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1. Integrated longitudinal multiomics study identifies immune programs associated with acute COVID-19 severity and mortality

Author

Gygi, Jeremy P, Maguire, Cole, Patel, Ravi K, Shinde, Pramod, Konstorum, Anna, Shannon, Casey P, Xu, Leqi, Hoch, Annmarie, Jayavelu, Naresh Doni, Haddad, Elias K, Network, IMPACC, Reed, Elaine F, Kraft, Monica, McComsey, Grace A, Metcalf, Jordan P, Ozonoff, Al, Esserman, Denise, Cairns, Charles B, Rouphael, Nadine, Bosinger, Steven E, Kim-Schulze, Seunghee, Krammer, Florian, Rosen, Lindsey B, van Bakel, Harm, Wilson, Michael, Eckalbar, Walter L, Maecker, Holden T, Langelier, Charles R, Steen, Hanno, Altman, Matthew C, Montgomery, Ruth R, Levy, Ofer, Melamed, Esther, Pulendran, Bali, Diray-Arce, Joann, Smolen, Kinga K, Fragiadakis, Gabriela K, Becker, Patrice M, Sekaly, Rafick P, Ehrlich, Lauren IR, Fourati, Slim, Peters, Bjoern, Kleinstein, Steven H, and Guan, Leying

Subjects
Biomedical and Clinical Sciences, Immunology, Clinical Research, Rare Diseases, 2.1 Biological and endogenous factors, Aetiology, Good Health and Well Being, Humans, COVID-19, Male, Longitudinal Studies, SARS-CoV-2, Female, Middle Aged, Severity of Illness Index, Aged, Adult, Cytokines, Multiomics, IMPACC Network, Adaptive immunity, Innate immunity, Medical and Health Sciences, Biological sciences, Biomedical and clinical sciences, Health sciences
Abstract

BACKGROUNDPatients hospitalized for COVID-19 exhibit diverse clinical outcomes, with outcomes for some individuals diverging over time even though their initial disease severity appears similar to that of other patients. A systematic evaluation of molecular and cellular profiles over the full disease course can link immune programs and their coordination with progression heterogeneity.METHODSWe performed deep immunophenotyping and conducted longitudinal multiomics modeling, integrating 10 assays for 1,152 Immunophenotyping Assessment in a COVID-19 Cohort (IMPACC) study participants and identifying several immune cascades that were significant drivers of differential clinical outcomes.RESULTSIncreasing disease severity was driven by a temporal pattern that began with the early upregulation of immunosuppressive metabolites and then elevated levels of inflammatory cytokines, signatures of coagulation, formation of neutrophil extracellular traps, and T cell functional dysregulation. A second immune cascade, predictive of 28-day mortality among critically ill patients, was characterized by reduced total plasma Igs and B cells and dysregulated IFN responsiveness. We demonstrated that the balance disruption between IFN-stimulated genes and IFN inhibitors is a crucial biomarker of COVID-19 mortality, potentially contributing to failure of viral clearance in patients with fatal illness.CONCLUSIONOur longitudinal multiomics profiling study revealed temporal coordination across diverse omics that potentially explain the disease progression, providing insights that can inform the targeted development of therapies for patients hospitalized with COVID-19, especially those who are critically ill.TRIAL REGISTRATIONClinicalTrials.gov NCT04378777.FUNDINGNIH (5R01AI135803-03, 5U19AI118608-04, 5U19AI128910-04, 4U19AI090023-11, 4U19AI118610-06, R01AI145835-01A1S1, 5U19AI062629-17, 5U19AI057229-17, 5U19AI125357-05, 5U19AI128913-03, 3U19AI077439-13, 5U54AI142766-03, 5R01AI104870-07, 3U19AI089992-09, 3U19AI128913-03, and 5T32DA018926-18); NIAID, NIH (3U19AI1289130, U19AI128913-04S1, and R01AI122220); and National Science Foundation (DMS2310836).

Published
2024

2. IgM N-glycosylation correlates with COVID-19 severity and rate of complement deposition

Author

Haslund-Gourley, Benjamin S., Woloszczuk, Kyra, Hou, Jintong, Connors, Jennifer, Cusimano, Gina, Bell, Mathew, Taramangalam, Bhavani, Fourati, Slim, Mege, Nathan, Bernui, Mariana, Altman, Matthew C., Krammer, Florian, van Bakel, Harm, Maecker, Holden T., Rouphael, Nadine, Diray-Arce, Joann, Wigdahl, Brian, Kutzler, Michele A., Cairns, Charles B., Haddad, Elias K., and Comunale, Mary Ann

Published
2024
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3. Features of acute COVID-19 associated with post-acute sequelae of SARS-CoV-2 phenotypes: results from the IMPACC study

Author

Ozonoff, Al, Jayavelu, Naresh Doni, Liu, Shanshan, Melamed, Esther, Milliren, Carly E., Qi, Jingjing, Geng, Linda N., McComsey, Grace A., Cairns, Charles B., Baden, Lindsey R., Schaenman, Joanna, Shaw, Albert C., Samaha, Hady, Seyfert-Margolis, Vicki, Krammer, Florian, Rosen, Lindsey B., Steen, Hanno, Syphurs, Caitlin, Dandekar, Ravi, Shannon, Casey P., Sekaly, Rafick P., Ehrlich, Lauren I. R., Corry, David B., Kheradmand, Farrah, Atkinson, Mark A., Brakenridge, Scott C., Higuita, Nelson I. Agudelo, Metcalf, Jordan P., Hough, Catherine L., Messer, William B., Pulendran, Bali, Nadeau, Kari C., Davis, Mark M., Sesma, Ana Fernandez, Simon, Viviana, van Bakel, Harm, Kim-Schulze, Seunghee, Hafler, David A., Levy, Ofer, Kraft, Monica, Bime, Chris, Haddad, Elias K., Calfee, Carolyn S., Erle, David J., Langelier, Charles R., Eckalbar, Walter, Bosinger, Steven E., Peters, Bjoern, Kleinstein, Steven H., Reed, Elaine F., Augustine, Alison D., Diray-Arce, Joann, Maecker, Holden T., Altman, Matthew C., Montgomery, Ruth R., Becker, Patrice M., and Rouphael, Nadine

Published
2024
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5. Phenotypes of disease severity in a cohort of hospitalized COVID-19 patients: Results from the IMPACC study

Author

Ozonoff, Al, Schaenman, Joanna, Jayavelu, Naresh Doni, Milliren, Carly E, Calfee, Carolyn S, Cairns, Charles B, Kraft, Monica, Baden, Lindsey R, Shaw, Albert C, Krammer, Florian, van Bakel, Harm, Esserman, Denise A, Liu, Shanshan, Sesma, Ana Fernandez, Simon, Viviana, Hafler, David A, Montgomery, Ruth R, Kleinstein, Steven H, Levy, Ofer, Bime, Christian, Haddad, Elias K, Erle, David J, Pulendran, Bali, Nadeau, Kari C, Davis, Mark M, Hough, Catherine L, Messer, William B, Higuita, Nelson I Agudelo, Metcalf, Jordan P, Atkinson, Mark A, Brakenridge, Scott C, Corry, David, Kheradmand, Farrah, Ehrlich, Lauren IR, Melamed, Esther, McComsey, Grace A, Sekaly, Rafick, Diray-Arce, Joann, Peters, Bjoern, Augustine, Alison D, Reed, Elaine F, Altman, Matthew C, Becker, Patrice M, Rouphael, Nadine, Bime, Chris, McEnaney, Kerry, Barton, Brenda, Lentucci, Claudia, Saluvan, Mehmet, Chang, Ana C, Hoch, Annmarie, Albert, Marisa, Shaheen, Tanzia, Kho, Alvin T, Thomas, Sanya, Chen, Jing, Murphy, Maimouna D, Cooney, Mitchell, Presnell, Scott, and Fragiadakis, Gabriela K

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Infectious Diseases, Emerging Infectious Diseases, Lung, Genetics, Clinical Research, Coronaviruses, Prevention, Good Health and Well Being, COVID-19, Creatinine, Female, Hospitalization, Humans, Male, Phenotype, Prospective Studies, RNA, Viral, SARS-CoV-2, Severity of Illness Index, Troponin, Post-Acute COVID-19 Syndrome, Viral load, Antibody, IMPACC study group members, Public Health and Health Services, Clinical sciences, Epidemiology
Abstract

BackgroundBetter understanding of the association between characteristics of patients hospitalized with coronavirus disease 2019 (COVID-19) and outcome is needed to further improve upon patient management.MethodsImmunophenotyping Assessment in a COVID-19 Cohort (IMPACC) is a prospective, observational study of 1164 patients from 20 hospitals across the United States. Disease severity was assessed using a 7-point ordinal scale based on degree of respiratory illness. Patients were prospectively surveyed for 1 year after discharge for post-acute sequalae of COVID-19 (PASC) through quarterly surveys. Demographics, comorbidities, radiographic findings, clinical laboratory values, SARS-CoV-2 PCR and serology were captured over a 28-day period. Multivariable logistic regression was performed.FindingsThe median age was 59 years (interquartile range [IQR] 20); 711 (61%) were men; overall mortality was 14%, and 228 (20%) required invasive mechanical ventilation. Unsupervised clustering of ordinal score over time revealed distinct disease course trajectories. Risk factors associated with prolonged hospitalization or death by day 28 included age ≥ 65 years (odds ratio [OR], 2.01; 95% CI 1.28-3.17), Hispanic ethnicity (OR, 1.71; 95% CI 1.13-2.57), elevated baseline creatinine (OR 2.80; 95% CI 1.63- 4.80) or troponin (OR 1.89; 95% 1.03-3.47), baseline lymphopenia (OR 2.19; 95% CI 1.61-2.97), presence of infiltrate by chest imaging (OR 3.16; 95% CI 1.96-5.10), and high SARS-CoV2 viral load (OR 1.53; 95% CI 1.17-2.00). Fatal cases had the lowest ratio of SARS-CoV-2 antibody to viral load levels compared to other trajectories over time (p=0.001). 589 survivors (51%) completed at least one survey at follow-up with 305 (52%) having at least one symptom consistent with PASC, most commonly dyspnea (56% among symptomatic patients). Female sex was the only associated risk factor for PASC.InterpretationIntegration of PCR cycle threshold, and antibody values with demographics, comorbidities, and laboratory/radiographic findings identified risk factors for 28-day outcome severity, though only female sex was associated with PASC. Longitudinal clinical phenotyping offers important insights, and provides a framework for immunophenotyping for acute and long COVID-19.FundingNIH.

Published
2022

6. A pre-vaccination immune metabolic interplay determines the protective antibody response to a dengue virus vaccine

Author

Pelletier, Adam-Nicolas, Sanchez, Gabriela Pacheco, Izmirly, Abdullah, Watson, Mark, Di Pucchio, Tiziana, Carvalho, Karina Inacio, Filali-Mouhim, Abdelali, Paramithiotis, Eustache, Timenetsky, Maria do Carmo S.T., Precioso, Alexander Roberto, Kalil, Jorge, Diamond, Michael S., Haddad, Elias K., Kallas, Esper G., and Sekaly, Rafick Pierre

Published
2024
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8. HIV vaccine candidate efficacy in female macaques mediated by cAMP-dependent efferocytosis and V2-specific ADCC

Author

Bissa, Massimiliano, Kim, Sohyoung, Galli, Veronica, Fourati, Slim, Sarkis, Sarkis, Arakelyan, Anush, de Castro, Isabela Silva, Rahman, Mohammad Arif, Fujiwara, Saori, Vaccari, Monica, Tomalka, Jeffrey A., Stamos, James D., Schifanella, Luca, Gorini, Giacomo, Moles, Ramona, Gutowska, Anna, Ferrari, Guido, Lobanov, Alexei, Montefiori, David C., Nelson, George W., Cam, Margaret C., Chakhtoura, Marita, Haddad, Elias K., Doster, Melvin N., McKinnon, Katherine, Brown, Sophia, Venzon, David J., Choo-Wosoba, Hyoyoung, Breed, Matthew W., Killoran, Kristin E., Kramer, Joshua, Margolis, Leonid, Sekaly, Rafick P., Hager, Gordon L., and Franchini, Genoveffa

Published
2023
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11. Immunophenotyping assessment in a COVID-19 cohort (IMPACC): A prospective longitudinal study

Author

Rouphael, Nadine, Maecker, Holden, Montgomery, Ruth R, Diray-Arce, Joann, Kleinstein, Steven H, Altman, Matthew C, Bosinger, Steven E, Eckalbar, Walter, Guan, Leying, Hough, Catherine L, Krammer, Florian, Langelier, Charles, Levy, Ofer, McEnaney, Kerry, Peters, Bjoern, Rahman, Adeeb, Rajan, Jayant V, Sigelman, Steven, Steen, Hanno, van Bakel, Harm, Ward, Alyssa, Wilson, Michael R, Woodruff, Prescott, Zamecnik, Colin R, Augustine, Alison D, Ozonoff, Al, Reed, Elaine F, Becker, Patrice M, Higuita, Nelson Agudelo, Atkinson, Mark A, Baden, Lindsey R, Bime, Christian, Brakenridge, Scott C, Calfee, Carolyn S, Cairns, Charles B, Corry, David, Davis, Mark M, Ehrlich, Lauren IR, Haddad, Elias K, Erle, David J, Fernandez-Sesma, Ana, Hafler, David A, Kheradmand, Farrah, Kraft, Monica, McComsey, Grace A, Melamed, Esther, Messer, William, Metcalf, Jordan, Nadeau, Kari C, Pulendran, Bali, Sarwal, Minnie, Schaenman, Joanna, Sekaly, Rafick, Shaw, Albert C, and Simon, Viviana

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Clinical Research, Biomarkers, COVID-19, Computational Biology, Data Analysis, Gene Expression Profiling, Hospitalization, Humans, Immunophenotyping, Longitudinal Studies, Molecular Diagnostic Techniques, Prospective Studies, Proteomics, SARS-CoV-2, United States, IMPACC Manuscript Writing Team, IMPACC Network Steering Committee, Clinical sciences, Immunology
Abstract

The IMmunoPhenotyping Assessment in a COVID-19 Cohort (IMPACC) is a prospective longitudinal study designed to enroll 1000 hospitalized patients with COVID-19 (NCT04378777). IMPACC collects detailed clinical, laboratory and radiographic data along with longitudinal biologic sampling of blood and respiratory secretions for in depth testing. Clinical and lab data are integrated to identify immunologic, virologic, proteomic, metabolomic and genomic features of COVID-19-related susceptibility, severity and disease progression. The goals of IMPACC are to better understand the contributions of pathogen dynamics and host immune responses to the severity and course of COVID-19 and to generate hypotheses for identification of biomarkers and effective therapeutics, including optimal timing of such interventions. In this report we summarize the IMPACC study design and protocols including clinical criteria and recruitment, multi-site standardized sample collection and processing, virologic and immunologic assays, harmonization of assay protocols, high-level analyses and the data sharing plans.

Published
2021

12. Trends and Outcomes of Antegrade Dissection and Re-Entry in Chronic Total Occlusion Percutaneous Coronary Intervention

Author

Rempakos, Athanasios, Alexandrou, Michaella, Simsek, Bahadir, Kostantinis, Spyridon, Karacsonyi, Judit, Mutlu, Deniz, Ybarra, Luiz F., Bagur, Rodrigo, Choi, James W., Poommipanit, Paul, Khatri, Jaikirshan J., Davies, Rhian, Benton, Stewart, Gorgulu, Sevket, Jaffer, Farouc A., Chandwaney, Raj, Jaber, Wissam, Rinfret, Stephane, Nicholson, William, Azzalini, Lorenzo, Kearney, Kathleen E., Kerrigan, Jimmy L., Haddad, Elias V., Alaswad, Khaldoon, Basir, Mir B., Krestyaninov, Oleg, Khelimskii, Dmitrii, Abi-Rafeh, Nidal, ElGuindy, Ahmed, Goktekin, Omer, Rangan, Bavana V., Mastrodemos, Olga C., Al-Ogaili, Ahmed, Allana, Salman S., Sandoval, Yader, Burke, M. Nicholas, and Brilakis, Emmanouil S.

Published
2023
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13. Impact of calcium on the procedural techniques and outcomes of chronic total occlusion percutaneous coronary intervention

Author

Kostantinis, Spyridon, Rempakos, Athanasios, Simsek, Bahadir, Karacsonyi, Judit, Allana, Salman S., Alexandrou, Michaella, Gorgulu, Sevket, Alaswad, Khaldoon, Basir, Mir Babar, Davies, Rhian E., Benton, Stewart M., Jr, Krestyaninov, Oleg, Khelimskii, Dmitrii, Frizzell, Jarrod, Ybarra, Luiz F., Bagur, Rodrigo, Reddy, Niranjan, Kerrigan, Jimmy L., Haddad, Elias V., Love, Michael, Elbarouni, Basem, Soylu, Korhan, Yildirim, Ufuk, Dattilo, Philip, Azzalini, Lorenzo, Kearney, Kathleen, Sadek, Yasser, ElGuindy, Ahmed M., Abi Rafeh, Nidal, Goktekin, Omer, Mastrodemos, Olga C., Rangan, Bavana V., Sandoval, Yader, Burke, M. Nicholas, and Brilakis, Emmanouil S.

Published
2023
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14. An active HIV reservoir during ART is associated with maintenance of HIV-specific CD8+ T cell magnitude and short-lived differentiation status

Author

Takata, Hiroshi, Mitchell, Julie L., Pacheco, Julian, Pagliuzza, Amélie, Pinyakorn, Suteeraporn, Buranapraditkun, Supranee, Sacdalan, Carlo, Leyre, Louise, Nathanson, Sam, Kakazu, Juyeon C., Intasan, Jintana, Prueksakaew, Peeriya, Chomchey, Nitiya, Phanuphak, Nittaya, de Souza, Mark, Haddad, Elias K., Rolland, Morgane, Tovanabutra, Sodsai, Vasan, Sandhya, Hsu, Denise C., Chomont, Nicolas, and Trautmann, Lydie

Published
2023
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15. Multi-omic longitudinal study reveals immune correlates of clinical course among hospitalized COVID-19 patients

