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150 results on '"Hötzenecker, Wolfram"'

6. Baseline metastatic growth rate is an independent prognostic marker in patients with advanced BRAF V600 mutated melanoma receiving targeted therapy

Author

Wagner, Nikolaus B., Lenders, Max M., Kühl, Kathrin, Reinhardt, Lydia, Fuchß, Milena, Ring, Natalie, Stäger, Ramon, Zellweger, Caroline, Ebel, Chiara, Kimeswenger, Susanne, Oellinger, Angela, Amaral, Teresa, Forschner, Andrea, Leiter, Ulrike, Klumpp, Bernhard, Hoetzenecker, Wolfram, Terheyden, Patrick, Mangana, Joanna, Loquai, Carmen, Cozzio, Antonio, Garbe, Claus, Meier, Friedegund, Eigentler, Thomas K., and Flatz, Lukas

Published
2024
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7. Development of a Cellular Assay as a Personalized Model for Testing Chronic Wound Therapeutics

Author

Doerfler, Petra, Schoefmann, Nicole, Cabral, Gabriela, Bauer, Wolfgang, Berli, Martin C., Binder, Barbara, Borst, Carina, Botter, Sander, French, Lars E., Goerge, Tobias, Hafner, Juerg, Hartmann, Daniela, Høgh, Annette, Hoetzenecker, Wolfram, Holzer-Geissler, Judith C.J., Kamolz, Lars P., Kofler, Katrin, Luger, Thomas, Nischwitz, Sebastian P., Popovits, Michael, Rappersberger, Klemens, Restivo, Gaetana, Schlager, Justin G., Schmuth, Matthias, Stingl, Georg, Stockinger, Theresa, Stroelin, Anke, Stuetz, Anton, Umlauft, Julian, Weninger, Wolfgang P., and Wolff-Winiski, Barbara

Published
2024
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9. Detecting cutaneous basal cell carcinomas in ultra-high resolution and weakly labelled histopathological images

Author

Kimeswenger, Susanne, Rumetshofer, Elisabeth, Hofmarcher, Markus, Tschandl, Philipp, Kittler, Harald, Hochreiter, Sepp, Hötzenecker, Wolfram, and Klambauer, Günter

Subjects
Electrical Engineering and Systems Science - Image and Video Processing, Computer Science - Machine Learning, Statistics - Machine Learning
Abstract

Diagnosing basal cell carcinomas (BCC), one of the most common cutaneous malignancies in humans, is a task regularly performed by pathologists and dermato-pathologists. Improving histological diagnosis by providing diagnosis suggestions, i.e. computer-assisted diagnoses is actively researched to improve safety, quality and efficiency. Increasingly, machine learning methods are applied due to their superior performance. However, typical images obtained by scanning histological sections often have a resolution that is prohibitive for processing with current state-of-the-art neural networks. Furthermore, the data pose a problem of weak labels, since only a tiny fraction of the image is indicative of the disease class, whereas a large fraction of the image is highly similar to the non-disease class. The aim of this study is to evaluate whether it is possible to detect basal cell carcinomas in histological sections using attention-based deep learning models and to overcome the ultra-high resolution and the weak labels of whole slide images. We demonstrate that attention-based models can indeed yield almost perfect classification performance with an AUC of 0.99., Comment: Machine Learning for Health (ML4H) at NeurIPS 2019

Published
2019

15. Immunologically relevant aspects of the new COVID-19 vaccines—an ÖGAI (Austrian Society for Allergology and Immunology) and AeDA (German Society for Applied Allergology) position paper

Author

Untersmayr, Eva, Förster-Waldl, Elisabeth, Bonelli, Michael, Boztug, Kaan, Brunner, Patrick M., Eiwegger, Thomas, Eller, Kathrin, Göschl, Lisa, Grabmeier-Pfistershammer, Katharina, Hötzenecker, Wolfram, Jordakieva, Galateja, Moschen, Alexander R., Pfaller, Birgit, Pickl, Winfried, Reinisch, Walter, Wiedermann, Ursula, Klimek, Ludger, Bergmann, Karl-Christian, Brehler, Randolf, Pfützner, Wolfgang, Novak, Natalija, Merk, Hans, Rabe, Uta, Schlenter, Wolfgang, Ring, Johannes, Wehrmann, Wolfgang, Mülleneisen, Norbert, Wrede, Holger, Fuchs, Thomas, and Jensen-Jarolim, Erika

