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1. STING agonist 8803 reprograms the immune microenvironment and increases survival in preclinical models of glioblastoma

Author

Najem, Hinda, Lea, Spencer T., Tripathi, Shashwat, Hurley, Lisa, Chen, Chao- Hsien, William, Ivana, Sooreshjani, Moloud, Bowie, Michelle, Hartley, Genevieve, Dussold, Corey, Pacheco, Sebastian, Dmello, Crismita, Lee-Chang, Catalina, McCortney, Kathleen, Steffens, Alicia, Walshon, Jordain, Martina Ot, Wei, Jun, Marisetty, Anantha, Balyasnikova, Irina, Stupp, Roger, Lukas, Rimas V., Hu, Jian, James, Charles David, Horbinski, Craig M., Lesniak, Maciej S., Ashley, David M., Priebe, Waldemar, Platanias, Leonidas C., Curran, Michael A., and Heimberger, Amy B.

Subjects
Oncology, Experimental, Agonists (Biochemistry) -- Research, Gene expression -- Research, Immune response -- Genetic aspects -- Health aspects, Glioblastoma multiforme -- Care and treatment -- Drug therapy -- Genetic aspects -- Models, Cancer -- Research, Health care industry
Abstract

STING agonists can reprogram the tumor microenvironment to induce immunological clearance within the central nervous system. Using multiplexed sequential immunofluorescence (SeqIF) and the Ivy Glioblastoma Atlas, STING expression was found in myeloid populations and in the perivascular space. The STING agonist 8803 increased median survival in multiple preclinical models of glioblastoma, including QPP8, an immune checkpoint blockade-resistant model, where 100% of mice were cured. Ex vivo flow cytometry profiling during the therapeutic window demonstrated increases in myeloid tumor trafficking and activation, alongside enhancement of [CD8.sup.+] T cell and NK effector responses. Treatment with 8803 reprogrammed microglia to express costimulatory CD80/CD86 and iNOS, while decreasing immunosuppressive CD206 and arginase. In humanized mice, where tumor cell STING is epigenetically silenced, 8803 therapeutic activity was maintained, further attesting to myeloid dependency and reprogramming. Although the combination with a STAT3 inhibitor did not further enhance STING agonist activity, the addition of anti-PD-1 antibodies to 8803 treatment enhanced survival in an immune checkpoint blockade-responsive glioma model. In summary, 8803 as a monotherapy demonstrates marked in vivo therapeutic activity, meriting consideration for clinical translation., Introduction The prognosis of glioblastoma patients is poor, with an approximate median overall survival of 21 months (1). Whereas radiation and chemotherapy are standard treatments at the time of diagnosis, [...]

Published
2024
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2. A first-in-human phase 0 clinical study of RNA interference-based spherical nucleic acids in patients with recurrent glioblastoma.

Author

Kumthekar, Priya, Ko, Caroline H, Paunesku, Tatjana, Dixit, Karan, Sonabend, Adam M, Bloch, Orin, Tate, Matthew, Schwartz, Margaret, Zuckerman, Laura, Lezon, Ray, Lukas, Rimas V, Jovanovic, Borko, McCortney, Kathleen, Colman, Howard, Chen, Si, Lai, Barry, Antipova, Olga, Deng, Junjing, Li, Luxi, Tommasini-Ghelfi, Serena, Hurley, Lisa A, Unruh, Dusten, Sharma, Nitya V, Kandpal, Manoj, Kouri, Fotini M, Davuluri, Ramana V, Brat, Daniel J, Muzzio, Miguel, Glass, Mitchell, Vijayakumar, Vinod, Heidel, Jeremy, Giles, Francis J, Adams, Ann K, James, C David, Woloschak, Gayle E, Horbinski, Craig, and Stegh, Alexander H

Subjects
Humans, Glioblastoma, Brain Neoplasms, Neoplasm Recurrence, Local, Gold, Muscle Proteins, Proto-Oncogene Proteins c-bcl-2, Nucleic Acids, RNA Interference, Metal Nanoparticles, Brain Cancer, Gene Therapy, Cancer, Neurosciences, Bioengineering, Rare Diseases, Nanotechnology, Biotechnology, Genetics, Brain Disorders, Evaluation of treatments and therapeutic interventions, 6.1 Pharmaceuticals, Good Health and Well Being, Biological Sciences, Medical and Health Sciences
Abstract

Glioblastoma (GBM) is one of the most difficult cancers to effectively treat, in part because of the lack of precision therapies and limited therapeutic access to intracranial tumor sites due to the presence of the blood-brain and blood-tumor barriers. We have developed a precision medicine approach for GBM treatment that involves the use of brain-penetrant RNA interference-based spherical nucleic acids (SNAs), which consist of gold nanoparticle cores covalently conjugated with radially oriented and densely packed small interfering RNA (siRNA) oligonucleotides. On the basis of previous preclinical evaluation, we conducted toxicology and toxicokinetic studies in nonhuman primates and a single-arm, open-label phase 0 first-in-human trial (NCT03020017) to determine safety, pharmacokinetics, intratumoral accumulation and gene-suppressive activity of systemically administered SNAs carrying siRNA specific for the GBM oncogene Bcl2Like12 (Bcl2L12). Patients with recurrent GBM were treated with intravenous administration of siBcl2L12-SNAs (drug moniker: NU-0129), at a dose corresponding to 1/50th of the no-observed-adverse-event level, followed by tumor resection. Safety assessment revealed no grade 4 or 5 treatment-related toxicities. Inductively coupled plasma mass spectrometry, x-ray fluorescence microscopy, and silver staining of resected GBM tissue demonstrated that intravenously administered SNAs reached patient tumors, with gold enrichment observed in the tumor-associated endothelium, macrophages, and tumor cells. NU-0129 uptake into glioma cells correlated with a reduction in tumor-associated Bcl2L12 protein expression, as indicated by comparison of matched primary tumor and NU-0129-treated recurrent tumor. Our results establish SNA nanoconjugates as a potential brain-penetrant precision medicine approach for the systemic treatment of GBM.

Published
2021

3. Corrigendum: miR-182 integrates apoptosis, growth, and differentiation programs in glioblastoma

Author

Kouri, Fotini M., primary, Hurley, Lisa A., additional, Daniel, Weston L., additional, Day, Emily S., additional, Hua, Youjia, additional, Hao, Liangliang, additional, Peng, Chian-Yu, additional, Merkel, Timothy J., additional, Queisser, Markus A., additional, Ritner, Carissa, additional, Zhang, Hailei, additional, James, C. David, additional, Sznajder, Jacob I., additional, Chin, Lynda, additional, Giljohann, David A., additional, Kessler, John A., additional, Peter, Marcus E., additional, Mirkin, Chad A., additional, and Stegh, Alexander H., additional

Published
2024
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4. The RIO trial: rationale, design, and the role of community involvement in a randomised placebo-controlled trial of antiretroviral therapy plus dual long-acting HIV-specific broadly neutralising antibodies (bNAbs) in participants diagnosed with recent HIV infection—study protocol for a two-stage randomised phase II trial

Author

Lee, Ming Jie, Collins, Simon, Babalis, Daphne, Johnson, Nicholas, Falaschetti, Emanuela, Prevost, A. Toby, Ashraf, Ambreen, Jacob, Milaana, Cole, Tom, Hurley, Lisa, Pace, Matthew, Ogbe, Ane, Khan, Maryam, Zacharopoulou, Panagiota, Brown, Helen, Sutherland, Euan, Box, Hanna, Fox, Julie, Deeks, Steven, Horowitz, Jill, Nussenzweig, Michel C., Caskey, Marina, Frater, John, and Fidler, Sarah

Published
2022
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5. Spherical Nucleic Acid Nanoparticle Conjugates as an RNAi-Based Therapy for Glioblastoma*

Author

Jensen, Samuel A., primary, Day, Emily S., additional, Ko, Caroline H., additional, Hurley, Lisa A., additional, Luciano, Janina P., additional, Kouri, Fotini M., additional, Merkel, Timothy J., additional, Luthi, Andrea J., additional, Patel, Pinal C., additional, Cutler, Joshua I., additional, Daniel, Weston L., additional, Scott, Alexander W., additional, Rotz, Matthew W., additional, Meade, Thomas J., additional, Giljohann, David A., additional, Mirkin, Chad A., additional, and Stegh, Alexander H., additional

Published
2020
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6. Adjunctive rifampicin for Staphylococcus aureus bacteraemia (ARREST): a multicentre, randomised, double-blind, placebo-controlled trial

