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Focusing on the problem of high efficiency resource scheduling in cloud computing environment, since current re source scheduling algorithm had been less given consideration to the shortest completion time and the least cost of the services, this paper designed the fitness function which could comprehensive response the time and cost, and proposed an estimation of distribution-shuffled frog leaping algorithm (EDSFLA). This algorithm redefined the evolutional operators of shuffled frog lea ping algorithm (SFLA), utilizing the cross operators of genetic algorithm, targeted in applying to scheduling problem with integer-coded. EDSFLA introduced evolutionary strategy of estimation of distribution to break the confine of search pattern in the standard SFLA, ad made the learning ability of this algorithm more comprehensive. Experimental results show that this algorithm has more capability in convergence and searching ability compared with the standard SFLA and EDA in solving cloud resource scheduling problems. [ABSTRACT FROM AUTHOR]

Purpose: The aim of present study was to explore the effect of strontium ranelate (SrR) on the proliferation and chondrogenic differentiation of rat bone mesenchymal stem cells (BMSCs)., Methods: Rat BMSCs were isolated and cultured in chondrogenic differentiation medium containing 0.25-2.0 mmol/L strontium ranelate. CCK-8 assay was used to study the influence of cell proliferation. Toluidine blue staining and alizarin blue staining were used to observe chondrogenic differentiation. Quantitative hydroxyproline (Hyp) activity assay was conducted. PCR and Western blots were used to detect the expression of related genes and proteins. Statistical analysis was performed using SPSS 22.0 software package., Results: 0.25 mmol/L strontium ranelate did not inhibit the proliferation of BMSCs and promote the expression of chondroitin sulfate and proteoglycan. Hyp assay showed a higher content of collagen fibers in extracellular matrix in 0.25 mmol/L SrR treatment group. PCR and WB also showed up-regulated expression of Sox-9, Col-Ⅱ gene and protein, Aggrecan protein, and suppressed expression of MMP-9 gene., Conclusions: 0.25 mmol/L SrR could significantly promote chondrogenic differentiation of BMSCs.

Purpose: To investigate the effect of ball attachments with different materials on retention of mandibular implant supported overdenture., Methods: The experimental groups were divided into group A (titanium ball / titanium cap group) and group B (titanium ball / golden cap group), each group had 3 samples. A standard mandibular edentulous model was made, and the implants (4.8*10 RN SP) were embedded in the bilateral canine region. Mandibular complete dentures were made routinely and the attachments were attached. Five thousand times of insertion-separation cycles were carried out. After 200 times of cycles, the retention force was tested. The difference between 2 groups was compared by using SPSS 13.0 software package. The change of positive structure surface morphology was observed under scanning electron microscope at the beginning and the end of the experiment., Results: The retention force of group A decreased from （27.00±0.16） N to （4.18±0.03） N, and the retention force of group B decreased from （21.58±0.06） N to （19.15±0.06）N. Decay of retention of group A was significantly greater than that of group B. At the end of the experiment, the globular structure of group A was severely broken, while a smooth and clear spherical structure was displayed in group B., Conclusions: The retention of mandibular implant supported overdenture decreases with the increase of insertion-separation times. The decay of retention force is related to destruction of positive structure surface. The fatigue resistance of the precious metal material is better.