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2. Coupled hydro-chemo-mechanical model for fault activation under reactive fluid injection

Author

H. Tounsi, Ahmad Pouya, and Jeremy Rohmer

Subjects
Environmental Engineering, Petroleum engineering, Chemo mechanical, 0211 other engineering and technologies, Numerical modeling, 02 engineering and technology, Reactive fluid, Fault (power engineering), 021105 building & construction, Caprock, Dissolution, Geology, 021101 geological & geomatics engineering, Civil and Structural Engineering, Leakage (electronics)
Abstract

Pre-existing faults cross-cutting caprock formations constitute potential leakage pathways during geological CO2 sequestration. When the fault filling material is calcite-rich, dissolution of the f...

Published
2020
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3. Numerical Modeling of Coupled Thermal-Hydro-Mechanical Processes in Salt Formations for Geologic Disposal of Large Nuclear Waste Canisters

Author

H. Tounsi, J. Rutqvist, M. Hu, R. Wolters, and L. Blanco-Martín

Abstract

ABSTRACT: Salt has long been considered as a potential host rock for the geological disposal of radioactive waste because of its favorable properties, including self-sealing, low permeability and high thermal conductivity. The feasibility of nuclear waste disposal within salt formations has been investigated mainly for small-sized canisters, widely considered in many national nuclear waste disposal programs. Direct disposal of larger-sized canisters originally designed for spent nuclear fuel storage and transportation has lately been examined as a promising and cost-effective alternative. However, the amount of decay heat released by large canisters may cause high temperature in the backfill surrounding the canisters and in the host rock. This results in pressure and stress changes that may affect the long-term repository performance. To analyze it, the TOUGH-FLAC simulator is used to conduct fully coupled Thermal-Hydro-Mechanical (THM) simulations of a generic salt repository for large-sized canisters. In this code, large deformation has been considered allowing to accommodate viscous compaction of the crushed salt backfill as well as the long-term stress changes in salt host rock. The simulations show that the peak temperature in the backfill and in the host rock can be reduced by adjusting the distance between the canisters along emplacement tunnels or the spacing between the tunnels themselves. Nevertheless, the thermal pressurization in the salt host rock and in the crushed salt backfill, following the reconsolidation of the backfill, seems to be less sensitive to these spacing adjustments. Consequently, the pore-pressure could potentially exceed the lithostatic stress causing an increase of permeability and a fluid infiltration into the rock mass that may last more than 1000 years after the waste canister emplacement. Thus, it is critically important to analyze and manage these coupled THM processes for a safe and effective disposal of nuclear waste in salt formations. 1 INTRODUCTION Geologic disposal of large-sized canisters, originally designed for spent nuclear fuel storage and transportation, has lately been examined as a promising and cost-effective alternative to conventional smaller-scale canisters commonly considered in many national nuclear waste disposal programs (Hardin et al., 2015).

Published
2022
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8. Mucocutaneous involvement in behçet’s disease

Author

Z. alaya, R amri, A. fraj, I. chaabane, W. Garbouj, M. medhioub, M. loukil, and H. tounsi

Abstract

Behçet's disease is a chronic inflammatory disease characterized by its clinical polymorphism associating mucocutaneous involvement to systemic manifestations. The mucocutaneous lesions are considered the hallmark of the disease, being the most common symptoms presenting at the onset of disease. Our objective was to determine the characteristics of this skin involvement during Behçet's disease. We conducted a descriptive study over a period of 30 years, having collected all patients with Behçet's disease. These were 98 patients. A male predominance was observed in our studied population with a Sex Ratio of 2.5. The mean age at diagnosis was 34 years. Mucocutaneous involvement was observed in all patients. Oral aphthosis was constant and genital ulcers, were observed in 81 cases. The other mucocutaneous manifestations were: pseudofolliculitis (61 cases), erythema nodosum (7 cases), skin ulcers (4 cases), acneiform lesions (2 cases), perianal ulcers (1 case), skin ulceration (1 case) and erythema multiforme. (1 case). All of our patients were treated with colchicine. Corticosteroids and non-steroidal anti-inflammatory drugs were each indicated in one case for resistant forms.

Published
2020
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12. Thermo-hydro-mechanical modeling of artificial ground freezing taking into account the salinity of the saturating fluid

Author

H. Tounsi, Emad Jahangir, Ahmed Rouabhi, Centre de Géosciences (GEOSCIENCES), MINES ParisTech - École nationale supérieure des mines de Paris, and Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)

Subjects
Capillary pressure, Ground freezing, Computation, 0211 other engineering and technologies, 02 engineering and technology, Mechanics, 010502 geochemistry & geophysics, Geotechnical Engineering and Engineering Geology, 01 natural sciences, Stability (probability), Computer Science Applications, [SPI.MAT]Engineering Sciences [physics]/Materials, Salinity, [SPI.GCIV]Engineering Sciences [physics]/Civil Engineering, 13. Climate action, Latent heat, Environmental science, Porous medium, Saline groundwater, ComputingMilieux_MISCELLANEOUS, 021101 geological & geomatics engineering, 0105 earth and related environmental sciences
Abstract

The modeling of Artificial Ground Freezing in geotechnical engineering applications has two main objectives, the first is the prediction of the extent of the frozen zone around the cooling sources (Thermo-Hydraulic models) and the second is the prediction of the ground’s deformations and the site stability (Thermo-Hydro-Mechanical models). Reliable predictions require the consideration of unfavorable hydro-geological conditions such as high seepage velocities, ground heterogeneity and saline groundwater that may negatively influence the performance of AGF. The influence of the saturating fluid salinity on the THM behavior of the ground during freezing is the less documented point among the three and is therefore the subject of this paper. To this end, a fully coupled THM model considering the salinity effect has been derived. The formalism is completely thermodynamically consistent and introduces some simplifying assumptions, especially to describe phase change terms (capillary pressure and latent heat), in order to achieve a mathematical formulation that can be easily handled by computation software. Stress-free freezing laboratory tests carried out on specimens initially fully saturated with sodium chloride solutions at three different concentrations allowed to validate the proposed approach and to highlight some key mechanisms associated with the phase change of saline-saturated porous media.

Published
2020
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13. Mechanical behavior of frozen metapelite: Laboratory investigation and constitutive modeling

Author

H. Tounsi, Ahmed Rouabhi, Fabien Guérin, Emad Jahangir, Centre de Géosciences (GEOSCIENCES), MINES ParisTech - École nationale supérieure des mines de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL), and ORANO

Subjects
Dilatant, Materials science, Ground freezing, 010504 meteorology & atmospheric sciences, 0211 other engineering and technologies, 02 engineering and technology, Strain hardening exponent, Geotechnical Engineering and Engineering Geology, Triaxial shear test, Overburden pressure, 01 natural sciences, [SPI.MAT]Engineering Sciences [physics]/Materials, Infiltration (hydrology), [SPI.GCIV]Engineering Sciences [physics]/Civil Engineering, Phenomenological model, Hardening (metallurgy), General Earth and Planetary Sciences, Geotechnical engineering, ComputingMilieux_MISCELLANEOUS, 021101 geological & geomatics engineering, 0105 earth and related environmental sciences
Abstract

Artificial ground freezing has been used in the mine of Cigar Lake to mitigate groundwater infiltration to underground mining operations and stabilize the heterogeneous and poor ground. In addition to the control of the freezing process, the ability to predict accurately the ground movements and the site stability is crucial to a successful use of this technique. This requires developing adequate constitutive models able to correctly reproduce the mechanical behavior of water-saturated soils at low temperatures. To achieve this goal, a digital control servo-hydraulic triaxial test facility with full data acquisition has been developed, and an experimental program was carried out to investigate the mechanical behavior of metapelite samples collected from the mine of Cigar Lake. A series of triaxial compression tests were conducted on reconstituted and natural frozen metapelite specimens under different strain rates (2.5, 4.5 and 8 × 10−6 s−1) and at different temperatures (−10, −20 and −30 °C) and confining pressures (1, 5 and 9 MPa). The experimental results showed that the stress-strain behavior of frozen metapelite, in the studied range of temperature and confining pressure, is elasto-viscoplastic, strain hardening, highly sensitive to temperature and moderately sensitive to the confinement level. They also proved that the transition contractancy-dilatancy is significantly dependent on temperature and suggested the existence of a critical temperature between −20 and −10 °C that represents a dilatancy threshold. To capture these observations, a recent phenomenological model developed for crystalline rocks was used. The model accounts for the phenomena of hardening, dilatancy/contractancy and time dependency and was extended to include the effect of temperature on the frozen material's distorsion and on the dilatancy onset. The proposed model was validated using the triaxial compression tests on metapelite and experimental results from literature on frozen sand.

Published
2020
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14. Thermo-Hydro-Mechanical Modeling of Artificial Ground Freezing: Application in Mining Engineering

Author

Fabien Guérin, H. Tounsi, Ahmed Rouabhi, Michel Tijani, Centre de Géosciences (GEOSCIENCES), MINES ParisTech - École nationale supérieure des mines de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL), and ORANO

Subjects
Waterproofing, Ground freezing, 010504 meteorology & atmospheric sciences, Mechanical impact, 0211 other engineering and technologies, Geology, Excavation, 02 engineering and technology, [SPI.MECA.MSMECA]Engineering Sciences [physics]/Mechanics [physics.med-ph]/Materials and structures in mechanics [physics.class-ph], Geotechnical Engineering and Engineering Geology, 01 natural sciences, Pore water pressure, [SPI.GCIV]Engineering Sciences [physics]/Civil Engineering, Long period, Ground temperature, Soil stabilization, Environmental science, Geotechnical engineering, 021101 geological & geomatics engineering, 0105 earth and related environmental sciences, Civil and Structural Engineering
Abstract

International audience; For decades, artificial ground freezing (AGF) has been used as a temporary soil stabilization and waterproofing technique in multiple geotechnical engineering applications. Experience gained from AGF experiments indicates that the pore water expansion during freezing and the resulting pressure have the potential to induce ground movements in adjacent nonfrozen areas. This process was investigated in this paper using a comprehensive set of in situ temperature and displacement monitoring data collected in the Cigar Lake underground mine, Canada. The data set allowed to investigate the mechanical impact of freezing on a mine tunnel and prompted the need to derive a fully coupled thermo-hydro-mechanical model to predict ground temperature and displacements. Thermodynamically consistent, the model developed for this study is based on a macroscopic continuum approach and uses simplifying assumptions to overcome the computational difficulties associated with the modeling of complex mining environments over a long period of time. This model was used to perform three-dimensional finite-element simulations of the ground freezing and excavation activities in the Cigar Lake mine, showing good agreement with field measurements.

Published
2019
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15. 3D Numerical modeling of artificial ground freezing in mining engineering

Author

H. Tounsi, Michel Tijani, Fabien Guérin, Ahmed Rouabhi, Centre de Géosciences (GEOSCIENCES), MINES ParisTech - École nationale supérieure des mines de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL), ORANO, and ITA-AITES

Subjects
[SPI.GCIV]Engineering Sciences [physics]/Civil Engineering, Ground freezing, 0211 other engineering and technologies, Numerical modeling, Geotechnical engineering, 02 engineering and technology, [SPI.MECA.MSMECA]Engineering Sciences [physics]/Mechanics [physics.med-ph]/Materials and structures in mechanics [physics.class-ph], 010502 geochemistry & geophysics, 01 natural sciences, Geology, 021101 geological & geomatics engineering, 0105 earth and related environmental sciences
Abstract

International audience; For decades, Artificial Ground Freezing (AGF) technique has been used for waterproofing and strengthening soils and soft rocks. However, the resulting pore pressure build up may endanger the stability of adjacent structures located inside and outside the frozen area. Consequently, the use of this technique requires the development of numerical tools that not only allow to predict the extent of the frozen zone around the cooling sources, but also to anticipate the ground movements and the site stability problems. On the basis of the Theory of Porous Media, a thermo-hydro-mechanical coupled model is derived and validated against field data collected in the Cigar Lake underground mine, comprising temperature and tunnel displacement measurements. Three-dimensional finite-element simulations of the Cigar Lake mine have allowed a better understanding of the freezing process and its impacts, in a challenging mining environment.

Published
2019
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17. [An unusual cause of hypertension]

Author

S, El Aoud, H, Tounsi, B, Ben Ammou, E, Chelbi, I, Chaabène, I, Ben Ahmed, R, Amri, W, Garbouj, and K, Bouzaidi

Subjects
Adult, Fatal Outcome, Hypertension, Adrenocortical Carcinoma, Humans, Female, Neoplasm Metastasis, Tomography, X-Ray Computed, Adrenal Cortex Neoplasms
Abstract

Secondary hypertension is relatively rare. Its etiologies are essentially renal or endocrine. The adrenocortical carcinoma, a rare malignant tumor, is one of the most exceptional causes of hypertension. We report the case of a young woman presenting with hypertension and ascites of great abundance. She had hypokalemia, hepatic cytolysis and cholestasis. Thoracic, abdominal and pelvic CT scans showed adrenal mass, liver and lung nodules, osteolytic lesions of the sacrum. The biopsy of liver nodules confirmed the diagnosis of a metastatic malignant adrenocortical carcinoma. The hormonal investigations revealed cortisol and testosterone hypersecretion. The evolution was quickly fatal, the patient passed out a few days after her hospitalization.

Published
2018

18. Modeling heat and mass transfer during ground freezing taking into account the salinity of the saturating fluid

Author

Ahmed Rouabhi, H. Tounsi, Emad Jahangir, Centre de Géosciences (GEOSCIENCES), MINES ParisTech - École nationale supérieure des mines de Paris, and Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)

Subjects
Fluid Flow and Transfer Processes, Ground freezing, 010504 meteorology & atmospheric sciences, Field (physics), Mechanical Engineering, 0211 other engineering and technologies, Numerical modeling, Context (language use), 02 engineering and technology, Mechanics, Condensed Matter Physics, 01 natural sciences, Salinity, Phase change, Fully coupled, [SPI.GCIV]Engineering Sciences [physics]/Civil Engineering, Mass transfer, Environmental science, ComputingMilieux_MISCELLANEOUS, 021101 geological & geomatics engineering, 0105 earth and related environmental sciences
Abstract

In geotechnical engineering applications, the modeling of artificial ground freezing is primarily aimed at predicting the extent of frozen zone around the cooling sources. This modeling could be more or less complex not only according to the material’s texture and the hydro-geological context but also to the salt concentration of the saturating fluid. Through a thermodynamically consistent framework, a fully coupled heat and mass transfer formulation considering the salinity effect was derived. This formulation was intended to capture the most relevant phenomena of ground freezing encountered in geotechnical applications. Particular attention was given to the phase change problem where appropriate simplifying assumptions were made in order to make the proposed methodology easier to apply in field applications. The proposed approach was validated by means of freezing-thawing laboratory tests, carried out on specimens initially fully saturated with sodium chloride solutions at various concentrations. Good agreement was obtained between the measured and predicted results.