Author

Abraham, James, Adkisson, Michael, Albert, Marisa, Altamirano, Luz Torres, Alvarenga, Bonny, Anderson, Matthew L., Anderson, Evan J., Arnett, Azlann, Asashima, Hiromitsu, Atkinson, Mark A., Baden, Lindsey R., Barton, Brenda, Beach, Katherine, Beagle, Elizabeth, Becker, Patrice M., Bell, Matthew R., Bernui, Mariana, Bime, Christian, Boddapati, Arun Kumar, Booth, J. Leland, Borresen, Brittney, Brakenridge, Scott C., Bristow, Laurel, Bryant, Robert, Calfee, Carolyn S., Carreño, Juan Manuel, Carrillo, Sidney, Chak, Suzanna, Chang, Iris, Connors, Jennifer, Conway, Michelle, Corry, David B., Cowan, David, Croen, Brett, Dela Cruz, Charles S., Cusimano, Gina, Eaker, Lily, Edwards, Carolyn, Ehrlich, Lauren I.R., Elashoff, David, Erickson, Heidi, Erle, David J., Farhadian, Shelli, Farrugia, Keith, Fatou, Benoit, Fernandes, Andrea, Fernandez-Sesma, Ana, Fragiadakis, Gabriela K., Furukawa, Sara, Geltman, Janelle N., Ghale, Rajani, Bermúdez González, Maria Carolina, Goonewardene, I. Michael, Guerrero, Estella Sanchez, Guirgis, Faheem W., Hafler, David A., Hamilton, Sydney, Harris, Paul, Hayati, Arash Nemati, Hendrickson, Carolyn M., Agudelo Higuita, Nelson I., Hodder, Thomas, Holland, Steven M., Hough, Catherine L., Huerta, Christopher, Hurley, Kerin C., Hutton, Scott R., Iwasaki, Akiko, Jauregui, Alejandra, Jha, Meenakshi, Johnson, Brandi, Joyner, David, Kangelaris, Kirsten N., Kelly, Geoffrey, Khalil, Zain, Khan, Zenab, Kheradmand, Farrah, Kim, James N., Kimura, Hiroki, Ko, Albert I., Kohr, Bernard, Kraft, Monica, Krummel, Matthew, Kutzler, Michele A., Lasky-Su, Jessica, Lee, Serena, Lee, Deanna, Leipold, Michael, Lentucci, Claudia, Leroux, Carolyn, Lin, Edward, Liu, Shanshan, Love, Christina, Lu, Zhengchun, Maliskova, Lenka, Manning, Brittany Roth, Manohar, Monali, Martens, Mark, McComsey, Grace A., McEnaney, Kerry, McLin, Renee, Melamed, Esther, Melnyk, Nataliya, Mendez, Kevin, Messer, William B., Metcalf, Jordan P., Michelotti, Gregory, Mick, Eran, Mohanty, Subhasis, Mosier, Jarrod, Mulder, Lubbertus C.F., Murphy, Maimouna, Nadeau, Kari R.C., Nelson, Ebony, Nelson, Allison, Nguyen, Viet, Oberhaus, Jordan, Panganiban, Bernadine, Pellegrini, Kathryn L., Pickering, Harry C., Powell, Debra L., Presnell, Scott, Pulendran, Bali, Rahman, Adeeb H., Rashid, Ahmad Sadeed, Raskin, Ariel, Reed, Elaine F., Ribeiro, Susan Pereira, Rivera, Adreanne M., Rogers, Jacob E., Rogers, Angela, Rogowski, Brandon, Rooks, Rebecca, Rosenberg-Hasson, Yael, Rothman, Jessica, Rousseau, Justin F., Salehi-Rad, Ramin, Saluvan, Mehmet, Samaha, Hady, Schaenman, Joanna, Schunk, Ron, Semenza, Nicholas C., Sen, Subha, Sevransky, Jonathan, Seyfert-Margolis, Vicki, Shaheen, Tanzia, Shaw, Albert C., Sieg, Scott, Siegel, Sarah A.R., Sigal, Natalia, Siles, Nadia, Simmons, Brent, Simon, Viviana, Singh, Gagandeep, Sinko, Lauren, Smith, Cecilia M., Smolen, Kinga K., Song, Li-Zhen, Srivastava, Komal, Sullivan, Peter, Syphurs, Caitlin, Tcheou, Johnstone, Tegos, George P., Tharp, Greg K., Tong, Alexandra, Tsitsiklis, Alexandra, Ungaro, Ricardo F., Vaysman, Tatyana, Viode, Arthur, Vita, Randi, Wang, Xiaomei, Ward, Alyssa, Ward, Dawn C., Willmore, Andrew, Woloszczuk, Kyra, Wong, Kari, Woodruff, Prescott G., Xu, Leqi, van Haren, Simon, van de Guchte, Adriana, Zhao, Yujiao, Diray-Arce, Joann, Fourati, Slim, Doni Jayavelu, Naresh, Patel, Ravi, Maguire, Cole, Chang, Ana C., Dandekar, Ravi, Qi, Jingjing, Lee, Brian H., van Zalm, Patrick, Schroeder, Andrew, Chen, Ernie, Konstorum, Anna, Brito, Anderson, Gygi, Jeremy P., Kho, Alvin, Chen, Jing, Pawar, Shrikant, Gonzalez-Reiche, Ana Silvia, Hoch, Annmarie, Milliren, Carly E., Overton, James A., Westendorf, Kerstin, Cairns, Charles B., Rouphael, Nadine, Bosinger, Steven E., Kim-Schulze, Seunghee, Krammer, Florian, Rosen, Lindsey, Grubaugh, Nathan D., van Bakel, Harm, Wilson, Michael, Rajan, Jayant, Steen, Hanno, Eckalbar, Walter, Cotsapas, Chris, Langelier, Charles R., Levy, Ofer, Altman, Matthew C., Maecker, Holden, Montgomery, Ruth R., Haddad, Elias K., Sekaly, Rafick P., Esserman, Denise, Ozonoff, Al, Augustine, Alison D., Guan, Leying, Peters, Bjoern, and Kleinstein, Steven H.

Published
2023
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18. List of contributors

Author

Abi Rafeh, Nidal, primary, Agostoni, Pierfrancesco, additional, Akyuz, Sukru, additional, Alaswad, Khaldoon, additional, Ali, Ziad A., additional, Allana, Salman S., additional, Alraies, Chadi, additional, Araya, Mario, additional, Avran, Alexandre, additional, Azzalini, Lorenzo, additional, Babunashvili, Avtandil, additional, Banerjee, Subhash, additional, Bangalore, Sripal, additional, Bayani, Baktash, additional, Behnes, Michael, additional, Bhindi, Ravinay, additional, Boudou, Nicolas, additional, Božinović, Nenad Ž., additional, Bryniarski, Leszek, additional, Bufe, Alexander, additional, Buller, Christopher E., additional, Burke, M. Nicholas, additional, Cardoso, Pedro Pinto, additional, Carlino, Mauro, additional, Cavalcante, Joao L., additional, Chami, Tarek, additional, Chandwaney, Raj H., additional, Charitakis, Konstantinos, additional, Cheng, Victor Y., additional, Choi, James W., additional, Christiansen, Evald Høj, additional, Chugh, Yashasvi, additional, Colombo, Antonio, additional, Cosgrove, Claudia, additional, Croce, Kevin, additional, Daggubati, Ramesh, additional, Damas de los Santos, Félix, additional, Dautov, Rustem, additional, Davies, Rhian E., additional, de Martini, Tony, additional, Denktas, Ali E., additional, Dens, Joseph, additional, di Mario, Carlo, additional, Diletti, Roberto, additional, Dimitriadis, Zisis, additional, Doshi, Darshan, additional, Doshi, Parag, additional, Dou, Kefei, additional, Egred, Mohaned, additional, Elbarouni, Basem, additional, ElGuindy, Ahmed M., additional, Elhadidy, Amr, additional, Ellis, Stephen, additional, Escaned, Javier, additional, Fasseas, Panayotis, additional, Forouzandeh, Farshad, additional, Furkalo, Sergey, additional, Gagnor, Andrea, additional, Galassi, Alfredo R., additional, Gallino, Robert, additional, Garbo, Roberto, additional, Garcia, Santiago, additional, Gasparini, Gabriele, additional, Ge, Junbo, additional, Ge, Lei, additional, Goel, Pravin Kumar, additional, Goktekin, Omer, additional, Gonzalo, Nieves, additional, Gorgulu, Sevket, additional, Grancini, Luca, additional, Grantham, J. Aaron, additional, Guddeti, Raviteja, additional, Haddad, Elias V., additional, Hall, Allison B., additional, Hall, Jack J., additional, Halligan, Sean, additional, Hanna Quesada, Franklin Leonardo, additional, Hanratty, Colm, additional, Harb, Stefan, additional, Harding, Scott A., additional, Hatem, Raja, additional, Hildick-Smith, David, additional, Hill, Jonathan M., additional, Hirai, Taishi, additional, Iannaccone, Mario, additional, Jaber, Wissam, additional, Jaffer, Farouc A., additional, Jang, Yangsoo, additional, Jefferson, Brian K., additional, Jeremias, Allen, additional, Jussila, Risto, additional, Kakouros, Nikolaos, additional, Kalnins, Artis, additional, Kalra, Sanjog, additional, Kalyanasundaram, Arun, additional, Kandzari, David E., additional, Kao, Hsien-Li, additional, Karacsonyi, Judit, additional, Karmpaliotis, Dimitri, additional, Kassem, Hussien Heshmat, additional, Kearney, Kathleen, additional, Kerrigan, Jimmy, additional, Khatri, Jaikirshan, additional, Khelimskii, Dmitrii, additional, Kirtane, Ajay J., additional, Knaapen, Paul, additional, Kostantinis, Spyridon, additional, Koutouzis, Michalis, additional, Kovacic, Mihajlo, additional, Krestyaninov, Oleg, additional, Kumar, A.V. Ganesh, additional, Kumar N., Prathap, additional, Kunkel, Katherine J., additional, Lamelas, Pablo Manuel, additional, Lee, Seung-Whan, additional, Lefevre, Thierry, additional, Leibundgut, Gregor, additional, Lembo, Nicholas J., additional, Leon, Martin, additional, Lesser, John R., additional, Leung, Raymond, additional, Lim, Soo-Teik, additional, Lo, Sidney Tsz Ho, additional, Lombardi, William, additional, Luna, Michael, additional, Mahmud, Ehtisham, additional, Mahowald, Madeline K., additional, Maran, Anbukarasi, additional, Marmagkiolis, Konstantinos, additional, Martins Filho, Evandro, additional, Mashayekhi, Kambis, additional, McEntegart, Margaret B., additional, Megaly, Michael, additional, Meraj, Perwaiz, additional, Michalis, Lampros, additional, Milkas, Anastasios N., additional, Mogabgab, Owen, additional, Moses, Jeffrey, additional, Munawar, Muhammad, additional, Murad, Bilal, additional, Nap, Alexander, additional, Navarro, Andres, additional, Nicholson, William J., additional, Øksnes, Anja, additional, Olivecrona, Göran, additional, Omer, Mohamed A., additional, Oreglia, Jacopo Andrea, additional, Padilla, Lucio, additional, Patel, Mitul P., additional, Patel, Rajan A.G., additional, Patel, Taral, additional, Pershad, Ashish, additional, Pinto, Duane, additional, Poommipanit, Paul, additional, Postu, Marin, additional, Potluri, Srini, additional, Pyxaras, Stylianos, additional, Quadros, Alexandre Schaan de, additional, Ragosta, Michael, additional, Rao, Sunil V., additional, Rao, Vithala Surya Prakasa, additional, Rathore, Sudhir, additional, Reifart, Joerg, additional, Rempakos, Athanasios, additional, Rier, Jeremy, additional, Riley, Robert, additional, Rinfret, Stéphane, additional, Russo, Juan J., additional, Saghatelyan, Meruzhan, additional, Sandhu, Gurpreet S., additional, Sandoval, Yader, additional, Santiago, Ricardo, additional, Sapontis, James, additional, Shah, Alpesh, additional, Shlofmitz, Evan, additional, Shunk, Kendrick A., additional, Sianos, George, additional, Simsek, Bahadir, additional, Smith, Elliot J., additional, Spaedy, Anthony, additional, Spratt, James, additional, Strange, Julian W., additional, Strauss, Bradley, additional, Tajti, Péter, additional, Tamez, Hector, additional, Tammam, Khalid O., additional, Thompson, Craig A., additional, Toma, Aurel, additional, Toma, Catalin, additional, Tsiafoutis, Ioannis, additional, Tsuchikane, Etsuo, additional, Ungi, Imre, additional, Uretsky, Barry F., additional, Vlachojannis, Georgios J., additional, Vo, Minh Nhat, additional, Vu, Hoang Vu, additional, Walsh, Simon, additional, Weilenmann, Daniel, additional, Werner, Gerald, additional, Wójcik, Jarosław, additional, Wollmuth, Jason, additional, Wu, Eugene B., additional, Wyman, R. Michael, additional, Xenogiannis, Iosif, additional, Xu, Bo, additional, Yamane, Masahisa, additional, Ybarra, Luiz F., additional, and Yeh, Robert W., additional

Published
2023
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19. Abstract 12054: Activated Clotting Time and Outcomes of Chronic Total Occlusion Percutaneous Coronary Intervention: Insights From the PROGRESS-CTO Registry

Author

Simsek, Bahadir, Rempakos, Athanasios, Kostantinis, Spyridon, Alexandrou, Michaella, gorgulu, sevket, Alaswad, Khaldoon, Frizzell, Jarrod D, Yildirim, Ufuk, Poommipanit, Paul, Aygul, Nazif, Abi Rafeh, Nidal, Bagur, Rodrigo, Davies, Rhian, GOKTEKIN, OMER, Choi, James W, Reddy, Niranjan, Haddad, Elias, Kerrigan, Jimmy, Mutlu, Deniz, Mastrodemos, Olga, Rangan, Bavana V, Karacsonyi, Judit, Allana, Salman S, Kearney, Kathleen E, Sandoval, Yader, Burke, M Nicholas, Brilakis, Emmanouil S, and Azzalini, Lorenzo

Published
2023
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20. Subcapsular renal transplant hematoma mimicking acute tubular necrosis

Author

Akel Rhea, Haddad Elias, and Hachem Kamal

Subjects
acute tubular necrosis, Doppler, renal transplant, subscapular hematoma, ultrasound, Medicine, Medicine (General), R5-920
Abstract

Key Clinical Message Kidney transplantation is the treatment of choice for patients with end‐stage renal disease. However, it is associated with serious potential complications, one of which is the subcapsular renal transplant hematoma. Ultrasound is the major imaging tools in the evaluation of early graft complications. We discuss the case of a patient who underwent a living‐donor kidney transplantation, complicated of acute kidney injury documented on serial blood tests with an elevation of creatinine levels and oliguria. Ultrasonography showed the presence of a subcapsular renal hematoma, associated with the same spectral characterizations of an acute tubular necrosis with a high resistive index on Color Doppler Ultrasonography Study of renal arteries. The patient underwent an emergent surgical evacuation of the subcapsular renal hematoma. A repeat ultrasonography showed the complete resolution of the subcapsular renal hematoma with normal resistive index. During the following days, diuresis was back to normal and serial blood tests showed normal levels of creatinine. This case report highlights the importance of Ultrasonography in detecting subcapsular hematomas that could be a reversible cause of acute kidney injury and acute tubular necrosis in the setting of renal transplant.

Published
2023
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21. Effects of neutron radiation on the optical and structural properties of blue and green emitting plastic scintillators

Author

Baranov, Vladimir, Davydov, Yuri, Erasmus, Rudolph, Kureba, Chamunorwa O, Lekalakala, Nthabiseng, Masuku, Thabo C, Mdhluli, Joyful E, Mellado, Bruce, Mokgatitswane, Gaogalalwe, Sideras-Haddad, Elias, Vasilyev, Ilya, and Zhmurin, Petr N

Subjects
Physics - Instrumentation and Detectors
Abstract

We report on the optical and structural properties of plastic scintillators irradiated with neutron beams produced by the IBR-2 reactor of the Frank Laboratory of Neutron Physics in JINR, Dubna. Blue UPS-923A and green plastic scintillators were irradiated with neutron fluence ranging from 10$^{13}$ to 10$^{17}$ n/cm$^2$. Discolouring in the plastic scintillators was observed after irradiation. The effects of radiation damage on the optical and structural properties of the samples were characterized by conducting light yield, light transmission, light fluorescence and Raman spectroscopy studies. The results showed that neutron radiation induced damage in the material. The disappearance of the Raman peak features in green scintillators at frequencies of 1165.8, 1574.7 and 1651.2 cm$^{-1}$ revealed significant structural alterations due to neutron bombardment. Losses in fluorescence intensity, light yield and light transmission in the plastic scintillators were observed., Comment: 19 pages, 9 figures

Published
2018
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23. Abstract 12133: Coronary Artery Perforation During Chronic Total Occlusion Percutaneous Coronary Intervention: Incidence, Mechanisms, Treatment and Outcomes

Author

Kostantinis, Spyridon, Simsek, Bahadir, Karacsonyi, Judit, Alaswad, Khaldoon, Krestyaninov, Oleg, Khelimskii, Dmitrii, Karmpaliotis, Dimitrios, Jaffer, Farouc A, Khatri, Jaikirshan, Poommipanit, Paul, Jaber, Wissam, Rinfret, Stephane, Nicholson, William, PATEL, MITUL P, Mahmud, Ehtisham, KUTUZIS, MICHAEL, Tsiafoutis, Ioannis, Benton, Stewart M, Jr, Davies, Rhian, Toma, Catalin, Kerrigan, Jimmy, Haddad, Elias, Abi Rafeh, Nidal, El Guindy, Ahmed, Goktekin, Omer, Mastrodemos, Olga, Rangan, Bavana V, Burke, M Nicholas, and Brilakis, Emmanouil S

Published
2022
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24. Practices and Rules of 16th Century Genoese Gilding: Exploring Gold Leaf Thickness and Caratage through X-ray and Ion Beam Techniques.

Author

Ciarlo, Letizia, Chiari, Massimo, Galassi, Maria Clelia, Ferretti, Maurizio, Sideras-Haddad, Elias, Zucchiatti, Alessandro, and Castagnotto, Elena

Subjects
RUTHERFORD backscattering spectrometry, X-ray fluorescence, ION beams, PROTON accelerators, PARTICLE induced X-ray emission, MORDANTS
Abstract

This study investigates the practices and rules of Genoese gilding, drawing insights from a 16th-century manuscript containing regulations for gold leaf production. Employing X-ray and ion beam techniques, we quantitatively assess the manuscript's gold leaf thickness without destructive sampling. Artisanal goldbeater-produced leaves of different thicknesses, applied with a guazzo or mordant technique, served as standards. Further analysis of samples with unknown thickness from the furniture of Palazzo Spinola di Pellicceria in Genoa (Italy) has confirmed the method's applicability to practical cases. External beam Rutherford backscattering spectrometry (RBS) and particle-induced X-ray emission (PIXE) analyses were carried out using 3 MeV protons at the LABEC accelerator laboratory in Florence. A linear relationship between Gold Lα peak yield and leaf thickness, as measured by RBS, has been established for optimal calibration of portable or hand-held X-Ray fluorescence (XRF) instrumentation for in situ measurements. Moreover, the caratage of the gold foil preserved in the manuscript has been assessed. [ABSTRACT FROM AUTHOR]

Published
2024
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27. Activated Clotting Time and Outcomes of Chronic Total Occlusion Percutaneous Coronary Intervention: Insights From the PROGRESS-CTO Registry

Author

Simsek, Bahadir, primary, Rempakos, Athanasios, additional, Kostantinis, Spyridon, additional, Alexandrou, Michaella, additional, Gorgulu, Sevket, additional, Alaswad, Khaldoon, additional, Frizzell, Jarrod, additional, Yildirim, Ufuk, additional, Poommipanit, Paul, additional, Aygul, Nazif, additional, Abi Rafeh, Nidal, additional, Bagur, Rodrigo, additional, Davies, Rhian, additional, Goktekin, Omer, additional, Choi, James, additional, Reddy, Niranjan, additional, Dattilo, Philip, additional, Kerrigan, Jimmy, additional, Haddad, Elias, additional, Mastrodemos, Olga, additional, Rangan, Bavana, additional, Karacsonyi, Judit, additional, Allana, Salman, additional, Kearney, Kathleen, additional, Sandoval, Yader, additional, Burke, M. Nicholas, additional, Brilakis, Emmanouil, additional, and Azzalini, Lorenzo, additional

Published
2023
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28. Corrigendum to “Phenotypes of disease severity in a cohort of hospitalized COVID-19 patients: results from the IMPACC study” [eBioMedicine 83 (2022) 104208]

Author

Ozonoff, Al, primary, Schaenman, Joanna, additional, Jayavelu, Naresh Doni, additional, Milliren, Carly E., additional, Calfee, Carolyn S., additional, Cairns, Charles B., additional, Kraft, Monica, additional, Baden, Lindsey R., additional, Shaw, Albert C., additional, Krammer, Florian, additional, van Bakel, Harm, additional, Esserman, Denise A., additional, Liu, Shanshan, additional, Sesma, Ana Fernandez, additional, Simon, Viviana, additional, Hafler, David A., additional, Montgomery, Ruth R., additional, Kleinstein, Steven H., additional, Levy, Ofer, additional, Bime, Chris, additional, Haddad, Elias K., additional, Erle, David J., additional, Pulendran, Bali, additional, Nadeau, Kari C., additional, Davis, Mark M., additional, Hough, Catherine L., additional, Messer, William B., additional, Agudelo Higuita, Nelson I., additional, Metcalf, Jordan P., additional, Atkinson, Mark A., additional, Brakenridge, Scott C., additional, Corry, David, additional, Kheradmand, Farrah, additional, Ehrlich, Lauren I.R., additional, Melamed, Esther, additional, McComsey, Grace A., additional, Sekaly, Rafick, additional, Diray-Arce, Joann, additional, Peters, Bjoern, additional, Augustine, Alison D., additional, Reed, Elaine F., additional, Altman, Matthew C., additional, Becker, Patrice M., additional, and Rouphael, Nadine, additional

Published
2023
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29. Magnetization Effects in Proton Micro-Irradiated Diamond

Author

Makgato, Thuto, Sideras-Haddad, Elias, Shrivastava, Sanjiv, Madhuku, Morgan, Sekonya, Kamela, Pineda-Vargas, Carlos A, and Jourbert, Daniel

Subjects
Condensed Matter - Materials Science, Condensed Matter - Other Condensed Matter
Abstract

We report the magnetic response of high purity type IIa single crystal CVD diamond following high energy irradiation by 2.2 MeV proton micro-beams, produced using Nuclear Microprobe techniques. Post-irradiation microanalysis is achieved using Atomic Force, Magnetic Force and Electrostatic Force Microscopy (AFM, MFM & EFM) as well as Raman spectroscopy. Comparison between MFM and EFM measurements at zero electrical bias is used to preclude artefacts of electrostatic origin suggesting the presence of magnetic states in the microscale regions induced by proton micro-irradiation. Analysis of the irradiated regions using probe polarization dependent magnetization measurements shows an irradiation induced magnetic response consistent with ferromagnetic ordering at room temperature. Structural characterization of the micro-irradiated regions using micro-Raman spectroscopy indicates a correlation between formation of the sp2 carbon phase in the diamond matrix with the scale of the observed magnetization, in the investigated experimental regime., Comment: 22 Pages, 8 Figures, 1 Table

Published
2014

31. Effects of persistent modulation of intestinal microbiota on SIV/HIV vaccination in rhesus macaques

Author

Klatt, Nichole R., Broedlow, Courtney, Osborn, Jessica M., Gustin, Andrew T., Dross, Sandra, O’Connor, Megan A., Coronado, Ernesto, Barnette, Philip, Hensley-McBain, Tiffany, Zevin, Alexander S., Muir, Roshell, Roederer, Alexander, Wangari, Solomon, Iwayama, Naoto, Ahrens, Chul Y., Smedley, Jeremy, Moats, Cassandra, Lynch, Rebecca M., Haddad, Elias K., Haigwood, Nancy L., Fuller, Deborah H., and Manuzak, Jennifer A.

