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15 results on '"Gutierrez, Ben"'

7. Tannin phenotyping of the Vitaceae reveals a phylogenetic linkage of epigallocatechin in berries and leaves

Author

Brillouet, Jean-Marc, primary, Romieu, Charles, additional, Bacilieri, Roberto, additional, Nick, Peter, additional, Trias-Blasi, Anna, additional, Maul, Erika, additional, Solymosi, Katalin, additional, Teszlák, Peter, additional, Jiang, Jiang-Fu, additional, Sun, Lei, additional, Ortolani, Danielle, additional, Londo, Jason P, additional, Gutierrez, Ben, additional, Prins, Bernard, additional, Reynders, Marc, additional, Van Caekenberghe, Frank, additional, Maghradze, David, additional, Marchal, Cecile, additional, Sultan, Amir, additional, Thomas, Jean-Francois, additional, Scherberich, Daniel, additional, Fulcrand, Helene, additional, Roumeas, Laurent, additional, Billerach, Guillaume, additional, Salimov, Vugar, additional, Musayev, Mirza, additional, Ejaz Ul Islam Dar, Muhammad, additional, Peltier, Jean-Benoit, additional, and Grisoni, Michel, additional

Published
2022
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8. Tannin phenotyping of the Vitaceae reveals a phylogenetic linkage of epigallocatechin in berries and leaves

Author

Brillouet, Jean-Marc, Romieu, Charles, Bacilieri, Roberto, Nick, Peter, Trias-Blasi, Anna, Maul, Erika, Solymosi, Katalin, Teszlák, Peter, Jiang, Jiang-Fu, Sun, Lei, Ortolani, Danielle, Londo, Jason P., Gutierrez, Ben, Prins, Bernard, Reynders, Marc, Van Caekenberghe, Frank, Maghradze, David, Marchal, Cécile, Sultan, Amir, Thomas, Jean-Francois, Scherberich, Daniel, Fulcrand, Hélène, Roumeas, Laurent, Billerach, Guillaume, Salimov, Vugar, Musayev, Mirza, Ejaz Ul Islam Dar, Muhammad, Peltier, Jean-Benoît, Grisoni, Michel, Brillouet, Jean-Marc, Romieu, Charles, Bacilieri, Roberto, Nick, Peter, Trias-Blasi, Anna, Maul, Erika, Solymosi, Katalin, Teszlák, Peter, Jiang, Jiang-Fu, Sun, Lei, Ortolani, Danielle, Londo, Jason P., Gutierrez, Ben, Prins, Bernard, Reynders, Marc, Van Caekenberghe, Frank, Maghradze, David, Marchal, Cécile, Sultan, Amir, Thomas, Jean-Francois, Scherberich, Daniel, Fulcrand, Hélène, Roumeas, Laurent, Billerach, Guillaume, Salimov, Vugar, Musayev, Mirza, Ejaz Ul Islam Dar, Muhammad, Peltier, Jean-Benoît, and Grisoni, Michel

Abstract

Background and Aims: Condensed tannins, responsible for berry and wine astringency, may have been selected during grapevine domestication. This work examines the phylogenetic distribution of condensed tannins throughout the Vitaceae phylogenetic tree. Methods: Green berries and mature leaves of representative true-to-type members of the Vitaceae were collected before 'véraison', freeze-dried and pulverized, and condensed tannins were measured following depolymerization by nucleophilic addition of 2-mercaptoethanol to the C4 of the flavan-3-ol units in an organic acidic medium. Reaction products were separated and quantified by ultrahigh pressure liquid chromatography/diode array detection/mass spectrometry. Key Results and Conclusions: The original ability to incorporate epigallocatechin (EGC) into grapevine condensed tannins was lost independently in both the American and Eurasian/Asian branches of the Vitaceae, with exceptional cases of reversion to the ancestral EGC phenotype. This is particularly true in the genus Vitis, where we now find two radically distinct groups differing with respect to EGC content. While Vitis species from Asia are void of EGC, 50 % of the New World Vitis harbour EGC. Interestingly, the presence of EGC is tightly coupled with the degree of leaf margin serration. Noticeably, the rare Asian EGC-forming species are phylogenetically close to Vitis vinifera, the only remnant representative of Vitis in Eurasia. Both the wild ancestral V. vinifera subsp. sylvestris as well as the domesticated V. vinifera subsp. sativa can accumulate EGC and activate galloylation biosynthesis that compete for photoassimilates and reductive power.

