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WOS: 000075983300010 PubMed: 9770132 …

A case of lobar agenesis of the left upper lobe of the lung in a 3 year- old girl is presented. Althought this anomaly is usually associated with other congenital anomalies, our patient had no associated anomaly. Pulmonary perfusion scintiscan and chest computed tomography examinations were found to be useful diagnostic modalities in our case.

Fever, as being a first sign of many diseases, is an important problem in childhood for its results. In this study we aimed to determine the level of maternal knowledge about fever and their behavioral features when their children were in fever. We gave a questionnaire including 18 questions to 151 of the mothers of children who applied to the clinic of child health and diseases from 1 to 30 of June 1996 in our hospital. The average age of mothers was 29.85 ± 0.49, the educational state of 72 (47.7%) of mothers was primary school and 109 (72.3%) of them were housewives, Only 23 (15.2%) of mothers could define fever truly. Ninety-one (60.2%) of mothers had a thermometer at their home but 81 (53.6%) of them were using the thermometer only. Seventy-two (47.7%) of mothers were measuring the body temperature by putting the thermometer to armpit. Although a temperature of 38 degrees C was considered as fever by 53 (35.1%) of mothers, 18 (11.9%) of mothers considered a temperature of 37 degrees C as fever. One hundred (66.2%) of mothers were taking the child's clothes off and compressing with a wet cloth and 93 (61.6%) of them were consulting with a physician firstly. One hundred and thirty (86.0%) of mothers reported that they had an any kind of antipyretic agents at their home. Under the light of these findings, educating mothers about fever and training them to gain correct behavioral features should be useful for child health.

The effects of intralesional long-acting corticosteroid injection were investigated in rats with alkali-induced corrosive esophageal burns. In 30 rats, a standard esophageal burn was produced as described by Gehanno. The rats were then divided into three groups as follows: group I, rats with esophageal burns and parenteral antibiotic, group II, rats with esophageal burns and systemic corticosteroid and parenteral antibiotic, group III, rats with esophageal burns treated with antibiotic and intralesional long-acting corticosteroid. All animals were sacrified on the 21th day of experiment. Histopathologic evaluation was performed and collagen deposition in the submucosa, damage to the muscularis mucosa, damage and collagen deposition in the tunica muscularis were investigated for each group. Overall criteria for histopathologic evaluation in the group II were better than group I (p

Hydatic cyst can involve mostly in the liver and lung, and rarely in other organs. However, subcutaneous tissue involvement is very rare. Three-year-old girl admitted with the complaint of a swelling on the inferolateral margin of the left scapula. Radiological studies showed a hydatid cyst located on the thoracal wall; on the inferolateral margin of the left scapula along with bilateral lung cysts. Primarily, subcutaneous hydatid cyst is excised completely with it's fibrous capsule and then partial cystectomy and capitonage is performed for one cyst in the left lung through a left posterolateral thoracotomy. She is on follow up with a plan of intervention to the cysts of the right lung. This case of the subcutaneous hydatid cyst was discussed according to the literature.

We compared the effects of somatostation and ranitidine on treatment of stress ulcer on rats in an experimental study. Three groups were created; sham group, ranitidine group and somatostation group. Gastric mucosal damage index was measured in each group and Mann-Whitney U test was used for statistical analysis. Statistically, the mucosal damage index was significantly higher in thesomatostatin group comparing the control group (p>0.001) and also in the control group comparing the ranitidine group (p

Thirty newborn with gastrointestinal system perforations were managed at Pediatric Surgery Department of Ondokuz Mayis University, Faculty of Medicine from July 1980 to December 1994. Of these cases; 19 were mature, seven were premature and four were small for gestational age. Twenty-nine of them underwent emergent surgery, but one patient died because of his general deterioration before surgical intervention. We could not find the cause of perforation in 11 cases and the place of perforation in one case. The perforation sites in our cases were stomach (7), colon (7) ileum (8), cecum (4), duodenum (1) and both the stomach and the ileum in one case. These perforations most commonly occurred in association with the pathologies of the wall or the lumen of the gut such as intestinal atresia (1), anorectal malformation (3), necrotizing enterocolitis (3), meconium ileus (3), and congenital aganglionic megacolon (2) and less commonly result of compressing factors outside the bowel such as Ladd's bands (2), omphlomesenteric band (3) and vascular anomaly of the mesentery (1). A prompt and an appropriate surgical intervention was carried out for each patient according to the place of perforation. The overall mortality was 48% and the mortality in stomach perforations was found to be less than ileal, cecal and colonic perforations. The cause of death was 60% sepsis.

