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628 results on '"HELLIGE, G."'

11. Posters

Author

Török, T., Kardos, A., Rudas, L., Paprika, D., McLuckie, A., Beale, R. J., Bihari, D., Keller, H., Seltzer, N., Weimer, A., Menning, H., Ulrich, P., Staedt, U., Kirschstein, W., Kasai, T., Endo, S., Arakawa, N., Sato, N., Suzuki, T., Taniguchi, S., Inada, K., Hiramori, K., Schmidt, W., Meineke, I., Nottrott, M., Frerichs, I., Müller, S., Hellige, G., De Blasio E., De Sio A., Sibilio G., Papa A., Golia D., Grassia V., Bove G., Zehelgruber, M., Mundigler, G., Christ, G., Merhaut, C., Klaar, U., Kratochwill, C., Hofmann, S., Siostrzonek, P., Suarez, F., Corrales, M., Rábago, R., Gonzalez-Arenas, P., Morales, R., Sanchez J., Fraile, J., Rey, M., Martinell, J., Niederst, P. -N., Mellwig, K. -P., Schmidt, H. K., Gleichmann, U., Körfer, R., Di Bartolomeo, S., Bertolissi, M., Nardi, G., De Monte, A., Janssens, U., Ochs, J. -G., Klues, H. G., Hanrath, P., Sajjanhar, T., Tibby, S. M., Hatherill, M., Anderson, D., Murdoch, I. A., Krivec, B., Voga, G., Žuran, I., Skale, R., Parežnik, R., Podbregar, M., Bonnefoy, E., Chevalier, P., Kirkorian, G., Guidolet, J., Marchand, A., Bouchayer, D., Marcaz, P. Bert, Touboul, P., Welte, T., Molling, J., Jepsen, M. S., Claus, G., Klein, H., Cinnella, G., Dambrosio, M., Brienza, N., Conte, M., Maggiore, S. M., Leone, A. M., Brienza, A., DiVenere, N., Vandewoude, K., Poelaert, J., Vogelaers, D., Garcia, R. Blanca, Buylaert, W., Roosens, C., Colardyn, F., Annane, D., Béllissant, E., Pussard, E., Asmar, R., Lacombe, F., Lanata, E., Madonna, O., Safar, M., Giudicelli, J. F., Raphael, J. C., Gajdos, Ph., Mattys, M., Dumont, L., Annaert, J. F., Mardirosoff, C., Goldstein, J., Verbeet, T., Massaut, J., Haas, N. A., Uhlemann, F., Daehnert, I., Berger, F., Stiller, B., Dittrich, S., Schulze-Neick, I., Eweit, P., Lange, P. E., Langenherp, C. J. M., Pietersen, H., Geskes, G., Wagenmakers, A., Soeters, P., Maggiorini, M., Brimioulle, S., Lejeune, P., Delcroix, M., Vermeulen, F., Stephanazzi, J., Naeije, R., Kunert, M., Stolzenburg, H., Scheuble, L., Emmerich, K., Ulbricht, L. J., Krakau, I., Gülker, H., Broch, M. J., Valentín, V., Murcia, B., Bartual, E., Málaga, A., Miralles, L. L., Valls, F., Wallin, C. J., Sidenö, B., Vaage, J., Leksell, L. G., Stuchlinger, H. G., Seidler, D., Hollenstein, U., Janata, K., Muellner, M., Loeffler, W., Gamper, G., Bur, A., Malzer, R., Laggner, A. N., Hirschl, M. M., Binder, M., Herkner, H., Bur, A., Laggner, A. N., Turani, F., Ceraso, C., Lironcurti, A., Senesi, P., Leonardis, C., Sabato, A. F., Pietersen H. G., Langenberg C. J. M., Geskes G., Wagenmakers A. J. M., de Lange S., Soeters P. B., Royira, A., Oussedik, L., Cambray, C., Glmeno, C., Cerda, M., Sanchez, Ma. A., Lesmes, A., Guerrero, M., Vigil, E., Ortega, F., Lucena, F., Righini, E. R., Alvisi, R., Marangoni, E., Gritti, G., Ordóñez, A., Hernández, A., Pérez-Bernal, J., Hinojosa, R., Borrego, J. M., Franco, A., López-Barneo, J., Pérez-Bernal, J., Gutiérrez, E., Hinojosa, R., Hernández, A., Borrego, J. M., Cerro, J., Rincón, D., Ordóñez, A., Martin, R., Saussine, M., Sany, C. L., Calvet, B., Raison, D., Frapier, J. M., Wallin, C. -J., Olsson, Å., Nordländer, R., Leksell, L. G., Vasilkov, V., Safronov, A., Marinchev, V., Rodrigues, A. C., Moraes, A., Galas, F., Angelim, V., Medeiros, C., Auler, J. O., Bellotti, G., Pilleggi, F., Carmona, M. J., Messias, E. R. R., Joseph, D., Baigorri, F., Artigas, A., Blanch, L., Wagner, F., Dandel, M., Günther, G., Schulze-Neick, I., Weng, Y., Loebe, M., Hetzer, R., Colreavy, F., Balea, M., Cahalan, M., Carpintero, JL., de la Fuente, M. C., Estecha, M. A., Molina, J. M., del Fresno, L. R., Daga, D., Toro, R., Poullet, A., de la Torre, M. V., Garcia, A. J., Michalopoulos, A., Rellos, K., Skambas, D., Liakopoulos, O., and Geroulanos, S.