Author

Scarborough, Matthew, Kamfose, Musa, de Veciana, Ana, Gordon, Nicola Claire, Peto, Leon, Pill, Gemma, Clarke, Tiphanie, Watson, Laura, Young, Bernadette, Griffiths, Dai, Vaughn, Ali, Anson, Luke, Liu, Elian, Perera, Sanuki, Rylance-Knight, Lydia, Cantell, Carmen, Moroney, Ruth, Edgeworth, Jonathan D, Thwaites, Guy, Bisnauthsing, Karen, Querol-Rubiera, Antonio, Gibbs, Charlotte, Patel, Amita, Hemsley, Carolyn, Goodman, Anna L, Wyncoll, Duncan, Biswas, Jason, Fitzpatrick, Jennifer, Roberts, Lizzie, Millard, James, Stone, Neil, Cape, Angela, Hurley, Lisa, Tam, Chi Kai, Nsutebu, Emmanuel, Hoyle, Marie-Claire, Maitland, Kate, Trainor, Leona, Reynolds, Helen, Harrison, Jennifer, Anson, Jim, Lewis, Joseph, Folb, Jonathan, Goodwin, Lynsey, Beeching, Nicholas, Dyas, Sarah, Winslow, Helen, Foote, Elizabeth, Roberts, Paul, Natarajan, Pavithra, Chrdle, Alex, Fenech, Manuel, Allsop, Hannah, Tilley, Robert, Austin-Hutchison, Rachel, Barrett, Louise, Brookes, Karen, Carwithen, Leanne, Conbeer, Andrew, Cunningham, Richard, Eglinton, Charlotte, Fok, Rosie, Gott, Hannah, Hughes, Shona, Jones, Lewis, Kalita, Maggie, King, Angela, March, Linda, Marner, Mike, Mynes, Tracey, Plant, Aiden, Price, Suzanne, Sercombe, Judy, Stolton, Alison, Wallis, Mark, West, Marie-Claire, Westcott, Jackie, Williams, Claire, Wosley, Rob, Yabsley, Leona, Greig, Julia, Butland, Laura, Sorrell, Julie, Mitchell, Tamara, Alli, Abiola, Meiring, James, Masake, Boingotlo, Rowson, Carlene, Smart, Lynne, Makey, Laura, Moll, Sarah, Cunningham, Jane, Ryalls, Kim, Birchall, Kathryn, Middle, Janet, Jackson, Yvonne, Swift, Diane, Cole, Joby, Subramanian, Bala, Okhuoya, Faith, Edwards, Maria, Bailey, Cheryl, Warren, Rebecca, Islam, Gayti, Ankcorn, Michael, Birchall, Sarah, Jones, Paul, Humphries, John, Booth, Stephen, Evan, Cariad, Wyllie, Sarah, Flatt, Andrew, Strakova, Lenka, Hayes, Maria, Valentine, Stacey, James, Clare, Wands, Mary, Cortes, Nicolas, Khan, Nisa, Porter, Robert, Martin, Zoe, Yip, Keith, Preedy, Helen, Chesterfield, Helen, Dobson, Tracey, Walker, Colin, Llewelyn, Martin, Dunne, Angela, Latter, Laura, Porges, Alison, Price, James, Paul, John, Behar, Laura, Robinson, Louise, Murray, Amy, Sargent, Tenessa, Ridley, Carrie, de Gordoa, Laura Ortiz-Ruiz, Gilliam, Deborah, McPherson, Carole, Matthews, Simon, Foreman, Emma, Jarghese, Rajesh, Beddoe, Alisha, Martin, Sebastien, Shaw, Sephora, Wlazly, Dominika, Cole, Maggie, Gihawi, Abraham, Cole, Kevin, Török, M Estée, Gouliouris, Theodore, Bedford, Luke, Saunderson, Rebecca B, Mariolis, Ilias, Bousfield, Rachel, Ramsay, Isobel, Greaves, Daniel, Aliyu, Sani, Cox, Kim, Mlemba, Lois, Whitehead, Lynne, Vyse, Naval, Bolton, Mark, Williams, John, Lambert, Pauline, Chadwick, David, Baillie, Kirsty, Cain, Martyn, Bellamy, Richard, Wong, Jason, Thompson, Jane, Vassallo, Helen, Skotnicka, Agnieszka, Boyce, Andrea, Donnelly, Anthony, Wilson, Peter, FitzGerald, Graham, Dean, Victoria, Warnes, Kristian, Reyes, Anna, Rahman, Saadia, Tsang, Lillian, Williams, Joanne, Morris-Jones, Stephen, Hopkins, Susan, Witness, Elen, Brady, Orla, Woodford, Elizabeth, Pettifer, Teresa, McCadden, Angela, Marks, Ben, Collier, Sophie, Mack, Damien, Warren, Simon, Brown, Colin, Lyons, Adrian, Taiyari, Sara, Mepham, Stephen, Sweeney, Anna, Brown, Li-An, Auckland, Cressida, Potter, Alison, Mandiza, Jess, Hough, Maxine, Williams, Sue, Renton, Caroline, Walters, Fiona, Nadolski, Maria, Evans, Andree, Tarrant, Polly, Curley, Katherine, Whiteley, Sophie, Halpin, Julia, Hutchings, Melanie, Todd, Shirley, Lohan, Christop, Chapter, Tamika, Folland, Emma, Colville, Alaric, Marden, Katy, Morgan, Marina, Porter, Rob, Baxter, Mel, Minton, Jane, Rippon, Sarah, Cevik, Muge, Chapman, Judith, Kemp, Tim, Vincent, Rachel, Osborne, Dave, Platt, Tracey, Calderwood, James, Cook, Bernadette, Bedford, Caroline, Galloway-Browne, Leanne, Abberley, Nadine, Attack, Kelly, Allen, Joanna, Lal, Pankaj, Harrison, Melanie, Stevenson, Sarah, Brooks, Carol, Harlow, Paula, Ewing, Jordan, Cooper, Shirley, Balancio-Tolentino, Roderick, O'Neil, Laura, Tagney, Rebecca, Shackcloth, Daniela, Planche, Tim, Fellows, James, Millett, Ruth, Studham, Jo, de Souza, Cherrelle, Howell, Geoffrey, Greaves, Hezron, Foncel, Ella, Kurup, Rahul, Briggs, Jack, Smith, Melody, Suarez, Cristina, Sorrentino, Giordana, Scobie, Antonia, Houston, Angela, Ahmad, Fozia, Breathnach, Aodhan, Chahuan, Rakhee, Wilkins, Katie, Guleri, Achyut, Waddington, Natalia, Sharma, Rashmi, Flegg, Peter, Kollipara, Veenu, Alam, Mazhar, Potter, Andrew, Donaldson, Stacey, Armer, Charlote, Frudd, Julie, Jeyaratnam, Dakshika, Joy, Manju, Mathews, Asha, Glass, Stephen K, Ajayi, Ayodele, Fife, Amanda, Qaiser, Saba, Sheehan, Sharon, Muñoz-Villaverde, Sergio, Yogo, Noah, De Abreu, Ines, Notcheva, Gaynor, Flanagan, Joanna, Watson, Cordelia, Sais, Efisia, Adedayo, Adetunji, Chu, Vicky, Shaw, Georgina, Graver, Michelle A, Palmer, Rebecca, Palmer, Donna, Haile, Senait, Gordon, Joanne, Mandar, Kirandip, Szypura, Weronika, Jenkins, Neil, Marange, Josephine, Shabangu, Vusumuzi, Moore, Katy, Lyons, Jill, Munang, Melinda, Sangombe, Mirriam, Moran, Ed, Hussain, Abid, Wiselka, Martin, Lewszuk, Adam, Batham, Sally, Ellis, Kate, Bahadur, Leila, White, Helena, Pareek, Manish, Sahota, Amandip, Coleman, Stephen, Pateman, Hilary, Kotecha, Atul, Sim, Christopher, Rosser, Andrew, Deane, Jill, Nendick, Richard, Aldridge, Catherine, Clarke, Anne, Wood, Michelle, Marshall, Adele, Stephenson, Lynsey, Matheson-Smith, Tracy, Sloss, John, Potts, Kathryn, Malkin, Joanne, Ftika, Lemonia, Raviprakash, Veena, Sutton, Julian, Malachira, Ahalya, Kean, Miranda, Criste, Kristine, Gladas, Kirsty, Andrews, Caroline, Hutchison, Clare, Adams, Ellen, Andrews, Janet, Romans, Belinda, Ridley, Nicola, Ekani, Melanie, Mitchell, Julie, Smith, Nicola, Clark, Tristan, Glover, Sarah, Reed, Robert, Yam, Tat, Burton, Holly, Said, Rasha, Harvey, David, Janvier, Amy, Jacob, Reni, Smalley, Chris, Fair, Alison, Lord, Susan, Ripalda, Kate, Wooldridge, Helen, Cotter, Luis, Cardoso, Gus, Strachan, Elaine, Kaler, Gagan, Mohamoodally, Adam, Lawrence, Emma, Prime, Zoe, Abrahams, Rachel, Price, David Ashley, Rigden, Lesley, Shewan, Laura, Cullen, Katherine, Emmerson, Ingrid, Martin, Karen, Wilson, Hesther, Higham, Charley, Taylor, Kathryn Louise, Ong, Edmund, Patel, Bijal, Bond, Helena, Gradwell, Janine, Widdrington, John, Graham, Clive, Thornthwaite, Sarah, Prentice, Scott, Poultney, Una, Crowther, Hannah, Fairlamb, Helen, Hetherington, Emily, Brewer, Chris, Banerjee, Suryabrata, Hamson, Clare, McSkeane, Anna, McWhinney, Paul, Sharratt, Paula, Thorpe, Joanne, Kimachia, Sue, Wilson, Helen, Jeffs, Benjamin, Masters, Leslie, Wilson, Jonathan, Platt, Judith, Burgess, Lisa, Chadwick, Paul, Jeans, Adam, Keatley, Claire, Moran, Amanda, Swann, Zoe, Pagett, Katherine, Peel, Alex, Howard, Jason, Meisner, Sarah, Maloney, Kate, Masdin, Avril, Wright, Louise, Barlow, Gavin, Crossman, Samantha, Lowthorpe, Vicki, Moore, Emma, Moss, Peter, Parkin, Angela, Wolstencroft, Adam, Warner, Bev, Tarbotton, Clare, Eyre, Alison, Anderson, Anne, Burdett, Tina, Driffill, Amy, Walker, Ann Sarah, Hudson, Fleur, Szubert, Alex, Cairns, Janet, Ward, Denise, Webb, Helen, Russell, Charlotte, Jackson, Brooke, Otiko, Damilola, Borg, Chiara, Masters, Lindsey, Islam, Zaheer, Díaz-Montaña, Carlos, Johnson, Debbie, Thwaites, Guy E, Szubert, Alexander, Wyllie, Sarah A, Armando, Gonzalez-Ruiz, Chadwick, Paul R, Gordon, N Claire, Price, David A, Nayar, Deepa, Török, M Estee, Llewelyn, Martin J, and Walker, A Sarah

Published
2018
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9. Abstract LB335: Establishment of the effective dose of the STAT3 inhibitor WP1066 used in combination with STING activation for reprograming the preclinical glioma microenvironment

Author

Najem, Hinda, primary, Tripathi, Shashwat, additional, Sooreshjani, Moloud, additional, Hurley, Lisa, additional, Dussold, Corey, additional, Arrieta, Victor, additional, Ott, Martina, additional, Wei, Jun, additional, Curran, Michael, additional, Marisetty, Anantha, additional, Priebe, Waldemar, additional, Platanias, Leondias C., additional, Lesniak, Maciej S., additional, James, Charles D., additional, Horbinski, Craig, additional, Ashley, David M., additional, and Heimberger, Amy B., additional

Published
2023
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10. The effect of TRV027 on coagulation in COVID‐19: A pilot randomized, placebo‐controlled trial

Author

Robbins, Alexander J., primary, Che Bakri, Nur Amalina, additional, Toke‐Bjolgerud, Edward, additional, Edwards, Aaron, additional, Vikraman, Asha, additional, Michalsky, Cathy, additional, Fossler, Michael, additional, Lemm, Nana‐Marie, additional, Medhipour, Savviz, additional, Budd, William, additional, Gravani, Athanasia, additional, Hurley, Lisa, additional, Kapil, Vikas, additional, Jackson, Aimee, additional, Lonsdale, Dagan, additional, Latham, Victoria, additional, Laffan, Michael, additional, Chapman, Neil, additional, Cooper, Nichola, additional, Szydlo, Richard, additional, Boyle, Joseph, additional, Pollock, Katrina M., additional, and Owen, David, additional

Published
2022
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12. The effect of TRV027 on coagulation in COVID-19: A pilot randomized, placebo-controlled trial.

Author

Robbins, Alexander J., Che Bakri, Nur Amalina, Toke-Bjolgerud, Edward, Edwards, Aaron, Vikraman, Asha, Michalsky, Cathy, Fossler, Michael, Lemm, Nana-Marie, Medhipour, Savviz, Budd, William, Gravani, Athanasia, Hurley, Lisa, Kapil, Vikas, Jackson, Aimee, Lonsdale, Dagan, Latham, Victoria, Laffan, Michael, Chapman, Neil, Cooper, Nichola, and Szydlo, Richard

Subjects
ANGIOTENSIN converting enzyme, COVID-19, EXPERIMENTAL medicine, BLOOD coagulation, BAYESIAN analysis, ANGIOTENSIN II, CYCLOSERINE
Abstract

COVID-19 causes significant thrombosis and coagulopathy, with elevated D-dimer a predictor of adverse outcome. The precise mechanism of this coagulopathy remains unclear; one hypothesis is that loss of angiotensin-converting enzyme 2 activity during viral endocytosis leads to pro-inflammatory angiotensin-II accumulation, loss of angiotensin-1-7 and subsequent vascular endothelial activation. We undertook a double-blind randomized, placebo-controlled experimental medicine study to assess the effect of TRV027, a synthetic angiotensin-1-7 analogue on D-dimer in 30 patients admitted to hospital with COVID-19. The study showed a similar rate of adverse events in TRV027 and control groups. There was a numerical decrease in D-dimer in the TRV027 group and increase in D-dimer in the placebo group; however, this did not reach statistical significance (P = .15). A Bayesian analysis demonstrated that there was a 92% probability that this change represented a true drug effect. [ABSTRACT FROM AUTHOR]

Published
2023
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13. Additional file 4 of The RIO trial: rationale, design, and the role of community involvement in a randomised placebo-controlled trial of antiretroviral therapy plus dual long-acting HIV-specific broadly neutralising antibodies (bNAbs) in participants diagnosed with recent HIV infection—study protocol for a two-stage randomised phase II trial

Author

Lee, Ming Jie, Collins, Simon, Babalis, Daphne, Johnson, Nicholas, Falaschetti, Emanuela, Prevost, A. Toby, Ashraf, Ambreen, Jacob, Milaana, Cole, Tom, Hurley, Lisa, Pace, Matthew, Ogbe, Ane, Khan, Maryam, Zacharopoulou, Panagiota, Brown, Helen, Sutherland, Euan, Box, Hanna, Fox, Julie, Deeks, Steven, Horowitz, Jill, Nussenzweig, Michel C., Caskey, Marina, Frater, John, and Fidler, Sarah

Subjects
Data_FILES
Abstract

Additional file 4.