Published
2021
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16. Effectiveness and clinical predictors of drug survival in psoriasis patients receiving apremilast: A registry analysis

Author

Graier, Thomas, Weger, Wolfgang, Sator, Paul-Gunther, Salmhofer, Wolfgang, Gruber, Barbara, Jonak, Constanze, Kölli, Claudia, Schütz-Bergmayr, Martina, Vujic, Igor, Ratzinger, Gudrun, Häring, Nina, Painsi, Clemens, Prillinger, Knut, Mlynek, Alexander, Skvara, Hans, Trattner, Hannes, Tanew, Adrian, Lichem, Roland, Ellersdorfer, Christina, Legat, Franz, Gruber-Wackernagel, Alexandra, Hofer, Angelika, Schmiedberger, Erich, Hoetzenecker, Wolfram, Müllegger, Robert, Saxinger, Werner, Quehenberger, Franz, and Wolf, Peter

Published
2021
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17. Practical handling of allergic reactions to COVID-19 vaccines: A position paper from German and Austrian Allergy Societies AeDA, DGAKI, GPA and ÖGAI

Author

Klimek, Ludger, Bergmann, Karl-Christian, Brehler, Randolf, Pfützner, Wolfgang, Zuberbier, Torsten, Hartmann, Karin, Jakob, Thilo, Novak, Natalija, Ring, Johannes, Merk, Hans, Hamelmann, Eckard, Ankermann, Tobias, Schmidt, Sebastian, Untersmayr, Eva, Hötzenecker, Wolfram, Jensen-Jarolim, Erika, Brockow, Knut, Mahler, Vera, and Worm, Margitta

Published
2021
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21. Entwicklung der Patientencharakteristika und der Wirksamkeit der Biologika‐Therapie bei Patienten des Österreichischen Psoriasis‐Registers von 2004 bis 2022

Author

Graier, Thomas, primary, Salmhofer, Wolfgang, additional, Jonak, Constanze, additional, Weger, Wolfgang, additional, Zikeli, Claudia, additional, Gruber, Barbara, additional, Sator, Paul, additional, Prillinger, Knut, additional, Mlynek, Alexander, additional, Schütz‐Bergmayr, Martina, additional, Richter, Leo, additional, Ratzinger, Gudrun, additional, Sassmann, Christoph, additional, Painsi, Clemens, additional, Häring, Nina, additional, Wippel‐Slupetzky, Katharina, additional, Skvara, Hans, additional, Trattner, Hannes, additional, Inzinger, Martin, additional, Bangert, Christina, additional, Ellersdorfer, Christina, additional, Falkensteiner, Katharina, additional, Sadoghi, Birgit, additional, Gruber‐Wackernagel, Alexandra, additional, Hofer, Angelika, additional, Legat, Franz, additional, Lange‐Asschenfeldt, Bernhard, additional, Schmuth, Matthias, additional, Vujic, Igor, additional, Hötzenecker, Wolfram, additional, Saxinger, Werner, additional, Müllegger, Robert, additional, Quehenberger, Franz, additional, and Wolf, Peter, additional

Published
2023
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22. Evolution of characteristics and biologic treatment effectiveness in patients of the Austrian psoriasis registry from 2004–2022

Author

Graier, Thomas, primary, Salmhofer, Wolfgang, additional, Jonak, Constanze, additional, Weger, Wolfgang, additional, Zikeli, Claudia, additional, Gruber, Barbara, additional, Sator, Paul, additional, Prillinger, Knut, additional, Mlynek, Alexander, additional, Schütz‐Bergmayr, Martina, additional, Richter, Leo, additional, Ratzinger, Gudrun, additional, Sassmann, Christoph, additional, Painsi, Clemens, additional, Häring, Nina, additional, Wippel‐Slupetzky, Katharina, additional, Skvara, Hans, additional, Trattner, Hannes, additional, Inzinger, Martin, additional, Bangert, Christina, additional, Ellersdorfer, Christina, additional, Falkensteiner, Katharina, additional, Sadoghi, Birgit, additional, Gruber‐Wackernagel, Alexandra, additional, Hofer, Angelika, additional, Legat, Franz, additional, Lange‐Asschenfeldt, Bernhard, additional, Schmuth, Matthias, additional, Vujic, Igor, additional, Hötzenecker, Wolfram, additional, Saxinger, Werner, additional, Müllegger, Robert, additional, Quehenberger, Franz, additional, and Wolf, Peter, additional

