25 results on '"Guzmán-Parra J"'
Search Results
2. Art therapy in museums for mental health recovery: pilot study.
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Goodman-Casanova, J., Cuesta-Lozano, D., Guzmán-Parra, J., Durán-Jiménez, F., García-Gallardo, M., and Mayoral, F.
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ART therapy ,EXPRESSIVE arts therapy ,MENTAL health ,ART museums ,MENTAL illness - Abstract
Introduction: Mental health recovery is a multidimensional phenomenon which requires of a participatory transformative experiential approach. This is the pilot study of the non-randomized trial RecuperArte (Ethics approval: 0385-N-19, Clinicaltrials.gov: NCT03985904) to demonstrate the effectiveness of art therapy (NIC 4330) in museums in mental health recovery. Objectives: Change from baseline global functioning, personal resilience and social support at 3 months. Methods: Design: Prospective longitudinal non-randomized intervention without comparison. Settings: The Mental Health Rehabilitation Unit of the Andalusian Health Service (Spain) in collaboration with the Association of family members and people with mental disease (AFENES) and the Carmen Thyssen Museum Participants: Inclusion criteria: adults, ICD-10 F20-29 diagnosis or F with psychotic history and written consent. Exclusion criteria: Score in GAF <50. Statistical analysis: The results were analyzed using the Student's t-test. The sample size was n = 8. Results: Out of the 8 participants, 6 were men and 2 women, the mean age was 44.75 years (SD 11.10663) and the most common ICD-10 diagnosis was F20-29 (71.43%). All participants were single, predominantly resided with their family of origin (62.5%) and were pensioners (87.5%). Participants GAF ranged 71-100 and remained stable at follow-up except for one participant who dropped-out scoring 41-50. The mean of differences was 0.1266664 in personal resilience and 5 in perceived social support. Conclusions: The limited sample size did not provide statistically significant data but served as a proof of concept for the trial which will cover a larger population n = 127 and will have a comparison group. [ABSTRACT FROM AUTHOR]
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- 2020
3. Impulsivity, decision-making and risk behavior in bipolar disorder and major depression in bipolar multiplex families.
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Ramírez-Martín, A., Guzmán-Parra, J., Streit, F., Witt, S., Frank, J., Sirignano, L., Andlauer, T., Nöthen, M., Forstner, A., De Diego-Otero, Y., Mayoral, F., Rietschell, M., and Moreno-Küstner, B.
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BEHAVIOR disorders , *BIPOLAR disorder , *AT-risk behavior , *MENTAL depression , *RESPONSE inhibition - Abstract
Introduction: It is not clear whether in families with a marked genetic risk for bipolar disorder (BD) there are impairments in impulsivity, risk behavior and decision making in BD and major depressive disorder (MDD). Objectives: To analyze differences in impulsivity, decision making and risk behavior in bipolar multiplex family members diagnosed with BD, MDD and a healthy control group (HC). Methods: A sample of 8 bipolar multiplex families of an ongoing study (ABIF) was used. A group with a diagnosis of BD (N =31), another with a diagnosis of MDD (N = 26) and finally a HC group (N = 31) from the families and the community were compared. The Stop Signal Task and the Cambridge Gambling Task from the CANTAB battery were used. Mixed logistic regression adjusted by age and gender was carried out. Family structure was included as a random effect using a genetic relationship matrix. The analysis was carried out in R using the function relmatLmer of the package lme4qtl4. Results: There were significant differences between BD and HC, with higher delay aversion (p = 0.032) in BD and marginally significant results with worse response inhibition (p = 0.057) and decision making (p = 0.057) in BD. No differences were found in risk behavior (p = 0.181). There were no significant differences between BD and MDD and between MDD and HC in any variable. Conclusions: In bipolar multiplex families specific deficits were found in impulsivity in individuals with BD. Larger studies are needed to detect smaller effects. [ABSTRACT FROM AUTHOR]
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- 2020
4. Gender differences and risk of readmission in hospitalizations with a diagnosis of psychotic spectrum disorders.
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Carbonell-Aranda V, Herrera-Imbroda J, Moreno-Küstner B, and Guzmán-Parra J
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- Humans, Female, Male, Adult, Sex Factors, Risk Factors, Middle Aged, Prognosis, Young Adult, Patient Readmission statistics & numerical data, Psychotic Disorders diagnosis, Psychotic Disorders epidemiology, Hospitalization statistics & numerical data
- Abstract
Background: Gender differences in psychosis are a topic that has been studied considering different aspects. Although some available evidence would point to a possible better prognosis in women, this claim is far from conclusively established., Methods: We propose an analysis of gender differences in the risk of readmission to an acute hospitalization unit, an indicator related to prognosis., Results and Conclusions: We found that although the risk of readmission at 1 year is lower in women, this seems to be explained by other confounding factors., (© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Austria, part of Springer Nature.)
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- 2024
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5. Post-COVID job Stressors and Their Predictive Role on Mental Health: A Cross-Sectional Analysis Between Physicians and Nurses.