Published
2018
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19. [Bilateral pulmonary embolism revealing granulomatosis with polyangiitis]

Author

S, El Aoud, H, Tounsi, I, Chaabène, B, Ben Ammou, I, Ben Ahmed, W, Garbouj, K, Bouzeidi, and R, Amri

Subjects
Male, Granulomatosis with Polyangiitis, Humans, Middle Aged, Pulmonary Embolism
Abstract

Granulomatosis with polyangiitis is a systemic small-vessels vasculitis. It is characterized by a granulomatous inflammatory reaction around the arterial wall and is, in most cases, accompanied by the presence of cytoplasmic - type anti-neutrophil cytoplasmic antibodies (ANCA) with anti-proteinase 3 specificity. The predominant clinical presentation is frequent involvement of the upper and lower respiratory tract and the kidneys. This vasculitis is rarely revealed by pulmonary embolism. We report the observation of a 47-year-old male who presented with acute dyspnea. Chest X-ray disclosed an excavated opacity. Pulmonary angioscan revealed bilateral pulmonary embolism. The absence of clinical improvement after anticoagulant therapy with antibiotics and the presence of extra-respiratory signs led to the suspicion of a systemic inflammatory disease. The etiological investigations concluded with the diagnosis of granulomatosis with polyangiitis.

Published
2018

20. A comparison of insulin lispro Mix25™ and human insulin 30/70 in the treatment of type 2 diabetes during Ramadan

Author

L.K. Levitt, M. Schwarzenhofer, H. Tounsi, Zvonko Milicevic, Vinod Mattoo, N. Rais, L.H.C. Liong, James Malone, and A. Ekangaki

Subjects
Blood Glucose, Male, medicine.medical_specialty, Evening, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Type 2 diabetes, Islam, Endocrinology, Internal medicine, Diabetes mellitus, Internal Medicine, Humans, Hypoglycemic Agents, Insulin, Medicine, Insulin lispro, Morning, Cross-Over Studies, Insulin Lispro, business.industry, Blood Glucose Self-Monitoring, digestive, oral, and skin physiology, Fasting, General Medicine, Middle Aged, Postprandial Period, medicine.disease, Crossover study, Postprandial, Diabetes Mellitus, Type 2, Female, business, medicine.drug
Abstract

Objective: To compare insulin lispro Mix25 and human insulin 30/70 with regard to their effect on morning and evening postprandial glucose (PPG) control, and on average daily blood-glucose (BG), in patients with Type 2 diabetes who wish to fast during Ramadan. Method: Insulin lispro Mix25 and human insulin 30/70 were compared in an open-label, multicenter, randomised, crossover study involving 151 patients. Each treatment period had a duration of 14 days during which the patients self-monitored their BG before and 2 h after the main meals on any 3 days within the last 5 days of each treatment period. Results: The 2 h PPG excursion following the main evening meal after sunset was significantly lower with insulin lispro Mix25 (3.4±2.9 mmol/l) compared with human insulin 30/70 (4.0±3.2 mmol/l, P =0.007). The evening pre-meal fasting BG values were also lower with insulin lispro Mix25 (7.1±2.2 mmol/l) versus human insulin 30/70 (7.5±2.6 mmol/l, P =0.034). The average daily BG concentration was 9.5±2.4 mmol/l during treatment with insulin lispro Mix25 versus 10.1±2.5 mmol/l with human insulin 30/70 given in identical doses ( P =0.004). Conclusion: When compared with human insulin 30/70, treatment of insulin-requiring Type 2 patients with insulin lispro Mix25 during Ramadan resulted in better average daily glycaemia, and better BG control before and after the evening meal. Insulin lispro Mix25 should be considered as a therapeutic option during Ramadan.

Published
2003
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21. Psychotherapies for Complex Trauma: A Combination Between EMDR and Mindfulness

Author

H. Tounsi, L. Riou, P. Pacioselli, J. Palazzolo, A. Quaderi, L. Gross, and C. Gouret

Subjects
Mindfulness, Psychotherapist, Cognitive restructuring, media_common.quotation_subject, medicine.medical_treatment, Cognition, Context (language use), Single-subject design, Desensitization (psychology), Psychiatry and Mental health, medicine, Anxiety, Meditation, medicine.symptom, Psychology, Clinical psychology, media_common
Abstract

Faced with the effects of trauma, new psychotherapies are emerging in France, converging especially around awareness, experience and emotion. The hypothesis put forward here concerns the complementarities of the two following approaches: Mindfulness, part of a behavioural and cognitive context. EMDR that uses neuroscience through its ABS. The implementation of a protocol based on EMDR and mindfulness, has shown convincing results on the demented elderly person suffering from complex PTSD. The protocol begins with a session devoted to anamnesis and symptoms evaluation. The second phase consists of desensitization and cognitive restructuring. The principal foundations rely on EMDR but also include mindfulness exercises to reduce anxiety due to the effects of therapy or otherwise allow the possibility to bring new material when it seems to encounter a deadlock. The third phase is the consolidation of therapeutic benefits. For this, ABS are based on the patient's resources and meditation exercises are performed in order to amplify the restructuration. The combination of these two therapies could allow to potentiate their respective effects. The single case study that we conducted allowed us to observe encouraging results: reduction of symptoms of revival, autonomic hyper-activation and avoidance. Effects were also observed for co-morbid symptoms namely depression, anxiety and psychotic manifestations. The combination of these two approaches seems profitable and requires replication.Disclosure of interestThe authors have not supplied their declaration of competing interest.

Published
2017
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22. Sensitivity to Semantic Cuing: An Index of Episodic Memory Dysfunction in Early Alzheimer Disease

Author

Anne-Marie Ergis, B. Pillon, Bruno Dubois, A Michon, Bernard Deweer, M. Van Der Linden, and H Tounsi

Subjects
Male, medicine.medical_specialty, Audiology, Severity of Illness Index, Developmental psychology, Degenerative disease, Alzheimer Disease, Memory, medicine, Humans, Semantic memory, Dementia, Episodic memory, Aged, Recognition memory, Cognition, Middle Aged, medicine.disease, Semantics, Psychiatry and Mental health, Clinical Psychology, Free recall, Disease Progression, Female, Amnesia, Geriatrics and Gerontology, Alzheimer's disease, Psychology, Gerontology
Abstract

Alzheimer disease (AD) is characterized by episodic memory impairment. This study was aimed at assessing various aspects of episodic memory, and particularly sensitivity to semantic cuing, in patients with various degrees of cognitive deterioration, compared with normal elderly subjects. One hundred thirty-one patients, subdivided into four subgroups as a function of their Mini-Mental State Examination score, were included. All subjects, including 20 normal elderly subject, were given an episodic memory test with controlled encoding and selective reminding. The subgroups of patients were homogeneous in terms of free recall and recognition, but differed in terms of responsiveness to cuing by semantic categories corresponding to the to-be-remembered items. The data confirmed that a severe amnesic syndrome occurs very early in AD, even in a subgroup of patients who did not meet the criteria for dementia. The data indicated that free recall performance, characterized in all subgroups by a floor effect, is not likely to be an appropriate index in pharmacological trials. By contrast, sensitivity to semantic cuing seemed relatively preserved in the early stages, and decreased with the progression of the disease. This index would be the most sensitive index of episodic memory in AD.

Published
1999
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23. Rupture d’anévrysme chez une femme hémodialysée révélatrice d’une maladie de Takayasu

Author

R. Jazi, F. Ben Dahmen, Raja Amri, Y. Ammar, H. Sahli, H. Tounsi, and I. Ben Ahmed

Subjects
Gastroenterology, Internal Medicine
Abstract

Introduction Dans le cadre de la pathologie arterielle inflammatoire, l’arterite de Takayasu occupe une place de choix en raison de sa survenue elective chez des sujets jeunes, de la difficulte de son diagnostic et de la gravite de son evolution. Nous rapportons l’observation d’un anevrysme rompu revelant une maladie de Takayasu chez une jeune femme suivie pour insuffisance renale chronique (IRC) d’etiologie indeterminee. Observation Patiente âgee de 32 ans aux antecedents de mere hemodialysee, admise pour une insuffisance renale avancee de primo decouverte. La patiente a ete hemodialysee en urgence. Au terme du bilan etiologique de son insuffisance renale (hemogramme, bilan infectieux, bilan phosphocalcique, profil tensionnel, UCR, enquete genetique, echographie renale), le diagnostic retenu etait une nephropathie interstitielle chronique d’etiologie indeterminee ; devant les signes de chronicite biologiques et echographiques et surtout l’asymetrie des reins et l’aspect bossele des contours. Dix-huit mois plus tard, la patiente a presente une rupture d’anevrysme de l’aorte abdominale sous-renale pour laquelle, elle a ete operee en urgence avec une reprise pour faux anevrysme anastomotique proximal. L’examen anatomo-pathologique de l’aorte a conclu a une arterite granulomateuse pouvant cadrer avec une maladie de Takayasu. Le bilan lesionnel a objective une importante infiltration de la graisse peri-aortique et mesenterique et une artere iliaque interne gauche anevrysmale, sans anomalie de la graisse autour. Un traitement de fond a base de corticotherapie a forte dose a ete donc instaure, apres une enquete infectieuse negative, avec une degression tres progressive. Et l’insuffisance renale a ete etiquetee de type vasculaire en rapport avec une arterite de Takayasu. Discussion La maladie de Takayasu est une arteriopathie inflammatoire granulomateuse a cellules geantes dont la pathogenie est inconnue. Elle touche les arteres de gros calibre du sujet jeune et son incidence est variable. Les lesions anevrismales sont decrites dans 11 a 27 % des cas, touchant plus souvent l’aorte que ses branches, mais elles sont rarement revelatrices de la maladie. Le diagnostic rapide de cette complication arterielle est indispensable car le pronostic vital a court terme peut etre engage. Notre cas d’anevrysme rompu de l’aorte abdominale sous-renale revelant une maladie de Takayasu est rarement rapporte dans la litterature selon notre connaissance. Les indications du traitement chirurgical sont surtout reservees aux remplacements aortiques, aux lesions anevrismales, a l’insuffisance valvulaire aortique majeure, aux stenoses serrees des arteres renales et pulmonaires et aux echecs de l’angioplastie. Un succes therapeutique est obtenu a long terme dans 80 a 90 % des cas. Mais plusieurs auteurs insistent egalement sur l’interet d’une corticotherapie prealable a la chirurgie. Une prise en charge simultanee chirurgicale et medicale a bien evoluee avec un recul de 7 ans. L’atteinte renale au cours de la maladie de Takayasu est frequente et aggrave le cours evolutif de la maladie. Elle constitue une cause majeur de mortalite et de morbidite. Il s’agit principalement d’une stenose de l’artere renale occasionnant une hypertension arterielle renovasculaire. L’hypertension arterielle est severe dans 70 % des cas et revele la maladie de Takayasu dans 45 % des cas dans la litterature. L’insuffisance renale est plus rare (pres de 30 % des cas au moment de la decouverte de la maladie), souvent c’est une IRC modeste, et secondaire essentiellement a une nephropathie vasculaire. Dans 9 % des cas, elle est d’emblee terminale necessitant l’epuration extrarenale. Le diagnostic de maladie de Takayasu est tardif de plusieurs annees par rapport a l’atteinte renale, comme dans notre cas. Il faut donc y penser toujours devant toute IRC de cause indeterminee chez une sujet jeune. Conclusion L’insuffisance renale terminale et la rupture d’anevrysme de l’aorte sont des complications rares de la maladie de Takayasu et surtout comme tableau inaugural de cette vascularite, ce qui fait la double originalite de notre observation.

Published
2015
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24. Fourth meeting of the European Neurological Society 25–29 June 1994 Barcelona, Spain

