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Aims: There is substantial evidence considering oxidative stress as one of the migraine pathogeneses. It seems higher dietary antioxidant intake could modulate migraine symptoms in sufferers. Therefore, we assessed the relationship between the dietary total antioxidant capacity (TAC) and migraine attack frequency. Method: 289 volunteer women with migraine were recruited. The usual participants' dietary intakes were collected using a validated food frequency questionnaire. The dietary total antioxidant capacity of women was determined via three different indices including dTAC, DAI, and DAQs. dTAC was calculated based on the USDA oxygen radical absorbance capacity (ORAC) database. The dietary intakes of vitamins A, E, C, selenium, zinc, and manganese were applied for calculating the DAI (Dietary Antioxidant Index) and DAQs (Dietary Antioxidant Quality score). The multivariate-adjusted ordinal regression was used to assess the relation of three indices scores with migraine attack frequency. Results: a lower score of dTAC was associated with a higher attack frequency [OR (95%CI) model3= 1.97(1.1–3.54), P-value= 0.02]. The women with DAQs= 1 and 3 had significantly higher migraine attack frequency compared to women with DAQs = 5 [DAQs = 1: OR (95%CI) model 3= 8.59 (1.06- 69.72), P-value = 0.04] and [DAQs = 3: OR (95%CI) model 3= 2.09 (1.13- 3.85), P-value= 0.02]. Moreover, the trend of changes among the DAQs and dTAC levels was significant (P-values for trend < 0.05). There was no significant association between tertiles of DAI and migraine attack frequency (P-value> 0.05). Conclusion: A high-quality diet in terms of antioxidant capacity is related to lower attack frequency in migrainous women. [ABSTRACT FROM AUTHOR]

Background: Migraine is a debilitating neurological discomfort characterized by moderate to severe unilateral headaches. Adherence to healthy dietary patterns like the DASH diet has been considered a complementary solution to migraine management. Objective: In this study, we assessed the relation of adherence to the DASH diet with migraine attack frequency and pain intensity in women with migraine. Methods: 285 female women with migraine were recruited in the current study. Migraine was diagnosed by a single neurologist based on the third edition of the International Classification of Headache Disorders (ICHD-III). Migraine attack frequency was determined based on the number of attacks per month. Pain intensity was assessed by the Visual Analogue Scale (VAS) and migraine index. Last year dietary intakes of women were collected using a semiquantitative food frequency questionnaire (FFQ). Results: Almost 91% of the women had migraine without aura. Most of the participants reported more than 15 attacks per month (40.7%) and pain intensity in the range of 8-10 in every attack (55.4%). Based on the ordinal regression, those in the first tertile of the DASH score had significantly higher odds for attack frequency (OR = 1.88; 95% CI: 1.11-3.18; P = .02) and migraine index score (OR = 1.69; 95% CI: 1.02-2.79; P = .04, respectively) than those in the third tertile. Conclusion: This study showed that a higher DASH score is associated with a lower migraine attack frequency and migraine index score in female sufferers. [ABSTRACT FROM AUTHOR]

Objectives: Migraine is a debilitating neurovascular disorder. The relation of diets and migraine is a controversial topic yet. This study assessed the association of dietary patterns of migrainous women with attack frequency. Methods: In this cross sectional study 285 volunteer migrainous women (25–55 years old) based on the third edition of International Classification of Headache Disorders (ICHD-3) recruited from neurology clinics of Golestan Hospital in Ahwaz, Iran. For collecting the data, the patients were interviewed. Dietary patterns of participants were assessed using a validated semi quantitative food frequency questionnaire which included 168 food items. Extraction of dietary patterns was performed using factor analysis. The association between dietary patterns and migraine attack frequency was analyzed by ordinal regression. Results: Two major dietary patterns which were extracted include the "western" and the "healthy" patterns. After adjustment for confounders, subjects with high adherence to healthy pattern had lower attack frequency (OR: 1.09; 95% CI: [0.51–2.25]; P for trend = 0.04); whereas, subjects with high adherence to western pattern had more attack frequency (OR: 0.89; 95% CI: [0.42–1.88]; P for trend = 0.02) significantly. Conclusions: Based on the results, adherence to healthy dietary pattern in migrainous women may be effective in controlling migraine attacks. [ABSTRACT FROM AUTHOR]