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Fernández-Martínez S, Armas-Landaeta C, Pérez-Aranda A, Guzmán-Parra J, Monreal-Bartolomé A, Carbonell-Aranda V, García-Campayo J, and López-Del-Hoyo Y
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Introduction: Health care providers face heightened stress and increased rates of anxiety and depression post-COVID-19. The pandemic, officially declared over in May 2023, continues to impact their wellbeing significantly, with ongoing mental health monitoring and tailored interventions crucial for support., Objectives: The aim of this study was to describe the frequency of job stressors in a sample of Spanish health care providers post-COVID and to explore potential differences between physicians and nurses, hypothesizing that while both professional categories could experience similar job stressors, some of them could have a differential impact on the mental health of each subgroup., Methods: This cross-sectional substudy is part of the MINDxYOU project. The data were collected from 191 health care providers from two regions in Spain. Participants completed the UNIPSICO test battery, used to assess job stressors, and questionnaires to evaluate perceived stress, depressive symptomatology, anxiety, and resilience. Descriptive analyses, bivariate correlations, and linear regression models were performed to compare the two professions that were the most representative of our sample: physicians (n = 82) and nurses (n = 54)., Results: The most frequent job stressors were workload, lack of positive feedback, and inequity in social interactions. Physicians reported worse outcomes in terms of workload, autonomy, role conflicts, inequity in social interactions, and work-family balance compared to nurses. Mobbing, despite not being very frequent, significantly predicted different mental health outcomes for both physicians and nurses. Inequity in social interactions and job satisfaction were significant predictors of physicians' mental health, while role ambiguity, interpersonal conflicts, and career turnover intentions predicted nurses' mental health., Conclusion: As hypothesized, our findings highlight that certain job stressors (i.e., inequity in social interactions, conflicts in the workplace) might be affecting physicians' and nurses' mental health differently. Therefore, effective strategies addressing each subgroup's specific stressors would be necessary to prevent the development of burnout syndrome and other serious mental health conditions associated with occupational stress. These strategies would imply organizational changes in most cases., Competing Interests: The authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article., (© The Author(s) 2024.)
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- 2024
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6. Pharmacotherapeutic value of inflammatory and neurotrophic biomarkers in bipolar disorder: A systematic review.
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Ruiz-Sastre P, Gómez-Sánchez-Lafuente C, Martín-Martín J, Herrera-Imbroda J, Mayoral-Cleries F, Santos-Amaya I, Rodríguez de Fonseca F, Guzmán-Parra J, Rivera P, and Suárez J
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- Humans, Antidepressive Agents therapeutic use, Antipsychotic Agents therapeutic use, Inflammation drug therapy, Inflammation blood, Nerve Growth Factors blood, Antimanic Agents therapeutic use, Bipolar Disorder drug therapy, Bipolar Disorder blood, Biomarkers blood
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Background: The various pharmacological interventions, ranging from mood stabilizers and antipsychotics to antidepressants, reflect the diff/iculty of treating depressive/manic symptomatology of bipolar disorder (BD). Among a broad range of mechanisms implicated, immune dysregulation may contribute to the increased inflammation that influences the course of BD. Inflammatory, neurotrophic and oxidative stress factors may be identified as promising peripheral biomarkers in brain functioning, perhaps serving as predictors of an effective response to treatment for BD. The present systematic review aimed to examine the evidence supporting the pharmacotherapeutic value of inflammatory and neurotrophic biomarkers in BD., Methods: PubMed, PsychINFO, Scopus and Web of Science were searched from inception to May 2024 by two independent reviewers. A total of 40 studies with 3371 patients with diagnosis and intervention of BD were selected., Results: Inconsistencies in the effects of pharmacological treatments on the connection between the expected anti-inflammatory response and symptomatologic improvement were identified. Mood stabilizers (lithium), antipsychotics (quetiapine), antidepressants (ketamine) or their combination were described to increase both pro-inflammatory (TNFα, IL-6) and anti-inflammatory (IL-4, IL-8) factors. Other medications, such as memantine and dextromethorphan, autoimmune (infliximab) non-steroidal anti-inflammatory (aspirin, celecoxib) drugs, antidiabetics (pioglitazone), and even dietary supplementation (omega-3), or their combination, clearly decrease inflammatory factors (TNFα, IL-6, IL-1β, C-reactive protein) and/or increase the neurotrophic factor BDNF in BD patients., Conclusion: Inflammation in BD requires further investigation to understand the underlying immunologic mechanism, to identify predictors of treatment response, and to make informed decisions about the use and development of more effective pharmacological interventions for BD., Competing Interests: Declaration of competing interest None of the submitted material has been published or is under consideration elsewhere. All the authors have approved the manuscript and declare no conflict of interest., (Copyright © 2024 The Authors. Published by Elsevier Inc. All rights reserved.)
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- 2024
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7. Impulsivity, decision-making, and risk behavior in bipolar disorder and major depression from bipolar multiplex families.
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Ramírez-Martín A, Sirignano L, Streit F, Foo JC, Forstner AJ, Frank J, Nöthen MM, Strohmaier J, Witt SH, Mayoral-Cleries F, Moreno-Küstner B, Rietschel M, and Guzmán-Parra J
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Objectives: Bipolar disorder (BD) and major depressive disorder (MDD) are characterized by specific alterations of mood. In both disorders, alterations in cognitive domains such as impulsivity, decision-making, and risk-taking have been reported. Identification of similarities and differences of these domains in BD and MDD could give further insight into their etiology. The present study assessed impulsivity, decision-making, and risk-taking behavior in BD and MDD patients from bipolar multiplex families., Methods: Eighty-two participants (BD type I, n = 25; MDD, n = 26; healthy relatives (HR), n = 17; and healthy controls (HC), n = 14) underwent diagnostic interviews and selected tests of a cognitive battery assessing neurocognitive performance across multiple subdomains including impulsivity (response inhibition and delay aversion), decision-making, and risk behavior. Generalized estimating equations (GEEs) were used to analyze whether the groups differed in the respective cognitive domains., Results: Participants with BD and MDD showed higher impulsivity levels compared to HC; this difference was more pronounced in BD participants. BD participants also showed lower inhibitory control than MDD participants. Overall, suboptimal decision-making was associated with both mood disorders (BD and MDD). In risk-taking behavior, no significant impairment was found in any group., Limitations: As sample size was limited, it is possible that differences between BD and MDD may have escaped detection due to lack of statistical power., Conclusions: Our findings show that alterations of cognitive domains-while present in both disorders-are differently associated with BD and MDD. This underscores the importance of assessing such domains in addition to mere diagnosis of mood disorders., (© 2024 The Authors. Brain and Behavior published by Wiley Periodicals LLC.)
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- 2023
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8. Suicidal behavior in persons attended in out-of-hospital emergency services in Spain.