PubMed: 8971914 [No abstract available]

AYDIN, MURAT/0000-0001-7374-229X WOS: A1996UP29600003 PubMed: 8701477 To document the prevalence of asthma and other allergic disorders among children, a questionnaire study involving 3,118 children aged six to 14 years was done. The overall prevalence of allergic diseases was 27.4 percent and the prevalence of each disorder was as follows: rhinitis 11 percent, asthma 10.2 percent, conjunctivitis 7.1 percent, and skin diseases 6.3 percent. Atopic diseases were reported most commonly among the families of children with allergic rhinitis. When compared with Internal regions of Turkey, the prevalence of allergic diseases was found to be very high It was concluded that allergic diseases are an important health problem among children in our region.

Case records of 32 patients (22 female and 10 male) with sacrococygeal teratoma who were treated in our department between 1984 and 1994 were reviewed. 27 patients had benign sacrococygeal teratoma and the majority of the benign sacrococygeal teratomas were newborns. Total excision with coccygectomy was performed in this group. In contrast, only one of the patients with malignant tumor was a newborn. In malignant group excision and multiagent chemotherapy were used for the treatment and two recurrences were noted. The average survival was increased and early mortality was decreased for all patients in comparison with past decades.

Three rare anorectal malformation are presented: A two-month-old girl with a H-type congenital anovestibular fistula and normal anus. A case of a one-year-old boy with translevator type anal atresia and perineal fistula and bifid scrotum and a third case of five-month-old boy with an ectopic anus on the right gluteus. Anatomy, embryology and treatment of these rare anorectal malformation types are reviewed.

WOS: A1996VW50000037 PubMed: 8971914 …

WOS: A1996UW77200014 PubMed: 8818459 …

This experimental study aims to evaluate the relative effectiveness of splenic artery ligation and splenic autotransplantation as spleen-saving surgical procedures. Forty female Sprague-Dawley rats, weighing 162-270 g were divided into four groups: group I control, group II for splenectomy, group III for splenic artery ligation and group IV for splenic autotransplantation. Serum levels of complement 3 and 4 (C3, C4), immunoglobulin M, G, A (IgM, IgG, IgA) and fibronectin were measured, and control blood samples were cultured in all animals on the 30th postoperative day. On the 45th postoperative day Streptococcus pneumoniae type 25 was injected intraperitoneally, the same parameters tested 48th later. The animals were sacrificed after blood sampling to obtain lung tissue cultures. Penumococcal injections resulted in statistically significant differences in C3, IgM, fibronectin levels between the splenic artery ligation group (III) and the splenic autotransplantation group (IV). The sepsis induced by intraperitoneal Pneumococcus injection, colonization was detected in lung in group III and tissue cultures in 2 (20%) rats in group III and 4 (40%) rats in group IV. The elevated levels of C3, IgM and fibronectin in groups III and IV compared to group II were considered to be statistically significant (p < 0.01). These results indicated a statistically significant (p < 0.01) advantage of splenic artery ligation over autotransplantation.

Abdominoscrotal hydrocele (ASH) is a rarity among surgical pathologies. We herein report a bilateral case of ASH. We also point out that ASH should be considered in the differential diagnosis of lower abdominal masses.

