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7. Microbial Production of Bioactive Compounds

Author

Cabanillas-Bojórquez, Luis A., Valdez-Baro, Octavio, Gutiérrez-Grijalva, Erick Paul, Heredia, J. Basilio, Patra, Jayanta Kumar, Series Editor, Das, Gitishree, Series Editor, Sarkar, Angana, editor, and Ahmed, Idris Adewale, editor

Published
2023
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9. Contributors

Author

Ambriz-Pérez, Dulce Libna, primary, Antunes-Ricardo, Marilena, additional, Aviles-Gaxiola, Sara, additional, Benavides, Jorge, additional, Bergés-Tiznado, Magdalena Elizabeth, additional, Cabanillas-Bojórquez, Luis Angel, additional, Cerda-Sumbarda, Yadira Denisse, additional, Contreras-Angulo, Laura Aracely, additional, Criollo-Mendoza, Marilyn S., additional, Elizalde-Romero, Cristina A., additional, García-Aguiar, Israel, additional, García-Carrasco, Melissa, additional, Gayathri, M., additional, Ghosh, Souvik, additional, Gómez-Favela, Mario Armando, additional, Guajardo-Flores, Daniel, additional, Gutiérrez-Grijalva, Erick P., additional, Heredia, J. Basilio, additional, Jacobo-Velázquez, Daniel A., additional, Jiménez-Ortega, Luis Alfonso, additional, Licea-Claverie, Angel, additional, Martínez-Ávila, Mariana, additional, Montoya-Inzunza, Luis Aurelio, additional, Moreira-Rodríguez, Melissa, additional, Osuna-Martínez, Ulises, additional, Picos-Corrales, Lorenzo A., additional, Picos-Salas, Manuel A., additional, Ruelas-Leyva, Jose P., additional, Santos-Ballardo, David Ulises, additional, Sarmiento-Sánchez, Juan I., additional, Teredesai, Shreya Vinit, additional, and Zizumbo-Lopez, Arturo, additional

Published
2023
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13. Diseases with the highest mortality

Author

Aviles-Gaxiola, Sara, primary, Criollo-Mendoza, Marilyn S., additional, García-Carrasco, Melissa, additional, Gutiérrez-Grijalva, Erick P., additional, García-Aguiar, Israel, additional, and Heredia, J. Basilio, additional

Published
2023
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16. Treatment With Kiwi Peel Extract Delays Browning in Ready‐to‐Eat Lettuce.

Author

Fraudentali, Ilaria, Pedalino, Chiara, Furlani, Adriana, Secchiero, Andrea, Rogers, Hilary J., Gallo, Valentina, Antonini, Giovanni, Angelini, Riccardo, Cona, Alessandra, and Gutiérrez-Grijalva, Erick

Abstract

Browning reactions caused by oxidative stress occurring during postharvest procedures significantly compromise the quality of ready‐to‐eat (RTE) vegetables, negatively affecting their market value. Polyphenol oxidase (PPO) and peroxidase (POD) are two major enzymes involved in this phenomenon, as they oxidize phenolic compounds to quinones, which in turn polymerize to brown pigments. Recently, there has been an increasing interest in developing antibrowning treatments using food by‐products. Herein, the efficiency of a kiwi peel extract in reducing enzymatic browning of minimally processed lettuce (Lactuca sativa) has been investigated. PPO and POD activities showed an opposite spatial distribution within the leaf, with a higher POD activity in the midvein (MV) and in the inner lamina tissues, and a prevalence of PPO activity in the mesophyll. Considering that MV lignified tissues are those mainly affected by browning, the temporal trend of POD activity over a 20‐day storage period at 4°C was investigated. Data showed that treatment with a kiwi peel extract hinders both the increasing trend of POD activity and browning development compared to control leaves. These results could be potentially useful for the industry as they confirm that natural extracts, such as kiwi peel extract, can be valuable for extending the shelf‐life of RTE products. [ABSTRACT FROM AUTHOR]

Published
2024
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17. The Underlying Molecular Mechanisms of the Placenta Accreta Spectrum: A Narrative Review.