Published
2023
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29. Diagnosis and treatment of Hymenoptera venom allergy

Author

Ruëff, Franziska, primary, Bauer, Andrea, additional, Becker, Sven, additional, Brehler, Randolf, additional, Brockow, Knut, additional, Chaker, Adam M., additional, Darsow, Ulf, additional, Fischer, Jörg, additional, Fuchs, Thomas, additional, Gerstlauer, Michael, additional, Gernert, Sunhild, additional, Hamelmann, Eckard, additional, Hötzenecker, Wolfram, additional, Klimek, Ludger, additional, Lange, Lars, additional, Merk, Hans, additional, Mülleneisen, Norbert K., additional, Neustädter, Irena, additional, Pfützner, Wolfgang, additional, Sieber, Wolfgang, additional, Sitter, Helmut, additional, Skudlik, Christoph, additional, Treudler, Regina, additional, Wedi, Bettina, additional, Wöhrl, Stefan, additional, Worm, Margitta, additional, and Jakob, Thilo, additional

Published
2023
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30. Melanoma Cell-Intrinsic PD-1 Receptor Functions Promote Tumor Growth

Author

Kleffel, Sonja, Posch, Christian, Barthel, Steven R., Mueller, Hansgeorg, Schlapbach, Christoph, Guenova, Emmanuella, Elco, Christopher P., Lee, Nayoung, Juneja, Vikram R., Zhan, Qian, Lian, Christine G., Thomi, Rahel, Hoetzenecker, Wolfram, Cozzio, Antonio, Dummer, Reinhard, Mihm, Martin C., Jr., Flaherty, Keith T., Frank, Markus H., Murphy, George F., Sharpe, Arlene H., Kupper, Thomas S., and Schatton, Tobias

Published
2015
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33. Allergo Journal International / Dermatological differential diagnoses in pet owners

Author

Hötzenecker, Wolfram, Altrichter, Sabine, and Currie, Antonia

Subjects
Tinea, Zoonoses, Cat scratch disease, Cowpox, Lyme disease, Swimming pool granuloma
Abstract

Pets are popular and are kept all over the world. In addition to the many positive psychosocial and physical effects, there are unfortunately, in addition to possible allergic reactions to animals, numerous diseases that can be transmitted from pets and farm animals to their owners that can negatively affect their health. These so-called zoonotic diseases are infectious diseases that are transmitted from animals to humans. The pathogens include bacteria, parasites, fungi, and viruses. Transmission of zoonotic pathogens can occur wherever there is contact with or consumption of animals or animal products. This can occur in connection with domesticated animals, in trade, in hunting, or in research. Zoonoses can also be of importance as an occupational disease in the field of livestock farming. Due to the close relationship between humans and animals, zoonotic diseases are a global public health problem that should not be underestimated. This article discusses some more common zoonoses of the skin that can be caused by pets. Version of record

Published
2023
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34. IL-4 abrogates TH17 cell-mediated inflammation by selective silencing of IL-23 in antigen-presenting cells

Author

Guenova, Emmanuella, Skabytska, Yuliya, Hoetzenecker, Wolfram, Weindl, Günther, Sauer, Karin, Tham, Manuela, Kim, Kyu-Won, Park, Ji-Hyeon, Seo, Ji Hae, Ignatova, Desislava, Cozzio, Antonio, Levesque, Mitchell P., Volz, Thomas, Köberle, Martin, Kaesler, Susanne, Thomas, Peter, Mailhammer, Reinhard, Ghoreschi, Kamran, Schäkel, Knut, Amarov, Boyko, Eichner, Martin, Schaller, Martin, Clark, Rachael A., Röcken, Martin, and Biedermann, Tilo

