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2,279 results on '"Guo, Zhiyong"'

6. Intermarriage and ancient polity alliances: isotopic evidence of cross-regional female exogamy during the Longshan period (2500-1900 BC)

Author

Wu, Xiaotong, Guo, Zhiyong, He, Nu, Zhao, Shijie, Li, Yanxin, Yu, Huimin, Huang, Fang, and Zhang, Xingxiang

Subjects
Endogamy and exogamy -- Analysis, Anthropological research, Social networks -- Analysis, Enamel, Dental -- Analysis, Anthropology/archeology/folklore
Abstract

The late third-millennium BC Longshan period was a crucial time for state formation in central China. During these centuries, long-distance networks expanded and shared material culture and then cultural practices spread across wider areas precipitating social and ideological developments that presaged the rise of states and cities on the Central Plain. In this research, the authors use multiple (strontium, oxygen and carbon) isotope analyses from the dental enamel of 67 individuals buried at the Xiajin cemetery, Shanxi Province. The results indicate significant long-distance migration among females during the Longshan period, which the authors interpret as evidence of exogamous marriage for political alliance-building--a phenomenon found more widely across Eurasia at the start of the Bronze Age. Keywords: central China, Neolithic, Bronze Age, Taosi culture, burial, isotopic analysis, migration, exogamy, Introduction The Longshan period (c. 2500-1900 BC) was a crucial time for state formation in central China. During this period, inter-regional networks developed rapidly, transmitting shared material forms and cultural [...]

Published
2024
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10. Nanoparticles Passive Targeting Allows Optical Imaging of Bone Diseases

Author

Mi, Chao, Zhang, Xun, Yang, Chengyu, Wu, Jianqun, Chen, Xinxin, Ma, Chenguang, Wu, Sitong, Yang, Zhichao, Qiao, Pengzhen, Liu, Yang, Wu, Weijie, Guo, Zhiyong, Liao, Jiayan, Zhou, Jiajia, Guan, Ming, Liang, Chao, Liu, Chao, and Jin, Dayong

Subjects
Physics - Biological Physics, Physics - Medical Physics, Physics - Optics
Abstract

Bone health related skeletal disorders are commonly diagnosed by X-ray imaging, but the radiation limits its use. Light excitation and optical imaging through the near-infrared-II window (NIR-II, 1000-1700 nm) can penetrate deep tissues without radiation risk, but the targeting of contrast agent is non-specific. Here, we report that lanthanide-doped nanocrystals can be passively transported by endothelial cells and macrophages from the blood vessels into bone marrow microenvironment. We found that this passive targeting scheme can be effective for longer than two months. We therefore developed an intravital 3D and high-resolution planar imaging instrumentation for bone disease diagnosis. We demonstrated the regular monitoring of 1 mm bone defects for over 10 days, with resolution similar to X-ray imaging result, but more flexible use in prognosis. Moreover, the passive targeting can be used to reveal the early onset inflammation at the joints as the synovitis in the early stage of rheumatoid arthritis. Furthermore, the proposed method is comparable to {\mu}CT in recognizing symptoms of osteoarthritis, including the mild hyperostosis in femur which is ~100 {\mu}m thicker than normal, and the growth of millimeter-scale osteophyte in the knee joint, which further proves the power and universality of our approach in diagnosis of bone diseases

Published
2023

11. An MPI-based parallel genetic algorithm for multiple geographical feature label placement based on the hybrid of fixed-sliding models

Author

Lessani, Mohammad Naser, Li, Zhenlong, Deng, Jiqiu, and Guo, Zhiyong

Subjects
Computer Science - Distributed, Parallel, and Cluster Computing
Abstract

Multiple geographical feature label placement (MGFLP) has been a fundamental problem in geographic information visualization for decades. The nature of label positioning is proven an NP-hard problem, where the complexity of such a problem is directly influenced by the volume of input datasets. Advances in computer technology and robust approaches have addressed the problem of labeling. However, what is less considered in recent studies is the computational complexity of MGFLP, which significantly decreases the adoptability of those recently introduced approaches. In this study, an MPI parallel genetic algorithm is proposed for MGFLP based on a hybrid of fixed position model and sliding model to label fixed-types of geographical features. To evaluate the quality of label placement, a quality function is defined based on four quality metrics, label-feature conflict, label-label conflict, label ambiguity factor, and label position priority for points and polygons. Experimental results reveal that the proposed algorithm significantly reduced the overall score of the quality function and the computational time of label placement compared to the previous studies. The algorithm achieves a result in less than one minute with 6 label-feature conflicts, while Parallel-MS (Lessani et al., 2021) obtains the result in more than 20 minutes with 12 label-feature conflicts for the same dataset., Comment: 35 Pages, 11 Figures

Published
2022

15. High Spatial and Temporal Resolution NIR-IIb Gastrointestinal Imaging in Mice

Author

Mi, Chao, Guan, Ming, Zhang, Xun, Yang, Liu, Wu, Sitong, Yang, Zhichao, Guo, Zhiyong, Liao, Jiayan, Zhou, Jiajia, Jin, Dayong, and Yuan, Xiaocong

Subjects
Physics - Medical Physics, Physics - Optics
Abstract

Conventional biomedical imaging modalities, including endoscopy, X-rays, and magnetic resonance, are invasive and cannot provide sufficient spatial and temporal resolutions for regular imaging of gastrointestinal (GI) tract to guide prognosis and therapy of GI diseases. Here we report a non-invasive method for optical imaging of GI tract. It is based on a new type of lanthanide-doped nanocrystal with near-infrared (NIR) excitation at 980 nm and second NIR window (NIR-IIb) (1500~1700 nm) fluorescence emission at around 1530 nm. The rational design and controlled synthesis of nanocrystals with high brightness have led to an absolute quantum yield (QY) up to 48.6%. Further benefitting from the minimized scattering through the NIR-IIb window, we enhanced the spatial resolution by 3 times compared with the other NIR-IIa (1000~1500 nm) contract agents for GI tract imaging. The approach also led to a high temporal resolution of 8 frames per second, so that the moment of mice intestinal peristalsis happened in one minute can be captured. Furthermore, with a light-sheet imaging system, we demonstrated a three-dimensional (3D) imaging of the stereoscopic structure of the GI tract. Moreover, we successfully translate these advances to diagnose inflammatory bowel disease (IBD) in a pre-clinical model of mice colitis.

Published
2022
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18. Pretransplant use of immune checkpoint inhibitors for hepatocellular carcinoma: A multicenter, retrospective cohort study

Author

Guo, Zhiyong, Liu, Yao, Ling, Qi, Xu, Leibo, Wang, Tielong, Zhu, Jiaxing, Lin, Yimou, Lu, Xinjun, Qu, Wei, Zhang, Fan, Zhu, Zhijun, Zhang, Jian, Jia, Zehua, Zeng, Ping, Wang, Wenjing, Sun, Qiang, Luo, Qijie, Hu, Zemin, Zheng, Zhouying, Jia, Yingbin, Li, Jian, Zheng, Yujian, Wang, Mengchao, Wang, Shaoping, Han, Zemin, Yu, Sheng, Li, Chuanjiang, Zhang, Shuhua, Xiong, Jun, Deng, Feiwen, Liu, Ying, Chen, Huanwei, Wang, Yanfeng, Li, Ling, Liang, Wenjin, Schlegel, Andrea, Nashan, Björn, Liu, Chao, Zheng, Shusen, and He, Xiaoshun

Published
2024
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