meryl, Roche, Lisa, Stroud, Natalie, Thomas-Woods, T, Heller, Simon, Chalder, Trudie, Shah, Kamini, Robertson, Elizabeth, Young, Bob, Babores, Marta, Holland, Maureen, Keenan, Natalie, Shashaa, Sharlene, Wassall, Helen, Austin, Liam, Beranova, Eva, Cosier, Tracey, Deery, Joanne, Hazelton, Tracy, Price, Carly, Ramos, Hazel, Solly, Reanne, Turney, Sharon, Weston, Heather, Coughlan, Eamon, Ralser, Markus, Pearce, Lorraine, Pugmire, S, Stoker, Wendy, Wilson, Ann, McCormick, W, Fraile, Eva, Ugoji, Jacinta, Aguilar Jimenez, Laura, Arbane, Gill, Betts, Sarah, Bisnauthsing, Karen, Dewar, A, Hart, Nicholas, Kaltsakas, G, Kerslake, Helen, Magtoto, Murphy, Marino, Philip, Martinez, L M, Ostermann, Marlies, Rossdale, Jennifer, Solano, Teresa, Alvarez Corral, Maria, Arias, Ava Maria, Bevan, Emily, Griffin, Denise, Martin, Jane, Owen, J, Payne, Sheila, Prabhu, A, Reed, Annabel, Storrar, Will, Williams, Nick, Wrey Brown, Caroline, Burdett, Tracy, Featherstone, James, Lawson, Cathy, Layton, Alison, Mills, Clare, Stephenson, Lorraine, Ellis, Yvette, Atkin, Paul, Brindle, K, Crooks, Michael, Drury, Katie, Easom, Nicholas, Flockton, Rachel, Holdsworth, L, Richards, A, Sykes, D L, Thackray-Nocera, Susannah, Wright, C, Coetzee, S, Davies, Kim, Hughes, Rachel Ann, Loosley, Ronda, McGuinness, Heather, Mohamed, Abdelrahman, O'Brien, Linda, Omar, Zohra, Perkins, Emma, Phipps, Janet, Ross, Gavin, Taylor, Abigail, Tench, Helen, Wolf-Roberts, Rebecca, Burden, L, Calvelo, Ellen, Card, Bethany, Carr, Caitlin, Chilvers, Edwin, Copeland, Donna, Cullinan, P, Daly, Patrick, Evison, Lynsey, Fayzan, Tamanah, Gordon, Hussain, Haq, Sulaimaan, Jenkins, Gisli, King, Clara, Kon, Onn Min, March, Katherine, Mariveles, Myril, McLeavey, Laura, Mohamed, Noura, Moriera, Silvia, Munawar, Unber, Nunag, Jose Lloyd, Nwanguma, Uchechi, Orriss-Dib, Lorna, Ross, Alexandra, Roy, Maura, Russell, Emily, Samuel, Katherine, Schronce, J, Simpson, Neil, Tarusan, Lawrence, Thomas, David, Wood, Chloe, Yasmin, Najira, Altmann, Danny, Howard, Luke, Johnston, Desmond, Lingford-Hughes, Anne, Man, William, Mitchell, Jane, Molyneaux, Philip, Nicolaou, Christos, O'Regan, D P, Price, L, Quint, Jenni, Smith, David, Thwaites, Ryan, Valabhji, Jonathon, Walsh, Simon, Efstathiou, Claudia, Liew, Felicity, Frankel, Anew, Lightstone, Liz, McAdoo, Steve, Wilkins, Martin, Willicombe, Michelle, Touyz, R, Guerdette, Anne-Marie, Hewitt, Melanie, Reddy, R, Warwick, Katie, White, Sonia, McMahon, Aisling, Adeyemi, Oluwaseun, Adrego, Rita, Assefa-Kebede, Hosanna, Breeze, Jonathon, Byrne, S, Dulawan, Pearl, Hoare, Amy, Jolley, Caroline, Knighton, Abigail, Patale, Sheetal, Peralta, Ida, Powell, Natassia, Ramos, Albert, Shevket, K, Speranza, Fabio, Te, Amelie, Malim, M, Bramham, Kate, Brown, M, Ismail, Khalida, Nicholson, Tim, Pariante, Carmen, Sharpe, Claire, Wessely, Simon, Whitney, J, Shah, Ajay, Chiribiri, A, O'Brien, C, Hayday, A, Ashworth, Andrew, Beirne, Paul, Clarke, Jude, Coupland, C, Dalton, Matthhew, Favager, Clair, Glossop, Jodie, Greenwood, John, Hall, Lucy, Hardy, Tim, Humphries, Amy, Murira, Jennifer, Peckham, Dan, Plein, S, Rangeley, Jade, Saalmink, Gwen, Tan, Ai