Author

Lizárraga-Verdugo, Erik, Beltrán-Ontiveros, Saúl Armando, Gutiérrez-Grijalva, Erick Paul, Montoya-Moreno, Marisol, Gutiérrez-Arzapalo, Perla Y., Avendaño-Félix, Mariana, Gutiérrez-Castro, Karla Paola, Cuén-Lazcano, Daniel E., González-Quintero, Paul, and Mora-Palazuelos, Carlos Ernesto

Subjects
SCIENTIFIC literature, PLACENTA accreta, GENE expression, NOTCH signaling pathway, NON-coding RNA, CESAREAN section
Abstract

Placenta accreta spectrum (PAS) disorders are characterized by abnormal trophoblastic invasion into the myometrium, leading to significant maternal health risks. PAS includes placenta accreta (invasion < 50% of the myometrium), increta (invasion > 50%), and percreta (invasion through the entire myometrium). The condition is most associated with previous cesarean deliveries and increases in chance with the number of prior cesarians. The increasing global cesarean rates heighten the importance of early PAS diagnosis and management. This review explores genetic expression and key regulatory processes, such as apoptosis, cell proliferation, invasion, and inflammation, focusing on signaling pathways, genetic expression, biomarkers, and non-coding RNAs involved in trophoblastic invasion. It compiles the recent scientific literature (2014–2024) from the Scopus, PubMed, Google Scholar, and Web of Science databases. Identifying new biomarkers like AFP, sFlt-1, β-hCG, PlGF, and PAPP-A aids in early detection and management. Understanding genetic expression and non-coding RNAs is crucial for unraveling PAS complexities. In addition, aberrant signaling pathways like Notch, PI3K/Akt, STAT3, and TGF-β offer potential therapeutic targets to modulate trophoblastic invasion. This review underscores the need for interdisciplinary care, early diagnosis, and ongoing research into PAS biomarkers and molecular mechanisms to improve prognosis and quality of life for affected women. [ABSTRACT FROM AUTHOR]

Published
2024
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18. Current Evidence of Natural Products against Overweight and Obesity: Molecular Targets and Mechanisms of Action.

Author

Elizalde-Romero, Cristina Alicia, Leyva-López, Nayely, Contreras-Angulo, Laura Aracely, Cabanillas Ponce de-León, Rigoberto, Rodriguez-Anaya, Libia Zulema, León-Félix, Josefina, Heredia, J. Basilio, Beltrán-Ontiveros, Saul Armando, and Gutiérrez-Grijalva, Erick Paul

Subjects
DIETARY patterns, METABOLIC syndrome, CARDIOVASCULAR diseases, NATURAL products, DRUG target
Abstract

Overweight and obesity are global health and economic concerns. This disease can affect every system of the human body and can lead to complications such as metabolic syndrome, diabetes, cancer, dyslipidemia, cardiovascular diseases, and hypertension, among others. Treatment may sometimes include diet, exercise, drugs, and bariatric surgery. Nonetheless, not all people have access to these treatments, and public health strategies consider prevention the most important factor. In this regard, recent investigations are aiming to find alternatives and adjuvants for the treatment of obesity, its prevention, and the reversion of some of its complications, using natural sources of anti-obesogenic compounds like polyphenols, terpenes, alkaloids, and saponins, among others. In this review, we gather the most current information using PubMed, Google Scholar, Scopus, Cochrane, and the Web of Science. We present and discuss the current information about natural products that have shown anti-obesogenic effects at a molecular level. We also consider the impact of dietary habits and lifestyle on preventing overweight and obesity due to the evidence of the benefits of certain foods and compounds consumed regularly. We discuss mechanisms, pathways, and receptors involved in the modulation of obesity, especially those related to inflammation and oxidative stress linked to this disease, due to the relevance of these two aspects in developing complications. [ABSTRACT FROM AUTHOR]

