Search

Your search keyword '"Hagan, Jose"' showing total 37 results
Start Over Author "Hagan, Jose"
37 results on '"Hagan, Jose"'

1. Estimated number of lives directly saved by COVID-19 vaccination programmes in the WHO European Region from December, 2020, to March, 2023: a retrospective surveillance study

Author

Mesle, Margaux MI, Brown, Jeremy, Mook, Piers, Katz, Mark A, Hagan, Jose, Pastore, Roberta, Benka, Bernhard, Redlberger-Fritz, Monika, Bossuyt, Nathalie, Stouten, Veerle, Vernemmen, Catharina, Constantinou, Elisabet, Kynčl, Jan, Maly, Marek, Sanca, Ondrej, Krause, Tyra Grove, Vestergaard, Lasse Skafte, Leino, Tuija, Poukka, Eero, Gkolfinopoulou, Kassiani, Mellou, Kassiani, Tsintziloni, Maria, Molnár, Zsuzsanna, Aspelund, Gudrun, Thordardottir, Marianna, Domegan, Lisa, Kelly, Eva, O'Donell, Joan, Sacco, Chiara, Riccardo, Flavia, Urdiales, Alberto Mateo, Bumšteinas, Viktoras, Liausediene, Rasa, Mossong, Joël, Vergison, Anne, Borg, Maria-Louise, Melillo, Tanya, Kocinski, Dragan, Pollozhani, Enkela, Meijerink, Hinta, Costa, Diana, Gomes, João Paulo, Leite, Pedro Pinto, Druc, Alina, Gutu, Veaceslav, Mita, Valentin, Lazar, Mihaela, Popescu, Rodica, Popovici, Odette, Musilová, Monika, Mrzel, Maja, Socan, Maja, Učakar, Veronika, Limia, Aurora, Mazagatos, Clara, Olmedo, Carmen, Dabrera, Gavin, Kall, Meaghan, Sinnathamby, Mary, McMenamin, Jim, McGowan, Graham, Morrison, Kirsty, Nitzan, Dorit, Widdowson, Marc-Alain, Smallwood, Catherine, Pebody, Richard, Meslé, Margaux M I, Hagan, José, O’Donell, Joan, and Urdiales, Alberto-Mateo

Published
2024
Full Text
View/download PDF

2. Sustained detection of type 2 poliovirus in London sewage between February and July, 2022, by enhanced environmental surveillance

Author

Klapsa, Dimitra, Wilton, Thomas, Zealand, Andrew, Bujaki, Erika, Saxentoff, Eugene, Troman, Catherine, Shaw, Alexander G, Tedcastle, Alison, Majumdar, Manasi, Mate, Ryan, Akello, Joyce O, Huseynov, Shahin, Zeb, Ali, Zambon, Maria, Bell, Anita, Hagan, José, Wade, Matthew J, Ramsay, Mary, Grassly, Nicholas C, Saliba, Vanessa, and Martin, Javier

Published
2022
Full Text
View/download PDF

5. Progress towards rubella elimination--Western Pacific Region, 2000-2019/Progres vers l'elimination de la rubeole, Region du Pacifique occidental, 2000-2019

Author

Knapp, Jennifer K., Mariano, Kayla M., Pastore, Roberta, Grabovac, Varja, Takashima, Yoshihiro, Alexander, James P., Jr., Reef, Susan E., and Hagan, Jose E.

Subjects
Vaccines, Disease eradication, Birth defects, Rubella, Genetic disorders, Government, Health, United Nations. Children's Fund
Abstract

Rubella is the leading vaccine-preventable cause of birth defects. Whereas rubella typically manifests as a mild febrile rash illness, infection during pregnancy, particularly during the first trimester, can result in [...]

