396 results on '"Guitton C"'
Search Results
2. Place de l’oxygénothérapie haut débit dans la pré-oxygénation pour l’intubation et la pratique des gestes invasifs
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Meunier, J. and Guitton, C.
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- 2023
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3. Allogreffe de cellules souches hématopoïétiques chez les patients adolescents et adultes atteints de drépanocytose
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Dhédin, N., primary, Vasseur, L., additional, Chevillon, F., additional, Jestin, M., additional, Flamarion, E., additional, Kamden, A., additional, Arnaud, C., additional, Genty, I., additional, Parquet, N., additional, Guitton, C., additional, Brignier, A., additional, Michaud, K., additional, Michaux, K., additional, Lagarde, M., additional, Peffault De Latour, R., additional, Bernit, E., additional, Boissel, N., additional, Arlet, J.B., additional, and Pondarré, C., additional
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- 2023
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4. Impact of Centre of Admission on Receipt of ECMO among Patients with Hypoxemic Respiratory Failure: A Secondary Analysis of the LUNG SAFE and REVA Influenza A(H1N1) Studies
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Tillmann, Bourke W., primary, Pham, Tai, additional, Scales, Damon C., additional, Fan, Eddy, additional, Pinto, Ruxandra, additional, Rubenfeld, Gordon, additional, Rios, Fernando, additional, Van Haren, Frank, additional, T, Sottiaux, additional, P, Depuydt, additional, Lora, Fredy S., additional, Azevedo, Luciano Cesar, additional, Bugedo, Guillermo, additional, Qiu, Haibo, additional, Gonzalez, Marcos, additional, Silesky, Juan, additional, Cerny, Vladimir, additional, Nielsen, Jonas, additional, Jibaja, Manuel, additional, Pham, Tài, additional, Wrigge, Hermann, additional, Matamis, Dimitrios, additional, Ranero, Jorge Luis, additional, Amin, Pravin, additional, Hashemian, S.M., additional, Clarkson, Kevin, additional, Bellani, Giacomo, additional, Kurahashi, Kiyoyasu, additional, Villagomez, Asisclo, additional, Zeggwagh, Amine Ali, additional, Heunks, Leo M., additional, Laake, Jon Henrik, additional, Palo, Jose Emmanuel, additional, Fernandes, Antero do Vale, additional, Sandesc, Dorel, additional, Arabi, Yaasen, additional, Bumbasierevic, Vesna, additional, Nin, Nicolas, additional, Lorente, Jose A., additional, Larsson, Anders, additional, Piquilloud, Lise, additional, Abroug, Fekri, additional, McAuley, Daniel F., additional, McNamee, Lia, additional, Hurtado, Javier, additional, Bajwa, Ed, additional, Démpaire, Gabriel, additional, Zogheib, E., additional, Dupont, H., additional, Mercat, A., additional, Pierrot, M., additional, Capellier, G., additional, Verdiere, B., additional, Bastien, O., additional, Lehot, J.-J., additional, Tonnelier, J.M., additional, Guelon, D., additional, du Cheyron, D., additional, Thille, A., additional, Pham, T., additional, Brun-Buisson, C., additional, Quenot, J.-P., additional, Arasomoano, C., additional, Minet, C., additional, Timsit, J.-F., additional, Dessertaine, G., additional, Robriquet, L., additional, Jaillette, E., additional, Castanier, M., additional, Roch, A., additional, Papazian, L., additional, Eliet, J., additional, Gaudard, P., additional, Machado, S., additional, Kuteifan, K., additional, Kimmoun, A., additional, Levy, B., additional, Bizouarn, P., additional, Villiers, D., additional, Guitton, C., additional, Dellamonica, J., additional, Boulain, T., additional, Mourvillier, B., additional, Salin, J. Bailly, additional, Wolff, M., additional, Charpentier, J., additional, Chiche, J.-D., additional, Ricome, S., additional, Megarbane, B., additional, Combes, A., additional, Schmidt, M., additional, Bréchot, N., additional, Chastre, J., additional, Rozé, H., additional, Ouattara, A., additional, Robert, R., additional, Carise, E., additional, Reignier, J., additional, Beduneau, G., additional, Richard, J.-C.M., additional, Le Tulzo, Y., additional, Zeni, F., additional, Jospe, R., additional, Kummerlen, C., additional, Gouello, J.P., additional, Cerf, C., additional, Devaquet, J., additional, Riu-Poulenc, B., additional, Luzi, A., additional, Georges, B., additional, Mayeur, N., additional, Mercier, E., additional, Guillon, A., additional, and Eustache, M.L., additional
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- 2023
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5. Prise en charge pratique des complications aiguës de la drépanocytose chez l’enfant
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Pondarré, C., Guitton, C., Hau, I., Ngo, J., and Thuret, I.
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- 2018
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6. Intubation and extubation of the ICU patient
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Quintard, H., l’Her, E., Pottecher, J., Adnet, F., Constantin, J.-M., De Jong, A., Diemunsch, P., Fesseau, R., Freynet, A., Girault, C., Guitton, C., Hamonic, Y., Maury, E., Mekontso-Dessap, A., Michel, F., Nolent, P., Perbet, S., Prat, G., Roquilly, A., Tazarourte, K., Terzi, N., Thille, A.W., Alves, M., Gayat, E., and Donetti, L.
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- 2017
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7. Analyse des représentations du couchage des nourrissons
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Guitton, C., Bouin, T., and Oriot, D.
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- 2017
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8. Intérêt de l’échographie pulmonaire dans le diagnostic et la détection précoce du syndrome thoracique aigu chez l’enfant drépanocytaire hospitalisé pour crise vaso-occlusive : résultats intermédiaires de l’étude Echo-STA
- Author
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Delestrain, C., primary, Odièvre, M.H., additional, Guitton, C., additional, Thouvenin, G., additional, Berdah, L., additional, Prevost, B., additional, El Jurdi, H., additional, Gajdos, V., additional, Epaud, R., additional, Pondarré, C., additional, Arnaud, C., additional, and Madhi, F., additional
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- 2023
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9. Recommandations d’utilisation des agonistes du récepteur de la thrombopoïétine dans le purpura thrombopénique immunologique de l’enfant et de l’adolescent
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Pasquet, M., Aladjidi, N., Guitton, C., Leblanc, T., Pérel, Y., and Leverger, G.
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- 2015
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10. Hémorragie intracrânienne compliquant un purpura thrombopénique immunologique aigu de l’enfant : une étude rétrospective nationale
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Sevrez, C., Thouvenin, S., Choppard, B., Fouyssac, F., Baleydier, F., Chambost, H., Demeocq, F., Plantaz, D., Girard, P., Guitton, C., Boutmy, A., Lescoeur, B., Abouchahla, W., Derache, A.F., Leverger, G., Aladjidi, N., and Stephan, J.L.
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- 2014
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11. Recessive mutations in NDUFA2 cause mitochondrial leukoencephalopathy
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Perrier, S., Gauquelin, L., Tétreault, M., Tran, L.T., Webb, N., Srour, M., Mitchell, J.J., Brunel‐Guitton, C., Majewski, J., Long, V., Keller, S., Gambello, M.J., Simons, C., Vanderver, A., and Bernard, G.
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- 2018
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12. La crise drépanocytaire : une urgence douloureuse
- Author
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Guitton, C. and Fournier-Charrière, E.