Published
2015

38. Immunologisch relevante Aspekte der neuen COVID-19-Impfstoffe

Author

Untersmayr, Eva, Förster-Waldl, Elisabeth, Bonelli, Michael, Boztug, Kaan, Brunner, Patrick M., Eiwegger, Thomas, Eller, Kathrin, Göschl, Lisa, Grabmeier-Pfistershammer, Katharina, Hötzenecker, Wolfram, Jordakieva, Galateja, Moschen, Alexander R., Pfaller, Birgit, Pickl, Winfried, Reinisch, Walter, Wiedermann, Ursula, Klimek, Ludger, Bergmann, Karl-Christian, Brehler, Randolf, Novak, Natalija, Merk, Hans F., Rabe, Uta, Schlenter, Wolfgang W., Ring, Johannes, Wehrmann, Wolfgang, Mülleneisen, Norbert K., Wrede, Holger, Fuchs, Thomas, and Jensen-Jarolim, Erika

Subjects
Immunsuppression, Impfwirkung, COVID-19, Immunantwort, COVID-19-Impfung, Immunmodulation, Leitlinie
Published
2021

39. Praktischer Umgang mit allergischen Reaktionen auf COVID-19-Impfstoffe

Author

Klimek, Ludger, Bergmann, Karl-Christian, Brehler, Randolf, Pfützner, Wolfgang, Worm, Margitta, Hartmann, Karin, Jakob, Thilo, Novak, Natalija, Ring, Johannes, Hamelmann, Eckard, Ankermann, Tobias, Schmidt, Sebastian M., Untersmayr, Eva, Hötzenecker, Wolfram, Jensen-Jarolim, Erika, and Zuberbier, Torsten

Subjects
mRNA-1273, mRNA-Impfstoff, Anaphylaxie, SARS-CoV-2, allergische Reaktion, COVID-19, BNT162b2, Leitlinie
Abstract

Hintergrund: Zur vorbeugenden Behandlung von COVID-19 (Coronaviruserkrankung 2019) wurden in einer beispiellosen weltweiten Forschungsanstrengung Sicherheit und Wirksamkeit neuer Impfstoffplattformen studiert, die noch nie zuvor am Menschen eingesetzt wurden. Weniger als ein Jahr nach der Entdeckung der SARS-CoV-2-Virussequenz (SARS-CoV-2, "severe acute respiratory syndrome coronavirus type 2") wurden diese in zahlreichen Ländern für den Einsatz zugelassen und es wurde mit Massenimpfungen begonnen. Die bislang in der Europäischen Union (EU) zugelassenen mRNA-Impfstoffe (mRNA, "messenger"-RNA) gegen SARS-CoV-2 BNT162b2 und mRNA-1273 basieren auf einer ähnlichen lipidbasierten Nanopartikelträgertechnologie; die Lipidkomponenten unterscheiden sich jedoch. Schwere allergische Reaktionen und Anaphylaxien nach COVID-19-Impfungen sind sehr seltene unerwünschte Nebenwirkungen, die aber aufgrund potenziell letaler Ausgänge viel Aufmerksamkeit erhalten und ein hohes Maß an Verunsicherung ausgelöst haben. Methoden: Das aktuelle Wissen zu anaphylaktischen Reaktionen auf Impfstoffe und speziell zu den derzeit neuen mRNA-COVID-19-Impfstoffen wurde zusammengestellt mittels einer Literaturanalyse durch Recherchen in Medline, Pubmed sowie den nationalen und internationalen Studien- und Leitlinienregistern, der Cochrane Library und dem Internet unter besonderer Berücksichtigung offizieller Webseiten der World Health Oranization (WHO), der Centers for Disease Control and Prevention (CDC), der European Medicines Agency (EMA), des Robert-Koch-Instituts (RKI) und des Paul-Ehrlich-Instituts (PEI). Ergebnisse: Basierend auf der internationalen Literatur und bisheriger Erfahrungen zu schweren allergischen Reaktionen im Kontext der COVID-19-Impfungen werden von einem Expertengremium Empfehlungen für Prophylaxe, Diagnostik und Therapie dieser allergischen Reaktionen gegeben. Schlussfolgerung: Vor einer COVID-19-Impfung mit den derzeit zugelassenen Impfstoffen sind Allergietests für die allermeisten Allergiker nicht notwendig. Bei allergischer/anaphylaktischer Reaktion auf den verabreichten COVID-19-Impfstoff wird eine allergologische Abklärung empfohlen, wie auch für eine kleine potenzielle Risikopopulation vor der ersten Impfung. Die Evaluierung und Zulassung von Testverfahren sollten hierfür erfolgen. Zitierweise: Klimek L, Bergmann K-C, Brehler R, Pfützner W, Zuberbier T, Hartmann K, Jakob T, Novak N, Ring J, Merk H; Hamelmann E, Ankermann T, Schmidt S, Untersmayr E, Hötzenecker W, Jensen-Jarolim E, Brockow K, Mahler V, Worm M. Practical Handling of Allergic Reactions to COVID-19 vaccines. A Position Paper from German and Austrian Allergy Societies AeDA, DGAKI, GPA and ÖGAI. Allergo J Int 2021;30:79-95 https: //doi.org/10.1007/s40629-021-00165-7