Lyn, Wade, Elaine, Whittam, Beverley, Window, Nicola, Woods, Janet, Coakley, G, Turtle, Lance, Allerton, Lisa, Allt, Ann Marie, Beadsworth, M, Berridge, Anthony, Brown, Jo, Cooper, Shirley, Cross, Andy, Defres, Sylviane, Dobson, S L, Earley, Joanne, French, N, Greenhalf, William, Hainey, Kera, Hardwick, Hayley, Hawkes, Jenny, Highett, Victoria, Kaprowska, Sabina, Key, Angela, Lavelle-Langham, Lara, Lewis-Burke, N, Madzamba, Gladys, Malein, Flora, Marsh, Sophie, Mears, Chloe, Melling, Lucy, Noonan, Matthew, Poll, L, Pratt, James, Richardson, Emma, Rowe, Anna, Semple, Calum, Shaw, Victoria, Tripp, K A, Wajero, Lilian, Williams-Howard, S A, Wootton, Dan, Wyles, J, Diwanji, Shalin, Gurram, Sambasivarao, Papineni, Padmasayee, Quaid, Sheena, Tiongson, Gerlynn, Watson, Ekaterina, Briggs, Andrew, Marks, Michael, Hastie, Claire, Rogers, Natalie, Smith, Nikki, Stensel, David, Bishop, Lettie, McIvor, Katherine, Rivera-Ortega, Pilar, Al-Sheklly, Bashar, Avram, Cristina, Blaikely, John, Buch, M, Choudhury, N, Faluyi, David, Felton, T, Gorsuch, T, Hanley, Neil, Horsley, Alex, Hussell, Tracy, Kausar, Zunaira, Odell, Natasha, Osbourne, Rebecca, Piper Hanley, Karen, Radhakrishnan, K, Stockdale, Sue, Kabir, Thomas, Scott, Janet, Stewart, Iain, Openshaw, Peter, Burn, David, Ayoub, A, Brown, J, Burns, G, Davies, Gareth, De Soyza, Anthony, Echevarria, Carlos, Fisher, Helen, Francis, C, Greenhalgh, Alan, Hogarth, Philip, Hughes, Joan, Jiwa, Kasim, Jones, G, MacGowan, G, Price, D, Sayer, Avan, Simpson, John, Tedd, H, Thomas, S, West, Sophie, Witham, M, Wright, S, Young, A, McMahon, Michael, Neill, Paula, Anderson, David, Basu, Neil, Bayes, Hannah, Brown, Ammani, Dougherty, Andrew, Fallon, K, Gilmour, L, Grieve, D, Mangion, K, Morrow, A, Sykes, R, Berry, Colin, McInnes, I B, Scott, Kathryn, Barrett, Fiona, Donaldson, A, Sage, Beth, Bell, Murdina, Brown, Angela, Hamil, R, Leitch, Karen, Macliver, L, Patel, Manish, Quigley, Jackie, Smith, Andrew, Welsh, B, Choudhury, Gaunab, Clohisey, S, Deans, Andrew, Docherty, Annemarie, Furniss, J, Harrison, Ewen, Kelly, S, Sheikh, Aziz, Chalmers, James, Connell, David, Deas, C, Elliott, Anne, George, J, Mohammed, S, Rowland, J, Solstice, AR, Sutherland, Debbie, Tee, Caroline, Bunker, Jenny, Gill, Rhyan, Nathu, Rashmita, Holmes, Katie, Adamali, H, Arnold, David, Barratt, Shaney, Dipper, A, Dunn, Sarah, Maskell, Nick, Morley, Anna, Morrison, Leigh, Stadon, Louise, Waterson, Samuel, Welch, H, Jayaraman, Bhagy, Light, Tessa, Vogiatzis, Ioannis, Almeida, Paula, Bolton, Charlotte, Hosseini, Akram, Matthews, Laura, Needham, Robert, Shaw, Karen, Thomas, Andrew, Bonnington, J, Chrystal, Melanie, Dupont, Catherine, Greenhaff, Paul, Gupta, Ayushman, Jang, W, Linford, S, Nikolaidis, Athanasios, Prosper, Sabrina, Burns, A, Kanellakis, N, Ferreira, V, Nikolaidou, C, Xie, C, Ainsworth, Mark, Alamoudi, Asma, Bloss, Angela, Carter, Penny, Cassar, M, Chen, Jin, Conneh, Florence, Dong, T, Evans, Ranuromanana, Fraser, Emily, Geddes, John, Gleeson, F, Harrison, Paul, Havinden-Williams, May, Ho, Ling Pei, Jezzard, P, Koychev, Ivan, Kurupati, Prathiba, McShane, H, Megson, Clare, Neubauer, Stefan, Nicoll, Debby, Ogg, G, Pacpaco, Edmund, Pavlides, M, Peng, Yanchun, Petousi, Nayia, Pimm, John, Rahman, Najib, Raman, Betty, Rowland, M