Published
2021
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32. Plasmacytoid dendritic cells sense HIV replication before detectable viremia following treatment interruption

Author

Mitchell, Julie L., Takata, Hiroshi, Muir, Roshell, Colby, Donn J., Kroon, Eugene, Crowell, Trevor A., Sacdalan, Carlo, Pinyakorn, Suteeraporn, Puttamaswin, Suwanna, Benjapornpong, Khunthalee, Trichavaroj, Rapee, Tressler, Randall L., Fox, Lawrence, Polonis, Victoria R., Bolton, Diane L., Maldarelli, Frank, Lewin, Sharon R., Haddad, Elias K., Phanuphak, Praphan, Robb, Merlin L., Michael, Nelson L., de Souza, Mark, Phanuphak, Nittaya, Ananworanich, Jintanat, and Trautmann, Lydie

Subjects
Thermo Fisher Scientific Inc., Highly active antiretroviral therapy -- Health aspects, Vorinostat -- Health aspects, Viremia -- Health aspects, HIV tests -- Health aspects, HIV -- Health aspects, Infection -- Health aspects, Dendritic cells -- Health aspects, Maraviroc -- Health aspects, Virus replication -- Health aspects, Scientific equipment industry -- Health aspects, Health care industry
Abstract

Plasmacytoid dendritic cells (pDCs) are robust producers of IFN[alpha] and one of the first immune cells to respond to SIV infection. To elucidate responses to early HIV-1 replication, we studied blood pDCs in 29 HIV-infected participants who initiated antiretroviral therapy during acute infection and underwent analytic treatment interruption (ATI). We observed an increased frequency of partially activated pDCs in the blood before detection of HIV RNA. Concurrent with peak pDC frequency, we detected a transient decline in the ability of pDCs to produce IFN[alpha] in vitro, which correlated with decreased phosphorylation of IFN regulatory factory 7 (IRF7) and NF-[kappa]B. The levels of phosphorylated IRF7 and NF-[kappa]B inversely correlated with plasma IFNA2 levels, implying that pDCs were refractory to in vitro stimulation after IFN[alpha] production in vivo. After ATI, decreased expression of IFN genes in pDCs inversely correlated with the time to viral detection, suggesting that pDC IFN loss is part of an effective early immune response. These data from a limited cohort provide a critical first step in understanding the earliest immune response to HIV-1 and suggest that changes in blood pDC frequency and function can be used as an indicator of viral replication before detectable plasma viremia., Introduction Plasmacytoid dendritic cells (pDCs) are important mediators of the early innate immune response to viral infection through robust production of type I IFNs, particularly IFN[alpha] (1, 2). pDCs recognize [...]

Published
2020
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35. Host-microbe multiomic profiling reveals age-dependent immune dysregulation associated with COVID-19 immunopathology.

Author

Phan, Hoang Van, Tsitsiklis, Alexandra, Maguire, Cole P., Haddad, Elias K., Becker, Patrice M., Kim-Schulze, Seunghee, Lee, Brian, Chen, Jing, Hoch, Annmarie, Pickering, Harry, van Zalm, Patrick, Altman, Matthew C., Augustine, Alison D., Calfee, Carolyn S., Bosinger, Steve, Cairns, Charles B., Eckalbar, Walter, Guan, Leying, Jayavelu, Naresh Doni, and Kleinstein, Steven H.

Abstract

Age is a major risk factor for severe coronavirus disease 2019 (COVID-19), yet the mechanisms behind this relationship have remained incompletely understood. To address this, we evaluated the impact of aging on host immune response in the blood and the upper airway, as well as the nasal microbiome in a prospective, multicenter cohort of 1031 vaccine-naïve patients hospitalized for COVID-19 between 18 and 96 years old. We performed mass cytometry, serum protein profiling, anti–severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibody assays, and blood and nasal transcriptomics. We found that older age correlated with increased SARS-CoV-2 viral abundance upon hospital admission, delayed viral clearance, and increased type I interferon gene expression in both the blood and upper airway. We also observed age-dependent up-regulation of innate immune signaling pathways and down-regulation of adaptive immune signaling pathways. Older adults had lower naïve T and B cell populations and higher monocyte populations. Over time, older adults demonstrated a sustained induction of pro-inflammatory genes and serum chemokines compared with younger individuals, suggesting an age-dependent impairment in inflammation resolution. Transcriptional and protein biomarkers of disease severity differed with age, with the oldest adults exhibiting greater expression of pro-inflammatory genes and proteins in severe disease. Together, our study finds that aging is associated with impaired viral clearance, dysregulated immune signaling, and persistent and potentially pathologic activation of pro-inflammatory genes and proteins. Editor's summary: It is well-established that older adults are at increased risk of severe and fatal COVID-19, but the mechanisms underlying this susceptibility are not entirely clear. To better understand features associated with age and COVID-19 severity, Phan et al. comprehensively studied the immune response to SARS-CoV-2 in a large longitudinal clinical cohort. By integrating mass cytometry, serum proteomics, antibody assays, and transcriptional analysis, the authors found that age was associated with increased viral load, delayed viral clearance, and alterations to immune cell frequencies. Markers of disease severity, such as interleukin-6, were the most extreme in the oldest patients. Together, these data provide insight into why age is a major risk factor for severe COVID-19. —Courtney Malo [ABSTRACT FROM AUTHOR]

Published
2024
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36. Integrated longitudinal multi-omics study identifies immune programs associated with COVID-19 severity and mortality in 1152 hospitalized participants

Author

Gygi, Jeremy P., primary, Maguire, Cole, additional, Patel, Ravi K., additional, Shinde, Pramod, additional, Konstorum, Anna, additional, Shannon, Casey P., additional, Xu, Leqi, additional, Hoch, Annmarie, additional, Jayavelu, Naresh Doni, additional, Network, IMPACC, additional, Haddad, Elias K., additional, Reed, Elaine F., additional, Kraft, Monica, additional, McComsey, Grace A., additional, Metcalf, Jordan, additional, Ozonoff, Al, additional, Esserman, Denise, additional, Cairns, Charles B., additional, Rouphael, Nadine, additional, Bosinger, Steven E., additional, Kim-Schulze, Seunghee, additional, Krammer, Florian, additional, Rosen, Lindsey B., additional, van Bakel, Harm, additional, Wilson, Michael, additional, Eckalbar, Walter, additional, Maecker, Holden, additional, Langelier, Charles R., additional, Steen, Hanno, additional, Altman, Matthew C., additional, Montgomery, Ruth R., additional, Levy, Ofer, additional, Melamed, Esther, additional, Pulendran, Bali, additional, Diray-Arce, Joann, additional, Smolen, Kinga K., additional, Fragiadakis, Gabriela K., additional, Becker, Patrice M., additional, Augustine, Alison D., additional, Sekaly, Rafick P., additional, Ehrlich, Lauren I. R., additional, Fourati, Slim, additional, Peters, Bjoern, additional, Kleinstein, Steven H., additional, and Guan, Leying, additional

Published
2023
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38. TCT-422 Trends and Outcomes of Antegrade Dissection and Re-Entry in Chronic Total Occlusion Percutaneous Coronary Intervention

Author

Rempakos, Athanasios, primary, Alexandrou, Michaella, additional, Simsek, Bahadir, additional, Kostantinis, Spyridon, additional, Karacsonyi, Judit, additional, Mutlu, Deniz, additional, Ybarra, Luiz, additional, Bagur, Rodrigo, additional, Choi, James, additional, Poommipanit, Paul, additional, Khatri, Jaikirshan, additional, Davies, Rhian, additional, Benton, Stewart, additional, Gorgulu, Sevket, additional, Jaffer, Farouc, additional, Chandwaney, Raj, additional, Jaber, Wissam, additional, Rinfret, Stephane, additional, Nicholson, William, additional, Azzalini, Lorenzo, additional, Kerrigan, Jimmy, additional, Haddad, Elias, additional, Alaswad, Khaldoon, additional, Krestyaninov, Oleg, additional, Khelimskii, Dmitrii, additional, Rafeh, Nidal Abi, additional, Goktekin, Omer, additional, Rangan, Bavana, additional, Mastrodemos, Olga, additional, Al-Ogaili, Ahmed, additional, Allana, Salman, additional, Burke, M. Nicholas, additional, Sandoval, Yader, additional, and Brilakis, Emmanouil, additional

Published
2023
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40. Down-regulation of CTLA-4 by HIV-1 Nef protein.

Author

El-Far, Mohamed, Isabelle, Catherine, Chomont, Nicolas, Bourbonnière, Martin, Fonseca, Simone, Ancuta, Petronela, Peretz, Yoav, Chouikh, Younes, Halwani, Rabih, Schwartz, Olivier, Madrenas, Joaquín, Freeman, Gordon J, Routy, Jean-Pierre, Haddad, Elias K, and Sékaly, Rafick-Pierre

Subjects
Hela Cells, Endosomes, Lysosomes, Humans, HIV-1, Antigens, CD4, Recombinant Fusion Proteins, Transfection, Signal Transduction, Endocytosis, Down-Regulation, Amino Acid Motifs, nef Gene Products, Human Immunodeficiency Virus, Host-Pathogen Interactions, HEK293 Cells, CTLA-4 Antigen, CD4 Antigens, HeLa Cells, nef Gene Products, Human Immunodeficiency Virus, General Science & Technology
Abstract

HIV-1 Nef protein down-regulates several cell surface receptors through its interference with the cell sorting and trafficking machinery. Here we demonstrate for the first time the ability of Nef to down-regulate cell surface expression of the negative immune modulator CTLA-4. Down-regulation of CTLA-4 required the Nef motifs DD175, EE155 and LL165, all known to be involved in vesicle trafficking. Disruption of the lysosomal functions by pH-neutralizing agents prevented CTLA-4 down-regulation by Nef, demonstrating the implication of the endosomal/lysosomal compartments in this process. Confocal microscopy experiments visualized the co-localization between Nef and CTLA-4 in the early and recycling endosomes but not at the cell surface. Overall, our results provide a novel mechanism by which HIV-1 Nef interferes with the surface expression of the negative regulator of T cell activation CTLA-4. Down-regulation of CTLA-4 may contribute to the mechanisms by which HIV-1 sustains T cell activation, a critical step in viral replication and dissemination.

Published
2013

41. Anti-HIV antibody development up to 1 year after antiretroviral therapy initiation in acute HIV infection

Author

Mitchell, Julie L., Pollara, Justin, Dietze, Kenneth, Edwards, R. Whitney, Nohara, Junsuke, N'guessan, Kombo F., Zemil, Michelle, Buranapraditkun, Supranee, Takata, Hiroshi, Li, Yifan, Muir, Roshell, Kroon, Eugene, Pinyakorn, Suteeraporn, Jha, Shalini, Manasnayakorn, Sopark, Chottanapund, Suthat, Thantiworasit, Pattarawat, Prueksakaew, Peeriya, Ratnaratorn, Nisakorn, Nuntapinit, Bessara, Fox, Lawrence, Tovanabutra, Sodsai, Paquin-Proulx, Dominic, Wieczorek, Lindsay, Polonis, Victoria R., Maldarelli, Frank, Haddad, Elias K., Phanuphak, Praphan, Sacdalan, Carlo P., Rolland, Morgane, Phanuphak, Nittaya, Ananworanich, Jintanat, Vasan, Sandhya, Ferrari, Guido, and Trautmann, Lydie

Subjects
HIV antibodies -- Identification and classification, Immune response -- Observations, Antiviral agents -- Patient outcomes, HIV infection -- Development and progression -- Drug therapy, Health care industry
Abstract

Early initiation of antiretroviral therapy (ART) in acute HIV infection (AHI) is effective at limiting seeding of the HIV viral reservoir, but little is known about how the resultant decreased antigen load affects long-term Ab development after ART. We report here that Env-specific plasma antibody (Ab) levels and Ab-dependent cellular cytotoxicity (ADCC) increased during the first 24 weeks of ART and correlated with Ab levels persisting after 48 weeks of ART. Participants treated in AHI stage 1 had lower Env-specific Ab levels and ADCC activity on ART than did those treated later. Importantly, participants who initiated ART after peak viremia in AHI developed elevated cross-clade ADCC responses that were detectable 1 year after ART initiation, even though clinically undetectable viremia was reached by 24 weeks. These data suggest that there is more germinal center (GC) activity in the later stages of AHI and that Ab development continues in the absence of detectable viremia during the first year of suppressive ART. The development of therapeutic interventions that can enhance earlier development of GCs in AHI and Abs after ART initiation could provide important protection against the viral reservoir that is seeded in individuals treated early in the disease., Introduction Initiation of antiretroviral therapy (ART) during acute HIV infection (AHI) is associated with multiple benefits, including decreased HIV reservoir size (1-6) and preservation of a homogenous viral reservoir with [...]

Published
2022
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42. Development and validation of a scoring system for predicting clinical coronary artery perforation during percutaneous coronary intervention of chronic total occlusions: the PROGRESS-CTO perforation score

Author

Kostantinis, Spyridon, Şimşek, Bahadır, Karacsonyi, Judit, Alaswad, Khaldoon, Jaffer, Farouc A., Khatri, Jaikirshan J., Choi, James W., Jaber, Wissam, Rinfret, Stephane, Nicholson, William, Patel, Mitul P., Mahmud, Ehtisham, Toma, Catalin, Davies, Rhian E., Kerrigan, Jimmy L., Haddad, Elias V., Görgülü, Şevket, Abi-Rafeh, Nidal, ElGuindy, Ahmed M., Göktekin, Ömer, Allana, Salman, Burke, M. Nicholas, Mastrodemos, Olga C., Rangan, Bavana V., Brilakis, Emmanouil S., and Tıp Fakültesi

Subjects
Cardiology and Cardiovascular Medicine
Abstract

Background: Coronary artery perforation is a feared complication of chronic total occlusion (CTO) percutaneous coronary intervention (PCI) and often leads to serious adverse clinical events. Aims: We sought to develop a risk score to predict clinical coronary artery perforation in patients undergoing CTO PCI. Methods: We analysed clinical and angiographic parameters from 9,618 CTO PCIs in the Prospective Global Registry for the Study of Chronic Total Occlusion Intervention (PROGRESS-CTO). Logistic regression prediction modelling was used to identify variables independently associated with clinical perforation, and the model was internally validated with bootstrapping. Clinical coronary artery perforation was defined as any perforation requiring treatment. Results: The incidence of clinical coronary perforation was 3.8% (n=367). Five factors were independently associated with perforation and were included in the score: patient age ≥65 years +1 point (odds ratio [OR] 1.79, 95% confidence interval [CI]: 1.37-2.33), moderate/severe calcification +1 point (OR 1.85, 95% CI: 1.41-2.42), blunt/no stump +1 point (OR 1.45, 95% CI: 1.10-1.92), use of antegrade dissection and re-entry +1 point (OR 2.43, 95% CI: 1.61-3.69), and use of the retrograde approach +2 points (OR 4.02, 95% CI: 2.95-5.46). The resulting score showed acceptable performance on receiver operating characteristic (ROC) curve (area under the curve [AUC]: 0.741, 95% CI: 0.712-0.773). The Hosmer-Lemeshow test indicated a good fit (p=0.991), and internal validation with bootstrapping demonstrated good agreement with the model with observed AUC: 0.736 (95% bias-corrected CI: 0.706-0.767). Conclusions: The PROGRESS-CTO perforation score may be a useful tool for predicting clinical coronary perforation during CTO PCI.

Published
2023

43. D-34 | Peripheral Arterial Disease in Chronic Total Occlusion Percutaneous Coronary Intervention

Author

Alexandrou, Michaella, Rempakos, Thanasis (Athanasios), Mutlu, Deniz, Al-Ogaili, Ahmed, Carvalho, Pedro E.P., Strepkos, Dimitrios, Choi, James W., Poommipanit, Paul, Alaswad, Khaldoon, Basir, Babar B., Davies, Rhian E., Jaffer, Farouc A., Dattilo, Philip, Azzalini, Lorenzo, Aygul, Nazif, Chandwaney, Raj H., Jefferson, Brian Keith, Görgülü, Şevket, Khatri, Jaikirshan, Young, Laura, Krestyaninov, Oleg, Khelimskii, Dmitrii, Frizzell, Jarrod, Göktekin, Ömer, Rangan, Bavana V., Mastrodemos, Olga, Lee Kerrigan, Dr. Jimmy, Haddad, Elias Victor, Sadek Yass, Yasser Ahmed, Reddy, M. Niranjan, Rafeh, Nidal Abi, Burke, M. Nicholas, Sandoval, Yader B., and Brilakis, Emmanouil S.

Published
2024
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44. D-36 | Chronic Lung Disease in Chronic Total Occlusion Percutaneous Coronary Intervention

Author

Alexandrou, Michaella, Rempakos, Thanasis (Athanasios), Mutlu, Deniz, Al-Ogaili, Ahmed, Carvalho, Pedro E.P., Strepkos, Dimitrios, Choi, James W., Poommipanit, Paul, Alaswad, Khaldoon, Basir, Babar B., Davies, Rhian E., Jaffer, Farouc A., Dattilo, Philip, Azzalini, Lorenzo, Aygul, Nazif, Chandwaney, Raj H., Jefferson, Brian Keith, Görgülü, Şevket, Khatri, Jaikirshan, Young, Laura, Krestyaninov, Oleg, Khelimskii, Dmitrii, Frizzell, Jarrod, Göktekin, Ömer, Haddad, Elias Victor, Lee Kerrigan, Dr. Jimmy, Sadek Yass, Yasser Ahmed, Reddy, Niranjan K., Sr., Rafeh, Nidal Abi, Elbarouni, Basem, Rangan, Bavana V., Mastrodemos, Olga, Burke, M. Nicholas, Sandoval, Yader B., and Brilakis, Emmanouil S.

