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Your search keyword '"H. Mehmet Sokmen"' showing total 4 results
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4 results on '"H. Mehmet Sokmen"'

1. Polypoid lesions detected in the upper gastrointestinal endoscopy: A retrospective analysis in 19560 patients, a single-center study of a 5-year experience in Turkey

Author

Atilla, Bulur, Kamil, Ozdil, Levent, Doganay, Oguzhan, Ozturk, Resul, Kahraman, Hakan, Demirdag, Zuhal, Caliskan, Nermin, Mutlu Bilgic, Evren, Kanat, Ayca, Serap Erden, and H, Mehmet Sokmen

Subjects
polypoid lesion, histopathology, Original Article, Endoscopy, digestive system diseases
Abstract

OBJECTIVE: In our study, we aimed to evaluate the endoscopic features such as prevalence and localization of polypoid lesions determined by us using esophagogastroduodenoscopy and histopathological characteristics of biopsy specimens taken in detail. METHODS: The data of 19,560 patients undergoing upper gastrointestinal endoscopy for any reason between 2009 and 2015 in our endoscopy unit were screened retrospectively and endoscopic and histopathological findings were analyzed in detail. RESULTS: In our study, the polypoid lesion was detected in 1.60% (n=313) of 19,560 patients. The most common localization of the polypoid lesions was determined to be gastric localization (n=301, 96.2%) and antrum with a rate of 33.5% (n=105). When 272 patients in whom biopsy specimen could be taken was investigated, the most frequently seen lesion was polyp (n=115, 43.4%). Hyperplastic polyps (n=81, 29.8%) were the most frequently seen type among all polyps. In histopathological evaluation of the lesions, the prevalence rates of intestinal metaplasia (IM), surrounding tissue IM, atrophy, dysplasia, and neoplasia (adenocarcinoma, squamous cell carcinoma, gastrointestinal stromal tumor, neuroendocrine tumor, and metastatic tumor) among premalignant lesions were determined to be 16.9%, 11.2%, 4.1%, 1.1%, and 3.7%, respectively. CONCLUSION: Polypoid lesions can be seen in endoscopic investigations. In histopathological investigations, while the vast majority of these lesions are benign polyps, some of them are diagnosed as premalignant or malignant lesions. In our study, we determined malignant lesions higher than the similar studies in the literature. This condition shows how effective endoscopic procedure and histopathological evaluation are of vital importance.

Published
2019

2. Current prevalence of intestinal metaplasia and Helicobacter pylori infection in dyspeptic adult patients from Turkey

Author

Kamil, Ozdil, Abdurrahman, Sahin, Resul, Kahraman, Bilgehan, Yuzbasioglu, Hakan, Demirdag, Turan, Calhan, Muberra S, Yilmaz, and H Mehmet, Sokmen

Subjects
Adult, Male, Metaplasia, Chi-Square Distribution, Adolescent, Helicobacter pylori, Turkey, Biopsy, Middle Aged, Helicobacter Infections, Intestines, Prevalence, Humans, Female, Precancerous Conditions
Abstract

The aim of this study was to investigate the prevalence of Helicobacter pylori (H. pylori) infection and intestinal metaplasia in adult dispeptic patients. (attending an endoscopy clinic at our training and referral hospital in Turkey).A total of 3301 consecutive dyspeptic patients, with a mean age +/- SD of 45.97 +/- 15.15 years, had two antral and two corporal biopsies, during routine upper gastrointestinal endoscopy. Patients were divided into three groups according to age; 18-40 years old, 41-60 years old and over 60 years old. Histological specimens were examined and graded according to the Updated Sydney System for H. Pylori infection and intestinal metaplasia.H. pylori was established in 2353 patients (71.3%). Intestinal metaplasia was found in 586 patients (17.8%). Of these patients, 86% (n:504) had complete and 14% (n:82) had incomplete intestinal metaplasia. Frequency and severity of H. pylori infection decreased significiantly in the older group (p0.001). Patients with intestinal metaplasia were older (53.6 +/- 14.9 years) than patients without intestinal metaplasia (44.3 +/- 14.7 years) (p0.001). There was no statistically significant relationship between intestinal metaplasia and H. pylori presence (p0.05). Intestinal metaplasia was more prevalant in patients with mild infection (21.9%) than in patients without Helicobacter pylori infection (16.3%) or with moderate (16.2%) or severe infection (14.6%) (p0.01)H. pylori infection and density decreases, while the prevalence of intestinal metaplasia and incomplete intestinal metaplasia percentage increases in older dyspeptic patients. Mild H. Pylori colonisation could be a sign of intestinal metaplasia, especially in the elderly.