Published
2024
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27. Nano-formulations in drug delivery

Author

Garcia-Carrasco, Melissa, primary, Parra-Aguilar, Itzel F., additional, Gutiérrez-Grijalva, Erick P., additional, Licea-Claverie, Angel, additional, and Basilio Heredia, J., additional

Published
2022
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28. Contributors

Author

Agarwal, Tarun, primary, Amirrah, Ibrahim N., additional, Anandharamakrishnan, C., additional, Ansari, Aafreen, additional, Arooj, Mahreen, additional, Bandara, Nandika, additional, Banjara, Nabaraj, additional, Barui, Ananya, additional, Basilio Heredia, J., additional, Bhunia, Kanishka, additional, Bose, Samprit, additional, Chawdhary, Rashmi, additional, Chetri, Rahul, additional, Dasgupta, Nandita, additional, Dasgupta, Shalini, additional, Datta, Pallab, additional, Dharmalingam, Sangeetha, additional, Dwari, Dipanjan, additional, Erkinbaev, Chyngyz, additional, Fauzi, Mh Busra, additional, Garcia-Carrasco, Melissa, additional, Ghosal, Anujit, additional, Gorhe, Nikhil, additional, Gutiérrez-Grijalva, Erick P., additional, Hada, Vaishnavi, additional, Hadem, Hushnaara, additional, Hameed, Mehavesh, additional, Hashmi, S.A.R., additional, Hettiarachchy, Navam, additional, Holliday, Darryl L., additional, Hulle, Nishant Rachayya Swami, additional, Jagajjanani Rao, K., additional, Jaiswal, Lily, additional, Jian, Law Xia, additional, Kamaruzaman, Nurkhuzaiah, additional, Khan, Manal, additional, Korumilli, Tarangini, additional, Kugarajah, Vaidhegi, additional, Law, Jia Xian, additional, Licea-Claverie, Angel, additional, Limayem, Alya, additional, Lokanathan, Yogeswaran, additional, Mahalakshmi, L., additional, Maiti, Tapas Kumar, additional, Maity, Sourav, additional, Mazlan, Zawani, additional, Mili, Medha, additional, Mishra, Bhartendu Nath, additional, Mohamed, Ahmed A., additional, Moses, J.A., additional, Mukherjee, Soma, additional, Naik, Ajay, additional, Nath, Debarshi, additional, Ng, Min Hwei, additional, Nie, Lei, additional, Nongmaithem, Sophia Devi, additional, Nor, Fatimah Mohd, additional, Ojha, Atul Kumar, additional, Pal, Abhinandan, additional, Pal, Kunal, additional, Panicker, Seema, additional, Parra-Aguilar, Itzel F., additional, Prashant, N., additional, Rad, Niloofar Khoshdel, additional, Ram, Mukesh Kumar, additional, Ramachandran, Rani Puthukulangara, additional, Ranjan, Shivendu, additional, Roy, Akash, additional, Sagiri, Sai Sateesh, additional, Saha, Sayandeep, additional, Salleh, Atiqah, additional, Sallehuddin, Nusaibah, additional, Santhosh, R., additional, Sarkar, Angana, additional, Sarkar, Preetam, additional, Shankar, Shiv, additional, Shehadi, Ihsan, additional, Smandri, Ali, additional, Srivastava, A.K., additional, Sulaiman, Nadiah, additional, Tan, Sheri-Ann, additional, Vellaichamy, Chelladurai, additional, Verma, Sarika, additional, Vosough, Massoud, additional, Yoha, K.S., additional, Zahmatkesh, Ensieh, additional, Zarkesh, Ibrahim, additional, and Zulkiflee, Izzat, additional

Published
2022
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29. Contributors