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Ramos-Martín J, Gómez Sánchez-Lafuente C, Martínez-García AI, Castillo-Jiménez P, Guzmán-Parra J, and Moreno-Küstner B
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Background: The aims of this study were to describe the use of health services by patients attended for suicidal behavior by out-of-hospital emergency services and to identify the variables associated with the repetition of this behavior in Spain., Methods: An analytical, observational, retrospective study was carried out. A total of 554 patients attended by the mobile teams of the Primary Care Emergency (mt-PCES) of the Malaga Health District (Spain), after being coordinated by the 061 Emergency Coordination Center (ECC) were analyzed., Results: Of the total, 61.9% of the patients were women and the mean age was 43.5 years. Ninety-six percent ( N = 532) of the patients attended by mt-PCES were transferred to hospital emergency services. Regarding clinical decision, of those transferred 436 persons (82%) were discharged home. Of the total sample 25.5% ( N = 141) were referred to primary care, while 69% ( N = 382) were referred to outpatient mental health care. Regarding follow up in the 6 months after being seen by emergency services, among those referred to a mental health facility, 64.4% ( N = 246) attended the follow-up appointment while out of the total sample only 50.5% ( N = 280) attended a follow-up appointment with an outpatient mental health service. Finally, it should be noted that 23.3% presented a relapse of suicidal behavior in the 6 months following index episode. The variables associated with repetition of suicidal behavior were older age, greater number of previous suicide attempts and having any contact with mental health services in the following 6 months., Conclusion: We believe that selective suicide prevention initiatives should be designed to target the population at risk of suicide, especially those receiving both out-of-hospital and in-hospital emergency services., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2023 Ramos-Martín, Gómez Sánchez-Lafuente, Martínez-García, Castillo-Jiménez, Guzmán-Parra and Moreno-Küstner.)
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- 2023
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9. Attitudes about Mechanical Restraint Use in Mental Health Hospitalization Services: A Spanish Survey.
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Aguilera-Serrano C, Goodman-Casanova JM, Bordallo-Aragón A, García-Sánchez JA, Mayoral-Cleries F, and Guzmán-Parra J
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The aim of this study was to analyze the attitudes of professionals in Mental Health Services throughout Spain who are directly or indirectly involved in the use of mechanical restraint and the barriers perceived to reduce its use. The study involved an online anonymous survey using Google Forms completed by Spanish mental health professionals working with service users; the survey assessed their involvement in and general attitudes and beliefs towards mechanical restraint. The survey was completed by 225 participants. Only 13.30% of the participants considered that mechanical restraint use was never necessary to guarantee the safety of users/staff in dangerous situations. Poor staff training (38.0%) and a lack of resources/staff (34.7%) were the most frequent barriers identified for the reduction of mechanical restraint. In the multivariate analysis, participation in learning programs to prevent the use of mechanical restraint was associated with lower acceptance of the use of mechanical restraint, but the result was barely significant ( p = 0.050). A high percentage of mental health staff still consider mechanical restraint use necessary for safety reasons. According to the results, the participants perceived that more staff and resources and better training could reduce the use of mechanical restraint in Mental Health Hospitalization Services.
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- 2023
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10. Risk of psychiatric readmission in the homeless population: A 10-year follow-up study.
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Herrera-Imbroda J, Guzmán-Parra J, Bordallo-Aragón A, Moreno-Küstner B, and Mayoral-Cleríes F
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Homelessness continues to be a major social and clinical problem. The homeless population has a higher burden of disease that includes psychiatric disorders. In addition, they have a lower use of ambulatory health services and a higher use of acute care. Few investigations analyze the use of services of this population group in the long term. We analyzed the risk of psychiatric readmission of homeless individuals through survival analysis. All admissions to a mental health hospitalization unit in the city of Malaga, Spain, from 1999 to 2005, have been analyzed. Three analyses were carried out: two intermediate analyses at 30 days and 1 year after starting follow-up; and one final analysis at 10 years. In all cases, the event was readmission to the hospitalization unit. The adjusted Hazard Ratio at 30 days, 1-year, and 10-year follow-ups were 1.387 ( p = 0.027), 1.015 ( p = 0.890), and 0.826 ( p = 0.043), respectively. We have found an increased risk of readmission for the homeless population at 30 days and a decreased risk of readmission at 10 years. We hypothesize that this lower risk of long-term readmission may be due to the high mobility of the homeless population, its low degree of adherence to long-term mental health services, and its high mortality rate. We suggest that time-critical intervention programs in the short term could decrease the high rate of early readmission of the homeless population, and long-term interventions could link them with services and avoid its dispersion and abandonment., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2023 Herrera-Imbroda, Guzmán-Parra, Bordallo-Aragón, Moreno-Küstner and Mayoral-Cleríes.)
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- 2023
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11. Factors associated with prolonged episodes of mechanical restraint in mental health hospitalization units in Andalusia.
