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Your search keyword '"Hübner, Sabine"' showing total 97 results
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97 results on '"Hübner, Sabine"'

1. Optomagnetic forces on YIG/YFeO3 microspheres levitated in chiral hollow-core photonic crystal fibre

Author

Chakraborty, Soumya, Wong, Gordon K. L., Oda, Ferdi, Wachter, Vanessa, Kusminskiy, Silvia Viola, Yokosawa, Tadahiro, Hübner, Sabine, Zubiri, Benjamin Apeleo, Spiecker, Erdmann, Distaso, Monica, Russell, Philip St. J., and Joly, Nicolas Y.

Subjects
Physics - Optics, Physics - Applied Physics
Abstract

We explore a magnetooptomechanical system consisting of a single magnetic microparticle optically levitated within the core of a helically twisted single-ring hollow-core photonic crystal fibre. We use newly-developed magnetic particles that have a core of antiferromagnetic yttrium-ortho-ferrite (YFeO3) and a shell of ferrimagnetic YIG (Y3Fe5O12) approximately 50 nm thick. Using a 632.8 nm probe beam, we observe optical-torque-induced rotation of the particle and rotation of the magnetization vector in presence of an external static magnetic field. This one-of-a-kind platform opens a path to novel investigations of optomagnetic physics with levitated magnetic particles.

Published
2024

6. Controlled Self-Assembly of Gold Nanotetrahedra into Quasicrystals and Complex Periodic Supracrystals

Author

Wang, Yi, primary, Chen, Jun, additional, Li, Ruipeng, additional, Götz, Alexander, additional, Drobek, Dominik, additional, Przybilla, Thomas, additional, Hübner, Sabine, additional, Pelz, Philipp, additional, Yang, Lin, additional, Apeleo Zubiri, Benjamin, additional, Spiecker, Erdmann, additional, Engel, Michael, additional, and Ye, Xingchen, additional

Published
2023
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11. Preparation of geometrically highly controlled Ga particle arrays on quasi-planar nanostructured surfaces as a SCALMS model system

Author

Hofer, André, primary, Taccardi, Nicola, additional, Moritz, Michael, additional, Wichmann, Christoph, additional, Hübner, Sabine, additional, Drobek, Dominik, additional, Engelhardt, Matthias, additional, Papastavrou, Georg, additional, Spiecker, Erdmann, additional, Papp, Christian, additional, Wasserscheid, Peter, additional, and Bachmann, Julien, additional

Published
2023
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13. Molecular mechanisms of the glucocorticoid receptor in steroid therapy – lessons from transgenic mice

Author

Hübner Sabine and Tuckermann Jan

Subjects
conditional knockout mice, glucocorticoid receptor, inflammation, osteoporosis, Biology (General), QH301-705.5
Abstract

Glucocorticoids (GCs) are potent anti-inflammatory agents that are used to treat chronic inflammatory diseases, allergic conditions, and some cancers. However, their therapeutic effects are hampered by severe side effects, such as muscle weakness, insulin resistance, fat redistribution, and osteoporosis. GCs act on many cell types that express the GC receptor (GR) via several modes of action. One of them includes GR homodimers recognizing binding sequences in the DNA of gene promoters. Another mode involves the modulation of other DNA-bound transcription factors via dimer-independent mechanisms. To what extent these mechanisms contribute to GC-mediated effects is currently being elucidated from analyses of mice with conditional and function-selective mutations of the GR and is summarized in this review. Whether GR homodimerization or its monomer activity is decisive in the therapeutic effectiveness and associated side effects of GCs for the treatment of inflammatory conditions depends on the type of the pathological condition. Thus, the classic criterion for selective GR modulators, discrimination between GR dimer- and GR monomer-dependent protein-protein interaction, will not help in any condition to avoid side effects and maintain anti-inflammatory activity. Rather, novel criteria for selective GR modulators have to be defined that take into consideration the tissue-specific mechanisms of the GR to achieve optimized anti-inflammatory therapies with reduced side effects. In the case of avoiding osteoporosis as a side effect, a first example of such optimized compounds can be provided.