Published
2022
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14. Additional file 3 of The RIO trial: rationale, design, and the role of community involvement in a randomised placebo-controlled trial of antiretroviral therapy plus dual long-acting HIV-specific broadly neutralising antibodies (bNAbs) in participants diagnosed with recent HIV infection—study protocol for a two-stage randomised phase II trial

Author

Lee, Ming Jie, Collins, Simon, Babalis, Daphne, Johnson, Nicholas, Falaschetti, Emanuela, Prevost, A. Toby, Ashraf, Ambreen, Jacob, Milaana, Cole, Tom, Hurley, Lisa, Pace, Matthew, Ogbe, Ane, Khan, Maryam, Zacharopoulou, Panagiota, Brown, Helen, Sutherland, Euan, Box, Hanna, Fox, Julie, Deeks, Steven, Horowitz, Jill, Nussenzweig, Michel C., Caskey, Marina, Frater, John, and Fidler, Sarah

Subjects
Data_FILES
Abstract

Additional file 3.

Published
2022
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15. Additional file 2 of The RIO trial: rationale, design, and the role of community involvement in a randomised placebo-controlled trial of antiretroviral therapy plus dual long-acting HIV-specific broadly neutralising antibodies (bNAbs) in participants diagnosed with recent HIV infection—study protocol for a two-stage randomised phase II trial

Author

Lee, Ming Jie, Collins, Simon, Babalis, Daphne, Johnson, Nicholas, Falaschetti, Emanuela, Prevost, A. Toby, Ashraf, Ambreen, Jacob, Milaana, Cole, Tom, Hurley, Lisa, Pace, Matthew, Ogbe, Ane, Khan, Maryam, Zacharopoulou, Panagiota, Brown, Helen, Sutherland, Euan, Box, Hanna, Fox, Julie, Deeks, Steven, Horowitz, Jill, Nussenzweig, Michel C., Caskey, Marina, Frater, John, and Fidler, Sarah

Subjects
Data_FILES
Abstract

Additional file 2.

Published
2022
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16. Additional file 1 of The RIO trial: rationale, design, and the role of community involvement in a randomised placebo-controlled trial of antiretroviral therapy plus dual long-acting HIV-specific broadly neutralising antibodies (bNAbs) in participants diagnosed with recent HIV infection—study protocol for a two-stage randomised phase II trial

Author

Lee, Ming Jie, Collins, Simon, Babalis, Daphne, Johnson, Nicholas, Falaschetti, Emanuela, Prevost, A. Toby, Ashraf, Ambreen, Jacob, Milaana, Cole, Tom, Hurley, Lisa, Pace, Matthew, Ogbe, Ane, Khan, Maryam, Zacharopoulou, Panagiota, Brown, Helen, Sutherland, Euan, Box, Hanna, Fox, Julie, Deeks, Steven, Horowitz, Jill, Nussenzweig, Michel C., Caskey, Marina, Frater, John, and Fidler, Sarah

Subjects
Data_FILES
Abstract

Additional file 1.

Published
2022
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21. The RIO Trial: Rationale, Design, And The Role of Community Involvement In A Randomised Placebo-Controlled Trial of Antiretroviral Therapy Plus Dual Long-Acting HIV-Specific Broadly Neutralising Antibodies (bNAbs) In Participants Diagnosed With Recent HIV Infection - Study Protocol For A Two-Stage Randomised Phase II Trial

Author

Lee, Ming Jie, primary, Collins, Simon, additional, Babalis, Daphne, additional, Johnson, Nicholas, additional, Falaschetti, Emanuela, additional, Prevost, A Toby, additional, Ashraf, Ambreen, additional, Cole, Tom, additional, Hurley, Lisa, additional, Pace, Matthew, additional, Ogbe, Ane, additional, Khan, Maryam, additional, Zacharopoulou, Panagiota, additional, Brown, Helen, additional, Box, Hanna, additional, Fox, Julie, additional, Deeks, Steven, additional, Horowitz, Jill, additional, Nussenzweig, Michel C, additional, Caskey, Marina, additional, Frater, John, additional, and Fidler, Sarah, additional

Published
2021
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27. Sox3 expression in undifferentiated spermatogonia is required for the progression of spermatogenesis

Author

Raverot, Gerald, Weiss, Jeffrey, Park, Susan Y., Hurley, Lisa, and Jameson, J. Larry

Subjects
Testosterone, Biological sciences
Abstract

To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.ydbio.2005.04.013 Byline: Gerald Raverot, Jeffrey Weiss, Susan Y. Park, Lisa Hurley, J. Larry Jameson Abstract: Sox3, a member of the high mobility group (HMG) family of transcription factors, is expressed in neural progenitor cells and in the gonads. Targeted deletion of Sox3 in mice causes abnormal development of the diencephalon and Rathke's pouch, the progenitor of the anterior pituitary gland. Male and female mice are also infertile and exhibit a primary defect in gametogenesis. In this study, we examined the expression and function of Sox3 in C57BL/6 mice to better understand its role in spermatogenesis. Testis development was normal during embryogenesis. However, spermatogenesis failed to progress during the postnatal period, with germ cell loss beginning at postnatal day 10 (P10). By P14, Sox3 null mice were nearly agametic, retaining only Sertoli cells and undifferentiated spermatogonia. Pituitary gonadotropin and testosterone levels were normal, suggesting a defect in Sertoli cell and/or germ cell function. Immunostaining revealed that Sox3 was expressed in a subpopulation of germ cells localized at the base of the seminiferous tubules. Sox3 expression was restricted to proliferating germ cells and colocalized with neurogenin 3 (Ngn3), a helix-loop-helix transcription factor implicated in spermatogonial differentiation. The absence of Sox3 decreased Ngn3 and increased expression of Oct4, a marker of undifferentiated spermatogonia. We conclude that Sox3 is expressed in A.sub.s, A.sub.pr and A.sub.al spermatogonia and is required for spermatogenesis through a pathway that involves Ngn3. Author Affiliation: Division of Endocrinology, Metabolism and Molecular Medicine, Feinberg School of Medicine, Northwestern University, Galter Pavilion, Suite 3-150, 251 E. Huron Street, Chicago, IL 60611-2908, USA

Published
2005

33. Model compliance: avoiding the hard-knocks life so the sun will come out tomorrow

Author

Hurley, Lisa

Subjects
United States. Securities and Exchange Commission -- Laws, regulations and rules, United States. Securities and Exchange Commission -- Investigations, Regulatory compliance -- Analysis, Mutual funds -- Laws, regulations and rules, Mutual funds -- Investigations, Investment companies -- Laws, regulations and rules, Investment companies -- Investigations, Government regulation, Company legal issue, Banking, finance and accounting industries, Business, Business, international
Abstract

The October 5, 2004 deadline for complying with Rule 206(4)-7 under the Investment Advisers Act of 1940 has come and gone and it's a whole new world for compliance with [...]

Published
2004

34. IDH3α regulates one-carbon metabolism in glioblastoma

Author

May, Jasmine L., primary, Kouri, Fotini M., additional, Hurley, Lisa A., additional, Liu, Juan, additional, Tommasini-Ghelfi, Serena, additional, Ji, Yanrong, additional, Gao, Peng, additional, Calvert, Andrea E., additional, Lee, Andrew, additional, Chandel, Navdeep S., additional, Davuluri, Ramana V., additional, Horbinski, Craig M., additional, Locasale, Jason W., additional, and Stegh, Alexander H., additional

Published
2019
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35. Effects of fluoxetine on functional outcomes after acute stroke (FOCUS): a pragmatic, double-blind, randomised, controlled trial

