Search

Your search keyword '"HYPOKALEMIA – therapy"' showing total 2 results
Start Over Descriptor "HYPOKALEMIA – therapy"
2 results on '"HYPOKALEMIA – therapy"'

1. Understanding, prevention and treatment of refeeding syndrome. The role of thiamine

Author

Dina Ljubas Kelečić, Darija Vranešić Bender, and Željko Krznarić

Subjects
refeeding syndrome – complications, physiopathology, prevention and control, therapy, malnutrition – metabolism, nutritional support – adverse effects, hypophosphatemia – complications, etiology, thiamine – physiology, therapeutic use, thiamine deficiency – complications, magnesium deficiency – therapy, hypokalemia – therapy, wernicke encephalopathy – etiology, Medicine (General), R5-920
Abstract

Refeeding syndrome (RFS) is a serious and potentially fatal complication that occurs in patients with severe malnutrition of various etiologies after repeated, uncontrolled introduction of a diet, especially carbohydrates. Complications of RFS develop due to rapid metabolic changes that occur during the switch from catabolism to anabolism, and cellular depletion of phosphorus, potassium, magnesium and micronutrients, and can affect one or more organ systems. Most of RFS complications associated with vitamin deficiency are related to thiamine deficiency. Due to its coenzyme role in the metabolism of carbohydrates and branched chain amino acids, thiamine is an important factor in maintaining the normal function primarily of cerebral energy metabolism. Understanding the basic biochemistry during starvation, and consequently the mechanisms and factors influencing metabolic changes during RFS, is important for timely identification of patients at risk and prevention of RFS and also many clinical complications it can cause regardless of nutritional support modality.

Published
2021
Full Text
View/download PDF

2. Razumijevanje, prevencija i liječenje refeeding-sindroma: uloga tiamina

Author

Dina Ljubas Kelečić, Darija Vranešić Bender, and Željko Krznarić

Subjects
WERNICKE ENCEPHALOPATHY – etiology, physiopathology, therapy, EFEEDING SYNDROME – complications, physiopathology, prevention and control, therapy, THIAMINE DEFICIENCY – complications, etiology, therapy, MALNUTRITION – metabolism, therapy, realimentacijski sindrom – komplikacije, liječenje, patofiziologija, prevencija, malnutricija – liječenje, metabolizam, nutritivna potpora – neželjeni učinci, hipofosfatemija – etiologija, komplikacije, liječenje, tiamin – fiziologija, terapijska uporaba, nedostatak tiamina – etiologija, komplikacije, liječenje, nedostatak magnezija – liječenje, hipokalemija – liječenje, wernickeova encefalopatija –etiologija, liječenje, patofiziologija, THIAMINE – physiology, therapeutic use, NUTRITIONAL SUPPORT – adverse effects, MAGNESIUM DEFICIENCY – therapy, Deskriptori REALIMENTACIJSKI SINDROM – komplikacije, liječenje, patofiziologija, prevencija, MALNUTRICIJA – liječenje, metabolizam, NUTRITIVNA POTPORA – neželjeni učinci, HIPOFOSFATEMIJA – etiologija, komplikacije, liječenje, TIAMIN – fiziologija, terapijska uporaba, NEDOSTATAK TIAMINA – etiologija, komplikacije, liječenje, NEDOSTATAK MAGNEZIJA – liječenje, HIPOKALEMIJA – liječenje, WERNICKEOVA ENCEFALOPATIJA –etiologija, liječenje, patofiziologija, HYPOKALEMIA – therapy, HYPOPHOSPHATEMIA – complications, etiology, therapy
Abstract

Refeeding-sindrom (RFS) je ozbiljna i potencijalno fatalna komplikacija koja se javlja u bolesnika s ozbiljnom pothranjenosti različite etiologije nakon ponovnog, nekontroliranog uvođenja prehrane, osobito ugljikohidrata. Nastanak komplikacija RFS-a, koje mogu zahvatiti bilo koji organski sustav ili više njih uslijed ozbiljnog elektrolitskog disbalansa, uvjetovan je brzim metaboličkim promjenama koje nastaju prilikom prelaska organizma iz katabolizma u anabolizam te unutarstaničnom deplecijom fosfora, kalija, magnezija te vitamina i mineralnih tvari. Najčešće komplikacije RFS-a vezane uz nedostatak vitamina odnose se na nedostatak tiamina. Zbog svoje ključne koenzimske uloge u metabolizmu ugljikohidrata i aminokiselina razgranatih lanaca, tiamin je važan čimbenik za održavanje normalne funkcije prije svega cerebralnog metabolizma. Razumijevanje temeljnih biokemijskih procesa tijekom gladovanja te posljedično mehanizama i čimbenika koji utječu na metaboličke promjene tijekom RFS-a važno je radi pravovremenog prepoznavanja bolesnika u riziku i prevencije RFS-a te brojnih kliničkih komplikacija koje nosi bez obzira na modalitet nutritivne potpore., Refeeding syndrome (RFS) is a serious and potentially fatal complication that occurs in patients with severe malnutrition of various etiologies after repeated, uncontrolled introduction of a diet, especially carbohydrates. Complications of RFS develop due to rapid metabolic changes that occur during the switch from catabolism to anabolism, and cellular depletion of phosphorus, potassium, magnesium and micronutrients, and can affect one or more organ systems. Most of RFS complications associated with vitamin deficiency are related to thiamine deficiency. Due to its coenzyme role in the metabolism of carbohydrates and branched chain amino acids, thiamine is an important factor in maintaining the normal function primarily of cerebral energy metabolism. Understanding the basic biochemistry during starvation, and consequently the mechanisms and factors influencing metabolic changes during RFS, is important for timely identification of patients at risk and prevention of RFS and also many clinical complications it can cause regardless of nutritional support modality.

Published
2021

Catalog

Books, media, physical & digital resources
See catalog results