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- 2012
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13. Facteurs de risque de COVID-19 sévère chez des patients drépanocytaires hospitalisés : étude nationale Française chez 319 patients
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Arlet, J.B., primary, Lionnet, F., additional, Khimoud, D., additional, Joseph, L., additional, De Montalembert, M., additional, Garou, A., additional, Cannas, G., additional, Cougoul, P., additional, Guitton, C., additional, Holvoet, L., additional, Odièvre, M.H., additional, Cheminet, G., additional, Bartolucci, P., additional, Santin, A., additional, Bernit, E., additional, and De Luna, G., additional
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- 2021
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14. Caractéristiques des patients drépanocytaires infectés par le SARS-CoV-2 en fonction de leur prise en charge ambulatoire ou en hospitalisation : étude nationale chez 536 patients
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Arlet, J.B., primary, De Luna, G., additional, Khimoud, D., additional, Cheminet, G., additional, Garou, A., additional, Cannas, G., additional, Cougoul, P., additional, Guitton, C., additional, Holvoet, L., additional, Odièvre, M.H., additional, Joseph, L., additional, Santin, A., additional, De Montalembert, M., additional, Bartolucci, P., additional, Bernit, E., additional, and Lionnet, F., additional
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- 2021
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15. 1st Conference Clinical Trials on Alzheimer’s Disease September 17-18-19, 2008 School of Medecine Montpellier, France
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Gabelle, A., Roche, S., Gény, C., Portet, F., Touchon, J., Lehmann, S., De Meyer, G., Shapiro, F., Vanderstichele, H., Vanmechelen, E., Engelborghs, S., De Deyn, P. P., Shaw, L., Trojanowski, J., Nestor, S. M., Rupsingh, R., Borrie, M., Smith, M., Wells, J. L., Bartha, R., Blennow, K., De Meyer, G., Hansson, O., Minthon, L., Wallin, A., Zetterberg, H., Lewezuk, P., Vandertischele, H., Kornhuber, J., Wiltfang, J., Iqbal, K., Chalbot, S., Grundke-Iqbal, I., Gertz, H. J., Berwig, M., Leicht, H., Zhu, C. W., Leibman, C., Townsend, R., Mclaughlin, T., Scarmeas, N., Albert, M., Brandt, J., Blacker, D., Sano, M., Stern, Y., Bravo, G., Dubois, M. F., Hansel, S., Duguet, A. M., Robert, P. H., Deudon, A., Ake, N., Gervais, X., Leone, E., Lavallart, B., Amato, D., Zavitz, K., Green, R. C., Schneider, L. S., Swabb, E., Van Kan, G. Abellan, Carrie, I., Gillette, S., Soto, M. E., Gardette, J., Przybylski, C., Andrieu, S., Vellas, B., Dangour, A. D., Allen, E., Elbourne, D., Fletcher, A., Richards, M., Uauy, R., Green, R. C., Schneider, L. S., Zavitz, K. H., Wurtman, R. J., Peters, O., Lorenz, D., Möller, H. J., Frölich, L., Heuser, I., Vandenberghe, R., Thurfjell, L., Owenius, R., Brooks, D. J., Nelissen, N., Koole, M., Bormans, G., Van Laere, K., Boada, M., Muñoz, J., Tárraga, L., Ortiz, P., Hernández, I., Becker, J., López, O., Buendia, M., Pla, R., Grifols, J. R., Paez, A., Núñez, L., Ferrer, I., Lachno, D. R., De Groote, G., Kostanjevecki, V., Siemers, E. R., Willey, M. B., Ruiz, A., Ramírez-Lorca, R., Sáez, M. E., Mauleón, A., Rosende-Roca, M., Martínez-Lage, P., Gutiérrez, M., Real, L. Miguel, López-arrieta, J., Gayán, J., Antúnez, C., González-Pérez, A., Hugonot-Diener, L., Bchiri, J. El, Fraisse, M. L., Von Raison, F., Bone, M., Duron, E., Husson, J. M., Meeuwsen, E. J., Melis, R. J. F., Adang, E. M., Krabbe, P. F., Schölzel-Dorenbos, C. J. M., Ruckert, M. G. M. Olde, Truemner, J., Best, S., Lozanski, M., Nsiah, C., Wells, J., Tractenberg, R. E., Tractenberg, R. E., Chu, L. W., Yik, P. Y., Mok, W., Chung, C. P., Gauthier, S., Douillet, P., Doody, R., Fox, N. C., Orgogozo, J. M., Ingenbleek, Y., Bienvenu, J., Molloy, D. W., Standish, T., Cowan, D., Almeida, E., Diloreto, P., Woolmore-Goodwin, S., Clarke, J., Berardi, P., Smith, M., Purcell, T., Woolmore-Goodwin, S., Gutmanis, I., Borrie, M., Robert, P. H., Reynish, E., Cantet, C., Erder, M. H., Fillit, H., Hofbauer, R. K., Setyawan, J., Tourkodimitris, S., Fridman, M., Lyketsos, C., Unzeta, M., Valente, T., Hidalgo, J., Ramirez, B., Anglés, N., Morelló, J. R., Reguant, J., Boada, M., Claassen, J. A., Van Beek, A. H., Olde Rikkert, M. G., Roca, I., Cuberas, G., Castell, J., Buendia, M., Pla, R., Núñez, L., Ferrer, I., Latger, C., Tramoni, E., Elkhoury, C., Aubert-Khalfa, S., Ceccaldi, M., Schneeberger, A., Mandler, M., Otava, O., Mattner, F., Schmidt, W., Gatignol, P., David, C., Guitton, C., Plaza, M., Szaniszlo, P., German, P., Hajas, G., Kruzel, M., Boldogh, I., Wesnes, K., Satek, S., Turk, P., Satek, S., Vinay, M., Wetten, S., Li, H., Galwey, N., Gibson, R. A., Irizarry, M. C., Nourhashémi, F., Gillette-Guyonnet, S., Andrieu, S., Rolland, Y., Ousset, P. J., Verwey, N. A., Blennow, K., Clark, C., Cole, G. M., De Deyn, P. P., Galasko, D., Hampel, H., Hartmann, T., Kapaki, E., Lannfelt, L., Mehta, P. D., Parnetti, L., Petzold, A., Pirttila, T., Saleh, L., Skinningsrud, A., Swieten, J. C. V., Verbeek, M. M., Wiltfang, J., Younkin, S., Blankenstein, M. A., Ishihara-Paul, L., Viswanathan, A., Allen, J. K., Hyman, B. T., Betensky, R., Weil, J., The Alzheimer’s Disease Neuroimaging Initiative, The MAPT Study Investigators, The Xaliproden Ad Study Team, and the PLASA Group
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- 2008
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16. Acute pediatric hyperammonemia: current diagnosis and management strategies
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Savy N, Brossier D, Brunel-Guitton C, Ducharme-Crevier L, Du Pont-Thibodeau G, and Jouvet P
- Subjects
Critical Care ,hyperammonemia ,sodium phenylacetate ,hemodialysis ,sodium benzoate ,RC799-869 ,Diseases of the digestive system. Gastroenterology ,Pediatrics - Abstract
Nadia Savy,1 David Brossier,2 Catherine Brunel-Guitton,1 Laurence Ducharme-Crevier,1 Geneviève Du Pont-Thibodeau,1 Philippe Jouvet1 1Department of Pediatrics, CHU Sainte-Justine, University of Montreal, Montreal, QC, Canada; 2Department of Pediatrics, Pediatric Intensive Care Unit, CHU Caen, Caen, France Abstract: Acute hyperammonemia may induce a neurologic impairment leading to an acute life-threatening condition. Coma duration, ammonia peak level, and hyperammonemia duration are the main risk factors of hyperammonemia-related neurologic deficits and death. In children, hyperammonemia is mainly caused by severe liver failure and inborn errors of metabolism. In an acute setting, obtaining reliable plasma ammonia levels can be challenging because of the preanalytical difficulties that need to be addressed carefully. The management of hyperammonemia includes 1) identification of precipitating factors and cerebral edema presence, 2) a decrease in ammonia production by reducing protein intake and reversing catabolism, and 3) ammonia removal with pharmacologic treatment and, in the most severe cases, with extracorporeal therapies. In case of severe coma, transcranial Doppler ultrasound could be the method of choice to noninvasively monitor cerebral blood flow and titrate therapies. Keywords: pediatrics, critical care, hyperammonemia, sodium phenylacetate, sodium benzoate, hemodialysis
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- 2018
17. Safety culture in intensive care in france: is there a link with morbi-mortality conferences?
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Bretonnière, C and Guitton, C
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- 2015
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18. Aspects cliniques et prise en charge thérapeutique des méningites tuberculeuses: Analyse rétrospective de 15 cas observés de 1994 à 2005
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Bémer, P., Boutoille, D., Lepelletier, D., Chamoux, C., Guitton, C., and Drugeon, H.
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- 2006
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19. Incidence of Hemophiliac Arthropathy in Moderate and Mild Hemophilia Patients: A Retrospective Study from Paris-Bicêtre Hospital: PO-WE-162
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GUITTON, C., OIRON, R. D, TAMMAM, S., RAFOWICZ, A., DREYFUS, M., BADER-MEUNIER, B., LEZEAU, P., MARIE, P., PARIENTE, D., and LAMBERT, T.
