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Objective To investigate the correlation between the polymorphism of 4 coagulation-related genes, rs1799963 （coagulation factor V gene Leiden）, rs6025 （prothrombin gene G20210A）, rs1042579 （thrombomodulin protein gene c.1418CT） and rs1801131 （methylenetetrahydroflate reductase gene） and lower extremity deep venous thrombosis （LEDVT）. Methods The 4 genotypes mentioned above of 150 LEDVT patients and 153 healthy controls were detected by the kompetitive allele specific polymerase chain reaction （KASP）, then related blood biochemical indicators were collected, binary Logistic regression was established to screen the independent risk factors of LEDVT, and the correlation between polymorphism of 4 coagulation-related genes and LEDVT and its indicators under different genetic modes after adjusting confounding factors were analyzed. Results Five variables, D-dimer, fibrinogen degradation product, homocysteine, sex and age might be the risk factors of LEDVT. These variables were put into 4 genetic inheritance models, and adjusted in binary Logistic regression. The results suggested that the mutations of rs1042579 were correlated with LEDVT under dominant inheritance mode. Conclusion The gene polymorphism of rs1799963, rs6025 and rs1801131 has no significant correlation with the formation of LEDVT. The gene polymorphism of rs1042579 plays a role under dominant inheritance mode, and might be an independent risk factor for formation of LEDVT.凝血相关基因多态性与下肢深静脉血栓形成的相关性.目的 探讨rs1799963（凝血因子V基因Leiden）、rs6025（凝血酶原基因G20210A）、rs1042579（血栓调节蛋白基因c.1418CT）及rs1801131（亚甲基四氢叶酸还原酶基因） 4个凝血相关基因的多态性与下肢深静脉血栓形成的相关性。 方法 采用竞争性等位基因特异性聚合酶链反应（kompetitive allele specific polymerase chain reaction，KASP）技术检测150例下肢深静脉血栓患者及153例健康对照者上述4个基因分型，采集相关血液生物化学指标，建立二元Logistic回归筛选下肢深静脉血栓形成的独立危险因素，校正混杂因素后在不同遗传模式下分析下肢深静脉血栓与各指标及4种凝血相关基因多态性的相关性。 结果 D-二聚体、纤维蛋白原降解产物、同型半胱氨酸、性别、年龄这5个变量可能是下肢深静脉血栓形成的危险因素。将这些变量引入4种基因遗传模式，在二元Logistic回归环境下进行校正，结果显示，rs1042579突变在显性遗传模式下与下肢深静脉血栓形成具有相关性。 结论 rs1799963、rs6025、rs1801131的基因多态性与下肢深静脉血栓形成无明显相关性，rs1042579的基因多态性在显性遗传模式下发挥作用，可能是下肢深静脉血栓形成的独立危险因素。.法医病理学；法医遗传学；深静脉血栓形成；基因多态性；凝血；肺栓塞；竞争性等位基因特异性聚合酶链反应.

Solar energy resource is highly rich in Inner Mongolia regions, and the customers utilized electric are scattered in the vast grassland. Thus, the distributed generation with its unique performance and high quality, has been developed rapidly in recent years. However, the large-scale distributed power supply has brought many unpredictable impacts when they are accessed to the distribution network, even seriously affecting the safe and stable operation of the distribution network. In this work, the technical barriers caused by distributed power generation to the grid-connected have been explored. In addition, the constraints and key influencing factors of distributed generation on distribution network have also been analysed and a safe and stable operation strategy to access distributed photovoltaic power supply into the network has proposed. The results here could provide a theoretical guidance for the rapid formulation and optimization of the distributed power accessing into grid network in Inner Mongolia power grid.

Desulphurisation sorbent properties, including desulphurisation activity and mechanical strength, are important in the sulphidation/regeneration cycle for high-temperature coal gas desulphurisation. In this paper, α-Fe2O3 desulphurisation sorbent was prepared and the changes in its mechanical strength and the surface morphology after regeneration in O2, SO2 and SO2–O2 atmospheres were measured with a particle strength tester and by scanning electron microscopy. The mechanical strength of the sorbent was generally higher after regeneration, although the formation and decomposition of sulphate during regeneration decreased the mechanical strength of the sorbent. The sulphate formation and decomposition depended on the O2 and SO2 concentration and the regeneration temperature. The mechanical strength was also increased by the sorbent sintering.

