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1. Validation in the general population of a C-peptide estimate equation to measure beta cell function in recent-onset type 1 diabetes.

Author

Wang, Joanna, Bediaga, Naiara, Mallone, Roberto, Larger, Etienne, Harrison, Leonard C., Wentworth, John M., the ImMaDiab Study Group, Carel, Jean-Claude, Tubiana-Rufi, Nadia, Martinerie, Laetitia, Poidvin, Amélie, Jacqz-Aigrain, Evelyne, Corvez, Laurence, Berruer, Véronique, Gautier, Jean-François, Baz, Baz, Haddadi, Nassima, Andreelli, Fabrizio, Amouyal, Chloé, and Jaqueminet, Sophie

Subjects
TYPE 1 diabetes, PANCREATIC beta cells, BETA functions, CELL physiology, C-peptide, AUTOANTIBODIES
Abstract

Beta cell function, measured as the average C-peptide response to a mixed meal (CP SB AVE sb ), is commonly used to assess the effectiveness of immune therapy in recent-onset type 1 diabetes. A similar pattern for CP SB EST sb was also observed, although CP SB EST sb was significantly higher than CP SB AVE sb at 3, 6 and 12 months. [Extracted from the article]

Published
2021
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