Author

Dennis, Martin, primary, Mead, Gillian, additional, Forbes, John, additional, Graham, Catriona, additional, Hackett, Maree, additional, Hankey, Graeme J, additional, House, Allan, additional, Lewis, Stephanie, additional, Lundström, Erik, additional, Sandercock, Peter, additional, Innes, Karen, additional, Williams, Carol, additional, Drever, Jonathan, additional, Mcgrath, Aileen, additional, Deary, Ann, additional, Fraser, Ruth, additional, Anderson, Rosemary, additional, Walker, Pauli, additional, Perry, David, additional, Mcgill, Connor, additional, Buchanan, David, additional, Chun, Yvonne, additional, Dinsmore, Lynn, additional, Maschauer, Emma, additional, Barugh, Amanda, additional, Mikhail, Shadia, additional, Blair, Gordon, additional, Hoeritzauer, Ingrid, additional, Scott, Maggie, additional, Fraser, Greig, additional, Lawrence, Katherine, additional, Shaw, Alison, additional, Williamson, Judith, additional, Burgess, David, additional, Macleod, Malcolm, additional, Morales, Dan, additional, Sullivan, Frank, additional, Brady, Marian, additional, French, Ray, additional, Van Wijck, Frederike, additional, Watkins, Caroline, additional, Proudfoot, Fiona, additional, Skwarski, Joanna, additional, Mcgowan, Diane, additional, Murphy, Rachael, additional, Burgess, Seona, additional, Rutherford, William, additional, Mccormick, Katrina, additional, Buchan, Ruaridh, additional, Macraild, Allan, additional, Paulton, Ruth, additional, Fazal, Adnan, additional, Taylor, Pat, additional, Parakramawansha, Ruwan, additional, Hunter, Neil, additional, Perry, Jack, additional, Bamford, John, additional, Waugh, Dean, additional, Veraque, Emelda, additional, Bedford, Caroline, additional, Kambafwile, Mary, additional, Idrovo, Luis, additional, Makawa, Linetty, additional, Smalley, Paula, additional, Randall, Marc, additional, Thirugnana-Chandran, Tharani, additional, Hassan, Ahamad, additional, Vowden, Richard, additional, Jackson, Joanne, additional, Bhalla, Ajay, additional, Rudd, Anthony, additional, Tam, Chi Kai, additional, Birns, Jonathan, additional, Gibbs, Charlotte, additional, Lee Carbon, Leonie, additional, Cattermole, Elizabeth, additional, Marks, Katherine, additional, Cape, Angela, additional, Hurley, Lisa, additional, Kullane, Sagal, additional, Smyth, Nigel, additional, Eglinton, Charlotte, additional, Wilson, Jennifer, additional, Giallombardo, Elio, additional, Frith, Angela, additional, Reidy, Paul, additional, Pitt, Matthew, additional, Sykes, Lucy, additional, Dellafera, Deborah, additional, Croome, Victoria, additional, Kerwood, Lauriane, additional, Hancevic, Mirea, additional, Narh, Christina, additional, Merritt, Carley, additional, Duffy, John, additional, Cooke, Duncan, additional, Willson, Juliet, additional, Ali, Ali, additional, Naqvi, Aaizza, additional, Kamara, Christine, additional, Bowler, Helen, additional, Bell, Simon, additional, Jackson, Tracy, additional, Harkness, Kirsty, additional, Stocks, Kathy, additional, Duty, Suzanna, additional, Doyle, Clare, additional, Dunn, Geoffrey, additional, Endean, Keith, additional, Claydon, Fiona, additional, Richards, Emma, additional, Howe, Jo, additional, Lindert, Ralf, additional, Majid, Arshad, additional, Dakin, Katy, additional, Maatouk, Ahmad, additional, Barron, Luke, additional, Meegada, Madana, additional, Rana, Pratap, additional, Nair, Anand, additional, Brighouse-Johnson, Christine, additional, Greig, Jill, additional, Kyu, Myint, additional, Prasad, Sanjeev, additional, Robinson, Matthew, additional, Alam, Irfan, additional, Mclean, Belinda, additional, Greenhalgh, Lindsay, additional, Ahmed, Zenab, additional, Roffe, Christine, additional, Brammer, Susan, additional, Beardmore, Carole, additional, Finney, Kay, additional, Barry, Adrian, additional, Hollinshead, Paul, additional, Grocott, Jeanette, additional, Maguire, Holly, additional, Natarajan, Indira, additional, Chembala, Jayan, additional, Sanyal, Ranjan, additional, Lijko, Sue, additional, Abano, Nenette, additional, Remegoso, Alda, additional, Ferdinand, Phillip, additional, Stevens, Stephanie, additional, Varquez, Resti, additional, Causley, Chelsea, additional, Butler, Adrian, additional, Whitmore, Philip, additional, Stephen, Caroline, additional, Carpio, Racquel, additional, Hiden, Joanne, additional, Muddegowda, Girish, additional, Denic, Hayley, additional, Sword, Jane, additional, Curwen, Ross, additional, James, Martin, additional, Mudd, Paul, additional, Hall, Fiona, additional, Cageao, Julie, additional, Keenan, Samantha, additional, Roughan, Caroline, additional, Kingwell, Hayley, additional, Hemsley, Anthony, additional, Lohan, Christoph, additional, Davenport, Sue, additional, Bowring, Angela, additional, Chapter, Tamika, additional, Hough, Max, additional, Strain, David, additional, Gupwell, Karin, additional, Miller, Keniesha, additional, Goff, Anita, additional, Cusack, Ellie, additional, Todd, Shirley, additional, Partridge, Rebecca, additional, Jennings, Georgiana, additional, Thorpe, Kevin, additional, Stephenson, Jacquelyn, additional, Littlewood, Kelly, additional, Barber, Mark, additional, Brodie, Fiona, additional, Marshall, Steven, additional, Esson, Derek, additional, Coburn, Irene, additional, Mcinnes, Caroline, additional, Ross, Fiona, additional, Bowie, Emma, additional, Barcroft, Heather, additional, Withers, Victoria, additional, Miller, Laura, additional, Willcoxson, Paul, additional, Donninson, Michelle, additional, Evans, Richard, additional, Daniel, Di, additional, Coyle, John, additional, Keeling, Michael, additional, Wanklyn, Peter, additional, Elliott, Mark, additional, Wightman, John, additional, Iveson, Elizabeth, additional, Dyer, Natasha, additional, Porteous, Anne-Marie, additional, Haritakis, Monica, additional, Ward, Mandy, additional, Doughty, Lucy, additional, Carr, Lisa, additional, O Neill, Mark, additional, Anazodo, Cosmas, additional, Wood, Paul, additional, Cottrell, Poppy, additional, Donne, Cheryl, additional, Rodriguez, Romina, additional, Mir, Ruhail, additional, Westmoreland, Jax, additional, Bell, Judith, additional, Emms, Christopher, additional, Wright, Lorraine, additional, Clark Brown, Pearl, additional, Bamford, Elizabeth, additional, Stanners, Andrew, additional, Carpenter, Mike, additional, Datta, Prabal, additional, Davey, Richard, additional, Needle, Ann, additional, Eastwood, Marjorie Jane, additional, Razik, Fathima Zeena, additional, Ghouri, Imran, additional, Bateman, Gavin, additional, Archer, Judy, additional, Balasubramanian, Venkatesh, additional, Bowers, Richard, additional, Ball, Julie, additional, Benton, Louise, additional, Jackson, Linda, additional, Ellam, Julie, additional, Norton, Kate, additional, Guyler, Paul, additional, Dowling, Terry, additional, Tysoe, Sharon, additional, Harman, Paula, additional, Kundu, Ashish, additional, Omodunbi, Ololade, additional, Loganathan, Thayalini, additional, Chandler, Stuart, additional, Noor, Shanas, additional, Siddiqui, Anwer, additional, Siddiqui, Amber, additional, Kunhunny, Swapna, additional, Sinha, Devesh, additional, Sheppard, Martin, additional, Rashmi, Sindhu, additional, France, Elena, additional, Orath Prabakaran, Rajalakshmi, additional, Wilson, Laura, additional, Ropun, Amiirah, additional, Kelavkar, Shyam, additional, Ng, Kheng Xiong, additional, Kamuriwo, Lucy, additional, Shah, Sweni, additional, Mangion, David, additional, Constantin, Camen, additional, De Michele Hock, Luigi, additional, Hardwick, Anne, additional, Borley, Jayne, additional, Markova, Skarlet, additional, Netherton, Kimberley, additional, Lawrence, Tara, additional, Fletcher, Jo, additional, Spencer, Rebecca, additional, Palmer, Helen, additional, Cullen, Claire, additional, Hamill, Dolores, additional, Durairaj, Ramesh, additional, Mellor, Zoe, additional, Fluskey, Tanya, additional, Wood, Diane, additional, Keeling, Alison, additional, Hankin, Victoria, additional, Peters, Jennifer, additional, Shackcloth, Daniela, additional, Hlaing, Thant, additional, Tangney, Rebecca, additional, Ewing, Jordan, additional, Harrison, Melanie, additional, Stevenson, Sarah, additional, Sutton, Victoria, additional, Soliman, Mohamed, additional, Hindle, Julia, additional, Watson, Elizabeth, additional, Hewitt, Claire, additional, Butler, Susie, additional, Wahishi, Ibrahim, additional, Arif, Sarwat, additional, Fields, Amy, additional, Sharma, Jagdish, additional, Brown, Rose, additional, Taylor, Caroline, additional, Bell, Sarah, additional, Leach, Simon, additional, Patterson, Chris, additional, Khan, Sophia, additional, Wilson, Helen, additional, Price, Joanne, additional, Ramadan, Hawraman, additional, Maguire, Stuart, additional, Bellfield, Ruth, additional, Hooley, Michaela, additional, Hamid, Umair, additional, Gaba, Waqar, additional, Ghulam, Robina, additional, Masters, Leslie, additional, Quinn, Outi, additional, Sekaran, Lakshmanan, additional, Tate, Margaret, additional, Mohammed, Niaz, additional, Bharaj, Kiranjit, additional, Justin, Frances, additional, Pattni, Rajan, additional, Alwis, Lanka, additional, Sethuraman, Sakthivel, additional, Robinson, Rianne, additional, Eldridge, Lianne, additional, Mintias, Susan, additional, Chauhan, Meena, additional, Tam, Chi-Kai, additional, Palmones, Jeremias, additional, Holmes, Clare, additional, Guthrie, Lucy Belle, additional, Osborn, Mairead, additional, Ball, Lindsay, additional, Caine, Sarah, additional, Steele, Amy, additional, Murphy, Peter, additional, Devitt, Nikki, additional, Leonard, Jayne, additional, Patel, Ronak, additional, Penwarden, Ian, additional, Dodd, Emily, additional, Holloway, Amy, additional, Baker, Pauline, additional, Clarke, Samantha, additional, Williams, Sandra, additional, Dow, Lindsey, additional, Wynn-Williams, Roland, additional, Kennedy, James, additional, Teal, Rachel, additional, Schulz, Ursula, additional, Ford, Gary, additional, Mathieson, Philip, additional, Reckless, Ian, additional, Deveciana, Ana, additional, Mccann, Paige, additional, Cluckie, Gillian, additional, Howell, Geoffrey, additional, Ayer, Jonathan, additional, Moynihan, Barry, additional, Ghatala, Rita, additional, Clarke, Brian, additional, Cloud, Geoffrey, additional, Patel, Bhavini, additional, Khan, Usman, additional, Al-Samarrai, Nia, additional, Trippier, Sarah, additional, Chopra, Neha, additional, Adedoyin, Temi, additional, Watson, Fran, additional, Jones, Val, additional, Zhang, Liqun, additional, Choy, Lillian, additional, Williams, Rebecca, additional, Clarke, Natasha, additional, Blight, Adrian, additional, Kennedy, Kate, additional, Dainty, Alice, additional, Selvarajah, Johann, additional, Kalladka, Dheeraj, additional, Cheripelli, Bharath, additional, Smith, Wilma, additional, Moreton, Fiona, additional, Welch, Angela, additional, Huang, Xuya, additional, Douglas, Elizabeth, additional, Lush, Audrey, additional, Day, Nicola, additional, El Tawil, Salwa, additional, Montgomery, Karen, additional, Hamilton, Helen, additional, Ritchie, Doreen, additional, Ramachandra, Sankaranarayanan, additional, Mcleish, Kirsty, additional, Thavanesan, Kamy, additional, Loganathan, Sathyabama, additional, Roberts, Josh, additional, Cox, Chantel, additional, Orr, Sarah, additional, Hogan, Alison, additional, Tiwari, Divya, additional, Hann, Gail, additional, Longland, Barbara, additional, David, Owen, additional, Bell, Jo, additional, Ovington, Catherine, additional, Rogers, Emily, additional, Bower, Rachel, additional, Keltos, Marketa, additional, Cohen, David, additional, Devine, Joseph, additional, Alwis, Lankantha, additional, Southworth, Lucy, additional, Burgess, Laura, additional, Lang, Matilda, additional, Badiani, Bhavna, additional, Guo, Fenglin, additional, Oshodi, Anne, additional, Owoyele, Emmanuelle, additional, Epie, Norah, additional, David, Anette, additional, Mpelembue, Mushiya, additional, Bathula, Rajaram, additional, Abdul-Saheb, Mudhar, additional, Chamberlain, Angela, additional, Sudkeo, Varthi, additional, Rashed, Khalid, additional, Williams-Yesson, Barbara, additional, Board, Joanne, additional, De