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Guzmán-Parra J, Aguilera-Serrano C, Huizing E, Bono Del Trigo A, Villagrán JM, Hurtado Melero V, García-Sanchez JA, and Mayoral-Cleries F
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- Male, Humans, Retrospective Studies, Restraint, Physical, Hospitalization, Mental Health, Mental Disorders therapy, Mental Disorders psychology
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WHAT IS KNOWN ON THE SUBJECT?: Risk factors associated with prolonged episodes of mechanical restraint and other coercive measures are understudied. There have been no studies of this phenomenon in the context of the Andalusian public health system. Knowledge about factors associated with prolonged episodes is essential to increase the understanding of this phenomenon and develop strategies to reduce its occurrence. WHAT DOES THIS PAPER ADD TO EXISTING KNOWLEDGE?: In Andalusia, prolonged restraint is still frequent and varies depending on the unit. It is associated with less time since admission, male gender, diagnosis, reason for restraint and the shift on which it was initiated. WHAT ARE THE IMPLICATIONS FOR PRACTICE?: Interventions at the level of the units could be necessary to prevent prolonged episodes of mechanical restraint. The results suggest the need for stricter control during the shifts on which restraint starts, especially in the first days after the patient's admission. Preventive risk assessment considering clinical and sociodemographic risk factors could help to reduce prolonged restraint. ABSTRACT: Introduction Factors associated with prolonged episodes of mechanical restraint and other coercive interventions are not clearly established and have been not studied in Andalusia (Spain). Aim To study factors associated with prolonged episodes of mechanical restraint. Method We analysed retrospectively episodes of mechanical restraint (N = 6267, prolonged episode >9.5 hours) in all public mental health hospitalization units (N = 20, 535 beds) that offer health coverage for the autonomous community of Andalusia. The data came from clinical records. A multivariable mixed logistic regression was used. Results In Andalusia, prolonged restraint is still frequent and varies depending on the unit. It is associated with less time since admission, male gender, diagnosis, reason for restraint and the shift on which it was initiated. Discussion The results provide evidence that prolonged episodes largely depend on the unit where they occur and that stricter control and regulation are necessary to prevent prolonged episodes. Implications for practice Interventions at the level of the unit are necessary. Stricter control in the shifts during which there is more risk of prolonged restraint may be necessary, especially in the first days following admission., (© 2022 John Wiley & Sons Ltd.)
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- 2022
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12. Clinical Value of Inflammatory and Neurotrophic Biomarkers in Bipolar Disorder: A Systematic Review and Meta-Analysis.
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Vega-Núñez A, Gómez-Sánchez-Lafuente C, Mayoral-Cleries F, Bordallo A, Rodríguez de Fonseca F, Suárez J, and Guzmán-Parra J
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Bipolar disorder (BD) is a multifactorial chronic psychiatric disease highly defined by genetic, clinical, environmental and social risk factors. The present systematic review and meta-analysis aimed to examine the relationship between inflammatory and neurotrophic factors and clinical, social and environmental factors involved in the development and the characterization of BD. Web of Science, PubMed, PsycINFO, Scopus and Science Direct were searched by two independent reviewers. The systematic review was registered in PROSPERO (CRD42020180626). A total of 51 studies with 4547 patients with a diagnosis of BD were selected for systematic review. Among them, 18 articles were included for meta-analysis. The study found some evidence of associations between BDNF and/or inflammatory factors and different stressors and functional and cognitive impairment, but limitations prevented firm conclusions. The main finding of the meta-analysis was a negative correlation between circulating levels of BDNF and depression severity score (standardized mean difference = -0.22, Confidence Interval 95% = -0.38, -0.05, p = 0.01). Evidence indicates that BDNF has a role in the depressive component of BD. However, the poor consistency found for other inflammatory mediators clearly indicates that highly controlled studies are needed to identity precise biomarkers of this disorder.
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- 2022
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13. EEG abnormalities and clinical phenotypes in pre-school children with autism spectrum disorder.
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Romero-González M, Navas-Sánchez P, Marín-Gámez E, Barbancho-Fernández MA, Fernández-Sánchez VE, Lara-Muñoz JP, and Guzmán-Parra J
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- Child, Child, Preschool, Cross-Sectional Studies, Electroencephalography methods, Executive Function, Humans, Phenotype, Autism Spectrum Disorder diagnosis
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Background: Abnormalities on electroencephalography (EEG) results have been reported in a high percentage of children with Autism Spectrum Disorder (ASD). The purpose of this study was to explore the prevalence of EEG abnormalities in a clinical population of pre-school children with Autism Spectrum Disorder and the differences in terms of the following phenotypic characteristics: adaptive behavior, executive functioning, severity of Autism Spectrum Disorder core symptoms, and comorbidity symptoms., Methods: A cross-sectional analysis of 69 children who attended the Autism Spectrum Disorder early diagnosis program with electroencephalography and clinical diagnosis was performed. A battery of questionnaires was also made to parents to evaluate emotions, behavior, and functional skills for daily living., Results: Out of 69 pre-school children with Autism Spectrum Disorder, twenty nine (42%) had abnormalities in electroencephalography results. The group with abnormal epileptiform electroencephalography exhibited more impairment in executive functioning and social-relationship coexisting symptoms., Conclusions: The presence of an abnormal epileptiform electroencephalography in pre-school children with ASD already suggests a worse development in clinical features., (Copyright © 2022 The Author(s). Published by Elsevier Inc. All rights reserved.)
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- 2022
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14. Iconic Therapy for the reduction of borderline personality disorder symptoms among suicidal youth: a preliminary study.
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Hurtado-Santiago S, Guzmán-Parra J, Mayoral F, and Bersabé RM
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- Adolescent, Humans, Suicidal Ideation, Borderline Personality Disorder psychology, Borderline Personality Disorder therapy, Self-Injurious Behavior psychology, Self-Injurious Behavior therapy
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Background: Iconic therapy (IT) is a new therapy that uses images to teach skills with the aim of improving the symptoms of borderline personality disorder. Preliminary results are promising, and there is indication that IT may be effective. The purpose of this preliminary study was to test the effectiveness of IT compared to a psychological supportive intervention (SI)., Methods: The study was carried out at the University Regional Hospital of Malaga. Young patients (N = 40; 15-30 years) with suicidal or parasuicidal behavior and borderline personality traits were randomized into IT (N = 20) or SI (N = 20). The main outcome variable was a change in the symptoms of borderline personality disorder (BSL-23) at the end of treatment. The secondary outcome variables were suicidal ideation and behavior, self-harm, the need for medication, the number of visits to mental health professionals, maladaptive behavior, satisfaction with therapy and perceived improvement, both at the end of the intensive treatment and at the 12-month follow-up., Results: As expected, the two therapies produced a reduction in BPD symptoms at 10 weeks post-treatment and at the 12-month follow-up. Contrary to expectation, there were no statistically significant differences in the effectiveness of the two therapies (p > 0.05). However, at the 12-month follow-up, the effect sizes for the difference between the effectiveness of the two therapy groups on BSL-23 scores (d = 0.33) and on maladjustment to daily life (d = 0.39) was found to exceed the commonly used convention for a small effect (d = 0.20). Besides, participants in the IT group showed greater satisfaction with therapy than those who received SI. The mean difference between groups was statistically significant after the 10-week treatment period (p < .01), with a large effect size (d = 1.11). Nevertheless, this difference was not maintained at the 12-month follow-up (p > .05), although the effect size for this analysis (d = 0.34) was found to exceed a small effect., Conclusions: This preliminary study did not find a statistically significant difference in the effectiveness of the two therapies, probably due to the small sample of participants, but there are some indicators (effect sizes) suggesting that perhaps IT may be superior for reducing BPD symptoms and maladjustment in daily life. Future studies with larger samples and comparisons with established treatments for borderline personality disorder are necessary to confirm that IT effects are significant and persistent in the long term., Trial Registration: ClinicalTrials.gov identifier: NCT03011190 . First posted 05/01/2017. Last update posted 15/05/2018., (© 2022. The Author(s).)