Published
2020

6. Influence of Rainfall on Leptospira Infection and Disease in a Tropical Urban Setting, Brazil

Author

Hacker, Kathryn P., Sacramento, Gielson A., Cruz, Jaqueline S., de Oliveira, Daiana, Nery, Nivison, Jr., Lindow, Janet C., Carvalho, Mayara, Hagan, Jose, Diggle, Peter J., Begon, Mike, Reis, Mitermayer G., Wunder, Elsio A., Jr., Ko, Albert I., and Costa, Federico

Subjects
Rain -- Health aspects, Gram-negative bacteria -- Health aspects, Death, Floods, Extreme weather, Global strategy (Marketing), Sewer systems, Hemorrhage, Health, Diseases, Urban poor, Leptospirosis, Storm damage, Setting (Literature), Urban population, Hurricanes, Health
Abstract

Leptospirosis, a leading zoonotic cause of illness and death (1), has emerged as a major health problem due to the global expansion of urban slum communities (2-4). The disease is [...]

Published
2020
Full Text
View/download PDF

11. Anicteric Leptospirosis-Associated Meningitis in a Tropical Urban Environment, Brazil

Author

Nabity, Scott A., Araujo, Guilherme C., Hagan, Jose E., Damiao, Alcineia O., Reis, Mitermayer G., Ko, Albert I., and Ribeiro, Guilherme S.

Subjects
Leptospirosis -- Health aspects, Meningitis -- Health aspects, Type 2 diabetes -- Health aspects, Health
Abstract

The clinical signs of leptospirosis can vary widely, which complicates timely diagnosis and targeted therapy. Aseptic meningitis associated with Leptospira infection, hereafter termed leptospirosis-associated meningitis (LAM), has been well described [...]

Published
2020
Full Text
View/download PDF

12. Progress towards measles elimination, Western Pacific Region, 2013-2017/Progres vers l'elimination de la rougeole, Region du Pacifique occidental, 2013-2017

Author

Hagan, Jose E., Kriss, Jennifer L., Takashima, Yoshihiro, Mariano, Kayla Mae L., Pastore, Roberta, Grabovac, Varja, Dabbagh, Alya J., and Goodson, James L.

Subjects
Measles -- Care and treatment -- Control -- Research, Sentinel surveillance -- Research, Government, Health
Abstract

In 2005, the Regional Committee of the WHO Western Pacific Region (WPR) (1) established a goal for eliminating measles (2) by 2012. (3) To achieve this goal, the 37 countries [...]

Published
2018

13. Multistate Outbreak of Respiratory Infections Among Unaccompanied Children, June 2014–July 2014

Author

Tomczyk, Sara, Arriola, Carmen S., Beall, Bernard, Benitez, Alvaro, Benoit, Stephen R., Berman, LaShondra, Bresee, Joseph, Carvalho, Maria da Gloria, Cohn, Amanda, Cross, Kristen, Diaz, Maureen H., Watkins, Louise K. Francois, Gierke, Ryan, Hagan, Jose E., Harris, Aaron M., Jain, Seema, Kim, Lindsay, Kobayashi, Miwako, Lindstrom, Stephen, McGee, Lesley, McMorrow, Meredith, Metcalf, Benjamin L., Moore, Matthew R., Moura, Iaci, Nix, W. Allan, Nyangoma, Edith, Oberste, M. Steven, Olsen, Sonja J., Pimenta, Fabiana, Socias, Christina, Thurman, Kathleen, Waller, Jessica, Waterman, Stephen H., Westercamp, Matthew, Wharton, Melinda, Whitney, Cynthia G., Winchell, Jonas M., Wolff, Bernard, and Kim, Curi