Bruijn, Sarah, additional, Buckley, Clare, additional, Board, Sarah, additional, Allison, Joanna, additional, Keeling, Elizabeth, additional, Duckett, Tracey, additional, Donaldson, Dave, additional, Vickers, Carinna, additional, Barron, Claire, additional, Balian, Linda, additional, Wilson, Jodhi, additional, Edwards, Adam, additional, England, Timothy, additional, Hedstrom, Amanda, additional, Bedford, Elizabeth, additional, Harper, Margaret, additional, Melikyan, Elina, additional, Abbott, Wendy, additional, Subramanian, Kashmira, additional, Goldsworthy, Marie, additional, Srinivasan, Meena, additional, Yeomans, Angela, additional, Donaldson, Denise, additional, Hurford, Frances, additional, Chapman, Riquella, additional, Shahzad, Sana, additional, Motherwell, Nicki, additional, Tonks, Louise, additional, Young, Rachel, additional, Ghani, Usman, additional, Mukherjee, Indranil, additional, Dutta, Dipankar, additional, Obaid, Mudhar, additional, Brown, Pauline, additional, Davis, Fiona, additional, Ward, Deborah, additional, Turfrey, Jennifer, additional, Cartwright, Bethan, additional, Topia, Bilal, additional, Spurway, Judith, additional, Collins, Kayleigh, additional, Bakawala, Rehana, additional, Hughes, Chloe, additional, Oconnell, Susan, additional, Hill, Linda, additional, Chatterjee, Kausik, additional, Webster, Tim, additional, Haider, Syed, additional, Rushworth, Pamela, additional, Macleod, Fiona, additional, Nallasivan, Arumugam, additional, Perkins, Charlotte, additional, Burns, Edel, additional, Leason, Sandra, additional, Carter, Tom, additional, Seagrave, Samantha, additional, Sami, Eman, additional, Armstrong, Lisa, additional, Naqvi, Syed Naseem, additional, Hassan, Muhammad, additional, Parkinson, Sharron, additional, Mawer, Samantha, additional, Darnbrook, Gillian, additional, Booth, Carl, additional, Hairsine, Brigid, additional, Smith, Matthew, additional, Williamson, Sue, additional, Farquhar, Fiona, additional, Esisi, Bernard, additional, Cassidy, Tim, additional, Mankin, Gavin, additional, Mcclelland, Beverley, additional, Bokhari, Maria, additional, Sproates, David, additional, Epstein, Elliot, additional, Hurdowar, Steve, additional, Blackburn, Ruth, additional, Sukhdeep, Nazran, additional, Razak, Saika, additional, Osman, Khalid, additional, Hashmi, Amina, additional, Upton, Natasha, additional, Harrington, Frances, additional, Courtauld, Gillian, additional, Schofield, Christine, additional, Lucas, Linda, additional, Adie, Katja, additional, Bond, Kirsty, additional, Mate, Abhijit, additional, Skewes, Jo, additional, James, Ali, additional, Brodie, Carolyn, additional, Johnson, Matthew, additional, Allsop, Linda, additional, Driver, Emma, additional, Harris, Karina, additional, Drake, Mark, additional, Ellis, Sam, additional, Maund, Bev, additional, Thomas, Emma, additional, Moore, Kimberley, additional, Burn, Matthew, additional, Hamilton, Adam, additional, Mahalingam, Shageetha, additional, Misra, Amulya, additional, Reid, Farrah, additional, Benford, Adrienne, additional, Hilton, Derek, additional, Hazell, Lorraine, additional, Ofori, Keziah, additional, Thomas, Anne Louise, additional, Mathew, Moncy, additional, Dayal, Sonia, additional, Burn, Iona, additional, Fotherby, Kenneth, additional, Jennings-Preece, Karla, additional, Willberry, Angela, additional, Morgan, Debbie, additional, Butler, Donna, additional, Sahota, Gurminder, additional, Kauldhar, Kelly, additional, Ahmad, Nasar, additional, Stevens, Angela, additional, Das, Saugata, additional, Bruce, David, additional, Pai, Yogish, additional, Nyo, Khin, additional, Stephenson, Lynsey, additional, Nendick, Richard, additional, Rogers, Gill, additional, Dhakal, Mahesh, additional, Dima, Sofia, additional, Brown, Ellen, additional, Clayton, Susan, additional, Gamble, Penny, additional, Naeem, Muhammad, additional, Hayman, Rachel, additional, Burnip, Rachel, additional, Earnshaw, Philip, additional, Hargroves, David, additional, Ransom, Barbara, additional, Rudenko, Hannah, additional, Balogun, Ibrahim, additional, Griffiths, Kirsty, additional, Mears, Kim, additional, Webb, Tom, additional, Cowie, Linda, additional, Hammond, Tessa, additional, Thomson, Audrey, additional, Ceccarelli, Daniela, additional, Chattha, Navraj, additional, Beranova, Eva, additional, Verrion, Anna, additional, Gillian, Andrew, additional, Schumacher, Natasha, additional, Bahk, Anna, additional, Walker, Susannah, additional, Cvoro, Vera, additional, Chapman, Nicola, additional, Pound, Susan, additional, Cain, Rebecca, additional, Mcauley, Sean, additional, Couser, Mandy, additional, Simpson, Maria, additional, Tachtatzis, Athan, additional, Ullah, Khalil, additional, Sims, Don, additional, Jones, Rachael, additional, Smith, Jonathan, additional, Tongue, Rebecca, additional, Willmot, Mark, additional, Sutton, Claire, additional, Littleton, Edward, additional, Khaira, Jattinder, additional, Maiden, Susan, additional, Cunningham, James, additional, Green, Carole, additional, Chin, Yin-May, additional, Bates, Michelle, additional, Ahlquist, Katherine, additional, Kane, Ingrid, additional, Breeds, Joanna, additional, Sargent, Tenesa, additional, Latter, Laura, additional, Pitt Ford, Alexandra, additional, Gainsborough, Nicola, additional, Levett, Tom, additional, Thompson, Philip, additional, Barbon, Emma, additional, Dunne, Angela, additional, Hervey, Simon, additional, Ragab, Suzanne, additional, Sandell, Tracy, additional, Dickson, Christine, additional, Dube, Judith, additional, Power, Sharon, additional, Evans, Nick, additional, Wadams, Beverley, additional, Elitova, Savina, additional, Aubrey, Beth, additional, Garcia, Tatiana, additional, Mcilmoyle, James, additional, Jeffs, Carol, additional, Dickinson, Christina, additional, Ahmed, Anis, additional, Kumar, Sanjeev, additional, Frudd, Julie, additional, Armer, Charlotte, additional, Potter, Andrew, additional, Donaldson, Stacey, additional, Howard, Joanne, additional, Jones, Kirsty, additional, Dhar, Saikat, additional, Collas, David, additional, Sundayi, Saul, additional, Denham, Lynn, additional, Oza, Deepali, additional, Walker, Elaine, additional, Bhandari, Mohit, additional, Ispoglou, Sissy, additional, Evans, Rachel, additional, Sharobeem, Kamel, additional, Walton, Elaine, additional, Shanu, Steven, additional, Hayes, Anne, additional, Howard-Brown, Jennifer, additional, Billingham, Steven, additional, Weir, Nic, additional, Pressly, Vanessa, additional, Wood, Emma, additional, Howard, Gabriella, additional, Burton, Holly, additional, Crawford, Pam, additional, Egerton, Shuna, additional, Evans, Sue, additional, Hakkak, Jasmine, additional, Andrews, Janet, additional, Lampard, Rebecca, additional, Allen, Christopher, additional, Walters, Ashleigh, additional, Said, Rasha, additional, Marigold, James Richard, additional, Tsang, Sau-Mon, additional, Creeden, Robyn, additional, Cox, Chloe, additional, Smith, Simon, additional, Gartrell, Imogen, additional, Smith, Fiona, additional, Jenkins, Colin, additional, Pryor, Joanna, additional, Hedges, Andrew, additional, Price, Fiona, additional, Moseley, Linda, additional, Mercer, Lily, additional, Hughes, Claire, additional, Azim, Abul, additional, White, Julie, additional, Krasinska-Chavez, Milena, additional, Chaplin, Shaun, additional, Curtis, James, additional, Singh, Deepwant, additional, Imam, Javed, additional, Nicolson, Anne, additional, Alam, Sajid, additional, Whitworth, Simon, additional, Wood, Lisa, additional, Warburton, Elizabeth, additional, Kelly, Siobhan, additional, Mcgee, Joanne, additional, Markus, Hugh, additional, Chandrasena, Denish, additional, Hayden, Derek, additional, Sesay, Juliana, additional, Hayhoe, Helen, additional, Bolton, Mark, additional, Macdonald, Jane, additional, Mitchell, Jenny, additional, Farron, Charlotte, additional, Amis, Elaine, additional, Day, Diana, additional, Culbert, Ainsley, additional, Espanol, Ailene, additional, Hannon, Niamh, additional, Handley, Dominic, additional, Finlay, Sarah, additional, Crisp, Sarah, additional, Whitehead, Lynne, additional, Francis, Jobbin, additional, Oconnell, Janice, additional, Osborne, Emily, additional, Beard, Rod, additional, Krishnamurthy, Ramesh, additional, Mokoena, Langanani, additional, Sattar, Naweed, additional, Myint, Min, additional, Edwards, Michelle, additional, Smith, Andrew, additional, Corrigan, Paul, additional, Byrne, Anthony, additional, Blackburn, Joanne, additional, Mcghee, Caroline, additional, Smart, Amanda, additional, Donaldson, Fiona, additional, Copeland, Claire, additional, Wilson, Jill, additional, Scott, Rhona, additional, Fitzsimmons, Paul, additional, Lopez, Paula, additional, Wilkinson, Mark, additional, Manoj, Aravindakshan, additional, Cox, Penelope, additional, Trainor, Leona, additional, Fletcher, Glyn, additional, Denny, Lisa, additional, Kavanagh, Karen, additional, Allsop, Hannah, additional, Emsley, Hedley, additional, Sultan, Sulaiman, additional, Mcloughlin, Alison, additional, Walmsley, Benjamin, additional, Hough, Louise, additional, Ahmed, Shakeel, additional, Doyle, Donna, additional, Gregary, Bindu, additional, Raj, Sonia, additional, Nagaratnam, Kirubananthan, additional, Mannava, Neelima, additional, Haque, Nyla, additional, Shields, Norma, additional, Preston, Kate, additional, Mason, Geraldine, additional, Short, Kirsty, additional, Lumsdale, Gemma, additional, Uitenbosch, Giulia, additional, Sukys, Ugnius, additional, Valentine, Stacey, additional, Jarrett, David, additional, Dodsworth, Kerry, additional, Wands, Mary, additional, Khan, Nisa, additional, Tandy, Jane, additional, Watkinson, Catrin, additional, Golding, Wendy, additional, Butler, Rebecca, additional, Williams, Max, additional, Davies, Yasmin, additional, Yip, Keith, additional, James, Claire, additional, Suttling, Anne, additional, Maney, Aditya, additional, Gamble, Giles Edward, additional, Hague, Adam, additional, Charles, Bethan, additional, Blane, Sujata, additional, Duran, Beatriz, additional, Lambert, Caroline, additional, Stagg, Katherine, additional, Whiting, Robert, additional, Homan, Jane E, additional, Brown, Sarah, additional, Hussain, Malik, additional, Harvey, Miriam, additional, Graham, Libby, additional, Foote, Leanne, additional, Lane, Catherine, additional, Kemp, Liz (Joan), additional, Rowe, Joy, additional, Durman, Helen, additional, Foot, Jayne, additional, Brotherton, Lucy, additional, Hunt, Nicholas, additional, Pawley, Corinne, additional, Whitcher, Alison, additional, Sutton, Patrick, additional, Mcdonald, Susan, additional, Pak, Denys, additional, Wiltshire, Alison, additional, Jagger, Jennifer, additional, Metcalf, Anthony K, additional, Healey, Gail Louise, additional, Balami, Joyce, additional, Self, Clare Marie, additional, Crofts, Melissa, additional, Chakrabarti, Annie, additional, Hmu, Chit, additional, Ravenhill, Garth, additional, Grimmer, Charmaine, additional, Soe, Thandar, additional, Keshet-Price, Jocelyn, additional, Langley, Margaret, additional, Potter, Ian, additional, Tam, Pui-Lin, additional, Macleod, Mary Joan, additional, Cooper, Patricia, additional, Christie, Michael, additional, Irvine, Janice, additional, Annison, Faye, additional, Christie, David, additional, Meneses, Celia, additional, Johnson, Amber, additional, Joyson, Anu, additional, Nelson, Sandra, additional, Taylor, Vicky, additional, Reid, John, additional, Clarke, Rebecca, additional, Furnace, Jacqueline, additional, Gow, Heather, additional, Abousleiman, Youssif, additional, Beadling, Tania, additional, Collins, Sally, additional, Jones, Stuart, additional, Purcell, Jessica, additional, Bloom, Samantha, additional, Goshawk, Shelly, additional, Landicho, Marcial, additional, Sangaralingham, Sivatharshini, additional, Begum, Yasmin, additional, Mutton, Sherree, additional, Munuswamy Vaiyapuri, Elangovan, additional, Allen, Jane, additional, Lowe, Jemma, additional, Hughes, Martin, additional, Wiggam, Ivan, additional, Cuddy, Sarah, additional, Tauro, Suzanne, additional, Wells, Brian, additional, Mohd