J, Saunders, Kathryn, Sharpe, Michael, Talbot, Nick, Tunnicliffe, E M, Korszun, Ania, Kerr, Steven, Barker, R E, Cristiano, Daniele, Dormand, N, George, P, Gummadi, Mahitha, Kon, S, Liyanage, Kamal, Nolan, C M, Patel, B, Patel, Suhani, Polgar, Oliver, Shah, P, Singh, Suver, Walsh, J A, Gibbons, Michael, Ahmad, Shanaz, Brill, Simon, Hurst, John, Jarvis, Hannah, Lim, Lai, Mandal, S, Matila, Darwin, Olaosebikan, Olaoluwa, Singh, Claire, Laing, C, Baxendale, Helen, Garner, Lucie, Johnson, C, Mackie, J, Michael, Alice, Newman, J, Pack, Jamie, Paques, K, Parfrey, H, Parmar, J, Reddy, A, Halling-Brown, Mark, Dark, P, Diar-Bakerly, Nawar, Evans, D, Hardy, E, Harvey, Alice, Holgate, D, Knight, Sean, Mairs, N, Majeed, N, McMorrow, L, Oxton, J, Pendlebury, Jessica, Summersgill, C, Ugwuoke, R, Whittaker, S, Matimba-Mupaya, Wadzanai, Strong-Sheldrake, Sophia, Chowienczyk, Phillip, Bagshaw, J, Begum, M, Birchall, K, Butcher, Robyn, Carborn, H, Chan, Flora, Chapman, Kerry, Cheng, Yutung, Chetham, Luke, Clark, Cameron, Coburn, Zach, Cole, Joby, Dixon, Myles, Fairman, Alexandra, Finnigan, J, Foot, H, Foote, David, Ford, Amber, Gregory, Rebecca, Harrington, Kate, Haslam, L, Hesselden, L, Hockridge, J, Holbourn, Ailsa, Holroyd-Hind, B, Holt, L, Howell, Alice, Hurditch, E, Ilyas, F, Jarman, Claire, Lawrie, Allan, Lee, Ju Hee, Lee, Elvina, Lenagh, Rebecca, Lye, Alison, Macharia, Irene, Marshall, M, Mbuyisa, Angeline, McNeill, J, Megson, Sharon, Meiring, J, Milner, L, Misra, S, Newell, Helen, Newman, Tom, Norman, C, Nwafor, Lorenza, Pattenadk, Dibya, Plowright, Megan, Porter, Julie, Ravencroft, Phillip, Roddis, C, Rodger, J, Rowland-Jones, Sarah, Saunders, Peter, Sidebottom, J, Smith, Jacqui, Smith, Laurie, Steele, N, Stephens, G, Stimpson, R, Thamu, B, Thompson, A. A. Roger, Tinker, N, Turner, Kim, Turton, Helena, Wade, Phillip, Walker, S, Watson, James, Wilson, Imogen, Zawia, Amira, Allsop, Lynne, Bennett, Kaytie, Buckley, Phil, Flynn, Margaret, Gill, Mandy, Goodwin, Camelia, Greatorex, M, Gregory, Heidi, Heeley, Cheryl, Holloway, Leah, Holmes, Megan, Hutchinson, John, Kirk, Jill, Lovegrove, Wayne, Sewell, Terri Ann, Shelton, Sarah, Sissons, D, Slack, Katie, Smith, Susan, Sowter, D, Turner, Sarah, Whitworth, V, Wynter, Inez, Tomlinson, Johanne, Warburton, Louise, Painter, Sharon, Palmer, Sue, Redwood, Dawn, Tilley, Jo, Vickers, Carinna, Wainwright, Tania, Breen, G, Hotopf, M, Aul, Raminder, Forton, D, Ali, Mariam, Dunleavy, A, Mencias, Mark, Msimanga, N, Samakomva, T, Siddique, Sulman, Tavoukjian, Vera, Teixeira, J, Ahmed, Rubina, Francis, Richard, Connor, Lynda, Cook, Amanda, Davies, Gwyneth, Rees, Tabitha, Thaivalappil, Favas, Thomas, Caradog, McNarry, M, Williams, N, Lewis, Keir, Coulding, Martina, Jones, Heather, Kilroy, Susan, McCormick, Jacqueline, McIntosh, Jerome, Turner, Victoria, Vere, Joanne, Butt, Al-Tahoor, Savill, Heather, Kon, Samantha, Landers, G, Lota, Harpreet, Portukhay, Sofiya, Nasseri, Mariam, Daniels, Alison, Hormis, Anil, Ingham, Julie, Zeidan, Lisa, Chablani, Manish, Osborne, Lynn, Aslani, Shahab, Banerjee, Amita, Batterham, R, Baxter, Gabrielle, Bell, Robert, David, Anthony, Denneny, Emma, Hughes, Alun, Lilaonitkul, W, Mehta, P, Pakzad, Ashkan, Rangelov, Bojidar, Williams, B, Willoughby, James, Xu, Moucheng, Ahwireng, Nyarko, Bang, Dongchun, Basire, Donna, Brown, Jeremy, Chambers, Rachel, Checkley, A, Evans, R, Heightman, M, Hillman, T, Jacob, Joseph, Jastrub, Roman, Lipman, M, Logan, S, Lomas, D, Merida