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3. Complementary and alternative medicine and musculoskeletal pain in the first year of adjuvant aromatase inhibitor treatment in early breast cancer patients

Author

Hack, C.C., Häberle, L., Brucker, S.Y., Janni, W., Volz, B., Loehberg, C.R., Hartkopf, A.D., Walter, C.-B., Baake, G., Fridman, A., Malter, W., Wuerstlein, R., Harbeck, N., Hoffmann, O., Kuemmel, S., Martin, B., Thomssen, C., Graf, H., Wolf, C., Lux, M.P., Bayer, C.M., Rauh, C., Almstedt, K., Gass, P., Heindl, F., Brodkorb, T., Willer, L., Lindner, C., Kolberg, H.-C., Krabisch, P., Weigel, M., Steinfeld-Birg, D., Kohls, A., Brucker, C., Schulz, V., Fischer, G., Pelzer, V., Rack, B., Beckmann, M.W., Fehm, T., Rody, A., Maass, N., Hein, A., Fasching, P.A., and Nabieva, N.

Published
2020
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4. Influence of side-effects on early therapy persistence with letrozole in post-menopausal patients with early breast cancer: Results of the prospective EvAluate-TM study

Author

Nabieva, N., Fehm, T., Häberle, L., de Waal, J., Rezai, M., Baier, B., Baake, G., Kolberg, H.-C., Guggenberger, M., Warm, M., Harbeck, N., Wuerstlein, R., Deuker, J.-U., Dall, P., Richter, B., Wachsmann, G., Brucker, C., Siebers, J.W., Popovic, M., Kuhn, T., Wolf, C., Vollert, H.-W., Breitbach, G.-P., Janni, W., Landthaler, R., Kohls, A., Rezek, D., Noesselt, T., Fischer, G., Henschen, S., Praetz, T., Heyl, V., Kühn, T., Krauss, T., Thomssen, C., Hohn, A., Tesch, H., Mundhenke, C., Hein, A., Hack, C.C., Schmidt, K., Belleville, E., Brucker, S.Y., Kümmel, S., Beckmann, M.W., Wallwiener, D., Hadji, P., and Fasching, P.A.

Published
2018
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5. Influence of patient and tumor characteristics on early therapy persistence with letrozole in postmenopausal women with early breast cancer: results of the prospective Evaluate-TM study with 3941 patients

Author

Nabieva, N., Kellner, S., Fehm, T., Häberle, L., de Waal, J., Rezai, M., Baier, B., Baake, G., Kolberg, H.-C., Guggenberger, M., Warm, M., Harbeck, N., Wuerstlein, R., Deuker, J.-U., Dall, P., Richter, B., Wachsmann, G., Brucker, C., Siebers, J.W., Fersis, N., Kuhn, T., Wolf, C., Vollert, H.-W., Breitbach, G.-P., Janni, W., Landthaler, R., Kohls, A., Rezek, D., Noesselt, T., Fischer, G., Henschen, S., Praetz, T., Heyl, V., Kühn, T., Krauss, T., Thomssen, C., Hohn, A., Tesch, H., Mundhenke, C., Hein, A., Rauh, C., Bayer, C.M., Jacob, A., Schmidt, K., Belleville, E., Brucker, S.Y., Kümmel, S., Beckmann, M.W., Wallwiener, D., Hadji, P., and Fasching, P.A.

Published
2018
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6. Evidence of Gene-Environment Interactions between Common Breast Cancer Susceptibility Loci and Established Environmental Risk Factors