Nor, Azlisham, additional, Persad, Nicola, additional, Kalita, Maggie, additional, Weatherby, Stuart, additional, Brown, Claire, additional, Pace, Adrian, additional, Lashley, Daniel, additional, Marner, Mike, additional, Weinling, Marie, additional, Wilmshurst, Natasha, additional, Waugh, Darren, additional, Mucha, Anna, additional, Shah, Alex, additional, Baker, John, additional, Westcott, Jacqueline, additional, Cowan, Richard, additional, Vasileiadis, Evangelos, additional, Mumani, Samira, additional, Parry, Anthea, additional, Mason, Cathy, additional, Holden, Melinda, additional, Petrides, Katerina, additional, Nishiyama, Tomoko, additional, Mehta, Hina, additional, Krishnan, Manju, additional, Lynne, Dacey, additional, Thomas, Lisa, additional, Lynda, Connor, additional, Hughes, Catherine, additional, Clements, Clare, additional, Williams, Rhys, additional, Anjum, Tal, additional, Sharon, Storton, additional, Tucker, Susan, additional, Jones, Paul, additional, Colwill, Deanne, additional, Thompson Jones, Helen, additional, Chadha, Dinesh, additional, Fairweather, Mark, additional, Walstow, Deborah, additional, Fong, Rosanna, additional, Johnston, Stuart, additional, Almadenboyle, Christine, additional, Ross, Sarah, additional, Carson, Shona, additional, Nair, Priya, additional, Tenbruck, Emily, additional, Stirling, Mairi, additional, Pusalkar, Aparna, additional, Beadle, Hannah, additional, Chan, Kelly, additional, Dangri, Puneet, additional, Asokanathan, Asaipillai, additional, Rana, Anita, additional, Gohil, Sunita, additional, Massyn, Mark, additional, Aruldoss, Prabhu, additional, Cook, Angela, additional, Crabtree, Karen, additional, Dabbagh, Sura, additional, Black, Toby, additional, Clarke, Caroline, additional, Mead, Denise, additional, Fennelly, Ruth, additional, Anthony, Alpha, additional, Nardone, Linda, additional, Dimartino, Victoria, additional, Tribbeck, Michele, additional, Broughton, David, additional, Tryambake, Dinesh, additional, Dixon, Lynn, additional, Skotnicka, Agnieszka, additional, Thompson, Jane, additional, Whitehouse, Sarah, additional, Sigsworth, Andrew, additional, Wong, Jason, additional, Annamalai, Arunkumar, additional, Pagan, Julie, additional, Affley, Brendan, additional, Sunderland, Caroline, additional, Goldenberg, Lynda, additional, Khan, Atif, additional, Wilkinson, Peter, additional, Nari, Raad, additional, Abbott, Lucy, additional, Young, Emma, additional, Shakhon, Amritpal, additional, Lock, Sally, additional, Stewart, Jack, additional, Pereira, Rita, additional, Dsouza, Margaret, additional, Dunn, Sally, additional, Mckenna, Anne-Marie, additional, Cron, Nina, additional, Kidd, Michelle, additional, Hull, Grace, additional, Bunworth, Kerry, additional, Drummond, Graham, additional, Mahawish, Karim, additional, Hayes, Nicola, additional, Connell, Lynne, additional, Simpson, Jennifer, additional, Penney, Helen, additional, Punekar, Shuja, additional, Nevinson, Joanne, additional, Wareing, William, additional, Ward, Jacqueline, additional, Greenwood, Richard, additional, Austin, Duncan, additional, Banaras, Azra, additional, Hogan, Carolin, additional, Corbett, Thomas, additional, Oji, Nnebuife, additional, Elliott, Emma, additional, Brezitski, Maria, additional, Passeron, Nathalie, additional, Howaniec, Laura, additional, Watchurst, Caroline, additional, Patel, Krishna, additional, Erande, Renuka, additional, Shah, Rahi, additional, Sengupta, Nabarun, additional, Metiu, Maria, additional, Gonzalez, Celia, additional, Funnell, Sarah, additional, Margalef, Jordi, additional, Peters, Gillian, additional, Chadbourn, Indra, additional, Sivakumar, Ramachandran, additional, Saksena, Rajesh, additional, Ketley-O'donel, Jane, additional, Needle, Richard, additional, Chinery, Elaine, additional, Wright, Alison, additional, Cook, Sue, additional, Ngeh, Joseph, additional, Proeschel, Harald, additional, Cook, Paige, additional, Ashcroft, Pauline, additional, Sharpe, Simon, additional, Jones, Stephanie, additional, Jenkinson, Damian, additional, Kelly, Deborah, additional, Bray, Holly, additional, Gunathilagan, Gunaratnam, additional, Jones, Sally, additional, Tilbey, Sorrell, additional, Abubakar, Saidu, additional, Vassallo, Joseph, additional, Leonard, Dee, additional, Orrell, Lucy, additional, Hasan, Aziz, additional, Khan, Asif, additional, Qamar, Sulmaaz, additional, Graham, Susan, additional, Hewitt, Emma, additional, Awolesi, Jennifer, additional, Haque, Muhammad, additional, Kent, Alissa, additional, Bradshaw, Elizabeth, additional, Cooper, Martin, additional, Wynter, Inez, additional, Rajapakse, Anoja, additional, Janbieh, Joumana, additional, Nasar, Abu M, additional, Wade, Lynne, additional, Otter, Linda, additional, Haigh, Steve, additional, Burgoyne, Jamie-Rae, additional, Boulton, Rebecca, additional, Boulton, Andrew, additional, Rayessa, Rayessa, additional, Clarkson, Emma, additional, Rhian, Horne, additional, Fleming, Amy, additional, Mitchelson, Kim, additional, Lowthorpe, Vicki, additional, Abdul-Hamid, Ahmed, additional, Jones, Phil, additional, Duggan, Claire, additional, Hynes, Abigail, additional, Nurse, Emma, additional, Raza, Syed Abid, additional, Jones, Sarah, additional, Pallikona, Udaya, additional, Edwards, Bleddyn, additional, Morgan, Geraint, additional, Dennett, Kirsty, additional, Tench, Helen, additional, Loosley, Ronda, additional, Trugeon-Smith, Toby, additional, Jones, Rhian, additional, Williams, Richard, additional, Robson, Donna, additional, Mavinamane, Sunanda, additional, Meenakshisundaram, Sanjeevi, additional, Ranga, Lalitha, additional, Dealing, Sharon, additional, Hill, Andrew, additional, Hargreaves, Margaret, additional, Smith, Tom, additional, Bate, Julie, additional, Harrison, Linda, additional, Kirthivasan, Ramanathan, additional, Cannon, Emma, additional, Topliffe, Joanne, additional, Keskeys, Rebecca, additional, Williams, Sarah, additional, Mcneela, Fiona, additional, Cairns, Frances, additional, James, Thomas, additional, Lyle, Amanda, additional, Shah, Sheela, additional, Zachariah, George, additional, Fergey, Lauren, additional, Smolen, Susan, additional, Cooper, Lucy, additional, Bohannan, Elizabeth, additional, Omer, Siddiq, additional, Amlani, Sageet, additional, Hunter, Nadia, additional, Hawkes-Blackburn, Melissa, additional, Gulli, Giosue, additional, Peacocke, Alice, additional, Amero, Justine, additional, Burova, Maria, additional, Speirs, Ottilia, additional, Levy, Steph, additional, Francis, Lynda, additional, Holland, Susan, additional, Brotheridge, Sean, additional, Lyon, Helen, additional, Hare, Christine, additional, Jackson, Samantha, additional, Stephenson, Lorraine, additional, Al Hussayni, Samer, additional, Featherstone, James, additional, Bwalya, Agness, additional, Singh, Arun, additional, Goorah, M N, additional, Walford, Jamie, additional, Bell, Angela, additional, Kelly, Christine, additional, Rusk, Darren, additional, Sutton, Deborah, additional, Patel, Farzana, additional, Duberley, Stephen, additional, Hayes, Kathryn, additional, Hunt, Lorraine, additional, El Nour, Ahmed, additional, Honour, Sacha, additional, Box, Chloe, additional, Dyer, Simon, additional, Brown, Lynne, additional, Elliott, Kerry, additional, Temlett, Emma, additional, Paterson, John, additional, Furness, Rosie, additional, Young, Shelli, additional, Orugun, Enoch, additional, Brewer, Chris, additional, Thornthwaite, Sarah, additional, Crowther, Hannah, additional, Glover, Rachel, additional, Sein, Moe, additional, Haque, Kashif, additional, Gibson, Elspeth, additional, Wong, Sam, additional, Rotchell, Karen, additional, Burton, Karen, additional, Brookes, Lisa, additional, Bailey, Linda, additional, Lindley, Chris, additional, Murray, Abbi, additional, Waltho, Karen, additional, Holland, Maureen, additional, Kumar, Pradeep, additional, Harlekar, Purnima, additional, Booth, Laura, additional, Culmsee, Charlotte, additional, Drew, Jade, additional, Khan, Mohammad, additional, Mackenzie, Nicola, additional, Thomas, Carmel, additional, Ritchie, Jane, additional, Barker, James, additional, Haley, Michael, additional, Cotterill, Donna, additional, Lane, Lynne, additional, Little, Christine, additional, Simmons, Dawn, additional, Saunders, Glenn, additional, Dymond, Harvey, additional, Kidd, Sarah, additional, Warinton, Rachel, additional, Neves-Silva, Yara, additional, Nevajda, Branimir, additional, Villaruel, Michael, additional, Umasankar, Udayaraj, additional, Patel, Seema, additional, Man, Anna, additional, Christmas, Natasha, additional, Rangasamy, Ravi, additional, Ladner, Richard, additional, Butt, Georgina, additional, Alvares, Wilson, additional, Gadi, Narasimha, additional, Power, Michael, additional, Wroath, Belinda, additional, Dynan, Kevin, additional, Wilson, David, additional, Crothers, Sarah, additional, Leonard, Catherine, additional, Hagan, Samantha, additional, Douris, Geraldine, additional, Vahidassr, Djamil, additional, Thompson, Alastair, additional, Gallen, Brian, additional, Mckenna, Shirley, additional, Edwards, Collette, additional, Mcgoldrick, Clare, additional, Bhattad, Murdi, additional, Kawafi, Khalil, additional, Morse, Deborah, additional, Jacob, Patricia, additional, Turner, Lisa, additional, Saravanan, Narayanamoorti, additional, Johnson, Linda, additional, Humphrey, Sadie, additional, Namushi, Robert, additional, Patel, Ramesh, additional, Mclaughlin, Jemma, additional, Omahony, Paul, additional, Osikominu, Esther, additional, Orefo, Chukwuka, additional, Mcdonald, Chisha, additional, Makanju, Esther, additional, Khan, Tabindah, additional, Appiatse, Grace, additional, Stone, Helena, additional, Augustin, Martia, additional, Wardale, Alicia, additional, Salehin, Maqsud, additional, Bailey, Duncan, additional, Garcia-Alen, Luciano, additional, Kalathil, Latheef, additional, Tinsley, Sarah, additional, Jones, Taya, additional, Amor, Kelly, additional, Ritchings, Andrew, additional, Margerum, Emma, additional, Horton, Jane, additional, Miller, Richard, additional, Gautam, Nireekshana, additional, Meir, Julie, additional, Jones, Amaryl, additional, Putteril, Janet, additional, Lepore, Mirella, additional, Gallifent, Rachel, additional, Arundell, Laura-Louise, additional, Mcredmond, Catherine, additional, Goulding, Alicia, additional, Nadarajan, Vivek, additional, Laurence, Julia, additional, Fung Lo, Su, additional, Melander, Sabina, additional, Nicholas, Paul, additional, Woodford, Elizabeth, additional, Mckenzie, Gillian, additional, Le, Vietland, additional, Crause, Jacolene, additional, Luder, Robert, additional, Bhargava, Maneesh, additional, Bhome, Girish, additional, Johnson, Venetia V, additional, Chesser, Dara, additional, Bridger, Hayley, additional, Murali, Elodie, additional, Scott, Jon, additional, Morrison, Susan, additional, Burns, Amy, additional, Graham, Julie, additional, Duffy, Madeline, additional, Ali, Khalid, additional, Pitcher, Emma, additional, Gaylard, Jane, additional, Newman, Julie, additional, Punnoose, Sunil, additional, Besley, Sarah, additional, Purohit, Kirtan, additional, Rees, Amy, additional, Davy, Mark, additional, Chohan, Osman, additional, Khan, Muhammad Fozan, additional, Walker, Rachel, additional, Murray, Vicky, additional, Bent, Charlotte, additional, Oakley, Susan, additional, Peixoto, Cassilda, additional, Jones, Suzanne, additional, Livingstone, Gaybrielle, additional, Butler, Fiona, additional, Bradfield, Sally, additional, Gordon, Laura, additional, Schmit, Jenneke, additional, Wijewardane, Anika, additional, Edmunds, Tineke, additional, Wills, Rebecca, additional, Medcalf, Catherine, additional, Argandona, Lucia, additional, Cuenoud, Larissa, additional, Hassan, Hanna, additional, Erumere, Esther, additional, Ocallaghan, Aidan, additional, Gompertz, Patrick, additional, Redjep, Ozlem, additional, Auld, Grace, additional, Song, Anna, additional, Tarkas, Tillana, additional, Kabash, Hashim, additional, and Hungwe, Rumbi, additional

