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Since the Tenth Five-Year Plan, the litho-stratigraphic reservoir has been the key area that contributes to China petroleum exploration and increase of oil reserves and production, with proved reserves accounting for 80%. In this study, lithologic reservoir formation model of three types of slope basin, three types of sag basin and three types of their combination have been constructed through typical reservoir analysis, new experimental analysis technique application, physical simulation of hydrocarbon reservoir accumulation mechanism, formation and distribution models of oil and gas reservoirs of six basins that distributed in eastern, middle and western of China. This paper not only reveals the formation mechanism and major controlling factors of lithologic reservoirs, but also creates a method of evaluating giant oil and gas province. Main controlling factors and accumulation rules of two main types of stratigraphic reservoirs which are lithologic pinchout type and weathering crust karst type are discussed,and their evaluation methods are established. litho-stratigraphic reservoirs enrichment rules of four types of basin are further understood, the specified evaluation and delicate exploration technique are formed and the exploration direction of Thirteenth Five-Year Plan is defined.The research in this paper has supported evaluation and selection of oil and gas pools, promoting litho-stratigraphic reservoir exploration. [ABSTRACT FROM AUTHOR]