Published
2016

15. Rapid Response to Ebola Outbreaks in Remote Areas — Liberia, July–November 2014

Author

Kateh, Francis, Nagbe, Thomas, Kieta, Abraham, Barskey, Albert, Gasasira, Alex Ntale, Driscoll, Anne, Tucker, Anthony, Christie, Athalia, Karmo, Ben, Scott, Colleen, Bowah, Collin, Barradas, Danielle, Blackley, David, Dweh, Emmanuel, Warren, Felicia, Mahoney, Frank, Kassay, Gabriel, Calvert, Geoffrey M., Castro, Georgina, Logan, Gorbee, Appiah, Grace, Kirking, Hannah, Koon, Hawa, Papowitz, Heather, Walke, Henry, Cole, Isaac B., Montgomery, Joel, Neatherlin, John, Tappero, Jordan W., Hagan, Jose E., Forrester, Joseph, Woodring, Joseph, Mott, Joshua, Attfield, Kathleen, DeCock, Kevin, Lindblade, Kim A., Powell, Krista, Yeoman, Kristin, Adams, Laura, Broyles, Laura N., Slutsker, Laurence, Larway, Lawrence, Belcher, Lisa, Cooper, Lorraine, Santos, Marjorie, Westercamp, Matthew, Weinberg, Meghan Pearce, Massoudi, Mehran, Dea, Monica, Patel, Monita, Hennessey, Morgan, Fomba, Moses, Lubogo, Mutaawe, Maxwell, Nikki, Moonan, Patrick, Arzoaquoi, Sampson, Gee, Samuel, Zayzay, Samuel, Pillai, Satish, Williams, Seymour, Zarecki, Shauna Mettee, Yett, Sheldon, James, Stephen, Grube, Steven, Gupta, Sundeep, Nelson, Thelma, Malibiche, Theophil, Frank, Wilmont, Smith, Wilmot, and Nyenswah, Tolbert

Published
2015

18. Linking rattiness, geography and environmental degradation to spillover Leptospira infections in marginalised urban settings:an eco-epidemiological community-based cohort study in Brazil

Author

Eyre, Max, Souza, Fábio N, Carvalho-Pereira, Ticiana, Nery Jr., Nivison, de Oliveira, Daiana, Cruz, Jaqueline S., Sacramento, Gielson A., Khalil, Hussein, Wunder Jr., Elsio A., Hacker, Kathryn P., Hagan, Jose E., Childs, James E., Reis, Mitermayer G., Begon, Mike, Diggle, Peter, Ko, Albert I., Giorgi, Emanuele, Costa, Federico, Eyre, Max, Souza, Fábio N, Carvalho-Pereira, Ticiana, Nery Jr., Nivison, de Oliveira, Daiana, Cruz, Jaqueline S., Sacramento, Gielson A., Khalil, Hussein, Wunder Jr., Elsio A., Hacker, Kathryn P., Hagan, Jose E., Childs, James E., Reis, Mitermayer G., Begon, Mike, Diggle, Peter, Ko, Albert I., Giorgi, Emanuele, and Costa, Federico

Published
2022

19. Decreased Ebola transmission after rapid response to outbreaks in remote areas, Liberia, 2014

Author

Lindblade, Kim A., Kateh, Francis, Nagbe, Thomas K., Neatherlin, John C., Pillai, Satish K., Attfield, Kathleen R., Dweh, Emmanuel, Barradas, Danielle T., Williams, Seymour G., Blackley, David J., Kirking, Hannah L., Patel, Monita R., Dea, Monica, Massoudi, Mehran S., Wannemuehler, Kathleen, Barskey, Albert E., Zarecki, Shauna L. Mettee, Fomba, Moses, Grube, Steven, Belcher, Lisa, Broyles, Laura N., Maxwell, T. Nikki, Hagan, Jose E., Yeoman, Kristin, Westercamp, Matthew, Forrester, Joseph, Mott, Joshua, Mahoney, Frank, Slutsker, Laurence, DeCock, Kevin M., and Nyenswah, Tolbert

Subjects
Ebola virus infections -- Health aspects -- Risk factors -- Research, Disease transmission -- Research, Health
Abstract

The current Ebola virus disease (Ebola) epidemic in West Africa, caused by the Zaire strain, is the largest in history; >27,000 cases have been reported since Ebola was detected in [...]

Published
2015
Full Text
View/download PDF

20. Progress towards polio eradication worldwide, 2014-2015/Progres accomplis en vue de l'eradication de la poliomyelite a l'echelle mondiale, 2014-2015

Author

Hagan, Jose E., Wassilak, Steven G.F., Craig, Allen S., Tangermann, Rudolf H., Diop, Ousmane M., Burns, Cara C., and Quddus, Arshad

Subjects
Poliomyelitis -- Prevention -- Research, Poliovirus vaccines -- Health aspects -- Research, Government, Health
Abstract

In 1988, the World Health Assembly (WHA) resolved to eradicate polio worldwide. Since then, endemic transmission of wild poliovirus (WPV) has been interrupted in all countries except Afghanistan, Nigeria and [...]

