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19 results on '"Gutiérrez‐Aguirre, Homero"'

4. Improving acute promyelocytic leukemia (APL) outcome in developing countries through networking, results of the International Consortium on APL

Author

Rego, Eduardo M., Kim, Haesook T., Ruiz-Argüelles, Guillermo J., Undurraga, Maria Soledad, Uriarte, Maria del Rosario, Jacomo, Rafael H., Gutiérrez-Aguirre, Homero, Melo, Raul A.M., Bittencourt, Rosane, Pasquini, Ricardo, Pagnano, Katia, Fagundes, Evandro M., Chauffaille, Maria de Lourdes, Chiattone, Carlos S., Martinez, Lem, Meillón, Luis A., Gómez-Almaguer, David, Kwaan, Hau C., Garcés-Eisele, Javier, Gallagher, Robert, Niemeyer, Charlotte M., Schrier, Stanley L., Tallman, Martin, Grimwade, David, Ganser, Arnold, Berliner, Nancy, Ribeiro, Raul C., Lo-Coco, Francesco, Löwenberg, Bob, and Sanz, Miguel A.

Published
2013
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5. All-trans retinoic acid with daunorubicin or idarubicin for risk-adapted treatment of acute promyelocytic leukaemia: a matched-pair analysis of the PETHEMA LPA-2005 and IC-APL studies

Author

Sanz, Miguel A., Montesinos, Pau, Kim, Haesook T., Ruiz-Argüelles, Guillermo J., Undurraga, María S., Uriarte, María R., Martínez, Lem, Jacomo, Rafael H., Gutiérrez-Aguirre, Homero, Melo, Raul A. M., Bittencourt, Rosane, Pasquini, Ricardo, Pagnano, Katia, Fagundes, Evandro M., Vellenga, Edo, Holowiecka, Alexandra, González-Huerta, Ana J., Fernández, Pascual, De la Serna, Javier, Brunet, Salut, De Lisa, Elena, González-Campos, José, Ribera, José M., Krsnik, Isabel, Ganser, Arnold, Berliner, Nancy, Ribeiro, Raul C., Lo-Coco, Francesco, Löwenberg, Bob, Rego, Eduardo M., and on behalf of the IC-APL and PETHEMA and HOVON Groups

Published
2015
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7. Higher doses of CD34+ progenitors are associated with improved overall survival without increasing GVHD in reduced intensity conditioning allogeneic transplant recipients with clinically advanced disease

Author

Gómez-Almaguer, David, Gómez-Peña, Álvaro, Jaime-Pérez, José Carlos, Gómez-Guijosa, Miguel Ángel, Cantú-Rodríguez, Olga, Gutiérrez-Aguirre, Homero, Martínez-Cabriales, Sylvia Aidé, García-Rodríguez, Fernando, Olguín-Ramírez, Leticia A., Salazar-Riojas, Rosario, and Méndez-Ramírez, Nereida

Published
2013
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10. Palliative Care for Patients With Hematologic Malignancies in a Low-Middle Income Country: Prevalence of Symptoms and the Need for Improving Quality of Attention at the End of Life

Author

Jaime-Pérez, José Carlos, primary, Turrubiates-Hernández, Grecia Abigayl, additional, Nava-Obregón, Teresa, additional, Coronado-Hernández, Blanca, additional, Gutiérrez-Aguirre, Homero, additional, Cantú-Rodríguez, Olga Graciela, additional, Herrera-Garza, José Luis, additional, and Gómez-Almaguer, David, additional

Published
2019
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11. Palliative Care for Patients With Hematologic Malignancies in a Low-Middle Income Country: Prevalence of Symptoms and the Need for Improving Quality of Attention at the End of Life.

Author

Jaime-Pérez, José Carlos, Turrubiates-Hernández, Grecia Abigayl, Nava-Obregón, Teresa, Coronado-Hernández, Blanca, Gutiérrez-Aguirre, Homero, Cantú-Rodríguez, Olga Graciela, Herrera-Garza, José Luis, and Gómez-Almaguer, David

Abstract

Background: Palliative care (PC) for patients with malignant hematological diseases is scarcely documented, particularly in low- and middle-income countries. This study aimed to document PC provided to patients with hematologic malignancies. Methods: Bidirectional study conducted from July 2016 to June 2019 at the hematology and palliative care departments at a reference center in Northeast Mexico for low-income open population uninsured patients. Clinical records and electronic files of patients with malignant hematological diseases of both sexes and all ages attending an academic hematology center were reviewed. Statistical analysis was performed with the SPSS version 22 program. Acute and chronic leukemias, multiple myeloma, Hodgkin lymphoma, non-Hodgkin lymphoma, and others were included. Results: Five-hundred ten patients were studied, of which 148 (29%) died. Eighty-one (15.88%) patients including 31 (20.9%) who died received PC. Median age at palliative diagnosis was 42 (2-91) years. The most common symptom was pain (69.7%). The most frequent reason for palliative referral was treatment-refractory disease (39%). During the last week of life, 19 (95%) of 20 patients had blood sampling; 17 (85%) received antibiotics; 16 (80%) had a urinalysis performed; 16 (80%) received analgesia, including paracetamol (11, 35.5%) and buprenorphine (7, 22.6%); 10 (50%) received blood products; 9 (45%) were intubated; and central venous catheters were inserted in 5 (25%) patients. Conclusions: Palliative care was provided to a minority of patients with hematologic malignancies and considerable improvement is required in its timely use and extension. [ABSTRACT FROM AUTHOR]

Published
2020
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12. Global representation among journal editors in haematology: are we diverse, equitable, and inclusive?