Author

Nickels, S, Truong, T, Hein, R, Stevens, K, Buck, K, Behrens, S, Eilber, U, Schmidt, M, Häberle, L, Vrieling, A, Gaudet, M, Figueroa, J, Schoof, N, Spurdle, AB, Rudolph, A, Fasching, PA, Hopper, JL, Makalic, E, Schmidt, DF, Southey, MC, Beckmann, MW, Ekici, AB, Fletcher, O, Gibson, L, dos Santos Silva, I, Peto, J, Humphreys, MK, Wang, J, Cordina-Duverger, E, Menegaux, F, Nordestgaard, BG, Bojesen, SE, Lanng, C, Anton-Culver, H, Ziogas, A, Bernstein, L, Clarke, CA, Brenner, H, Müller, H, Arndt, V, Stegmaier, C, Brauch, H, Brüning, T, Harth, V, Mannermaa, A, Kataja, V, Kosma, VM, Hartikainen, JM, Lambrechts, D, Smeets, D, Neven, P, Paridaens, R, Flesch-Janys, D, Obi, N, Wang-Gohrke, S, Couch, FJ, Olson, JE, Vachon, CM, Giles, GG, Severi, G, Baglietto, L, Offit, K, John, EM, Miron, A, Andrulis, IL, Knight, JA, Glendon, G, Mulligan, AM, Chanock, SJ, Lissowska, J, Liu, J, Cox, A, Cramp, H, Connley, D, Balasubramanian, S, Dunning, AM, Shah, M, Trentham-Dietz, A, Newcomb, P, Titus, L, Egan, K, Cahoon, EK, and Rajaraman, P

Abstract

Various common genetic susceptibility loci have been identified for breast cancer; however, it is unclear how they combine with lifestyle/environmental risk factors to influence risk. We undertook an international collaborative study to assess gene-environment interaction for risk of breast cancer. Data from 24 studies of the Breast Cancer Association Consortium were pooled. Using up to 34,793 invasive breast cancers and 41,099 controls, we examined whether the relative risks associated with 23 single nucleotide polymorphisms were modified by 10 established environmental risk factors (age at menarche, parity, breastfeeding, body mass index, height, oral contraceptive use, menopausal hormone therapy use, alcohol consumption, cigarette smoking, physical activity) in women of European ancestry. We used logistic regression models stratified by study and adjusted for age and performed likelihood ratio tests to assess gene-environment interactions. All statistical tests were two-sided. We replicated previously reported potential interactions between LSP1-rs3817198 and parity (Pinteraction= 2.4×10-6) and between CASP8-rs17468277 and alcohol consumption (Pinteraction= 3.1×10-4). Overall, the per-allele odds ratio (95% confidence interval) for LSP1-rs3817198 was 1.08 (1.01-1.16) in nulliparous women and ranged from 1.03 (0.96-1.10) in parous women with one birth to 1.26 (1.16-1.37) in women with at least four births. For CASP8-rs17468277, the per-allele OR was 0.91 (0.85-0.98) in those with an alcohol intake of

Published
2013

8. Metastasierung von Pankreastumoren

Author

Häberle, L., Braren, R., Schlitter, A. M., and Esposito, I.

Abstract

Mit einer seit Jahrzehnten stagnierenden 5-Jahres-Überlebensrate von 6 % gehört das duktale Pankreaskarzinom zu den tödlichsten Malignomen überhaupt. Trotz intensiver Forschung sind die derzeit verfügbaren Therapieoptionen nicht zufriedenstellend. Da ungefähr die Hälfte der Patienten bei Diagnosestellung bereits Fernmetastasen aufweist, muss bei der Entwicklung neuer Therapiekonzepte ein Fokus auf der Metastasierung liegen. Neue Erkenntnisse aus der Grundlagenforschung liefern hierbei verschiedene interessante Ansätze: So kann beispielsweise die molekulare Analyse des Primärtumors Hinweise auf die Prognose, die Metastasierungstendenz und das Therapieansprechen eines Pankreaskarzinoms geben. Auch scheinen bestimmte Subpopulationen von Krebsstammzellen eine wichtige Rolle bei der Metastasierung von Pankreaskarzinomen zu spielen und könnten in Zukunft interessante Zielstrukturen in der Therapie darstellen. Interaktionen zwischen Tumorzellen und ihrem Mikromilieu sind ebenfalls von großer Bedeutung in der Metastasierung des Pankreaskarzinoms und bieten diverse Ansatzpunkte für neue Therapien. Bei einer wachsenden Zahl an Zelltypen und Signalwegen, die mit der Metastasierung des Pankreaskarzinoms in Zusammenhang gebracht werden, wird die nächste große Herausforderung darin bestehen, diese neuen Ansätze in die Klinik umzusetzen. With a 5-year survival rate that has remained stagnant at 6 % for decades, pancreatic ductal adenocarcinoma (PDAC) is still one of the most fatal malignancies. Despite intensive research, currently available therapy options are less than adequate. As more than half of the patients already show distant metastases at the time of diagnosis, metastatic disease should be a primary focus in the development of new therapeutic strategies. New findings from basic research provide various interesting approaches: molecular profiling of the primary tumor seems to be a possible method to gain knowledge about the prognosis, metastatic potential and therapy response of each individual case of PDAC. Certain subpopulations of cancer stem cells also seem to be of importance in metastasis of PDAC and could become potential therapeutic targets in the future. Interactions between tumor cells and their microenvironment are another crucial factor in the metastasis of pancreatic cancer and present various new starting points for potential therapies. As the number of cell types and signaling pathways that are found to play a role in PDAC metastasis continue to grow, the next big challenge will be to translate these findings into viable clinical applications.

