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1,025 results on '"Häfner H"'

2. Impact of single-room contact precautions on hospital-acquisition and transmission of multidrug-resistant Escherichia coli: a prospective multicentre cohort study in haematological and oncological wards

Author

Biehl, L.M., Higgins, P., Wille, T., Peter, K., Hamprecht, A., Peter, S., Dörfel, D., Vogel, W., Häfner, H., Lemmen, S., Panse, J., Rohde, H., Klupp, E.-M., Schafhausen, P., Imirzalioglu, C., Falgenhauer, L., Salmanton-García, J., Stecher, M., Vehreschild, J.J., Seifert, H., and Vehreschild, M.J.G.T.

Published
2019
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5. Optimierung der Antibiotikaverschreibungsgüte auf sieben Normalstationen: eine prospektive Clusterstudie

Author

Scheithauer, S, Karasimos, B, Manamayil, D, Häfner, H, Lewalter, K, Mischke, K, Heintz, B, Tacke, F, Brücken, D, Lüring, C, Heidenhain, C, Tewarie, L, Hilgers, RD, and Lemmen, SW

Subjects
antibiotic resistance, ddc: 610, Antibiotikaresistenz, surveillance, antibiotic stewardship, selection, compliance, Antibiotika stewardship
Abstract

Aim: To evaluate general shortcomings and faculty-specific pitfalls as well as to improve antibiotic prescription quality (ABQ) in non-ICU wards, we performed a prospective cluster trial. Methods: An infectious-disease (ID) consulting service performed a prospective investigation consisting of three 12-week phases with point prevalence evaluation conducted once per week (=36 evaluations in total) at seven non-ICU wards, followed by assessment of sustainability (weeks 37-48). Baseline evaluation (phase 1) defined multifaceted interventions by identifying the main shortcomings. Then, to distinguish intervention from time effects, the interventions were performed in four wards, and the 3 remaining wards served as controls; after assessing effects (phase 2), the same interventions were performed in the remaining wards to test the generalizability of the interventions (phase 3). The prolonged responses after all interventions were then analyzed in phase 4. ABQ was evaluated by at least two ID specialists who assessed the indication for therapy, the adherence to the hospital guidelines for empirical therapy, and the overall antibiotic prescription quality. Results: In phase 1, 406 of 659 (62%) patients cases were adequately treated with antibiotics; the main reason for inappropriate prescription was the lack of an indication (107/253; 42%). The antibiotic prescription quality (ABQ) significantly increased, reaching 86% in all wards after the focused interventions (502/584; nDf=3, ddf=1,697, F=6.9, p=0.0001). In phase 2 the effect was only seen in wards that already participated in interventions (248/347; 71%). No improvement was seen in wards that received interventions only after phase 2 (189/295; 64%). A given indication significantly increased from about 80% to more than 90% (p90% (p

Published
2023

8. Nosokomiale Infektionen

Author

Koch, S., Häfner, H., Lemmen, W.S., Burchardi, Hilmar, editor, Larsen, Reinhard, editor, Kuhlen, Ralf, editor, Jauch, Karl-Walter, editor, and Schölmerich, Jürgen, editor

Published
2008
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17. The Prodromal Phase of Psychosis

Author

Häfner, H., Maurer, K., Miller, Tandy, editor, Mednick, Sarnoff A., editor, McGlashan, Thomas H., editor, Libiger, Jan, editor, and Johannessen, Jan Olav, editor

Published
2001
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