Author

Abdulhameed, Sabu, primary, Abdul Manas, Nor Hasmaliana, additional, Adriana, Clementz, additional, Aguilar, Cristóbal N., additional, Aguilar-García, Ricardo D., additional, Aguilar-Zárate, Pedro, additional, Aguilera-Carbó, A.F., additional, Akanbi, Taiwo O., additional, Alva-Sánchez, Diana Laura, additional, Alvarez-Ossorio, Carmen, additional, de Andrade Soares, Eduarda Nataly, additional, Annapure, Uday S., additional, Arredondo-Valdes, Roberto, additional, Arun, K.B., additional, Arya, Shailendra Kumar, additional, Ascacio-Valdés, J.A., additional, Ávila-Alvarez, Kassandra T., additional, Baeza-Jiménez, Ramiro, additional, Bagagli, Marcela Pavan, additional, Balagurusamy, Nagamani, additional, Bald, Carlos, additional, Barros, Margarida Maria, additional, Barrow, Colin J., additional, Basheer, Soorej M., additional, Bezus, Brenda, additional, Binod, Parameswaran, additional, Bolivar, German, additional, Borderías, A. Javier, additional, Bucher, Tamara, additional, Buenrostro-Figueroa, Juan, additional, Cabanillas-Bojórquez, Luis A., additional, Carvalho, Filipe, additional, Carvalho, Pedro Luiz Pucci Figueiredo de, additional, Cavalitto, Sebastián, additional, Cavello, Ivana, additional, Cekmecelioglu, Deniz, additional, Chandel, Heena, additional, Chávez-González, Mónica L., additional, Chellappan, Sreeja, additional, Chozhavendhan, S., additional, Contreras-Esquivel, Juan Carlos, additional, Corona-Flores, J.D., additional, Cuellar-Rincón, Iris R., additional, Diana, Romanini, additional, dos Santos, P.N., additional, Efigenia, Montalvo González, additional, Elgui de Oliveira, Deilson, additional, Emmanual, Shibitha, additional, Erik Gustavo, Tovar-Pérez, additional, Alessa Esperón-Rojas, Alaina, additional, Fernandes, Pedro, additional, Fernández-Sanromán, Ángel, additional, Fleuri, Luciana Francisco, additional, García Figueroa, Alexis, additional, Gaur, Shivani Singh, additional, Genezini dos Santos, Andressa, additional, Gonçalves, Daniela A., additional, Govea-Salas, Mayela, additional, Gunathilake, Tharuka, additional, Shyamlal Gupta, Sugriv, additional, Gutiérrez-Grijalva, Erick Paul, additional, Heredia, J. Basilio, additional, Hernández-Almanza, Ayerim Yedid, additional, Hernández-Beltran, Javier Ulises, additional, Hernández-De Lira, Inty Omar, additional, Hong, Pui Khoon, additional, Huang, Chieh Chen, additional, Ibarruri, Jone, additional, Ilyina, Anna, additional, Iñarra, Bruno, additional, Jauregi, Paula, additional, Juárez-Enríquez, Edmundo, additional, Kamble, Asmita Deepak, additional, Kaur, Anupreet, additional, Kaushal, Jyoti, additional, Koike, Meliane Akemi, additional, Laureana, Guerra, additional, Levario-Gómez, Anahí, additional, María de Lourdes, García-Magaña, additional, Madhavan, Aravind, additional, Mano, M.C.R., additional, Martha Guillermina, Romero-Garay, additional, Martínez-Hernández, José L., additional, Mathew, Gincy Marina, additional, Mejía-López, A., additional, Moctezuma-Dávila, Karime de M., additional, Molina, G., additional, Moreno, Helena M., additional, Moreno-Sánchez, O., additional, Méndez-Carmona, J.Y., additional, Gabriela Mendoza-Sánchez, Liliana, additional, Muñiz-Márquez, Diana B., additional, Nair, Preetha, additional, Nava-Reyna, Erika, additional, Nobre, Clarisse, additional, Novelli, Paula Kern, additional, Nunes, Hysla Maria Albuquerque Resende, additional, Ochoa-Reyes, Emilio, additional, Pandey, Ashok, additional, Paulino, B.N., additional, Pedrosa, Mercedes M., additional, Rajamehala, M., additional, Ramli, Aizi Nor Mazila, additional, Ramos-González, Rodolfo, additional, Rebolloso-Padilla, O.N., additional, Polania Rivera, Anna María, additional, Rodríguez-Gutiérrez, L., additional, Ruelas-Chacon, X., additional, Ruzene, Denise Santos, additional, Sabu, A., additional, Sanjuvikasini, V., additional, San Martin, David, additional, Sanromán, M. Ángeles, additional, Santos, Brenda Lohanny Passos, additional, Sathyanarayana, Sowmya R., additional, Scarlett, Christopher J., additional, Segura-Ceniceros, Elda P., additional, Sergio García, Hugo, additional, Sharma, Archita, additional, Shruthi, S., additional, Silva, Daniel Pereira, additional, Sindhu, Raveendran, additional, Singh, Gursharan, additional, Singh, Harinder, additional, Sosa-Herrera, Aldo, additional, Sánchez-Muñoz, María Alejandra, additional, Taddia, Antonela, additional, Talavera-Caro, Alicia Guadalupe, additional, Tania Patricia, Castro-Jácome, additional, Teixeira, José A., additional, Tirado-Gallegos, Juan M., additional, Toro, Cristina Ramírez, additional, Tovar, Clara A., additional, Tubio, Gisela, additional, Uranga-Soto, Manuel A., additional, Uzuner, Sibel, additional, Van Vuong, Quan, additional, Verma, Madan L., additional, Vijay Pradhap Singh, M., additional, Wan Azelee, Nur Izyan, additional, Wang, Bo, additional, Wong-Paz, Jorge E., additional, Zanutto-Elgui, Mirella Rossitto, additional, and Zufia, Jaime, additional