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- 2012
20. First-trimester nuchal abnormalities secondary to dehydrated hereditary stomatocytosis
- Author
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Ami, O., Picone, O., Garçon, L., Castel, C., Guitton, C., Delaunay, J., Frydman, R., and Senat, M. V.
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- 2009
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21. Sensitivity of ID- and MP-NAT Systems Relative to P24/anti-HIV Elisa and Anti-HIV Chlia in Detecting Early HIV Infection: *SP256
- Author
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Assal, A, Barlet, V, Deschazeaux, M, Dupont, I, Gallian, P, Guitton, C, and Morel, P
- Published
- 2007
22. HEAD TO HEAD COMPARISON OF TWO NEW AUTOMATED NAT SYSTEMS CHIRON PROCLEIX TIGRIS SYSTEM VS ROCHE COBAS S 201: P-108
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Assal, A., Barlet, V., Cornillot, C., Deschazeaux, M., Dupont, I., Gallian, P., Guitton, C., Morel, P., and Andreu, G.
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- 2006
23. Infantile pyknocytosis: a cause of haemolytic anaemia of the newborn
- Author
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Eyssette-Guerreau, Stéphanie, Bader-Meunier, Brigitte, Garcon, Loïc, Guitton, C., and Cynober, Thérèse
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- 2006
24. Coombsʼ negative haemolytic anaemia as a first manifestation of autoimmune lymphoproliferative disease
- Author
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Guitton, C., Le Deist, F., and Bader-Meunier, B.
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- 2005
25. Subfamilies of histone H3 and H4 genes are located on most, possibly all of the chromosomes in maize
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Chaubet, N., Philipps, G., Gigot, C., Guitton, C., Bouvet, N., Freyssinet, G., Schneerman, M., and Weber, D. E.
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- 1992
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26. Identification of an RFLP marker tightly linked to theHt1 gene in maize
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Bentolila, S., Guitton, C., Bouvet, N., Sailland, A., Nykaza, S., and Freyssinet, G.
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- 1991
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27. Fatal herpetic hepatitis in adult following short corticotherapy: a case report
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Seksik, P., Gozlan, J., Guitton, C., Galula, G., Maury, E., and Offenstadt, G.
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- 1999
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28. Blood donors infected with the hepatitis B virus but persistently lacking antibodies to the hepatitis B core antigen
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Laperche, S., Guitton, C., Smilovici, W., and Courouce, A. M.
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- 2001
29. Enteral versus parenteral early nutrition in ventilated adults with shock: a randomised, controlled, multicentre, open-label, parallel-group study (NUTRIREA-2)
- Author
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Reignier, J., Boisrame-Helms, J., Brisard, L., Lascarrou, J. B., Ait Hssain, A., Anguel, N., Argaud, Laurent, Asehnoune, K., Asfar, P., Bellec, F., Botoc, V., Bretagnol, A., Bui, H. N., Canet, E., Da Silva, D., Darmon, M., Das, V., Devaquet, J., Djibre, M., Ganster, F., Garrouste-Orgeas, M., Gaudry, S., Gontier, O., Guerin, C., Guidet, B., Guitton, C., Herbrecht, J. E., Lacherade, J. C., Letocart, P., Martino, F., Maxime, V., Mercier, E., Mira, J. P., Nseir, S., Piton, G., Quenot, J. P., Richecoeur, J., Rigaud, J. P., Robert, R., Rolin, N., Schwebel, C., Sirodot, M., Tinturier, F., Thevenin, D., Giraudeau, B., Le Gouge, A., Investigators, Nutrirea- Trial, Intensive, Care, Sepsis, group, Cardiovasculaire, métabolisme, diabétologie et nutrition (CarMeN), Institut National de la Recherche Agronomique (INRA)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Hospices Civils de Lyon (HCL), and Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Hospices Civils de Lyon (HCL)-Institut National de la Santé et de la Recherche Médicale (INSERM)
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Male ,Adult ,Enteral Nutrition ,Shock/complications/mortality/*therapy ,Time Factors ,Respiration ,[SDV]Life Sciences [q-bio] ,Vasoconstrictor Agents/therapeutic use ,Length of Stay ,Middle Aged ,Critical Care ,Treatment Outcome ,Artificial ,Humans ,Female ,Hospital Mortality ,Parenteral Nutrition ,Aged - Abstract
BACKGROUND: Whether the route of early feeding affects outcomes of patients with severe critical illnesses is controversial. We hypothesised that outcomes were better with early first-line enteral nutrition than with early first-line parenteral nutrition. METHODS: In this randomised, controlled, multicentre, open-label, parallel-group study (NUTRIREA-2 trial) done at 44 French intensive-care units (ICUs), adults (18 years or older) receiving invasive mechanical ventilation and vasopressor support for shock were randomly assigned (1:1) to either parenteral nutrition or enteral nutrition, both targeting normocaloric goals (20-25 kcal/kg per day), within 24 h after intubation. Randomisation was stratified by centre using permutation blocks of variable sizes. Given that route of nutrition cannot be masked, blinding of the physicians and nurses was not feasible. Patients receiving parenteral nutrition could be switched to enteral nutrition after at least 72 h in the event of shock resolution (no vasopressor support for 24 consecutive hours and arterial lactate \textless2 mmol/L). The primary endpoint was mortality on day 28 after randomisation in the intention-to-treat-population. This study is registered with ClinicalTrials.gov, number NCT01802099. FINDINGS: After the second interim analysis, the independent Data Safety and Monitoring Board deemed that completing patient enrolment was unlikely to significantly change the results of the trial and recommended stopping patient recruitment. Between March 22, 2013, and June 30, 2015, 2410 patients were enrolled and randomly assigned; 1202 to the enteral group and 1208 to the parenteral group. By day 28, 443 (37%) of 1202 patients in the enteral group and 422 (35%) of 1208 patients in the parenteral group had died (absolute difference estimate 2.0%; [95% CI -1.9 to 5.8]; p=0.33). Cumulative incidence of patients with ICU-acquired infections did not differ between the enteral group (173 [14%]) and the parenteral group (194 [16%]; hazard ratio [HR] 0.89 [95% CI 0.72-1.09]; p=0.25). Compared with the parenteral group, the enteral group had higher cumulative incidences of patients with vomiting (406 [34%] vs 246 [20%]; HR 1.89 [1.62-2.20]; p\textless0.0001), diarrhoea (432 [36%] vs 393 [33%]; 1.20 [1.05-1.37]; p=0.009), bowel ischaemia (19 [2%] vs five [\textless1%]; 3.84 [1.43-10.3]; p=0.007), and acute colonic pseudo-obstruction (11 [1%] vs three [\textless1%]; 3.7 [1.03-13.2; p=0.04). INTERPRETATION: In critically ill adults with shock, early isocaloric enteral nutrition did not reduce mortality or the risk of secondary infections but was associated with a greater risk of digestive complications compared with early isocaloric parenteral nutrition. FUNDING: La Roche-sur-Yon Departmental Hospital and French Ministry of Health.
- Published
- 2018
30. Syndrome de détresse respiratoire aiguë d’origine professionnelle : que se passe-t-il dans le silo ?
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Courtais, A., primary, Paris, A., additional, Julien, A., additional, Chudeau, N., additional, Goupil, F., additional, and Guitton, C., additional
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- 2019
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31. Dyscalcémie aux urgences
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Guitton, C., Renard, B., Gabillet, L., and Villers, D.