Published
2024
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45. Schistosoma mansoni infection alters the host pre-vaccination environment resulting in blunted Hepatitis B vaccination immune responses

Author

Muir, Roshell, primary, Metcalf, Talibah, additional, Fourati, Slim, additional, Bartsch, Yannic, additional, Kyosiimire-Lugemwa, Jacqueline, additional, Canderan, Glenda, additional, Alter, Galit, additional, Muyanja, Enoch, additional, Okech, Brenda, additional, Namatovu, Teddy, additional, Namara, Irene, additional, Namuniina, Annemarie, additional, Ssetaala, Ali, additional, Mpendo, Juliet, additional, Nanvubya, Annet, additional, Kitandwe, Paul Kato, additional, Bagaya, Bernard S., additional, Kiwanuka, Noah, additional, Nassuna, Jacent, additional, Biribawa, Victoria Menya, additional, Elliott, Alison M., additional, de Dood, Claudia J., additional, Senyonga, William, additional, Balungi, Priscilla, additional, Kaleebu, Pontiano, additional, Mayanja, Yunia, additional, Odongo, Matthew, additional, Connors, Jennifer, additional, Fast, Pat, additional, Price, Matt A., additional, Corstjens, Paul L. A. M., additional, van Dam, Govert J., additional, Kamali, Anatoli, additional, Sekaly, Rafick Pierre, additional, and Haddad, Elias K., additional

Published
2023
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48. Search for singly produced vector-like top partners in multilepton final states with 139 $\mathrm{fb}^{-1}$ of $pp$ collision data at $\sqrt{s} = 13$ TeV with the ATLAS detector