Author

H. Hattig, C. Delli Pizzi, M. C. Addonizio, Michelle Davis, A. R. Giovagnoli, L. Florensa, M. Roth, J. de Kruijk, Francisco Lacruz, Ph. Dewailly, A. Toygar, C. Avendano, P.P. De Deyn, J. F. Hurtevent, F. Lomeila, T. W. Wong, Gordon T. Plant, M. Bud, H. J. Willison, DH Miller, D. W. Langdon, R. Cioni, J. Servan, A. Kaygisiz, E. Racadot, D. B. Schens, E. Picciola, L. Falip, C. Bouchard, J. Jotova, A. Jorge-Santamaria, P. Misra, A. Dufour, C. P. Panagopoulos, A. Venneri, B. Sredni, B. Angelard, M. Janelidze, M. Carreno, J. Obenberger, J. Pouget, H. W. Moser, R. Kaufmann, J. A. Molina, D. Linden, A. Martin Urda, E. Uvestad, A. Krone, J. P. Cochin, J. Mallecourt, A. Cambon-Thomsen, K. Violleau, P. Osschmann, A. M. Durocher, E. Bussaglia, D. M. Danielle, H. Efendi, C. Van Broeckhoven, K. G. Jordan, W. Rautenberg, C. Iniguez, J. M. Delgado, Graham Watson, M. Lawden, Gareth J. Barker, K. Stiasny, James T. Becker, G. Campanella, E. Peghi, A. Poli, A. Haddad, T. Yamawaki, Giacomo P. Comi, S. Sotgiu, B. Ersmark, A. Pomes, M. Ziegler, P. Ferrante, P. Ruppi, H. KuÇukoglu, R. Bouton, U. K. Rinne, P. Vieregge, M. Dary, P. Giunti, Peter J. Goadsby, S. Jung, E. Secor, A. Steinberg, N. Vila, M. A. Hernandez, M. Cursi, A. Enqelhardt, A. Engelhardt, J. Veitch, F. Di Silverio, F. Arnaud, B. Neundörfer, R. Brucher, Dominique Caparros-Lefebvre, B. Meyer, Marianne Dieterich, M. H. Snidaro, R. Gomez, R. Cerbo, M. Ragno, J. M. Vance, S. Nemni, A. Caliskan, F. Barros, I. Velcheva, D. Ceballos-Baumann, V. Barak, A. Avila, N. Antonova, F. Resche, S. Pappata, L. Varela, S. R. Silveira Santos, A. Cammarota, L. Naccache, Y. Nara, E. Tournier-Lasserves, R. Mobner, T. Chase, A. Ensenyat, J. Ulrich, G. Giegerich, M. Rother, M. Revilla, N. Nitschke, K. Honczarenko, E. Basart Tarrats, J. Blin, B. Jacob, J. Santamaria, S. Knezevic, J. L. Castillo, M. Antem, J. Colomer, O. Busse, Didier Hannequin, S. Carrier, J. B. Ruidavets, C. Rozman, J. Bogoussslavsky, J. Pascual Calvet, E. Monros, J. M. Polo, M. Zucconl, Javier Muruzabal, R. R. Allen, R. Rivolta, K. Haugaard, A. Nespolo, K. Hoang-Xuang, G. Bussone, T. Avramidis, E. Corsini, Christiana Franke, T. Vinogradova, H. Boot, K. Vestergaard, G. H. Jansen, N. Argentino, M. Raltzig, W. Linssen, Mark B. Pepys, P. Roblot, L. Lauritzen, E. Fainardi, D. Morin, T. X. Arbizu Urdiain, J. Wollenhaupt, S. Bostantjopoulou, G. Pavesi, A. D. Forman, Giovanni Fabbrini, D. Jean, J. J. Archelos, M. I. Blanchs, M. Del Gobbo, Anna Carla Turconi, Ch. Derouesné, Elio Scarpini, A. Visbeck, P. Castejon, J. P. Renou, F. Mounier-Vehier, G. Potagas, Ch. Duyckaerts, A. Filla, R. Schneider, G. Ronen, K. Nagata, J. P. Vedel, A. Henneberg, G. van Melle, C. Baratti, H. Knott, M. C. Prevett, A. Bes, B. Metin, Jos V. Reempts, L. Martorell, Mefkure Eraksoy, H. O. Handwerker, D. S. Younger, O. Oktem, D. Frongillo, C. Soriano-Soriano, L. Niehaus, F. Zipp, A. Tartaro, S Newman, R. H. Browne, P. Davous, R. Sanchez, M. Muros, M. E. Kornhuber, A. Lavarone, M. Mohr, M. R. Garcia, S. Russell, H. Kellar-Wood, M. R. Tola, B. Ostermeyer, Ch. Tzekov, K. Sartor, E. B. Ringelstein, P. P. Gazzaniga, Paul Krack, H. Fidaner, H. Rico, T. Dbaiss, F. Alameda, E. Torchiana, L. Rumbach, I. Charques, J. M. Bogaard, C. D. Frith, L. J. Rappelle, R. Brenner, A. Joutel, K. Fuxe, G. HÄcker, M. J. Blaser, J. Valls-SolÇ, G. Ulm, M. Alberdi, A. Bock, F. W. Bertelsmann, U. Wieshmann, J. Visa, J. R. Lupski, D. D'Amico, L. M. P. Ramos, A. A. Vanderbark, R. Horn, M. Warmuth, Dietmar Kühne, Mark S. Palmer, C. Ehrenheim, E. Canga, S. Viola, O. Scarpino, P. Naldi, R. Almeida, A. A. Raymond, J. Gamez, Stephan Arnold, A. DiGiovanni, J. Dalmau, C. C. Chari, H. F. Beer, J. C. Koetsier, J. Iriarte, E. Yunis, J. Casadevall, E. Le Guern, E. Stenager, S. R. Benbadis, J. M. Warter, F. Burklin, I. Theodorou, L. Johannesen, G. A. Graveland, X. Leclerc, I. Vecchio, L. Ozelius, G. Nicoletti, R. K. Gherardi, E. Esperet, M. L. Delodovici, F. Cattin, F. Paiau, Giorgio Sacilotto, C. A. J. Broere, D. Chavdarov, J. P. Willmer, C. H. Hawkes, Th. Naegele, E. Ellie, E. Dartigues, M. J. Guardiola, S. Hesse, Z. Levic, Marco Rovaris, P. Saugeir-Veber, B. A. Yaqub, H. F. Durwen, R. Larumbe, J. Ballabrina, M. Sendtner, J. Röther, M. Horstink, C. Kluglein, M.P. Montesi, H. Apaydin, J. Montoya, E. Waubant, Ch. Verellen-Dunoulin, A. Nicolai, J. Lopez-Delval, R. Lemon, G. Cantinho, E. Granieri, A. Zeviani, Wolfgang H. Oertel, U. Ficola, V. Di Piero, V. Fragola, K. Sabev, M. V. Guitera, I. Turki, F. Bolgert, P. Ingrand, J. M. Gobernado, L. M. E. Grimaldi, S. Baybas, B. Eymard, Y. Rolland, Y. Robitaille, Ta. Pampols, P. J. Koehler, A. Carroacedo, J. Vilchez, S. Di Vittorio, I. R. Rise, T. Nagy, M. Kuffner, E. Palazzini, A. Ott, J. Pruim, T. X. Arbizu, E. Manetti, C. Cervera, S. Felber, G. Gursoy, J. Scholz, G. A. Buscaino, M. S. Chen, A. Pascual, J. Hazan, J. U. Gajda, J. G. Cea, G. Bottini, G. Damalik, F. Le Doze, G. Bonaldi, J. M. Hew, C. Messina, A. M. Kennedy, J. M. Carney, N. M. F. Murray, M. Parent, M. Koepp, V. Dimova, D. De Leo, K. Jellinger, G. Salemi, S. Mientus, M. L. Hansen, F. Mazzucchelli, J. Vieth, M. Mauri, E. Bartels, L. Johannsen, C. Humphreys, J. Emile, D. N. Landon, E. Kansu, R. Sanchez-Pernaute, Rsj Frackowiak, M. Gonzalez Torres, L. Oller, C. Machedo, J. Kother, M. Billiard, H. Durak, T. Schindler, A. Frank, A. Uncini, A. Sbriccoli, C. Farinas, D. W. Paty, N. Fast, A. T. Zangaladze, A. Kerkhofs, J. M. Pino Garcia, I. De la Fuente, B. Marini, L. Gomez, I. Rubio, Alessandra Bardoni, C. Brodie, P. Acin, U. Sliwka, S. A. Hawkins, S. Tardieu, F. Vitullo, J. M. Pereira Monteino, R. Gagliardi, T. Jezewski, A. Cano, T. Lempert, F. Abad Alegria, G. Rotondo, D. Ince, C. Martinez Parra, Y. Huang, H. Luders, Y. Steinvil, F. G. A. Van Der Meche, R. Bianchi, A. Sanchez, T. Sevilla, J. M. Ketelslegers, A. Domzal-Stryga, M. Pandolfo, M. O. Josse, K. W. Neff, I. Blanco, G. W. Bruyn, O. W. Witte, J. L. Thibault, G. Andersen, J. Pariset, A. Marcone, R. J. M. Lane, A. Hofman, M. Verin, T. Matilla, P. Bedoucha, J. Roche, M. Lai, M. Collard, A. Ugarte, F. Gallecho, D. Silbersweig, C. Kennard, J. P. Azulay, T. W. Ho, P. L. I. Dellemijn, R. Girardello, F. Baas, B. Voss, F. Rozenberg, E. M. Brocker, V. Stanev, A. A. J. Soeterboek, A. Marra, A. Rey, E. Ertem, M. Sawradewicz-Rybak, J. De Keyser, P. Cavallari, F. Proust, Y. Chevalier, H. C. Hansen, D. Leys, C. A. Davie, K. Hoang-Xuan, C. Bairati, H. van Crevel, Thomas T. Warner, B. Bompais, A. Dobbeleir, T Campbell, C. Macko, C. J. M. Klijn, M. Dussallant, T. P. Berlit, W. Rozenbaum, M. J. van den Bent, W. A. Rocca, M. Muller, H. Hundemer, U. Zifko, M. Campera, F. Drislane, D. Ranoux, T. M. Kloss, Anil Kumar, I. Ruolt, C. Bargnani, B. Marescau, N. A. Losseff, S. Notermans, B. Kint, E. T. Burke, C. Aykut, J. Matias Guiu, P. Maquet, T. Drogendijk, M. Leone, K. von Ammon, M. Pepeliarska, C. Prados, L. DiGiamberardino, T. Logtenberg, G. Lenoir, I. Castaldo, Damhaut, M. Radionova, G. Sirabian, R. Navon, Giovanni Antonini, K. Al Moutaery, E. Chamas, R. Schönhuber, M. Giannini, B. Debilly, I. Labatut, H. Henon, J. A. Egido, M. Baudrimont, J. N. Lorenzo, J. E. C. Bromberg, R. Antonacci, J. J. Vilchez, T. Moulin, B. Rautenstrauss, Giovanni Meola, J. Noth, S Mammi, P. Laforet, F. Lopez, C. Gehring, S. Bort, G. Rancurel, D. Decamps, S. Kostadinova, Y. Shapira, B. Neundoerfer, D. Chavrot, M. Solimena, J. P. Salier, W. Deberdt, R. Hoff-Jörgensen, A. Messina, S. Meairs, G. Rosoklija, E. Nelis, I. Bertran, C. Ertekin, J. Lohmeyer, Mitermayer Galvao dos Reis, L. Calo, E. Maccagnano, A. P. Hays, J. Verlooy, M. G. Forno, T. Blanco, L. Bail, Gabriella Silvestri, J. Montero, F. Bertrand, R. T. Ghnassia, C. Besses, T. Sereghy, F. Shalit, G. Bogliun, S. Braghi, St. Baykouchev, C. Franke, A. Lasa, L. C. Archard, J. Kriebel, S. Shaunak, M. Nocito, Alexander Tsiskaridze, E. Manfredini, T. Seigal, David G. Gadian, M. Barlas, J. D. Degos, C. Seeber, J. Caemert, J. L. Mas, R. B. Pepinsky, M. G. D'Angelo, N. Baumann, S. Yorifuji, H. P. Endtz, M. A. Cassatella, R. A. C. Hughes, V. Golzi, A. Bittencourt, A. Ferreira, M. Sanson, C. Alper, M. Vermeulen, M. A. A. van Walderveen, E. Alexiou, C. H. Lucas, M. Fiorelli, Y. N. Debbink, R. Gil, S. Congia, T. Banerjee, J. M. Bouchard, A. N. Pinto, A. Ceballos-Baumann, G. Grollier, P. I. M. Schmitz, M. D. Catata, N. Lahat, N. S. Rao, P. Papathanasopoulos, J. Valls-Solé, D. Claus, G. Schroter, A. Castro, C. Videbaek, R. Martinez Dreke, A. D. Platts, M. Hermesl, A. C. PeÇanha-Martins, M. Cardoso Silva, P. Masnou, M. J. A. Tanner, Ch. Confavreux, B. Mishu, H. Rasmussen, L. Valenciano, Carlo Pozzilli, S. W. Li, V. Salzman, Y. Vashtang, Massimo Franceschi, M. Severo, G. Deuschl, S. Setien, G. Mariani, A. Protti, J. Castillo, M. J. B. Taphoorn, M. Frontali, I. Milonas, D. Decoq, J. A. Navarro, S. Castellvi-Pel, C. Ertikin, M. Urtasun, Y. Lajat, B. E. Kendall, E. Verdu, B. Gueguen, E. Boisen, R. Couderc, A Danek, JM Stevens, F. Nicoli, L. Feltri, M. L. Vazquez-Andre, J. A. Morgan-Hughes, L. D'Angelo, F. Y. Liew, L. F. Pascual, J. Patrignani Ochoa, Vittorio Martinelli, J. Cophignon, L. Zhang, S. Martin, J. F. Meder, H. C. Buschmann, L. Bertin, J. van Gijn, A. Barreiro, A. Cools, C. Leon, A. Berod, E. A. Anllo, E. Zanette, L. Petrov, R. Barona, B. Gallicchio, P. J. Cozzone, N. Diederich, G. Cancel, L. Schelosky, P. Orizaola, K. Yulug, S. Ozer, Valeria A. Sansone, B. Guiraud-Chaumeil, K. Voigt, P. Labauge, M. Eoli, J. Zhu, J. Aguirre, M. Ferrarini, B. Zyluk, E. Planas, A. Cadilha, C. Tortorella, H. Bismuth, C. E. Counsell, A. Laun, A. Ferlini, Rio J. Montalban, N. Biary, L. Becker, M. Fardeau, M. Poloni, V. M. S. de Bruin, C. Fornada, J. Barros, E. Ganzmann, E. Touze, D. Wallach, J. Peila, H. Fujimura, M. T. Iba-Zizen, G. Macchi, C. Villoslada, R. Gouider, Ph. Rondepierre, P. Grummich, P. Chiodi, C. Conte, M. Michels, P. Annunziata, G. Semana, C. Sommer, J. Vajsar, D. Zekin, J. Kulisevsky, David G. Munoz, B. Jacotot, M. Magoni, A. Luxen, T. Garcia-Silva, S. Di Cesare, Christophe Tzourio, M. Gomori, I. Picomell, L. Santoro, F. Villa, Giovanni Pennisi, T. Ribalta, J. M. Molto, L. Marzorati, P. Loiseau, F. Gemignani, A. Gironell, J. Wissel, A. Prusinski, F. Cailloux, P. Villanueva-Hemandez, P. Cozzone, T. Del Ser, J. Sans-Sabrafen, M. Zappia, P. W. A. Willems, G. Tchernia, D. Gardeur, R. Bauer, F. Palomo, H. Metz, S. Lamoureux, C. Chastang, I. Reinhard, A. Goldfarb, S. Harder, Jordi Río, C. Ozkara, E. Tekinsoy, P. Vontobell, J. De Recondo, M. Rabasa, L. Lacomblez, F. Boon, Dgt Thomas, V. Palma, Renato