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- 2002
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32. HEREDITARY XEROCYTOSIS: CLINICAL AND BIOLOGICAL PRESENTATION AT DIAGNOSIS IN A RETROSPECTIVE SERIES OF 103 PATIENTS
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Picard, V., Guitton, C., Lahary, A., Martinez, P. Aguilar, Ruivard, M., Rose, C., Perrin, J., Barro, C., Lifermann, F., Jaureguiberry, J. -P., Deconinck, E., Beneteau, C., Lefebvre, T., Toutain, F., Le Coz, M. -F., Berger, C., Proulle, V., Beris, P., Godeau, B., Very, C., Garcon, Loic, Centre hospitalier universitaire de Nantes (CHU Nantes), Hôpital Charles Nicolle [Rouen], CHU Rouen, Normandie Université (NU)-Normandie Université (NU), CHU Clermont-Ferrand, SIGMA Clermont, Université Clermont Auvergne [2017-2020] (UCA [2017-2020]), Centre National de la Recherche Scientifique (CNRS), Université catholique de Lille (UCL), Oncologie médicale [Hôpital Saint Vincent de Paul, Lille], Hôpital Saint-Vincent de Paul, Service de Gynécologie et Obstétrique [Marseille], Hôpital de la Conception [CHU - APHM] (LA CONCEPTION), Laboratoire d'Hématologie, CHU Grenoble, Centre Hospitalier de Dax, Service d'Hématologie [CHRU Besançon], Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon), Laboratoire d'Ecologie Alpine (LECA ), Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019]), CHU Pontchaillou [Rennes], CEA-Direction des Energies (ex-Direction de l'Energie Nucléaire) (CEA-DES (ex-DEN)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Université de Picardie Jules Verne (UPJV), CHU Amiens-Picardie, AP-HP Hôpital Bicêtre (Le Kremlin-Bicêtre), and DESSAIVRE, Louise
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[SDV] Life Sciences [q-bio] ,[SDV]Life Sciences [q-bio] ,parasitic diseases ,education ,social sciences ,health care economics and organizations ,geographic locations - Abstract
22nd Congress of the European-Hematology-Association, Madrid, SPAIN, JUN 22-25, 2017; International audience
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- 2017
33. PHYSIOPATHOLOGY OF HEREDITARY XEROCYTOSIS: PIEZO1 GAIN OF FUNCTION MUTATIONS IMPACT HEMOGLOBIN OXYGEN AFFINITY
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Kiger, L., Guitton, C., Ghazal, K., Feneant-Thibault, M., Bendelac, L., Galacteros, F., Proulle, V., Garcon, Loic, Picard, V., DESSAIVRE, Louise, Hôpital Henri Mondor, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Henri Mondor-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Centre hospitalier universitaire de Nantes (CHU Nantes), Centre de Recherche Saint-Antoine (CRSA), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU), Université Paris-Est Créteil Val-de-Marne - Faculté de médecine (UPEC Médecine), Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Université de Picardie Jules Verne (UPJV), CHU Amiens-Picardie, and AP-HP Hôpital Bicêtre (Le Kremlin-Bicêtre)
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[SDV] Life Sciences [q-bio] ,[SDV]Life Sciences [q-bio] ,parasitic diseases ,education ,social sciences ,health care economics and organizations ,geographic locations - Abstract
22nd Congress of the European-Hematology-Association, Madrid, SPAIN, JUN 22-25, 2017; International audience
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- 2017
34. Erratum to “Intubation and extubation of the ICU patient” [Anaesth. Crit. Care Pain Med. 36 (5) (2017) 327–341]
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Quintard, H., primary, l’Her, E., additional, Pottecher, J., additional, Adnet, F., additional, Constantin, J.-M., additional, De Jong, A., additional, Diemunsch, P., additional, Fesseau, R., additional, Freynet, A., additional, Girault, C., additional, Guitton, C., additional, Hamonic, Y., additional, Maury, E., additional, Mekontso-Dessap, A., additional, Michel, F., additional, Nolent, P., additional, Perbet, S., additional, Prat, G., additional, Roquilly, A., additional, Tazarourte, K., additional, Terzi, N., additional, Thille, A.W., additional, Alves, M., additional, Gayat, E., additional, and Donetti, L., additional
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- 2018
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35. Prélèvements multiorganes de type Maastricht III en médecine intensive–réanimation. Organisation et retour d’expérience paramédicale dans un service pilote
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Rouzeau, C., primary, Lecomte, E., additional, Cailleton, A., additional, Cornuault, M., additional, Boulinguiez, C., additional, Labourot, P., additional, Reignier, J., additional, and Guitton, C., additional
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- 2018
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36. Acute reversible neurological and renal failure following acyclovir treatment
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Guitton, C., Maury, E., Mohand, D., Feldman, F., Lokiek, F., Guidet, B., and Offenstadt, G.
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- 1999
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37. Acute pulmonary edema following amphetamine ingestion
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Maury, E., Darondel, J. M., Buisinne, A., Guitton, C., and Offenstadt, G.
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- 1999
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38. UNSMAKING PRIMARY IMMUNE DEFICIENCIES IN EARLY-ONSET EVANS SYNDROME ă USING IMMUNOPHENOTYPING AND NGS: TOWARDS A CLINICAL AND GENETIC ă CLASSIFICATION
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Rieux-Laucat, F., Aladjidi, N., Picard, C., Fernandes, H., Bertrand, Yves, Barlogis, V., Pasquet, M., Levy, E., Mazingue, F., Guitton, C., Magerus, A., Leblanc, T., Leverger, G., Fischer, A., Developpement Normal et Pathologique du Système Immunitaire, Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Centre d'Immunologie de Marseille - Luminy (CIML), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Aix Marseille Université (AMU), Etablissement Français du Sang - Alpes-Méditerranée (EFS - Alpes-Méditerranée), Etablissement Français du Sang, Anthropologie bio-culturelle, Droit, Ethique et Santé (ADES), Aix Marseille Université (AMU)-EFS ALPES MEDITERRANEE-Centre National de la Recherche Scientifique (CNRS), Santé Publique et maladies Chroniques : Qualité de vie Concepts, Usages et Limites, Déterminants (SPMC), Aix Marseille Université (AMU)-Assistance Publique - Hôpitaux de Marseille (APHM), Centre Hospitalier Universitaire de La Réunion (CHU La Réunion), Jet Propulsion Laboratory (JPL), NASA-California Institute of Technology (CALTECH), Service d'hématologie-immunologie-oncologie pédiatrique [CHU Trousseau], Université Pierre et Marie Curie - Paris 6 (UPMC)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-CHU Trousseau [APHP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Laboratoire de Physique des Lasers (LPL), Université Paris 13 (UP13)-Centre National de la Recherche Scientifique (CNRS), Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), CHU Trousseau [APHP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Sorbonne Université (SU), Université Paris Descartes - Paris 5 ( UPD5 ) -Institut National de la Santé et de la Recherche Médicale ( INSERM ) -Centre National de la Recherche Scientifique ( CNRS ), Centre d'Immunologie de Marseille - Luminy ( CIML ), Aix Marseille Université ( AMU ) -Institut National de la Santé et de la Recherche Médicale ( INSERM ) -Centre National de la Recherche Scientifique ( CNRS ), Etablissement Français du Sang - Alpes-Méditerranée ( EFS - Alpes-Méditerranée ), Anthropologie bio-culturelle, Droit, Ethique et Santé ( ADES ), Aix Marseille Université ( AMU ) -EFS ALPES MEDITERRANEE-Centre National de la Recherche Scientifique ( CNRS ), Santé Publique et maladies Chroniques : Qualité de vie Concepts, Usages et Limites, Déterminants ( SPMC ), Aix Marseille Université ( AMU ) -Assistance Publique - Hôpitaux de Marseille ( APHM ), Centre Hospitalier Universitaire de La Réunion ( CHU La Réunion ), Jet Propulsion Laboratory ( JPL ), NASA-California Institute of Technology ( CALTECH ), Service d'hématologie-immunologie-oncologie pédiatrique, Université Pierre et Marie Curie - Paris 6 ( UPMC ) -Assistance publique - Hôpitaux de Paris (AP-HP)-CHU Trousseau [APHP], Laboratoire de Physique des Lasers ( LPL ), Université Paris 13 ( UP13 ) -Université Sorbonne Paris Cité ( USPC ) -Institut Galilée-Centre National de la Recherche Scientifique ( CNRS ), Université Pierre et Marie Curie - Paris 6 (UPMC)-Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-CHU Trousseau [APHP], and Université Sorbonne Paris Cité (USPC)-Institut Galilée-Université Paris 13 (UP13)-Centre National de la Recherche Scientifique (CNRS)
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[ SHS.PSY ] Humanities and Social Sciences/Psychology ,[ SDV.MHEP.PSM ] Life Sciences [q-bio]/Human health and pathology/Psychiatrics and mental health ,[SDV.MHEP.PSM]Life Sciences [q-bio]/Human health and pathology/Psychiatrics and mental health ,[ SHS.ECO ] Humanities and Social Sciences/Economies and finances ,[SHS.PSY]Humanities and Social Sciences/Psychology ,[ SDV.SPEE ] Life Sciences [q-bio]/Santé publique et épidémiologie ,[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie ,[SHS.ECO]Humanities and Social Sciences/Economics and Finance ,Quality - Abstract
21st Congress of the European-Hematology-Association, Copenhagen, ă DENMARK, JUN 09-12, 2016; International audience; no abstract
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- 2016
39. Rapid rEcognition of COrticosteRoiD resistant or sensitive Sepsis (RECORDS): study protocol for a multicentre, placebo-controlled, biomarker-guided, adaptive Bayesian design basket trial
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Shidasp Siami, Charlène Le Moal, Thomas DAIX, Sylvie Chevret, Yonatan Perez, Constance Vuillard, Damien Roux, Jonathan Messika, Stephan Ehrmann, Jean-Pierre Quenot, Dalila Benzekri, Gwenhaël Colin, Thierry Boulain, Julie Mankikian, Laura Federici, Jean Reignier, Jean-Paul Mira, Marie-Ange Azais, Djillali Annane, Jean-Claude Lacherade, Grégoire Muller, Christine Lebert, Nicholas Heming, Arthur Bailly, Emmanuelle Mercier, Jean-Baptiste Lascarrou, Julio Badie, Louis-Marie Dumont, Gaetan Plantefeve, Francis Schneider, Patrice Tirot, Isabelle Vinatier, Mickael Landais, Michel Djibré, Bruno Francois, Alexandra Monnier, Francois Barbier, Ferhat Meziani, Hamid Merdji, Pascal Andreu, Julie Helms, Laetitia Bodet-Contentin, Nicolas Pichon, Noémie Zucman, Mehran Monchi, Xavier Monnet, Marie Labruyère, Denis Garot, Hassène Rahmani, Jérôme Fleuriet, Pierre-Louis Declerq, Adrien Robine, Fabrice Uhel, Charles Cerf, Gilles Troché, Alexandrou Antigoni, Annane Djillali, Arlt Birte, Badie Julio, Benghanem Sarah, Berdaguer Ferrari Fernando, Cerf Charles, Chelly Dagdia Zaineb, Chevret Sylvie, Colin Gwenhaël, Daniel Christel, Declercq Pierre-Louis, Delbove Agathe, Devillier Philippe, Fleuriet Jérome, François Bruno, Garchon Henri-Jean, Godot Véronique, Grassin-Delyle Stanislas, Grisolia Mathieu, Guitton Christophe, Helms Julie, Heming Nicholas, Herzog Marielle, Kamel Toufik, Kedad Zoubida, Lassalle Philippe, Lhermite Guillaume, Megarbane Bruno, Mekontso Dessap Armand, Mercier Emmanuelle, Meziani Ferhat, Mira Jean-Paul, Monchi Mehran, Monnet Xavier, Muller Grégoire, Quenot Jean-Pierre, Reignier Jean, Robine Adrien, Rottman Martin, Roux Anne-Laure, Schneider Francis, Siami Shidasp, Tissieres Pierre, Troché Gilles, Uhel Fabrice, Zeitouni Karine, Plantefève Gaëtan, Walid Darwiche, Antoine Guillon, Youenn Jouan, Annick Legras, Marlene Morisseau, Emmanuelle Rouve, Charlotte Salmon-Gandonniere, Raphael Clere-Jehl, Laure Stiel, Antoine Studer, Jean-Baptiste Roudaut, Marine Jacquier, Sophie Jacquier, Armelle Mathonnet, Mai-Anh Nai, Isabelle Runge, Sophie Tollec, Marc Amouretti, Pierre Moine, Paris Meng, Rania Bounab, Muriel-Sarah Fartoukh, Alexandre Elabbadi, Konstantinos Bachoumas, Remi Bernardon, Gauthier Blonz, Luc Desmedt, Brian Emonet, Maud Fiancette, Matthieu Henry, Julien Lorber, Laurent Martin-Lefevre, Caroline Pouplet, Aihem Yehia, Sarah Benghanem, Julien Charpentier, Clara Vigneron, Anne-Laure Fedou, Claire Mancia, Emmanuelle Begot, Philippe Vignon, Antoine Galy, Celine Gonzalez, Marine Goudelin, Bruno Evrard, Arnaud Desachy, Julien Vaidie, Guillaume Gilbert, Cedric Darreau, Benoit Derrien, Marjorie Saint-Martin, Nicolas Chudeau, Jean Christophe Callahan, Dominique Vivier, Pierre-Yves Olivier, Remy Marnai, Nicolas Sedillot, Xavier Tchenio, Yves Poncelin, Remi Bruyere, Grimaldi Lamiae, and Derridj Nawal
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Medicine - Abstract
Introduction Corticosteroids affect variably survival in sepsis trials, suggesting heterogeneity in patients’ response to corticosteroids. The RECORDS (Rapid rEcognition of COrticosteRoiD resistant or sensitive Sepsis) trial aimed at defining endotypes associated with adults with sepsis responsiveness to corticosteroids.Methods and analysis RECORDS, a multicentre, placebo-controlled, biomarker-guided, adaptive Bayesian design basket trial, will randomly assign to a biomarker stratum 1800 adults with community-acquired pneumonia, vasopressor-dependent sepsis, septic shock or acute respiratory distress syndrome. In each stratum, patients will be randomly assigned to receive a 7-day course of hydrocortisone and fludrocortisone or their placebos. Patients with COVID-19 will be treated with a 10-day standard course of dexamethasone and randomised to fludrocortisone or its placebo. Primary outcome will be 90-day death or persistent organ dysfunction. Large simulation study will be performed across a range of plausible scenarios to foresee power to detect a 5%–10% absolute difference with corticosteroids. We will assess subset-by-treatment interaction by estimating in a Bayesian framework two quantities: (1) measure of influence, relying on the value of the estimation of corticosteroids’ effect in each subset, and (2) measure of interaction.Ethics and dissemination The protocol was approved by the Ethics Committee (Comité de Protection des Personnes, Dijon, France), on 6 April 2020. Trial results will be disseminated at scientific conferences and results will be published in peer-reviewed journals.Trial registration number ClinicalTrials.gov Registry (NCT04280497).