Published
2011

3. Genetic diseases and molecular genetics - 2

Author

Kenneth I. Glassberg, David G. Motto, Chong Zhang, Valeriy Nosikov, E.I. Christensen, Mikhail Shvetsov, Bin Zhu, Ana Paula Rodrigues Melo, Manuela Cuccurullo, Ryszard Grenda, Vladimir Tesar, Guido Gatti, Boris Utsch, Susanna Tomasoni, Nan Chen, A. Schirinzi, Nobuaki Takagi, Maria Roszkowska-Blaim, Semiramis Jamil Adad do Monte, Eric Wise, Federica Mezzabotta, Fabien Nevo, Wolf H. Fridman, Véronique Frémeaux-Bacchi, Angela D'Angelo, Joseph H. Lee, Christian Becker, Monica Ceol, Andrea Emmert, Elena Kamyshova, Dorothee Schönfeld, Dali Dalia, Adile Akdas, Peter Nürnberg, Fatiu A Arogundade, Franca Anglani, Frank Bienaimé, Carsten A. Wagner, Céline Becker, Zhaohui Wang, Maja Krzysztalowska, Kálmán Tory, João Bosco, Ali G. Gharavi, Piera Trionfini, Malgorzata Panczyk-Tomaszewska, Maria Bracale, Martijn J. Wilmer, Abubakr Sanusi, M Merta, Vera Krane, Bruno Ranchin, Marie-Agnes Dragon-Durey, Ellen Shapiro, Andrzej Ciechanowicz, Aleksey Shestakov, Karolina Skonieczna, Rémi Salomon, Pierre Ronco, Ahmet Nayir, Dominik N. Müller, Elena Ranieri, Ilenia Bernascone, Giuseppe Remuzzi, QiuJu Liu, Faddi Fakhouri, Irina Kutyrina, Patricia L. Weng, Corinne Antignac, Massimo Attanasio, Celin Schaeffer, Jitka Stekrova, Vinay Sakhuja, Jean-Luc Andre, Sidarth Kumar Sethi, Laura Zagato, Giorgio Casari, Pauling Chu, Frank Breunig, L Salawu, Olivier Gribouval, I. Meij, Leo A. H. Monnens, Dorella Del Prete, Mustafa Solak, Mieczyslaw Litwin, Loreto Gesualdo, Nazim Denizli, P. Cerullo, Lambertus P. van den Heuvel, Christoph Wanner, Shih-Hua Lin, W. van't Hoff, P. Deen, Muheez A. Durosinmi, Christian Noel, Frank Weidemann, G. Messina, Lorena Longaretti, Pinar Ata Eren, Veronika Elisakova, Emilia Tiralongo, Ling Qin, Stanislava Svobodova, Gian Marco Ghiggeri, Marta Drozdzynska, Anne-Laure Sellier-Leclerc, Sung-Sen Yang, Jarosław Peregud-Pogorzelski, José Adail Fonseca de Castro, Chiara Lanzani, Lino Merlino, Fabrizio Dal Piaz, Cristina Malaventura, Chantal Loirat, Wen Zhang, Monica Dagnino, Marco Simonini, Vivekanand Jha, Lina Artifoni, Lorena Citterio, Gudrun Nürnberg, Grażyna Adler, Friedhelm Hildebrandt, Elisa Benetti, Lorenzo A. Calò, Michael Zirbs, Terry W. Hensle, Eduardo Machuca, Arnaud Garnier, Solmaz Erdem, Andrzej Brodkiewicz, Caroline Blanc, Audrey Pawtowski, Miriam Galbusera, Muzzamil Hassan, M. Belingheri, Hong Ren, Anita Konka, Reiterová J, Jackeline Larissa Mendes de Sousa, Yasaswi Paruchuri, Luca Rampoldi, N.V. Knoers, Milada Kohoutová, L. Rampoldi, Simona Delli Carpini, Francesco Scolari, H. Mehmet Sokmen, Annalisa Vilasi, Maddalena Gigante, O. Devuyst, Antonio Malorni, Elena Levtchenko, Nirupama Chandel, Leo A. J. Kluijtmans, Giovambattista Capasso, Sam Werzberger, Zeynep Acar, Simone Sanna-Cherchi, José Tibúrcio do Monte Neto, L. Ghio, Weiming Wang, Sophie Saunier, Xavier Jeunemaitre, Robert D. Burk, FuDe Huang, Elena Brioni, Paolo Manunta, Luisa Murer, G.M. Ghiggeri, P. K. Aggarwal, Daniela Corna, Yi-Fen Lo, Ana Maria Martins, Edgar A. Otto, Adewale Akinsola, Anatália de Brito Ribeiro da Silva, Roberto Ravazzolo, Enrica Tosetto, Dorothee Schoenfeld, Yu-Juei Hsu, Claudia Izzi, Ariela Benigni, Alan Werzberger, Matthias T.F. Wolf, Gianluca Caridi, Giuseppe Bianchi, Vânia D'Almeida, Irina Davydenko, and E.N. Levtchenko

