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Edward Leicester Atkinson qualified at St Thomas's Hospital in 1906 and joined the Navy in 1908. He was a doctor and parasitologist on Captain Scott's Terra Nova expedition to the Antarctic and had to take charge of the expedition when Scott died on his return from the South Pole. After the expedition he went to China and discovered the cause of schistosomiasis, returning at the start of the First World War in which he served with distinction, winning a DSO and Albert Medal but also being severely injured. After the war he served in various naval posts and became the youngest Surgeon Captain in the Navy before being retired on health grounds in 1928. He died at sea the following year. [ABSTRACT FROM AUTHOR]

Background Raised blood pressure (and heart rate (HR)) due to anxiety in a clinical situation is well described and is called the white coat effect (WCE). It is not known whether the pain and anxiety that results from trauma causes a measurable WCE. Methods A sample of patients with a nonhaemorrhagic injury from the Trauma Audit and Research Network (TARN) was compared with a healthy, non-injury sample from the Health Survey for England (HSE) databases. Two-way analysis of variance with rank transformation of data was used to compare systolic blood pressure (SBP) and HR between the groups at different ages. In the injured group, the SBP and HR were also compared between spinally immobilised and non-immobilised patients. Results There was a statistically significant difference between the groups for both HR and SBP ( p<0.001). Median HR remained approximately 10 bpm higher in the TARN set when compared to the HSE set, irrespective of age. The difference for SBP was not considered clinically relevant (the highest was 5 mm Hg). There was no significant difference between immobilised and nonimmobilised patients, for either HR or SBP (p=0.07 and 0.3, respectively). Discussion Median HR remained approximately 10 bpm higher in the TARN (injury) set compared to the HSE (non-injury, control) set, irrespective of age. Understanding that HR reacts in this way for mild to moderately injured patients is important as it will affect clinical interpretation during the initial assessment. [ABSTRACT FROM AUTHOR]

At the start of the heroic age of Antarctic exploration there was great confusion concerning the cause of scurvy. It was known that it was related, in some way, to food but it was uncertain as to how, and there were two main theories. The first was that it was caused by a deficiency of fruit and vegetables and the other that it was caused by a toxic material in tinned foods. In addition, older theories that it was caused by dirt and damp still carried weight and Almroth Wright had proposed that scurvy was caused by too much acid in the blood. An additional confusion was that vitamin C deficiency was often combined with other vitamin deficiencies and so other diseases might be labelled as scurvy. The discovery of vitamins occurred over the same period but, as with all new scientific concepts, the knowledge that scurvy was caused by a vitamin deficiency took time to be universally accepted. It was generally accepted by about 1920, although some people did not accept it until vitamin C has been isolated in 1932. [ABSTRACT FROM PUBLISHER]