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125 results on '"Gunawardane, Ruwanthi N."'

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1. Automated human induced pluripotent stem cell culture and sample preparation for 3D live-cell microscopy

2. Integrated intracellular organization and its variations in human iPS cells

3. Enhanced endogenous gene tagging in human induced pluripotent stem cells via AAV6-mediated donor delivery

4. A comprehensive analysis of gene expression changes in a high replicate and open-source dataset of differentiating hiPSC-derived cardiomyocytes

5. Incomplete-penetrant hypertrophic cardiomyopathy MYH7 G256E mutation causes hypercontractility and elevated mitochondrial respiration.

6. Automated human induced pluripotent stem cell culture and sample preparation for 3D live-cell microscopy

10. Multi-scale models reveal hypertrophic cardiomyopathy MYH7 G256E mutation drives hypercontractility and elevated mitochondrial respiration

13. Data from CEP-32496: A Novel Orally Active BRAFV600E Inhibitor with Selective Cellular and In Vivo Antitumor Activity

15. Supplementary Data 1 from CEP-32496: A Novel Orally Active BRAFV600E Inhibitor with Selective Cellular and In Vivo Antitumor Activity

20. Multi-scale models reveal hypertrophic cardiomyopathy MYH7 G256E mutation drives hypercontractility and elevated mitochondrial respiration

22. MYC Regulation of a "Poor-Prognosis" Metastatic Cancer Cell State

24. Cell states beyond transcriptomics: Integrating structural organization and gene expression in hiPSC-derived cardiomyocytes

25. A comprehensive analysis of gene expression changes in a high replicate and open-source dataset of differentiating hiPSC-derived cardiomyocytes

26. Automated hiPSC culture and sample preparation for 3D live cell microscopy

27. Cell states beyond transcriptomics: integrating structural organization and gene expression in hiPSC-derived cardiomyocytes

28. Xgrip109: a gamma tubulin-associated protein with an essential role in gamma tubulin ring complex (gamma-TuRC) assembly and centrosome function

31. Fluorescent Gene Tagging of Transcriptionally Silent Genes in hiPSCs

33. Scarless gene tagging of transcriptionally silent genes in hiPSCs to visualize cardiomyocyte sarcomeres in live cells

34. Systematic gene tagging using CRISPR/Cas9 in human stem cells to illuminate cell organization

35. Characterization and Reconstitution of Drosophila [Gamma]-Tubulin Ring Complex Subunits

36. Agonistic Human Antibodies Binding to Lecithin-Cholesterol Acyltransferase Modulate High Density Lipoprotein Metabolism

37. The high-resolution crystal structure of human LCAT

38. MYC regulation of a 'poor-prognosis' metastatic cancer cell state

39. 4-Quinazolinyloxy-diaryl ureas as novel BRAFV600E inhibitors

41. CEP-32496: A Novel Orally Active BRAFV600E Inhibitor with Selective Cellular and In Vivo Antitumor Activity

42. Discovery of Highly Potent and Selective Pan-Aurora Kinase Inhibitors with Enhanced in Vivo Antitumor Therapeutic Index

43. Identification of 1-(3-(6,7-Dimethoxyquinazolin-4-yloxy)phenyl)-3-(5-(1,1,1-trifluoro-2-methylpropan-2-yl)isoxazol-3-yl)urea Hydrochloride (CEP-32496), a Highly Potent and Orally Efficacious Inhibitor of V-RAF Murine Sarcoma Viral Oncogene Homologue B1 (BRAF) V600E

44. Abstract 3300: MYC regulation of a “poor prognosis” metastatic cancer cell state

45. AC220, a Potent, Selective, Second Generation FLT3 Receptor Tyrosine Kinase (RTK) Inhibitor, in a First-in-Human (FIH) Phase 1 AML Study.

46. Identification of N-(5-tert-Butyl-isoxazol-3-yl)-N′-{4-[7-(2-morpholin-4-yl-ethoxy)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl}urea Dihydrochloride (AC220), a Uniquely Potent, Selective, and Efficacious FMS-Like Tyrosine Kinase-3 (FLT3) Inhibitor

48. Functional Proteomics Approach to Investigate the Biological Activities of cDNAs Implicated in Breast Cancer

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