Published
2015

22. Secondary infections with Ebola virus in rural communities, Liberia and guinea, 2014-2015

Author

Lindblade, Kim A., Nyenswah, Tolbert, Keita, Sakoba, Diallo, Boubakar, Kateh, Francis, Amoah, Aurora, Nagbe, Thomas K., Raghunathan, Pratima, Neatherlin, John C., Kinzer, Mike, Pillai, Satish K., Attfield, Kathleen R., Hajjeh, Rana, Dweh, Emmanuel, Painter, John, Barradas, Danielle T., Williams, Seymour G., Blackley, David J., Kirking, Hannah L., Patel, Monita R., Dea, Monica, Massoudi, Mehran S., Barskey, Albert E., Zarecki, Shauna L. Mettee, Fomba, Moses, Grube, Steven, Belcher, Lisa, Broyles, Laura N., Maxwell, T. Nikki, Hagan, Jose E., Yeoman, Kristin, Westercamp, Matthew, Mott, Joshua, Mahoney, Frank, Slutsker, Laurence, DeCock, Kevin M., Marston, Barbara, and Dahl, Benjamin

Subjects
United States. Centers for Disease Control and Prevention, Ebola hemorrhagic fever -- Development and progression -- Prevention -- Health aspects, Disease transmission -- Development and progression -- Prevention -- Health aspects, Ebola virus -- Health aspects, Health, World Health Organization
Abstract

Transmission of Ebola virus occurs through direct contact with blood or other body fluids of an infected person after symptoms have developed. During an outbreak of Ebola virus disease (EVD), [...]

Published
2016
Full Text
View/download PDF

25. Increase in Infant Measles Deaths During a Nationwide Measles Outbreak—Mongolia, 2015–2016

Author

Lee, Christopher T, primary, Hagan, Jose E, additional, Jantsansengee, Baigalmaa, additional, Tumurbaatar, Oyun-Erdene, additional, Altanchimeg, Samdan, additional, Yadamsuren, Buyanjargal, additional, Demberelsuren, Sodbayar, additional, Tserendorj, Chinbayar, additional, Munkhtogoo, Oyungerel, additional, Badarch, Darmaa, additional, Gunregjav, Nyamaa, additional, Baatarkhuu, Bolortuya, additional, Ochir, Chimedsuren, additional, Berman, LaShondra, additional, Anderson, Raydel, additional, Patel, Minal K, additional, Gregory, Christopher J, additional, and Goodson, James L, additional

Published
2019
Full Text
View/download PDF

26. Correction: Cathelicidin Insufficiency in Patients with Fatal Leptospirosis

Author

Lindow, Janet C., primary, Wunder, Elsio A., additional, Popper, Stephen J., additional, Min, Jin-na, additional, Mannam, Praveen, additional, Srivastava, Anup, additional, Yao, Yi, additional, Hacker, Kathryn P., additional, Raddassi, Khadir, additional, Lee, Patty J., additional, Montgomery, Ruth R., additional, Shaw, Albert C., additional, Hagan, Jose E., additional, Araújo, Guilherme C., additional, Nery, Nivison, additional, Relman, David A., additional, Kim, Charles C., additional, Reis, Mitermayer G., additional, and Ko, Albert I., additional

Published
2017
Full Text
View/download PDF

27. Spatiotemporal determinants of urban leptospirosis transmission: Four-year prospective cohort study of slum residents in Brazil

Author

Hagan, Jose, Moraga Serrano, Paula Esther, Costa, Federico, Capian, Nicolas, Ribeiro, Guilherme, Wunder, Jr., Elsio, Felzemburgh, Ridalva, Reis, Renato, Nery, Nivison, Santana, Francisco, other, and, Hagan, Jose, Moraga Serrano, Paula Esther, Costa, Federico, Capian, Nicolas, Ribeiro, Guilherme, Wunder, Jr., Elsio, Felzemburgh, Ridalva, Reis, Renato, Nery, Nivison, Santana, Francisco, and other, and