Published
2022
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37. Optimized Ultrasonic Extraction of Essential Oil from the Biomass of Lippia graveolens Kunth Using Deep Eutectic Solvents and Their Effect on Colletotrichum asianum.

Author

Manjarrez-Quintero, Juan Pablo, Valdez-Baro, Octavio, García-Estrada, Raymundo Saúl, Contreras-Angulo, Laura Aracely, Bastidas-Bastidas, Pedro de Jesús, Heredia, J. Basilio, Cabanillas-Bojórquez, Luis Angel, and Gutiérrez-Grijalva, Erick Paul

Subjects
PEST control, ESSENTIAL oils, LIPPIA (Genus), ORGANIC solvents, BIOMASS
Abstract

Essential oils are emerging as alternatives to conventional pest control chemicals. Lippia graveolens Kunth (Mexican oregano) is a source of essential oils and during conventional extraction, the biomass generated is discarded as waste; however, reports show that this biomass is still a rich source of essential oils. Conventional essential oil extraction causes contamination and utilizes toxic solvents. Deep eutectic solvents (DESs) offer low toxicity, biodegradability, high selectivity, and yields comparable to organic solvents. This study obtained essential oil from Lippia graveolens biomass via hydrodistillation with ultrasound-assisted DES pretreatment. This research aimed to optimize the extraction of essential oil from Lippia graveolens biomass using ultrasound-assisted DESs and assess its in vitro and in vivo inhibitory effect on C. asianum. The response variables were extraction yield and total reducing capacity. Optimal conditions were determined using a central composite rotatable design, considering solid-to-liquid ratio (0.38 g/mL), ultrasonic amplitude (45.05%), and time (7.47 min). The optimized oil, with thymol (48%) as the predominant component, exhibited more volatile compounds than conventional hydrodistillation. Fungicidal assays highlighted its potential in controlling anthracnose in papaya fruits caused by C. asianum, making ultrasound-assisted DES pretreatment a promising alternative for obtaining essential oil from botanical byproducts. [ABSTRACT FROM AUTHOR]

Published
2024
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41. Snack of corn and roselle calyx residues: process optimization.