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- 2022
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15. Effectiveness of eHealth-Based Psychological Interventions for Depression Treatment in Patients With Type 1 or Type 2 Diabetes Mellitus: A Systematic Review.
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Varela-Moreno E, Carreira Soler M, Guzmán-Parra J, Jódar-Sánchez F, Mayoral-Cleries F, and Anarte-Ortíz MT
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Background: Comorbidity between diabetes mellitus and depression is highly prevalent. The risk of depression in a person with diabetes is approximately twice that of a person without this disease. Depression has a major impact on patient well-being and control of diabetes. However, despite the availability of effective and specific therapeutic interventions for the treatment of depression in people with diabetes, 50% of patients do not receive psychological treatment due to insufficient and difficult accessibility to psychological therapies in health systems. The use of information and communication technologies (ICTs) has therefore been proposed as a useful tool for the delivery of psychological interventions, but it continues to be a field in which scientific evidence is recent and controversial. This systematic review aims to update the available information on the efficacy of psychological interventions delivered through ICTs to improve depressive symptomatology in patients with diabetes., Methods: A systematic review of the literature was performed following the PRISMA guidelines and using MEDLINE, Embase, PubMed, Web of Science, PsycINFO, Scopus, and Cochrane Library databases to search for randomized clinical trials of eHealth treatments for patients with diabetes and comorbid depression from 1995 through 2020. In addition, studies related to follow-up appointments were identified. Inclusion criteria were as follows: (a) randomized clinical trials (RCTs); (b) patients with type 1 and type 2 diabetes; (c) adult population over 18 years of age; (d) presence of depressive symptomatology assessed with standardized instruments; (e) treatments for depression based on established psychotherapeutic techniques and principles; (f) delivered through eHealth technologies. We did not limit severity of depressive symptomatology, delivery setting or comparison group (treatment as usual or other treatment). Two coauthors independently reviewed the publications identified for inclusion and extracted data from the included studies. A third reviewer was involved to discuss discrepancies found. The PEDro scale was used to assess the quality of the RCTs. No meta-analysis of the results was performed. The protocol used for this review is available in PROSPERO (Reg; CRD42020180405)., Results: The initial search identified 427 relevant scientific publications. After removing duplicates and ineligible citations, a total of 201 articles were analyzed in full text. Ten articles met the criteria of this review and were included, obtaining very good scientific quality after evaluation with the PEDro scale. The main results show that the eHealth psychological intervention for depression in patients with diabetes showed beneficial effects both at the end of treatment and in the short (3 months) and long term (6 and 12 months) for the improvement of depressive symptomatology. The methodology used (type of diabetes, eHealth technology used, recruitment context, implementation and follow-up) was very heterogeneous. However, all studies were based on cognitive-behavioral tools and used standardized assessment instruments to evaluate depressive symptomatology or diagnosis of MDD. Glycemic control was assessed by glycosylated hemoglobin, but no benefits were found in improving glycemic control. Only four studies included psychoeducational content on diabetes and depression, but none used tools to improve or enhance adherence to medical prescriptions or diabetes self-care., Conclusions: ICT-based psychological interventions for the treatment of depression in people with diabetes appear to be effective in reducing depressive symptomatology but do not appear to provide significant results with regard to glycemic control. Nonetheless, the scientific evidence reported to date is still very limited and the methodology very diverse. In addition, no studies have implemented these systems in routine clinical practice, and no studies are available on the economic analysis of these interventions. Future research should focus on studying and including new tools to ensure improvements in diabetes outcomes and not only on psychological well-being in order to advance knowledge about these treatments. Economic evaluations should also be undertaken to analyze whether these treatment programs implemented using eHealth technologies are cost-effective., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2022 Varela-Moreno, Carreira Soler, Guzmán-Parra, Jódar-Sánchez, Mayoral-Cleries and Anarte-Ortíz.)
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- 2022
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16. [Relationship between parental stress and psychological distress and emotional and behavioural problems in pre-school children with autistic spectrum disorder].
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Romero-González M, Marín E, Guzmán-Parra J, Navas P, Aguilar JM, Lara JP, and Barbancho MÁ
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- Child, Child, Preschool, Humans, Quality of Life, Autism Spectrum Disorder epidemiology, Parents psychology, Problem Behavior, Psychological Distress
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Introduction: The Autistic Spectrum Disorders (ASD) are characterised by general deficits in social communication, stereotypes, and restricted interests. The ASD have a high prevalence of additional psychiatric disorders that make their daily functioning worse, and reduces the quality of life of them and their families., Material and Methods: In an effort to identify family environmental characteristics that may influence in the course of additional psychiatric disorders, this study has focused on the symptoms of parental stress and psychological distress as possible risk factors. A cross-section study was carried out on the relationship between the stress and psychological distress of the parents and its relationship with co-existing psychopathology in a population of pre-school children with ASD (2-6 years)., Results and Conclusions: High levels of stress and psychological distress of the parents arealready associated, since early childhood, with co-existing psychiatric symptoms, specifically with emotional and behavioural problems (p < 0.05). However, further longitudinal studies are needed for a better understanding of the causal relationship between these variables and their possible bidirectional relationship., (Copyright © 2020. Publicado por Elsevier España, S.L.U.)