Author

Aad, Georges, Abbott, Braden Keim, Abeling, Kira, Abicht, Nils Julius, Abidi, Haider, Aboulhorma, Asmaa, Abramowicz, Halina, Abreu, Henso, Abulaiti, Yiming, Abusleme, Angel, Acharya, Bobby Samir, Adam Bourdarios, Claire, Adamczyk, Leszek, Adamek, Lukas, Addepalli, Sagar, Addison, Matt, Adelman, Jahred, Adiguzel, Aytul, Adye, Tim, Affolder, Tony, Afik, Yoav, Agaras, Merve Nazlim, Agarwala, Jinky, Aggarwal, Anamika, Agheorghiesei, Catalin, Ahmad, Ammara, Ahmadov, Faig, Ahmed, Waleed Syed, Ahuja, Sudha, Ai, Xiaocong, Aielli, Giulio, Ait Tamlihat, Malak, Aitbenchikh, Brahim, Aizenberg, Iakov, Akbiyik, Melike, Akesson, Torsten, Akimov, Andrei, Akiyama, Daiya, Akolkar, Nilima Nilesh, Al Khoury, Konie, Alberghi, Gian Luigi, Albert, Justin, Albicocco, Pietro, Albouy, Guillaume Lucas, Alderweireldt, Sara, Aleksa, Martin, Alexandrov, Igor, Alexa, Calin, Alexopoulos, Theodoros, Alfonsi, Alice, Alfonsi, Fabrizio, Algren, Malte, Alhroob, Muhammad, Ali, Babar, Ali, Hanadi, Ali, Shahzad, Alibocus, Samuel William, Aliev, Malik, Alimonti, Gianluca, Alkakhi, Wael, Allaire, Corentin, Allbrooke, Benedict, Allen, Julia Frances, Allendes Flores, Cristian Andres, Allport, Philip Patrick, Aloisio, Alberto, Alonso, Francisco, Alpigiani, Cristiano, Alvarez Estevez, Manuel, Alvarez Fernandez, Adrian, Alves Cardoso, Mario, Alviggi, Mariagrazia, Aly, Mohamed, Do Amaral Coutinho, Yara, Ambler, Alessandro, Amelung, Christoph, Amerl, Maximilian, Ames, Christoph, Amidei, Dante, Amor Dos Santos, Susana Patricia, Amos, Kieran Robert, Ananiev, Viktor, Anastopoulos, Christos, Andeen, Timothy Robert, Anders, John Kenneth, Andrean, Stefio Yosse, Andreazza, Attilio, Angelidakis, Stylianos, Angerami, Aaron, Anisenkov, Alexey, Annovi, Alberto, Antel, Claire, Anthony, Matthew Thomas, Antipov, Egor, Antonelli, Mario, Antrim, Daniel Joseph, Anulli, Fabio, Aoki, Masato, Aoki, Takumi, Aparisi Pozo, Javier Alberto, Aparo, Marco, Aperio Bella, Ludovica, Appelt, Christian, Apyan, Aram, Aranzabal Barrio, Nordin, Arcangeletti, Chiara, Arce, Ayana Tamu, Arena, Eloisa, Arguin, Jean-Francois, Argyropoulos, Spyros, Arling, Jan-Hendrik, Arnaez, Olivier, Arnold, Hannah, Arrubarrena Tame, Zulit Paola, Artoni, Giacomo, Asada, Haruka, Asai, Kanae, Asai, Shoji, Asbah, Nedaa Alexandra, Assahsah, Jihad, Assamagan, Ketevi Adikle, Astalos, Robert, Atashi, Rose, Atkin, Ryan Justin, Atkinson, Markus Julian, Atlay, Naim Bora, Atmani, Hicham, Atmasiddha, Prachi, Augsten, Kamil, Auricchio, Silvia, Auriol, Adrien, Austrup, Volker Andreas, Avolio, Giuseppe, Axiotis, Konstantinos, Azuelos, Georges, Babal, Dominik, Bachacou, Henri, Bachas, Konstantinos, Bachiu, Alexander, Backman, Karl Filip, Badea, Anthony, Bagnaia, Paolo, Bahmani, Marzieh, Bailey, Adam, Bailey, Virginia, Baines, John, Baines, Luke, Bakalis, Christos, Baker, Keith, Bakos, Evelin, Bakshi Gupta, Debottam, Balasubramanian, Rahul, Baldin, Evgenii, Balek, Petr, Ballabene, Eric, Balli, Fabrice, Baltes, Lisa Marie, Balunas, William Keaton, Balz, Johannes, Banas, Elzbieta, Bandieramonte, Marilena, Bandyopadhyay, Anjishnu, Bansal, Shubham, Barak, Liron, Barakat, Marawan, Barberio, Elisabetta, Barberis, Dario, Barbero, Marlon Benoit, Barbour, Gregory, Barends, Kevin Nicholas, Barillari, Teresa, Barisits, Martin, Barklow, Tim, Baron, Petr, Baron, Diego, Baroncelli, Toni, Barone, Gaetano, Barr, Alan, Barr, Jackson, Barranco Navarro, Laura, Barreiro Alonso, Fernando, Barreiro Guimaraes Da Costa, Joao, Barron, Uriel, Barros, Maura, Barsov, Sergey, Bartels, Falk, Bartoldus, Rainer, Barton, Adam Edward, Bartos, Pavol, Basan, Alexander, Baselga Bacardit, Marta, Bassalat, Ahmed, Basso, Matthew Joseph, Basson, Candice Ruth, Bates, Richard, Batlamous, Souad, Batley, Richard, Batool, Binish, Battaglia, Marco, Battulga, Daariimaa, Bauce, Matteo, Bauer, Michael, Bauer, Patrick, Bazzano, Tomas, Beacham, James, Beau, Tristan, Beauchemin, Pierre-Hugues, Becherer, Fabian, Bechtle, Philip, Beck, Hans Peter, Becker, Kathrin, Beddall, Andrew, Bednyakov, Vadim, Bee, Chris, Beemster, Lars, Beermann, Thomas, Begalli, Marcia, Begel, Michael, Behera, Arabinda, Behr, Janna Katharina, Beirer, Joshua Falco, Beisiegel, Florian, Belfkir, Mohamed, Bella, Gideon, Bellagamba, Lorenzo, Bellerive, Alain, Bellos, Panagiotis, Beloborodov, Konstantin, Belyaev, Nikita, Benchekroun, Driss, Bendebba, Fatima, Benhammou, Yan, Benoit, Mathieu, Bensinger, Jim, Bentvelsen, Stan, Beresford, Lydia Audrey, Beretta, Matteo Mario, Bergeaas Kuutmann, Elin, Berger, Nicolas, Bergmann, Benedikt Ludwig, Beringer, Juerg, Bernardi, Gregorio, Bernius, Catrin, Bernlochner, Florian Urs, Bernon, Florent, Berry, Tracey, Berta, Peter, Berthold, Anne-Sophie, Bertram, Iain, Bethke, Siegfried, Betti, Alessandra, Bevan, Adrian, Bhamjee, Muaaz, Bhatta, Somadutta, Bhattacharya, Deb Sankar, Bhattarai, Prajita, Bhopatkar, Vallary Shashikant, Bi, Ran, Bianchi, Riccardo Maria, Bianco, Gianluca, Biebel, Otmar, Bielski, Rafal, Biglietti, Michela, Billoud, Thomas, Bindi, Marcello, Bingul, Ahmet, Bini, Cesare, Biondini, Alessandro, Birch-Sykes, Callum Jacob, Bird, Gareth Adam, Birman, Mattias, Biros, Marek, Bisanz, Tobias, Bisceglie, Emanuele, Biswas, Diptaparna, Bitadze, Alexander, Bjoerke, Kristian, Bloch, Ingo, Blocker, Craig, Blue, Andrew James, Blumenschein, Ulla, Blumenthal, Julian, Bobbink, Gerjan, Bobrovnikov, Viktor, Boehler, Michael, Bohm, Burkhard, Bogavac, Danijela, Bogdanchikov, Alexander, Bohm, Christian, Boisvert, Veronique, Bokan, Petar, Bold, Tomasz, Bomben, Marco, Bona, Marcella, Boonekamp, Maarten, Booth, Callum Dale, Borbely, Albert Gyorgy, Bordulev, Iurii, Borecka-Bielska, Hanna Maria, Borgna, Lucas Santiago, Borissov, Guennadi, Bortoletto, Daniela, Boscherini, Davide, Fernandez-Bosman, Martine, Bossio, Jonathan, Bouaouda, Khalil, Bouchhar, Naseem, Boudreau, Joseph, Bouhova-Thacker, Eva, Boumediene, Djamel Eddine, Bouquet, Romain, Boveia, Antonio, Boyd, Jamie, Boye, Diallo, Boyko, Igor, Bracinik, Juraj, Brahimi, Nihal, Brandt, Gerhard Immanuel, Brandt, Oleg, Braren, Frued Erik, Brau, Benjamin Paul, Brau, Jim, Schimmel Brener, Roy, Brenner, Lydia, Brenner, Richard, Bressler, Shikma, Britton, David, Britzger, Daniel Andreas, Brock, Ian, Brooijmans, Gustaaf, Brooks, William King, Brost, Elizabeth, Brown, Leesa Marea, Bruce, Laura Elaine, Bruckler, Tim Lukas, Bruckman De Renstrom, Pawel, Bruers, Ben, Bruncko, Dusan, Bruni, Alessia, Bruni, Graziano, Bruschi, Marco, Bruscino, Nello, Buanes, Trygve, Buat, Quentin, Buchin, Daniel, Buckley, Andy, Bugge, Magnar Kopangen, Bulekov, Oleg, Bullard, Brendon, Burdin, Sergey, Burgard, Carsten, Burger, Angela Maria, Burghgrave, Blake Oliver, Burlayenko, Oleksandr, Burr, Jon, Burton, Charles, Burzynski, Jackson Carl, Busch, Elena Laura, Buescher, Volker, Bussey, Peter John, Butler, John Mark, Buttar, Craig Macleod, Butterworth, Jonathan, Buttinger, Will, Buxo Vazquez, Carlos Josue, Buzykaev, Alexey, Cabras, Grazia, Cabrera Urban, Susana, Cadamuro, Luca, Caforio, Davide, Cai, Huacheng, Cai, Yuchen, Cairo, Valentina, Cakir, Orhan, Calace, Noemi, Calafiura, Paolo, Calderini, Giovanni, Calfayan, Philippe, Callea, Giuseppe, Caloba, Luiz, Calvet, David, Calvet, Samuel, Calvet, Thomas Philippe, Calvetti, Milene, Camacho Toro, Reina Coromoto, Camarda, Stefano, Camarero Munoz, Daniel, Camarri, Paolo, Camerlingo, Maria Teresa, Cameron, David, Camincher, Clement, Campanelli, Mario, Camplani, Alessandra, Canale, Vincenzo, Canesse, Auriane, Bret Cano, Marc, Cantero Garcia, Josu, Cao, Yumeng, Capocasa, Francesca, Capua, Marcella, Carbone, Antonio, Cardarelli, Roberto, Cardenas, Juan Carlos, Jr., Cardillo, Fabio, Carli, Tancredi, Carlino, Giampaolo, Carlotto, Juan Ignacio, Carlson, Ben, Carlson, Evan Michael, Carminati, Leonardo, Carnelli, Alberto, Carnesale, Maria, Caron, Sascha, Carquin Lopez, Edson, Carra, Sonia, Carratta, Giuseppe, Carrio Argos, Fernando, Carter, Joseph, Carter, Thomas Michael, Casado Lechuga, Pilar, Caspar, Maximilian, Castiglia, Emma Grace, Castillo, Florencia Luciana, Castillo Garcia, Lucia, Castillo Gimenez, Victoria, Castro, Nuno, Catinaccio, Andrea, Catmore, James, Cavaliere, Viviana, Cavalli, Noemi, Cavasinni, Vincenzo, Cekmecelioglu, Yusuf Can, Celebi, Emre, Celli, Federico, Centonze, Martino Salomone, Cerny, Karel, Santiago Cerqueira, Augusto, Cerri, Alex, Cerrito, Lucio, Cerutti, Fabio, Cervato, Beatrice, Cervelli, Alberto, Cesarini, Gianmario, Cetin, Serkant, Chadi, Zakaria, Chakraborty, Dhiman, Chala, Mikael, Chan, Jay, Chan, Wai Yuen, Chapman, John Derek, Chapon, Emilien, Chargeishvili, Bakar, Charlton, Dave, Charman, Thomas Paul, Chatterjee, Meghranjana, Chauhan, Chainika, Chekanov, Sergei, Chekulaev, Sergey, Shelkov, G., Chen, Andy, Chen, Boping, Chen, Charlie, Chen, Huirun, Chen, Hucheng, Chen, Jing, Chen, Jiayi, Chen, Maggie, Chen, Shion, Chen, Shenjian, Chen, Xiang, Chen, Xin, Chen, Ye, Cheng, Alkaid, Cheng, Hok Chuen Tom, Cheong, Sanha, Cheplakov, Alexander, Cheremushkina, Evgeniya, Cherepanova, Elizaveta, Cherkaoui, Rajaa, Cheu, Elliott, Cheung, Kingman, Chevalier, Laurent, Chiarella, Vitaliano, Chiarelli, Giorgio, Chiedde, Nemer, Chiodini, Gabriele, Chisholm, Andrew Stephen, Chitan, Adrian, Chitishvili, Mariam, Chizhov, Mihail, Choi, Kyungeon, Chomont, Arthur, Chou, Yuan-Tang, Chow, Edwin, Chowdhury, Tasnuva, Chu, Michael Kwok Lam, Chu, Ming Chung, Chu, Xiaotong, Chudoba, Jiri, Chwastowski, Janusz, Cieri, Davide, Ciesla, Krzysztof, Cindro, Vladimir, Ciocio, Alessandra, Cirotto, Francesco, Citron, Zvi, Citterio, Mauro, Ciubotaru, Dan Andrei, Ciungu, Bianca Monica, Clark, Allan, Clark, Philip, Clavijo Columbie, Jose Manuel, Clawson, Savannah, Clement, Christophe, Clercx, Joshua, Clissa, Luca, Coadou, Yann, Cobal, Marina, Coccaro, Andrea, Barrue, Ricardo, Coelho Lopes De Sa, Rafael, Coelli, Simone, Cohen, Hadar, Coimbra, Artur, Cole, Brian, Collot, Johann, Conde Muino, Patricia, Connell, Matt, Connell, Simon, Connelly, Ian Allan, Conroy, Eimear Isobel, Conventi, Francesco, Cooke, Harry, Sarkar, Amanda, Cordeiro Oudot Choi, Artur, Cormier, Felix, Corpe, Louie Dartmoor, Corradi, Massimo, Corriveau, Francois, Cortes Gonzalez, Arely, Costa Mezquita, Maria Jose, Costanza, Francesco, Costanzo, Davide, Cote, Benjamin, Cowan, Glen, Cranmer, Kyle Stuart, Cremonini, Davide, Crepe-Renaudin, Sabine, Crescioli, Francesco, Cristinziani, Markus, Cristoforetti, Marco, Croft, Vincent Alexander, Crosby, Jacob Edwin, Crosetti, Nanni, Cueto Gomez, Ana Rosario, Cuhadar Donszelmann, Tulay, Cui, Han, Cui, Zhaoyuan, Cunningham, Liam, Curcio, Francesco, Czodrowski, Patrick Karl, Czurylo, Marta, Sousa, Mario Jose, Da Fonseca Pinto, Joao Victor, Da Via, Cinzia, Dabrowski, Wladyslaw, Dado, Tomas, Dahbi, Salah-Eddine, Dai, Tiesheng, Dallapiccola, Carlo, Dam, Mogens, D'Amen, Gabriele, D'Amico, Valerio, Damp, Johannes Frederic, Dandoy, Jeff, Daneri, Maria Florencia, Danninger, Matthias, Dao, Valerio, Darbo, Nanni, Darmora, Smita, Das, Sruthy Jyothi, D'Auria, Saverio, David, Claire, Davidek, Tomas, Davis-Purcell, Benjamin Richard, Dawson, Ian, Day-Hall, Henry, De, Kaushik, De Asmundis, Riccardo, De Biase, Nicola, De Castro, Stefano, De Groot, Nicolo, De Jong, Paul, De La Torre Perez, Hector, De Maria, Antonio, De Salvo, Alessandro, De Sanctis, Umberto, De Santo, Antonella, De Vivie De Regie, Jean-Baptiste, Dedovich, Dmitri, Degens, Jordy, Deiana, Allison Mccarn, Del Corso, Francesca, Del Peso, Jose, Del Rio, Fer, Deliot, Frederic, Delitzsch, Chris Malena, Della Pietra, Massimo, Della Volpe, Domenico, Dell'Acqua, Andrea, Dell'Asta, Lidia, Delmastro, Marco, Delsart, Pierre Antoine, Demers Konezny, Sarah Marie, Demichev, Mikhail, Denisov, Serguei, D'Eramo, Louis, Derendarz, Dominik Karol, Derue, Frederic, Dervan, Paul, Desch, Klaus, Deutsch, Christopher, Di Bello, Francesco Armando, Di Ciaccio, Anna, Di Ciaccio, Lucia, Di Domenico, Antonio, Di Donato, Camilla, Di Girolamo, Alessandro, Di Gregorio, Giulia, Di Luca, Andrea, Di Micco, Biagio, Di Nardo, Roberto, Diaconu, Cristinel, Diamantopoulou, Magda, De Almeida Dias, Flavia, Vale, Tiago, Diaz Gutierrez, Marco Aurelio, Diaz Capriles, Federico Guillermo, Didenko, Mariia, Diehl, Edward, Diehl, Leena, Diez Cornell, Sergio, Diez Pardos, Carmen, Dimitriadi, Christina, Dimitrievska, Aleksandra, Dingfelder, Jochen Christian, Dinu, Ioan-Mihail, Dittmeier, Sebastian, Dittus, Fido, Djama, Fares, Djobava, Tamar, Djuvsland, Julia Isabell, Doglioni, Caterina, Dolejsi, Jiri, Dolezal, Zdenek, Donadelli, Marisilvia, Dong, Binbin, Donini, Julien Noce, D'Onofrio, Adelina, D'Onofrio, Monica, Dopke, Jens, Doria, Alessandra, Dos Santos Fernandes, Nuno, Dova, Maria Teresa, Doyle, Tony, Draguet, Maxence, Dreyer, Etienne, Drivas-Koulouris, Ioannis, Drobac, Alec Swenson, Drozdova, Mariia, Du, Dongshuo, Du Pree, Tristan Arnoldus, Dubinin, Filipp, Dubovsky, Michal, Duchovni, Ehud, Duckeck, Guenter, Ducu, Otilia Anamaria, Duda, Dominik, Dudarev, Alexey, Duden, Emily Rose, D'Uffizi, Matteo, Duflot, Laurent, Duehrssen-Debling, Michael, Dulsen, Carsten, Dumitriu, Ana Elena, Dunford, Monica, Dungs, Sascha, Dunne, Katherine Elaine, Duperrin, Arnaud, Yildiz, Hatice, Dueren, Michael Johannes, Durglishvili, Archil, Dwyer, Brianna, Dyckes, Ian, Dyndal, Mateusz, Dysch, Samuel Dezso, Dziedzic, Bartosz Sebastian, Earnshaw, Zoe Olivia, Eberwein, Gregor Hieronymus, Eckerova, Barbora, Eggebrecht, Stephen, Eggleston, Michael Glenn, Purcino De Souza, Edmar Egidio, Ehrke, Lukas, Eigen, Gerald, Einsweiler, Kevin Frank, Ekelof, Tord Johan Carl, Ekman, Per Alexander, El Farkh, Saad, El Ghazali, Yassine, El Jarrari, Hassnae, El Moussaouy, Ali, Ellajosyula, Venugopal, Ellert, Mattias, Ellinghaus, Frank, Elliot, Alison, Ellis, Nick, Elmsheuser, Johannes, Elsing, Markus, Emeliyanov, Dmitry, Enari, Yuji, Ene, Irina, Epari, Shalini, Erdmann, Johannes, Erland, Paula Agnieszka, Errenst, Martin, Escalier, Marc, Escobar Ibanez, Carlos, Etzion, Erez, Gaspar De Andrade Evans, Guiomar, Evans, Hal, Evans, Levi, Evans, Meirin Oan, Ezhilov, Aleksei, Ezzarqtouni, Sanae, Fabbri, Federica, Fabbri, Laura, Facini, Gabriel, Fadeyev, Vitaliy, Fakhrutdinov, Rinat, Falciano, Speranza, Falda Coelho, Luis, Falke, Peter Johannes, Faltova, Jana, Fan, Cunwei, Fan, Yunyun, Fang, Yaquan, Fanti, Marcello, Faraj, Mohammed, Farazpay, Zahra, Farbin, Amir, Farilla, Ada, Farooque, Trisha, Farrington, Sinead, Fassi, Farida, Fassouliotis, Dimitris, Faucci Giannelli, Michele, Fawcett, William James, Fayard, Louis, Federic, Pavol, Federicova, Pavla, Fedin, Oleg, Fedotov, Gleb, Feickert, Matthew, Feligioni, Lorenzo, Fellers, Deion Elgin, Feng, Cunfeng, Feng, Minyu, Feng, Zhuoran, Fenton, Michael James, Fenyuk, Alexandre, Ferencz, Lars, Ferguson, Ruby Alice Molly, Fernandez Luengo, Sergio Ivan, Fernoux, Maxime, Ferrando, James, Ferrari, Arnaud, Ferrari, Pamela, Ferrari, Roberto, Ferrere, Didier, Ferretti, Claudio, Fiedler, Frank, Filipcic, Andrej, Filmer, Emily, Filthaut, Frank, Castro Nunes Fiolhais, Miguel, Fiorini, Luca, Fisher, Wade Cameron, Fitschen, Tobias, Fitzhugh, Peter Michael, Fleck, Ivor, Fleischmann, Philipp, Flick, Tobias, Flores, Lucas Macrorie, Flores, Marvin, Flores Castillo, Luis Roberto, Flores Sanz De Acedo, Leyre, Follega, Francesco Maria, Fomin, Nikolai, Foo, Joel Hengwei, Forland, Blake Christopher, Formica, Andrea, Forti, Alessandra, Fortin, Etienne Marie, Fortman, Anne Winifred, Foti, Maria Giovanna, Fountas, Leonidas, Fournier, Daniel, Fox, Harald, Francavilla, Paolo, Francescato, Simone, Franchellucci, Stefano, Franchini, Matteo, Franchino, Silvia, Francis, David, Franco, Luca, Franconi, Laura, Franklin, Melissa, Frattari, Guglielmo, Freegard, Arran Charles, Spolidoro Freund, Werner, Frid, Yuval Yitzhak, Fritzsche, Nick, Froch, Alexander, Froidevaux, Daniel, Frost, James, Fu, Yao, Fujimoto, Minori, Fullana Torregrosa, Esteban, Fung, Kin Yip, Simas Filho, Eduardo Furtado De, Furukawa, Marin, Fuster Verdu, Juan, Gabrielli, Alessandro, Gabrielli, Andrea, Gadow, Philipp, Gagliardi, Guido, Gagnon, Louis-Guillaume, Gallas, 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Gil, Damian Tomasz, Gilbert, Alexander Kevin, Gilbert, Benjamin Jacob, Gillberg, Dag, Gilles, Geoffrey, Gillwald, Nils, Ginabat, Louis, Gingrich, Doug, Giordani, Mapo, Giraud, Pierre-Francois, Giugliarelli, Gilberto, Giugni, Danilo, Giuli, Francesco, Gkialas, Ioannis, Gladilin, Leonid, Glasman, Claudia, Gledhill, Galen Rhodes, Glemza, Gediminas, Glisic, Marija, Gnesi, Ivan, Go, Yeonju, Goblirsch-Kolb, Maximilian Emanuel, Gocke, Benedikt, Godin, Dominique, Gokturk, Berare, Goldfarb, Steven, Golling, Tobias, Gololo, Mpho Gift Doctor, Golubkov, Dmitry, Gombas, Jason Peter, Da Silva Gomes, Agostinho, Gomes, Gabriel, Gomez Delegido, Antonio Jesus, Morais Silva Goncalo, Ricardo Jose, Gonella, Giulia, Gonella, Laura, Gongadze, Alexi, Gonnella, Francesco, Gonski, Julia Lynne, Gonzalez, Richards, Gonzalez De La Hoz, Santiago, Gonzalez Fernandez, Sergio, Gonzalez Lopez, Ricardo, Gonzalez Renteria, Cesar, Gonzalez Suarez, Rebeca, Gonzalez Sevilla, Sergio, Gonzalvo Rodriguez, Galo Rafael, 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Giuliano, Guth, Manuel, Gutierrez, Phillip, Gutierrez Zagazeta, Luis Felipe, Gutschow, Christian, Gwenlan, Claire, Gwilliam, Carl, Haaland, Even Simonsen, Haas, Andrew, Habedank, Martin, Haber, Carl, Hadavand, Haleh, Hadef, Asma, Hadzic, Sejla, Hahn, Jan Joachim, Haines, Emil, Haleem, Mahsana, Haley, Joseph, Hall, Jack Joseph, Hallewell, Gregory, Halser, Lea, Hamano, Kenji, Hamdaoui, Hassane, Hamer, Matthias, Hamity, Guillermo Nicolas, Hampshire, Emily Jane, Han, Jingyi, Han, Kunlin, Han, Liangliang, Han, Liang, Han, Shuo, Han, Yi Fei, Hanagaki, Kazunori, Hance, Mike, Hangal, Dhanush Anil, Hanif, Hamza, Hank, Michael Donald, Hankache, Robert, Hansen, Jorgen Beck, Hansen, Dines, Hansen, Peter, Hara, Kazuhiko, Harada, Daigo, Harenberg, Torsten, Harkusha, Siarhei, Harris, Matthew Leary, Harris, Ynyr, Harrison, Jack, Harrison, Natalie, Harrison, Paul Fraser, Hartman, Nicole Michelle, Hartmann, Nikolai, Hasegawa, Yoji, Hasib, Ahmed, Haug, Sigve, Hauser, Reiner, Hawkes, Chris, Hawkings, Richard, Hayashi, Yuichiro, Hayashida, Shota, Hayden, Daniel, Hayes, Christopher Robyn, Hayes, Robin, Hays, Chris, Hays, Jonathan, Hayward, Helen, He, Fudong, He, Mingxu, He, Yunjian, He, Yajun, Heatley, Nathan Barry, Hedberg, Vincent, Heggelund, Andreas Lokken, Hehir, Natasha, Heidegger, Constantin, Heidegger, Kim Katrin, Heidorn, William Dale, Heilman, Jesse, Heim, Sarah, Heim, Timon, Heinlein, James Geddy, Heinrich, Jochen Jens, Heinrich, Lukas Alexander, Hejbal, Jiri, Helary, Louis, Held, Alexander, Hellesund, Simen, Helling, Cole Michael, Hellman, Sten, Henderson, Robert, Henkelmann, Lars, Henriques Correia, Ana Maria, Herde, Hannah Elizabeth, Hernandez Jimenez, Yesenia, Herrmann, Lena Maria, Herrmann, Tim, Herten, Gregor, Hertenberger, Ralf, Hervas, Luis, Hesping, Moritz, Hessey, Nigel, Hibi, Hiroaki, Hillier, Stephen, Hinds, Julia Rose, Hinterkeuser, Florian, Hirose, Minoru, Hirose, Shigeki, Hirschbuehl, Dominic, Hitchings, Thomas Glyn, Hiti, Bojan, Hobbs, John David, Hobincu, Radu, Tal Hod, Noam, Hodgkinson, Mark, Hodkinson, Benjamin Haslum, Hoecker, Andreas, Hofer, Judith, Holm, Tanja, Holzbock, Michael, Hommels, Bart, Honan, Benjamin Paul, Hong, Jiangliu, Hong, Tae Min, Hooberman, Benjamin Henry, Hopkins, Walter, Horii, Yasuyuki, Hou, Suen, Howard, Alissa Shirley-Ann, Howarth, James William, Hoya, Joaquin, Hrabovsky, Miroslav, Hrynevich, Aliaksei, Hrynova, Tetiana, Hsu, Pai-Hsien, Hsu, Shih-Chieh, Hu, Qipeng, Hu, Yifan, Huang, Shuhui, Huang, Xiaozhong, Huang, Yicong, Huang, Yanping, Huang, Zuchen, Hubacek, Zdenek, Hubner, Michael, Huegging, Fabian, Huffman, Todd Brian, Hugli, Cedrine Alexandra, Huhtinen, Mika, Huiberts, Simon Kristian, Hulsken, Raphael Alain, Huseynov, Nazim, Huston, Joey, Huth, John, Hyneman, Rachel Jordan, Iacobucci, Giuseppe, Iakovidis, George, Ibragimov, Iskander, Iconomidou-Fayard, Lydia, Iengo, Paolo, Iguchi, Ryunosuke, Iizawa, Tomoya, Ikegami, Yoichi, Ilic, Nikolina, Imam, Hajar, Ince Lezki, Merve, Ingebretsen Carlson, Tom, Introzzi, Gianluca, Iodice, Mauro, Ippolito, Valerio, Irwin, Rebecca Katie, Ishino, Masaya, Islam, Wasikul, Issever, Cigdem, Istin, Serhat, Ito, Hiroki, Iturbe, Julia, Iuppa, Roberto, Ivina, Anna, Izen, Joseph Michael, Izzo, Vincenzo, Jacka, Petr, Jackson, Paul, Jacobs, Ruth Magdalena, Jaeger, Benjamin Paul, Jagfeld, Christoph, Jain, Prasham, Jakel, Gunnar, Jakobs, Karl, Jakoubek, Tomas, Jamieson, Jonathan, Janas, Krzysztof, Jaspan, Adam Elliott, Javurkova, Martina, Jeanneau, Fabien, Jeanty, Laura, Jejelava, Juansher, Jenni, Peter, Jessiman, Callan, Jezequel, Stephane, Jia, Chen, Jia, Jiangyong, Jia, Xiaohe, Jia, Xuewei, Jia, Zihang, Jiang, Yi, Jiggins, Stephen, Jimenez Pena, Javier, Jin, Shan, Jinaru, Adam, Jinnouchi, Osamu, Johansson, Per Daniel Conny, Johns, Kenneth, Johnson, Jacob Wayne, Jones, Dominic, Jones, Eleanor, Jones, Paul, Jones, Roger, Jones, Tim, Joshi, Roshan, Jovicevic, Jelena, Ju, Xiangyang, Junggeburth, Johannes, Junkermann, Thomas, Juste Rozas, Aurelio, Juzek, Monika Katarzyna, Kabana, Sonia, Kaczmarska, Anna, Kado, Marumi, Kagan, Harris, Kagan, Michael, Kahn, Alan Mathew, Kahn, Abraham, Kahra, Christian, Kaji, Toshiaki, Kajomovitz Must, Enrique, Kakati, Nilotpal, Kalaitzidou, Ilia, Kalderon, Will, Kamenshchikov, Andrey, Kanayama, Shuhei, Kang, Nathan Jihoon, Kar, Deepak, Karava, Kla, Kareem, Mohammad, Karentzos, Efstathios, Karkanias, Ioannis, Karkout, Osama, Karpov, Sergey, Karpova, Zoya, Kartvelishvili, Vato, Karyukhin, Andrey, Kasimi, Eirini, Katzy, Judith, Kaur, Sandeep, Kawade, Kentaro, Kawale, Mayuri Prabhakar, Kawamoto, Tatsuo, Kay, Ellis, Kaya, Colette, Kazakos, Stergios, Kazanin, Vassili, Ke, Yan, Keaveney, James Michael, Keeler, Richard, Kehris, Gustavs, Keller, John Stakely, Kelly, Aidan Sean, Kempster, Jacob Julian, Kennedy, Kiley Elizabeth, Kennedy, Philip David, Kepka, Oldrich, Kerridge, Benjamin Philip, Kersten, Susanne, Kersevan, Borut Paul, Keshri, Sumit, Keszeghova, Lucia, Ketabchi, Sana, Khandoga, Mykola, Khanov, Alexander, Kharlamov, Alexey, Kharlamova, Tatyana, Khoda, Elham E., Khoo, Teng Jian, Khoriauli, Gia, Khubua, Djemal, Khwaira, Yahya A.R., Kilgallon, Aaron Joseph, Kim, Dongwon, Kim, Young-Kee, Kimura, Naoki, Kirchhoff, Andreas, Kirfel, Christian, Kirfel, Florian, Kirk, Julie, Kiryunin, Andrei, Kitsaki, Chara, Kivernyk, Oleh, Klassen, Martin, Klein, Christoph Thomas, Klein, Lucas, Klein, Matthew Henry, Klein, Max, Klein, Samuel Byrne, Klein, Uta, Klimek, Pawel Jan, Klimentov, Alexei, Klioutchnikova, Tatiana, Kluit, Peter, Kluth, Stefan, Kneringer, Emmerich, Knight, Timothy Michael, Knue, Andrea Helen, Kobayashi, Ren, Koch, Simon Florian, Kocian, Martin, Kodys, Peter, Kock, Daniela, Konig, Philipp, Koffas, Thomas, Kolb, Mathis, Koletsou, Iro, Komarek, Tomas, Koeneke, Karsten, Kong, Albert, Kono, Takanori, Konstantinidis, Nikolaos, Konya, Balazs, Kopeliansky, Revital, Koperny, Stefan Zenon, Korcyl, Krzysztof Marian, Kordas, Kostas, Koren, Guy, Korn, Andreas, Korn, Steffen, Korolkov, Ilya, 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Chilufya, Myagkov, Alexei, Myers, Andrew Joel, Myers, Ava Anne, Myers, Greg, Myska, Miroslav, Nachman, Ben, Nackenhorst, Olaf, Nag, Abhishek, Nagai, Koichi, Nagano, Kunihiro, Nagle, James Lawrence, Nagy, Elemer, Nairz, Armin, Nakahama Higuchi, Yu, Nakamura, Koji, Nakkalil, Keerthi, Nanjo, Hajime, Narayan, Rohin Thampilali, Narayanan, Easwar Anand, Naryshkin, Iurii, Naseri, Mohsen, Nasri, Salah, Nass, Christian, Navarro, Gabriela Alejandra, Navarro Gonzalez, Josep, Nayak, Ranjit, Nayaz, Ab, Nechaeva, Polina, Nechansky, Filip, Nedic, Luka, Neep, Tom, Negri, Andrea, Negrini, Matteo, Nellist, Clara, Nelson, Christina, Nelson, Kevin Michael, Nemecek, Stanislav, Nessi, Marzio, Neubauer, Mark, Neuhaus, Friedemann, Neundorf, Jonas, Newhouse, Robin, Newman, Paul Richard, Ng, Chi Wing, Ng, Ying Wun Yvonne, Ngair, Badr-Eddine, Nguyen, Hoang Dai Nghia, Nickerson, Richard, Nikolaidou, Rosy, Nielsen, Jason, Niemeyer, Marcel, Niermann, Joana, Nikiforou, Nikiforos, Nikolaenko, Vladimir, Nikolic, 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Jose Gabriel, Reynolds, Bryan, Reynolds, Elliot, Rezanova, Olga, Reznicek, Pavel, Ribaric, Neza, Ricci, Ester, Richter, Robert, Richter, Stefan, Richter-Was, Elzbieta, Ridel, Melissa, Ridouani, Selaiman, Rieck, Patrick, Riedler, Petra, Rijssenbeek, Michael, Rimoldi, Adele, Rimoldi, Marco, Rinaldi, Lorenzo, Rinn, Timothy Thomas, Rinnagel, Maximilian Paul, Ripellino, Giulia, Riu, Imma, Rivadeneira Bracho, Pablo Andres, Rivera Vergara, Juan Cristobal, Rizatdinova, Flera, Rizvi, Eram Syed, Roberts, Bryn Arthur, Roberts, Ryan, Robertson, Steven, Robin, Matthieu, Robinson, Dave, Robles Gajardo, Carolina Michel, Robles Manzano, Marisol, Robson, Aidan, Rocchi, Alessandro, Roda, Chiara, Rodriguez Bosca, Sergi, Rodriguez Garcia, Yohany, Rodriguez Rodriguez, Arturo, Rodriguez Vera, Ana Maria, Roe, Shaun, Roemer, Jonas Till, Roepe-Gier, Amber, Roggel, Jens, Rohne, Ole, Rojas Caballero, Rimsky Alejandro, Roland, Christophe Pol A., Roloff, Jennifer, Romaniouk, Anatoli, Romano, Emanuele, Romano, Marino, Romero, Anabel, Rompotis, Nikolaos, Roos, Lydia, Rosati, Stefano, Rosser, Benjamin John, Rossi, Eleonora, Rossi, Elvira, Rossi, Leonardo, Rossini, Lorenzo, Rosten, Rachel Christine, Rotaru, Marina, Rottler, Benjamin, Rougier, Charline, Rousseau, David, Rousso, David, Roy, Avik, Roy-Garand, Sebastien, Rozanov, Alexandre, Rozen, Yoram, Ruan, Ruanxf, Rubio Jimenez, Adrian, Ruby, Adam James, Ruelas Rivera, Victor Hugo, Ruggeri, Tristan Andrew, Ruggiero, Alessandro, Ruiz Martinez, Arantxa, Rummler, Andre, Rurikova, Zuzana, Rusakovich, Nikolai, Russell, Heather, Russo, Graziella, Rutherfoord, John P., Rutherford Colmenares, Sebastian, Rybacki, Katherine Amy, Rybar, Martin, Rye, Eli Baverfjord, Ryzhov, Andrey, Sabater Iglesias, Jorge Andres, Sabatini, Paolo, Sabetta, Luigi, Sadrozinski, Hartmut, Safai Tehrani, Francesco, Safarzadeh Samani, Batool, Safdari, Murtaza, Saha, Shreya, Sahinsoy, Merve, Saimpert, Matthias, Saito, Masahiko, Saito, Tomoyuki, Salamani, Dalila, Salnikov, Andy, Salt, Jose, Salvador Salas, Adrian, Salvatore, Daniela, Salvatore, Fabrizio, Salzburger, Andreas, Sammel, Dirk, Sampsonidis, Dimos, Sampsonidou, Despoina, Sanchez Martinez, Francisco Javier, Sanchez Pineda, Arturos, Sanchez Sebastian, Victoria, Sandaker, Heidi, Sander, Christian, Sandesara, Jay Ajitbhai, Sandhoff, Marisa, Sandoval Usme, Carlos, Sankey, David, Sano, Takane, Sansoni, Andrea, Santi, Lorenzo, Santoni, Claudio, Santos, Helena, Santpur, Sai Neha, Santra, Arka, Saoucha, Kamal, Mendes Saraiva, Joao Gentil, Sardain, Jad Mathieu, Sasaki, Osamu, Sato, Koji, Sauer, Christof, Sauerburger, Frank, Sauvan, Emmanuel, Savard, Pierre, Sawada, Ryu, Sawyer, Craig, Sawyer, Lee, Sayago Galvan, Ivan, Sbarra, Carla, Sbrizzi, Antonio, Scanlon, Timothy Paul, Schaarschmidt, Jana, Schacht, Peter, Schaefer, Douglas Michael, Schaefer, Uli, Schaffer, R.D., Schaile, Dorothee, Schamberger, Robert Dean, Jr., Scharf, Christian, Schefer, Meinrad Moritz, Chtcheguelski, Valery, Scheirich, Daniel, Schenck, Ferdinand, Schernau, Michael, Scheulen, Chris, Schiavi, Carlo, Schioppa, Enrico, Junior., Schioppa, Marco, Schlag, Bastian, Schleicher, Katharina, Schlenker, Stefan, Schmeing, Jonas, Schmidt, Mustafa Andre, Schmieden, Kristof, Schmitt, Christian, Schmitt, Stefan, Schoeffel, Laurent Olivier, Schoening, Andre, Scholer, Patrick, Schopf, Elisabeth, Schott, Matthias, Schovancova, Jaroslava, Schramm, Steven, Schroeder, Frederic, Schroer, Tomke, Schultz-Coulon, Hans-Christian, Schumacher, Markus, Schumm, Bruce Andrew, Schune, Philippe, Schuy, Alexander Joseph, Schwartz, Hava Rhian, Schwartzman, Ariel Gustavo, Schwarz, Thomas Andrew, Schwemling, Philippe, Schwienhorst, Reinhard, Sciandra, Andrea, Sciolla, Gabriella, Scuri, Fabrizio, Sebastiani, Cristiano, Sedlaczek, Kevin, Seema, Pienpen, Seidel, Sally, Seiden, Abraham, Seidlitz, Blair Daniel, Seitz, Claudia, Seixas, Jose, Sekhniaidze, Givi, Sekula, Stephen Jacob, Selem, Luka, Semprini Cesari, Nicola, Sengupta, Debajyoti, Senthilkumar, Varsha, Serin, Laurent, Serkin, Leonid, Sessa, Marco, Severini, Horst, Sforza, Federico, Sfyrla, Anna, Shabalina, Elizaveta, Shaheen, Rabia, Shahinian, Jeff, Shaked Renous, Dan, Shan, Lianyou, Shapiro, Marjorie, Sharma, Abhishek, Sharma, Punit, Sharma, Surabhi, Shatalov, Sppavel, Shaw, Kate, Shaw, Savanna, Kirianova, Anna, Shen, Qiuping, Sherwood, Peter, Shi, Liaoshan, Shi, Xin, Shimmin, Chase Owen, Shimogama, Yoshihiro, Shinner, James David, Shipsey, Ian, Shirabe, Shohei, Shiyakova, Mariya, Shlomi, Jonathan, Shochet, Mel, Shojaii, Seyed Ruhollah, Shope, David Richard, Shrestha, Bijay, Shrestha, Suyog, Shrif, Esra Mohammed, Shroff, Maheyer Jamshed, Sicho, Petr, Sickles, Anne Marie, Sideras Haddad, Elias, Sidoti, Antonio, Siegert, Frank, Sijacki, Dorde, Sikora, Rafal, Sili, Francisco, Cardoso Silva, Julia Manuela, Silva Oliveira, Marcos Vinicius, Silverstein, Samuel, Simion, Stefan, Simoniello, Rosa, Simpson, Ethan Lewis, Simpson, Harry, Simpson, Liana, Simpson, Nathan Daniel, Simsek, Sinem, 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Bjarne, Stupak, John, Styles, Nicholas, Su, Dong, Su, Shixiang, Su, Wanyun, Su, Xiaowen, Sugizaki, Kaito, Sulin, Vladimir, Sullivan, Matthew James, Sultan, D.M.S., Sultanaliyeva, Laily, Sultanov, Salekh, Sumida, Toshi, Sun, Siyuan, Sun, Shaojun, Gudnadottir, Olga, Sur, Nairit, Sutton, Mark, Suzuki, Hisanori, Svatos, Michal, Swiatlowski, Maximilian J., Swirski, Thorben, Sykora, Ivan, Sykora, Martin, Sykora, Tomas, Ta, Duc Bao, Tackmann, Kerstin, Taffard, Anyes, Tafirout, Reda, Tafoya Vargas, Juan Salvador, Takeva, Emily Petrova, Takubo, Yosuke, Talby, Mossadek, Talyshev, Alexei, Tam, Kai Chung, Tamir, Nadav Michael, Tanaka, Aoto, Tanaka, Junichi, Tanaka, Rei, Tanasini, Martino, Tao, Zhengcheng, Tapia Araya, Sebastian, Tapprogge, Stefan, Tarek, Ahmed, Tarem, Shlomit, Tariq, Khuram, Tarna, Grigore, Tartarelli, Francesco, Tas, Petr, Tasevsky, Marek, Tassi, Enrico, Tate, Aric, Tateno, Gen, Tayalati, Yahya, Taylor, Geoffrey Norman, Taylor, Wendy Jane, Teagle, Hamish Edward, Tee, Amy, Teixeira De Lima, Rafael, Teixeira-Dias, Pedro, Teoh, Jia Jian, Terashi, Koji, Terron Cuadrado, Juan, Terzo, Stefano, Testa, Marianna, Teuscher, Richard, Thaler, Alexander, Theiner, Ondrej, Themistokleous, Neofytos, Theveneaux-Pelzer, Timothee, Thielmann, Oliver, Thomas, David William, Thomas, Juergen, Thompson, Emily Anne, Thompson, Paul, Thomson, Evelyn Jean, Tian, Yusong, Tikhomirov, Vladimir, Tikhonov, Iouri, Timoshenko, Sergei, Timoshyn, Denys, Ting, Edmund Xiang Lin, Tipton, Paul Louis, Tlou, Humphry, Tnourji, Abdellah, Todome, Kazuki, Todorova, Sarka, Todt, Stefanie, Togawa, Manabu, Tojo, Junji, Tokar, Stano, Tokushuku, Katsuo, Toldaiev, Alex, Tombs, Rupert, Tomoto, Makoto, Tompkins, Lauren Alexandra, Topolnicki, Kacper Wojciech, Torrence, Eric, Torres, Heberth, Torro Pastor, Emma, Toscani, Mariana, Tosciri, Cecilia, Tost, Marc, Tovey, Daniel, Traeet, Are Sivertsen, Trandafir, Iulia-Stefania, Trefzger, Thomas, Tricoli, Alessandro, Trigger, Isabel, Trincaz-Duvoid, Sophie, Trischuk, Dominique Anderson, Trocme, Benjamin, Troncon, Clara, Truong, Thi Ngoc Loan, Trzebinski, Maciej, Trzupek, Adam, Tsai, Fang-Ying, Tsai, Meng-Ju, Tsiamis, Angelos, Tsiareshka, Pavel, Tsigaridas, Stergios, Tsirigotis, Apostolos, Tsiskaridze, Vakhtang, Tskhadadze, Edisher, Tsopoulou, Maria-Evanthia, Tsujikawa, Yoshiaki, Tsukerman, Ilia, Tsulaia, Vakhtang, Tsuno, Soshi, Tsur, Omer, Tsuri, Kimu, Tsybyshev, Dmitry, Tu, Yanjun, Tudorache, Alexandra, Tudorache, Valentina, Tuna, Alexander Naip, Turchikhin, Semen, Turk Cakir, Ilkay, Turra, Ruggero, Turtuvshin, Tulgaa, Tuts, Mike, Tzamarias, Spyros, Tzanis, Polyneikis, Tzovara, Eftychia, Uchida, Kenta, Ukegawa, Fumihiko, Ulloa Poblete, Pablo Augusto, Umaka, Ejiro Naomi, Unal, Guillaume, Unal, Mesut, Undrus, Alexander, Unel, Gokhan, Urban, Josef, Urquijo, Phillip, Usai, Giulio, Ushioda, Risa, Usman, Muhammad, Uysal, Zekeriya, Vacavant, Laurent, Vacek, Vic, Vachon, Brigitte, Vadla, Knut Oddvar Hoie, Vafeiadis, Theodoros, Vaitkus, Andrius, 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Vgenopoulos, Andreas, Viaux Maira, Nicolas, Vickey, Trevor, Vickey Boeriu, Oana, Viehhauser, Georg, Vigani, Luigi, Villa, Mauro, Villaplana, Miguel, Villhauer, Elena Michelle, Vilucchi, Elisabetta, Vincter, Manuella, Virdee, Govindraj Singh, Vishwakarma, Akanksha, Visibile, Andrea, Vittori, Camilla, Vivarelli, Iacopo, Vladimirov, Vangelis, Voevodina, Elena, Vogel, Fabian, Vokac, Petr, Von Ahnen, Janik, Von Torne, Eckhard, Vormwald, Benedikt, Vorobel, Vit, Vorobev, Konstantin, Vos, Marcel, Voss, Katharina, Vossebeld, Joost, Vozak, Matous, Vozdecky, Lubos, Vranjes, Nenad, Vranjes Milosavljevic, Marija, Vreeswijk, Marcel, Vu, Ngoc Khanh, Vuillermet, Raphael, Vujinovic, Olivera, Vukotic, Ilija, Wada, Sayaka, Wagner, Cooper, Wagner, Johannes Michael, Wagner, Wolfgang, Wahdan, Shayma, Wahlberg, Hernan Pablo, Wakasa, Rena, Wakida, Moe, Walder, James William, Walker, Rodney, Walkowiak, Wolfgang, Wall, Andie, Wamorkar, Tanvi, Wang, Alex Zeng, Wang, Chen, Wang, Chenliang, Wang, Haichen, Wang, Jiawei, Wang, Renjie, Wang, Rongkun, Wang, Rui, Wang, Song-Ming, Wang, Shuanggeng, Wang, Tao, Wang, Weitao, Wang, Wei, Wang, Xin, Wang, Xiaoning, Wang, Xi, Wang, Yufeng, Wang, Yuhao, Wang, Zirui, Wang, Zhen, Wang, Zhichen, Warburton, Andreas, Ward, Robert James, Warrack, Neil, Watson, Alan, Watson, Harriet, Watson, Miriam, Watton, Elliot, Watts, Gordon, Waugh, Benedict Martin, Weber, Christian, Weber, Hannsjorg, Weber, Michele, Weber, Sebastian Mario, Wei, Chuanshun, Wei, Yingjie, Weidberg, Anthony, Weik, Edison James, Weingarten, Jens, Weirich, Marcel, Weiser, Christian, Wells, Craig John, Wenaus, Torre, Wendland, Bjoern, Wengler, Thorsten, Wenke, Nina Stephanie, Wermes, Norbert, Wessels, Martin, Whalen, Kate, Wharton, Andrew Mark, White, Aaron Stephen, White, Andrew, White, Martin John, Whiteson, Daniel, Wickremasinghe, Lakmin, Wiedenmann, Werner, Wiel, Christian, Wielers, Monika, Wiglesworth, Craig, Wilbern, Daniel John, Wilkens, Henric, Williams, Daniel, Williams, Hugh, Williams, Sarah Louise, Willocq, Stephane, Wilson, Benjamin James, Windischhofer, Philipp, Winkel, Federico, Winklmeier, Frank, Winter, Benedict Tobias, Winter, Joshua Krystian, Wittgen, Matthias, Wobisch, Markus, Wolffs, Zef, Woelker, Ricardo, Wollrath, Julian, Wolter, Marcin, Wolters, Helmut, Wongel, Alicia, Worm, Steven, Wosiek, Barbara Krystyna, Wozniak, Krzysztof Wieslaw, Wozniewski, Sebastian, Wraight, Kenneth Gibb, Wu, Chonghao, Wu, Jinfei, Wu, Minlin, Wu, Mengqing, Wu, Sau Lan, Wu, Xin, Wu, Yusheng, Wu, Zhibo, Wurzinger, Jonas, Wyatt, Terry, Wynne, Benjamin Michael, Xella, Stefania, Xia, Ligang, Xia, Mingming, Xiang, Jianhuan, Xiao, Xiong, Xie, Mingzhe, Xie, Xiangyu, Xin, Shuiting, Xiong, Junwen, Xu, Da, Xu, Hao, Xu, Lailin, Xu, Riley, Xu, Tairan, Xu, Yue, Xu, Zhongyukun, Xu, Zijun, Yabsley, Bruce Donald, Yacoob, Sahal, Yamaguchi, Naoki, Yamaguchi, Yohei, Yamashita, Erika, Yamauchi, Hiroki, Yamazaki, Tomohiro, Yamazaki, Yuji, Yan, Jun, Yan, Siyuan, Yan, Zhen, Yang, Haijun, Yang, Hongtao, Yang, Siqi, Yang, Tianyi, Yang, Xiao, Yang, Xuan, Yang, Yi-Lin, Yang, Yifan, Yang, Zhe, Yao, Wei-Ming, Yap, Yee Chinn, Ye, Hanfei, Ye, Hua, Ye, Jingbo, Ye, Shuwei, Ye, Xinmeng, Yeh, Yoran, Yeletskikh, Ivan, Yeo, Beom Ki, Yexley, Melissa, Yin, Pengqi, Yorita, Kohei, Younas, Sulman, Young, Christopher, Young, Charlie, Yu, Yi, Yuan, Man, Yuan, Rui, Yue, Luzhan, Zaazoua, Mohamed, Zabinski, Bartlomiej Henryk, Zaid, Estifa'A, Zakareishvili, Tamar, Zakharchuk, Nataliia, Zambito, Stefano, Zamora Saa, Jilberto Antonio, Zang, Jiaqi, Zanzi, Daniele, Zaplatilek, Ota, Zeitnitz, Christian, Zeng, Hao, Zeng, Jiancong, Zenger, Todd, Zenin, Oleg, Zenis, Tibor, Zenz, Seth, Zerradi, Soufiane, Zerwas, Dirk, Zhai, Mingjie, Zhang, Bowen, Zhang, Dengfeng, Zhang, Jie, Zhang, Jinlong, Zhang, Kaili, Zhang, Lei, Zhang, Peng, Zhang, Rui, Zhang, Shuzhou, Zhang, Tingyu, Zhang, Xiangke, Zhang, Xueyao, Zhang, Yulei, Zhang, Yuwen Ebony, Zhang, Zhicai, Zhang, Zhiqing Philippe, Zhao, Haoran, Zhao, Pingchuan, Zhao, Tongbin, Zhao, Yuzhan, Zhao, Zhengguo, Zhemchugov, Alexey, Zheng, Kai, Zheng, Xiangxuan, Zheng, Zhi, Zhong, Dewen, Zhou, Bing, Zhou, Hao, Zhou, Ning, Zhou, You, Zhu, Chengguang, Zhu, Junjie, Zhu, Yifan, Zhu, Yingchun, Zhuang, Xuai, Zhukov, Konstantin, Zhulanov, Vladimir, Zimine, Nikolai, Zinsser, Joachim, Ziolkowski, Michal, Zivkovic, Lidija, Zoccoli, Antonio, Zoch, Knut, Zorbas, Theodore, Zormpa, Olga, Zou, Wenkai, and Zwalinski, Lukasz