Abstract

Background Rat-borne leptospirosis is an emerging zoonotic disease in urban slum settlements for which there are no adequate control measures. The challenge in elucidating risk factors and informing approaches for prevention is the complex and heterogeneous environment within slums, which vary at fine spatial scales and influence transmission of the bacterial agent. Methodology/Principal Findings We performed a prospective study of 2,003 slum residents in the city of Salvador, Brazil during a four-year period (2003–2007) and used a spatiotemporal modelling approach to delineate the dynamics of leptospiral transmission. Household interviews and Geographical Information System surveys were performed annually to evaluate risk exposures and environmental transmission sources. We completed annual serosurveys to ascertain leptospiral infection based on serological evidence. Among the 1,730 (86%) individuals who completed at least one year of follow-up, the infection rate was 35.4 (95% CI, 30.7–40.6) per 1,000 annual follow-up events. Male gender, illiteracy, and age were independently associated with infection risk. Environmental risk factors included rat infestation (OR 1.46, 95% CI, 1.00–2.16), contact with mud (OR 1.57, 95% CI 1.17–2.17) and lower household elevation (OR 0.92 per 10m increase in elevation, 95% CI 0.82–1.04). The spatial distribution of infection risk was highly heterogeneous and varied across small scales. Fixed effects in the spatiotemporal model accounted for the majority of the spatial variation in risk, but there was a significant residual component that was best explained by the spatial random effect. Although infection risk varied between years, the spatial distribution of risk associated with fixed and random effects did not vary temporally. Specific “hot-spots” consistently had higher transmission risk during study years. Conclusions/Significance The risk for leptospiral infection in urban slums is determined in large part by structural feature

Published
2016

28. Spatiotemporal determinants of urban Leptospirosis transmission:four-year prospective cohort study of slum residents in Brazil

Author

Hagan, Jose E., Moraga-Serrano, Paula Esther, Costa, Federico, Capian, Nicolas, Ribeiro, Guilherme S., Wunder, Elsio A., Felzemburgh, Ridalva D. M., Reis, Renato B., Nery, Nivison, Santana, Francisco S., Fraga, Deborah, dos Santos, Balbino L., Santos, Andrei c., Queiroz, Adriano, Tassinari, Wagner, Sa Carvalho, Marilia, Reis, Mitermayer G., Diggle, Peter John, Ko, Albert I., Hagan, Jose E., Moraga-Serrano, Paula Esther, Costa, Federico, Capian, Nicolas, Ribeiro, Guilherme S., Wunder, Elsio A., Felzemburgh, Ridalva D. M., Reis, Renato B., Nery, Nivison, Santana, Francisco S., Fraga, Deborah, dos Santos, Balbino L., Santos, Andrei c., Queiroz, Adriano, Tassinari, Wagner, Sa Carvalho, Marilia, Reis, Mitermayer G., Diggle, Peter John, and Ko, Albert I.

Abstract

Background Rat-borne leptospirosis is an emerging zoonotic disease in urban slum settlements for which there are no adequate control measures. The challenge in elucidating risk factors and informing approaches for prevention is the complex and heterogeneous environment within slums, which vary at fine spatial scales and influence transmission of the bacterial agent. Methodology/Principal Findings We performed a prospective study of 2,003 slum residents in the city of Salvador, Brazil during a four-year period (2003–2007) and used a spatiotemporal modelling approach to delineate the dynamics of leptospiral transmission. Household interviews and Geographical Information System surveys were performed annually to evaluate risk exposures and environmental transmission sources. We completed annual serosurveys to ascertain leptospiral infection based on serological evidence. Among the 1,730 (86%) individuals who completed at least one year of follow-up, the infection rate was 35.4 (95% CI, 30.7–40.6) per 1,000 annual follow-up events. Male gender, illiteracy, and age were independently associated with infection risk. Environmental risk factors included rat infestation (OR 1.46, 95% CI, 1.00–2.16), contact with mud (OR 1.57, 95% CI 1.17–2.17) and lower household elevation (OR 0.92 per 10m increase in elevation, 95% CI 0.82–1.04). The spatial distribution of infection risk was highly heterogeneous and varied across small scales. Fixed effects in the spatiotemporal model accounted for the majority of the spatial variation in risk, but there was a significant residual component that was best explained by the spatial random effect. Although infection risk varied between years, the spatial distribution of risk associated with fixed and random effects did not vary temporally. Specific “hot-spots” consistently had higher transmission risk during study years. Conclusions/Significance The risk for leptospiral infection in urban slums is determined in large part by structural feature