Published
2019
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36. Adjunctive rifampicin for Staphylococcus aureus bacteraemia (ARREST): a multicentre, randomised, double-blind, placebo-controlled trial

Author

Thwaites, Guy E, primary, Scarborough, Matthew, additional, Szubert, Alexander, additional, Nsutebu, Emmanuel, additional, Tilley, Robert, additional, Greig, Julia, additional, Wyllie, Sarah A, additional, Wilson, Peter, additional, Auckland, Cressida, additional, Cairns, Janet, additional, Ward, Denise, additional, Lal, Pankaj, additional, Guleri, Achyut, additional, Jenkins, Neil, additional, Sutton, Julian, additional, Wiselka, Martin, additional, Armando, Gonzalez-Ruiz, additional, Graham, Clive, additional, Chadwick, Paul R, additional, Barlow, Gavin, additional, Gordon, N Claire, additional, Young, Bernadette, additional, Meisner, Sarah, additional, McWhinney, Paul, additional, Price, David A, additional, Harvey, David, additional, Nayar, Deepa, additional, Jeyaratnam, Dakshika, additional, Planche, Tim, additional, Minton, Jane, additional, Hudson, Fleur, additional, Hopkins, Susan, additional, Williams, John, additional, Török, M Estee, additional, Llewelyn, Martin J, additional, Edgeworth, Jonathan D, additional, Walker, A Sarah, additional, Kamfose, Musa, additional, de Veciana, Ana, additional, Gordon, Nicola Claire, additional, Peto, Leon, additional, Pill, Gemma, additional, Clarke, Tiphanie, additional, Watson, Laura, additional, Griffiths, Dai, additional, Vaughn, Ali, additional, Anson, Luke, additional, Liu, Elian, additional, Perera, Sanuki, additional, Rylance-Knight, Lydia, additional, Cantell, Carmen, additional, Moroney, Ruth, additional, Thwaites, Guy, additional, Bisnauthsing, Karen, additional, Querol-Rubiera, Antonio, additional, Gibbs, Charlotte, additional, Patel, Amita, additional, Hemsley, Carolyn, additional, Goodman, Anna L, additional, Wyncoll, Duncan, additional, Biswas, Jason, additional, Fitzpatrick, Jennifer, additional, Roberts, Lizzie, additional, Millard, James, additional, Stone, Neil, additional, Cape, Angela, additional, Hurley, Lisa, additional, Tam, Chi Kai, additional, Hoyle, Marie-Claire, additional, Maitland, Kate, additional, Trainor, Leona, additional, Reynolds, Helen, additional, Harrison, Jennifer, additional, Anson, Jim, additional, Lewis, Joseph, additional, Folb, Jonathan, additional, Goodwin, Lynsey, additional, Beeching, Nicholas, additional, Dyas, Sarah, additional, Winslow, Helen, additional, Foote, Elizabeth, additional, Roberts, Paul, additional, Natarajan, Pavithra, additional, Chrdle, Alex, additional, Fenech, Manuel, additional, Allsop, Hannah, additional, Austin-Hutchison, Rachel, additional, Barrett, Louise, additional, Brookes, Karen, additional, Carwithen, Leanne, additional, Conbeer, Andrew, additional, Cunningham, Richard, additional, Eglinton, Charlotte, additional, Fok, Rosie, additional, Gott, Hannah, additional, Hughes, Shona, additional, Jones, Lewis, additional, Kalita, Maggie, additional, King, Angela, additional, March, Linda, additional, Marner, Mike, additional, Mynes, Tracey, additional, Plant, Aiden, additional, Price, Suzanne, additional, Sercombe, Judy, additional, Stolton, Alison, additional, Wallis, Mark, additional, West, Marie-Claire, additional, Westcott, Jackie, additional, Williams, Claire, additional, Wosley, Rob, additional, Yabsley, Leona, additional, Butland, Laura, additional, Sorrell, Julie, additional, Mitchell, Tamara, additional, Alli, Abiola, additional, Meiring, James, additional, Masake, Boingotlo, additional, Rowson, Carlene, additional, Smart, Lynne, additional, Makey, Laura, additional, Moll, Sarah, additional, Cunningham, Jane, additional, Ryalls, Kim, additional, Birchall, Kathryn, additional, Middle, Janet, additional, Jackson, Yvonne, additional, Swift, Diane, additional, Cole, Joby, additional, Subramanian, Bala, additional, Okhuoya, Faith, additional, Edwards, Maria, additional, Bailey, Cheryl, additional, Warren, Rebecca, additional, Islam, Gayti, additional, Ankcorn, Michael, additional, Birchall, Sarah, additional, Jones, Paul, additional, Humphries, John, additional, Booth, Stephen, additional, Evan, Cariad, additional, Wyllie, Sarah, additional, Flatt, Andrew, additional, Strakova, Lenka, additional, Hayes, Maria, additional, Valentine, Stacey, additional, James, Clare, additional, Wands, Mary, additional, Cortes, Nicolas, additional, Khan, Nisa, additional, Porter, Robert, additional, Martin, Zoe, additional, Yip, Keith, additional, Preedy, Helen, additional, Chesterfield, Helen, additional, Dobson, Tracey, additional, Walker, Colin, additional, Llewelyn, Martin, additional, Dunne, Angela, additional, Latter, Laura, additional, Porges, Alison, additional, Price, James, additional, Paul, John, additional, Behar, Laura, additional, Robinson, Louise, additional, Murray, Amy, additional, Sargent, Tenessa, additional, Ridley, Carrie, additional, de Gordoa, Laura Ortiz-Ruiz, additional, Gilliam, Deborah, additional, McPherson, Carole, additional, Matthews, Simon, additional, Foreman, Emma, additional, Jarghese, Rajesh, additional, Beddoe, Alisha, additional, Martin, Sebastien, additional, Shaw, Sephora, additional, Wlazly, Dominika, additional, Cole, Maggie, additional, Gihawi, Abraham, additional, Cole, Kevin, additional, Török, M Estée, additional, Gouliouris, Theodore, additional, Bedford, Luke, additional, Saunderson, Rebecca B, additional, Mariolis, Ilias, additional, Bousfield, Rachel, additional, Ramsay, Isobel, additional, Greaves, Daniel, additional, Aliyu, Sani, additional, Cox, Kim, additional, Mlemba, Lois, additional, Whitehead, Lynne, additional, Vyse, Naval, additional, Bolton, Mark, additional, Lambert, Pauline, additional, Chadwick, David, additional, Baillie, Kirsty, additional, Cain, Martyn, additional, Bellamy, Richard, additional, Wong, Jason, additional, Thompson, Jane, additional, Vassallo, Helen, additional, Skotnicka, Agnieszka, additional, Boyce, Andrea, additional, Donnelly, Anthony, additional, FitzGerald, Graham, additional, Dean, Victoria, additional, Warnes, Kristian, additional, Reyes, Anna, additional, Rahman, Saadia, additional, Tsang, Lillian, additional, Williams, Joanne, additional, Morris-Jones, Stephen, additional, Witness, Elen, additional, Brady, Orla, additional, Woodford, Elizabeth, additional, Pettifer, Teresa, additional, McCadden, Angela, additional, Marks, Ben, additional, Collier, Sophie, additional, Mack, Damien, additional, Warren, Simon, additional, Brown, Colin, additional, Lyons, Adrian, additional, Taiyari, Sara, additional, Mepham, Stephen, additional, Sweeney, Anna, additional, Brown, Li-An, additional, Potter, Alison, additional, Mandiza, Jess, additional, Hough, Maxine, additional, Williams, Sue, additional, Renton, Caroline, additional, Walters, Fiona, additional, Nadolski, Maria, additional, Evans, Andree, additional, Tarrant, Polly, additional, Curley, Katherine, additional, Whiteley, Sophie, additional, Halpin, Julia, additional, Hutchings, Melanie, additional, Todd, Shirley, additional, Lohan, Christop, additional, Chapter, Tamika, additional, Folland, Emma, additional, Colville, Alaric, additional, Marden, Katy, additional, Morgan, Marina, additional, Porter, Rob, additional, Baxter, Mel, additional, Rippon, Sarah, additional, Cevik, Muge, additional, Chapman, Judith, additional, Kemp, Tim, additional, Vincent, Rachel, additional, Osborne, Dave, additional, Platt, Tracey, additional, Calderwood, James, additional, Cook, Bernadette, additional, Bedford, Caroline, additional, Galloway-Browne, Leanne, additional, Abberley, Nadine, additional, Attack, Kelly, additional, Allen, Joanna, additional, Harrison, Melanie, additional, Stevenson, Sarah, additional, Brooks, Carol, additional, Harlow, Paula, additional, Ewing, Jordan, additional, Cooper, Shirley, additional, Balancio-Tolentino, Roderick, additional, O'Neil, Laura, additional, Tagney, Rebecca, additional, Shackcloth, Daniela, additional, Fellows, James, additional, Millett, Ruth, additional, Studham, Jo, additional, de Souza, Cherrelle, additional, Howell, Geoffrey, additional, Greaves, Hezron, additional, Foncel, Ella, additional, Kurup, Rahul, additional, Briggs, Jack, additional, Smith, Melody, additional, Suarez, Cristina, additional, Sorrentino, Giordana, additional, Scobie, Antonia, additional, Houston, Angela, additional, Ahmad, Fozia, additional, Breathnach, Aodhan, additional, Chahuan, Rakhee, additional, Wilkins, Katie, additional, Waddington, Natalia, additional, Sharma, Rashmi, additional, Flegg, Peter, additional, Kollipara, Veenu, additional, Alam, Mazhar, additional, Potter, Andrew, additional, Donaldson, Stacey, additional, Armer, Charlote, additional, Frudd, Julie, additional, Joy, Manju, additional, Mathews, Asha, additional, Glass, Stephen K, additional, Ajayi, Ayodele, additional, Fife, Amanda, additional, Qaiser, Saba, additional, Sheehan, Sharon, additional, Muñoz-Villaverde, Sergio, additional, Yogo, Noah, additional, De Abreu, Ines, additional, Notcheva, Gaynor, additional, Flanagan, Joanna, additional, Watson, Cordelia, additional, Sais, Efisia, additional, Adedayo, Adetunji, additional, Chu, Vicky, additional, Shaw, Georgina, additional, Graver, Michelle A, additional, Palmer, Rebecca, additional, Palmer, Donna, additional, Haile, Senait, additional, Gordon, Joanne, additional, Mandar, Kirandip, additional, Szypura, Weronika, additional, Marange, Josephine, additional, Shabangu, Vusumuzi, additional, Moore, Katy, additional, Lyons, Jill, additional, Munang, Melinda, additional, Sangombe, Mirriam, additional, Moran, Ed, additional, Hussain, Abid, additional, Lewszuk, Adam, additional, Batham, Sally, additional, Ellis, Kate, additional, Bahadur, Leila, additional, White, Helena, additional, Pareek, Manish, additional, Sahota, Amandip, additional, Coleman, Stephen, additional, Pateman, Hilary, additional, Kotecha, Atul, additional, Sim, Christopher, additional, Rosser, Andrew, additional, Deane, Jill, additional, Nendick, Richard, additional, Aldridge, Catherine, additional, Clarke, Anne, additional, Wood, Michelle, additional, Marshall, Adele, additional, Stephenson, Lynsey, additional, Matheson-Smith, Tracy, additional, Sloss, John, additional, Potts, Kathryn, additional, Malkin, Joanne, additional, Ftika, Lemonia, additional, Raviprakash, Veena, additional, Malachira, Ahalya, additional, Kean, Miranda, additional, Criste, Kristine, additional, Gladas, Kirsty, additional, Andrews, Caroline, additional, Hutchison, Clare, additional, Adams, Ellen, additional, Andrews, Janet, additional, Romans, Belinda, additional, Ridley, Nicola, additional, Ekani, Melanie, additional, Mitchell, Julie, additional, Smith, Nicola, additional, Clark, Tristan, additional, Glover, Sarah, additional, Reed, Robert, additional, Yam, Tat, additional, Burton, Holly, additional, Said, Rasha, additional, Janvier, Amy, additional, Jacob, Reni, additional, Smalley, Chris, additional, Fair, Alison, additional, Lord, Susan, additional, Ripalda, Kate, additional, Wooldridge, Helen, additional, Cotter, Luis, additional, Cardoso, Gus, additional, Strachan, Elaine, additional, Kaler, Gagan, additional, Mohamoodally, Adam, additional, Lawrence, Emma, additional, Prime, Zoe, additional, Abrahams, Rachel, additional, Price, David Ashley, additional, Rigden, Lesley, additional, Shewan, Laura, additional, Cullen, Katherine, additional, Emmerson, Ingrid, additional, Martin, Karen, additional, Wilson, Hesther, additional, Higham, Charley, additional, Taylor, Kathryn Louise, additional, Ong, Edmund, additional, Patel, Bijal, additional, Bond, Helena, additional, Gradwell, Janine, additional, Widdrington, John, additional, Thornthwaite, Sarah, additional, Prentice, Scott, additional, Poultney, Una, additional, Crowther, Hannah, additional, Fairlamb, Helen, additional, Hetherington, Emily, additional, Brewer, Chris, additional, Banerjee, Suryabrata, additional, Hamson, Clare, additional, McSkeane, Anna, additional, Sharratt, Paula, additional, Thorpe, Joanne, additional, Kimachia, Sue, additional, Wilson, Helen, additional, Jeffs, Benjamin, additional, Masters, Leslie, additional, Wilson, Jonathan, additional, Platt, Judith, additional, Burgess, Lisa, additional, Chadwick, Paul, additional, Jeans, Adam, additional, Keatley, Claire, additional, Moran, Amanda, additional, Swann, Zoe, additional, Pagett, Katherine, additional, Peel, Alex, additional, Howard, Jason, additional, Maloney, Kate, additional, Masdin, Avril, additional, Wright, Louise, additional, Crossman, Samantha, additional, Lowthorpe, Vicki, additional, Moore, Emma, additional, Moss, Peter, additional, Parkin, Angela, additional, Wolstencroft, Adam, additional, Warner, Bev, additional, Tarbotton, Clare, additional, Eyre, Alison, additional, Anderson, Anne, additional, Burdett, Tina, additional, Driffill, Amy, additional, Walker, Ann Sarah, additional, Szubert, Alex, additional, Webb, Helen, additional, Russell, Charlotte, additional, Jackson, Brooke, additional, Otiko, Damilola, additional, Borg, Chiara, additional, Masters, Lindsey, additional, Islam, Zaheer, additional, Díaz-Montaña, Carlos, additional, and Johnson, Debbie, additional