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- 2023
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40. French Intensive Care Society, International congress - Réanimation 2016
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Jaillette, E, Girault, C, Brunin, G, Zerimech, F, Chiche, A, Broucqsault Dedrie, C, Fayolle, C, Minacori, F, Alves, I, Barrailler, S, Robriquet, L, Delaporte, E, Thellier, D, Delcourte, C, Duhamel, A, Nseir, S, Valette, X, Desmeulles, I, Savary, B, Masson, R, Seguin, A, Daubin, C, Sauneuf, B, Verrier, P, Pottier, V, Orabona, M, Samba, D, Viquesnel, G, Lermuzeaux, M, Hazera, P, Hanouz, J, Parienti, J, Du Cheyron, D, Demoule, A, Clavel, M, Rolland Debord, C, Perbet, S, Terzi, N, Kouatchet, A, Wallet, F, Roze, H, Vargas, F, Guérin, C, Dellamonica, J, Jaber, S, Similowski, T, Quenot, J, Binquet, C, Vinsonneau, C, Barbar, S, Vinault, S, Deckert, V, Lemaire, S, Hssain, A, Bruyère, R, Souweine, B, Lagrost, L, Adrie, C, Jung, B, Daurat, A, De Jong, A, Chanques, G, Mahul, M, Monnin, M, Molinari, N, Lheureux, O, Trepo, E, Hites, M, Cotton, F, Wolff, F, Surin, R, Créteur, J, Vincent, J, Gustot, T, Jacobs, F, Taccone, F, Neuville, M, Timsit, J, El Helali, N, Le Monnier, A, Magalhaes, E, Radjou, A, Smonig, R, Soubirou, J, Voiriot, G, Sonneville, R, Bouadma, L, Mourvillier, B, Gélisse, E, Brasseur, A, Roisin, S, De Backer, D, Van Ruychevelt, V, Carlier, E, Piagnerelli, M, Vanhaeverbeek, M, Danguy, C, Biston, P, Au, S, Begot, E, Dalmay, F, Repessé, X, Prat, G, Bouferrache, K, Slama, M, Vieillard Baron, A, Monnet, X, Marik, P, Teboul, J, Jozwiak, M, Richard, C, Chauvet, J, El Dash, S, Delastre, O, Bouffandeau, B, Jusserand, D, Michot, J, Bauer, F, Brazier, F, Mercado, P, Kontar, L, Titeca, D, De Cagny, B, Bacari Risal, G, Riviere, A, Maizel, J, Guillot, C, Le Reun, C, Lampin, M, Sadik, A, Botte, A, Leteurtre, S, Collins, A, Kempeneers, C, Cajgfinger, N, Ohlmann, C, Pouyau, R, Subtil, F, Baudin, F, Massenavette, B, Javouhey, E, Milesi, C, Essouri, S, Liet, J, Afanetti, M, Durand, S, Durand, P, Roze, J, Dupont, D, Cambonie, G, Soyer, B, Rusca, M, Lukaszewicz, A, Crassard, I, Guichard, J, Bresson, D, de la Garanderie, D, Cantier, M, Sabben, C, Louedec, L, Delbosc, S, Journé, C, Ou, P, Klein, I, Chau, F, Lefort, A, Desilles, J, Michel, J, Mazighi, M, Salem, O, Demeret, S, Bolgert, F, Sharshar, T, Grabli, D, Arib, S, Crippa, I, Soummer, A, Engrand, N, Guedin, P, Aldea, S, Cerf, C, Desailly, V, Pasquier, P, Brun, P, Roux, D, Latournerie, G, Kasprzyk, L, Grosjean, V, Latreche, A, Habert, P, Huot, S, Jobin, T, Tesnière, A, Dreyfuss, D, Ricard, J, Mignon, A, Gaudry, S, Laithier, F, Kimmoun, A, Chouihed, T, Albizzati, S, Camenzind, E, Vanhuyse, F, Levy, B, Cour, M, Venet, F, Hernu, R, Demaret, J, Monneret, G, Argaud, L, Dumas, F, Lamhaut, L, Rosencher, J, Pène, F, Varenne, O, Carli, P, Jouven, X, Spaulding, C, Cariou, A, Geri, G, Bonnetain, F, Marijon, E, Empana, J, Mirouse, A, Resche Rigon, M, Mayaux, J, Rabbat, A, Meert, A, Benoit, D, Bruneel, F, Azoulay, E, Dupuis, C, Schwebel, C, Ruckly, S, Goldgran Toledano, D, Marcotte, G, Lafarge, A, Pichereau, C, Theodose, I, Scotto, M, Kemlin, D, Ghrenassia, E, Schlemmer, B, Vimpere, D, Galicier, L, Contou, D, Guérot, E, Grimaldi, D, Ricome, S, Maury, E, Plantefève, G, Dessap, A, Brun Buisson, C, de Prost, N, Dubé, B, Delemazure, J, Dres, M, Rousseau, L, Drouot, X, Diaz, V, Rebollar, Y, Frat, J, Thille, A, Aissa, D, Coquet, P, Ruiz, J, Ferre, F, Hoarau, L, Riu Poulenc, B, Bataille, B, Silva, S, Baudel, J, Bigé, N, Tahiri, J, Dubée, V, Guidet, B, Ait Oufella, H, Jinglun, L, Shen, F, Bailly, S, Leroy, O, Montravers, P, Constantin, J, Dupont, H, Guillemot, D, Lortholary, O, Perrigault, P, Gangneux, J, Razazi, K, Mekontso Dessap, A, Jansen, C, Lecronier, M, Sandrine, V, Mira, J, Blein, S, Marin, N, Rousseau, C, Charpentier, J, Pachot, A, Hraiech, S, Bordes, J, De, L, Mège, J, Forel, J, Guervilly, C, Adda, M, Raoult, D, Papazian, L, Kentish Barnes, N, Cohen Solal, Z, Souppart, V, Kerhuel, L, Haubertin, C, Exbrayat, I, Rozières, E, Argain, A, Suc, A, Vignes, M, Cougot, P, Fourcade, O, Brunel, E, Messika, J, Tubach, F, Dubief, E, Pasquet, B, Guillo, S, Pierron, C, Grimaud, M, Farnoux, C, Maillard, A, Decavèle, M, Prodanovic, H, Idbaih, A, Alentorn, A, Delattre, J, De Montmollin, E, Brule, N, Conrad, M, Dailler, F, Navellou, J, Alves, M, Tonnelier, J, Picard, G, Rogemond, V, Honnorat, J, Marzorati, C, Lebert, C, Perez, P, Citerio, G, Legriel, S, Tripon, S, Mallet, M, Rudler, M, Imbert Bismut, F, Thabut, D, Canet, E, Faguer, S, Moreau, A, Barbier, F, Merceron, S, Guitton, C, Labadie, F, Lemiale, V, Faucher, E, Klouche, K, Chevret, S, Ragot, S, Coudroy, R, Boulain, T, Jamet, A, Mercat, A, Brochard, L, Roux, A, Franchineau, G, Brechot, N, Lebreton, G, Hekimian, G, Nieszkowska, A, Leprince, P, Trouillet, J, Combes, A, Schmidt, M, Barrot, L, Piton, G, Bailey, M, Panwar, R, Belin, N, Belon, F, Patry, C, Grandperrin, M, Chaignat, C, Labro, G, Vivet, B, Capellier, G, Daix, T, Guérin, E, Tavernier, E, Mercier, E, Gissot, V, Vallejo, C, François, B, Ravry, C, Pichon, N, Chapellas, C, Fedou, A, Galy, A, Ploy, M, Barraud, O, Vignon, P, Thooft, A, Conotte, R, Colet, J, Le Dorze, M, Tarazona, V, Brumpt, C, Moins Teisserenc, H, Uhel, F, Azzaoui, I, Gregoire, M, Pangault, C, Dulong, J, Cynober, L, Roussel, M, Le Tulzo, Y, Tarte, K, Demiselle, J, Auchabie, J, Dequin, P, Chudeau, N, Fourrier, F, Grange, S, Piquilloud, L, Lautrette, A, Boyer, S, Letheulle, J, Lerolle, N, Truche, A, Clec'H, C, Zaoui, P, Laurent, V, Toledano, D, Ragey, S, Gros, A, Dumenil, A, Jamali, S, Darmon, M, Chouraqui, M, Dewitte, A, Chastel, B, Carles, P, Fleureau, C, Joannes Boyau, O, Ouattara, A, Joseph, A, Garrouste Orgeas, M, Max, A, Lerin, T, Grégoire, C, Kloeckner, M, Bruel, C, Brochon, S, Philippart, F, Pichot, E, Simons, C, Flint, A, Aubron, C, Bellomo, R, Pilcher, D, Cheng, A, Hegarty, C, Martinelli, A, Howden, B, Reade, M, Mcquilten, Z, Bretonnière, C, Villers, D, Soares, M, Gonzalez, F, Vincent, F, Fauché, C, Gay, S, Skowron, O, Levrat, A, Dorez, D, Foucrier, A, Pease, S, Gauss, T, Paugam, C, Gorham, J, Ameye, L, Paesmans, M, Berghmans, T, Sculier, J, Deras, P, Martinez, O, Latry, P, Capdevila, X, Charbit, J, Jaubert, J, Etiennar, C, Ginoux, L, Sebbah, J, Haouache, H, Dhonneur, G, Cheikh, C, Moussaid, I, Ghazaoui, O, Belkadi, K, El Youssoufi, S, Salmi, S, Pajot, L, Zuber, B, Bedos, J, Dupont, B, Eugène, A, Galateau Sallé, F, Michard, B, Lebas, B, Boivin, A, Guillot, M, Harlay, M, Janssen Langenstein, R, Schenck, M, Ellero, B, Woehl Jaegle, M, Besch, C, Castelain, V, Bachellier, P, Schneider, F, Camus, C, Saliba, F, Goubaux, B, Bonadona, A, Lavayssiere, L, Quinart, A, Barbot, O, Dharancy, S, Delafosse, B, Barraud, H, Galbois, A, Veber, B, Cayot, S, Souche, B, Locher, C, Roux, O, Figorilli, F, Putignano, A, Houssel, P, Francoz, C, Weiss, E, Agarwal, B, Jalan, R, Durand, F, Ghezala, H, Daoudi, R, Kaddour, M, Ghadhoune, H, Rachedi, E, Guissouma, J, Ben Slimene, A, Azzeza, W, Brahmi, H, Elghord, H, Kada, A, Chikh, R, Slimani, R, A. 