Published
2024
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13. Predicting mammographic density with a linear ultrasound transducer

Author

Behrens, A., additional, Fasching, P.A., additional, Schwenke, E., additional, Gaß, P., additional, Häberle, L., additional, Heindl, F., additional, Heusinger, K., additional, Lotz, L., additional, Lubrich, H., additional, Preuß, C., additional, Schneider, M.O., additional, Schulz-Wendtland, R., additional, Stumpfe, F.M., additional, Uder, M., additional, Wunderle, M., additional, Zahn, A.L., additional, Hack, C.C., additional, Beckmann, M.W., additional, and Emons, J., additional

Published
2022
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15. Prevalence of SARS-CoV-2 in Pregnant Women Assessed by RT-PCR in Franconia, Germany: First Results of the SCENARIO Study (SARS-CoV-2 prEvalence in pregNAncy and at biRth In FrancOnia) = Prävalenz von SARS-CoV-2 bei schwangeren Frauen ermittelt durch RT-PCR in Franken, Deutschland: erste Ergebnisse der SCENARIO-Studie (SARS-CoV-2 prEvalence in pregNAncy and at biRth In FrancOnia)

Author

Hein, A., Kehl, S., Häberle, L., Tiemann, C., Peuker, R., Mereutanu, D., Stumpfe, F., Faschingbauer, F., Meyer-Schlinkmann, K., Koch, M., Kainer, F., Dammer, U., Philipp, H., Kladt, C., Schrauder, M., Weingärtler, S., Hanf, V., Hartmann, A., Rübner, M., Schneider, H., Lelieveld, J., Beckmann, M., Wurmthaler, L., Fasching, P., and Schneider, M.

Abstract

Purpose Detection of SARS-CoV-2-infected pregnant women admitted to maternity units during a pandemic is crucial. In addition to the fact that pregnancy is a risk factor for severe COVID-19 and that medical surveillance has to be adjusted in infected women and their offspring, knowledge about infection status can provide the opportunity to protect other patients and healthcare workers against virus transmission. The aim of this prospective observational study was to determine the prevalence of SARS-CoV-2 infection among pregnant women in the hospital setting.Material and Methods All eligible pregnant women admitted to the nine participating hospitals in Franconia, Germany, from 2 June 2020 to 24 January 2021 were included. COVID-19-related symptoms, secondary diseases and pregnancy abnormalities were documented. SARS-CoV-2 RNA was detected by RT-PCR from nasopharyngeal swabs. The prevalence of acute SARS-CoV-2 infection was estimated by correcting the positive rate using the Rogan–Gladen method. The risk of infection for healthcare workers during delivery was estimated using a risk calculator.Results Of 2414 recruited pregnant women, six were newly diagnosed RT-PCR positive for SARS-CoV-2, which yielded a prevalence of SARS-CoV-2 infection of 0.26% (95% CI, 0.10 – 0.57%). Combining active room ventilation and wearing FFP2 masks showed an estimated reduction of risk of infection for healthcare workers in the delivery room to Conclusions The prevalence of newly diagnosed SARS-CoV-2 infection during pregnancy in this study is low. Nevertheless, a systematic screening in maternity units during pandemic situations is important to adjust hygienic and medical management. An adequate hygienic setting can minimise the calculated infection risk for medical healthcare workers during patientsʼ labour.