Subjects
High Energy Physics - Experiment (hep-ex), FOS: Physical sciences, Particle Physics - Experiment, High Energy Physics - Experiment
Abstract

A search for the single production of a vector-like top partner ($T$) decaying into a $Z$ boson and a top quark is presented, using the full Run 2 dataset corresponding to 139 $\mathrm{fb}^{-1}$ of $pp$ collisions at $\sqrt{s} = 13$ TeV, collected in 2015-2018 with the ATLAS detector at the Large Hadron Collider. The targeted final state is characterized by the presence of a pair of electrons or muons with opposite-sign charges which form a $Z$-boson candidate, as well as by the presence of $b$-tagged jets and forward jets. Events with exactly two or at least three leptons are categorized into two independently optimized analysis channels. No significant excess above the background expectation is observed and the results from the two channels are statistically combined to set exclusion limits at 95% confidence level on the masses and couplings of $T$ for different benchmark models and generalized branching ratio scenarios., 48 pages in total, author list starting page 31, 10 figures, 4 tables, submitted to Phys. Rev. D. All figures including auxiliary figures are available at http://atlas.web.cern.ch/Atlas/GROUPS/PHYSICS/PAPERS/EXOT-2020-01

Published
2023

49. Search for new phenomena in two-body invariant mass distributions using unsupervised machine learning for anomaly detection at $\sqrt{s} = 13$ TeV with the ATLAS detector