Morillas, Marta, Plant, Hannah, Porter, Joanna, Roy, K, Wall, E, Treibel, T, Ahmad Haider, N, Atkin, Catherine, Baggott, Rhiannon, Bates, Michelle, Botkai, A, Casey, Anna, Cooper, B, Dasgin, Joanne, Dawson, Camilla, Draxlbauer, Katharine, Gautam, N, Hazeldine, J, Hiwot, T, Holden, Sophie, Isaacs, Karen, Jackson, T, Kamwa, Vicky, Lewis, D, Lord, Janet, Madathil, S, McGee, C, Mcgee, K, Neal, Aoife, Newton-Cox, Alex, Nyaboko, Joseph, Parekh, Dhruv, Peterkin, Z, Qureshi, H, Ratcliffe, Liz, Sapey, Elizabeth, Short, J, Soulsby, Tracy, Stockley, J, Suleiman, Zehra, Thompson, Tamika, Ventura, Maximina, Walder, Sinead, Welch, Carly, Wilson, Daisy, Yasmin, S, Yip, Kay Por, Chaudhuri, N, Childs, Caroline, Djukanovic, R, Fletcher, S, Harvey, Matt, Jones, Mark, Marouzet, Elizabeth, Marshall, B, Samuel, Reena, Sass, T, Wallis, Tim, Wheeler, Helen, Steeds, R, Beckett, Paul, Dickens, Caroline, Nanda, Uttam, Aljaroof, M, Armstrong, Natalie, Arnold, H, Aung, Hnin, Bakali, Majda, Bakau, M, Baldry, E, Baldwin, Molly, Bourne, Charlotte, Bourne, Michelle, Brightling, Chris, Brunskill, Nigel, Cairns, P, Carr, Liesel, Charalambou, Amanda, Christie, C, Davies, Melanie, Daynes, Enya, Diver, Sarah, Dowling, Rachael, Edwards, Sarah, Edwardson, C, Elneima, Omer, Evans, H, Evans, Rachael, Finch, J, Glover, Sarah, Goodman, Nicola, Gooptu, Bibek, Greening, Neil, Hadley, Kate, Haldar, Pranab, Hargadon, Beverley, Harris, Victoria, Houchen-Wolloff, Linzy, Ibrahim, W, Ingram, L, Khunti, Kamlesh, Lea, A, Lee, D, McAuley, Hamish, McCann, Gerry, McCourt, P, Mcnally, Teresa, Mills, George, Monteiro, Will, Pareek, Manish, Parker, S, Prickett, Anne, Qureshi, I N, Rowland, A, Russell, Richard, Sereno, Marco, Shikotra, Aarti, Siddiqui, Salman, Singapuri, Ananga, Singh, Sally, Skeemer, J, Soares, M, Stringer, E, Thornton, T, Tobin, Martin, Ward, T J C, Woodhead, F, Yates, Tom, Yousuf, A J, Broome, Mattew, McArdle, Paul, Thickett, David, Upthegrove, Rachel, Wilkinson, Dan, Moss, Paul, Wraith, David, Evans, Jonathon, Bullmore, Ed, Heeney, Jonathon, Langenberg, Claudia, Schwaeble, William, Summers, Charlotte, Weir McCall, J, Adeloye, Davies, Newby, D E, Pius, Riinu, Rudan, Igor, Shankar-Hari, Manu, Sudlow, Catherine, Thorpe, Mat, Walmsley, Sarah, Zheng, Bang, Allan, Louise, Ballard, Clive, McGovern, Andrew, Dennis, J, Cavanagh, Jonathon, MacDonald, S, O'Donnell, Kate, Petrie, John, Sattar, Naveed, Spears, Mark, Guthrie, Elspeth, Henderson, Max, Allen, Richard, Bingham, Michelle, Brugha, Terry, Finney, Selina, Free, Rob, Jones, Don, Lawson, Claire, Lucy, Gardiner, Moss, Alistair, Mukaetova-Ladinska, Elizabeta, Novotny, Petr, Overton, Charlotte, Pearl, John, Plekhanova, Tatiana, Richardson, M, Samani, Nilesh, Sargant, Jack, Sharma, M, Steiner, Mike, Taylor, Chris, Terry, Sarah, Tong, C, Turner, E, Wormleighton, J, Zhao, Bang, Ntotsis, Kimon, Saunders, Ruth, Lozano-Rojas, Daniel, Goemans, Anne, Cuthbertson, D, Kemp, G, McArdle, Anne, Michael, Benedict, Reynolds, Will, Spencer, Lisa, Vinson, Ben, Ashworth, M, Abel, Kathryn, Chinoy, H, Deakin, Bill, Harvie, M, Miller, C