347 results on '"Guttman, Mitchell"'
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2. The genomic and cellular basis of biosynthetic innovation in rove beetles
3. Denaturing purifications demonstrate that PRC2 and other widely reported chromatin proteins do not appear to bind directly to RNA in vivo
4. Long non-coding RNAs: definitions, functions, challenges and recommendations
5. Inhibition of SARS-CoV-2 growth in the lungs of mice by a peptide-conjugated morpholino oligomer targeting viral RNA
6. Xist nucleates local protein gradients to propagate silencing across the X chromosome
7. RNA promotes the formation of spatial compartments in the nucleus
8. A protein assembly mediates Xist localization and gene silencing
9. Regulatory non-coding RNAs: everything is possible, but what is important?
10. Integrative genome modeling platform reveals essentiality of rare contact events in 3D genome organizations
11. Xist spatially amplifies SHARP/SPEN recruitment to balance chromosome-wide silencing and specificity to the X chromosome
12. Single-cell measurement of higher-order 3D genome organization with scSPRITE
13. SPRITE: a genome-wide method for mapping higher-order 3D interactions in the nucleus using combinatorial split-and-pool barcoding
14. Nuclear compartmentalization as a mechanism of quantitative control of gene expression
15. The 4D nucleome project
16. Integrated spatial genomics reveals global architecture of single nuclei
17. Robust transcriptome-wide discovery of RNA-binding protein binding sites with enhanced CLIP (eCLIP)
18. The NIH BD2K center for big data in translational genomics
19. The Xist lncRNA interacts directly with SHARP to silence transcription through HDAC3.
20. Mutations causing medullary cystic kidney disease type 1 lie in a large VNTR in MUC1 missed by massively parallel sequencing
21. The bipartite TAD organization of the X-inactivation center ensures opposing developmental regulation of Tsix and Xist
22. Phase separation drives X-chromosome inactivation: a hypothesis
23. P705: ChIP-DIP: A highly multiplexed method for mapping DNA-associated proteins to study the epigenomic landscape
24. A high-resolution map of human evolutionary constraint using 29 mammals.
25. Identifying novel constrained elements by exploiting biased substitution patterns
26. SPIDR: a highly multiplexed method for mapping RNA-protein interactions uncovers a potential mechanism for selective translational suppression upon cellular stress
27. The genomic and cellular basis of biosynthetic innovation in rove beetles
28. Xist recruits the X chromosome to the nuclear lamina to enable chromosome-wide silencing
29. The NORAD lncRNA assembles a topoisomerase complex critical for genome stability
30. 3D genome organization around nuclear speckles drives mRNA splicing efficiency
31. RAP-MS: A Method to Identify Proteins that Interact Directly with a Specific RNA Molecule in Cells
32. Simultaneous mapping of 3D structure and nascent RNAs argues against nuclear compartments that preclude transcription
33. Publisher Correction: A protein assembly mediates Xist localization and gene silencing
34. RNA and dynamic nuclear organization
35. Corrigendum: The 4D nucleome project
36. The Xist IncRNA Exploits Three-Dimensional Genome Architecture to Spread Across the X Chromosome
37. How non-coding RNAs shape nuclear structure to regulate gene expression
38. Publisher Correction: The NORAD lncRNA assembles a topoisomerase complex critical for genome stability
39. Unbiased Reconstruction of a Mammalian Transcriptional Network Mediating Pathogen Responses
40. Many Human Large Intergenic Noncoding RNAs Associate with Chromatin-Modifying Complexes and Affect Gene Expression
41. Xist spatially amplifies SHARP recruitment to balance chromosome-wide silencing and specificity to the X chromosome
42. RNA Antisense Purification (RAP) for Mapping RNA Interactions with Chromatin
43. Integrative Genome Modeling Platform reveals essentiality of rare contact events in 3D genome organizations
44. Single-cell measurement of higher-order 3D genome organization with scSPRITE
45. Essential Roles for RNA in Shaping Nuclear Organization
46. Modular regulatory principles of large non--coding RNAs
47. lincRNAs act in the circuitry controlling pluripotency and differentiation
48. RNA FUNCTION: RNA and dynamic nuclear organization
49. Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals
50. Local regulation of gene expression by lncRNA promoters, transcription and splicing
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