Author

Aad, Georges, Abbott, Braden Keim, Abeling, Kira, Abicht, Nils Julius, Abidi, Haider, Aboulhorma, Asmaa, Abramowicz, Halina, Abreu, Henso, Abulaiti, Yiming, Abusleme, Angel, Acharya, Bobby Samir, Adam Bourdarios, Claire, Adamczyk, Leszek, Adamek, Lukas, Addepalli, Sagar, Addison, Matt, Adelman, Jahred, Adiguzel, Aytul, Adye, Tim, Affolder, Tony, Afik, Yoav, Agaras, Merve Nazlim, Agarwala, Jinky, Aggarwal, Anamika, Agheorghiesei, Catalin, Ahmad, Ammara, Ahmadov, Faig, Ahmed, Waleed Syed, Ahuja, Sudha, Ai, Xiaocong, Aielli, Giulio, Aikot, Arya, Ait Tamlihat, Malak, Aitbenchikh, Brahim, Aizenberg, Iakov, Akbiyik, Melike, Akesson, Torsten, Akimov, Andrei, Akiyama, Daiya, Akolkar, Nilima Nilesh, Al Khoury, Konie, Alberghi, Gian Luigi, Albert, Justin, Albicocco, Pietro, Albouy, Guillaume Lucas, Alderweireldt, Sara, Aleksa, Martin, Alexandrov, Igor, Alexa, Calin, Alexopoulos, Theodoros, Alfonsi, Fabrizio, Algren, Malte, Alhroob, Muhammad, Ali, Babar, Ali, Hanadi, Ali, Shahzad, Alibocus, Samuel William, Aliev, Malik, Alimonti, Gianluca, Alkakhi, Wael, Allaire, Corentin, Allbrooke, Benedict, Allen, Julia Frances, Allendes Flores, Cristian Andres, Allport, Philip Patrick, Aloisio, Alberto, Alonso, Francisco, Alpigiani, Cristiano, Alvarez Estevez, Manuel, Alvarez Fernandez, Adrian, Alves Cardoso, Mario, Alviggi, Mariagrazia, Aly, Mohamed, Do Amaral Coutinho, Yara, Ambler, Alessandro, Amelung, Christoph, Amerl, Maximilian, Ames, Christoph, Amidei, Dante, Amor Dos Santos, Susana Patricia, Amos, Kieran Robert, Ananiev, Viktor, Anastopoulos, Christos, Andeen, Timothy Robert, Anders, John Kenneth, Andrean, Stefio Yosse, Andreazza, Attilio, Angelidakis, Stylianos, Angerami, Aaron, Anisenkov, Alexey, Annovi, Alberto, Antel, Claire, Anthony, Matthew Thomas, Antipov, Egor, Antonelli, Mario, Anulli, Fabio, Aoki, Masato, Aoki, Takumi, Aparisi Pozo, Javier Alberto, Aparo, Marco, Aperio Bella, Ludovica, Appelt, Christian, Apyan, Aram, Aranzabal Barrio, Nordin, Arcangeletti, Chiara, Arce, Ayana Tamu, Arena, Eloisa, Arguin, Jean-Francois, Argyropoulos, Spyros, Arling, Jan-Hendrik, Arnaez, Olivier, Arnold, Hannah, Artoni, Giacomo, Asada, Haruka, Asai, Kanae, Asai, Shoji, Asbah, Nedaa Alexandra, Assahsah, Jihad, Assamagan, Ketevi Adikle, Astalos, Robert, Atashi, Rose, Atkin, Ryan Justin, Atkinson, Markus Julian, Atmani, Hicham, Atmasiddha, Prachi, Augsten, Kamil, Auricchio, Silvia, Auriol, Adrien, Austrup, Volker Andreas, Avolio, Giuseppe, Axiotis, Konstantinos, Azuelos, Georges, Babal, Dominik, Bachacou, Henri, Bachas, Konstantinos, Bachiu, Alexander, Backman, Karl Filip, Badea, Anthony, Bagnaia, Paolo, Bahmani, Marzieh, Bailey, Adam, Bailey, Virginia, Baines, John, Baines, Luke, Bakalis, Christos, Baker, Keith, Bakos, Evelin, Bakshi Gupta, Debottam, Balakrishnan, Veena, Balasubramanian, Rahul, Baldin, Evgenii, Balek, Petr, Ballabene, Eric, Balli, Fabrice, Baltes, Lisa Marie, Balunas, William Keaton, Balz, Johannes, Banas, Elzbieta, Bandieramonte, Marilena, Bandyopadhyay, Anjishnu, Bansal, Shubham, Barak, Liron, Barakat, Marawan, Barberio, Elisabetta, Barberis, Dario, Barbero, Marlon Benoit, Barends, Kevin Nicholas, Barillari, Teresa, Barisits, Martin, Barklow, Tim, Baron, Petr, Baron, Diego, Baroncelli, Toni, Barone, Gaetano, Barr, Alan, Barr, Jackson, Barranco Navarro, Laura, Barreiro Alonso, Fernando, Barreiro Guimaraes Da Costa, Joao, Barron, Uriel, Barros, Maura, Barsov, Sergey, Bartels, Falk, Bartoldus, Rainer, Barton, Adam Edward, Bartos, Pavol, Basan, Alexander, Baselga Bacardit, Marta, Bassalat, Ahmed, Basso, Matthew Joseph, Basson, Candice Ruth, Bates, Richard, Batlamous, Souad, Batley, Richard, Batool, Binish, Battaglia, Marco, Battulga, Daariimaa, Bauce, Matteo, Bauer, Michael, Bauer, Patrick, Bazzano, Tomas, Beacham, James, Beau, Tristan, Beauchemin, Pierre-Hugues, Becherer, Fabian, Bechtle, Philip, Beck, Hans Peter, Becker, Kathrin, Beddall, Andrew, Bednyakov, Vadim, Bee, Chris, Beemster, Lars, Beermann, Thomas, Begalli, Marcia, Begel, Michael, Behera, Arabinda, Behr, Janna Katharina, Beirer, Joshua Falco, Beisiegel, Florian, Belfkir, Mohamed, Bella, Gideon, Bellagamba, Lorenzo, Bellerive, Alain, Bellos, Panagiotis, Beloborodov, Konstantin, Belyaev, Nikita, Benchekroun, Driss, Bendebba, Fatima, Benhammou, Yan, Benoit, Mathieu, Bensinger, Jim, Bentvelsen, Stan, Beresford, Lydia Audrey, Beretta, Matteo Mario, Bergeaas Kuutmann, Elin, Berger, Nicolas, Bergmann, Benedikt Ludwig, Beringer, Juerg, Bernardi, Gregorio, Bernius, Catrin, Bernlochner, Florian Urs, Bernon, Florent, Berry, Tracey, Berta, Peter, Berthold, Anne-Sophie, Bertram, Iain, Bethke, Siegfried, Betti, Alessandra, Bevan, Adrian, Bhamjee, Muaaz, Bhatta, Somadutta, Bhattacharya, Deb Sankar, Bhattarai, Prajita, Bhopatkar, Vallary Shashikant, Bi, Ran, Bianchi, Riccardo Maria, Bianco, Gianluca, Biebel, Otmar, Bielski, Rafal, Biglietti, Michela, Billoud, Thomas, Bindi, Marcello, Bingul, Ahmet, Bini, Cesare, Biondini, Alessandro, Birch-Sykes, Callum Jacob, Bird, Gareth Adam, Birman, Mattias, Biros, Marek, Biryukov, Stanislav, Bisanz, Tobias, Bisceglie, Emanuele, Biswal, Jyoti Prakash, Biswas, Diptaparna, Bitadze, Alexander, Bjoerke, Kristian, Bloch, Ingo, Blocker, Craig, Blue, Andrew James, Blumenschein, Ulla, Blumenthal, Julian, Bobbink, Gerjan, Bobrovnikov, Viktor, Boehler, Michael, Bohm, Burkhard, Bogavac, Danijela, Bogdanchikov, Alexander, Bohm, Christian, Boisvert, Veronique, Bokan, Petar, Bold, Tomasz, Bomben, Marco, Bona, Marcella, Boonekamp, Maarten, Booth, Callum Dale, Borbely, Albert Gyorgy, Bordulev, Iurii, Borecka-Bielska, Hanna Maria, Borgna, Lucas Santiago, Borissov, Guennadi, Bortoletto, Daniela, Boscherini, Davide, Fernandez-Bosman, Martine, Bossio, Jonathan, Bouaouda, Khalil, Bouchhar, Naseem, Boudreau, Joseph, Bouhova-Thacker, Eva, Boumediene, Djamel Eddine, Bouquet, Romain, Boveia, Antonio, Boyd, Jamie, Boye, Diallo, Boyko, Igor, Bracinik, Juraj, Brahimi, Nihal, Brandt, Gerhard Immanuel, Brandt, Oleg, Braren, 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Khandoga, Mykola, Khanov, Alexander, Kharlamov, Alexey, Kharlamova, Tatyana, Khoda, Elham E., Khoo, Teng Jian, Khoriauli, Gia, Khubua, Djemal, Khwaira, Yahya A.R., Kilgallon, Aaron Joseph, Kim, Dongwon, Kim, Young-Kee, Kimura, Naoki, Kingston, Matthew Kevin, Kirchhoff, Andreas, Kirfel, Christian, Kirfel, Florian, Kirk, Julie, Kiryunin, Andrei, Kitsaki, Chara, Kivernyk, Oleh, Klassen, Martin, Klein, Christoph Thomas, Klein, Lucas, Klein, Matthew Henry, Klein, Max, Klein, Samuel Byrne, Klein, Uta, Klimek, Pawel Jan, Klimentov, Alexei, Klioutchnikova, Tatiana, Kluit, Peter, Kluth, Stefan, Kneringer, Emmerich, Knight, Timothy Michael, Knue, Andrea Helen, Kobayashi, Ren, Kobylianskii, Dmitrii, Koch, Simon Florian, Kocian, Martin, Kodys, Peter, Kock, Daniela, Konig, Philipp, Koffas, Thomas, Kolb, Mathis, Koletsou, Iro, Komarek, Tomas, Koeneke, Karsten, Kong, Albert, Kono, Takanori, Konstantinidis, Nikolaos, Konya, Balazs, Kopeliansky, Revital, Koperny, Stefan Zenon, Korcyl, Krzysztof Marian, 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Lundberg, Olof, Lund-Jensen, Bengt, Luongo, Nicholas, Lutz, Margaret Susan, Lynn, David, Lyons, Harry John, Lysak, Roman, Lytken, Else, Lyubushkin, Vladimir, Lyubushkina, Tatiana, Lyukova, Mars, Ma, Hong, Ma, Kuo, Ma, Lianliang, Ma, Yanhui, Macdonell, Danika Marina, Maccarrone, Giovanni, Macdonald, Jack, Machado De Abreu Farias, Paulo Cesar, Madar, Romain, Mader, Wolfgang, Madula, Thandikire, Maeda, Junpei, Maeno, Tadashi, Maerker, Max, Maguire, Helen Ruth, Maiboroda, Vera, Maio, Amelia, Maj, Klaudia, Majersky, Oliver, Majewski, Stephanie, Makovec, Nikola, Maksimovic, Veljko, Malaescu, Bogdan, Malecki, Pawel, Maleev, Victor, Malek, Fairouz, Mali, Miha, Malito, Davide, Mallik, Usha, Maltezos, Stavros, Malyukov, Sergey, Mamuzic, Judita, Mancini, Giada, Manco, Giulia, Mandalia, Jesal, Mandic, Igor, Manhaes De Andrade Filho, Luciano, Maniatis, Ioannis Michail, Manjarres, Joany, Mankad, Dvij, Mann, Alexander, Mansoulie, Bruno, Manzoni, Stefano, Marantis, Alexandros, Marchiori, Giovanni, 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Perez, David, Munoz Sanchez, Francisca, Murin, Martin, Murray, Bill, Murrone, Alessia, Muse, Joseph M., Muskinja, Miha, Mwewa, Chilufya, Myagkov, Alexei, Myers, Andrew Joel, Myers, Ava Anne, Myers, Greg, Myska, Miroslav, Nachman, Ben, Nackenhorst, Olaf, Nag, Abhishek, Nagai, Koichi, Nagano, Kunihiro, Nagle, James Lawrence, Nagy, Elemer, Nairz, Armin, Nakahama Higuchi, Yu, Nakamura, Koji, Nakkalil, Keerthi, Nanjo, Hajime, Narayan, Rohin Thampilali, Narayanan, Easwar Anand, Naryshkin, Iurii, Naseri, Mohsen, Nasri, Salah, Nass, Christian, Navarro, Gabriela Alejandra, Navarro Gonzalez, Josep, Nayak, Ranjit, Nayaz, Ab, Nechaeva, Polina, Nechansky, Filip, Nedic, Luka, Neep, Tom, Negri, Andrea, Negrini, Matteo, Nellist, Clara, Nelson, Christina, Nelson, Kevin Michael, Nemecek, Stanislav, Nessi, Marzio, Neubauer, Mark, Neuhaus, Friedemann, Neundorf, Jonas, Newhouse, Robin, Newman, Paul Richard, Ng, Chi Wing, Ng, Ying Wun Yvonne, Ngair, Badr-Eddine, Nguyen, Hoang Dai Nghia, Nickerson, Richard, 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Daniel, Simsek, Sinem, Sindhu, Sreelakshmi, Sinervo, Pekka, Singh, Sahibjeet, Sinha, Supriya, Sinha, Sukanya, Sioli, Maximiliano, Siral, Ismet, Sitnikova, Elizaveta, Sivoklokov, Serguei, Sjoelin, Joergen, Skaf, Ali, Skorda, Eleni, Skubic, Patrick, Slawinska, Magdalena, Smakhtin, Vladimir, Smart, Ben Harry, Smiesko, Juraj, Smirnov, Serge, Smirnov, Yury, Smirnova, Lidia, Smirnova, Oxana, Smith, Andrew Caldon, Smith, Emily Ann, Smith, Hayden Alexander, Smith, James, Smith, Rachel Emma Clarke, Smizanska, Maria, Smolek, Karel, Snesarev, Andrei, Snider, Sean Robert, Snoek, Hella, Snyder, Scott, Sobie, Randy, Soffer, Abi, Solans Sanchez, Carlos, Soldatov, Evgeny, Soldevila Serrano, Urmila, Solodkov, Sanya, Solomon, Shalu, Soloshenko, Aleksey, Solovieva, Ksenia, Solovyanov, Oleg, Solovyev, Victor, Sommer, Philip, Sonay, Anil, Song, Wen Yi, Sonneveld, Jory, Sopczak, Andre, Sopio, Alex, Sopkova, Filomena, Sothilingam, Varsiha, Sottocornola, Simone, Soualah, Rachik, Soumaimi, Zainab, South, 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Andrius, Valderanis, Chrysostomos, Valdes Santurio, Eduardo, Valente, Marco, Valentinetti, Sara, Valero Biot, Alberto, Valiente Moreno, Enrique, Vallier, Alexis, Valls Ferrer, Juan, Van Arneman, Dylan Remberto, Van Daalen, Tal Roelof, Van Der Graaf, Aaron, Van Gemmeren, Peter, Van Rijnbach, Milou, Van Stroud, Samuel, Van Vulpen, Ivo, Vanadia, Marco, Vandelli, Wainer, Vandenbroucke, Maxence, Van De Wall, Evan Richard, Vannicola, Damiano, Vannoli, Leonardo, Vari, Riccardo, Varnes, Erich Ward, Varni, Carlo, Mete, Tulin, Varouchas, Dimitris, Varriale, Lorenzo, Varvell, Kevin, Vasile, Matei, Vaslin, Louis, Vasquez, Gerardo, Vasyukov, Artem, Vazeille, Francois, Vazquez Schroeder, Tamara, Veatch, Jason Robert, Vecchio, Valentina, Veen, Michiel Jan, Veliscek, Iza, Veloce, Laurelle Maria, Veloso, Filipe, Veneziano, Stefano, Ventura, Andrea, Ventura Gonzalez, Salvador, Verbytskyi, Andrii, Verducci, Monica, Vergis, Christos, Verissimo De Araujo, Micael, Verkerke, Wouter, Vermeulen, Jos, Vernieri, 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Zeng, Wang, Chen, Wang, Chenliang, Wang, Haichen, Wang, Jiawei, Wang, Renjie, Wang, Rongkun, Wang, Rui, Wang, Song-Ming, Wang, Shuanggeng, Wang, Tao, Wang, Weitao, Wang, Wei, Wang, Xin, Wang, Xiaoning, Wang, Xi, Wang, Yufeng, Wang, Yuhao, Wang, Zirui, Wang, Zhen, Wang, Zhichen, Warburton, Andreas, Ward, Robert James, Warrack, Neil, Watson, Alan, Watson, Harriet, Watson, Miriam, Watton, Elliot, Watts, Gordon, Waugh, Benedict Martin, Weber, Christian, Weber, Hannsjorg, Weber, Michele, Weber, Sebastian Mario, Wei, Chuanshun, Wei, Yingjie, Weidberg, Anthony, Weik, Edison James, Weingarten, Jens, Weirich, Marcel, Weiser, Christian, Wells, Craig John, Wenaus, Torre, Wendland, Bjoern, Wengler, Thorsten, Wenke, Nina Stephanie, Wermes, Norbert, Wessels, Martin, Wharton, Andrew Mark, White, Aaron Stephen, White, Andrew, White, Martin John, Whiteson, Daniel, Wickremasinghe, Lakmin, Wiedenmann, Werner, Wiel, Christian, Wielers, Monika, Wiglesworth, Craig, Wilbern, Daniel John, Wilkens, Henric, Williams, Daniel, Williams, Hugh, Williams, Sarah Louise, Willocq, Stephane, Wilson, Benjamin James, Windischhofer, Philipp, Winkel, Federico, Winklmeier, Frank, Winter, Benedict Tobias, Winter, Joshua Krystian, Wittgen, Matthias, Wobisch, Markus, Wolffs, Zef, Wollrath, Julian, Wolter, Marcin, Wolters, Helmut, Wongel, Alicia, Worm, Steven, Wosiek, Barbara Krystyna, Wozniak, Krzysztof Wieslaw, Wozniewski, Sebastian, Wraight, Kenneth Gibb, Wu, Chonghao, Wu, Jinfei, Wu, Minlin, Wu, Mengqing, Wu, Sau Lan, Wu, Xin, Wu, Yusheng, Wu, Zhibo, Wurzinger, Jonas, Wyatt, Terry, Wynne, Benjamin Michael, Xella, Stefania, Xia, Ligang, Xia, Mingming, Xiang, Jianhuan, Xie, Mingzhe, Xie, Xiangyu, Xin, Shuiting, Xiong, Junwen, Xu, Da, Xu, Hao, Xu, Lailin, Xu, Riley, Xu, Tairan, Xu, Yue, Xu, Zhongyukun, Xu, Zijun, Yabsley, Bruce Donald, Yacoob, Sahal, Yamaguchi, Yohei, Yamashita, Erika, Yamauchi, Hiroki, Yamazaki, Tomohiro, Yamazaki, Yuji, Yan, Jun, Yan, Siyuan, Yan, Zhen, Yang, Haijun, Yang, Hongtao, Yang, Siqi, Yang, Tianyi, Yang, Xiao, Yang, Xuan, Yang, Yi-Lin, Yang, Yifan, Yang, Zhe, Yao, Wei-Ming, Yap, Yee Chinn, Ye, Hanfei, Ye, Hua, Ye, Jingbo, Ye, Shuwei, Ye, Xinmeng, Yeh, Yoran, Yeletskikh, Ivan, Yeo, Beom Ki, Yexley, Melissa, Yin, Pengqi, Yorita, Kohei, Younas, Sulman, Young, Christopher, Young, Charlie, Yu, Yi, Yuan, Man, Yuan, Rui, Yue, Luzhan, Zaazoua, Mohamed, Zabinski, Bartlomiej Henryk, Zaid, Estifa'A, Zakareishvili, Tamar, Zakharchuk, Nataliia, Zambito, Stefano, Zamora Saa, Jilberto Antonio, Zang, Jiaqi, Zanzi, Daniele, Zaplatilek, Ota, Zeitnitz, Christian, Zeng, Hao, Zeng, Jiancong, Zenger, Todd, Zenin, Oleg, Zenis, Tibor, Zenz, Seth, Zerradi, Soufiane, Zerwas, Dirk, Zhai, Mingjie, Zhang, Bowen, Zhang, Dengfeng, Zhang, Jie, Zhang, Jinlong, Zhang, Kaili, Zhang, Lei, Zhang, Peng, Zhang, Rui, Zhang, Shuzhou, Zhang, Tingyu, Zhang, Xiangke, Zhang, Xueyao, Zhang, Yulei, Zhang, Yuwen Ebony, Zhang, Zhicai, Zhang, Zhiqing Philippe, Zhao, Haoran, Zhao, Pingchuan, Zhao, Tongbin, Zhao, Yuzhan, Zhao, Zhengguo, Zhemchugov, Alexey, Zheng, Jinchao, Zheng, Kai, Zheng, Xiangxuan, Zheng, Zhi, Zhong, Dewen, Zhou, Bing, Zhou, Hao, Zhou, Ning, Zhou, You, Zhu, Chengguang, Zhu, Junjie, Zhu, Yifan, Zhu, Yingchun, Zhuang, Xuai, Zhukov, Konstantin, Zhulanov, Vladimir, Zimine, Nikolai, Zinsser, Joachim, Ziolkowski, Michal, Zivkovic, Lidija, Zoccoli, Antonio, Zoch, Knut, Zorbas, Theodore, Zormpa, Olga, Zou, Wenkai, Zwalinski, Lukasz, Centre de Physique des Particules de Marseille (CPPM), Aix Marseille Université (AMU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'Annecy de Physique des Particules (LAPP), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique Subatomique et de Cosmologie (LPSC), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ), Université Grenoble Alpes (UGA), Laboratoire de Physique des 2 Infinis Irène Joliot-Curie (IJCLab), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE (UMR_7585)), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Laboratoire de Physique de Clermont (LPC), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université Clermont Auvergne (UCA), Laboratoire des deux Infinis de Toulouse (L2IT), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), and ATLAS

Subjects
electron, lepton, background, p p, scattering, photon, FOS: Physical sciences, anomaly, ATLAS, High Energy Physics - Experiment, mass spectrum, High Energy Physics - Experiment (hep-ex), machine learning, CERN LHC Coll, muon, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], TeV, Particle Physics - Experiment
Abstract

Searches for new resonances are performed using an unsupervised anomaly-detection technique. Events with at least one electron or muon are selected from 140 fb$^{-1}$ of $pp$ collisions at $\sqrt{s} = 13$ TeV recorded by ATLAS at the Large Hadron Collider. The approach involves training an autoencoder on data, and subsequently defining anomalous regions based on the reconstruction loss of the decoder. Studies focus on nine invariant mass spectra that contain pairs of objects consisting of one light jet or $b$-jet and either one lepton ($e$, $\mu$), photon, or second light jet or $b$-jet in the anomalous regions. No significant deviations from the background hypotheses are observed., Comment: 32 pages in total, author list starting page 15, 4 figures, submitted to Phys. Rev. Lett. All figures including auxiliary figures are available at: http://atlas.web.cern.ch/Atlas/GROUPS/PHYSICS/PAPERS/EXOT-2022-07

Published
2023

50. Measurement of the $H \to \gamma \gamma$ and $H \to ZZ^* \to 4 \ell$ cross-sections in $pp$ collisions at $\sqrt{s}=13.6$ TeV with the ATLAS detector