Mantegazza, A. Dervis, M. Nueckel, B. YalÇinerner, I. Duran, G. Dalla Volta, A. Zubimendi, J. Pinheiro, A. Marbini, Xavier Montalban, H. Wekerle, X. Pereira Monteino, F. Crespo, F. Koskas, N. Battistini, C. Ruiz, H. Offner, J. de Pommery, P. Kanovsky, J. Y. Barnett, J. Pardo, G. Tomei, R. Rene, H. M. Lokhorst, P. Thajeb, H. Bilgin, D. McGehee, R. Fahsold, L. Morgante, Katie Sidle, C. Delwaide, M. N. Diaye, P. H. Rice, A. Creange, C. Sabev, K. Stephan, K. WeilBenborn, G. Magnani, L. Grymonprez, F. Cardellach, M. Kaps, N. G. Meco, F. Vega, V. Bonifati, A. Desomer, M. Baldy-Moulinier, G. Kvale, F. J. Authier, B. Yegen, T. Ho, J. M. Rozet, E. A. Cabanis, L. Bruce, L. Ambrosoli, M. A. Petrella, M. Hernandez, P. Timmings, H. B. van der Worp, F. Mahieux, A. Urbano-Marquez, D. A. Krendel, A. A. Garcia, R. Divari, R. Michalowicz, M. R. Piedmonte, M. Bondavalli, M. Zanca, P. F. Ippel, Onofre Combarros, B. Tavitian, E. Hirsch, I. Anastasopoulos, A. Roses, A. Köhler, P. Vienna, V. Timmerman, P. Sergi, F. Cornelio, A. Di Pasquale, R. Verleger, S. Castellvirel, J. Proano, B. van Moll, F. Rubio, W. Hacke, I. Lavenu, L. Zetta, M. W. Tas, N. Bittmann, M. Bonamini, O. R. Hommes, V. Dousset, N. Afsar, S. Belal, R. R. Myers, J. Goes, Giuseppe Vita, E. Clementi, V. G. Karepov, M. Jueptner, A Vincent, P. Emmrich, Th. Heb, A. Caballo, J. Gallego, T. Mokrusch, C. Perla, L. Gebuhrer, O. Titlbach, Alessandro Prelle, A. Czlonkowska, M. Russo, D. Hadjiev, T. S. Chkhikvishvili, M. Oehlschlager, G. Becker, I. Günther, E. N. Stenager, J. Garcia Agundez, J. Casademont, J. Batlle, S. Podobnik-Sarkanji, C. Alonso-Villaverde, B. Delaguillaume, B. Genc, B. Mazoyer, A. Rodriguez-Al-barino, Ch. Hilger, B. Ferrero, R. Price, W. Grisold, L. Fuhry, D. Oulbani, D. Ewing, A. Petkov, W. Walther, A. Gokyigit, John Newsom-Davis, J. Tayot, D. Seliak, G. Pelliccioni, D. Campagne, K. Kessler, F. Boureau, D. Perani, J. P. N'Guyen, N. Tchalucova, B. A. Antin-Ozerkis, C. Lacroix, B. D. Aronovich, I. H. Jenkins, E. A. dos Reis, M. Hortells, H. M. Meinck, H. Ch. Buschmann, S. C. J. M. Jacobs, T. Wetter, P. Creissard, N. Martinez, J. Weidenfeldl, H. J. Sturenburg, G. Damlacik, V. Gracia, J. C. Turpin, A. Pou-Serradell, J. P. Vincent, T. Gagoshidze, U. Ozkutlu, M. McLeod, K. Siegfried, I. Tchaoussoglou, J. Hildebrand, S. Kowalska, M. C. Picot, G. Galardin, L. Crevits, F. Andreetta, S. Larumbe-Lobalde, G. de la Sierra, J. C. Alvarez-Cermeno, R. J. Seitz, P. L. Oey, L. Ptacek, A. M. J. Paans, A. Wirrwar, A. Schmied, J. Uilchez, H. Tounsi, D. Hipola, V. Avoledo, Y. Hirata, P. Vermersch, T. M. Aisonobe, J. Valls-SoIè, H. Staunton, J. Dichgans, R. Karabudak, I. Dones, G. Porta, E. Janssens, Maria Martinez, J. M. Fernandez-Real, R. Villagra, Y. Yoshino, C. Kabus, K. Schimrigk, I. Girard-Buttaz, F. Piccoli, F. Aichner, P. Zuchegna, S. M. Al Deeb, F. Bono, N. Busquets, A. Jobert, Patrizia Ciscato, M. Martin, L. Polman, S. Darbra, V. Le Cam-Duchez, F. Baldissera, B. Baykan-Kurt, D. Guez, M. Bratoeva, H. Matsui, M. Mila, H. Perron, L. Bjorge, G. Husby, Steven T. DeKosky, D. R. Cornblath, J. M. Gabriel, J. J. Poza, Y. Wu, A. Toscano, R. P. Kleyweg, J. Kuhnen, S. O. Confort-Gouny, A. Barcelo, A. M. Conti, C. Fiol, C. Steichen-Wiehn, J. Rodes, M. Cavenaile, C. Vedeler, M. Drlicek, C. Argentino, M. L. Peris, A. Cervello, A. Z. GinaÏ, S. Yancheva, D. Passingham, S. Aoba, D. L. Lopez, T. Rechlin, K. Sonka, L. Grazzi, V. Folnegovic-Smalc, Maurizio Moggio, S. Rivaud, F. G. I. Jennekens, C. H. Hartard, H. Meierkord, G. Stocklin, M. D. Catala, W. C. McKay, E. Salmon, C. Navarro, I. Pastor, L. Canafoglia, M. De Braekeleer, P. K. Thomas, C. Mocellini, C. Pierre-Jerome, M. C. Dalakas, P. Pollak, M. Levivier, Niall Quinn, G. E. Rivolta, Z. Tunca, H. Zeumer, J. Garcia Tena, St. Guily, P. Gaudray, Johannes Kornhuber, V. Petrunjashev, R. Montesanti, R. J. Abbott, H. Petit, G. Kiteva-Trencevska, F. Carletto, C. Ramo, I. M. Pino, P. Beau, G. F. Mennuni, F. Moschian, F. Meneghini, B. Zdziarska, B. Fontaine, C. Stephens, G. Meco, K. Reiners, G. Badlan, M. Sessa, I. Degaey, S. M. Hassan, C. Albani, F. Caroeller, M. Schroeder, G. Savettieri, A. Novelletto, R. Kurita, P. Oschmann, I. Plaza, M. Oliveres, Simone Spuler, A. Molins, M. Schwab, J. R. Kalden, C. P. Gennaula, Y. Baklan, O. Picard, J. M. Léger, B. Mokri, E. Ghidoni, M. Jacob, D. Deplanque, W. JÄnisch, C. De Andres, P. De Deyn, G. Guomundsson, B. Herron, J. Barado, J. L. Gastaut, Guglielmo Scarlato, F. Poron, Nicola Jones, H. Teisserenc, C. P. Hawkins, A. J. Steck, H. C. Chandler, S. Blanc, J. H. Faiss, Jm. Soler Insa, I. Sarova-Ponchas, M. Malberin, A. Sackmann, G. De Vuono, K. Kaiser-Rub, K. Badhia, E. Szwabowska-Orzeszko, S. Ramm, C. Jodice, G. Franck, J. Marta-Moreno, R. Sciolla, C. Fritz, A. Attaccalite, F. Weber, E. Neuman, M. Cannata, A. Rodriguez, I. Nachainkin, R. Raffaele, T. S. Yu, N. Losseff, E. Fabrizio, C. Khati, M. Keipes, M. P. Ortega, M. Ramos-Alvarez, E. Brambilla, A. Tarasov, K. H. Wollinsky, O. B. Paulson, F. Boller, G. Bozzato, H. Wagnur, R. Canton, D. Testa, E. Kutluaye, M. Calopa, D. Smadja, G. Malatesta, F. Baggi, A. Stracciari, G. Daral, G. Avanzini, J. Perret, J. Arenas, P. Boon, I. Gomes, A. Vortmeyer, P. Cesaro, S. Venz, E. Bernd Ringelstein, N. Milani, D. Laplane, P. Seibel, E. Tournier-Lasserve, Alexis Brice, L. Motti, E. Wascher, R. J. Abbot, F. Miralles, A. Turon, P. De Camilli, G. Luz, G. C. Guazzi, S. Tekin, F. Lesoin, T. Kryst, N. Lannoy, F. Gerstenbrand, S. Ballivet, H. A. M. van Diemen, J. Lopez-ArLandis, P. Bell, A. Silvani, M. A. Garcia, S. Vorstrup, D. Langdon, S. Ueno, B. Sander, V. Ozurk, C. Gurses, P. Berlit, J. M. Martinez-Lage, M. Treacy, S. O. Rodiek, S. Cherninkova, J. Grimaud, P. Marozzi, K. Hasert, S. Goldman, S. H. Ingwersen, A. Taghavy, T. Roig, R. Harper, I. Sarova-Pinchas, Anthony H.V. Schapira, R. Lebtahi, A. Vidaller, B. Stankov, D. Link, J. p. Malin, V. Petrova, Ludwig Kappos, J. L. Ochoa, T. Torbergsen, M. Carpo, M. Donato, Simon Shorvon, J. Mieszkowski, J. Perez-Serra, Raymond Voltz, G. Comi, S. Rafique, A. Perez-Sempere, N. Khalfallah, S. Bailleul, M. Borgers, S. Banfi, S. Mossman, A. Laihinen, G. Filippini, R. A. Grunewald, E. Stern, H. D. Herrmann, A. G. Droogan, P. Xue, A. Grilo, L. La Mantia, J. H. J. Wokke, S. Pizzul, Kie Kian Ang, S. Rapaport, W. Szaplyko, B. Romero, P. Brunet, A. Albanese, C. Davie, V. Crespi, F. Birklein, H. Sharif, L. Jose, D. Auer, N. Heye, Martin N. Rossor, C. E. Henderson, M. J. Koepp, J. Rubio, P. L. Baron, S. Mahal, Juha O. Rinne, J. I. Emparanza, S. E. C. Davies, Frederik Barkhof, M. Riva, R. E. Brenner, B. A. Pope, Lemaire, E. Dupont, D. Ulbricht, G. C. Pastorino, R. Retska, E. Chroni, A. Danielli, V. Malashkhia, T. Canet, J. C. Garcia-Valdecasas, J. Serena, R. A. Pfeiffer, B. Wirk, B. Muzzetto, V. Caruso, M. L. Giros, A. Ming Wang, E. L. E. Guern, F. Bille-Turg, Y. Satoh, C. H. Franke, M. Ait-Kaci-Ahmed, D. Genis, T. Pasierski, D. Riva, M. Panisset, A. Chamorro, P.A. van Doorn, S. Schellong, H. Hamer, F. Durif, P. Krauseneck, Y. Bahou, B. A. Pickut, M. Rijnites, H. Nyland, G. Jager, L. L. Serra, A. Rohl, X. P. Li, O. Arena, Hubert Kwieciński, N. Milpied, M. C. Bourdel, S. Assami, L. Law, J. Moszkowski, J. W. Thorpe, M. Aguennouz, R. Martin, D. Hoffmann, P. Morris, A. Destée, D. J. Charron, U. Senin, A. P. SempereE, M. Dreyfus, A. L. Benabid, M. Gomez, S. Heindle, M. C. Morel-Kopp, M. Hennerici, A. I. Santos, M. Djannelidze, N. Artemis, John Collinge, T. Rundek, M. Y. Voloshin, P. de Castro, Th. Wiethege, D. A. S. Compston, D. Schiffer, A. J. Hughes, D. Jimenez, V. Parlato, A. Papadimitriou, J. M. Gergaud, R. Sterzi, J. Arpa, G. de Pinieux, F. Buggle, P. Gimbergues, H. Ruottinen, R. Marzella, W. Koehler, Y. Yurekli, A. Haase, Z. Privorkin, G. K. Harvey, B. Chave, A. J. Grau, E. M. Stadlan, J. List, C. Zorzi, B.W. van Oosten, P. Derkinderen, B. Casati, J. M. Maloteaux, K. Vahedi, W. L. J. van Putten, J. C. Sabourin, D. Lorenzetti, Plenevaux, J. W. B. Moll, A. Morento Fernandez, M. Lema, M. A. Horsfleld, P. De Jongh, S. Gikova, K. Kutluk, Monique M.B. Breteler, P. Saddier, A. Berbinschi, R. E. Cull, P. Echaniz, H. Kober, C. Minault, V. Kramer, A. L. Edal, S. Passero, T. Eckardt, K. E. Davies, A. Salmaggi, R. Kaiser, A. A. Grasso, Claudio Mariani, G. Egersbach, Hakan Gurvit, O. Dereeper, C. Vital, L. Wrabetz, A. Vecino, M. Aguilar, G. Bielicki, H. Becher, J. Castro, S. Iotti, M. G. Natali-Sora, E. Berta, S. Carlomagno, L. Ayuso-Peralta, P. H. Rondepierre, I. Bonaventura, B. V. Deuren, N. Van Blercom, M. Sciaky, J. Faber, M. Alberoni, M. Nieto, F. Sellal, C. Stelmasiak, M. Takao, J. Bradley, D. Zegers de Beyl, H. Porsche, G. Goi, H. Pongratz, F. Chapon, S. Happe, Robin S. Howard, B. Weder, S. Vlaski-Jekic, J. M. Ferro, R. Nemni, A. Daif, Herbert Budka, W. Van Paesschen, B. Waldecker, F. Carceller, J. Lacau, F. Soga, J. Peres Serra, E. Timmerman, A. M. vd Vliet, J. L. Emparanza, N. Vanacore, A. Pizzuti, N. Marti, A. Davalos, N. Ayraud, U. Zettl, J. Vivancos, Z. Katsarou, H. M. Mehdorn, G. Geraud, M. Merlini, M. Schröter, A. Ebner, M. Lanteri-Minet, R. Soler, G. P. Anzola, S. L. Hauser, L. Cahalon, S. DiDonato, R. Cantello, M. Marchau, J. Gioanni, F. Heidenreich, J. Manuel Martinez Lage, P. Descoins, F. Woimant, J. F. Campo, M. H. Verdier-taillefer, M. S. F. Barkhof, G. J. Kemp, A. O. Ceballos-Baumann, J. Berciano, M. Guidi, Tarek A. Yousry, B. Chandra, A. Rapoport, P. Canhao, A. Spitzer, T. Maeda, J. M. Pereira Monteiro, V. Paquis, Th. Mokrusch, F. J. Arrieta, I. Sangla, F. Canizares-Liebana, Lang Chr, André Delacourte, V. Fetoni, P. Kovachev, D. Kidd, L. Ferini-Strambi, E. Donati, E. Idman, A. Chio, C. Queiros, D. Michaelis, S. Boyacigil, A. Rodrigo, S. M. Yelamos, B. Chassande, P. Louwen, C. Tranchant, E. Ciafalon, A. Lombardo, A. Twijnstra, A. L. Fernandez, H. Kott, A. Cannas, N. Zsurger, T. Zileli, E. Metin, P. C. Bain, G. Fromont, B. Tedesi, A. Liberani, X. Navarro, M. C. Rowbotham, V. Hachinski, F. Cavalcanti, W. Rostene, R. M. Gardiner, F. Gonzalez, B. Köster, E. A. van der Veen, J. P. Lefaucheur, C. Marescaux, D. Boucquey, E. Parati, S. Yamaguchi, A. S. Orb, R. Grant, G. D. P. Smith, P. Goethals, M. Haguenau, G. Georgiev, I. N. van Schaik, Guy A. Rouleau, E. Iceman, G. Fayet, M. G. Kaplitt, C. Baracchini, H. Magnusson, G. Meneghetti, N. Malichard, M. L. Subira, D. Mancia, A. Berenguer, D. Navarrete Palau, H. Franssen, G. Kiziltan, M. P. Lopez, J. Montalt, S. Norby, R. Piedra Crespo, T. L. Rothstein, R. Falip, B. YalÇiner, F. Chedru, I. W. Thorpe, F. W. Heatley, D. S. C. Ochoa, C. Labaune, M. Devoti, O. Lider, Jakob Korf, N. Suzuki, E. A. Maguire, A. Moulignier, J. C. van