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- 2021
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17. [Trends in psychiatric admissions in adults over 65 years old].
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Guzmán-Parra J, Flordelís-Lasierra E, Fabrega-Ruz J, Cuesta-Vargas A, Romero M, and Mayoral-Cleries F
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- Aged, Female, Humans, Male, Middle Aged, Retrospective Studies, Hospitalization trends, Hospitals, Psychiatric statistics & numerical data, Mental Disorders epidemiology
- Abstract
Background: The aim of this study was to analyse the trend in the percentages of elderly patients admitted to hospital for psychiatric reasons. An additional aim was to analyse the characteristics of the elderly population admitted to a psychiatric hospitalisation unit., Material an Methods: An analysis was made of the trends in the percentages of discharges in elderly population at the national level and in the Mental Health Hospitalisation Unit (MHHU) of the Regional University Hospital of Malaga for a period of at least 18years using segmented regression. For the study of the characteristics of the elderly population, all patients (N=5,925) and consecutive episodes of admission (N=15,418) were compared between 1999 and 2017 in the MHHU., Results: At the national level, there was an increase in hospital discharges in elderly patients with a significant mean annual percent change of 2.0%. In the study unit, the elderly population were more frequently female, involuntarily admitted, and had a longer hospital stay. They had been diagnosed more frequently with organic and depressive mental disorders, and less frequently with schizophrenia, substance use, and personality disorders., Conclusions: There was a growing trend in the percentage of elderly psychiatric patients admitted to hospitals during the study period. These results point to the increase in elderly psychiatric admissions and thus the need to adapt psychiatric units to the characteristics of this population., (Copyright © 2020 SEGG. Publicado por Elsevier España, S.L.U. All rights reserved.)
- Published
- 2020
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18. Factors Associated With High Use of Hospital Psychiatric Services in Málaga, Spain: Analysis of First Admissions.
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Guzmán-Parra J, Bordallo-Aragón A, Moreno-Küstner B, and Mayoral-Cleries F
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- Adolescent, Adult, Age Factors, Aged, Aged, 80 and over, Female, Humans, Length of Stay, Male, Mental Disorders therapy, Middle Aged, Retrospective Studies, Risk Factors, Spain, Young Adult, Hospitals, Psychiatric statistics & numerical data, Patient Acceptance of Health Care statistics & numerical data, Patient Admission statistics & numerical data
- Abstract
The early prediction of patients at risk may facilitate the efficient use of interventions that have been demonstrated to reduce readmissions. The aim of the study was to analyze variables during first admissions associated with further high use of an inpatient hospitalization psychiatric unit in Málaga, Spain. The risk of having three or more psychiatric admissions was analyzed in a sample of 1535 first-time admissions with multivariate Cox regression. In the multivariate model, the variables associated with the risk of high use were age at admission (p < 0.001), length of stay (p < 0.001), place of residence (p < 0.001), and previous history with mental health services (p < 0.001). The results suggest that there are several easily accessible characteristics at first admission that are potentially useful in detecting patients at risk.
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- 2020
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19. TV-based assistive integrated service to support European adults living with mild dementia or mild cognitive impairment (TV-AssistDem): study protocol for a multicentre randomized controlled trial.
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Goodman-Casanova JM, Guzmán-Parra J, Guerrero G, Vera E, Barnestein-Fonseca P, Cortellessa G, Fracasso F, Umbrico A, Cesta A, Toma D, Boghiu F, Dewarrat R, Triantafyllidou V, Tamburini E, Dionisio P, and Mayoral F
- Subjects
- Aged, Aged, 80 and over, Cognitive Behavioral Therapy methods, Cognitive Dysfunction epidemiology, Cognitive Dysfunction psychology, Dementia epidemiology, Dementia psychology, Europe epidemiology, Female, Follow-Up Studies, Humans, Male, Middle Aged, Quality of Life psychology, Romania epidemiology, Spain epidemiology, Caregivers psychology, Cognitive Dysfunction therapy, Delivery of Health Care, Integrated methods, Dementia therapy, Telemedicine methods, Television
- Abstract
Background: Mild cognitive impairment and mild dementia progressively compromise the ability of people to live independently and can have a negative impact on their quality of life. Within the current European Active and Assisted Living programme (AAL), project TV-AssistDem has been developed to deliver a TV-based platform service to support patients with mild cognitive impairment or mild dementia and provide relief to their caregivers. The application is intended to be used daily at home, mainly by the participants themselves, with the help of their informal caregivers. The aim of this study is to evaluate the effectiveness of TV-AssistDem to improve quality of life in people with mild cognitive impairment or mild dementia., Methods: This is a 12-month European multicentre randomized controlled trial which will be performed in two countries: Spain and Romania. Two hundred and forty older adults will be recruited using identical inclusion/exclusion criteria. The primary outcome will be the change from baseline of TV-AssistDem on patient quality of life at 12 months. The secondary outcomes will be the changes from baseline of: 1) informal caregiver quality of life, 2) informal caregiver burden, 3) patient treatment adherence, 4) patient treatment compliance, 5) patient functional status, and 6) healthcare cost-effectiveness at 12 months. Patients in the intervention group will have access to an interactive platform which offers remote assistive services through a device connected to the television. The core services of the platform are: 1) Calendar and reminders, 2) Health monitoring and data transmission to a health server and 3) Videoconference; service-oriented applications are: 4) Cognitive stimulation; 5) Reminiscences; and 6) Patient and caregiver healthcare education. The analysis will be made following an intention-to-treat procedure. Linear and Generalized Mixed Model analysis will be performed., Discussion: We hypothesize that the regular use of TV-AssistDem will result in an improvement in patient quality of life. The uniqueness of this home TV-based intervention lies on its widespread accessibility and its integrative approach to quality of life in people with mild cognitive impairment or mild dementia and their informal caregivers. However, several anticipated challenges will need to be faced: poor engagement and connectivity problems., Trial Registration: ClinicalTrials.gov Identifier NCT03653234 , Date of registration: 31 August 2018.