Author

Aad, Georges, Abbott, Braden Keim, Abeling, Kira, Abicht, Nils Julius, Abidi, Haider, Aboulhorma, Asmaa, Abramowicz, Halina, Abreu, Henso, Abulaiti, Yiming, Acharya, Bobby Samir, Adam Bourdarios, Claire, Adamczyk, Leszek, Adamek, Lukas, Addepalli, Sagar, Addison, Matt, Adelman, Jahred, Adiguzel, Aytul, Adye, Tim, Affolder, Tony, Afik, Yoav, Agaras, Merve Nazlim, Agarwala, Jinky, Aggarwal, Anamika, Agheorghiesei, Catalin, Ahmad, Ammara, Ahmadov, Faig, Ahmed, Waleed Syed, Ahuja, Sudha, Ai, Xiaocong, Aielli, Giulio, Aikot, Arya, Ait Tamlihat, Malak, Aitbenchikh, Brahim, Aizenberg, Iakov, Akbiyik, Melike, Akesson, Torsten, Akimov, Andrei, Akiyama, Daiya, Akolkar, Nilima Nilesh, Al Khoury, Konie, Alberghi, Gian Luigi, Albert, Justin, Albicocco, Pietro, Albouy, Guillaume Lucas, Alderweireldt, Sara, Aleksa, Martin, Alexandrov, Igor, Alexa, Calin, Alexopoulos, Theodoros, Alfonsi, Fabrizio, Algren, Malte, Alhroob, Muhammad, Ali, Babar, Ali, Hanadi, Ali, Shahzad, Alibocus, Samuel William, Aliev, Malik, Alimonti, Gianluca, Alkakhi, Wael, Allaire, Corentin, Allbrooke, Benedict, Allen, Julia Frances, Allendes Flores, Cristian Andres, Allport, Philip Patrick, Aloisio, Alberto, Alonso, Francisco, Alpigiani, Cristiano, Alvarez Estevez, Manuel, Alvarez Fernandez, Adrian, Alves Cardoso, Mario, Alviggi, Mariagrazia, Aly, Mohamed, Do Amaral Coutinho, Yara, Ambler, Alessandro, Amelung, Christoph, Amerl, Maximilian, Ames, Christoph, Amidei, Dante, Amor dos Santos, Susana Patricia, Amos, Kieran Robert, Ananiev, Viktor, Anastopoulos, Christos, Andeen, Timothy Robert, Anders, John Kenneth, Andrean, Stefio Yosse, Andreazza, Attilio, Angelidakis, Stylianos, Angerami, Aaron, Anisenkov, Alexey, Annovi, Alberto, Antel, Claire, Anthony, Matthew Thomas, Antipov, Egor, Antonelli, Mario, Anulli, Fabio, Aoki, Masato, Aoki, Takumi, Aparisi Pozo, Javier Alberto, Aparo, Marco, Aperio Bella, Ludovica, Appelt, Christian, Apyan, Aram, Aranzabal Barrio, Nordin, Arcangeletti, Chiara, Arce, Ayana Tamu, Arena, Eloisa, Arguin, Jean-Francois, Argyropoulos, Spyros, Arling, Jan-Hendrik, Arnaez, Olivier, Arnold, Hannah, Artoni, Giacomo, Asada, Haruka, Asai, Kanae, Asai, Shoji, Asbah, Nedaa Alexandra, Assahsah, Jihad, Assamagan, Ketevi Adikle, Astalos, Robert, Atashi, Rose, Atkin, Ryan Justin, Atkinson, Markus Julian, Atmani, Hicham, Atmasiddha, Prachi, Augsten, Kamil, Auricchio, Silvia, Auriol, Adrien, Austrup, Volker Andreas, Avolio, Giuseppe, Axiotis, Konstantinos, Azuelos, Georges, Babal, Dominik, Bachacou, Henri, Bachas, Konstantinos, Bachiu, Alexander, Backman, Karl Filip, Badea, Anthony, Bagnaia, Paolo, Bahmani, Marzieh, Bailey, Adam, Bailey, Virginia, Baines, John, Baines, Luke, Bakalis, Christos, Baker, Keith, Bakos, Evelin, Bakshi Gupta, Debottam, Balakrishnan, Veena, Balasubramanian, Rahul, Baldin, Evgenii, Balek, Petr, Ballabene, Eric, Balli, Fabrice, Baltes, Lisa Marie, Balunas, William Keaton, Balz, Johannes, Banas, Elzbieta, Bandieramonte, Marilena, Bandyopadhyay, Anjishnu, Bansal, Shubham, Barak, Liron, Barakat, Marawan, Barberio, Elisabetta, Barberis, Dario, Barbero, Marlon Benoit, Barel, Marten Zefanja, Barends, Kevin Nicholas, Barillari, Teresa, Barisits, Martin, Barklow, Tim, Baron, Petr, Baron, Diego, Baroncelli, Toni, Barone, Gaetano, Barr, Alan, Barr, Jackson, Barranco Navarro, Laura, Barreiro Alonso, Fernando, Barreiro Guimaraes da Costa, Joao, Barron, Uriel, Barros, Maura, Barsov, Sergey, Bartels, Falk, Bartoldus, Rainer, Barton, Adam Edward, Bartos, Pavol, Basan, Alexander, Baselga Bacardit, Marta, Bassalat, Ahmed, Basso, Matthew Joseph, Basson, Candice Ruth, Bates, Richard, Batlamous, Souad, Batley, Richard, Batool, Binish, Battaglia, Marco, Battulga, Daariimaa, Bauce, Matteo, Bauer, Michael, Bauer, Patrick, Bazzano, Tomas, Beacham, James, Beau, Tristan, Beauchemin, Pierre-Hugues, Becherer, Fabian, Bechtle, Philip, Beck, Hans Peter, Becker, Kathrin, Beddall, Andrew, Bednyakov, Vadim, Bee, Chris, Beemster, Lars, Beermann, Thomas, Begalli, Marcia, Begel, Michael, Behera, Arabinda, Behr, Janna Katharina, Beirer, Joshua Falco, Beisiegel, Florian, Belfkir, Mohamed, Bella, Gideon, Bellagamba, Lorenzo, Bellerive, Alain, Bellos, Panagiotis, Beloborodov, Konstantin, Benchekroun, Driss, Bendebba, Fatima, Benhammou, Yan, Benoit, Mathieu, Bensinger, Jim, Bentvelsen, Stan, Beresford, Lydia Audrey, Beretta, Matteo Mario, Bergeaas Kuutmann, Elin, Berger, Nicolas, Bergmann, Benedikt Ludwig, Beringer, Juerg, Bernardi, Gregorio, Bernius, Catrin, Bernlochner, Florian Urs, Bernon, Florent, Berry, Tracey, Berta, Peter, Berthold, Anne-Sophie, Bertram, Iain, Bethke, Siegfried, Betti, Alessandra, Bevan, Adrian, Bhalla, Naman Kumar, Bhamjee, Muaaz, Bhatta, Somadutta, Bhattacharya, Deb Sankar, Bhattarai, Prajita, Bhopatkar, Vallary Shashikant, Bi, Ran, Bianchi, Riccardo Maria, Bianco, Gianluca, Biebel, Otmar, Bielski, Rafal, Biglietti, Michela, Bindi, Marcello, Bingul, Ahmet, Bini, Cesare, Biondini, Alessandro, Birch-Sykes, Callum Jacob, Bird, Gareth Adam, Birman, Mattias, Biros, Marek, Biryukov, Stanislav, Bisanz, Tobias, Bisceglie, Emanuele, Biswal, Jyoti Prakash, Biswas, Diptaparna, Bitadze, Alexander, Bjoerke, Kristian, Bloch, Ingo, Blocker, Craig, Blue, Andrew James, Blumenschein, Ulla, Blumenthal, Julian, Bobbink, Gerjan, Bobrovnikov, Viktor, Boehler, Michael, Bohm, Burkhard, Bogavac, Danijela, Bogdanchikov, Alexander, Bohm, Christian, Boisvert, Veronique, Bokan, Petar, Bold, Tomasz, Bomben, Marco, Bona, Marcella, Boonekamp, Maarten, Booth, Callum Dale, Borbely, Albert Gyorgy, Bordulev, Iurii, Borecka-Bielska, Hanna Maria, Borissov, Guennadi, Bortoletto, Daniela, Boscherini, Davide, Fernandez-Bosman, Martine, Bossio, Jonathan, Bouaouda, Khalil, Bouchhar, Naseem, Boudreau, Joseph, Bouhova-Thacker, Eva, Boumediene, Djamel Eddine, Bouquet, Romain, Boveia, Antonio, Boyd, Jamie, Boye, Diallo, Boyko, Igor, Bracinik, Juraj, Brahimi, Nihal, Brandt, Gerhard Immanuel, Brandt, Oleg, Braren, Frued Erik, Brau, Benjamin Paul, Brau, Jim, Schimmel Brener, Roy, Brenner, Lydia, Brenner, Richard, Bressler, Shikma, Britton, David, Britzger, Daniel Andreas, Brock, Ian, Brooijmans, Gustaaf, Brooks, William King, Brost, Elizabeth, Brown, Leesa Marea, Bruce, Laura Elaine, Bruckler, Tim Lukas, Bruckman de Renstrom, Pawel, Bruers, Ben, Bruni, Alessia, Bruni, Graziano, Bruschi, Marco, Bruscino, Nello, Buanes, Trygve, Buat, Quentin, Buchin, Daniel, Buckley, Andy, Bulekov, Oleg, Bullard, Brendon, Burdin, Sergey, Burgard, Carsten, Burger, Angela Maria, Burghgrave, Blake Oliver, Burlayenko, Oleksandr, Burr, Jon, Burton, Charles, Burzynski, Jackson Carl, Busch, Elena Laura, Buescher, Volker, Bussey, Peter John, Butler, John Mark, Buttar, Craig Macleod, Butterworth, Jonathan, Buttinger, Will, Buxo Vazquez, Carlos Josue, Buzykaev, Alexey, Cabrera Urban, Susana, Cadamuro, Luca, Caforio, Davide, Cai, Huacheng, Cai, Yuchen, Cairo, Valentina, Cakir, Orhan, Calace, Noemi, Calafiura, Paolo, Calderini, Giovanni, Calfayan, Philippe, Callea, Giuseppe, Caloba, Luiz, Calvet, David, Calvet, Samuel, Calvet, Thomas Philippe, Calvetti, Milene, Camacho Toro, Reina Coromoto, Camarda, Stefano, Camarero Munoz, Daniel, Camarri, Paolo, Camerlingo, Maria Teresa, Cameron, David, Camincher, Clement, Campanelli, Mario, Camplani, Alessandra, Canale, Vincenzo, Canesse, Auriane, Cantero Garcia, Josu, Cao, Yumeng, Capocasa, Francesca, Capua, Marcella, Carbone, Antonio, Cardarelli, Roberto, Cardenas, Juan Carlos, Cardillo, Fabio, Carli, Tancredi, Carlino, Giampaolo, Carlotto, Juan Ignacio, Carlson, Ben, Carlson, Evan Michael, Carminati, Leonardo, Carnelli, Alberto, Carnesale, Maria, Caron, Sascha, Carquin Lopez, Edson, Carra, Sonia, Carratta, Giuseppe, Carrio Argos, Fernando, Carter, Joseph, Carter, Thomas Michael, Casado Lechuga, Pilar, Caspar, Maximilian, Castiglia, Emma Grace, Castillo, Florencia Luciana, Castillo Garcia, Lucia, Castillo Gimenez, Victoria, Castro, Nuno, Catinaccio, Andrea, Catmore, James, Cavaliere, Viviana, Cavalli, Noemi, 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Giannetti, Paola, Giannini, Antonio, Gibson, Stephen, Gignac, Matthew, Gil, Damian Tomasz, Gilbert, Alexander Kevin, Gilbert, Benjamin Jacob, Gillberg, Dag, Gilles, Geoffrey, Gillwald, Nils, Ginabat, Louis, Gingrich, Doug, Giordani, Mapo, Giraud, Pierre-Francois, Giugliarelli, Gilberto, Giugni, Danilo, Giuli, Francesco, Gkialas, Ioannis, Gladilin, Leonid, Glasman, Claudia, Gledhill, Galen Rhodes, Glemza, Gediminas, Glisic, Marija, Gnesi, Ivan, Go, Yeonju, Goblirsch-Kolb, Maximilian Emanuel, Gocke, Benedikt, Godin, Dominique, Gokturk, Berare, Goldfarb, Steven, Golling, Tobias, Gololo, Mpho Gift Doctor, Golubkov, Dmitry, Gombas, Jason Peter, da Silva Gomes, Agostinho, Gomes, Gabriel, Gomez Delegido, Antonio Jesus, Morais Silva Goncalo, Ricardo Jose, Gonella, Giulia, Gonella, Laura, Gongadze, Alexi, Gonnella, Francesco, Gonski, Julia Lynne, Gonzalez, Richards, Gonzalez de la Hoz, Santiago, Gonzalez Fernandez, Sergio, Gonzalez Lopez, Ricardo, Gonzalez Renteria, Cesar, Gonzalez Rodrigues, 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Yun-Ju, Lubatti, Henry, Luci, Claudio, Lucio Alves, Fabio Lucio, Lucotte, Arnaud, Luehring, Fred, Luise, Ilaria, Lukianchuk, Oleksii, Lundberg, Olof, Lund-Jensen, Bengt, Luongo, Nicholas, Lutz, Margaret Susan, Lux, Adam Brayton, Lynn, David, Lyons, Harry John, Lysak, Roman, Lytken, Else, Lyubushkin, Vladimir, Lyubushkina, Tatiana, Lyukova, Mars, Ma, Hong, Ma, Kuo, Ma, Lianliang, Ma, Yanhui, Macdonell, Danika Marina, Maccarrone, Giovanni, Macdonald, Jack, Machado de Abreu Farias, Paulo Cesar, Madar, Romain, Mader, Wolfgang, Madula, Thandikire, Maeda, Junpei, Maeno, Tadashi, Maguire, Helen Ruth, Maiboroda, Vera, Maio, Amelia, Maj, Klaudia, Majersky, Oliver, Majewski, Stephanie, Makovec, Nikola, Maksimovic, Veljko, Malaescu, Bogdan, Malecki, Pawel, Maleev, Victor, Malek, Fairouz, Mali, Miha, Malito, Davide, Mallik, Usha, Maltezos, Stavros, Malyukov, Sergey, Mamuzic, Judita, Mancini, Giada, Manco, Giulia, Mandalia, Jesal, Mandic, Igor, Manhaes de Andrade Filho, Luciano, Maniatis, Ioannis 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Zekeriya, Vacavant, Laurent, Vacek, Vic, Vachon, Brigitte, Vadla, Knut Oddvar Hoie, Vafeiadis, Theodoros, Vaitkus, Andrius, Valderanis, Chrysostomos, Valdes Santurio, Eduardo, Valente, Marco, Valentinetti, Sara, Valero Biot, Alberto, Valiente Moreno, Enrique, Vallier, Alexis, Valls Ferrer, Juan, van Arneman, Dylan Remberto, van Daalen, Tal Roelof, van der Graaf, Aaron, van Gemmeren, Peter, van Rijnbach, Milou, van Stroud, Samuel, van Vulpen, Ivo, Vanadia, Marco, Vandelli, Wainer, Vandenbroucke, Maxence, van de Wall, Evan Richard, Vannicola, Damiano, Vannoli, Leonardo, Vari, Riccardo, Varnes, Erich Ward, Varni, Carlo, Mete, Tulin, Varouchas, Dimitris, Varriale, Lorenzo, Varvell, Kevin, Vasile, Matei, Vaslin, Louis, Vasquez, Gerardo, Vasyukov, Artem, Vazeille, Francois, Vazquez Schroeder, Tamara, Veatch, Jason Robert, Vecchio, Valentina, Veen, Michiel Jan, Veliscek, Iza, Veloce, Laurelle Maria, Veloso, Filipe, Veneziano, Stefano, Ventura, Andrea, Ventura Gonzalez, Salvador, Verbytskyi, 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Yamauchi, Hiroki, Yamazaki, Tomohiro, Yamazaki, Yuji, Yan, Jun, Yan, Siyuan, Yan, Zhen, Yang, Haijun, Yang, Hongtao, Yang, Siqi, Yang, Tianyi, Yang, Xiao, Yang, Xuan, Yang, Yi-Lin, Yang, Yifan, Yang, Zhe, Yao, Wei-Ming, Yap, Yee Chinn, Ye, Hanfei, Ye, Hua, Ye, Jingbo, Ye, Shuwei, Ye, Xinmeng, Yeh, Yoran, Yeletskikh, Ivan, Yeo, Beom Ki, Yexley, Melissa, Yin, Pengqi, Yorita, Kohei, Younas, Sulman, Young, Christopher, Young, Charlie, Yu, Chengjun, Yu, Yi, Yuan, Man, Yuan, Rui, Yue, Luzhan, Zaazoua, Mohamed, Zabinski, Bartlomiej Henryk, Zaid, Estifa'A, Zakareishvili, Tamar, Zakharchuk, Nataliia, Zambito, Stefano, Zamora Saa, Jilberto Antonio, Zang, Jiaqi, Zanzi, Daniele, Zaplatilek, Ota, Zeitnitz, Christian, Zeng, Hao, Zeng, Jiancong, Zenger, Todd, Zenin, Oleg, Zenis, Tibor, Zenz, Seth, Zerradi, Soufiane, Zerwas, Dirk, Zhai, Mingjie, Zhang, Bowen, Zhang, Dengfeng, Zhang, Jie, Zhang, Jinlong, Zhang, Kaili, Zhang, Lei, Zhang, Peng, Zhang, Rui, Zhang, Shuzhou, Zhang, Tingyu, Zhang, Xiangke, Zhang, Xueyao, Zhang, Yulei, Zhang, Yuwen Ebony, Zhang, Zhicai, Zhang, Zhiqing Philippe, Zhao, Haoran, Zhao, Pingchuan, Zhao, Tongbin, Zhao, Yuzhan, Zhao, Zhengguo, Zhemchugov, Alexey, Zheng, Jinchao, Zheng, Kai, Zheng, Xiangxuan, Zheng, Zhi, Zhong, Dewen, Zhou, Bing, Zhou, Hao, Zhou, Ning, Zhou, You, Zhu, Chengguang, Zhu, Junjie, Zhu, Yifan, Zhu, Yingchun, Zhuang, Xuai, Zhukov, Konstantin, Zhulanov, Vladimir, Zimine, Nikolai, Zinsser, Joachim, Ziolkowski, Michal, Zivkovic, Lidija, Zoccoli, Antonio, Zoch, Knut, Zorbas, Theodore, Zormpa, Olga, Zou, Wenkai, Zwalinski, Lukasz, Centre de Physique des Particules de Marseille (CPPM), Aix Marseille Université (AMU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'Annecy de Physique des Particules (LAPP), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique Subatomique et de Cosmologie (LPSC), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ), Université Grenoble Alpes (UGA), Laboratoire de Physique des 2 Infinis Irène Joliot-Curie (IJCLab), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE (UMR_7585)), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Laboratoire de Physique de Clermont (LPC), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université Clermont Auvergne (UCA), Laboratoire des deux Infinis de Toulouse (L2IT), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), and ATLAS

Subjects
p p: scattering, 13600 GeV-cms, final state: (4lepton), ATLAS, High Energy Physics - Experiment, Higgs particle: radiative decay, Higgs particle: hadroproduction, phase space, Higgs particle: branching ratio, total cross section: measured, CERN LHC Coll, kinematics, Z0: leptonic decay, Z0: pair production, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], photon: pair production, p p: colliding beams, channel cross section: measured, Higgs particle: decay modes, Particle Physics - Experiment, mass spectrum: two-photon, acceptance, experimental results
Abstract

The inclusive Higgs boson production cross-section is measured in the di-photon and the $ZZ^* \to 4 \ell$ decay channels using 31.4 and 29.0 fb$^{-1}$ of $pp$ collision data respectively, collected with the ATLAS detector at a centre-of-mass energy of $\sqrt{s}=13.6$ TeV. To reduce the model dependence, the measurement in each channel is restricted to a particle-level phase space that closely matches the channel's detector-level kinematic selection, and it is corrected for detector effects. These measured fiducial cross-sections are $\sigma_{\mathrm{fid},\gamma \gamma} = 76^{+14}_{-13}$ fb, and $\sigma_{\mathrm{fid},4 \ell} = 2.80 \pm 0.74$ fb, in agreement with the corresponding Standard Model predictions of $67.6 \pm 3.7 $ fb and $3.67 \pm 0.19 $ fb. Assuming Standard Model acceptances and branching fractions for the two channels, the fiducial measurements are extrapolated to the full phase space yielding total cross-sections of $\sigma(pp \to H) = 67^{+12}_{-11}$ pb and $46 \pm 12$ pb at $13.6$ TeV from the di-photon and $ZZ^* \to 4 \ell$ measurements respectively. The two measurements are combined into a total cross-section measurement of $\sigma(pp \to H)= 58.2 \pm 8.7$ pb, to be compared with the Standard Model prediction of $\sigma(pp \to H)_\mathrm{SM} = 59.9 \pm 2.6 $ pb., Comment: 51 pages in total, author list starting page 34, 3 figures, 7 tables, submitted to EPJC. All figures and tables including auxiliary figures and tables are available at https://atlas.web.cern.ch/Atlas/GROUPS/PHYSICS/PAPERS/HIGG-2022-12/

Published
2023

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