Published
2016

29. Implementation of Ebola case-finding using a village chieftaincy taskforce in a remote outbreak--Liberia, 2014

Author

Hagan, Jose E., Smith, Wilmot, Pillai, Satish K., Yeoman, Kristin, Gupta, Sundeep, Neatherlin, John, Slutsker, Laurence, Lindblade, Kim A., DeCock, Kevin M., Kateh, Francis, and Nyenswah, Tolbert

Subjects
Task forces, Ebola virus infections, Virus diseases, Health
Abstract

On October 16, 2014, a woman aged 48 years traveled from Monrovia, Liberia, to the Kayah region of Rivercess County, a remote, resource-poor, and sparsely populated region of Liberia, and [...]

Published
2016

30. Cathelicidin Insufficiency in Patients with Fatal Leptospirosis

Author

Lindow, Janet C., primary, Wunder, Elsio A., additional, Popper, Stephen J., additional, Min, Jin-na, additional, Mannam, Praveen, additional, Srivastava, Anup, additional, Yao, Yi, additional, Hacker, Kathryn P., additional, Raddassi, Khadir, additional, Lee, Patty J., additional, Montgomery, Ruth R., additional, Shaw, Albert C., additional, Hagan, Jose E., additional, Araújo, Guilherme C., additional, Nery, Nivison, additional, Relman, David A., additional, Kim, Charles C., additional, Reis, Mitermayer G., additional, and Ko, Albert I., additional

Published
2016
Full Text
View/download PDF

31. Infant Feeding Practices were not Associated with Breast Milk HIV-1 RNA Levels in a Randomized Clinical Trial in Botswana

Author

Rossenkhan, Raabya, primary, Novitsky, Vladimir, additional, Sebunya, Teresa K., additional, Leidner, Jean, additional, Hagan, Jose E., additional, Moyo, Sikhulile, additional, Smeaton, Laura, additional, Lockman, Shahin, additional, Musonda, Rosemary, additional, Ndung’u, Thumbi, additional, Gaseitsiwe, Simani, additional, Thior, Ibou, additional, Mmalane, Mompati, additional, Makhema, Joseph, additional, Essex, M., additional, and Shapiro, Roger, additional

Published
2011
Full Text
View/download PDF

32. Temporal Reduction of HIV Type 1 Viral Load in Breast Milk by Single-Dose Nevirapine during Prevention of MTCT

Author

Rossenkhan, Raabya, primary, Ndung'u, Thumbi, additional, Sebunya, Teresa K., additional, Hagan, Jose E., additional, Shapiro, Roger, additional, Novitsky, Vladimir, additional, Moyo, Sikhulile M., additional, Thior, Ibou, additional, Lockman, Shahin, additional, Mitchell, Rebecca, additional, Kim, Soyeon, additional, Musonda, Rosemary, additional, van Widenfelt, Erik, additional, Makhema, Joseph, additional, and Essex, M., additional

Published
2009
Full Text
View/download PDF

36. Notes from the field: hospitalizations for respiratory disease among unaccompanied children from Central America - multiple States, June-July 2014.

