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Your search keyword '"Gunther, Jacqueline E."' showing total 26 results
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26 results on '"Gunther, Jacqueline E."'

3. Online learning combining virtual lectures, at-home experiments and computer simulations: a multidisciplinary teaching and learning approach

Author

Nogueira, Marcelo S., primary, Komolibus, Katarzyna, additional, Gunther, Jacqueline E., additional, Konugolu, Sanathana, additional, Sekar, Venkata, additional, Jayet, Baptiste, additional, Tobo, Andrea L., additional, Li, Celina L., additional, Maryam, Siddra, additional, Tyndall, Caitriona, additional, and Kennedy, Declan, additional

Published
2022
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5. Multidisciplinary teaching and learning biophotonics: assessing the effectiveness of fully online outreach events

Author

Saito Nogueira, Marcelo, primary, Li, Celina L., additional, Maryam, Siddra, additional, Tyndall, Caitriona, additional, Donovan, Sarah, additional, Komolibus, Katarzyna, additional, Gunther, Jacqueline E., additional, Venkata Sekar, Sanathana Konugolu, additional, Jayet, Baptiste, additional, Fisher, Carl, additional, Kennedy, Declan, additional, and Andersson-Engels, Stefan, additional

Published
2022
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6. Accurate colorectal cancer detection and delineation by probing superficial and deeper tissue biochemistry and microstructure using diffuse reflectance spectroscopy

Author

Saito Nogueira, Marcelo, primary, Raju, Michael, additional, Gunther, Jacqueline E., additional, Maryam, Siddra, additional, Amissah, Michael, additional, Killeen, Shane, additional, Lu, Huihui, additional, O’Riordain, Micheal, additional, and Andersson-Engels, Stefan, additional

Published
2022
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11. Dynamic Diffuse Optical Tomography for Monitoring Neoadjuvant Chemotherapy in Patients with Breast Cancer

Author

Gunther, Jacqueline E., primary, Lim, Emerson A., additional, Kim, Hyun K., additional, Flexman, Molly, additional, Altoé, Mirella, additional, Campbell, Jessica A., additional, Hibshoosh, Hanina, additional, Crew, Katherine D., additional, Kalinsky, Kevin, additional, Hershman, Dawn L., additional, and Hielscher, Andreas H., additional

Published
2018
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13. Neoadjuvant Chemotherapy Monitoring of Breast Cancer Patients with Diffuse Optical Tomographic Imaging

Author

Gunther, Jacqueline E.

Subjects
Cancer--Chemotherapy, Breast--Cancer, Breast--Cancer--Treatment, Diagnostic imaging, Biomedical engineering
Abstract

The overall goal of this thesis was to determine whether optical tomographic imaging can be employed to predict treatment outcome in women with breast cancer (BC) who undergo neoadjuvant chemotherapy (NACT). NACT is widely applied as a standard treatment for patients with newly diagnosed operable invasive BC. Only about 13-30% of women have a response to this treatment. Furthermore, NACT is an expensive and toxic treatment that takes several months to completely administer. In order to know the response of the patient, physicians usually need to wait until the months of NACT has finished and the patient has undergo surgery in which they receive the pathology. If the long-term treatment response could be predicted early into the treatment regimen, the patient would be relieved of any unnecessary side effects and alternative treatments could be initiated. We have used a novel dynamic DOT system to study the effects of targeted NACT. Unlike X-ray imaging, which requires potentially harmful ionizing radiation, DOT can be applied without side effects, which is particularly important in the case of multiple imaging sessions to be performed over the course of treatment. We have tracked 40 subjects and imaged them at 6 different time points during their NACT. For this study, two different types of data were collected: static (single 3D image) and dynamic (3D movies). The combination of the data may be used to accurately determine the response of the patient. With non-invasive, non-ionizing DOT imaging we have been able to determine within two weeks if the patient will respond to treatment with an accuracy as high as 94.1%.

Published
2016
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14. Baseline oxygen saturation comparison between pathologic complete responders and extensive residual cancer cases in response to neoadjuvant chemotherapy

Author

Altoe, Mirella L., additional, Gunther, Jacqueline E., additional, Lim, Emerson, additional, Kim, Hyun Keol, additional, Campbell, Jessica, additional, Hibshoosh, Hanina, additional, Crew, Katherine, additional, Kalinsky, Kevin, additional, Hershman, Dawn L., additional, and Hielscher, Andreas H., additional

Published
2017
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17. Abstract P5-01-05: Early optical tomography changes correlate with residual cancer burden scores in women receiving neoadjuvant chemotherapy

Author

Lim, Emerson A, primary, Gunther, Jacqueline E, additional, Flexman, Molly, additional, Kim, Hyun K, additional, Hibshoosh, Hanina, additional, Kalinsky, Kevin, additional, Crew, Katherine, additional, Maurer, Matthew, additional, Feldman, Sheldon, additional, Taback, Bret, additional, Ananthakrishnan, Preya, additional, Chen, Margaret, additional, Refice, Susan, additional, Hielscher, Andreas, additional, and Hershman, Dawn L, additional

Published
2015
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