Published
2021

47. Anwendung von Biologika bei allergischen und Typ-2-entzündlichen Erkrankungen in der aktuellen Covid-19-Pandemiea, b, c

Author

Klimek, Ludger, Pfaar, Oliver, Worm, Margitta, Eiwegger, Thomas, Hagemann, Jan, Ollert, Markus, Untersmayr, Eva, Hoffmann-Sommergruber, Karin, Vultaggio, Alessandra, Agache, Ioana, Bavbek, Sevim, Bossios, Apostolos, Casper, Ingrid, Chan, Susan, Chatzipetrou, Alexia, Vogelberg, Christian, Firinu, Davide, Kauppi, Paula, Kolios, Antonios, Kothari, Akash, Matucci, Andrea, Palomares, Oscar, Szépfalusi, Zsolt, Pohl, Wolfgang, Hötzenecker, Wolfram, Rosenkranz, Alexander, Bergmann, Karl-Christian, Bieber, Thomas, Buhl, Roland, Buters, Jeroen, Darsow, Ulf, Keil, Thomas, Kleine-Tebbe, Jörg, Lau, Susanne, Maurer, Marcus, Merk, Hans, Mösges, Ralph, Saloga, Joachim, Staubach, Petra, Jappe, Uta, Rabe, Claus, Rabe, Uta, Vogelmeier, Claus, Biedermann, Tilo, Jung, Kirsten, Schlenter, Wolfgang, Ring, Johannes, Chaker, Adam, Wehrmann, Wolfgang, Becker, Sven, Freudelsperger, Laura, Mülleneisen, Norbert, Nemat, Katja, Czech, Wolfgang, Wrede, Holger, Brehler, Randolf, Fuchs, Thomas, Tomazic, Peter-Valentin, Aberer, Werner, Fink Wagner, Antje, Horak, Fritz, Wöhrl, Stefan, Niederberger-Leppin, Verena, Pali-Schöll, Isabella, Roller-Wirnsberger, Regina, Spranger, Otto, Valenta, Rudolf, Akdis, Mübecell, Matricardi, Paolo M., Spertini, François, Khaltaev, Nikolai, Michel, Jean-Pierre, Nicod, Larent, Schmid-Grendelmeier, Peter, Idzko, Marco, Hamelmann, Eckard, Jakob, Thilo, Werfel, Thomas, Wagenmann, Martin, Taube, Christian, Jensen-Jarolim, Erika, Korn, Stephanie, Hentges, Francois, Schwarze, Jürgen, O´Mahony, Liam, Knol, Edward, del Giacco, Stefano, Chivato, Tomás, Bousquet, Jean, Zuberbier, Torsten, Akdis, Cezmi, and Jutel, Marek

Subjects
Titel, SARS-CoV-2, Medizin, Immunology and Allergy, Omalizumab, Benralizumab, Dupilumab, Reslizumab, Covid-19, Telemedizin, Mepolizumab
Published
2020

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