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6 results on '"Hafner JP"'

1. A 51-Year-Old Man With a Large Posterior Mediastinal Mass.

Author

Chieng H, Hafner JP, Mccarthy L, Ibrahim A, Itty R, Chong WH, Saha B, and Conuel E

Subjects
Cough physiopathology, Cytoreduction Surgical Procedures, Decompression, Surgical, Disease Progression, Dyspnea physiopathology, Forced Expiratory Volume, Fractures, Compression diagnostic imaging, Fractures, Compression etiology, Fractures, Compression surgery, Hodgkin Disease complications, Hodgkin Disease pathology, Hodgkin Disease physiopathology, Humans, Male, Mediastinal Neoplasms complications, Mediastinal Neoplasms pathology, Mediastinal Neoplasms physiopathology, Mediastinitis complications, Mediastinitis drug therapy, Mediastinitis physiopathology, Middle Aged, Prednisone therapeutic use, Rituximab therapeutic use, Spinal Fractures diagnostic imaging, Spinal Fractures etiology, Spinal Fractures surgery, Thoracic Vertebrae diagnostic imaging, Thoracic Vertebrae surgery, Tomography, X-Ray Computed, Vital Capacity, Hodgkin Disease diagnosis, Mediastinal Neoplasms diagnosis, Mediastinitis diagnosis
Abstract

Case Presentation: A 51-year-old White male never-smoker presented with intermittent cough and progressive dyspnea. His symptoms started after an exposure to bat guano while cleaning his attic approximately 9 months earlier. He has received several courses of antibiotic and corticosteroid for these symptoms, with short-term relief., (Copyright © 2021 American College of Chest Physicians. All rights reserved.)

Published
2021
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2. The authors reply.

Author

McNutt LA, Wu C, Xue X, and Hafner JP

Subjects
Humans, Clinical Trials as Topic methods, Odds Ratio, Outcome Assessment, Health Care methods, Risk
Published
2014
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3. Staphylococcus lugdunensis endocarditis following lower extremity revascularization.

Author

Viganego F, Nazir TM, Lee CY, Hafner JP, and Smith R

Subjects
Aged, Aortic Valve microbiology, Endocarditis, Bacterial diagnosis, Endocarditis, Bacterial therapy, Fatal Outcome, Femoral Artery surgery, Heart Failure microbiology, Humans, Lower Extremity blood supply, Male, Popliteal Artery surgery, Reperfusion adverse effects, Staphylococcal Infections diagnosis, Staphylococcal Infections therapy, Staphylococcus isolation & purification, Arterial Occlusive Diseases surgery, Endocarditis, Bacterial microbiology, Lower Extremity surgery, Staphylococcal Infections microbiology, Vascular Surgical Procedures adverse effects
Abstract

We describe a fatal case of Staphylococcus lugdunensis aortic valve endocarditis that was diagnosed in a 75-year-old man approximately 6 months following a lower extremity by-pass surgery. A relatively indolent clinical course in the early phase following the suspicious exposure may have contributed to a delay in the diagnosis. At the time of presentation the patient had evidence of rapidly progressive congestive heart failure with anasarca, dyspnea and low grade fevers. Blood cultures were positive for coagulase-negative staphylococci and a transthoracic echocardiogram was not clearly suggestive of infective endocarditis. Despite intense medical treatment the patient expired on day four of hospitalization. On post-mortem examination, multiple vegetations were observed on the aortic valve and culture identification showed S. lugdunensis. Early detection of coagulase-negative bacteremia from multiple blood culture samples in this clinical setting is critical and should give rise to a suspicion of this rare but often fatal form of infective endocarditis. Besides appropriate antibiotic treatment, early surgical referral for valve replacement should be considered since it appears to be the only treatment positively affecting survival. Finally, further studies are needed to establish the efficacy of antibiotic prophylaxis in patients undergoing angiograms with a femoral approach.

Published
2007
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4. Estimating the relative risk in cohort studies and clinical trials of common outcomes.

Author

McNutt LA, Wu C, Xue X, and Hafner JP

Subjects
Cohort Studies, Cross-Sectional Studies, Data Interpretation, Statistical, Health Services Research methods, Humans, Poisson Distribution, Clinical Trials as Topic methods, Odds Ratio, Outcome Assessment, Health Care methods, Risk
Abstract

Logistic regression yields an adjusted odds ratio that approximates the adjusted relative risk when disease incidence is rare (<10%), while adjusting for potential confounders. For more common outcomes, the odds ratio always overstates the relative risk, sometimes dramatically. The purpose of this paper is to discuss the incorrect application of a proposed method to estimate an adjusted relative risk from an adjusted odds ratio, which has quickly gained popularity in medical and public health research, and to describe alternative statistical methods for estimating an adjusted relative risk when the outcome is common. Hypothetical data are used to illustrate statistical methods with readily accessible computer software.

Published
2003
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5. Predictors of mortality for patients undergoing cardiac valve replacements in New York State.

Author

Hannan EL, Racz MJ, Jones RH, Gold JP, Ryan TJ, Hafner JP, and Isom OW

Subjects
Aged, Aged, 80 and over, Combined Modality Therapy, Coronary Artery Bypass, Databases, Factual, Female, Heart Valve Diseases mortality, Humans, Male, Middle Aged, New York, Risk Assessment, Survival Rate, Cause of Death, Heart Valve Diseases surgery, Heart Valve Prosthesis Implantation, Postoperative Complications mortality
Abstract

Background: The objective of this study was to identify the mortality rates and significant independent risk factors for mortality for each of six valve replacement groups., Methods: A total of 14,190 patients who underwent valve replacement in New York State from 1995 to 1997 were classified into six major groups and significant independent risk factors for inpatient mortality were identified for each of the groups using stepwise logistic regression., Results: Mortality rates ranged from 3.33% for isolated aortic valve surgical procedures to 18.72% for multiple valve replacements with coronary artery bypass graft operations. The number of years in excess of age 55 was a significant multivariate predictor of mortality for all six groups of patients. Shock was a significant predictor for five of the six groups, and in each of those groups it was the risk factor with the highest odds ratio., Conclusions: Significant patient risk factors are relatively consistent across different types of valve replacement procedures. The probability of survival from valve surgical procedures is highly dependent on the patient's preoperative profile and the type of valve operation.

Published
2000
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