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Deboscker, S, Harley, M, Lavigne, T, Brunet, J, Canoville, B, Lellouche, F, L'Her, E, Bouchard, P, Delorme, M, Elfaramawy, T, Gosselin, B, Guegan, S, Michotte, J, Staderini, E, Dugernier, J, Rusu, R, Liistro, G, Reychler, G, Simon, M, Essoukaki, E, Duprez, F, Contal, O, Trabelsi, B, Garsallah, H, Harira, K, Rafat, C, Mariotte, E, Le Jeune, C, Roy, P, Michallet, M, Zerbib, Y, Blot, F, Bornstain, C, Gelinotte, S, Rigaud, J, Tamion, F, Bouteloup, M, Nouira, H, Boisramé Helms, J, Degirmenci, S, Kummerlen, C, Delile, E, Thiébaut, P, Do Rego, J, Coquerel, D, Nevière, R, Ichou, L, Carbonell, N, Rautou, P, Nousbaum, J, Renou, C, Anty, R, Landraud, L, Lecron, J, Helary, M, Paillot, J, Pili Floury, S, Khedher, S, Maoui, A, Ezzamouri, A, Salem, M, Kerdjana, L, Dumitrescu, M, Mimoz, O, Debaene, B, Migeot, V, Dahyot Fizelier, C, Champigneulle, B, Zafrani, L, Lascarrou, J, Lissonde, F, Le Thuaut, A, Reignier, J, Platon, L, Lambert, J, Lagier, D, Brun, J, Sannini, A, Chow Chine, L, Bisbal, M, 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P, Boles, J, Herbrecht, J, Kaeuffer, C, Meyer, A, Arfi, K, Lesage, F, Séguret, S, Dupic, L, De Saint Blanquat, L, Baptiste, A, Georges, H, Delannoy, P, Devos, P, Albarracin, D, Ducousso Lacaze, A, Dufour, J, Cabasson, S, Veinstein, A, Chatellier, D, Robert, R, Ha, V, Lau, N, Mimoun, L, Forceville, X, Maamar, A, Chevalier, S, Botoc, V, Rouleau, S, Desachy, A, Calvat, S, Lafon, C, Cracco, C, Temime, J, Molmy, P, Gasan, G, Béranger, A, Chappuy, H, Bertrand, P, Beurton, A, Bodet Contentin, L, Danin, P, Dubois, E, Karaca, Y, Mora, P, Vodovar, D, Desbrosses, Y, Chauchet, A, Daguindau, E, Deconinck, E, Chermak, A, Baron, M, Calvet, L, Sapin, A, Pereira, B, Vettoretti, L, Lacroix, J, Clayton, L, Sabri, E, Bardiaux, L, Tiberghien, P, Hebert, P, Lengliné, E, Socié, G, Borcoman, E, Rusinova, K, Del Galy, A, Mercier, M, Hamel, J, Raveau, T, Moles, M, Clavert, A, Hunault Berger, M, Ifrah, N, Schmidt Tanguy, A, Carreira, S, Lavault, S, Pallanca, O, Morawiec, E, Arnulf, I, D'Humières, T, Carrié, C, Gisbert Mora, C, Bonnardel, E, Biais, M, Hilbert, G, Joannon, T, Marincamp, A, Chiche, J, Ferre, A, Lichtenstein, D, Meziere, G, Gonzalez, C, Hamzaoui, O, Geffriaud, T, Leleu, F, Boissier, F, Cuquemelle, E, Lim, P, Amara, R, Léger, J, Jacob, C, Bouferache, K, Ragot, C, Corradi, L, Maurice, L, Julliand, S, Deho, A, Le Bourgeois, F, Jacquot, A, Valla, F, Letois, F, Salvadori, A, Ottonello, G, Blanot, S, Montmayeur, J, Orliaguet, G, Tarmiz, K, Habas, F, Baleine, J, Lebouhellec, J, Combes, C, Chomton, M, Jouvet, P, Ranchin, B, Macher, M, Gaillot, T, Moine, M, Ageron, F, Jannel, C, Debillon, T, Wroblewski, I, Duprey, M, Jarlier, V, Luyt, C, Longval, T, Schnell, D, Padoin, C, Cohen, Y, Gaies, E, Triki, S, Klouz, A, Moussa, M, Desrumaux, F, May, F, Nguyen, J, Tiercelet, K, Fournier, J, Cherin, M, Kitzis, M, Misset, B, Mathien, C, Poidevin, A, Donatti, L, Mootien, J, Pinto, L, Egard, M, Bodur, G, Barberet, G, Ionescu, C, Ganster, F, Guiot, P, Kuteifan, K, Mpela, A, Chelly, J, Guérin, L, 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Nativel, B, Planesse, C, Diotel, N, Meilhac, O, Roy Gash, F, Lebard, C, Larbi, A, Gaudin, V, Bonnin, F, Sultan, O, Hoc, C, Mathieu, E, Lapergue, B, Bourdain, F, Caron, M, Parrot, A, Labbe, V, Hafiani, E, Quesnel, C, Genay, S, Décaudin, B, Ethgen, S, Odou, P, Lebuffe, G, Mcquilte, Z, Allaouchiche, B, Verdière, B, Nyunga, M, Banaias, N, Colling, D, Kauv, M, Blondeau, E, Auclin, E, Haw Berlemont, C, Taieb, J, Oudard, S, Morissette, G, Kechaou, W, Litalien, C, Merouani, A, Phan, V, Bouchard, J, Starck, J, Briand, N, Sachs, P, Angoulvant, F, Sommet, J, Holvoet, L, Benkerrou, M, Dreyfus, L, Bordet, F, Touzet, S, Denis, A, Le Coz, J, Chéron, G, Nabbout, R, Patteau, G, Heilbronner, C, Hubert, P, Oualha, M, Crulli, B, Toledano, B, Poirier, N, Vobecky, S, Khouadja, H, Vinet, M, Vinclair, C, Beloncle, F, Radermacher, P, Asfar, P, Coupez, E, Bohé, J, Shinotsuka, C, Caironi, P, Villois, P, Fontana, V, Creteur, J, Pourcine, F, Vong, L, Weyer, C, Akando, B, Abdallah, R, Wetzstein, M, Antier, N, Serroukh, Y, Boudjeltia, K, Joosten, A, Rousseau, A, Delabranche, X, Grunebaum, L, Mootien, Y, Gaci, R, Garric, J, Delbove, A, Darreau, C, Dargent, A, Soudry Faure, A, De Chambrun, M, Demondion, P, Blanchard, J, Chocron, S, Meneveau, N, Corsi, F, Meynieu, P, Repusseau, B, Germain, A, Baudry, G, Hierle, L, Besch, G, Thomas, G, Cassir, N, Dizier, S, Roch, A, Trebbia, G, Govindaradjou, K, Devaquet, J, Picard, C, Parquin, F, Leguen, M, Felten, M, Sage, E, Chapelier, A, Duruisseaux, M, Fleury, J, Antoine, M, Carette, M, Wislez, M, Givel, C, De Margerie Mellon, C, De Kerviler, E, Tandjaoui Lambiotte, Y, Freynet, O, Baux, E, Das, V, Talec, P, Anguel, N, Louis, G, Girerd, N, Tallon, P, Hadchouel Duvergé, A, Salvi, N, Cairet, P, Delacourt, C, Blandine, B, Beraud, L, Lamaziere, A, Lionnet, F, Lehingue, S, D'Journo, X, Jean Marie, F, Thibault, R, Makhlouf, A, Mulliez, A, Dadet, S, Kekstas, G, Preiser, J, Rotovnik, K, Rozalen, I, Kupczyk, K, Krznaric, Z, Cano, N, Pichard, C, Le Roux, B, Jotterand, 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Elkhawand, C, Vermeesh, F, Vermeesh, F., and CITERIO, GIUSEPPE
- Abstract
Determinants of outcome in critically ill patients with hematological malignancy and central neurological failure: data from the TRIAL OH study
- Published
- 2016
41. An N-terminal formyl methionine on COX 1 is required for the assembly of cytochrome c oxidase
- Author
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Hinttala, R., Sasarman, F., Nishimura, T., Antonicka, H., Brunel-Guitton, C., Schwartzentruber, J., Fahiminiya, S., Majewski, J., Faubert, D., Ostergaard, E., Smeitink, J., Shoubridge, E.A., Hinttala, R., Sasarman, F., Nishimura, T., Antonicka, H., Brunel-Guitton, C., Schwartzentruber, J., Fahiminiya, S., Majewski, J., Faubert, D., Ostergaard, E., Smeitink, J., and Shoubridge, E.A.
