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Ras-related protein Rab-10 (RAB10) is involved in tumorigenesis and progression of hepatocellular carcinoma (HCC). Here, we found RAB10, O-GlcNAc transferase (OGT), and O-GlcNAcylation were upregulated in HCC. In addition, RAB10 protein level was prominently positively correlated with the expression of OGT. O-GlcNAcylation modification of RAB10 was then investigated. Here we showed that RAB10 interacts directly with OGT in HCC cell lines, Meanwhile, O-GlcNAcylation enhanced RAB10 protein stability. Furthermore, knockdown of OGT suppressed aggressive behaviors of HCC in vitro and in vivo, while elevated RAB10 reversed these. Taken together, these results indicated that OGT-mediated O-GlcNAcylation stabilized RAB10, thus accelerating HCC progression.

In this paper, a dual-parameter sensor based on surface plasmon resonance (SPR)-photonic crystal fiber (PCF) is proposed, which can be applied in detecting the magnetic field and temperature. In this sensor, two elliptical channels are designed on both sides of the fiber core. The left channel (Ch 1) is coated with gold film and filled with magnetic fluid (MF) to achieve a response to the magnetic field and temperature using SPR. The right channel (Ch 2) is coated with gold film as well as Ta

A surface plasmon resonance (SPR) sensor comprising photonic crystal fiber (PCF) is designed for magnetic field and temperature dual-parameter sensing. In order to make the SPR detection of magnetic field and temperature effectively, the two open ring channels of the proposed sensor are coated with gold and silver layers and filled with magnetic fluid (MF) and Polydimethylsiloxane (PDMS), respectively. The sensor is analyzed by the finite element method and its mode characteristics, structure parameters and sensing performance are investigated. The analysis reveals when the magnetic field is a range of 40-310 Oe and the temperature is a range of 0-60 °C, the maximum magnetic field sensitivity is 308.3 pm/Oe and temperature sensitivity is 6520 pm/°C. Furthermore, temperature and magnetic field do not crosstalk with each other's SPR peak. Its refractive index sensing performance is also investigated, the maximum sensitivity and FOM of the left channel sensing are 16820 nm/RIU and 1605 RIU-1, that of the right channel sensing are 13320 nm/RIU and 2277 RIU-1. Because of its high sensitivity and special sensing performance, the proposed sensor will have potential application in solving the problems of cross-sensitivity and demodulation due to nonlinear changes in sensitivity of dual-parameter sensing.

This paper presents a graphene metamaterial absorber based on impedance matching. A finite difference in time domain (FDTD) method is used to achieve a theoretically perfect absorption in the mid-infrared band. A basis is created for the multiband stable high absorption of graphene in the mid-infrared. The designed graphene absorber is composed of graphene, a dielectric layer, a gold plane, and a silicon substrate, separately. The incident source of mid-infrared can be utilized to stimulate multiband resonance absorption peaks from 2.55 to 4.15 μm. The simulation results show that the absorber has three perfect resonance peaks exceeding 99% at λ1 = 2.67 μm, λ2 = 2.87 μm, and λ3 = 3.68 μm, which achieve an absorption efficiency of 99.67%, 99.61%, and 99.40%, respectively. Furthermore, the absorber maintains an excellent performance with a wide incident angle range of 0°–45°, and it also keeps the insensitive characteristic to transverse electric wave (TE) and transverse magnetic wave (TM). The results above indicate that our perfect graphene absorber, with its tunability and wide adaptability, has many potential applications in the fields of biosensing, photodetection, and photocell.

Non-diffracting beam are attracting increased attention because of their unique characteristics. A non-diffracting beam is usually generated with an axicon, which is a kind of line focus optical element with a conical surface axis that rotates symmetrically. Three deviation models of a generatrix relative to the ideal axicon have been established on its processing technology, namely, concave to the inner side, convex to the outer side and hyperbolic distribution of the apex of the axicon. The amplitude transmittance function is derived based on the profile of the generatrix. The emergent light field and intensity distributions of the three kinds of axicon in the case of plane wave verticality illumination are analyzed and simulated according to the Fresnel diffraction theory. Moreover, the theory of axicon diffraction field is enriched and the guiding significance for the processing of axicon lens is increased.

Nanostructured transition metal oxide anodes have attracted considerable attention for high-performance lithium-ion batteries (LIBs). However, their low rate capability and rapid capacity decline resulting from their low electronic conductivities and inevitable substantial volumetric changes prevent them from being commercialized as anodes for LIBs. Herein, we design a high-performance anode for LIBs consisting of a yolk–shell structured Fe2O3@C nanoring (NR) composite that comprises a NR-like Fe2O3 core entirely protected by a fine porous carbon (C) shell to overcome such obstacles. This advantageous yolk–shell structural design can buffer the significant volume variations of Fe2O3 cores without damaging the microstructure of the electrode. Thanks to the unique structural features, the as-built electrode shows a remarkable electrochemical performance, namely, a large specific capacity of 846 mA h g−1 after 100 cycles at 0.2 A g−1, a superior rate performance of 688 mA h g−1 at 4 A g−1, and a remarkable cycling life (300 cycles, 945 mA h g−1 at 4.0 A g−1). Hence, this electrode is much better than a pure Fe2O3 NR electrode.

Metamaterials refers to a class of artificial materials with special properties. Through its unique geometry and the small size of each unit, the material can acquire unique electromagnetic field properties that conventional materials do not have. Based on these factors, we put forward a kind of high absorption near-ultraviolet to near-infrared electromagnetic wave absorber of the solar energy. The surface structure of the designed absorber is composed of TiN-TiO2-Al2O3 with rectangles and disks, and the substrate is Ti-Al2O3-Ti layer. In the study band range (0.1–3.0 μm), the solar absorber’s average absorption is up to 96.32%, and the designed absorber absorbs more than 90% of the electromagnetic wave with a wavelength width of 2.577 μm (0.413–2.990 μm). Meanwhile, the designed solar absorber has good performance under different angles of oblique incident light. Ultra-wideband solar absorbers have great potential in light absorption related applicaitions because of their wide spectrum high absorption properites.

