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Atypical teratoid/rhabdoid tumor (AT/RT) is well documented in children but less so in adults because of its rarity. We report a series of five cases, a literature review and quantitative analysis of the survival outcome of adult AT/RT patients. Seventy-four patients including our five cases (male: female = 16: 58) were evaluated, whose median age was 32.5 years (18–80 years). The commonest location was the sellar region. Median overall survival (OS) was 12.5 months (0.5–204.00 months). Chemotherapy was associated with OS (HR: 0.349, 95%CI: 0.176–0.694, p = 0.003), while other factors did not influence OS. From Kaplan-Meier analysis, surgery combining postoperative chemotherapy and radiotherapy was associated with better prognosis (Log Rank: χ2 = 14.662, p = 0.001). Adult AT/RT is commoner in females and tends to recur rapidly after surgical resection. Chemotherapy may provide a survival benefit. Surgery combined with postoperative chemotherapy and radiotherapy was associated with better prognosis for adult AT/RT patients, though the overall prognosis was still poor. [ABSTRACT FROM AUTHOR]

Objective: To investigate the effect of locking plate internal fixation for the treatment of proximal lateral femoral wall fracture., Methods: From January 2021 to June 2022, 31 patients with intertrochanteric fractures and lateral wall fractures were treated. Among them, 15 patients were treated with proximal femoral nail antirotation (PFNA) fixation including 3 males and 12 females with an average age of (75.87±7.46) years old;the other 16 patients were treated with 3.5 mm pre-curved screw locking plate fixtion for lateral wall fracture including 4 males and 12 females with an average age of (76.15±9.47) years old. After surgery, the surgical index, tip-apical distance(TAD), postoperative standing weight-bearing time, and fracture reduction were compared between two groups. Postoperative hip function was evaluated according to Harris hip score., Results: All patients were followed up for an average of (12±5) months ranging from 7 to 17 months. The immediate postoperative neck angle ranged from 111° to 132°(119.3±8.3)°. Fracture reduction results were excellent in 11 cases, fair in 2, worse in 1 in PFNA group;excellent in 12, fair in 3, worse in 1 in PFNA+locking plate group. One case of the PFNA group had a spiral blade cut out through the femoral head. There were significant differences in the time of operation, the amount of blood loss during the operation, the length of incision between two groups( P <0.05). There was no significant difference in TAD and postoperative standing weight-bearing time between two groups( P >0.05). There were significant differences in Harris scores at 6 months after surgery between two groups( P <0.05)., Conclusion: The application of PFNA-assisted locking plate in the treatment of femoral intertrochanteric fractures with lateral wall fractures is effective, and can restore the integrity of lateral wall, improve the stability of PFNA internal fixation, and reduce postoperative complications.