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1. Genomics-based timely detection of dengue virus type I genotypes I and V in Uruguay

Author

Morel, Noelia, Giovanetti, Marta, Fonseca, Vagner, Burgueño, Analía, Lima, Mauricio, Castro, Emerson, Guimarães, Natália R., Iani, Felipe C.M., Bormida, Victoria, Cortinas, Maria Noel, Ramas, Viviana, Coppola, Leticia, Bento, Ana I., Rosewell, Alexander, Franco, Leticia, Mendez Rico, Jairo, Lourenço, José, Junior Alcantara, Luiz Carlos, and Chiparelli, Hector

Published
2024
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2. Increased interregional virus exchange and nucleotide diversity outline the expansion of chikungunya virus in Brazil

Author

Xavier, Joilson, Alcantara, Luiz Carlos Junior, Fonseca, Vagner, Lima, Mauricio, Castro, Emerson, Fritsch, Hegger, Oliveira, Carla, Guimarães, Natalia, Adelino, Talita, Evaristo, Mariane, Rodrigues, Evandra S., Santos, Elaine Vieira, de La-Roque, Debora, de Moraes, Laise, Tosta, Stephane, Neto, Adelino, Rosewell, Alexander, Mendonça, Ana Flavia, Leite, Anderson, Vasconcelos, Andreza, Silva de Mello, Arabela L., Vasconcelos, Bergson, Montalbano, Camila A., Zanluca, Camila, Freitas, Carla, de Albuquerque, Carlos F. C., Duarte dos Santos, Claudia Nunes, Santos, Cleiton S., dos Santos, Cliomar Alves, Gonçalves, Crhistinne C. Maymone, Teixeira, Dalane, Neto, Daniel F. L., Cabral, Diego, de Oliveira, Elaine C., Noia Maciel, Ethel L., Pereira, Felicidade Mota, Iani, Felipe, de Carvalho, Fernanda P., Andrade, Gabriela, Bezerra, Gabriela, de Castro Lichs, Gislene G., Pereira, Glauco Carvalho, Barroso, Haline, Franz, Helena Cristina Ferreira, Ferreira, Hivylla, Gomes, Iago, Riediger, Irina N., Rodrigues, Isabela, de Siqueira, Isadora C., Silva, Jacilane, Rico, Jairo Mendez, Lima, Jaqueline, Abrantes, Jayra, do Nascimento, Jean Phellipe M., Wasserheit, Judith N., Pastor, Julia, de Magalhães, Jurandy J. F., Luz, Kleber Giovanni, Lima Neto, Lidio G., Frutuoso, Livia C. V., da Silva, Luana Barbosa, Sena, Ludmila, de Sousa, Luis Arthur F., Pereira, Luiz Augusto, Demarchi, Luiz, Câmara, Magaly C. B., Astete, Marcela G., Almiron, Maria, Lima, Maricelia, Umaki Zardin, Marina C. S., Presibella, Mayra M., Falcão, Melissa B., Gale, Jr., Michael, Freire, Naishe, Marques, Nelson, de Moura, Noely F. O., Almeida Da Silva, Pedro E., Rabinowitz, Peter, da Cunha, Rivaldo V., Trinta, Karen S., do Carmo Said, Rodrigo F., Kato, Rodrigo, Stabeli, Rodrigo, de Jesus, Ronaldo, Hans Santos, Roselene, Kashima, Simone, Slavov, Svetoslav N., Andrade, Tamires, Rocha, Themis, Carneiro, Thiago, Nardy, Vanessa, da Silva, Vinicius, Carvalho, Walterlene G., Van Voorhis, Wesley C., Araujo, Wildo N., de Filippis, Ana M. B., and Giovanetti, Marta

Published
2023
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3. Potential use of high-resolution melting analyses for SARS-CoV-2 genomic surveillance

Author

de Souza Andrade, Adriana, Freitas, Eduarda Fernandes, de Castro Barbosa, Emerson, Guimarães, Natália Rocha, de Melo Iani, Felipe Campos, da Costa, Alana Vitor Barbosa, Bernardes, André Felipe Leal, Adelino, Talita Emile Ribeiro, Ataide, Ana Caroline Zampiroli, Gregianini, Tatiana Schäffer, Nunes, Jônathas Dias, Stringari, Lorenzzo Lyrio, Riediger, Irina Nastassja, Fernandes, Sandra Bianchini, de Jesus, Ronaldo, Fonseca, Vagner, and Caldas, Sérgio