Published
2022

16. Determinants of transplantation success with cryopreserved ovarian tissue: data from 196 women of the FertiPROTEKT network

Author

Lotz, L, Bender-Liebenthron, J, Dittrich, R, Häberle, L, Beckmann, M W, Germeyer, A, Korell, M, Sänger, N, Kruessel, J S, and von Wolff, M

Subjects
610 Medizin und Gesundheit
Abstract

STUDY QUESTION What are the pregnancy and live birth rates for ovarian tissue transplantation and which factors are associated with the success rate? SUMMARY ANSWER Pregnancy and live birth rates per transplanted woman are 32.7% and 26.5% and success rate is associated with female age and first versus repeated transplantation. WHAT IS KNOWN ALREADY Live birth rates after ovarian tissue transplantations have been reported to be between around 24% and 41% per patient. Success rates seem to be negatively associated with increasing female age at the time of tissue cryopreservation and with pelvic radiation. Success rates are apparently not reduced after overnight transportation of ovarian tissue before freezing. STUDY DESIGN, SIZE, DURATION Registry analysis of 244 transplantations in 196 women, performed by 26 FertiPROTEKT network centres from 2007 to 2019 with follow-up till December 2020. PARTICIPANTS/MATERIALS, SETTING, METHODS Orthotopic ovarian tissue transplantations were performed in 196 women, 191 with previous malignant and 5 with previous non-malignant diseases. Size of transplanting centres varied between 1 and 100 transplantations per centre (median: 2). Factors possibly associated with success rate such as female age, first and repeated transplantation, experience of the transplanting centre and overnight transportation of the ovarian tissue before freezing were analysed. MAIN RESULTS AND THE ROLE OF CHANCE Average age of all 196 transplanted women was 31.3 years (SD 5.2; range 17-44) at the time of cryopreservation of tissue and 35.9 years (SD 4.8; range 23-47) at the time of transplantation. Pregnancy rate was 30.6% (95% CI, 24.2-37.6%) per first transplantation and 32.7% (95% CI, 26.1-39.7%) per patient. Pregnancy rate was higher after first transplantation (30.6% (95% CI, 24.2-37.6%)) compared to second and subsequent transplantations (11.8% (95% CI, 3.3-27.5%)). Live birth rate per first transplantation was 25.0% (95% CI, 19.1-31.7%) and per patient 26.5% (95% CI, 20.5-33.3%). Success rate decreased with increasing age at the time of ovarian tissue freezing. Live birth rate was 28.2% (95% CI, 20.9-36.3%) in women 35 years. Pregnancy rates after first transplantation were higher in centres who had performed ≥10 transplantations (35.1%) compared to centres with

Published
2022
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21. Expression of disialoganglioside GD2 and prognosis in breast cancer subtypes

Author

Gaß, P, additional, Kailayangiri, S, additional, Huebner, H, additional, Ruebner, M, additional, Hartmann, A, additional, Häberle, L, additional, Meyer, J, additional, Völkl, S, additional, Mackensen, A, additional, Landgraf, L, additional, Schulz-Wendtland, R, additional, Farwick, N, additional, Rossig, C, additional, Beckmann, MW, additional, Fasching, PA, additional, and Erber, R, additional

Published
2021
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22. Detektion lokoregionärer Lymphknotenmetastasen bei Patientinnen mit neu diagnostiziertem Mammakarzinom in der Zeit des PET/MRT

Author

Morawitz, J, additional, Bruckmann, N, additional, Dietzel, F, additional, Ullrich, T, additional, Bittner, A, additional, Mohrmann, S, additional, Häberle, L, additional, Ingenwerth, M, additional, Sawicki, L, additional, Umutlu, L, additional, Herrmann, K, additional, Antoch, G, additional, and Kirchner, J, additional

Published
2021
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27. Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses

Author

Zhang, H, Ahearn, TU, Lecarpentier, J, Barnes, D, Beesley, J, Qi, G, Jiang, X, O’Mara, TA, Zhao, N, Bolla, MK, Dunning, AM, Dennis, J, Wang, Q, Ful, ZA, Aittomäki, K, Andrulis, IL, Anton-Culver, H, Arndt, V, Aronson, KJ, Arun, BK, Auer, PL, Azzollini, J, Barrowdale, D, Becher, H, Beckmann, MW, Behrens, S, Benitez, J, Bermisheva, M, Bialkowska, K, Blanco, A, Blomqvist, C, Bogdanova, NV, Bojesen, SE, Bonanni, B, Bondavalli, D, Borg, A, Brauch, H, Brenner, H, Briceno, I, Broeks, A, Brucker, SY, Brüning, T, Burwinkel, B, Buys, SS, Byers, H, Caldés, T, Caligo, MA, Calvello, M, Campa, D, Castelao, JE, Chang-Claude, J, Chanock, SJ, Christiaens, M, Christiansen, H, Chung, WK, Claes, KBM, Clarke, CL, Cornelissen, S, Couch, FJ, Cox, A, Cross, SS, Czene, K, Daly, MB, Devilee, P, Diez, O, Domchek, SM, Dörk, T, Dwek, M, Eccles, DM, Ekici, AB, Evans, DG, Fasching, PA, Figueroa, J, Foretova, L, Fostira, F, Friedman, E, Frost, D, Gago-Dominguez, M, Gapstur, SM, Garber, J, García-Sáenz, JA, Gaudet, MM, Gayther, SA, Giles, GG, Godwin, AK, Goldberg, MS, Goldgar, DE, González-Neira, A, Greene, MH, Gronwald, J, Guénel, P, Häberle, L, Hahnen, E, Haiman, CA, Hake, CR, Hall, P, Hamann, U, Harkness, EF, Heemskerk-Gerritsen, BAM, Hillemanns, P, Hogervorst, FBL, Holleczek, B, Hollestelle, A, Hooning, MJ, Hoover, RN, Hopper, JL, Howell, A, Huebner, H, Hulick, PJ, Imyanitov, EN, Isaacs, C, Izatt, L, Jager, A, Jakimovska, M, Jakubowska, A, James, P, Janavicius, R, Janni, W, John, EM, Jones, ME, Jung, A, Kaaks, R, Kapoor, PM, Karlan, BY, Keeman, R, Khan, S, Khusnutdinova, E, Kitahara, CM, Ko, Y-D, Konstantopoulou, I, Koppert, LB, Koutros, S, Kristensen, VN, Laenkholm, A-V, Lambrechts, D, Larsson, SC, Laurent-Puig, P, Lazaro, C, Lazarova, E, Lejbkowicz, F, Leslie, G, Lesueur, F, Lindblom, A, Lissowska, J, Lo, W-Y, Loud, JT, Lubinski, J, Lukomska, A, MacInnis, RJ, Mannermaa, A, Manoochehri, M, Manoukian, S, Margolin, S, Martinez, ME, Matricardi, L, McGuffog, L, McLean, C, Mebirouk, N, Meindl, A, Menon, U, Miller, A, Mingazheva, E, Montagna, M, Mulligan, AM, Mulot, C, Muranen, TA, Nathanson, KL, Neuhausen, SL, Nevanlinna, H, Neven, P, Newman, WG, Nielsen, FC, Nikitina-Zake, L, Nodora, J, Offit, K, Olah, E, Olopade, OI, Olsson, H, Orr, N, Papi, L, Papp, J, Park-Simon, T-W, Parsons, MT, Peissel, B, Peixoto, A, Peshkin, B, Peterlongo, P, Peto, J, Phillips, K-A, Piedmonte, M, Plaseska-Karanfilska, D, Prajzendanc, K, Prentice, R, Prokofyeva, D, Rack, B, Radice, P, Ramus, SJ, Rantala, J, Rashid, MU, Rennert, G, Rennert, HS, Risch, HA, Romero, A, Rookus, MA, Rübner, M, Rüdiger, T, Saloustros, E, Sampson, S, Sandler, DP, Sawyer, EJ, Scheuner, MT, Schmutzler, RK, Schneeweiss, A, Schoemaker, MJ, Schöttker, B, Schürmann, P, Senter, L, Sharma, P, Sherman, ME, Shu, X-O, Singer, CF, Smichkoska, S, Soucy, P, Southey, MC, Spinelli, JJ, Stone, J, Stoppa-Lyonnet, D, Swerdlow, AJ, Szabo, CI, Tamimi, RM, Tapper, WJ, Taylor, JA, Teixeira, MR, Terry, M, Thomassen, M, Thull, DL, Tischkowitz, M, Toland, AE, Tollenaar, RAEM, Tomlinson, I, Torres, D, Troester, MA, Truong, T, Tung, N, Untch, M, Vachon, CM, van den Ouweland, AMW, van der Kolk, LE, van Veen, EM, vanRensburg, EJ, Vega, A, Wappenschmidt, B, Weinberg, CR, Weitzel, JN, Wildiers, H, Winqvist, R, Wolk, A, Yang, XR, Yannoukakos, D, Zheng, W, Zorn, KK, Milne, RL, Kraft, P, Simard, J, Pharoah, PDP, Michailidou, K, Antoniou, AC, Schmidt, MK, Chenevix-Trench, G, Easton, DF, Chatterjee, N, and García-Closas, M