Published
2012
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15. Use of the β-Glucan-Producing Lactic Acid Bacteria Strains Levilactobacillus brevis and Pediococcus claussenii for Sourdough Fermentation—Chemical Characterization and Chemopreventive Potential of In Situ-Enriched Wheat and Rye Sourdoughs and Breads

Author

Schlörmann, Wiebke, primary, Bockwoldt, Julia A., additional, Hübner, Sabine M., additional, Wittwer, Elisa, additional, Reiners, Sarah, additional, Lorkowski, Stefan, additional, Dawczynski, Christine, additional, Ehrmann, Matthias A., additional, and Glei, Michael, additional

Published
2022
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28. Use of the β-Glucan-Producing Lactic Acid Bacteria Strains Levilactobacillus brevis and Pediococcus claussenii for Sourdough Fermentation_Chemical Characterization and Chemopreventive Potential of In Situ-Enriched Wheat and Rye Sourdoughs and Breads

Author

Schlörmann, Wiebke, Bockwoldt, Julia A., Hübner, Sabine M., Wittwer, Elisa, Reiners, Sarah, Lorkowski, Stefan, Dawczynski, Christine, Ehrmann, Matthias A., and Glei, Michael

Subjects
Article, β-glucan, colon cancer, chemoprevention, lactic acid bacteria, sourdough, bread, ddc
Published
2021

34. Reise in eine versunkene Welt : Eine Nubienexpedition im Fruhjahr 1900

Author

Huebner, Sabine R. and Huebner, Sabine R.

Subjects
Diaries, History, Notebooks, sketchbooks, etc, Egyptology--History--20th century.--Nubia, E´gyptologie--Histoire--20e sie`cle.--Nubie, Antiquities, Egyptology
Abstract

Im Fruhjahr 1900 unternahm eine Gruppe deutscher Wissenschaftler eine Expedition in das Gebiet zwischen dem ersten und zweiten Nilkatarakt im heutigen Sudan. Der 26-jahrige klassische Archaologe Hermann Thiersch (1874 - 1939), spaterer Ordinarius und Rektor der Universitat Gottingen, war mit von der Partie und hielt in einem Reisetagebuch und zahlreichen Skizzen seine Eindrucke dieser Nubienexpedition fest. Mit den beteiligten Agyptologen studierte er die archaologischen Hinterlassenschaften der Grenzfestungen des alten Agypten. Noch grosseres Augenmerk widmete er aber den Gefahren und Beschwerlichkeiten der abenteuerlichen Reise, dem Alltagsleben der nubischen Bevolkerung und der Kulturgeschichte dieser jahrtausendealten Grenzregion zwischen Agypten und Zentralafrika, die heute unwiederbringlich in den Fluten des Nasserstausees versunken ist.

Published
2021

37. Betriebsvergleich 2016/17: Gute Ergebnisse im Zierpflanzenbau.

Author

Hübner, Sabine

Subjects
ORNAMENTAL horticulture, HORTICULTURE, PLANT classification, ORNAMENTAL plants
Abstract

This article discusses about good results in ornamental plant cultivation. It is noted that the ornamental plant cultivation companies that sell indirectly will be after the predominantly produced cultures in potted and cut flower businesses. It also analyzes a subgroup of the potted plants establishment for predominantly bedding and Produce balcony plants.

Published
2019

46. Glucocorticoid receptor dimerization is required for survival in septic shock via suppression of interleukin‐1 in macrophages

Author

Kleiman, Anna, primary, Hübner, Sabine, additional, Parkitna, Jan M. Rodriguez, additional, Neumann, Anita, additional, Hofer, Stefan, additional, Weigand, Markus A., additional, Bauer, Michael, additional, Schmid, Wolfgang, additional, Schütz, Gunter, additional, Libert, Claude, additional, Reichardt, Holger M., additional, and Tuckermann, Jan P., additional

Published
2011
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50. Glucocorticoid receptor dimerization is required for survival in septic shock via suppression of interleukin-1 in macrophages.

Author

Kleiman, Anna, Hübner, Sabine, Parkitna, Jan M. Rodriguez, Neumann, Anita, Hofer, Stefan, Weigand, Markus A., Bauer, Michael, Schmid, Wolfgang, Schütz, Günter, Libert, Claude, Reichardt, Holger M., and Tuckermann, Jan P.

Subjects
*SEPSIS, *GLUCOCORTICOIDS, *ANTI-inflammatory agents, *TRANSCRIPTION factors, *LIPOPOLYSACCHARIDES
Abstract

Sepsis is controlled by endogenous glucocorticoids (GCs). Previous studies provided evidence that crosstalk of the monomeric GC receptor (GR) with proinflammatory transcription factors is the crucial mechanism underlying the suppressive GC effect. Here we demonstrate that mice with a dimerization-deficient GR (GRdim) are highly susceptible to sepsis in 2 different models, namely cecal ligation and puncture and lipopolysaccharide (LPS)-induced septic shock. TNF-α is normally regulated in these mice, but down-regulation of IL-6 and IL-1β is diminished. LPS-treated macrophages derived from GRdim mice are largely resistant to GC actions in vitro in terms of morphology, surface marker expression, and gene expression. Treatment with recombinant IL-1 receptor antagonist improved survival of GRdim mice and mice lacking the GR in macrophages (GRLysMCre) mice. This suggests that regulation of IL-1β in macrophages by GCs is pivotal to control sepsis. [ABSTRACT FROM AUTHOR]

Published
2012
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