Published
2023
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4. High Frequencies of kdr Mutation and Chikungunya Infection in Aedes aegypti Population from Minas Gerais, Brazil

Author

Almeida-Souza, Pedro Augusto, primary, Oliveira, Cirilo Henrique de, additional, Brito, Luiz Paulo, additional, Teixeira, Thaynara de Jesus, additional, Celestino, Iago Alves, additional, Penha, Gabriele Barbosa, additional, dos Santos, Ronaldo Medeiros, additional, Mendes, Wexley Miranda, additional, Ribeiro, Bergmann Morais, additional, Campos, Fabrício Souza, additional, Roehe, Paulo Michel, additional, Guimarães, Natalia Rocha, additional, Iani, Felipe C. M., additional, Martins, Ademir Jesus, additional, and Abreu, Filipe Vieira Santos de, additional

Published
2024
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7. A Multiplex Nanopore Sequencing Approach for the Detection of Multiple Arboviral Species

Author

Xavier, Joilson, primary, Fonseca, Vagner, additional, Adelino, Talita, additional, Iani, Felipe C. M., additional, Pereira, Glauco C., additional, Duarte, Myrian M., additional, Lima, Mauricio, additional, Castro, Emerson, additional, Oliveira, Carla, additional, Fritsch, Hegger, additional, Guimarães, Natalia, additional, Lamounier, Ludmila O., additional, Barreto, Fernanda Khouri, additional, Braga de Oliveira, Camilo M. M., additional, Maymone Gonçalves, Crhistinne C., additional, Malta Lima, Danielle, additional, de Oliveira, Elaine C., additional, de Castro Lichs, Gislene G., additional, Gomes, Iago, additional, Mazaro, Janaina, additional, Rodrigues, Janete T. N., additional, Abrantes, Jayra, additional, Colares, Jeová K. B., additional, Luz, Kleber G., additional, Barbosa da Silva, Luana, additional, Demarchi, Luiz, additional, Câmara, Magaly C. B., additional, Umaki Zardin, Marina C. S., additional, Sabatini Mello Pinheiro, Rafaela, additional, Barbosa Souza, Rutilene, additional, Haddad, Simone K., additional, Figueiredo da Silva, Stephanni, additional, Slavov, Svetoslav N., additional, Rocha, Themis, additional, Morel, Noelia, additional, Chiparelli, Hector, additional, Burgueño, Analía, additional, Bórmida, Victoria, additional, Cortinas, María N., additional, Martín, Rosario S., additional, Pereira, Allan C., additional, dos Santos, Marcelo F., additional, André Júnior, Walter, additional, Mendez Rico, Jairo, additional, Franco, Leticia, additional, Rosewell, Alexander, additional, do Carmo Said, Rodrigo F., additional, de Albuquerque, Carlos F. C., additional, Noia Maciel, Ethel L., additional, Santini de Oliveira, Marília, additional, Venâncio da Cunha, Rivaldo, additional, Vinhal Frutuoso, Livia C., additional, de Filippis, Ana M. B., additional, Giovanetti, Marta, additional, and Carlos Junior Alcantara, Luiz, additional

Published
2023
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8. A Multiplex Nanopore Sequencing Approach for the Detection of Multiple Arboviral Species.

Author

Xavier, Joilson, Fonseca, Vagner, Adelino, Talita, Iani, Felipe C. M., Pereira, Glauco C., Duarte, Myrian M., Lima, Mauricio, Castro, Emerson, Oliveira, Carla, Fritsch, Hegger, Guimarães, Natalia, Lamounier, Ludmila O., Barreto, Fernanda Khouri, Braga de Oliveira, Camilo M. M., Maymone Gonçalves, Crhistinne C., Malta Lima, Danielle, de Oliveira, Elaine C., de Castro Lichs, Gislene G., Gomes, Iago, and Mazaro, Janaina

Subjects
ARBOVIRUSES, REVERSE transcriptase polymerase chain reaction, CHIKUNGUNYA virus, YELLOW fever, POLYMERASE chain reaction
Abstract