Published
1996
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12. Electrical impedance tomography in monitoring experimental lung injury

Author

Frerichs, I., Hahn, G., Schroder, T., and Hellige, G.

Subjects
Impedance (Electricity) -- Usage, Oleic acid -- Research, Swine -- Research, Lungs -- Abscess, Lungs -- Diagnosis, Lungs -- Research, Health care industry
Abstract

Byline: I. Frerichs (1), G. Hahn (1), T. Schroder (1), G. Hellige (1) Keywords: Key words Lung injury; Oleic acid; Regional ventilation; Electrical impedance; Pig Abstract: Objective: To apply electrical impedance tomography (EIT) and the new evaluation approach (the functional EIT) in monitoring the development of artificial lung injury. Design: Acute experimental trial. Setting: Operating room for animal experimental studies at a university hospital. Subjects: Five pigs (41.3 +- 4.1 kg, mean body weight +- SD). Interventions: The animals were anaesthetised and mechanically ventilated. Sixteen electrodes were attached on the thoracic circumference and used for electrical current injection and surface voltage measurement. Oleic acid was applied sequentially (total dose 0.05 ml/kg body weight) into the left pulmonary artery to produce selective unilateral lung injury. Measurements and results: The presence of lung injury was documented by significant changes of PaCO.sub.2 (40.1 mmHg vs control 37.1 mmHg), PaO.sub.2 (112.3 mmHg vs 187.5 mmHg), pH (7.35 vs 7.42), mean pulmonary arterial pressure (29.2 mmHg vs 20.8 mmHg) and chest radiography. EIT detected 1) a regional decrease in mean impedance variation over the affected left lung (--41.4 % vs control) and an increase over the intact right lung ( + 20.4 % vs control) indicating reduced ventilation of the affected, and a compensatory augmented ventilation of the unaffected lung and 2) a pronounced fall in local baseline electrical impedance over the injured lung (--20.6 % vs control) with a moderate fall over the intact lung (--10.0 % vs control) indicating the development of lung oedema in the injured lung with a probable atelectasis formation in the contralateral one. Conclusion: The development of the local impairment of pulmonary ventilation and the formation of lung oedema could be followed by EIT in an experimental model of lung injury. This technique may become a useful tool for monitoring local pulmonary ventilation in intensive care patients suffering from pulmonary disorders associated with regionally reduced ventilation, fluid accumulation and/or cell membrane changes. Author Affiliation: (1) Department of Anaesthesiological Research, Centre of Anaesthesiology, Emergency and Intensive Care Medicine TL 195, University of Gottingen, Robert-Koch-Strasse 40, D-37 075 Gottingen, Germany Tel.: + (49)551/39--5919 Fax: + (49)/551/39--8676, DE Article note: Received: 22 December 1997 Accepted: 7 April 1998