A matching factor-based morphological recognition method for centering a concentric circle fringe image under complex background was proposed. The basic principle is that the amplitude of phase fluctuation along with the matching factor, which is proportional to the deviation from the center of the non-diffracting spot. The cross section of non-diffracting beam which consist of concentric circle fringe, is first obtained from a matrix array image sensor, downloaded into a computer, and then, the approximate central spot position of concentric circle is calculated by finding the position of the peak value of the dimensionless matching factor. Because all the intensity distribution information of the non-diffracting beam is used for the calculation from image recognition of gray scale, the effect of background noise on centering is significantly reduced and the center position resolution can achieve subpixel accuracy. The measurement of the spatial angle is discussed which shows great advancement and application prospect in the orientation system of tunneling equipment.

Mussel-inspired polydopamine (PDA) coating is a promising avenue for surface modification. However, the reported methods for PDA deposition require alkaline media, strong oxidation reagents or UV light irradiation. Herein, we report a facile and mild method to prepare PDA in the presence of 9-mesityl-10-methylacridinium ions (Acr+-Mes) as the photocatalyst under visible-light irradiation. The excited-state Acr+-Mes with a high oxidation property and its intermediate which can activate dissolved oxygen enable the oxidation polymerization of dopamine in a neutral environment (pH = 7.0). This approach is easily controlled by switching the visible light (ON/OFF possibility), which can be used to coat several substrates such as polystyrene foam, filter paper, aluminium foil, and glass as well as improve their hydrophilicity. In addition, a visual colorimetric assay is developed for detection of bovine serum albumin. This assay is based on the fact that protein with diverse functional groups serves as the anchor point for PDA deposition that further promotes the oxidation of dopamine, giving rise to a distinct UV-vis absorption change.

In this paper we examined both theoretically and experimentally the diffraction field along the axis of propagation of the zero order Bessel distribution produced by an axicon. An axicon is typically used to obtain quasi non-diffracting beams. We found that an Arago-Poisson diffraction spot, normally only observed behind an opaque circular obstacle, can also be observed in the shadow area of an axicon lens. Both theoretical and experimental analysis indicate that the intensity distribution of the diffraction spot follows a zero order Bessel function in the paraxial region. The diffraction spot diameter increases linearly with the propagation distance in the shadow area while its energy decreases with propagation distance. The illuminated region and Arago-Poisson diffraction spot never overlap because the diameters of either increase linearly with propagation distance. Therefore, in theory, the Arago-Poisson diffraction spot could propagate to infinity. Our observation may be useful to produce an accurate straight line reference in commercial alignment systems.

A polar transformation-based phase-scanning method for centering a concentric circle fringe image is proposed. The basic principle is that the amplitude of phase-fluctuation, along with the polar angle, is proportional to the deviation from the center of the non-diffracting spot. The minimum of such amplitude appears in the position of the ideal center. The image of a non-diffracting beam, the cross section of which is a concentric circle fringe, is first recorded by a matrix array image sensor, downloaded to a computer, and then expanded into polar grayscale in the initial position. We contrast the phase of a standard sine pattern produced by a computer with the polar grayscale along with the polar angle through the principle of phase-scanning to obtain the phase fluctuation for the non-diffracting beam along with the polar angle. The common center of the non-diffracting image is then calculated by searching for the position of the phase amplitude minimum. The effect of background noise and non-circular fringe on centering is significantly reduced, and the center position resolution can still reach the order of a charge-coupled device in a complex background because all the intact data on the non-diffracting image are used in the calculation.

A probe technique based on non-diffracting beam was proposed. The probe was combined with a total station or a laser tracker to form a combined measuring system that realized the coordinate measurement of hidden parts in large spaces. In the combined measurement system, the probe stylus was first set to touch the point of measurement, and the optical system of the probe was targeted by the total station or the laser tracker. This was used to measure the spatial coordinates of the probe. The probe transformed the laser that was used to measure distance into a non-diffracting beam through the axicon lens, and non-diffracting images were produced in CCD plane. The center of the non-diffracting beam mapped one to one to the incident direction of the laser, and the horizontal angle the probe were obtained via center fitting of the non-diffracting images. The inclinometer was used to measure the rolling angle and the pitching angle of the probe. Finally, all the measured attitude angles and position coordinates were combined and coordinate transformation was used to calculate the spatial coordinates of the measured point. Our results show that the probe could achieve milliradian-level precision when measuring the attitude angles, demonstrating more flexibility and reliable precision during combined measurement.

An electronic target technology based on a nondiffracting beam for spatial attitude determination is proposed. Automatic orientation of shield tunnel equipment is achieved by a spatial-coordinates measurement system consisting of an electronic target and a total station. During the measurement, a ranging laser beam is sent from the total station. It is transformed into a nondiffracting beam by an axicon, and the beam spot images are captured by a charged-coupled device image sensor. Since the center of the nondiffracting beam has a one-to-one mapping to the incident direction of the laser, the spatial orientation of the laser beam can be obtained via center fitting of the nondiffracting images. When this system is combined with a two-dimensional electronic inclinometer, the attitude parameters can be determined from the relationship of different spatial angles. Experimental results demonstrate that the attitude measurement system has a precision of ±0.5 mrad. Further, the engineering applications also show that the system has high operational quality and environmental adaptability.