The emergence and continued geographic expansion of arboviruses and the growing number of infected people have highlighted the need to develop and improve multiplex methods for rapid and specific detection of pathogens. Sequencing technologies are promising tools that can help in the laboratory diagnosis of conditions that share common symptoms, such as pathologies caused by emerging arboviruses. In this study, we integrated nanopore sequencing and the advantages of reverse transcription polymerase chain reaction (RT-PCR) to develop a multiplex RT-PCR protocol for the detection of Chikungunya virus (CHIKV) and several orthoflaviviruses (such as dengue (Orthoflavivirus dengue), Zika (Orthoflavivirus zikaense), yellow fever (Orthoflavivirus flavi), and West Nile (Orthoflavivirus nilense) viruses) in a single reaction, which provides data for sequence-based differentiation of arbovirus lineages. [ABSTRACT FROM AUTHOR]

Published
2024
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9. Increased interregional virus exchange and nucleotide diversity outline the expansion of the chikungunya virus ECSA lineage in Brazil

Author

Xavier, Joilson, primary, Alcantara, Luiz, additional, Fonseca, Vagner, additional, Lima, Mauricio, additional, Castro, Emerson, additional, Fritsch, Hegger, additional, Oliveira, Carla, additional, Guimarães, Natalia, additional, Adelino, Talita, additional, Evaristo, Mariane, additional, Rodrigues, Evandra S., additional, Santos, Elaine Vieira, additional, de La-Roque, Debora, additional, de Moraes, Laise, additional, Tosta, Stephane, additional, Neto, Adelino, additional, Rosewell, Alexander, additional, Mendonça, Ana Flavia, additional, Leite, Anderson, additional, Vasconcelos, Andreza, additional, Silva de Mello, Arabela L., additional, Vasconcelos, Bergson, additional, Montalbano, Camila A., additional, Zanluca, Camila, additional, Freitas, Carla, additional, de Albuquerque, Carlos F. C., additional, Duarte dos Santos, Claudia Nunes, additional, Santos, Cleiton S., additional, Alves dos Santos, Cliomar, additional, Maymone Gonçalves, Crhistinne C., additional, Teixeira, Dalane, additional, Neto, Daniel F. L., additional, Cabral, Diego, additional, de Oliveira, Elaine C., additional, Noia Maciel, Ethel L., additional, Pereira, Felicidade Mota, additional, Iani, Felipe, additional, de Carvalho, Fernanda P., additional, Andrade, Gabriela, additional, Bezerra, Gabriela, additional, de Castro Lichs, Gislene G., additional, Pereira, Glauco Carvalho, additional, Barroso, Haline, additional, Ferreira Franz, Helena Cristina, additional, Ferreira, Hivylla, additional, Gomes, Iago, additional, Riediger, Irina N., additional, Rodrigues, Isabela, additional, de Siqueira, Isadora C., additional, Silva, Jacilane, additional, Rico, Jairo Mendez, additional, Lima, Jaqueline, additional, Abrantes, Jayra, additional, do Nascimento, Jean Phellipe M., additional, Wasserheit, Judith N., additional, Pastor, Julia, additional, de Magalhães, Jurandy J. F., additional, Luz, Kleber Giovanni, additional, Lima Neto, Lidio G., additional, Frutuoso, Livia C. V., additional, da Silva, Luana Barbosa, additional, Sena, Ludmila, additional, de Sousa, Luis Arthur F., additional, Pereira, Luiz Augusto, additional, Demarchi, Luiz, additional, Câmara, Magaly C. B., additional, Astete, Marcela G., additional, Almiron, Maria, additional, Lima, Maricelia, additional, Umaki Zardin, Marina C. S., additional, Presibella, Mayra M., additional, Falcão, Melissa B., additional, Gale, Michael, additional, Freire, Naishe, additional, Marques, Nelson, additional, de Moura, Noely F. O., additional, Almeida Da Silva, Pedro E., additional, Rabinowitz, Peter, additional, da Cunha, Rivaldo V., additional, Trinta, Karen S., additional, do Carmo Said, Rodrigo F., additional, Kato, Rodrigo, additional, Stabeli, Rodrigo, additional, de Jesus, Ronaldo, additional, Santos, Roselene Hans, additional, Haddad, Simone K., additional, Slavov, Svetoslav N., additional, Andrade, Tamires, additional, Rocha, Themis, additional, Carneiro, Thiago, additional, Nardy, Vanessa, additional, da Silva, Vinicius, additional, Carvalho, Walterlene G., additional, Van Voorhis, Wesley C., additional, Araujo, Wildo N., additional, de Filippis, Ana M.B., additional, and Giovanetti, Marta, additional