Adipocyte fatty acid-binding protein (A-FABP), the most abundant FABP in adipocytes, controls fatty acid uptake, transport, and metabolism in fat cells. We constructed a transgenic mice model that overexpressed the cattle A-FABP gene to investigate the relationship between A-FABP expression and intermuscular fat deposition. There was no significant difference in body weight and serum biochemical indexes between transgenic and wild-type mice. Further, there were no significant differences in intermuscular triglyceride content and A-FABP expression levels over three generations of transgenic mice. However, abdominal adipose rate, A-FABP protein content, and intermuscular triglyceride levels of transgenic mice were significantly higher than those of wild-type mice. In addition, triglycerides were remarkably higher in the skeletal muscle but lower in the myocardium of transgenic mice. Thus, overexpression of cattle A-FABP gene promoted fat deposition in the skeletal muscle of transgenic mice.

To investigate the time-dependent expression of metallothionein （MT） 1A mRNA and MT2A mRNA in contused skeletal muscle of rats.A total of 54 Sprague-Dawley rats were used in this study. The rats were divided into two parts: control group （The expression trends of the two potential marker genes were related to wound age. In addition to 0.5 h, there were significant contrasts between the control group and contused group （Determination of MT1A mRNA and MT2A mRNA levels by real-time PCR may be useful for the estimation of wound age.

Stretching dominated Kagome lattices reinforced by carbon fibers were designed and manufactured. The sandwich panels were assembled with bonded laminate skins. The mechanical behaviors of the sandwich panels were tested by out-of-plane compression, in-plane compression and three-point bending. Different failure modes of the sandwich structures were revealed. The experimental results showed that the carbon fiber reinforced lattice grids are much stiffer and stronger than foams and honeycombs. It was found that buckling and debonding dominate the mechanical behavior of the sandwich structures, and that more complaint skin sheets might further improve the overall mechanical performance of the sandwich panels.

To acquire materials of higher specific stiffness and strength, stretching dominated lattice materials reinforced by carbon fibers were designed and manufactured. The mechanical behaviors were predicted and experimented. The imperfections of lattice materials, such as the waviness of the struts, non-circular cross-sections and cantilever ribs, greatly influenced their performance. The bending effects of the imperfections were predicted and compared with the experiment results. Although influenced by the imperfections, carbon reinforced lattice materials are still much stiffer and stronger than foams and honeycombs.

We report a rare case of breast cancer concomitant with progesterone-receptor-positive renal cell carcinoma. A 48-year-old woman was diagnosed as having infiltrating ductal carcinoma of the breast and underwent modified radical mastectomy. A synchronous retroperitoneal tumour was detected by sonography of the abdomen in a routine cancer staging. Initially, the tumour was diagnosed as a synchronous retroperitoneal metastasis by needle biopsy; further tests revealed that it was progesterone receptor-positive. The retroperitoneal tumour showed poor response to full courses of adjuvant chemotherapy for breast cancer. Subsequently, the patient underwent a radical operation that included nephrectomy. The final pathology confirmed a sarcomatoid renal cell carcinoma. The post-operative course was uneventful. The patient had no recurrence at the 1-year follow-up. In this report, accurate diagnosis and adequate treatment were discussed. An intra-abdominal tumour with progesterone receptor- (PR) positive features is usually considered to be metastatic in breast cancer patients. For breast cancer patients with a PR-positive retroperitoneal tumour, renal cell carcinoma should be differentiated from a metastatic lesion of breast cancer, even if PR-expression is rare in renal cell carcinoma. To the best of our knowledge, this is the first case of PR-positive expression in breast cancer concomitant with renal carcinoma. In clinical settings, it is challenging for the surgeon to make an accurate diagnosis and to provide prompt treatment in such cases.

Objective To assess perioperative and short-term outcomes after tension-free vaginal mesh repair of pelvic organ prolapse in local Chinese women. Design Case series. Setting The urogynaecology unit of a university teaching hospital in Hong Kong. Patients All women with stage III or more pelvic organ prolapse who underwent tension-free vaginal mesh repair with or without vaginal hysterectomy from May 2007 to June 2011. Main outcome measures Perioperative and short-term outcomes. Results In all, 47 women underwent the procedure during the study period. The mean operating time was 94 minutes, the mean estimated blood loss was 163 mL, and the mean hospital stay was 4 days. Four patients had visceral injuries, all of which were identified and repaired during the operation; all four patients recovered uneventfully. The mean duration of follow-up was 25 (standard deviation, 13) months. Pelvic organ prolapse quantification improved significantly; nine (19%) of the patients had recurrent stage II prolapse but only one was symptomatic, six (13%) had postoperative mesh exposure, three of whom underwent mesh excision. There were five (11%) who had de-novo urodynamic stress incontinence, which was mostly mild and managed conservatively. Overall 91% (43/47) were satisfied with their operative outcome. Conclusions The success rate of tension-free vaginal mesh repair for the treatment of pelvic organ prolapse in local Chinese women was comparable to rates reported internationally. There was a high degree of subjective satisfaction with the procedure. There were low rates of mesh exposure and de-novo stress incontinence that was mostly asymptomatic or mild.