Author

Nyangoma, Edith N, Arriola, Carmen Sofia, Hagan, Jose, Socias, Christina, Tomczyk, Sara, Watkins, Louise Francois, Westercamp, Matthew, Kim, Curi, Epidemic Intelligence Service, CDC, and Centers for Disease Control and Prevention

Abstract

During October 2013-June 2014, approximately 54,000 unaccompanied children, mostly from the Central American countries of El Salvador, Guatemala, and Honduras, were identified attempting entry into the United States from Mexico, exceeding numbers reported in previous years. Once identified in the United States, U.S. Customs and Border Protection, an agency of the U.S. Department of Homeland Security, processes the unaccompanied children and transfers them to the Office of Refugee Resettlement (ORR), an office of the Administration for Children and Families, U.S. Department of Health and Human Services. ORR cares for the children in shelters until they can be released to a sponsor, typically a parent or relative, who can care for the child while their immigration case is processed. In June 2014, in response to the increased number of unaccompanied children, U.S. Customs and Border Protection expanded operations to accommodate children at a processing center in Nogales, Arizona. ORR, together with the U.S. Department of Defense, opened additional large temporary shelters for the children at Lackland Air Force Base, Texas; U.S. Army Garrison Ft. Sill, Oklahoma; and Naval Base Ventura County, California. [ABSTRACT FROM AUTHOR]

Published
2014

37. Rapid response to Ebola outbreaks in remote areas - Liberia, July-November 2014.

Author

Kateh F, Nagbe T, Kieta A, Barskey A, Gasasira AN, Driscoll A, Tucker A, Christie A, Karmo B, Scott C, Bowah C, Barradas D, Blackley D, Dweh E, Warren F, Mahoney F, Kassay G, Calvert GM, Castro G, Logan G, Appiah G, Kirking H, Koon H, Papowitz H, Walke H, Cole IB, Montgomery J, Neatherlin J, Tappero JW, Hagan JE, Forrester J, Woodring J, Mott J, Attfield K, DeCock K, Lindblade KA, Powell K, Yeoman K, Adams L, Broyles LN, Slutsker L, Larway L, Belcher L, Cooper L, Santos M, Westercamp M, Weinberg MP, Massoudi M, Dea M, Patel M, Hennessey M, Fomba M, Lubogo M, Maxwell N, Moonan P, Arzoaquoi S, Gee S, Zayzay S, Pillai S, Williams S, Zarecki SM, Yett S, James S, Grube S, Gupta S, Nelson T, Malibiche T, Frank W, Smith W, and Nyenswah T

Subjects
Adolescent, Adult, Aged, Aged, 80 and over, Child, Child, Preschool, Disease Outbreaks statistics & numerical data, Female, Hemorrhagic Fever, Ebola epidemiology, Humans, Infant, Liberia epidemiology, Male, Middle Aged, Time Factors, Young Adult, Disease Outbreaks prevention & control, Ebolavirus isolation & purification, Hemorrhagic Fever, Ebola prevention & control, Rural Population statistics & numerical data
Abstract

West Africa is experiencing its first epidemic of Ebola virus disease (Ebola). As of February 9, Liberia has reported 8,864 Ebola cases, of which 3,147 were laboratory-confirmed. Beginning in August 2014, the Liberia Ministry of Health and Social Welfare (MOHSW), supported by CDC, the World Health Organization (WHO), and others, began systematically investigating and responding to Ebola outbreaks in remote areas. Because many of these areas lacked mobile telephone service, easy road access, and basic infrastructure, flexible and targeted interventions often were required. Development of a national strategy for the Rapid Isolation and Treatment of Ebola (RITE) began in early October. The strategy focuses on enhancing capacity of county health teams (CHT) to investigate outbreaks in remote areas and lead tailored responses through effective and efficient coordination of technical and operational assistance from the MOHSW central level and international partners. To measure improvements in response indicators and outcomes over time, data from investigations of 12 of 15 outbreaks in remote areas with illness onset dates of index cases during July 16-November 20, 2014, were analyzed. The times to initial outbreak alerts and durations of the outbreaks declined over that period while the proportions of patients who were isolated and treated increased. At the same time, the case-fatality rate in each outbreak declined. Implementation of strategies, such as RITE, to rapidly respond to rural outbreaks of Ebola through coordinated and tailored responses can successfully reduce transmission and improve outcomes.

Published
2015

Catalog

Books, media, physical & digital resources
See catalog results