Author

Manuel Rivera-Castro, Víctor, Gutiérrez-Dorado, Roberto, Paul Gutiérrez-Grijalva, Erick, Basilio Heredia, José, and Dolores Muy-Rangel, María

Subjects
CALYX, ROSELLE, PROCESS optimization, RESPONSE surfaces (Statistics), CORN, ALMOND
Abstract

Rich in fiber and bioactive compounds, roselle calyx decoction residues offer opportunities in food processing. This study sought to develop a directly expanded snack with a mixture of corn and roselle calyx decoction residues, optimizing its physical qualities. It was conducted in 2023, using the response surface methodology with three factors and three responses. The directly expanded snack showed expansion index values between 1.75 to 2.64, bulk density of 0.15 to 0.38 g cm-3 and firmness of 6.8 to 19.6 N, with attractive purple-lilac shades. The regression models were adequate and using the desirability method, optimal conditions (OT= 132.3 °C, SS= 240 rpm) and roselle inclusion level (J= 12.4%) were determined for an optimized directly expanded snack. It was concluded that the inclusion of up to 12.4% of roselle calyx allowed obtaining snacks with excellent physical characteristics. [ABSTRACT FROM AUTHOR]

Published
2024
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46. Caracterización y hallazgos asociados de vertebras transicionales de la columna lumbosacra por resonancia magnética de columna lumbar

Author

Jiménez-De La O, Edgar Ricardo, primary, Morales-Sánchez, Francisco Fernando, additional, Zatarain-Bayliss, Lucía, additional, Rochín-Terán, Juan Luis, additional, Zavala-Castillo, Juan Miguel, additional, Gutiérrez-Grijalva, Erick Paul, additional, Avendaño-Félix, Mariana, additional, Moreno-Ortiz, José Miguel, additional, and Verdugo-Rosas, Abraham, additional

Published
2023
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48. Naringenin as a Natural Agent Against Oxidative Stress and Inflammation, and Its Bioavailability.

Author

Picos-Salas, Manuel Adrian, Cabanillas-Bojórquez, Luis Ángel, Elizalde-Romero, Cristina Alicia, Leyva-López, Nayely, Montoya-Inzunza, Luis Aurelio, Heredia, J. Basilio, and Gutiérrez-Grijalva, Erick P.

Subjects
NARINGENIN, OXIDANT status, BIOAVAILABILITY, REACTIVE oxygen species, TRANSCRIPTION factors
Abstract

Naringenin is a flavanone commonly found in citrus and aromatic herbs that can protect against oxidative stress and inflammation. Oxidative stress can cause serious damage to tissues and organs; furthermore, it is closely related to chronic inflammation-related diseases, as reactive oxygen species can activate transcription factors that culminate in the production of pro-inflammatory molecules. The effects of naringenin against these responses are mediated by its antioxidant capacity and the induction or inhibition of signaling routes related to inflammation. Hence the current review summarizes the current knowledge of naringenin's health benefits against oxidative stress and inflammation, its mechanisms of action, and its bioavailability. [ABSTRACT FROM AUTHOR]

Published
2023
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50. Green Extracts and UPLC-TQS-MS/MS Profiling of Flavonoids from Mexican Oregano (Lippia graveolens) Using Natural Deep Eutectic Solvents/Ultrasound-Assisted and Supercritical Fluids

Author

Bernal-Millán, Manuel de Jesús, primary, Carrasco-Portugal, Miriam del Carmen, additional, Heredia, J. Basilio, additional, Bastidas-Bastidas, Pedro de Jesús, additional, Gutiérrez-Grijalva, Erick Paul, additional, León-Félix, Josefina, additional, and Angulo-Escalante, Miguel Ángel, additional

Published
2023
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