Abstract

Breast cancer susceptibility variants frequently show heterogeneity in associations by tumor subtype1,2,3. To identify novel loci, we performed a genome-wide association study including 133,384 breast cancer cases and 113,789 controls, plus 18,908 BRCA1 mutation carriers (9,414 with breast cancer) of European ancestry, using both standard and novel methodologies that account for underlying tumor heterogeneity by estrogen receptor, progesterone receptor and human epidermal growth factor receptor 2 status and tumor grade. We identified 32 novel susceptibility loci (P

Published
2020

28. Einfluss der Familienanamnese eines Mamma- oder Ovarialkarzinoms auf die pathologische Komplettremission und die Prognose bei Patientinnen mit einem Mammakarzinom nach neoadjuvanter Chemotherapie

Author

Gaß, P, additional, Häberle, L, additional, Hein, A, additional, Jud, SM, additional, Lux, MP, additional, Hack, CC, additional, Emons, J, additional, Heindl, F, additional, Nabieva, N, additional, Loehberg, CR, additional, Schulz-Wendtland, R, additional, Hartmann, A, additional, Beckmann, MW, additional, Fasching, PA, additional, and Wunderle, M, additional

Published
2020
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30. Nutzung eines molekularen Registers (PRAEGNANT) zur Patienten-Selektion und Biomarker-Analyse für die SHERBOC Studie

Author

Huebner, H, additional, Kurbacher, C, additional, Kuesters, G, additional, Hartkopf, AD, additional, Lux, MP, additional, Huober, J, additional, Volz, B, additional, Taran, FA, additional, Overkamp, F, additional, Tesch, H, additional, Häberle, L, additional, Lüftner, D, additional, Wallwiener, M, additional, Müller, V, additional, Beckmann, MW, additional, Belleville, E, additional, Untsch, M, additional, Janni, W, additional, Fehm, TN, additional, Kohlberg, HC, additional, Wallwiener, D, additional, Brucker, SY, additional, Schneeweiss, A, additional, Ettl, J, additional, Ruebner, M, additional, and PA, Fasching, additional

Published
2020
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31. Einfluss der Familienanamnese eines Mamma- oder Ovarialkarzinoms auf die pathologische Komplettremission und die Prognose bei Patientinnen mit einem Mammakarzinom nach neoadjuvanter Chemotherapie

Author

Wunderle, M, additional, Häberle, L, additional, Hein, A, additional, Jud, S M, additional, Lux, M P, additional, Hack, C C, additional, Emons, J, additional, Heindl, F, additional, Nabieva, N, additional, Löhberg, C R, additional, Schulz-Wendtland, R, additional, Hartmann, A, additional, Beckmann, M W, additional, Fasching, P A, additional, and Gaß, P, additional

Published
2020
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32. Disialogangliosids GD2 beim Mammakarzinom und dessen Einfluss auf die Prognose

Author

Erber, R, additional, Kailayangiri, S, additional, Hübner, H, additional, Rübner, M, additional, Hartmann, A, additional, Häberle, L, additional, Meyer, J, additional, Mackensen, A, additional, Landgraf, L, additional, Schulz-Wendtland, R, additional, Beckmann, M W, additional, Fasching, P A, additional, Farwick, N, additional, Rössig, C, additional, and Gaß, P, additional

Published
2020
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36. RANKL and OPG and their influence on breast volume changes during pregnancy in healthy women