- Abstract
Contains fulltext : 153932.pdf (publisher's version ) (Closed access), Protein synthesis in mitochondria is initiated by formylmethionyl-tRNA(Met) (fMet-tRNA(Met)), which requires the activity of the enzyme MTFMT to formylate the methionyl group. We investigated the molecular consequences of mutations in MTFMT in patients with Leigh syndrome or cardiomyopathy. All patients studied were compound heterozygotes. Levels of MTFMT in patient fibroblasts were almost undetectable by immunoblot analysis, and BN-PAGE analysis showed a combined oxidative phosphorylation (OXPHOS) assembly defect involving complexes I, IV and V. The synthesis of only a subset of mitochondrial polypeptides (ND5, ND4, ND1, COXII) was decreased, whereas all others were translated at normal or even increased rates. Expression of the wild-type cDNA rescued the biochemical phenotype when MTFMT was expressed near control levels, but overexpression produced a dominant-negative phenotype, completely abrogating assembly of the OXPHOS complexes, suggesting that MTFMT activity must be tightly regulated. fMet-tRNA(Met) was almost undetectable in control cells and absent in patient cells by high-resolution northern blot analysis, but accumulated in cells overexpressing MTFMT. Newly synthesized COXI was under-represented in complex IV immunoprecipitates from patient fibroblasts, and two-dimensional BN-PAGE analysis of newly synthesized mitochondrial translation products showed an accumulation of free COXI. Quantitative mass spectrophotometry of an N-terminal COXI peptide showed that the ratio of formylated to unmodified N-termini in the assembled complex IV was approximately 350:1 in controls and 4:1 in patient cells. These results show that mitochondrial protein synthesis can occur with inefficient formylation of methionyl-tRNA(Met), but that assembly of complex IV is impaired if the COXI N-terminus is not formylated.
- Published
- 2015
42. De novo mutations in the motor domain of KIF1A cause cognitive impairment, spastic paraparesis, axonal neuropathy, and cerebellar atrophy
- Author
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Lee, J.R., Srour, M., Kim, D., Hamdan, F.F., Lim, S.H., Brunel-Guitton, C., Decarie, J.C., Rossignol, E., Mitchell, G.A., Schreiber, A., Moran, R., Haren, K. van, Richardson, R., Nicolai, J., Oberndorff, K.M., Wagner, J.D., Boycott, K.M., Rahikkala, E., Junna, N., Tyynismaa, H., Cuppen, I., Verbeek, N.E., Stumpel, C.T., Willemsen, M.A., Munnik, S.A. de, Rouleau, G.A., Kim, E., Kamsteeg, E.J., Kleefstra, T., Michaud, J.L., Lee, J.R., Srour, M., Kim, D., Hamdan, F.F., Lim, S.H., Brunel-Guitton, C., Decarie, J.C., Rossignol, E., Mitchell, G.A., Schreiber, A., Moran, R., Haren, K. van, Richardson, R., Nicolai, J., Oberndorff, K.M., Wagner, J.D., Boycott, K.M., Rahikkala, E., Junna, N., Tyynismaa, H., Cuppen, I., Verbeek, N.E., Stumpel, C.T., Willemsen, M.A., Munnik, S.A. de, Rouleau, G.A., Kim, E., Kamsteeg, E.J., Kleefstra, T., and Michaud, J.L.
- Abstract
Item does not contain fulltext, KIF1A is a neuron-specific motor protein that plays important roles in cargo transport along neurites. Recessive mutations in KIF1A were previously described in families with spastic paraparesis or sensory and autonomic neuropathy type-2. Here, we report 11 heterozygous de novo missense mutations (p.S58L, p.T99M, p.G102D, p.V144F, p.R167C, p.A202P, p.S215R, p.R216P, p.L249Q, p.E253K, and p.R316W) in KIF1A in 14 individuals, including two monozygotic twins. Two mutations (p.T99M and p.E253K) were recurrent, each being found in unrelated cases. All these de novo mutations are located in the motor domain (MD) of KIF1A. Structural modeling revealed that they alter conserved residues that are critical for the structure and function of the MD. Transfection studies suggested that at least five of these mutations affect the transport of the MD along axons. Individuals with de novo mutations in KIF1A display a phenotype characterized by cognitive impairment and variable presence of cerebellar atrophy, spastic paraparesis, optic nerve atrophy, peripheral neuropathy, and epilepsy. Our findings thus indicate that de novo missense mutations in the MD of KIF1A cause a phenotype that overlaps with, while being more severe, than that associated with recessive mutations in the same gene.
- Published
- 2015
43. LPIN1 deficiency with severe recurrent rhabdomyolysis and persistent elevation of creatine kinase levels due to chromosome 2 maternal isodisomy
- Author
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Meijer, I.A., primary, Sasarman, F., additional, Maftei, C., additional, Rossignol, E., additional, Vanasse, M., additional, Major, P., additional, Mitchell, G.A., additional, and Brunel-Guitton, C., additional
- Published
- 2015
- Full Text
- View/download PDF
44. Prélèvements multiorganes de type Maastricht III en médecine intensive–réanimation. Organisation et retour d’expérience paramédicale dans un service pilote: Donation after Circulatory Death (Maastricht III Category) ICU Organization and Nurses’ Feedback from a Single Ward
- Author
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Rouzeau, C., Lecomte, E., Cailleton, A., Cornuault, M., Boulinguiez, C., Labourot, P., Reignier, J., and Guitton, C.
- Abstract
Copyright of Reanimation is the property of Lavoisier and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2018
- Full Text
- View/download PDF
45. An N-terminal formyl methionine on COX 1 is required for the assembly of cytochrome c oxidase
- Author
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Hinttala, R., primary, Sasarman, F., additional, Nishimura, T., additional, Antonicka, H., additional, Brunel-Guitton, C., additional, Schwartzentruber, J., additional, Fahiminiya, S., additional, Majewski, J., additional, Faubert, D., additional, Ostergaard, E., additional, Smeitink, J. A., additional, and Shoubridge, E. A., additional
- Published
- 2015
- Full Text
- View/download PDF
46. Défaillance multiviscérale et infection disséminée à adénovirus
- Author
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Bretonnière, C., Touzeau, C., Guillaume, T., Coste-Burel, M., Moreau, A., Hamidou, M., Guitton, C., and Villers, D.
- Published
- 2010
- Full Text
- View/download PDF
47. SFP CO-01 - Efficacité du rituximab dans les anémies hémolytiques auto-immmunes (AHAI) pédiatriques
- Author
-
Ducassou, S., primary, Fernandes, H., additional, Leverger, G., additional, Bertrand, Y., additional, Chambost, H., additional, Nelken, B., additional, Guitton, C., additional, Plantaz, D., additional, Monpoux, F., additional, Lejars, O., additional, Aladjidi, N., additional, and Perel, Y., additional
- Published
- 2014
- Full Text
- View/download PDF
48. Life-threatening bacteremia and pyonephrosis caused by Enterococcus hirae
- Author
-
Brulé, N., primary, Corvec, S., additional, Villers, D., additional, Guitton, C., additional, and Bretonnière, C., additional
- Published
- 2013
- Full Text
- View/download PDF
49. Polymorphisme des molécules du CMH de classe I non classique : fréquence, distribution et impact des variants génétiques sur les fonctions endothéliales en transplantation
- Author
-
Gérard, N., primary, Tonnerre, P., additional, Gavlovsky, P.J., additional, Pabois, A., additional, Guitton, C., additional, Coupel, S., additional, and Charreau, B., additional
- Published
- 2013
- Full Text
- View/download PDF
50. Scanning electron microscopy of larval instars and imago of Rhinoestrus usbekistanicus Gan, 1947 (Oestridae)
- Author
-
Guitton, C., Dorchies, P., Serge Morand, ProdInra, Migration, Unité associée de Physiopathologie respiratoire des ruminants, and Institut National de la Recherche Agronomique (INRA)
- Subjects
[SDV] Life Sciences [q-bio] ,[SDV]Life Sciences [q-bio] - Published
- 1996
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