Published
2018
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37. Cancer-Associated IDH1 Promotes Growth and Resistance to Targeted Therapies in the Absence of Mutation

Author

Calvert, Andrea E., primary, Chalastanis, Alexandra, additional, Wu, Yongfei, additional, Hurley, Lisa A., additional, Kouri, Fotini M., additional, Bi, Yingtao, additional, Kachman, Maureen, additional, May, Jasmine L., additional, Bartom, Elizabeth, additional, Hua, Youjia, additional, Mishra, Rama K., additional, Schiltz, Gary E., additional, Dubrovskyi, Oleksii, additional, Mazar, Andrew P., additional, Peter, Marcus E., additional, Zheng, Hongwu, additional, James, C. David, additional, Burant, Charles F., additional, Chandel, Navdeep S., additional, Davuluri, Ramana V., additional, Horbinski, Craig, additional, and Stegh, Alexander H., additional

Published
2017
Full Text
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38. THE RIGHT START

Author

Hurley, Lisa

Subjects
Arts and entertainment industries, Business, Food and beverage industries, Travel industry
Abstract

Byline: Lisa Hurley Beauty and brains make a great combination. And our first issue of 2013 brings you both. The centerpiece of this issue is, as always, our beautiful array [...]

Published
2013

39. THANKS FOR 30

Author

Hurley, Lisa

Subjects
Publishing industry -- Services -- Rites, ceremonies and celebrations, Publishing industry, Arts and entertainment industries, Business, Food and beverage industries, Travel industry
Abstract

Byline: Lisa Hurley As we've noted throughout 2012, this is the 30th anniversary of Special Events. We got our start in 1982 as a little quarterly insert devoted entirely to [...]

Published
2012

40. Come On, Get App-y

Author

Hurley, Lisa

Subjects
Mobile applications -- Surveys -- Evaluation, Professional workers -- Surveys, Arts and entertainment industries, Business, Food and beverage industries, Travel industry
Abstract

Byline: Lisa Hurley Two years ago, Special Events polled event professionals to see which mobile apps make their lives easier. But two years is two eons in the tech world, [...]

Published
2012

41. WHERE WERE YOU IN '82?

Author

Hurley, Lisa

Subjects
Arts and entertainment industries, Business, Food and beverage industries, Travel industry
Abstract

Byline: Lisa Hurley Thirty years ago, Ronald Reagan was in the White House, 'Cats' opened on Broadway, and a gallon of gasoline cost $1.30. It was also the year that [...]

Published
2012

42. Green Power

Author

Hurley, Lisa

Subjects
Lease and rental services industry -- Customer relations -- Officials and employees -- Rites, ceremonies and celebrations, Company business management, Arts and entertainment industries, Business, Food and beverage industries, Travel industry
Abstract

Byline: Lisa Hurley Larry Green, head of Rentals Unlimited, knows what his catering clients need. He should. Before he launched his rental company, he was a caterer - for a [...]

Published
2012

43. Hit Trends In Corporate Acts

Author

Hurley, Lisa

Subjects
T. Skorman Productions Inc. -- Officials and employees, Entertainment industry -- Officials and employees, Arts and entertainment industries, Business, Food and beverage industries, Travel industry
Abstract

Byline: Lisa Hurley THE RIGHT ACT PLAYS ANYWHERE WHO: PAUL CREIGHTON, CSEP, T. SKORMAN PRODUCTIONS, ORLANDO, FLA. WWW.TSKORMAN.COM WHAT'S PLAYING: 'Headliners are still strong, and acts that segment their performances [...]

Published
2012

44. BETTER, BUT

Author

Hurley, Lisa

Subjects
Event planning -- Economic aspects, Stock markets -- Forecasts and trends, Special events -- Economic aspects, Stock market, Market trend/market analysis, Arts and entertainment industries, Business, Food and beverage industries, Travel industry
Abstract

Byline: Lisa Hurley I track my family's finances in Quicken, and charting my own little economy pretty well mirrors what's happening on a grand scale. My portfolio will show some [...]

Published
2012

45. New Beat for The Heart Ball Has the Beat

Author

Hurley, Lisa

Subjects
Fund raising, Fund raising events -- Planning, Company business planning, Arts and entertainment industries, Business, Food and beverage industries, Travel industry, American Heart Association -- Rites, ceremonies and celebrations
Abstract

Byline: Lisa Hurley Fundraisers with a legacy resent their own unique challenge. It's risky to tinker with a successful formula, but without some intriguing new tweaks, even loyal supporters might [...]

Published
2012

46. One From The Heart

Author

Hurley, Lisa

Subjects
Event planners -- Officials and employees, Company business management, Arts and entertainment industries, Business, Food and beverage industries, Travel industry
Abstract

Byline: Lisa Hurley Successful careers are often born out of passion for the work itself. And this certainly describes the career arc of Bryan Rafanelli, CEO of Boston-based Rafanelli Events. [...]

Published
2012

47. Wedding Planning PLUS

Author

Hurley, Lisa

Subjects
Event planners -- Services, Arts and entertainment industries, Business, Food and beverage industries, Travel industry
Abstract

Byline: Lisa Hurley THE ENTERTAINMENT EXPERT TARA WILSON, TARA WILSON EVENTS www.tarawilson.com Tara Wilson began positioning herself as an 'entertainment expert' back in 2007, the same year she launched her [...]

Published
2012

48. WHAT'S NEEDED NEXT

Author

Hurley, Lisa

Subjects
Special events -- Forecasts and trends, Market trend/market analysis, Arts and entertainment industries, Business, Food and beverage industries, Travel industry
Abstract

Byline: Lisa Hurley 'Never make predictions,' baseball great Casey Stengel once cautioned, 'especially about the future.' I think about this warning every time Special Events releases one of our big [...]

Published
2012

49. 14TH ANNUAL30 TOP RENTAL COMPANIES

Author

Hurley, Lisa

Subjects
Event planners -- Rankings -- Services, Lease and rental services industry -- Rankings -- Services, Arts and entertainment industries, Business, Food and beverage industries, Travel industry
Abstract

Byline: EDITED BY LISA HURLEY AZTEC EVENTS & TENTS/SHAFFER SPORTS & EVENTS Houston WEBSITE www.aztecusa.com TOP OFFICERS Todd Johnson, Scott McShan, COMPANY BASICS Since its founding in 1982, this tent [...]

Published
2011

50. FUNDS ZONE

Author

Hurley, Lisa

Subjects
Periodical publishing -- Economic aspects -- Services, Arts and entertainment industries, Business, Food and beverage industries, Travel industry
Abstract

Byline: Lisa Hurley While the recession didn't eat into the budgets of fundraising galas as badly as it did corporate events, 'Budgets have remained flat with some [gala] clients and [...]

Published
2011

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