1. Late Outcomes of Transcatheter Aortic Valve Replacement in High-Risk Patients: The FRANCE-2 Registry
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Gilard, Martine, Eltchaninoff, Hélène, Donzeau Gouge, Patrick, Chevreul, Karine, Fajadet, Jean, Leprince, Pascal, Leguerrier, Alain, Lievre, Michel, Prat, Alain, Teiger, Emmanuel, Lefevre, Thierry, Tchetche, Didier, Didier, Didier, Himbert, Dominique, Albat, Bernard, Cribier, Alain, Sudre, Arnaud, Blanchard, Didier, Rioufol, Gilles, Collet, Frederic, Houel, Remi, Dos Santos, Pierre, Meneveau, Nicolas, Ghostine, Said, Manigold, Thibaut, Guyon, Philippe, Grisoli, Dominique, Le Breton, Herve, Delpine, Stephane, Favereau, Xavier, Souteyrand, Geraud, Ohlmann, Patrick, Doisy, Vincent, Grollier, Gilles, Gommeaux, Antoine, Claudel, Claude, Bourlon, Francois, Bertrand, Bernard, Laskar, Marc, Iung, Bernard, Bertrand, Michel, Cassagne, Jean, Boschat, Jacques, Lusson, Jean, Mathieu, Pierre, Logeais, Yves, Bessou, Jean-Paul, Chevalier, Bernard, Farge, Arnaud, Garot, Philippe, Hovasse, Thomas, Morice, Claude, Romano, Mauro, Vahdat, Olivier, Farah, Bruno, Carrie, Didier, Dumonteil, Nicolas, Fournial, Gérard, Bertrand, Marc, Nataf, Patrick, Vahanian, Alec, Leclercq, Florence, Piot, Christophe, Schmutz, Laurent, Aubas, Pierre, du Cailar, A., Dubar, A., Durrleman, N., Fargosz, F., Levy, Gilles, Maupas, Eric, Rivalland, François, Robert, G., Tron, Christophe, Juthier, Francis, Modine, Thomas, Van Belle, Eric, Banfi, Carlo, Sallerin, Thierry, Bar, Olivier, Barbey, Christophe, Chassaing, Stephan, Chatel, Didier, Le Page, Olivier, Tauran, Arnaud, Cao, Daniele, Dauphin, Raphael, Durand de Gevigney, Guy, Finet, Gérard, Jegaden, Olivier, Obadia, François, Beygui, Farzin, Collet, Jean-Philippe, Pavie, Alain, Vaillant, Alain, Vicat, Jacques, Wittenberg, Olivier, Joly, Patrick, Rosario, Roger, Bergeron, Patrice, Bille, Jacques, Gelisse, Richard, Couetil, Jean-Paul, Dubois Rande, Jean-Luc, Hayat, Delphine, Fougeres, Emilie, Monin, Jean-Luc, Mouillet, Gauthier, Arsac, Florence, Choukroun, Emmanuel, Dijos, Marina, Guibaud, Jean-Philippe, Leroux, Lionel, Elia, Nicolas, Chocron, Sidney, Schiele, François, Caussin, Christophe, Azmoun, Alexandre, Nottin, Rémi, Tirouvanziam, Ashok, Crochet, Dominique, Gaudin, Régis, Roussel, Jean-Christian, Bonnet, Nicolas, Digne, Franck, Mesnidrey, Patrick, Royer, Thierry, Stratiev, Victor, Bonnet, Jean-Louis, Cuisset, Thomas, Abouliatim, Issal, Bedossa, Marc, Boulmier, Dominique, Verhoye, Philippe, Delepine, Stéphane, Debrux, Jean-Louis, Furber, Alain, Pinaud, Frédéric, Bezon, Eric, Choplain, Jean-Noel, Bical, Oliver, Dambrin, Grégoire, Deleuze, Philippe, Jegou, Arnaud, Lusson, Jean-René, Azarnouch, Kasra, Durel, Nicolas, Innorta, Andrea, Lienhart, Yves, Roriz, Ricardo, Staat, Patrick, Fabiani, Jean-Noël, Lafont, Antoine, Zegdi, Rachid, Heudes, Didier, Kindo, Michel, Mazzucotelli, Jean-Philippe, Zupan, Michel, Ivascau, Calin, Lognone, Thérèse, Massetti, Massimo, Sabatier, Rémy, Huret, Bruno, Hochart, Philippe, Bouchayer, Damien, Gabrielle, François, Pelissier, Franck, Tremeau, Guillaume, Dreyfus, Gilles, Eker, Armand, Habib, Yakoub, Hugues, Nicolas, Mialhe, Claude, Chavanon, Olivier, Porcu, Paolo, Vanzetto, Gérald, Donzeau-Gouge, Patrick, Didier, Romain, Gommeaux, Bernard, Claudel, Jean-Philippe, Nutrition, obésité et risque thrombotique ( NORT ), Institut National de la Recherche Agronomique ( INRA ) -Aix Marseille Université ( AMU ) -Institut National de la Santé et de la Recherche Médicale ( INSERM ), Nutrition, obésité et risque thrombotique (NORT), Aix Marseille Université (AMU)-Institut National de la Recherche Agronomique (INRA)-Institut National de la Santé et de la Recherche Médicale (INSERM), and Institut National de la Recherche Agronomique (INRA)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)
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[SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system ,predictive analysis ,aortic stenosis ,risk score ,[ SDV.MHEP.CSC ] Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system - Abstract
International audience; Transcatheter aortic valve replacement (TAVR) has revolutionized management of high-risk patients with severe aortic stenosis. However, survival and the incidence of severe complications have been assessed in relatively small populations and/or with limited follow-up.; This report details late clinical outcome and its determinants in the FRANCE-2 (FRench Aortic National CoreValve and Edwards) registry.; The FRANCE-2 registry prospectively included all TAVRs performed in France. Follow-up was scheduled at 30 days, at 6 months, and annually from 1 to 5 years. Standardized VARC (Valve Academic Research Consortium) outcome definitions were used.; A total of 4,201 patients were enrolled between January 2010 and January 2012 in 34 centers. Approaches were transarterial (transfemoral 73%, transapical 18%, subclavian 6%, and transaortic or transcarotid 3%) or, in 18% of patients, transapical. Median follow-up was 3.8 years. Vital status was available for 97.2% of patients at 3 years. The 3-year all-cause mortality was 42.0% and cardiovascular mortality was 17.5%. In a multivariate model, predictors of 3-year all-cause mortality were male sex (p < 0.001), low body mass index, (p < 0.001), atrial fibrillation (p < 0.001), dialysis (p < 0.001), New York Heart Association functional class III or IV (p < 0.001), higher logistic EuroSCORE (p
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- 2016