Swieten, F. Monaco, J. Cartron, A. Steck, B. Uludag, M. Alexandra, H. Reichmann, T. Rossi, L. E. Claveria, A. M. Crouzel, M. A. Mena, J. Gasnault, J. W. Kowalski, S. I. Mellgren, V. Feigin, L. Demisch, J. Montalban, J. Renato, J. Mathieu, N. Goebels, L. Bava, K. Kunre, M. Pulik, S. Di Donato, C. Tzekov, H. Veldman, S. Giménez-Roldan, B. Lechevalier, L. Redondo, B. Pillon, M. Gugenheim, E. Roullet, J. M. Valdueza, C. Gori, H. J. Friedrich, L. de Saint Martin, F. Block, E. Basart, M. Heilmann, B. Becq Giraudon, C. Rodolico, G. Stevanin, Elizabeth K. Warrington, A. T. M. Willemsen, K. Kunze, C. Ben Hamida, M. Alam, J. R. ùther, A. Battistel, G. Della Marca, Richard S. J. Frackowiak, F. Palau, T. Brandt, Chicoutimi, L. Bove, L. Callea, A. Jaspert, T. Klopstock, K. Fassbender, Alan J. Thomas, A. Ferbert, V. Nunes, Douglas Russell, P. Garancini, C. Sanz-Sebastian, O. Santiag, G. Dhaenens, G. Seidel, I. Savic, A. Florea-Strat, M. Rousseaux, N. Catala, E. O'Sullivan, M. J. Manifacier, H. Kurtel, T. Mendel, P. Chariot, M. Salas, D. Brenton, R. Lopez, J. Thorpe, Jimmy D. Bell, E. Hofmann, E. Botia, J. Pacquereau, A. Struppler, C. d'Aniello, D. Conway, A. Garcia-Merino, K. Toyooka, S. Hodgkinson, E. Ciusani, Stefano Bastianello, A. Andrade Filho, M. Zaffaroni, G. Pleiffer, F. Coria, A. Schwartz, D. Baltadjiev, I. Rother, K. Joussen, J. Touchon, K. Kutlul, P. Praamstra, H. Sirin, S. Richard, C. Mariottu, L. Frattola, S. T. Dekesky, G. Wieneke, M. Chatel, O. Godefroy, C. Desnuelle, S. OzckmekÇi, C. H. Zielinski, P. van Deventer, S. Jozwiak, I. Galan, J. M. Grau, V. Vieira, T. A. Treves, S. Ertan, A. Pujol, S. Blecic, E. M. Zanette, F. Ceriani, W. Camu, L. Aquilone, A. Benomar, F. Greco, A. Pascual-Leone Pascual, T. Yanagihara, F. A. Delfino, R. Damels, S. Merkelbach, J. Beltran, A. Barrientos, S. Brugge, B. Hildebrandt-Müller, M. H. Nascimento, M. Rocchi, F. Cervantes, E. Castelli, R. M. Pressler, S. Yeil, A. del Olmo, J. L. Herranz, L. J. Kappelle, Y. Demir, N. Inoue, R. Hershkoviz, A. Luengo, S. Bien, F. Viallet, P. Malaspina, G. De Michele, G. Nolfe, P. Adeleine, T. Liehr, G. Fenelon, H. Masson, Kailash P. Bhatia, W. Haberbosch, S. Mederer, R. S. J. Frackowiak, Tanya Stojkovic, S. Previtali, A. E. Harding, W. Kohler, N. P. Quin, T. R. Marra, J. P. Moisan, A. Melchor, M. L. Viguera, Mary G. Sweeney, G. L. Romani, J. Hezel, R. A. Dierckx, R. Torta, A. Kratzer, T. Pauwels, D. Decoo, Adriana Campi, Neil Kitchen, J. Haas, U. Neubauer, J. J. Merland, A. Yagiz, A. Antonuzzo, A. Zangaladze, J. Parra, Pablo Martinez-Lage, D. J. Brooks, S. Hauser, R. Di Pierri, M. Campero, R. Caldarelli-Stefano, A. M. Colangelo, J. L. Pozo, C. Estol, F. Picard, A. Palmieri, J. Massons, JT Phillips, G. B. Groozman, R. Pentore, L. M. Ossege, C. Bayon, Hans-Peter Hartung, R. Konyalioglu, R. Lampis, D. Ancri, M. Miletta, F. J. Claramonte, W. Retz, F. Hentges, JM Cooper, M. Cordes, M. Limburg, M. Brock, G. R. Coulton, K. Helmke, Rosa Larumbe, A. Ohly, F. Landgraf, A. M. Drewes, Claudia Trenkwalder, M. Keidel, T. Segura, C. Scholz, J. HÄgele, D. Baudoin-Martin, P. Manganelli, J. Valdueza, M. Farinotti, U. Zwiener, M. P. Schiavalla, Y. P. Young, O. Barlas, G. Hertel, E. H. Weiss, M. Eiselt, A. Lossos, M. Bartoli, L. Krolicki, W. Villafana, W. Peterson, Nicoletta Meucci, C. Agbo, R. Luksch, F. Fiacco, G. Ponsot, M. Lopez, Howard L. Weiner, M. D. Alonso, K. Petry, Sanjay M. Sisodiya, P. Giustini, S. Tyrdal, R. Poupon, J. Blanke, P. Oubary, A. A. Kruize, H. Trabucchi, R. R. C. Stewart, H. Grehl, B. M. Kulig, V. Vinhas, D. Spagnoli, B. Mahe, J. Tatay, C. Hess, M. D. Albadalejo, G. Birbamer, M. Alonso, F. Valldeoriola, J. Figols, I. Wirguin, E. Diez Tejedor, C. S. Weiller, L.H. van den Berg, P. Barreiro, L. Pianese, S. Cocozza, R. Kohnen, E. Redolfi, F. Faralli, G. Gosztonyl, A. J. Gur, A. Keyser, V. Fichter-Gagnepain, B. Wildemann, E. Omodeo-Zorini, Gregoire, J. Schopohl, F. Fraschini, G. Wunderlich, B. Jakubowska, F. P. Serra, N. B. Jensen, O. Delattre, C. Leno, A. Dario, P. Grafe, F. Graus, M. C. Vigliani, J. L. Dobato, Philip N. Hawkins, R. Marés, A. Rimola, N. Meussi, G. Aimard, W. Hospers, A. M. Robertson, C. Kaplan, W. Lamadé, Karen E. Morrison, Amadio, E. Kieffer, F. Dromer, P. Bernasconi, M. Repeto, Davide Pareyson, Jeremy Rees, A. Guarneri, P. Odin, P. Bouche, L. Nogueira, J. Munoz, L. Leocani, M. J. Arcusa, R. S. J. Frackowiack, John S. Duncan, D. Karacostas, D. Edwin, I. Costa, M. Menetrey, P. Grieb, A. M. Salvan, S. Cunha, P. Merel, P. Pfeiffer, A. Astier, F. Federico, A. Mrabet, M. G. Buzzi, L. Knudsen, I. F. Pye, L. Falqui, C. R. Hornig, C. E. Shaw, C. Brigel, T. C. Britton, R. Codoceo, T. Pampols, Vincent J. Cunningham, N. Archidiacono, G. Chazot, J. B. Posner, L. L. O. Befalo, M. Monclus, C. Cabezas, H. Moser, H. Stodal, J. Ley-Pozo, L. Brusa, R. Di Mascio, P. Giannini, J. Fernandez, R. Santiago Luis, J. Garcia Tigera, J. Wilmink, P. Pignatelli, M. El Amrani, V. Lucivero, M. Baiget, R. Lodi, P. H. Cabre, L. Grande, A. Korczyn, R. Fahlbusch, C. Milanese, W. Huber, J. Susseve, H. C. Nahser, K. Mondrup, X. O. Breakefield, J. Sarria, T. H. Vogt, A. Alessandri, M. Daffertshofer, I. Nelson, M. L. Monticelli, O. Dammann, G. G. Farnarier, G. Felisari, A. Quattrini, A. Boiardi, P. Mazetti, H. Liu, J. Duarte, M. E. Gaunt, H. Strik, N. Yulug, A. Urman, J. Posner, Aida Suarez Gonzalez, Ma. L. Giros, Z. Matkovic, D. Kompf, A. D. Korczyn, A. Steinbrecher, R. Wenzel, M. C. de Rijk, R. Doronzo, J. Julien, O. Hasegawa, M. Kramer, V. Collado-Scidel, M. Alonso de Lecinana, L. Dell'Arciprete, S. Rapuzzi, S. Bahar, H. Willison, M. T. Ramacci, J.J. Martin, Lopez-Bresnahan, C. Malapani, R. Haaxma, T. Rosenberg, J. Patrignani, R. Vichi, Martin R. Farlow, J. Roquer, L. Krols, M. Pimenta, C. Bucka, U. Klose, M. Roberts, J. Salas-Puig, R. Ghnassia, A. Mercuri, C. Maltempo, I. Tournev, P. Homeyer, D. Caparros-Lefevre, E. P. O. Sullivan, T. Vashadze, Ph. Lyrer, A. Deltoro, H. Kondo, M. Steinling, A. Graham, G. C. Miescher, A. Pace, D. Branca, G. Avello, H. H. Kornhuber, D. Fernandes, H. Friedrich, R. Chorao, H. O. Lüders, R. T. Bax, J. A. Macias, N. Yilmaz, J. Veroust, M. Miller, S. Confort-Gouny, J. L. Sastre, D. Servello, G. Boysen, S. Koeppen, V. Planté-Bordeneuve, H. Albrecht, R. H. M. King, G. Orkodashili, R. Doornbos, H. Toyooka, V. Larrue, M. Sabatelli, K. Williams, M. Stevens, V. Maria, M. Comabella, C. Lammers, R. M. L. Poublon, E. Tizzano, P. Pazzaglia, F. Zoeller, M. B. Delisle, J. P. Goument, J. M. Minderhoud, A. Sghirlanzoni, V. Meininger, M. Al Deeb, C. Bertelt, A. Cagni, A. Algra, F. Morales, K. A. Flugel, M. Maidani, M. Noya, Z. Seidl, U. Roelcke, D. Cannata, E. Katiane EmbiruÇu, E. M. Wicklein, K. Willmes, L. Hanoglu, J. F. Pellissier, Yves Agid, E. Cuadrado, S. Brock, D. Maimone, Z. G. Nadareishvili, E. Matta, S. Hilmi, V. Assuerus, F. Lomena, R. Springer, F. Cabrera-Valdivia, Oscar L. Lopez, M. Casazza, F. Vivancos, Ralf Gold, T. Crawford, B. Moulard, M. Poisson, W. l. McDonald, D. E. Grobbe, Alan Connelly, H. Ozcan, S. Abeta, H. Severo Ochoa, A. C. van Loenen, E. Libson, M. J. Marti, B. George, C. Ferrarese, B. Jacobs, L. Divano, T. Ben-Hur, A. L. Bootsma, V. Martinez, A. Conti, R. P. Maguire, B. Schmidt, D. M. Campos, D. A. Guzman, E. Meary, C. Richart, P. B. Christensen, T. Schroeder, Massimo Zeviani, K. Jensen, R. Aliaga, S. Seitz-Dertinger, J. W. Griffin, C. Fryze, H. Baas, S. Braun, A. M. Porrini, B. Yemez, M. J. Sedano, C. Creisson, A. Del Santo, A. Mainz, R. Kay, S. Livraghi, R. de Waal, D. Macgregor, H. Hefter, R. Garghentino, U. Ruotsalainen, M. Matsumoto, M. G. Beaudry, P. M. Morrison, J. C. Petit, C. Walon, Ph. Chemouilli, F. Henderson, R. Massa, A. Cruz Martinez, U. Liska, F. Hecht, Ernst Holler, V. S. de Bruin, B. B. Sheitman, S. M. Bentzen, C. Bayindir, F. Pallesta, P. E. Roland, J. Parrilla, P. Zunker, L. F. Burchinskaya, G. Mellino, S. Ben Ayed, D. Bonneau, P. Nowacki, M. Goncalves, P. Riederer, N. Mavroudakis, J. Togores, L. Rozewicz, S. Robeck, Y. Perez Gilabert, L. Rampello, A. Rogopoulos, S. Martinez, F. Schildermans, C. Radder, P. B. Hedlund, J. Cambier, M. Aabed, G. D. Jackson, P. Gasparini, P. Santacruz, J. Vandevivere, H. Dural, A. Mantel, W. Dorndorf, N. Ediboglu, A. Lofgren, J. Bogousslavsky, P. Thierauf, L. Goullard, R. Maserati, B. Moering, M. Ryba, J. Serra, G. G. Govan, A. Pascual-Leone, S. Schaeffer, M. R. Rosenfeld, A. P. Correia, K. Ray Chaudhuri, L. Campbell, R. Spreafico, B. Genetet, A. M. Tantot, R. A. G. Hughes, J. A. Vidal, G. Erkol, J. Y. Delattre, B. Yaqub, B. K. Hecht, E. Mayayo, Ph. Scheltens, J. Corral, M. Calaf, L. Henderson, C. Y. Li, U. Bogdahn, R. Sanchez-Roy, M. Navasa, J. Ballabriga, G. Broggi, T. Gudeva, C. Rose, J. Vion-Dury, J. A. Gastaut, J. Pniewski, Nicola J. Robertson, G. Kohncke, M. Billot, S. Gok, E. Castellli, F. Denktas, P. Bazzi, F. Spinelli, I. F. Moseley, C. D. Mardsen, B. Barbiroli, O. M. Koriech, A. Miller, Hiroaki Yoshikawa, F. X. Borruat, J. Zielasek, P. Le Coz, J. Pascual, A. Drouet, L. T. Giron, F. Schondube, R. Midgard, M. Alizadeh, M. Liguori, Lionel Ginsberg, L. Harms, C. Tilgner, G. Tognoni, F. Molteni, Mar Tintoré, M. Psylla, C. Goulon-Goeau, M. V. Aguilar, Massimo Filippi, K. H. Mauritz, Thomas V. Fernandez, C. Basset, S. Rossi, P. Meneses, B. Jandolo, T. Locatelli, D. Shechtcr, C. Magnani, R. Ferri, Bruno Dubois, J. M. Warier, S. Berges, F. Idiman, M. Schabet, R. R. Diehl, P. D'aurelio, M. Musior, Reinhard Hohlfeld, P. Smeyers, M. Olivé, A. Riva, C. A. Broere, N. Egund, S. Franceschetti, V. Bonavita, Nicola Canal, E. Timmermans, M. Ruiz, S. Barrandon, G. Vasilaski, B. Deweer, L. Galiano, S. F. T. M. de Bruijn, L. Masana, A. Goossens, B. Heye, K. Lauer, Heinz Gregor Wieser, Stephen R. Williams, B. Garavaglia, A. P. Sempere, F. Grigoletto, P. Poindron, R. Lopez-Pajares, I. Leite, T. A. McNell, C. Caucheteur, J. M. Giron, A. D. Collins, P. Freger, J. Sanhez Del Rio, D. A. Harn, K. Lindner, S. S. Scherer, G. Serve, M. Juncadella, X. Estivill, R. Binkhorst, M. Anderson, B. Tekinsoy, C. Sagan, T. Anastopoulos, G. Japaridze, S. Guillou, F. Erminio, Jon Sussman, P. G. Oomes, D. S. Rust, S. Mascheroni, O. Berger, M. Peresson, K. V. Toyka, T. W. Polder, M. Huberman, B. Arpaci, H. Ramtami, I. Martinez, Ph. Violon, P. P. Gazzaniga Pozzill, R. Ruda, P. Auzou, J. Parker, S. P. Morrissey, Jiahong Zhu, F. Rotondi, P. Baron, W. Schmid, P. Doneda, M. Spadaro, M. C. Nargeot, I. Banchs, J.S.P. van den Berg, R. Ferrai, M. Robotti, M. Fredj, Pedro M. Rodríguez