Stress ulcers are acute gastric mucosal lesions developing as a result of the mucosal ischemia due to several initiating factors. It has been shown that the majority of tissue injury occurs during the reperfusion period when the oxygen derived free radicals, form and meet tissue. We have used an animal model to investigate the intensity and mechanism of tissue injury in stress ulceration with or without reperfusion. The role of oxygen radicals were also investigated. We have shown that the intensity of tissue injury is greatest in the reperfused group and that further injury can be prevented by deferoxamine which inhibits the formation of hydroxyl radicals.

An unusual case of heterotrophic brain tissue was confused with a malignant tumor of the face in a child. Such lesions are rare, but the diagnosis can be confirmed through frozen section examination. This has made the total excision of the mass possible in our case.

The effects of somatostatin and ranitidine on prophylaxis of stress ulcer are compared using three experimental groups of rats: Sham group, ranitidine group, and somatostatin group. Gastric mucosal damage index was measured in each group and Mann-Whitney U test was used for statistical analysis. Statistically, there was not any difference between the sham and the ranitidine groups (p > 0.05), but the mucosal damage index in the somatostatin group was significantly lower then in the sham and the ranitidine groups (p < 0.01). Somatostatin seems to be a more effective drug than ranitidine for the prophylaxis of stress ulcers.

WOS: A1995TA83000041 …

AYDIN, MURAT/0000-0001-7374-229X WOS: A1995UA43300010 PubMed: 7502363 Candidiasis is an opportunistic infection and may result in significant morbidity and mortality in neonates. Cerebral candidiasis is rare and usually associated with systemic candidiasis. Information concerning the toxicity and efficacy of antifungal therapy for neonates is limited. In this report, we present three neonates with candidiasis. All of the patients were premature with low birth weights, and received antibiotic therapy for one to four weeks before the onset of candidiasis. Candida albicans was isolated from cerebrospinal fluid cultures. Amphotericin B was given administered at an initial dose of 0.25 mg/kg/day intravenously (IV) and increased to a dosage of 2 mg/kg/day, and therapy was continued for three to four weeks. A transient and mild elevation in hepatic enzyme concentration was observed in two patients, and transient thrombocytopenia occurred in all of them.

Twenty eight cases with the diagnosis of goiter (one newborn (7/365 day) and the others aged between 9-16 years) were managed and treated at Ondokuz Mayis University, Faculty of Medicine, Pediatric Surgery Department, during June 1983 and April 1994. Of these cases 19 were female (67.8 %) and nine were male (32.2 %). We detected diffuse hyperplasia in eight patients, multinodular goiter in other eight patients and solitary nodular goiter in 12 patients. All cases were treated surgically. There were temporary postoperative complications in ten cases and the newborn patient died on the first postoperative day. Although in the literature it is strongly emphasized that there is an increased malignancy incidence in solitary thyroid nodule during childhood, we have not detected any histological malignancy in our series.

[No abstract available]

It has been shown that environmental temperature elevation as an in vitro equivalent of fever, a major symptom in childhood, increases the death of bacteria and decreases minimal inhibitory concentrations of antibiotics. The studies on this topic are not satisfactory and do not include human body temperatures and antibiotic deficient media as controls. In this study bactericidal effects of ceftriaxone on E. coli ATCC 25922 serogroup in temperatures 37 °C, 39 °C and 41 °C has been searched and compared with controls. The antibactericidal effectiveness has been found much more in 41 °C than in 37 °C and 39 °C (P < 0.05). We conclude that bactericidal effects of antibiotics are much more in high temperatures.

Usually it is possible to repair abdominal wall defects primarily. If the fascia defect is too large and not possible to repair it primarily synthetic materials can be used. In this study the results of our two cases (superior lumbar hernia and ventral hernia) which were repaired by using polytetrafluoroethylene synthetic materials were presented.

WOS: A1993MV43900008 PubMed: 8164343 The effects of smoking on maternal and cord plasma lipid and lipoprotein levels were measured in 40 smoker mothers and their newborns and compared to nonsmokers. Significantly higher levels of total cholesterol, low density lipoprotein cholesterol and very low density lipoprotein cholesterol and lower levels of high density lipoprotein cholesterol were found in smoker mothers and their newborns in comparison to nonsmokers. These results suggest that smoking does not affect only the lipids and lipoproteins of pregnant women but also those of their fetuses.

