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47 results on '"Gutierrez-Fernández, José"'

3. Risk factors associated with colistin resistance in carbapenemase-producing Enterobacterales: a multicenter study from a low-income country

Author

Soria-Segarra Claudia, Soria-Segarra Carmen, Diaz Andrés, Miranda-Ayala Marcela, Cevallos-Apolo Kerly, Bombón Moreno Bryan, Chuzan J. John, and Gutierrez-Fernández José

Subjects
Colistin, Resistance, Carbapenemase-producing, Enterobacterales, Risk factors, Therapeutics. Pharmacology, RM1-950, Infectious and parasitic diseases, RC109-216, Microbiology, QR1-502
Abstract

Abstract Purpose The aim of this study was to assess the risk factors for colistin-resistant carbapenemase-producing Enterobacterales (CR-CPE), and describe the mortality associated with this organism, in a low-income country. Methods A descriptive, observational, and prospective multicenter study was carried out in Guayaquil, Ecuador. All patients with carbapenem-resistant Enterobacterales admitted between December 2021 and May 2022 were enrolled. Infection definitions were established according to the Centers for Disease Control and Prevention (CDC) protocols. The presence of carbapenemase-producing Enterobacterales was confirmed with a multiplex PCR for bla KPC, bla NDM, bla OXA-48, bla VIM, and bla IMP genes. MCR-1 production was studied molecularly, and MLST assays were carried out. Results Out of 114 patients enrolled in the study, 32 (28.07%) had at least one positive sample for CR-CPE. Klebsiella pneumoniae ST512-KPC-3 was the most frequent microorganism isolated. Parenteral feeding, β-lactamase inhibitor use, recent hemodialysis, and renal failure were all considered independent risk factors for carrying CR-CPE. A mortality of 41.22% was detected, but we could not find any difference between colistin-resistant and colistin-susceptible CPE. MCR-1 production was not detected in any of the isolates studied. Conclusion A significant burden for CR-CPE was found in a South American country that was mainly caused by the high-risk clone K. pneumoniae ST512-KPC-3 and not mediated by mcr-1 production. Its acquisition involved parenteral feeding, β-lactamase inhibitor use, recent hemodialysis, and renal failure as independent risk factors, demonstrating the critical need for infection prevention and stewardship programs to avoid dissemination to other countries in the region.

Published
2023
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22. Presencia emergente de Pasteurella bettyae en el aparato genital de una mujer

Author

Gómez-Camarasa, Cristina, Foronda-García-Hidalgo, Carla, Borrego Jiménez, Jaime, Fernández-Parra, Jorge, and Gutierrez-Fernández, José

Subjects
infección genital, Pasteurella bettyae, infección emergente, genital infection, emerging infection
Abstract

A clinical case is described where the presence of Pasteurella bettyae in an endocervical exudate in a 45-year-old patient is demonstrated, but it cannot be assured as the sole cause of the infection. Its presence may indicate a colonization, although this microorganism is not recognized as part of the human microbiota. Despite its rarity, thanks to the Maldi-Tof test applied to colonies that grow in culture media, it is possible to know the infrequent presence of this type of microorganism., Se describe un caso clínico donde se demuestra la presencia de Pasteurella bettyae en un exudado endocervical en una paciente de 45 años, pero no se puede asegurar como la causa única de la infección. Su presencia puede indicar una colonización, aunque este microorganismo no es reconocido como parte de la microbiota humana. A pesar de su rareza, gracias a la prueba de Maldi-Tof aplicada a colonias que crecen en medios de cultivo, es posible conocer la presencia infrecuente de este tipo de microorganismo.

Published
2020

30. Preliminary evaluation of a new kit for differentiation of Mycobacterium tuberculosis complex species using Speed-Oligo MTBC

Author

Lara-Oya, Ana, primary, Rodríguez-Granger, Javier Moisés, additional, Liébana-Martos, María del Carmen, additional, Mendoza-López, Pablo, additional, Sampedro-Martínez, Antonio, additional, Cobo, Fernando, additional, Gutierrez-Fernández, José, additional, Martínez-Lirola, Miguel José, additional, and Navarro-Marí, José María, additional

Published
2016
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31. Molecular characterization and antimicrobial susceptibility of hemolytic Streptococcus agalactiae from post-menopausal women

Author

Moltó-García, Belén, primary, Liébana-Martos, María del Carmen, additional, Cuadros-Moronta, Elena, additional, Rodríguez-Granger, Javier, additional, Sampedro-Martínez, Antonio, additional, Rosa-Fraile, Manuel, additional, Gutierrez-Fernández, José, additional, Puertas-Priet, Alberto, additional, and Navarro-Marí, José María, additional

Published
2016
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39. Artritis tuberculosa sobre prótesis de rodilla: descripción de un caso y revisión de la literatura.

Author

Lara-Oya, Ana, Liébana-Martos, Maria del Carmen, Rodríguez-Granger, Javier, Sampedro-Martínez, Antonio, Aliaga-Martínez, Luis, Gutierrez-Fernández, José, and Navarro-Marí, José Maria

Abstract

Copyright of Revista Española de Quimioterapia is the property of Sociedad Espanola de Quimioterapia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2016

46. Diagnosis of leishmaniasis.

Author

Elmahallawy, Ehab Kotb, Sampedro Martínez, Antonio, Rodriguez-Granger, Javier, Hoyos-Mallecot, Yannick, Agil, Ahmad, Navarro Mari, José Marí, and Gutierrez Fernández, José

Subjects
*LEISHMANIASIS diagnosis, *PROTOZOAN diseases, *PARASITIC diseases, *LEISHMANIA, *IMMUNE response, *IMMUNOCOMPROMISED patients
Abstract

Leishmaniasis is a clinically heterogeneous syndrome caused by intracellular protozoan parasites of the genus Leishmania. The clinical spectrum of leishmaniasis encompasses subclinical ( not apparent), localized (skin lesion), and disseminated (cutaneous, mucocutaneous, and visceral) infection. This spectrum of manifestations depends on the immune status of the host, on the parasite, and on immunoinflammatory responses. Visceral leishmaniasis causes high morbidity and mortality in the developing world. Reliable laboratory methods become mandatory for accurate diagnosis, especially in immunocompromised patients such as those infected with HIV. In this article, we review the current state of the diagnostic tools for leishmaniasis, especially the serological test. [ABSTRACT FROM AUTHOR]

Published
2014
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