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- 2019
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20. Experience coercion, post-traumatic stress, and satisfaction with treatment associated with different coercive measures during psychiatric hospitalization.
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Guzmán-Parra J, Aguilera-Serrano C, García-Sanchez JA, García-Spínola E, Torres-Campos D, Villagrán JM, Moreno-Küstner B, and Mayoral-Cleries F
- Subjects
- Adult, Female, Hospitals, Psychiatric, Humans, Involuntary Treatment, Male, Mental Disorders psychology, Restraint, Physical psychology, Restraint, Physical statistics & numerical data, Stress Disorders, Post-Traumatic epidemiology, Coercion, Mental Disorders therapy, Patient Satisfaction, Stress Disorders, Post-Traumatic etiology
- Abstract
Coercive measures are frequently used in psychiatric hospitalization. However, there are few studies that analyse perceived coercion, post-traumatic stress, and subjective satisfaction with the hospitalization treatment associated with different types of coercive measures. The sample consisted of 111 patients admitted to two psychiatric units and divided into three groups based on the measure applied: involuntary medication (N = 41), mechanical restraint (N = 32), and combined measures (mechanical restraint and involuntary medication; N = 38). The outcome variables were perceived coercion evaluated with the Coercion Experience Scale (CES), post-traumatic stress evaluated with the Davidson Trauma Scale (DTS), and satisfaction with the treatment evaluated with the Client's Assessment of Treatment (CAT). The results found higher levels of perceived coercion associated with the use of mechanical restraint (P = 0.002) and combined measures (P < 0.001) in comparison with involuntary medication. Additionally, in relation to post-traumatic stress, mechanical restraint (P = 0.013) and combined measures (P = 0.004) were more stressful compared to involuntary medication. Finally, the use of combined measures was associated with lower satisfaction with inpatient psychiatric treatment compared to the use of involuntary medication (P = 0.006). The following recommendation would be consistent with the results found: if a patient does not specify a preference for some type of measure, involuntary medication could be used and mechanical restraint avoided, especially when used in combination with involuntary medication., (© 2018 Australian College of Mental Health Nurses Inc.)
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- 2019
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21. Epidemiology of Suicidal Behavior in Malaga (Spain): An Approach From the Prehospital Emergency Service.
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Moreno-Küstner B, Del Campo-Ávila J, Ruíz-Ibáñez A, Martínez-García AI, Castro-Zamudio S, Ramos-Jiménez G, and Guzmán-Parra J
- Abstract
Objective: This study aims to analyse the number and characteristics of calls made to the Málaga Prehospital Emergency Service (PES) for suicidal behavior based on sociodemographic, temporal, and health care variables. Method: This is a retrospective, descriptive study that records all calls made to the PES due to suicidal behavior (suicide attempts and completed suicides) in 2014. Sociodemographic variables (age, sex, and health district), variables related to the calls (time-slot, degree of sunlight, type of day, month, season of the year, prioritization, and number of resources mobilized) were extracted from these calls. The number of cases and percentages were presented for the qualitative variables. The rates per 100,000 were calculated by sex and health district and presented with the corresponding 95% confidence interval (CI). Results: Of the total valid calls to PES ( n = 181,824), 1,728 calls were made due to suicidal behavior (0.9%). The mean age was 43.21 (±18) years, 57.4% were women, and the rate was 112.1 per 100,000 inhabitants. The calls due to suicidal behavior were in the younger-middle age segment, in the time-slot between 16 and 23 h and during daylight hours, on bank holidays, in spring and summer in comparison with winter, and with a peak of calls in August. The majority of these calls were classified as undelayable emergencies and mobilized one health resource. Conclusions: Prehospital emergency services are the first contact to the sanitary services of persons or families with suicide attempts. This information should be a priority to offer a complete overview of the suicide behavior.
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- 2019
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22. Validation of a short version of the Coercion Experience Scale (CES-18): Psychometric characteristics in a Spanish sample.
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Aguilera-Serrano C, Guzmán-Parra J, Miranda-Paez J, García-Spínola E, Torres-Campos D, Villagrán-Moreno JM, Moreno-Küstner B, García-Sanchez JA, and Mayoral-Cleries F
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- Adult, Female, Humans, Male, Middle Aged, Psychometrics standards, Reproducibility of Results, Spain, Coercion, Hospitals, Psychiatric, Mental Disorders therapy, Psychometrics instrumentation
- Abstract
The Coercion Experience Scale (CES) is a questionnaire that evaluates the subjective experience of coercion during psychiatric hospitalization. This study aimed to assess a short version of the Coercion Experience Scale (CES-18) in a Spanish Sample (N = 114). Two authors independently selected the items, choosing those that could also be applied to the experience of coercion after the use of forced medication. Reliability was estimated using internal consistency coefficients. Internal validity was assessed by means of a factorial analysis based on the method of extraction of main components and using orthogonal rotation VARIMAX. Convergent and discriminatory validity was evaluated by correlation between the total score of the CES-18 with the original CES and a Visual Analogue Scale, The Davidson Trauma Scale and the Client Assessment of Treatment Scale. The CES-18 showed adequate internal consistency (Cronbach α = 0.940). Factor analysis resulted in a two-factor solution (Coercion and Humiliation and Fear) explaining 64.2% of the total variance. The correlation between the original CES and CES-18 was adequate (r = 0.968). The scores suggested good divergent and convergent validity. The Spanish language CES-18 demonstrated adequate psychometric proprieties in order to assess perceived coercion during psychiatric hospitalization., (Copyright © 2018 Elsevier B.V. All rights reserved.)
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- 2019
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23. Effectiveness of iconic therapy for the reduction of borderline personality disorder symptoms among suicidal youth: study protocol for a randomised controlled trial.