Published
2023
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11. Rosemary (Rosmarinus officinalis L.) Glycolic Extract Protects Liver Mitochondria from Oxidative Damage and Prevents Acetaminophen-Induced Hepatotoxicity

Author

Guimarães, Natalia S. S., primary, Ramos, Vyctória S., additional, Prado-Souza, Laura F. L., additional, Lopes, Rayssa M., additional, Arini, Gabriel S., additional, Feitosa, Luís G. P., additional, Silva, Ricardo R., additional, Nantes, Iseli L., additional, Damasceno, Debora C., additional, Lopes, Norberto P., additional, and Rodrigues, Tiago, additional

Published
2023
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12. Saúde da Mulher vol.2

Author

Prudente, Ana Carolina Ferreira, primary, Souza, Caroline Pina Ribeiro de, additional, Evangelista, Hilary Hevellin, additional, Araújo, Isabella Correia Teodoro de, additional, Albiero, Lívia Grandini, additional, Naves, Maria Eduarda Curado, additional, Py, Renata Bueno Bucci, additional, Evangelista, Thaynara Hevellin, additional, Goulart, Tiago Dornelas, additional, Manso, Vitória Abdala, additional, Silva, Izabelle Barreto, additional, Carvalho, Maria Carolina Pereira de, additional, Bacha, Karimi Mohamed El, additional, VAZ, SÍLVIO HENRIQUE DA SILVA, additional, SOUSA, VINÍCIUS LÚCIO DE, additional, Bolestero, Nayara Borges, additional, Cavalcante, Manuelly Benayon, additional, SANTOS, TALITA MIRANDA, additional, Antonio, Letícia Tosta, additional, REZENDE, LARISSA CAROLINE, additional, Bottcher, Matheus Gilberti, additional, Batista, João Victor Falcão, additional, Queiroz, Marcel Reis de, additional, Morais, Marco Antônio Rodrigues de, additional, Batista, Athus Wanileres de Carvalho, additional, Souza, Clara Fortes Machado, additional, Costa, Lygia Marina Mendes da, additional, Costa, Gabrielle Peres da, additional, Silva, Marina Christine Rio Branco da, additional, Santos, Pamella Dalabeneta Fernandes, additional, Meirelles, Rayane dos Santos, additional, Viniegra, Rocio Fernandez Santos, additional, Florentino, Emmanuelle Batista, additional, Esteves, Mônica Del Monaco, additional, Machado, Rafael Augusto Chaves, additional, Castro, Tuani de Oliveira, additional, Mello, Victor Mendel da Silva, additional, Cavalcanti, Silvia Maria Baeta, additional, Maia, Larissa Gontijo Silva, additional, ALVES, CAMILA SOUSA BRAGUNCE, additional, Lopes, Maria Clara Lucio, additional, Gonçalves, Laryssa Vieira, additional, Jardim, Valeria Cristina, additional, Andrade, Rafael Almerindo Bicalho Silveira, additional, Rosa, Laura Miranda, additional, Custódio, Ana Beatriz Guimarães, additional, Góis, Luiza Antunes, additional, Oliveira, Marcella Lima, additional, Costa, Carolina Gomes da, additional, Monteiro, Yolanda Talissa, additional, Silva, Natália Corrêa da, additional, Ruggio, Polyana Fernandes, additional, Mata, Lívia Fernandes Monteiro da, additional, Reis, Priscilla de Oliveira, additional, Machado, Tamyres Karen Fagundes, additional, França, Mateus Coelho, additional, Santoliquido, Karina Rumi De Moura, additional, Gabioli, Lorena Silvestre, additional, Ferreira, Isabela Munhoz, additional, Diana, Mariana Bighetti, additional, Gonçalves, Aylla Corrêa, additional, Sá, Maria Eduarda de, additional, Montandon, Beatriz Soares, additional, Sabino, Poliana Botelho, additional, Souza, Larissa de, additional, Oliveira, Josequeli Maria Goulart, additional, Rodrigues, Maria