A, Stanel, Stefan, Barran, Perdita, Trivedi, Drupad, McAllister-Williams, Hamish, Paddick, Stella-Maria, Rostron, Anthony, Taylor, John Paul, Baguley, David, Coleman, Chris, Cox, E, Fabbri, Laura, Francis, Susan, Hall, Ian, Hufton, E, Johnson, Simon, Khan, Fasih, Kitterick, Paaig, Morriss, Richard, Selby, Nick, Wright, Louise, Antoniades, Charalambos, Bates, A, Beggs, M, Bhui, Kamaldeep, Breeze, Katie, Channon, K M, Clark, David, Fu, X, Husain, Masud, Li, X, Lukaschuk, E, McCracken, Celeste, McGlynn, K, Menke, R, Motohashi, K, Nichols, T E, Ogbole, Godwin, Piechnik, S, Propescu, I, Propescu, J, Samat, A A, Sanders, Z B, Sigfrid, Louise, Webster, M, Kingham, Lucy, Klenerman, Paul, Lamlum, Hanan, Taquet, Maxime, Carson, G, Finnigan, L, Saunders, Laura, Wild, James, Calder, P C, Huneke, Nathan, Simons, Gemma, Baldwin, David, Bain, Steve, Daines, Luke, Bright, E, Crisp, P, Dharmagunawardena, Ruvini, Stern, M, Bailey, Elisabeth, Reddington, Anne, Wight, Andrew, Ashish, A, Cooper, Josh, Robinson, Emma, Broadley, Andrew, Barman, Laura, Brookes, Claire, Elliott, K, Griffiths, L, Guy, Zoe, Howard, Kate, Ionita, Diana, Redfearn, Heidi, Sarginson, Carol, Turnbull, Alison, Skorniewska, Zuzanna, De Deyn, Thomas, Hampshire, Adam, Trender, William R, Hellyer, Peter J, Chalmers, James D, Ho, Ling-Pei, Leavy, Olivia C, Richardson, Matthew, McAuley, Hamish J C, Singapuri, Amisha, Saunders, Ruth M, Harris, Victoria C, Greening, Neil J, Mansoori, Parisa, Harrison, Ewen M, Docherty, Annemarie B, Lone, Nazir I, Quint, Jennifer, Brightling, Christopher E, Wain, Louise V, Evans, Rachael A, Geddes, John R, and Harrison, Paul J
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- 2024
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45. Heart failure patients without echocardiography are more commonly diagnosed in hospital care and are associated with higher mortality compared to primary care
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Viktor Samskog, Jason Davidge, Anders Halling, and Björn Agvall
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Heart failure ,diagnostics ,one-year mortality ,primary care ,Public aspects of medicine ,RA1-1270 - Abstract
AbstractObjective This Swedish study aimed to assess the prevalence, associated clinical factors, and mortality rates of heart failure patients diagnosed without echocardiograms in both hospital and primary care settings.Design We conducted a retrospective population-based study using data from the Region Halland healthcare database in Sweden covering 330,000 residents.Subjects From 2013–2019, 3,903 patients received an incidental heart failure diagnosis without an echocardiogram and they were followed for one year.Main outcome measures Using logistic and Cox regression analyses, we evaluated the prevalence, clinical characteristics, and all-cause mortality at intervals of 30, 100, and 365 days post-diagnosis.Results In this Swedish cohort, the one-year all-cause mortality rate was markedly higher for patients diagnosed in hospitals (42%) compared to those in primary care (20%, p