The effects of intraluminal short chain fatty acids (SCFAs) irrigation on colonic anastomosis, distal to the colostomy were investigated on 60 Swiss Albino male rats. Four groups each consists of randomly 15 rats were assigned. Out of group I (Sham group), loop colostomy 2.5 cm distal to the caecum were performed to all of the rats. While no additional procedures performed in group II, normal saline irrigation in group III and SCFAs irrigation in group IV, distal to the colostomy were performed. After 3 weeks, all the rats were reoperated, resection and anastomosis 5 cm distal to the caecum was performed. Irrigations were continued for one week and then the rats killed in order to investigate the anastomosis perforation pressure. In conclusion we demonstrated that irrigation with SCFAs increased the strength of colonic anastomosis.

A case of ileocolic intussusception due to cystic duplication of the caecum in a 8 months old girl is presented. A review of the literature reveals the extreme rarity of this entity.

We performed early decortication procedure to 22 cases during the period of February 1991 to December 1993 because of postpneumonic empyema. Fourteen of them were male and 8 of them were female. We evaluated these cases retrospectively. Decortication was saved for the patients that antimicrobial therapy and closed-tube drainage failed in treatment and performed on the 10-15th day after the diagnosis was established. Indications for the decortication were persistent fever (7), pulmonary air leakage (4), localised effusion (4), persistent respiratory distress (3) and pleural thickening without resolution (18). Decortication was performed through the standard posterolateral thoracotomy. Patients were discharged on the 6-9th postoperative day with minimal morbidity and none mortality. Because of the simplicity of the procedure; short hospitalisation period, low mortality and morbidity rates and good results were achieved with early decortication.

[No abstract available]

[No abstract available]

Background Cefoperazone has not been reported to cause vasculitic complications before. Here, we report a case of hypersensitivity vasculitis associated with cefoperazone/sulbactam. Case presentation A 13-year-old girl with appendicitis developed hypersensitivity vasculitis on the fifth day of cefoperazone/sulbactam therapy. Hypersensitivity vasculitis resolved gradually after removal of the agent on the seventh day and did not recur. Although hypersensitivity vasculitis has multiple causes, coexistence of hypersensitivity vasculitis and cefoperazone treatment, and the quite resolution of the disease after removal of the drug, strongly favours a causative relationship. Conclusion To our knowledge, this is the first report of a hypersensitivity vasculitis associated with cefoperazone.

PubMed: 3286135 The cases of seven patients between the ages of seven days and three years with purpura fulminans have been reviewed. Causative agents in these newborns were Escherichia coli, Enterobacter, and Staphylococcus; in older children they were varicella and E. coli. The clinical findings, medical and surgical interventions, and outcomes of the cases are presented here.

WOS: A1986G861900003 PubMed: 3296368 …

WOS: A1988N428200009 PubMed: 3286135 …

DIREN, HALDUN BARIS/0000-0001-8958-2040 WOS: A1987R856900003 PubMed: 3504072 …

A rare case of a nine years old boy diagnosed as juvenile dermatomyositis (JDM) is presented. On physical examination, he had malar rash, periorbital edema and erythema. There were symmetrical proximal muscle weakness, erythema on the extensor surfaces of the legs, over the hands and knees. In laboratory examination, LDH and CPK were found to be elevated. The pattern of inflammation in muscle was detected by electromyography. A skin and muscle biopsy was carried out from the lesions. Perivascular mononuclear inflammatory cell infiltration in the upper dermis and perivascular mononuclear cell infiltration with fiber necrosis in the muscle were seen. With these clinical and laboratory findings, JDM was diagnosed and a treatment regimen with prednisolone (2 mg/kg/day) was established. On the 15th day of treatment, the symptoms and the signs began to disappear. Prednisolone was tapered and switched to low maintenance dose. In duration of 7 months follow up, the patient was healthy and no recurrence was seen.