Search

Your search keyword '"HORTON, ELIZABETH D."' showing total 14 results
Start Over Author "HORTON, ELIZABETH D."
14 results on '"HORTON, ELIZABETH D."'

1. Exercise, unlike insulin, promotes glucose transporter translocation in obese Zucker rat muscle

Author

King, Patricia A., Betts, Jeffery J., Horton, Elizabeth D., and Horton, Edward S.

Subjects
Rats -- Research, Membranes (Biology) -- Analysis, Exercise -- Influence, Glucose metabolism -- Observations, Insulin resistance -- Analysis, Biological sciences
Abstract

The transfer of glucose, which is induced by the influence of insulin, is determined by analyzing animal models such as the rat. The effects of exercise on the animal and the muscle contraction caused by exercise on the transfer of cellular glucose are not evident. The augmentation of the Vmax varies with the size of the rats. The muscles in obese rats exhibit an unsuccessful total transporter translocation, resulting in a fall in the response.

Published
1993

2. Exercise training increases GLUT-4 protein in rat adipose cells

Author

Hirshman, Michael F., Goodyear, Laurie J., Horton, Elizabeth D., Wardzala, Lawrence J., and Horton, Edward S.

Subjects
Fat cells -- Composition, Blood sugar -- Research, Biological sciences
Abstract

The determination of the relative abundance and subcellular distribution of the GLUT-1 and GLUT-4 glucose transformer isoforms in basal and insulin-stimulated adipose cells from wheel cage exercise-trained rats enables the comparison with both age matched sedentary controls and young cell size matched sedentary controls. The translocation of GLUT-4 to the plasma membrane from an intracellular pool causes the increased rate of insulin-stimulated glucose transport in adipose cells from exercise trained rats.

Published
1993

14. Acute exercise increases the number of plasma membrane glucose transporters in rat skeletal muscle

Author

Hirshman, Michael F., Wallberg-Henriksson, Harriet, Wardzala, Lawrence J., Horton, Elizabeth D., and Horton, Edward S.

Abstract

To determine whether increased glucose transport following exercise is associated with an increased number of glucose transporters in muscle plasma membranes, the D‐glucose inhabitable cytochalasin B binding technique was used to measure glucose transporters in red gastrocnemius muscle from exercised (1 h treadmill) or sedentary rats. Immediately following exercise there was a 2‐fold increase in cytochalasin B binding sites, measured in purified plasma membranes enriched 30‐fold in 5′‐nucleotidase activity. This increase in glucose transporters in the plasma membrane may explain in part, the increase in glucose transport rate which persists in skeletal muscle following exercise. Where these transporters originate, remains to be elucidated.

Published
1988
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results