Cruz, B. Erne, D. G. Piepgras, M. C. Arne-Bes, J. Escudero, C. Goetz, A. R. Naylor, M. Hallett, O. Abramsky, E. Bonifacio, L. E. Larsson, R. Pellikka, P. Valalentino, D. Guidetti, B. Buchwald, C. H. Lücking, D. Gauvreau, F. Pfaff, A. Ben Younes-Chennoufi, R. Kiefer, R. Massot, K. A. Hossmann, L. Werdelin, P. J. Baxter, U. Ziflo, S. Allaria, C. D. Marsden, M. Cabaret, S. P. Mueller, E. Calabrese, R. Colao, S. I. Bekkelund, M. Yilmaz, O. Oktem-Tanor, R. Gine, M. E. Scheulen, J. Beuuer, A. Melo, Z. Gulay, M. D. Have, C. Frith, D. Liberati, J. Gozlan, P. Rondot, Ch. Brunholzl, M. Pocchiari, J. Pena, L. Moiola, C. Salvadori, A. Cabello, T. Catarci, S. Webb, C. Dettmers, N. A. Gregson, Alexandra Durr, F. Iglesias, U. Knorr, L. Ferrini-Strambi, F. Kruggel, P. Allard, A. Coquerel, P. Genet, F. Vinuels, C. Oberwittler, A. Torbicki, P. Leffers, B. Renault, B. Fauser, C. Ciano, G. Uziel, J. M. Gibson, F. Anaya, C. Derouesné, C. N. Anagnostou, M. Kaido, W. Eickhoff, G. Talerico, M. L. Berthier, A. Capdevila, M. Alons, D. Rezek, E. Wondrusch, U. Kauerz, D. Mateo, M. A. Chornet, Holon, N. Pinsard, I. Doganer, E. Paoino, H. Strenge, C. Diaz, J. R. Brasic, W. Heide, I. Santilli, W. M. Korn, D. Selcuki, M. J. Barrett, D. Krieger, T. Leon, T. Houallah, M. Tournilhac, C. Nos, D. Chavot, F. Barbieri, F. J. Jimenez-Jimenez, J. Muruzabal, K. Poeck, A. Sennlaub, L. M. Iriarte, L. G. Lazzarino, C. Sanz, P. A. Fischer, S. D. Shorvon, R. Hoermann, F. Delecluse, M. Krams, O. Corabianu, F. H. Hochberg, Christopher J. Mathias, B. Debachy, C. M. Poser, L. Delodovici, A. Jimenez-Escrig, F. Baruzzi, F. Godenberg, D. Cucinotta, P. J. Garcia Ruiz, K. Maier-Hauff, P. R. Bar, R. Mezt, R. Jochens, S. Karakaneva, C. Roberti, E. Caballero, Joseph E. Parisi, M. Zamboni, T. Lacasa, B. Baklan, J. C. Gautier, J. A. Martinez-Matos, W. Pollmann, G. Thomas, L. Verze, E. Chleide, R. Alvarez Sala, I. Noel, E. Albuisson, O. Kastrup, S. I. Rapoport, H. J. Braune, H. Lörler, M. Le Merrer, A. Biraben, S. Soler, S. J. Taagholt, U. Meyding-Lamadé, K. Bleasdale-Barr, Isabella Moroni, Y. Campos, J. Matias-Guiu, G. Edan, M. G. Bousser, John B. Clark, J. Garcia de Yebenes, N. K. Olsen, P. Hitzenberger, S. Einius, Aj Thompson, Ch. J. Vecht, T. Crepin-Leblond, Klaus L. Leenders, A. Di Muzio, L. Georgieva, René Spiegel, K. Sabey, D. Ménégalli, J. Meulstee, U. Liszka, P. Giral, C. Sunol, J. M. Espadaler, A. D. Crockar, K. Varli, G. Giraud, P. J. Hülser, A. Benazzouz, A. Reggio, M. Salvatore, K. Genc, M. Kushnir, S. Barbieri, J. Ph. Azulay, M. Gianelli, N. Bathien, A. AlMemar, F. Hentati, I. Ragueneau, F. Chiarotti, R. C. F. Smits, A. K. Asbury, F. Lacruz, B. Muller, Alan J. Thompson, Gordon Smith, K. Schmidt, C. Daems Monpeun, Juergen Weber, A. Arboix, G. R. Fink, A. M. Cobo, M. Ait Kaci Ahmed, E. Gencheva, Israel-Biet, G. Schlaug, P. De Jonghe, Philip Scheltens, K. Toyka, P. Gonzalez-Porque, A. Cila, J. M. Fernandez, P. Augustin, J. Siclia, S. Medaglini, D. E. Ziogas, A. Feve, L. Kater, G. J. E. Rinkel, D. Leppert, Rüdiger J. Seitz, S. Ried, C. Turc-Carel, G. Smeyers, F. Godinho, M. Czygan, M. Rijntjes, E. Aversa, M. Frigo, Leif Østergaard, J. L. Munoz Blanco, A. Cruz-Matinez, J. De Reuck, C. Theillet, T. Barroso, V. Oikonen, Florence Lebert, M. Kilinc, C. Cordon-Cardon, G. Stoll, E. Thiery, F. Pulcinelli, J. Solski, M. Schmiegelow, L. J. Polman, P. Fernandez-Calle, C. Wikkelso, M. Ben Hamida, M. Laska, E. Kott, W. Sulkowski, C. Lucas, N. M. Bornstein, D. Schmitz, M. W. Lammers, A. de Louw, R. J. S. Wise, P. A. van Darn, C. Antozzi, P. Villanueva, P. H. E. Hilkens, C. Constantin, W. Ricart, A. Wolf, M. Gamba, P. Maguire, Alessandro Padovani, B. M. Patten, Marie Sarazin, H. Ackermann, L. Durelli, S. Timsit, Sebastian Jander, B. W. Scheithauer, G. Demir, J. P. Neau, P. Barbanti, A. Brand, N. AraÇ, V. Fischer-Gagnepain, R. Marchioli, G. Serratrice, C. Maugard-Louboutin, G. T. Spencer, D. Lücke, G. Mainardi, K. Harmant Van Rijckevorsel, G. B. Creel, R. Manzanares, Francesco Fortunato, A. May, J. Workman, K. Johkura, E. Fernandez, Carlo Colosimo, L. Calliauw, L. Bet, Félix F. Cruz-Sánchez, M. Dhib, H. Meinardi, F. Carrara, J. Kuehnen, C. Peiro, H. Lassmann, K. Skovgaard Olsen, A. McDonald, L. Sciulli, A. Cobo, A. Monticelli, B. Conrad, J. Bagunya, J. Benitez, V. Desnizza, B. Dupont, O. Delrieu, D. Moraes, J. J. Heimans, F. Garcia Rio, M. Matsumto, A. Fernandez, R. Nermni, R. Chalmers, M. J. Marchau, F. Aguado, P. Velupillai, P. J. Martin, P. Tassan, V. Demarin, A. Engelien, T. Gerriets, Comar, J. L. Carrasco, J. P. Pruvo, A. Lopez de Munain, D. Pavitt, J. Alarcon, Chris H. Polman, B. Guldin, N. Yeni, Hartmut Brückmann, N. Wilczak, H. Szwed, R. Causaran, G. Kyriazis, M. E. Westarp, M. Gasparini, N. Pecora, J. M. Roda, E. Lang, V. Scaioli, David R. Fish, D. Caputo, O. Gratzl, R. Mercelis, A. Perretti, G. Steimetz, I. Link, C. Rigoletto, A. Catafau, G. Lucotte, M. Buti, G. Fagiolari, A. Piqueras, C. Godinot, J. C. Meurice, Erodriguez J. Dominigo, F. Lionnet, H. Grzelec, David J. Brooks, P. M. G. Munro, F. X. Weilbach, M. Maiwald, W. Split, B. Widjaja-Cramer, V. Ozturk, J. Colas, E. Brizioli, J. Calleja, L. Publio, M. Desi, R. Soffietti, P. Cortinovis-Tourniaire, E. F. Gonano, G. Cavaletti, S. Uselli, K. Westerlind, H. Betuel, C. O. Dhiver, H. Guggenheim, M. Hamon, R. Fazio, P. Lehikoinen, A. Esser, B. Sadzot, G. Fink, Angelo Antonini, D. Bendahan, V. Di Carlo, G. Galardi, A. F. Boller, M. Aksenova, Del Fiore, V. de la Sayette, H. Chabriat, A. Nicoletti, A. Dilouya, M. L. Harpin, E. Rouillet, J. Stam, A. Wolters, M. R. Delgado, Eduardo Tolosa, G. Said, A. J. Lees, L. Rinaldi, A. Schulze-Bonhage, MA Ron, C. Lefebvre, E. W. Radü, R. Alvarez, M. L. Bots, P. Reganati, S. Palazzi, A. Poggi, N. J. Scolding, V. Sazdovitch, T. Moreau, E. Maes, M. A. Estelies, P. Petkova, Jose-Felix Marti-Masso, G De La Meilleure, N. Mullatti, M. Rodegher, N. C. Notermans, T. A. T. Warner, S. Aktan, J. P. Louboutin, L. Volpe, C. Scheidt, W. Aust, C. M. Wiles, U. Schneider, S. K. Braekken, W. R. Willems, K. Usuku, Peter M. Rothwell, C. Talamon, M. L. Sacchetti, A. Codina, M. H. Marion, A. Santoro, J. Roda, A. Bordoni, D. J. Taylor, S. Ertas, H. H. Emmen, J. Vichez, V. BesanÇon, R. E. Passingham, M. L. Malosio, A. Vérier, M. Bamberg, A. W. Hansen, E. Mostacero, G. Gaudriault, Marie Vidailhet, B. Birebent, K. Strijckmans, F. Giannini, T. Kammer, I. Araujo, J. Nowicki, E. Nikolov, A. Hutzelmann, R. Gherardi, J. Verroust, L. Austoni, A. Scheller, A. Vazquez, S. Matheron, H. Holthausen, J. M. Gerard, M. Bataillard, S. Dethy, V. H. Patterson, V. Ivanez, N. P. Hirsch, F. Ozer, M. Sutter, C. Jacomet, M. Mora, Bruno Colombo, A. Sarropoulos, T. H. Papapetropoulos, M. Schwarz, D. S. Dinner, N. Acarin, B. Iandolo, J. O. Riis, P. R. J. Barnes, F. Taroni, J. Kazenwadel, L. Torre, A. Lugaresi, I. L. Henriques, S. Pauli, S. Alfonso, Pedro Quesada, A. S. T. Planting, J. M. Castilla, Thomas Gasser, M. Van der Linden, A. Alfaro, E. Nobile-Orazio, G. Popova, W. Vaalburg, F. G. A. van der Mech, L. Williams, F. Medina, J. P. Vernant, J. Yaouanq, B. Storch-Hagenlocher, A. Potemkowski, R. Riva, M. H. Mahagne, M. Ozturk, Ve. Drory, N. Konic, C. Jungreis, A. Pou Serradell, J. L. Gauvrit, G. J. Chelune, S. Hermandez, T. Dingus, L. Hewer, Ch. Koch, M. N. Metz-Lutz, G. Parlato, M. Sinaki, Charles Pierrot-Deseilligny, H. C. Diener, J. Broeckx, J. Weill-Fulazza, M. L. Villar, M. Rizzo, O. Ganslandt, C. Duran, N. A. Fletcher, G. Di Giovacchino, Susan T. Iannaccone, C. Kolig, N. Fabre, H. A. Crockard, Rita Bella, M. Tazir, E. Papagiannuli, K. Overgaard, Emma Ciafaloni, I. Lorenzetti, F. Viader, P. A. H. Millac, I. Montiel, L. H. Visser, M. Palomar, P. L. Murgia, H. Pedersen, Rafael Blesa, S. Seddigh, W. O. Renier, I. Lemahieu, H. M. L. Jansen, L. Rosin, J. Galofre, K. Mattos, M. Pondal, G. M. Hadjigeorgiou, D. Francis, L. Cantin, D. Stegeman, M. Rango, A. B. M. F. Karim, S. Schraff, B. Castellotti, I. Iriarte, E. Laborde, T. J. Tjan, R. Mutani, D. Toni, B. Bergaasco, J. G. Young, C. Klotzsch, A. Zincone, X. Ducrocq, M. Uchuya, O. J. Kolar, A. Quattrone, T. Bauermann, Nereo Bresolin, J. Vallée, B. C. Jacobs, A. Campos, Werner Poewe, J. A. Villanueva, A. W. Kornhuber, A. Malafosse, E. Diez-Tejedor, G. Jungreia, M. J. A. Puchner, A. Komiyama, O. Saribas, V. Volpini, L. Geremia, S. Bressi, A. Nibbio, Timothy E. Bates, T. z. Tzonev, E. Ideman, G. A. Damlacik, G. Martino, G. Crepaldi, T. Martino, Kjell Någren, E. Idiman, D. Samuel, J. M. Perez Trullen, Y. van der Graaf, J. O. Thorell, M. J. M. Dupuis, E. Sieber, R. D'Alessandro, C. Cazzaniga, J. Faiss, A. Tanguy, A. Schick, I. Hoksergen, A. Cardozo, R. Shakarishvili, G. K. Wennlng, J. L. Marti-Vilalta, J. Weissenbach, I. L. Simone, Amalia C. Bruni, Darius J. Adams, C. Weiller, A. Pietrangeli, F. Croria, C. Vigo-Pelfrey, Patricia Limousin, A. Ducros, G. Conti, O. Lindvall, E. Richter, M. Zuffi, A. Nappo, T. Riise, J. Wijdenes, M. J. Fernandez, J. Rosell, P. Vermersh, S. Servidei, M. S. C. Verdugo, F. Gouttiere, W. Solbach, M. Malbezin, I. S. Watanabe, A. Tumac, W. I. McDonald, D. A. Butterfield, P. P. Costa, F. deRino, F. Bamonti, J. M. Cesar, C. H. Lahoz, I. Mosely, M. Starck, M. H. Lemaitre, K. M. Stephan, S. Tex, R. Bokonjic, I. Mollee, L. Pastena, M. Gutierrez, F. Boiler, M. C. Martinez-Para, M. Velicogna, O. Obuz, A. Grinspan, M. Guarino, L. M. Cartier, E. Ruiz, D. Gambi, S. Messina, M. Villa, Michael G. Hanna, J. Valk, Leone Pascual, M. Clanet, Z. Argov, B. Ryniewicz, E. Magni, B. Berlanga, K. S. Wong, C. Gellera, C. Prevost, F. Gonzalez-Huix, R. Petraroli, J. E. G. Benedikz, I. Kojder, C. Bommelaer, L. Perusse, M. R. Bangioanni, Guy M. McKhann, A. Molina, C. Fresquet, E. Sindern, Florence Pasquier, M. J. Rosas, M. Altieri, O. Simoncini, M. Koutroumanidis, C. A. F. Tulleken, M. Dary-Auriol, S. Oueslati, H. Kruyer, I. Nishisho, C. R. Horning, A. Vital, G. V. Czettritz, J. Ph. Neau, B. Mihout, A. Ameri, M. Francis, S. Quasthoff, D. Taussig, S. Blunt, P. Valentin, C. Y. Gao, O. Heinzlef, H. d'Allens, C. Coudero, M. Erfas, G. Borghero, P. J. Modrego Pardo, M. C. Patrosso, N. L. Gershfeld, P. A. J. M. Boon, O. Sabouraud, M. Lara, J. Svennevig, G. L. Lenzi, A. Barrio, H. Villaroya, JosÇ M. Manubens, O. Boespflug-Tanguy, M. Carreras, D. A. Costiga, J. P. Breux, S. Lynn, C. Oliveras Ley, A. G. Herbaut, J. Nos, C. Tornali, Y. A. Hekster, J. L. Chopard, J. M. Manubens, P. Chemouilli, A. Jovicic, F. Dworzak, S. Smirne, S. E. Soudain, B. Gallano, D. Lubach, G. Masullo, G. Izquierdo, A. Pascual Leone Pascual, A. Sessa, V. Freitas, O. Crambes, L. Ouss, G. W. Van Dijk, P. Marchettini, P. Confalonieri, M. Donaghy, A. Munnich, M. Corbo, and M. E. L. van der Burg