Author

Wunderle, M, additional, Rübner, M, additional, Häberle, L, additional, Schwenke, E, additional, Hack, CC, additional, Bayer, CM, additional, Koch, MC, additional, Schwitulla, J, additional, Schulz-Wendtland, R, additional, Kozieradzki, I, additional, Lux, MP, additional, Beckmann, MW, additional, Jud, SM, additional, Penninger, JM, additional, Schneider, MO, additional, and Fasching, PA, additional

Published
2019
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37. Abstract GS5-03: Lifestyle Intervention and Effect on Disease-free Survival in Early Breast Cancer Pts: Interim Analysis from the Randomized SUCCESS C Study

Author

Janni, W, primary, Rack, BK, additional, Friedl, TW, additional, Müller, V, additional, Lorenz, R, additional, Rezai, M, additional, Tesch, H, additional, Heinrich, G, additional, Andergassen, U, additional, Harbeck, N, additional, Schochter, F, additional, De Gregorio, A, additional, Tzschaschel, M, additional, Huober, J, additional, Hepp, P, additional, Fehm, TN, additional, Schneeweiss, A, additional, Lichtenegger, W, additional, Blohmer, J, additional, Hauner, D, additional, Beckmann, MW, additional, Häberle, L, additional, Fasching, PA, additional, and Hauner, H, additional

Published
2019
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38. Abstract P1-13-01: Final results of the ASG1-3 study, a randomized phase III study comparing a standard dose chemotherapy with epirubicin/cyclophosphamide and paclitaxel with a dose dense regimen with epirubicin and paclitaxel

Author

Fasching, PA, primary, Eggemann, H, additional, Krocker, J, additional, Häberle, L, additional, Volz, B, additional, Kleine-Tebbe, A, additional, Blohmer, J-U, additional, Kittel, K, additional, Hufnagel, M, additional, Janni, W, additional, Emons, G, additional, Simon, E, additional, Köhler, U, additional, Thomssen, C, additional, Kohls, A, additional, Beckmann, MW, additional, Hielscher, C, additional, Krabisch, P, additional, Zeiser, T, additional, Brodkorb, T, additional, Baier, F, additional, Nabieva, N, additional, Kellner, S, additional, Untch, M, additional, Stadie, S, additional, Budner, M, additional, Breitbach, G-P, additional, Keller, M, additional, Stickeler, E, additional, Kühn, T, additional, Tolkmitt, M, additional, Belau, AK, additional, Schmidt, M, additional, Ulm, K, additional, and Kümmel, S, additional

Published
2019
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39. Cancers in Patients with Endometriosis

Author

Blum, S, additional, Häberle, L, additional, Tchartchian, G, additional, Schippert, C, additional, Fehm, T, additional, Hartung, CP, additional, Widschwendter, P, additional, Reicke, S, additional, Füger, T, additional, Germeyer, A, additional, Oppelt, P, additional, Lange, J, additional, Fleisch, M, additional, Renner, SP, additional, Hein, A, additional, Fasching, PA, additional, Beckmann, MW, additional, and Burghaus, S, additional

Published
2018
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40. TILGen: A Program to Investigate Immune Targets in Breast Cancer Patients – First Results on the Influence of Tumor-Infiltrating Lymphocytes

Author

Huebner, H, additional, Erber, R, additional, Hein, A, additional, Lux, MP, additional, Jud, S, additional, Kremer, AN, additional, Kranich, H, additional, Mackensen, A, additional, Häberle, L, additional, Hack, C, additional, Rauh, C, additional, Wunderle, M, additional, Gaß, P, additional, Rabizadeh, S, additional, Brandl, AL, additional, Langemann, H, additional, Volz, B, additional, Nabieva, N, additional, Schulz-Wendtland, R, additional, Dudziak, D, additional, Beckmann, MW, additional, Hartmann, A, additional, Fasching, PA, additional, and Rübner, M, additional

Published
2018
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41. A prediction model for pathological complete response after neoadjuvant chemotherapy of HER2-negative breast cancer patients

Author

Häberle, L., primary, Erber, R., additional, Gaß, P., additional, Hein, A., additional, Jud, S.M., additional, Langemann, H., additional, Rauh, C., additional, Hack, C.C., additional, Schulz-Wendtland, R., additional, Hartmann, A., additional, Beckmann, M.W., additional, Lux, M.P., additional, and Fasching, P.A., additional