Published
2022

9. Belantamab mafodotin for the treatment of relapsed/refractory multiple myeloma in heavily pretreated patients: a US cost-effectiveness analysis

Author

Nikolaou, Andreas, primary, Ambavane, Apoorva, additional, Shah, Anshul, additional, Ma, Wenkang, additional, Tosh, Jon, additional, Kapetanakis, Venediktos, additional, Willson, Jenny, additional, Wang, Feng, additional, Hogea, Cosmina, additional, Gorsh, Boris, additional, Gutierrez, Ben, additional, Sapra, Sandhya, additional, Suvannasankha, Attaya, additional, and Samyshkin, Yevgeniy, additional

Published
2021
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11. Bridging the Gap Between RCTs and RWE Through Endpoint Selection

Author

LoCasale, Robert J., primary, Pashos, Chris L., additional, Gutierrez, Ben, additional, Dreyer, Nancy A., additional, Collins, Toby, additional, Calleja, Alan, additional, Seewald, Michael J., additional, Plumb, Jonathan M., additional, Liwing, Johan, additional, Tepie, Maurille Feudjo, additional, and Khosla, Sajan, additional

Published
2020
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12. Strengthening pharma's contract with society: the value of trusted partnerships between pharma and healthcare facilitated by real-world data

Author

Seewald, Michael J, primary, Plumb, Jonathan M, additional, Gutierrez, Ben, additional, Liwing, Johan, additional, Tepie, Maurille Feudjo, additional, Hammer, Mette, additional, LoCasale, Robert, additional, Khosla, Sajan, additional, Yin, Donald, additional, Pashos, Chris L, additional, and Nagy, Mark, additional

Published
2020
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13. Strengthening pharma's contract with society: the value of trusted partnerships between pharma and healthcare facilitated by real-world data

Author

Seewald, Michael J, Plumb, Jonathan M, Gutierrez, Ben, Liwing, Johan, Tepie, Maurille Feudjo, Hammer, Mette, LoCasale, Robert, Khosla, Sajan, Yin, Donald, Pashos, Chris L, and Nagy, Mark

Abstract

This White Paper is authored by 11 industry real-world evidence (RWE) experts, with support from IQVIA, as part of the ‘RWE Leadership Forum’: a group of Industry Leaders who come together as noncompetitive partners to understand and respond to internal or external RWD/E challenges and opportunities with a single expert voice. Herein we aim to clarify the rules of engagement between pharma and healthcare in order to establish trust-based partnerships, which will unlock unique value for society, including the medical community and the ultimate beneficiary, the patient.

Published
2024
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14. Profitability in Heterogeneity : a Comparative Study

Author

Gutierrez, Ben and Gutierrez, Ben

Subjects
Teams in the workplace Clergy., Leadership Clergy., Leadership Religious aspects Christianity., Équipes de travail Clergé., Leadership Clergé., Leadership Aspect religieux Christianisme., Leadership Religious aspects Christianity.
Abstract

This study relates Hambrick and Mason's (1984) Proposition 21 of the Upper Echelons Theory (UET) to the texts of I and II Timothy. Proposition 21 of the UET states, "In turbulent environments, team heterogeneity will be positively associated with profitability" (p. 203). This study affirms the validity of this proposition within the heterogeneous leadership context of Paul and Timothy as seen in the turbulent environment described in I and II Timothy. After defining three key terms (heterogeneity, turbulent environment, profitability) of the UET, this study provides the definitions and rationale for translating these terms into a ministry context. This study supports a heterogeneous leadership relationship of Paul and Timothy by providing a brief sketch of Paul and Timothy's personal background (birthplace, family, education, conversion experience, age) and past leadership experiences. This study supports that Paul and Timothy were functioning within a turbulent environment by providing a basic explanation of the nature of the heresies within I and II Timothy including a brief discussion of the identity of the heretics. The injunctions set forth for the Ephesian church and its conduct afterwards provide supporting evidence of the profitability aspect of Proposition 21. A summary of the study, benefits from this study, and suggestions for future research conclude this study.

Published
2004

15. The dynamics of brand choice behaviour in selected personal care products in urban Philippines

Author

Gutierrez, Ben Paul Baltazar

Subjects
1505 Marketing, Faculty of Business and Law, brand choice, shampoo, toothpaste, purchasing decisions, consumption, consumers, consumer behaviour, consumer decision making, brands, mathematical models, usage patterns, attiudinal profiles, consideration sets, Philippines, Manila
Abstract

This thesis investigates the dynamics of brand choice behaviour in shampoo and toothpaste products in urban Philippines. A review of theories highlights that American researchers dominate in brand choice literature and very few studies consider the context of less developed countries.

Published
1998

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