Subjects
Neurology, business.industry, Media studies, Library science, Medicine, Neurology (clinical), business
Published
1994
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25. A proxy-based framework for QoS-enabled Internet access in VANETS

Author

Mounir Frikha, A. Ksentini, and H. Tounsi

Subjects
Routing protocol, Vehicular ad hoc network, business.product_category, business.industry, Wireless ad hoc network, Computer science, Quality of service, ComputerSystemsOrganization_COMPUTER-COMMUNICATIONNETWORKS, Mobile computing, Wireless lan, Internet access, The Internet, IEEE 802.11p, business, Computer network
Abstract

A Vehicle Ad hoc Network (VANET) is composed of vehicles, with short range wireless communication capabilities. Vehicular networks can support both Vehicle-to-Vehicle and Vehicle-to-Infrastructure communications, and are targeted at the delivery of both road safety applications and non-safety applications, including comfort applications. Comfort applications aim to provide information and entertainment to people on traveling. These applications are typically bandwidth-demanding, have real time delivery requirements, and ask for the network capability to offer continuous access to the Internet together with a controlled Quality of service (QoS). To better cope with the dynamic nature of this network, the IEEE 802.11p has been proposed as a draft amendment to the IEEE 802.11 standard. Its core mechanism is based on the Enhanced Distributed Channel Access (EDCA) for QoS management. VANET-to-Internet access needs the cooperation of certain elements of the network to serve as gateways, to choose the optimal route for them and maintain it, and to ensure users preferences and requirements of QoS. One of the challenges in VANET-to-Internet communication is how to provide connection in areas where no gateways are available. In this paper, we introduce a new QoS framework to ensure data forwarding to Internet in gateway-free area. It consists of a Proxy-based Vehicle to Internet (PVI) protocol, with a Prediction-based Routing (PBR) algorithm and IEEE 802.11p EDCA scheme.

Published
2010
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26. Well-balanced Component-wise Scheme for Shallow Water System

Author

M. Louaked, H. Tounsi, Michail D. Todorov, and Christo I. Christov

Subjects
Mathematical logic, Hydrogen compounds, Chemistry, Wave equation, GeneralLiterature_MISCELLANEOUS, law.invention, Waves and shallow water, Classical mechanics, Robustness (computer science), Control theory, law, Free surface, Wetting, Hydrostatic equilibrium, ComputingMethodologies_COMPUTERGRAPHICS
Abstract

This paper presents a well‐balanced numerical scheme for solving free surface flows involving wetting and drying. The proposed algorithm combines a component‐wise approach with hydrostatic reconstruction strategy to compute flows over wet or dry surfaces and to satisfy the steady state condition of still water. The robustness of the proposed scheme is verified under several benchmark hydraulic tests.

Published
2010
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27. Un abdomen aigu chirurgical révélant une angéite granulomateuse allergique

Author

H. Sahli, Y. Ammar, Raja Amri, I. Ben Ahmed, H. Touinsi, H. Tounsi, F. Ben Dahmen, R. Jazi, and R. Khalfallah

Subjects
Gastroenterology, Internal Medicine
Abstract

Introduction L’angeite granulomateuse allergique (AGA) appelee auparavant syndrome de Churg-Strauss (SCS) est une vascularite systemique, d’etiopathogenie non encore elucidee, definie par son association a un asthme grave et a une hypereosinophilie sanguine et tissulaire. Sa prevalence, de 7 a 13 par million d’habitants, en fait une des vascularites systemiques les plus rares. Observation Patient âge de 38 ans, aux antecedents de nodules sous-cutanes non explores, qui a opere par une cœlioscopie diagnostique pour un syndrome sub-occlusif aigu. L’aspect peroperatoire etait typique d’une vascularite. Par ailleurs, l’etude histologique d’une tumefaction axillaire gauche d’allure lipomateuse a montre la presence autour des vaisseaux de moyen calibre d’un infiltrat inflammatoire a predominance PNN et eosinophiles. Ces derniers dissocient la paroi vasculaire au niveau de la media et l’adventice. L’hemogramme montre une hypereosinophilie. Les anticorps anti-nucleaires, anticorps anti-phospholipides et les anticorps anti-cytoplasme de polynucleaires neutrophiles (ANCA) etaient negatifs. Dans le cadre du bilan lesionnel de la vascularite, la proteinurie de 24 heures etaient negative, la fonction renale etait normale. L’endoscopie digestive haute montrait une œsophagite peptique grade B et une gastroraphie antrale congestive. La colonoscopie ne revelait pas d’anomalies. L’examen ORL etait normal. Les autres investigations : ETT, TDM thoracique et du massif facial, IRM cerebrale et EMG etaient sans particularites. Le diagnostic AGA etait retenu devant une inflammation riche en eosinophile avec vascularite necrosante des petits et moyens vaisseaux associes a une eosinophilie. Le FFS etant egal a 1, le patient a ete traite par des boli de Solumedrol relayes par une corticotherapie orale a dose de 1 mg/kg/j os associes d’emblee a 6 cures mensuelles de cyclophosphamide relayees par l’azathiopirine. L’evolution sous traitement etait spectaculaire avec disparition des douleurs abdominales. Depuis, le patient est reste asymptomatique sous traitement de fond a base de 10 mg/j de corticoides et 100 mg/j d’azathiopirine, avec un recul de 24 mois. Discussion L’atteinte pulmonaire souvent a type d’asthme tardif est le mode de revelation le plus habituel dans l’AGA. Cependant, d’autres atteintes peuvent inaugurer le tableau clinique et risquent de faire meconnaitre le diagnostic en dehors d’une demarche diagnostique rigoureuse. Les manifestations digestives sont rapportees dans 8 a 62 % des cas. Elles peuvent etre au centre du tableau clinique et revelent exceptionnellement la maladie. Les manifestations cutanees se voient dans 40a 70 % des cas a type de purpura vasculaire et d’erytheme noueux, exceptionnellement de tumefactions sous-cutanees. Notre observation est originale du fait du mode de revelation inhabituel de la maladie, et de la localisation cutanee atypique. Conclusion Une atteinte digestive peut reveler une AGA. En presence de ce type d’atteinte, le traitement doit associer une corticotherapie et du cyclophosphamide intraveineux, les atteintes digestives constituant un critere de gravite au cours du syndrome de Churg-Strauss. L’atteinte cutanee revele rarement la maladie, parfois dans des localisations peu frequentes comme la tumefaction sous axillaire dans notre observation.

Published
2015
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28. P-213: A stroke ischemic revelant a Basedow graves disease

Author

H. Tounsi, H. Sehli, N. Riden, B. Ben Ammou, N. Mtaaouä, I. Ben Ahmed, Raja Amri, and R. Jazi

Subjects
Gynecology, medicine.medical_specialty, business.industry, Graves' disease, medicine, Cardiology and Cardiovascular Medicine, medicine.disease, business
Abstract

Objectifs La maladie de basedow est une forme clinique de l'hyperthyroidie qui peut etre revelee par un amaigrissement, une exophtalmie, des diarrhees et des troubles du rythme cardiaque. Methodes Nous rapportons une complication inhabituelle faisant reveler la maladie. Resultats Patient âge de 34 ans sans antecedents pathologiques notables qui consulte aux urgences pour dysarthrie avec hemiparesie droite. Le scanner cerebral a objective une lesion ischemique temporoparietale gauche, l'ECG a montre une ACFA, qui a ete reduite medicalement. Ainsi le diagnostic d'un AVC ischemique secondaire a l'ACFA a ete retenu. Devant le jeune âge, les antecedents familiaux de dysthyroidie et la presence d'un goitre modere a l'examen, un bilan thyroidien a ete demande objectivant une hyperthyroidie franche. Le patient etait mis sous ATS, associe au traitement de l'ACFA, et une reeducation motrice et orthophonique avec une bonne evolution clinique et biologique. Conclusion L'AVC ischemique est une complication inhabituelle de l'hyperthyroidie et en constitue rarement une circonstance de decouverte. Il fauty penser devant le jeune âge, les signes associes notamment les troubles du rythme sur un cœur sain. Un traitement bien conduit de l'hyperthyroidie en plus du traitement symptomatique fait eviter les complications et la recidive des troubles thromboemboliques.

Published
2015
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29. Sarcoïdose systémique révélée par une localisation thyroïdienne : à propos d’un cas

Author

Y. Ammar, M. Mekky, H. Tounsi, H. Sahli, Raja Amri, F. Ben Dahman, and I. Ben Ahmed

Subjects
Endocrinology, Endocrinology, Diabetes and Metabolism, General Medicine
Abstract

Introduction Les atteintes thyroidiennes au cours de la sarcoidose sont decrites, mais rarement confirmees histologiquement. Leur frequence est de 1 % a 4 %. Cependant, elles sont exceptionnellement revelatrices. Observation Patiente âgee de 59 ans, qui etait operee pour un goitre multi-nodulaire avec euthyroidie clinique et biologique. L’etude histologique conclurait a une sarcoidose. Les explorations secondaires montraient une atteinte pulmonaire type II. Une corticotherapie etait instauree. A ce propos, nous discutons les differents aspects cliniques et les difficultes posees par cette particuliere localisation thyroidienne. Discussion La sarcoidose est une maladie granulomateuse d’origine indeterminee. Les atteintes les plus frequentes sont mediastino-pulmnonaires, cutanees, ophtalmologiques et renales. Le diagnostic formel est permis par l’histologique. L’evolution se fait soit vers la guerison, soit vers l’apparition d’une fibrose avec depot de collagene et destruction du tissu sain. L’interet du cas present est l’association de la localisation thyroidienne rare dans la sarcoidose avec une preuve formelle par l’examen anatomopathologique du goitre. Ainsi que le mode de revelation de la maladie qui est le goitre thyroidien. Les etudes autopsiques revelent 1,3 % a 4,2 % de localisations thyroidiennes chez l’adulte atteint de sarcoidose sans notion d’atteinte clinique ou biologique. Cliniquement, la frequence de l’atteinte thyroidienne varie de 0,6 % a 19 % selon les etudes. Il s’agit le plus souvent d’une atteinte purement morphologique : goitre simple ou nodule benin. Les anomalies fonctionnelles sont plus rares : thyroidites, hypothyroidie. La positivite des anticorps quelle que soit la methode utilisee est plus importante chez les patients atteints de sarcoidose.

Published
2015
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30. Le syndrome métabolique chez des diabétiques de type 2 tunisiens récemment diagnostiqués et évaluation de l’épaisseur intima média carotidienne

Author

B. Zouari, I. Ben Ahmed, H. Tounsi, B. Ben Ammou, H. Sahli, Raja Amri, R. Khalfallah, and K. Bouzaidi

Subjects
Endocrinology, Endocrinology, Diabetes and Metabolism, General Medicine
Abstract

Introduction Le risque cardiovasculaire apparait tres tot dans l’histoire du diabete, il est lie a une constellations d’anomalies metaboliques et a un profil atherogene. Objectifs Determiner la frequence du syndrome metabolique et evaluer l’epaisseur intima media carotidienne des diabetiques de type 2 Tunisiens nouvellement diagnostiques et les comparer a un groupe temoin. Patients et methodes Des diabetiques de type 2 recemment diagnostiques et des temoins non diabetiques sont apparies selon l’âge et le sexe dans les consultations externes de diabetologie de l’hopital Mohammed Taher El Maamouri de Nabeul. Le groupe temoin etait recrute parmi le personnel medical et paramedical de l’hopital. Nous avons mesure par echographie de haute resolution l’epaisseur intima media carotidienne (IMT) de la carotide commune et de la bifurcation carotidienne. Resultats L’obesite est plus frequente chez les diabetiques (52,9 %) que chez les temoins (21,8 %). La frequence du syndrome metabolique est 3 fois plus eleve chez les diabetiques (17,7 %) que chez les sujets sains (6,2 %). La pression arterielle systolique et la triglyceridemie sont significativement plus eleves chez les diabetiques que chez les temoins (128 ± 24,1 versus 113,8 ± 11,2 mmHg et 2,15 ± 1,27 versus 1,14 ± 0,57 mmol/L). L’IMT moyenne chez les diabetiques est de 0,66 ± 0,34 mm versus 0,43 ± 0,19 mm chez les temoins (p = 0,005) temoignant d’une atherosclerose precoce meme au tout debut du diagnostic de la maladie. Conclusion Le syndrome metabolique se situe aux frontieres et aux origines du diabete de type 2 et il est responsable d’une atherosclerose severe et precoce avec un risque cardiovasculaire eleve.