Luiza Monteiro, additional, Souza, Nara Batista de, additional, Nascimento, Nathália Helena Bertolin do, additional, Vilete, Maria Clara Adario, additional, Pascini, Igor Pena, additional, Diniz, Hugo Zaghetto, additional, Freire, Nathália de Souza Abreu, additional, Cordeiro, Gisele Fernandes Tama, additional, Santos, Bruna Luísa Fischer, additional, Silva, Cecília Andrade, additional, Silva, Deise da, additional, Silva, Diego Ferreira, additional, Oliveira, Gabriela de, additional, Gomes, Gabriela Somma, additional, Tsubono, Gabriela Yumi, additional, Eiri, Karina Akemi, additional, Silva, Nathália Andrade, additional, Silva, Luciana Canela de Siqueira, additional, Tavares, Dayana Marques, additional, Bellis, Anna Luisa Vieira, additional, Matos, Carolina Cunha, additional, Ferreira, Fernanda Damasceno, additional, Souza Neto, Igor de, additional, Borges, Ludmila Souza Recedive, additional, Bottaro, Victória Barros, additional, Santos, Arthur Barbosa, additional, Amaral, Mariana de Souza, additional, SILVA, Rita de Cássia, additional, Paula, Luanna Marques de, additional, Couto, Fernanda Machado, additional, Domiciano, Leticia Santana, additional, Peixoto, Maria Clara Almeida, additional, BASTOS, MARIANA RODRIGUES MARINHO DE, additional, Ribeiro, Flávia Coutinho Loureiro, additional, Tameirão, Daniela Cristina Machado, additional, Pinheiro, Ana Maria Pearce de Area Leão, additional, Barili, Isabela Ceccato, additional, Arsmtrong, Bruna Benigna Sales, additional, Silva, Idna Karime de Sousa, additional, Moreira, Kassio Costa, additional, Bezerra, Mateus Soares, additional, Ribeiro, Bianca Leal, additional, Granja, Flanymagna Costa Nunes, additional, Neta, Francisca Castro Fontinele, additional, Holanda, Ana Maria Coelho, additional, Carvalho, Enio Douglas Amorim, additional, Oliveira, Ana Julia Pereira de, additional, Barbosa, Gabriel Moreno, additional, Gerônimo, Iara Paiva, additional, Silva, João Inácio Migliorini, additional, Godoy, Júlia Ribeiro Dias, additional, Carmo, Lara Pereira do, additional, Almeida, Lívia Maria Rodrigues de, additional, GODOY, LUÍSA RIBEIRO DIAS, additional, Barboza, Maria Luiza Rosa, additional, Romero, Matheus Alberto Dias, additional, PENHA, PAULA VIEIRA, additional, SPENAZATO JÚNIOR, VALDECIR BOENO, additional, Carvalho, Elisa Moraes, additional, Rodrigues, Gustavo Galarza, additional, Salgado, Larissa Januário, additional, Santos, Mariana Fernandes Moreira dos, additional, Ferreira, Matheus Augusto, additional, Pinheiro, Rafaela Pereira, additional, Pierot, Esteffany Vaz, additional, Lacerda Neto, Jurandir carvalho de, additional, Lima, Heloisa Rolin Marques, additional, Moura, Alexandre de Sousa, additional, Morais, Wellington Sousa, additional, Barbosa, Alexandre de Sousa, additional, Sousa, Camila França da Silveira e, additional, Gois, Gedivan Pereira de, additional, Ferreira, Daniel Henrique da Silva, additional, Medeiros, Beatriz Silva Freitas de, additional, Fonseca, Davila Fernanda Rodrigues, additional, Ibiapina, Aline Raquel de Sousa, additional, Gomes, Wilklânia Laíse Lima, additional, Oliveira, Camila Barbosa Sousa, additional, Carvalho, Tayline Guedes de Miranda, additional, Primo, Maísa Guimarães Silva, additional, MARTINS, MARIA DO CARMO DE CARVALHO E, additional, Assis, Leonardo de Oliveira, additional, Souza, Danielli Carolina Brito, additional, Melo, Paula Stephanie