Published
2018
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44. TILGen: Eine Studie zur Untersuchung immunonkologischer Marker für die Behandlung des Mammakarzinoms – Erste Ergebnisse zum Einfluss Tumor-infiltrierender Lymphozyten

Author

Huebner, H, additional, Erber, R, additional, Würfel, F, additional, Hein, A, additional, Lux, MP, additional, Jud, S, additional, Kremer, A, additional, Kranich, H, additional, Mackensen, A, additional, Häberle, L, additional, Hack, CC, additional, Rauh, C, additional, Wunderle, M, additional, Gaß, P, additional, Rabizadeh, S, additional, Brandl, AL, additional, Langemann, H, additional, Volz, B, additional, Nabieva, N, additional, Schulz-Wendtland, R, additional, Dudziak, D, additional, Beckmann, MW, additional, Hartmann, A, additional, Fasching, PA, additional, and Rübner, M, additional

Published
2018
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45. Nachweis von zirkulierenden Tumorzellen bei Patientinnen mit frühem Brustkrebs fünf Jahre nach adjuvanter Chemotherapie und späte Rezidive – Ergebnisse der SUCCESS A Studie

Author

Schochter, F, additional, Rack, B, additional, Fasching, PA, additional, Häberle, L, additional, Tesch, H, additional, Lorenz, R, additional, Tzschaschel, M, additional, De Gregorio, A, additional, Fehm, T, additional, Müller, V, additional, Schneeweiss, A, additional, Lichtenegger, W, additional, Beckmann, MW, additional, Scholz, C, additional, Pantel, K, additional, Janni, W, additional, and Friedl, TWP, additional

Published
2018
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46. Gemeinsame Risiko-Pathways von Endometriose und Ovarialkarzinom

Author

Burghaus, S, additional, Häberle, L, additional, Rübner, M, additional, Büchner, K, additional, Blum, S, additional, Engel, A, additional, Ekici, AB, additional, Hartmann, A, additional, Hein, A, additional, Renner, SP, additional, Beckmann, MW, additional, and Fasching, PA, additional

Published
2018
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48. Genetic variants in FCGR2A and FCGR3A and disease-free survival in patients with HER2 positive breast cancer treated with trastuzumab in the SUCCESS A trial

Author

Wunderle, M, additional, Hein, A, additional, Rack, B, additional, Häberle, L, additional, Li, L, additional, Ekici, AB, additional, Reis, A, additional, Lux, MP, additional, Cunningham, JM, additional, Rübner, M, additional, Schneeweiss, A, additional, Tesch, H, additional, Blohmer, JU, additional, Fehm, T, additional, Heinrich, G, additional, Rezai, M, additional, Beckmann, MW, additional, Janni, W, additional, Weinshilboum, RM, additional, Wang, L, additional, and Fasching, PA, additional

Published
2018
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49. Abstract P6-13-01: Withdrawn

Author

Janni, WJ, primary, Harbeck, N, additional, Rack, B, additional, Gluz, O, additional, Schneeweiss, A, additional, Kates, R, additional, Fehm, T, additional, Kreipe, H, additional, Kümmel, S, additional, Würstlein, R, additional, Hartkopf, A, additional, Clemens, M, additional, Reimer, T, additional, Friedl, T, additional, Häberle, L, additional, Fasching, P, additional, and Nitz, U, additional

Published
2018
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50. Genetic Breast Cancer Susceptibility Variants and Prognosis in the Prospectively Randomized SUCCESS A Study

Author

Hein, A., additional, Rack, B., additional, Li, L., additional, Ekici, A., additional, Reis, A., additional, Lux, M., additional, Cunningham, J., additional, Rübner, M., additional, Fridley, B., additional, Schneeweiss, A., additional, Tesch, H., additional, Lichtenegger, W., additional, Fehm, T., additional, Heinrich, G., additional, Rezai, M., additional, Beckmann, M, additional, Janni, W., additional, Weinshilboum, R., additional, Wang, L., additional, Fasching, P., additional, and Häberle, L., additional

Published
2017
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