Author

Noyola-Pérez, Andrés, Gil-Flores, Lourdes, Martínez-Espinosa, Héctor A, Ramos-Barrera, Emilia, Rodríguez-González, Víctor, Sung, Lillian, Guzman, Mónica, Hamad, Nada, Colunga-Pedraza, Perla R, Tarín-Arzaga, Luz, Cantú-Rodríguez, Olga G, Gutiérrez-Aguirre, Homero, Jaime-Pérez, José Carlos, Gómez-Almaguer, David, and León, Andrés Gómez-De

Published
2023
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13. Cost Structure and Clinical Outcome of a Stem Cell Transplantation Program in a Developing Country: The Experience in Northeast Mexico

Author

Jaime-Pérez, José Carlos, primary, Heredia-Salazar, Alberto Carlos, additional, Cantú-Rodríguez, Olga G., additional, Gutiérrez-Aguirre, Homero, additional, Villarreal-Villarreal, César Daniel, additional, Mancías-Guerra, Consuelo, additional, Herrera-Garza, José Luís, additional, and Gómez-Almaguer, David, additional

Published
2015
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14. Chemotherapy Alone or HSCT After Reduced-Intensity Conditioning for Patients with Malignant Hematologic Diseases Are Not Associated to Metabolic Syndrome: A Cross-Sectional Observational Study

Author

Jaime-Pérez, José Carlos, primary, Reyes-Escobedo, Alfonso, additional, Martínez-De La Garza, Karina S., additional, Herrera-Garza, José Luis, additional, Cantú-Rodríguez, Olga G., additional, Gutiérrez-Aguirre, Homero, additional, and Gómez-Almaguer, David, additional

Published
2014
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16. Improving the Treatment Outcome of Acute Promyelocytic Leukemia in Developing Countries through International Cooperative Network. Report On the International Consortium On Acute Promyelocytic Leukemia Study Group.

Author

Rego, Eduardo M, primary, Kim, Haesook T., additional, Ruiz-Arguelles, Guillermo J., additional, Uriarte, Rosario, additional, Jacomo, Rafael H, additional, Gutiérrez-Aguirre, Homero, additional, Melo, Raul AM, additional, Bittencourt, Rosane, additional, Pasquini, Ricardo, additional, Pagnano, Katia BB, additional, Fagundes, Evandro M, additional, de Lourdes, Maria LF Chauffaille, additional, Chiattone, Carlos, additional, Martinez, Lem, additional, Meillon, Luis A, additional, Gomez-Almaguer, David, additional, Kwaan, Hau C., additional, Garces-Eisele, Javier, additional, Gallagher, Robert E, additional, Niemeyer, Charlotte M, additional, Lowenberg, Bob, additional, Ribeiro, Raul C, additional, Lo-Coco, Francesco, additional, and Sanz, Miguel A, additional

Published
2009
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19. The impact of medical education and networking on the outcome of leukemia treatment in developing countries. The experience of International Consortium on Acute Promyelocytic Leukemia (IC-APL).

Author

Rego, Eduardo M, Kim, Haesook T, Ruiz-Argüelles, Guillermo J, Uriarte, Maria del Rosario, Jacomo, Rafael H, Gutiérrez-Aguirre, Homero, Melo, Raul A M, Bittencourt, Rosane, Pasquini, Ricardo, Katia Pagnano, Fagundes, Evandro M, Chauffaille, Maria de Lourdes, Chiattone, Carlos, Martinez, Lem, Meillón, Luis A, Gómez-Almaguer, David, Kwaan1, Hau, Garcés-Eisele, Javier, Gallagher, Robert, and Niemeyer, Charlotte M

Subjects
LEUKEMIA treatment, ACUTE promyelocytic leukemia, CLINICAL trials, TRETINOIN, ANTHRACYCLINES, DAUNOMYCIN, DEVELOPING countries
Abstract

Objectives: Several clinical trials conducted in Europe and US reported favorable outcomes of patients with APL treated with the combination of all trans retinoic acid (ATRA) and anthracyclines. Nevertheless, the results observed in developing countries with the same regimen was poorer, mainly due to high early mortality mainly due bleeding. The International Consortium on Acute Promyelocytic Leukemia (IC-APL) is an initiative of the International Members Committee of the ASH and the project aims to reduce this gap through the establishment of international network, which was launched in Brazil, Mexico and Uruguay. Methods: The IC-APL treatment protocol is similar to the PETHEMA 2005, but changing idarubicin to daunorubicin. All patients with a suspected diagnosis of APL were immediately started on ATRA, while bone marrow samples were shipped to a national central lab where genetic verification of the diagnosis was performed. The immunofluorescence using an anti-PML antibody allowed a rapid confirmation of the diagnosis and, the importance of supportive measures was reinforced. Results: The interim analysis of 97 patients enrolled in the IC-APL protocol showed that complete remission (CR) rate was 83% and the 2-year overall survival and disease-free survival were 80% and 90%, respectively. Of note, the early mortality rate was reduced to 7.5%. Discussion: The results of IC-APL demonstrate the impact of educational programs and networking on the improvement of the leukemia treatment outcome in developing countries. [ABSTRACT FROM AUTHOR]

Published
2012
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