Meneses, additional, Lucchesi, Carolina Basilio, additional, Carvalho, Rayssa Mirelle Santos, additional, Militão, Mônica Pimentel Lima, additional, Carozo, Isadora Vieira, additional, Sobral, Marina Prado Santos, additional, Morais, Vanessa Maria Oliveira, additional, Feijó, Walter Aguiar, additional, Carvalho, Maria Eugênia Ruas, additional, Carvalho, Giulia Morais Leandro de, additional, Paula, Geovana Oliveira de, additional, Rocha, Taís Garcia, additional, Peleja, Jaqueline de Pádua, additional, Paula, Isadora Garcia de, additional, Porto, André Quintino, additional, Melo Neto, Alaor Cabral de, additional, Oliveira, Ana Beatriz Campos de, additional, Faria, Beatriz Saad Sabino de Campos, additional, Morelli, Luciana Caldeira, additional, Coutinho, Fernanda Silva, additional, Paschoali, Anderson Luís, additional, Avi, Fernando Ribeiro de Oliveira, additional, Gonsales, Gabriela Melo, additional, Matos, Mateus dos Santos Rios, additional, Chagas, Polyanne Almeida Santos, additional, Constantino, Eduardo, additional, Lopes, Leandro Paranhos, additional, Silva, Leda Maria Ferraz da, additional, Sonehara, Nathália Martins, additional, Pereira, Felipe Augusto de Oliveira, additional, Alves, Adriana Corrêa, additional, Andrade, Ana Flávia Faria, additional, Silva, Ana Luiza Carvalho, additional, Lima, Bruna Cecília Almeida, additional, Lima, Brunna Cecília Almeida, additional, Couri, Ingridh Campelo, additional, Martins, Katharine Gonçalves, additional, Amorim, Maria Cecília Alencar de, additional, Oliveira, Beatriz de Santana de, additional, Hinojosa, Joanna Lidia Fernandes, additional, Coutinho, Gabriely Oliveira Fernandes, additional, Amaral, Ada Maria Myrna Nascimento do, additional, Mendonça, Laís Silva Bezerra de, additional, Vasconcelos, Barbara Monique de Freitas, additional, Vasconcelos, Thalyta Layze Paiva, additional, Gonçalves, João Vitor de Alencar Duarte, additional, Ferreira, Brunna Karolyne Aguiar, additional, Melo, Gabriela Madeira de, additional, Leite, Lara Maria Carvalho, additional, Barbosa, Fernanda Resende Buldrini, additional, Campolina, Gabriela Arbex, additional, Elias, Gabriela Couto, additional, Mendes, Evelyn Botrel, additional, Sousa, Taiany Flaviany Lucia de, additional, Leonardi, Fernando Augusto Horikawa, additional, Gonçalves, Tayná Vilela Lima, additional, Cavalari, Bruna Eduarda Costa, additional, Silva Junior, Marcelo Beneti da, additional, Gasparotto, Rafaela Duarte, additional, Pacheco, Lyvia do Prado, additional, Fortunato, Luiza de Oliveira, additional, Guimarães, Natalia Dier, additional, Regiani, Natalia Marin, additional, Reis, Paula Macedo, additional, Medeiros, Elisa Smith Barbiero, additional, Drumond, Loise Cristina Passos, additional, Paulo, Marcela Souza Lima, additional, Furbringer, Ariane, additional, Baggio, Flavia Turmena, additional, Silveira, Emerson da, additional, Piva, Gabriela Dal, additional, Maes, Giulia Veronica Garcia, additional, Vinhaga, Júlia Casanova, additional, Pinto, Julia Massotti, additional, Baptista, Maria Júlia, additional, Benedet, Marina Corbetta, additional, Guimarães, Ilma Érika Gonçalos, additional, Faion, Isadora Stephan, additional, Niza, Vitória Freitas, additional, Braga, Barbara Nogueira, additional, Ferraz, Luisa, additional, Gonçalves, Karoline Carvalho Ramos, additional, Assunção, Lucas Camargo, additional, and Simonetti, Marcella Ricardo Silva, additional