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Hurtado-Santiago S, Guzmán-Parra J, Bersabé RM, and Mayoral F
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- Adolescent, Adult, Behavior Therapy methods, Borderline Personality Disorder psychology, Female, Humans, Male, Outpatients, Research Design, Self-Injurious Behavior psychology, Suicidal Ideation, Treatment Outcome, Young Adult, Borderline Personality Disorder therapy, Psychotherapy methods, Psychotherapy, Group methods, Randomized Controlled Trials as Topic
- Abstract
Background: Borderline personality disorder (BPD) is associated with an intensive use of mental health services, even in the absence of a full diagnosis. Early symptom detection and intervention may help alleviate adverse long-term outcomes. Iconic Therapy is an innovative manual-driven psychotherapy that treats BPD symptoms in a specific and intensive manner. Preliminary results are promising and the indication is that Iconic Therapy may be effective in reducing BPD symptoms. The aim of this study is to assess how effective Iconic Therapy is compared to Structured Support Therapy in a real clinical setting., Methods/design: Our study will be a controlled 12-month pragmatic, two-armed RCT. A total of 72 young people (15 to 25 years old) with suicidal ideation/self-injuring behaviour and BPD traits and symptoms will participate in the study. The subjects will be randomised into two groups: Iconic Therapy or Structured Support Therapy. The participants will be assigned to either group on a 1:1 basis. Both the Iconic Therapy and the Structured Support Therapy programmes consist of 11 weekly sessions delivered by two trained psychologists in a group format of between 8 to 12 outpatients. The primary outcome will be measured by the change in symptom severity. Secondary outcomes include changes in suicidal ideation/ behaviour, non-suicidal self-injury, maladjustment to daily life and cost-effective analysis. The primary outcome will be a decrease in the severity of BPD symptoms as assessed by the Borderline Symptom List (BSL-23). For the clinical evaluation, three study assessments will take place: at baseline, after treatment and at 12-month follow-up. We hypothesise that patients attending the Iconic Therapy group will show a significantly higher reduction in symptoms than those in the Structured Support Therapy group. Data will be analysed using generalised estimating equation (GEE) models., Discussion: By responding to the need for briefer and more comprehensive therapies for BPD, we foresee that Iconic Therapy may provide an alternative treatment whose specific therapeutic principles, visually represented on icons, will overcome classical Structured Support Therapy at reducing BPD symptoms., Trial Registration: NCT03011190.
- Published
- 2018
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24. [Calls due to suicidal behaviour made to the prehospital, emergency department in Málaga: characteristics and associated factors].
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Jiménez-Hernández M, Castro-Zamudio S, Guzmán Parra J, Martínez-García AI, Guillén-Benítez C, and Moreno-Küstner B
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- Adolescent, Adult, Aged, Cross-Sectional Studies, Female, Humans, Male, Middle Aged, Retrospective Studies, Risk Factors, Spain, Suicidal Ideation, Suicide, Attempted statistics & numerical data, Young Adult, Emergency Service, Hospital statistics & numerical data, Suicide statistics & numerical data
- Abstract
Background: Suicidal behaviour (fatal and non-fatal) has become a serious public health problem in many countries. The aim of the study was to describe the differential characteristics of emergency calls due to suicidal behaviour made to the Emergency Coordinating Centre (CCUE) in the province of Málaga, in comparison with calls due to physical or psychiatric problems., Methods: Retrospective observational study of the calls recorded in the database of the Public Company for Emergency Health during one year. Multivariate logistic regression analyses were carried out including age, gender and the following variables related with the demand: hours of the day, type of day (working days or bank holidays), months of the year and trimesters, number of resources mobilized and types of resolution., Results: The analyses were carried out on 163,331 calls, of which 1,380 calls were due to suicidal behaviour (0.8%), 9,951 for psychiatric reasons (6.1%) and 152,000 for physical reasons (93%). The emergency calls for suicidal behaviour were mainly made by females, between 31-60 years, in the evening and at night, and required transfer to hospital and more than one mobilized resource. Calls due to completed suicide were more frequently made by older men. Calls due to suicidal tendencies predominated over those due to attempted or threatened suicide during the first trimester of the year, while the opposite was the case during the third trimester., Conclusions: The results indicated differential characteristics of suicide calls that are potentially relevant for prevention in spite of the limitations of the present study.
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- 2017
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25. Sociodemographic Characteristics and Psychological Adjustment Among Transsexuals in Spain.
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Guzmán-Parra J, Sánchez-Álvarez N, de Diego-Otero Y, Pérez-Costillas L, Esteva de Antonio I, Navais-Barranco M, Castro-Zamudio S, and Bergero-Miguel T
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- Adult, Female, Gender Identity, Humans, Male, Sexual Behavior psychology, Spain, Surveys and Questionnaires, Young Adult, Adaptation, Psychological, Transsexualism psychology
- Abstract
This study examined the sociodemographic characteristics and the psychological adjustment of transsexuals in Andalusia (Spain), and also analyzed the differences between female-to-male (FtM) and male-to-female (MtF) transsexuals. The sample included 197 transsexuals (101 MtF and 96 FtM) selected from those who visited the Transsexual and Gender Identity Unit at the Carlos Haya Hospital in Malaga between 2011 and 2012. Our analyses indicated that MtF transsexuals were more likely to have lower educational levels, live alone, have worked less frequently throughout their lifetime, and have engaged in prostitution. For FtM transsexuals, there were more frequent references to the mother's psychiatric history and more social avoidance and distress. Multivariate analysis showed that the number of personality dysfunctional traits and unemployment status were associated with depression in the entire sample. The following three conclusions can be made: there are significant differences between MtF and FtM transsexuals (mainly related to sociodemographic variables), depression was high in both groups, and a remarkable percentage of transsexuals have attempted suicide (22.8 %) or have had suicidal thoughts (52.3 %).
- Published
- 2016
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