Published
1998

24. Nephrologie I

Author

Paßlick, J., Chlebowski, H., Trapp, R., Grabensee, B., Lauster, F., Segerer, W., Arenz, F., Gurland, H. J., Eigler, J., Schafferhans, K., Heidbreder, E., Götz, R., Heidland, A., Schilling, G., Reuschenbach, Ch., Klehr, U., Simon, H. J., Klaus, D., Lederle, R. M., Wernze, H., Buschmann, S., Daul, A., Graben, N., Bock, K. D., Brodde, O.-E., Kramer, P., Rösick, F., Rosenkranz, W., Hellige, G., Scheler, F., Weber, M., Köhler, H., Manns, M., Meye zum Büschenfelde, K.-H., Miehlke, Klaus, editor, and Bergmann, J. F.

Published
1984
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35. Perkutane Herz-Lungen-Maschine bei Koronarangioplastie von Risiko- und Notfallpatienten

Author

Bock H, J. P. Hering, Mohr Fw, Heinrich Kreuzer, Hellige G, Hans R. Figulla, and K. H. Scholz

Subjects
medicine.medical_specialty, Resuscitation, Percutaneous, business.industry, Unstable angina, medicine.medical_treatment, Cardiogenic shock, education, 030208 emergency & critical care medicine, General Medicine, 030204 cardiovascular system & hematology, medicine.disease, 3. Good health, Angina, 03 medical and health sciences, 0302 clinical medicine, medicine.anatomical_structure, Internal medicine, Angioplasty, medicine, Cardiology, Myocardial infarction, business, Artery
Abstract

Using a recently developed, percutaneously introduced cardiopulmonary support system (PCPS) seven high-risk patients (four men, three women; mean age 61 [41-77] years) underwent percutaneous transluminal coronary angioplasty. In one patient, with unstable angina and in incipient cardiogenic shock, perfusion with PCPS was begun immediately before coronary angioplasty. In six patients it was undertaken with the PCPS on stand-by, but eventually not needed. Coronary angioplasty was successful in six patients, partially successful in one. Angina was considerably improved long-term in all patients, but one of them died 2.5 months afterwards at home. In two other patients (men, aged 41 and 71 years) with acute myocardial infarction, the PCPS was employed under circumstances of emergency resuscitation. In both cases recanalization of the occluded coronary artery was achieved mechanically during perfusion with PCPS; one patient survived. Availability of PCPS, also in an emergency, makes it possible to extend the indications for coronary angioplasty to include even high-risk patients.

Published
2008
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36. Hämodynamische Begleiterscheinungen intrakoronarer Injektionen eines neuen lungengängigen Ultraschallkontrastmittels

Author

Hering Jp, Hellige G, and T. Schröder

Subjects
Left ventricular contraction, medicine.medical_specialty, business.industry, Hemodynamics, Blood flow, 3. Good health, Contrast medium, Drug concentration, Blood pressure, Concomitant, Internal medicine, Cardiology, Medicine, Radiology, Nuclear Medicine and imaging, business, Hemodynamic effects
Abstract

AIM A new transpulmonary echo contrast agent (SH U 508) was injected intracoronally to six anaesthetised sheep to examine its possible direct cardiac effects. METHOD SH U 508 was injected in randomised order in three different volumes (2, 4 and 8 ml; n = 12, 10, 9) with the same drug concentration of 200 mg/ml. RESULTS The 2 ml and 4 ml injections had no relevant effect on the arterial, pulmonary-arterial and ventricular pressures, on the left ventricular contraction velocity and on the myocardial blood flow (less than +/- 10% of the control value). The left ventricular relaxation velocity decreased by 20%. The disturbance of the left ventricular relaxation at a volume of 8 ml was pronounced (about 40% decrease). Slight left ventricular dysfunction further manifested itself in a decreased systolic pressure (-15%) and increased left ventricular enddiastolic pressure (20%). CONCLUSION In summary the overall effect of the intracoronary injections of SH U 508 exhibited only minor cardiac side effects. If the current results are extrapolated to peripheral-venous application, the clinically required central-venous 8 ml injection of a 400 mg/ml suspension is not expected to produce any coronary haemodynamic side effects, due to drug dilution in the pulmonary circulation and resulting low intra-coronary concentrations.

Published
2008
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