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- 2024
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46. Meconium aspiration syndrome: a comprehensive review
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Osman, Ahmed, Halling, Cecilie, Crume, Mary, Al Tabosh, Hayat, Odackal, Namrita, and Ball, Molly K.
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- 2023
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47. History of urodynamics. Its origins, development and implication for urology as a specialty in Europe and the USA
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Moll, Friedrich H., Halling, Thorsten, and Schäfer, Werner
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- 2024
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48. Safety and sustainability by design: An explorative survey on concepts’ knowledge and application
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Leso, Veruscka, Rydberg, Tomas, Halling, Maja, Karakitsios, Spyros, Nikiforou, Fotini, Karakoltzidis, Achilleas, Sarigiannis, Denis A., and Iavicoli, Ivo
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- 2024
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49. 6 Principles to Foster Voice and Belonging. Online Exclusive
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Encarnación, Paola Deliz Félix, Halling, Mary, Carter, Andrea, and Wu, Stephanie
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Amid soaring rates of teacher burnout and attrition, those at City Year are finding a trend that may seem surprising: Participants in their Network for School Improvement, when asked how likely they would be to recommend the network to other colleagues, have given an average rating of 9 out of 10. The authors have found that six key principles can foster voice and belonging for educators so that educators, in turn, replicate those practices in classrooms with students. Here the authors describe those principles and give examples of how they model them for educators and how educators have implemented them with students. Those principles are: (1) Co-authored content and programming; (2) Space for powerful reflection; (3) Timely and relevant information; (4) Quick feedback loops; (5) Foster belonging through surprise and delight; and (6) Direct lines of communication. Educators can leverage the six principles presented here and implement them in ways that are appropriate to their contexts to make change. The results demonstrate the power of a network and collective knowledge and action. When teachers and principals feel appreciated, empowered, and valued, they are more likely to cultivate those same experiences and feelings in their students.
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- 2023
50. Do investors benefit from MiFID II unbundling?
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Fröberg, Emelie and Halling, Michael
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- 2024
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