Subjects
Genetics, Transplantation, medicine.medical_specialty, Nephrology, business.industry, Molecular genetics, medicine, business, Human genetics
Published
2009
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4. Polypoid lesions detected in the upper gastrointestinal endoscopy: A retrospective analysis in 19560 patients, a single-center study of a 5-year experience in Turkey.

Author

Bulur A, Ozdil K, Doganay L, Ozturk O, Kahraman R, Demirdag H, Caliskan Z, Mutlu Bilgic N, Kanat E, Serap Erden A, and Mehmet Sokmen H

Abstract

Objective: In our study, we aimed to evaluate the endoscopic features such as prevalence and localization of polypoid lesions determined by us using esophagogastroduodenoscopy and histopathological characteristics of biopsy specimens taken in detail., Methods: The data of 19,560 patients undergoing upper gastrointestinal endoscopy for any reason between 2009 and 2015 in our endoscopy unit were screened retrospectively and endoscopic and histopathological findings were analyzed in detail., Results: In our study, the polypoid lesion was detected in 1.60% (n=313) of 19,560 patients. The most common localization of the polypoid lesions was determined to be gastric localization (n=301, 96.2%) and antrum with a rate of 33.5% (n=105). When 272 patients in whom biopsy specimen could be taken was investigated, the most frequently seen lesion was polyp (n=115, 43.4%). Hyperplastic polyps (n=81, 29.8%) were the most frequently seen type among all polyps. In histopathological evaluation of the lesions, the prevalence rates of intestinal metaplasia (IM), surrounding tissue IM, atrophy, dysplasia, and neoplasia (adenocarcinoma, squamous cell carcinoma, gastrointestinal stromal tumor, neuroendocrine tumor, and metastatic tumor) among premalignant lesions were determined to be 16.9%, 11.2%, 4.1%, 1.1%, and 3.7%, respectively., Conclusion: Polypoid lesions can be seen in endoscopic investigations. In histopathological investigations, while the vast majority of these lesions are benign polyps, some of them are diagnosed as premalignant or malignant lesions. In our study, we determined malignant lesions higher than the similar studies in the literature. This condition shows how effective endoscopic procedure and histopathological evaluation are of vital importance., Competing Interests: Conflict of Interest: No conflict of interest was declared by the authors., (Copyright: © 2021 by Istanbul Northern Anatolian Association of Public Hospitals.)

Published
2020
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