Published
2015
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33. Small packets aggregation in an IP domain

Author

Laurent Toutain, H. Tounsi, Farouk Kamoun, Département Réseaux, Sécurité et Multimédia (RSM), and Université européenne de Bretagne - European University of Brittany (UEB)-Télécom Bretagne-Institut Mines-Télécom [Paris] (IMT)

Subjects
Router, FIFO (computing and electronics), Computer science, IP forwarding, Internet traffic engineering, Packet switch, [INFO.INFO-NI]Computer Science [cs]/Networking and Internet Architecture [cs.NI], Packet switching, Network performance, Queue, Traffic generation model, Processing delay, Forwarding equivalence class, ComputingMilieux_MISCELLANEOUS, Queueing theory, Internet, Voice over IP, business.industry, Network packet, ComputerSystemsOrganization_COMPUTER-COMMUNICATIONNETWORKS, [INFO.INFO-MM]Computer Science [cs]/Multimedia [cs.MM], Packet telephony, Packet forwarding, Routing domain, business, Computer network
Abstract

With the emergence of new multimedia applications and the large standardization effort of packet telephony products, a large volume of small packet traffic flows in the network. It is expected to get worse with the popularity of VoIP applications. To mitigate the impact of small packets we propose the aggregation of packets present in the output queue and which have the same forwarding equivalence class, such as those which will leave a routing domain from the same node (an egress node). The set of aggregated packets will be subsequently treated as a single packet, thus requiring smaller processing overhead at intermediate routers. We report the results of several simulations that evaluate the performance benefits of aggregation. We note that aggregation keeps the same behavior as pure FIFO. Thus it doesn't disturb the aggregator router behavior. It saves CPU processing time and buffer space at intermediate routers, thus improving the overall network performance.

Published
2001
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34. [Fronto-temporal dementia: a clinical approach]

Author

Z, Arvanitakis, H, Tounsi, B, Pillon, and B, Dubois

Subjects
Male, Brain Diseases, Humans, Dementia, Female, Atrophy, Middle Aged, Neuropsychological Tests, Cognition Disorders, Magnetic Resonance Imaging, Temporal Lobe, Aged, Frontal Lobe
Abstract

Although the existence of atrophy of the anterior part of the brain has been known for a long time (Pick, 1892), the interest for fronto-temporal dementias (DFT) is relatively recent. Several excellent reviews have been recently published on the topic (Gustafson, 1993; Neary and Snowden, 1996; Pasquier et al., 1998) and, for that reason, we only recall the main aspects of the disease to insist on some lesser known features, illustrated by original observations.

Published
1999

37. THU0483 Arterial Aneurysms in Behcet’s Disease. A Report of 25 Cases

Author

H. Tounsi, M. Khanfir-Smiti, M. Lamloum, M.H. Houman, I. Ben Ghorbel, T. Ben Salem, A. Hamzaoui, and N. Belfeki

Subjects
medicine.medical_specialty, Abdominal pain, business.industry, Immunology, Femoral artery, medicine.disease, Internal iliac artery, General Biochemistry, Genetics and Molecular Biology, Surgery, Venous thrombosis, Posterior tibial artery, Aneurysm, Rheumatology, medicine.artery, cardiovascular system, Deep Femoral Artery, medicine, Immunology and Allergy, cardiovascular diseases, Radiology, Myocardial infarction, medicine.symptom, business
Abstract

Background Arterial involvements occur in less than 10 % of patients with Behcet’s disease (BD). Aneurysms are the most frequent lesions and constitute one of the mortality’s causes. Objectives The aim of this study was to evaluate prevalence of aneurysms in BD in Tunisian patients and to describe clinical features, treatment and outcome of patients having this involvement. Methods A retrospective study was made. Files of patients followed for BD (criteria of the International Study Group of BD) in our internal medicine department were studied. Patients having arterial aneurysms were included. Aneurysm diagnosis was confirmed, according to his location, using cerebral, thoracic or abdominal scanography, coronarography or doppler ultrasound. Results Among 488 patients with BD, 25 had arterial aneurysms (5.1%). There were 23 men and 2 women. The mean age at the disease onset was 29 +/- 10.28 years, and was 33.84 +/- 10.14 years at BD diagnosis. Aneurysm revealed BD in 12 cases (2.4%). Abdominal aorta aneurysm was the most frequent (8 cases). Aneurysms in pulmonary arteries were confirmed in 7 cases and superficial femoral artery was involved in 2 patients. Other locations as primitive carotid artery, humeral artery, hypogastric artery, internal iliac artery, communal femoral artery, deep femoral artery, poplit artery and posterior tibial artery were noted each in only one case. Two patients underwent a myocardial infarction due to coronial artery aneurysm. Two patients had 2 different locations. All patients were symptomatic (abdominal pain, thoracic pain, limbs pain, gastrointestinal bleeding or haemoptysis). Comparison between patients with and without aneurysm showed that ocular involvement and HLA B51 were significantly less frequent in patients having aneurysm whereas deep venous thrombosis were significantly more frequent in these patients. All patients were treated by corticosteroids, 10 patients had surgery associated to immunosuppressive therapy (8 patients). The other patients had only immunosuppressive therapy. Only 2 patients had relapse. One patient died because of aneurysm rupture before any treatment. Conclusions Arterial aneurysms are uncommon in BD. They were significantly associated to deep venous thrombosis. Aneurysms still being a serious complication in patients with BD, but treated early, the outcome is good. Disclosure of Interest None Declared

Published
2013
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38. AB0386 Sjögren’s syndrome associated with mpo-anca-positive polyangiitis

Author

A. Mersni, A. Hamzaoui, T. Ben Salem, H. Tounsi, M. Smiti, I. Ben Ghorbel, M.H. Houman, and M. Lamloum

Subjects
Autoimmune disease, Pathology, medicine.medical_specialty, medicine.diagnostic_test, Cyclophosphamide, business.industry, Immunology, Autoantibody, Glomerulonephritis, medicine.disease, Dermatology, General Biochemistry, Genetics and Molecular Biology, stomatognathic diseases, Rheumatology, Skin biopsy, medicine, Immunology and Allergy, Renal biopsy, Microscopic polyangiitis, Vasculitis, business, medicine.drug
Abstract

Background Sjogren’s syndrome (SS) is a chronic autoimmune disease that is commonly manifested by immune attack on the exocrine glands with resultant dry eyes and dry mouth. Sjogren’s syndrome patients also have disease in other organs. Objectives To study the cases of SS associated with MPO-ANCA-positive polyangiitis. Results We report 4 cases (were female) with Sjogren syndrome developed microscopic polyangiitis. The accurate diagnosis of SS was established based on objective signs and symptoms of ocular and oral dryness and characteristic appearance of a biopsy sample from a minor salivary gland, and presence of anti-SS-A autoantibody. The patient also tested positive for myeloperoxidase-antineutrophil cytoplasmic antibodies (MPO-ANCA), with changes in the MPO-ANCA titer that paralleled changes in the symptoms. Histologic finding of skin biopsy of purpuric lesion was typical for leukocytoclastic vasculitis. Renal biopsy was performed for nephrotic range proteinuria. The pathologic finding of renal biopsy was necrotizing crescentic membranous glomerulonephritis. The patients were treated with oral glucocorticoids in combination with cyclophosphamide and with local symptomatic therapy for ocular and oral dryness. Renal function stabilized after 2 months, and tests for anti-myeloperoxidase reverted to negative. Conclusions SS is one of the most common autoimmune disorders and vasculitis is one of the most characteristic extraglandular manifestations, but wide spectrum of cutaneous involvement in SS has been little studied. Disclosure of Interest None Declared

Published
2013
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39. Évaluation du risque cardiovasculaire au cours du lupus érythémateux systémique : à propos de 52 patients

Author

H. Tounsi, Y. Kort, A. Hamzaoui, M. Lamloum, M. Smiti Khanfir, M.H. Houman, T. Ben Salem, and I. Ben Ghorbel

Subjects
Gastroenterology, Internal Medicine
Abstract

vee chez 15patients (23%) avec une predominance de l’atteinte pericardique notee chez 11patients, soit 73%. La pericardite etait isolee dans cinq cas, associee a une atteinte endocardique dans quatre cas et a une atteinte myocardique chez un deux patients. Tous nos patients lupique avec pericardite etaient asymptomatiques et le diagnostic a ete fait grâce a l’echographie cardiaque faite dans le cadre du bilan de retentissement du LES. L’evolution etait favorable, avec regression rapide sous traitement anti-inflammatoire non steroidien ou corticotherapie dans 90%. Conclusion.– L’atteinte cardiaque au cours du LES demeure dominee par la pericardite. Les atteintes cardiaques et notamment la localisation pericardique sont plus frequentes que ne le suggere la clinique. L’echocardiographie apparait alors comme un outil diagnostique pratique devant etre systematiquement realise. Sa place est incontestable dans l’evaluation initiale de la maladie et de son profil evolutif sous traitement.

Published
2013
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40. [Spinal cord compression in bone fluorosis. Apropos of 4 cases]

Author

A, Mrabet, M, Fredj, S, Ben Ammou, H, Tounsi, and A, Haddad

Subjects
Male, Spinal Osteophytosis, Ossification, Heterotopic, Chronic Disease, Cervical Vertebrae, Humans, Female, Bone Diseases, Middle Aged, Spinal Cord Compression, Fluoride Poisoning
Abstract

The authors report four cases of spinal cord compression (three at cervical level and one at dorsal level) due to vertebral osteosclerosis secondary to chronic fluoride intoxication. Roentgenograms showed typical diffuse densification of vertebral bodies, calcifications of bony insertions of many ligaments, discs and interosseous membranes. Urinary fluoride was markedly increased in two cases. In the other two cases the bone biopsy was suggestive of skeletal fluorosis. Spinal computed tomography showed severe cord compression due to posterior osteophytes. Good improvement was observed after surgical decompression in one case. Fluorosis was described as a consequence of endemic exposure to high fluoride content in soil and natural ground water in North Africa. Fluorotic myelopathy was due to bone excrescences mainly affecting the spine.

Published
1995

44. [Tormented old age. A case report]

Author

Z, Hachemi, Z, Abroug, and H, Tounsi

Subjects
Diagnosis, Differential, Male, Radiography, Depressive Disorder, Hematoma, Subdural, Guilt, Humans, Confusion, Aged
Published
1994

48. Symptomatic hypercalcemia and lytic lesions of the skull revealing sarcoidosis: A case report.

Author

Tounsi H, Skouri W, Jlidi M, Bachrouch S, Mami H, Kaabar Y, Sbaihi S, Chaabane A, Amri R, and Alaya Z

Abstract

Sarcoidosis is a systemic granulomatosis of unknown etiology. Mediastinal lymph node and pulmonary involvement are the most characteristic manifestations. However, bone involvement is rare during sarcoidosis. Herein, we describe an atypical case of sarcoidosis revealed by a severe hypercalcemia and lytic lesions of the skull without pulmonary or mediastinal manifestation. A 53-year-old woman was admitted for symptomatic hypercalcemia of 3.8 mmoL/L. The initial good course after hydration combined with a dose of intravenous zoledronate was followed by a relapse of hypercalcemia. Computed tomography (CT) scan showed 2 lytic lesions of the skull and multiple nodules and micronodules in the liver and the spleen which were of normal size. The histological examination showed a non-necrotizing granulomatous hepatitis, with no signs of malignancy. The bone marrow biopsy did not show any abnormality. Assessment for tuberculosis was negative. The diagnosis of sarcoidosis was considered. Oral prednisone therapy allowed total remission., (© 2024 The Authors. Published by Elsevier Inc. on behalf of University of Washington.)

Published
2024
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49. Focal pyomyositis caused by Enterobacter in an immunocompetent patient: A case report.

Author

Tounsi H, Jlidi M, Skouri W, Bachrouch S, Alaya Z, Farhat E, Sbaihi S, Bachalli A, and Amri R

Abstract

Pyomyositis is a pyogenic infection of skeletal striated muscle, usually found in tropical areas, often in immunocompromised patients. We report a new observation of a nontropical Enterobacter pyomyositis occurring in an immunocompetent female in Tunisia. A 53-year-old patient presented with acute fever and intense myalgia in the right thigh. On clinical examination she had an altered general condition, a fever at 40°C and an important swelling of the lateral side of the right thigh. In biology, she had an inflammatory syndrome. Blood culture had identified Enterobacter. Muscle magnetic resonance imaging showed diffuse inflammatory involvement of the vastus lateralis muscle of the right quadriceps associated with edematous infiltration of subcutaneous fatty tissues. Diagnosis of pyomyositis was retained. Antibiotic therapy initially probabilistic and then adapted to the antibiogram was initiated with a favorable outcome. Although rare outside the tropics, the potential severity of pyomyositis encourages its better knowledge., Competing Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article., (© The Author(s) 2024.)

Published
2024
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50. High perillaldehyde content from essential oils of Ammodaucus leucotrichus subsp . leucotrichus Cosson & Durieu fruits from Aougrout (Algeria).

Author

Louail Z, Djemouai N, Bouti K, Tounsi H, and Kameli A

Abstract

The chemical composition of the essential oil produced by hydrodistillation from the fruits of Ammodaucus leucotrichus subsp. leucotrichus Cosson & Durieu collected from southern Algeria, precisely in Aougrout District (Adrar Province), was determined by GC-MS analysis. Nineteen (19) compounds, representing 85.71% of the essential oil, were found. The essential oil contained a high percentage of perillaldehyde (80.69%). This composition is compared to numerous reported essential oils of A. leucotrichus subsp. leucotrichus fruits that are found across Algeria and Morocco in various regions. The major component perillaldehyde has drawn a lot of interest in recent years due to its notable antifungal and broader antimicrobial properties, as well as its potential advantages for human health. Thus, the studied plant represents a source of this component that should be used as food additives, perfume ingredients, and in formulations of traditional medicine.

Published
2024
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