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Le carcinome adenoide kystique (CAK) du sein est une tumeur rare representant environ 0,1 % des cancers du sein. Contrairement a d’autres localisations, le CAK du sein est une tumeur maligne a marche lente. Nous en rapportons deux observations chez deux femmes âgees, respectivement, de 45 et 46 ans qui consultaient pour un nodule mammaire mesurant, respectivement 1,5 et 2,5 cm. A l’echomammographie, il s’agissait d’une tumeur assez bien limitee avec composante kystique pour la premiere patiente et mal limitee pour la seconde. Une cytoponction etait pratiquee pour cette derniere; elle avait conclu a un carcinome canalaire infiltrant. L’examen histologique des pieces de mastectomie partielle avait conclu au diagnostic de CAK, confirmepar l’etude immunohistochimique. La premiere patiente avait beneficied’une radiotherapie mammaire, alors que la seconde avait subi une mastectomie avec curage ganglionnaire, suivie d’une radiotherapie. L’evolution etait bonne pour les deux cas avec un recul de trois ans et un an, respectivement. L’objectif de ce travail est de preciser les particularites anatomocliniques et therapeutiques ainsi que le pronostic de ce type rare de tumeur mammaire.

The present study was carried out to determine the changes in proximate composition and physicochemical characteristics of flaxseed during germination. Flaxseed was germinated for 4 days and observations were taken every day throughout the study. Changes in the seed reserve and antioxidant activity were determined during germination. The oil content of the cultivar decreased from 35.10 to 27.22%. During the germination period, the total protein content increased to 23.84%. Germinated flaxseed showed significantly higher unsaturated as compared to saturated fatty acid ratios and higher calculated oxidizability (Cox) values. The Saponification value ranged from 182 to 192 mg KOH·g –1 oil during germination. The highest peroxide value (2.4 mequiv O 2 ·kg −1 oil) was observed at the end of germination. The unsaponifiable contents ranged from 1.62 to 1.18%. The oxidation value of the oil samples were statistically in the same range (4.1–6.4%). After 4 days of germination, oil stability was reduced to 1.0 h. The increase in ascorbic acid content was steady. Total phenolic acid contents differed significantly. The greatest concentration was detected in non germinated flaxseed oil. Germinated Flaxssed oil showed an important free radical scavenging activity towards 1-1-diphenyl-2-picrylhydrazyl (DPPH) free radicals.