Published
2021
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19. The Effects of Hypergravity and Radiation Exposure on Plants and their Terrestrial and Space Applications

Author

Araújo dos Santos, Marlise, A de Souza, Beatriz, Guimarães, Natalia, Escobal, Felipe C, Lazzarotto, Patrícia Bellicanta, Souvestre, Philippe A, and Russomano, Thais

Subjects
fungi, food and beverages
Abstract

Introduction: The Bellagio II Summit discussed several aspects related to space nutrition, space pharmacy and the influence of the space environment on plants and their compounds. Plant germination and growth are influenced by innumerous environmental factors, such as the level of gravity and type of radiation. Since several plants have nutritive and medicinal value, the importance of their cultivation and consumption during space missions are unquestionable. Studies have demonstrated that simulated hypergravity through centrifuge exposure increases the number of seed germination, accelerates plant growth and the modifies metabolitesproduced by some plants. The radiation of space, either in Low Earth Orbit or in deep space, can also positively impact on plant growth and metabolite production.Methods: The effects of different levels of gravitational fields and types of radiation on plant germination and development were reviewed for application in space missions and food and pharmaceutical industries on Earth.Results: Faster germination and increased growth of Rocket plant seeds, as well as higher rates of germination of carrot seeds were observed when subjected to intermittent exposure at +7Gz. The scientific literature shows that using UV-C radiation (non-ionizing radiation) on arugula increased its production of antioxidant and polyphenols compounds, and shortened strawberry maturation by 4 to 8 days, without affecting the average weight of the fruit. Gamma (ionizing) radiation, however, reduced the average height of fava beans, but did not affect germination. It can also be used to disinfect vegetables.Discussion: This paper reviewed the literature related to the effects of hypergravity conditions, as well as different types of radiation exposure on the plant life cycle and production of their compounds. The findings reviewed suggest that several plants present faster rates of germination and growth under hypergravity conditions. This may motivate the cultivation of such plants and vegetables using this method, not only on Earth, but also in more extreme environments, such as those found on space stations and extra-terrestrial bases. Studies conducted worldwide have demonstrated the potential advantages of applying radiation onplants. Hypergravity and radiation exposure, therefore, might be useful for terrestrial applications, especially in food production and medication development.

Published
2018

22. Partial proteomic characterization of the Phyllomedusa megacephala secretion and the differential activity of some peptides against tumor and non-tumor cell lines

Author

Avelar Júnior, Joaquim Teixeira, De Souza, Açucena, Ribeiro, Juliana Martins, Espanha, Juan, Guimarães, Natália Rocha, Belghazi, Maya, de Castro Pimenta, Adriano Monteiro, Eterovick, Paula, Resende, Jarbas Magalhães, Borges, Márcia Helena, Farias, Luiz M., Magalhães, Paula P., Martin-Eauclaire, Marie-France, Bougis, Pierre Edouard, Souza-Fagundes, Elaine Maria, and De Lima, Maria Elena

Published
2020
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26. Kocher-Debré-Sémélaigne syndrome diagnosed by autopsy associated with disseminated intravascular coagulation

Author

Guimarães, Natália Dias B., Espindula, Ana Paula, Rocha, Laura Penna, Olegário, Janaínna Grazielle Pacheco, Abate, Débora Tavares Resende Silva, e Silva, Renata Calciolari Rossi, Cavellani, Camila Lourencini, dos Reis, Marlene Antônia, Teixeira, Vicente de Paula Antunes, da Cunha Castro, Eumenia Costa, and Corrêa, Rosana Rosa Miranda

Published
2012
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28. Increased interregional virus exchange and nucleotide diversity outline the expansion of the chikungunya virus ECSA lineage in Brazil.

Author

Xavier J, Alcantara L, Fonseca V, Lima M, Castro E, Fritsch H, Oliveira C, Guimarães N, Adelino T, Evaristo M, Rodrigues ES, Santos EV, de La-Roque D, de Moraes L, Tosta S, Neto A, Rosewell A, Mendonça AF, Leite A, Vasconcelos A, Silva de Mello AL, Vasconcelos B, Montalbano CA, Zanluca C, Freitas C, de Albuquerque CFC, Duarte Dos Santos CN, Santos CS, Dos Santos CA, Maymone Gonçalves CC, Teixeira D, Neto DFL, Cabral D, de Oliveira EC, Noia Maciel EL, Pereira FM, Iani F, de Carvalho FP, Andrade G, Bezerra G, de Castro Lichs GG, Pereira GC, Barroso H, Ferreira Franz HC, Ferreira H, Gomes I, Riediger IN, Rodrigues I, de Siqueira IC, Silva J, Rico JM, Lima J, Abrantes J, do Nascimento JPM, Wasserheit JN, Pastor J, de Magalhães JJF, Luz KG, Lima Neto LG, Frutuoso LCV, da Silva LB, Sena L, de Sousa LAF, Pereira LA, Demarchi L, Câmara MCB, Astete MG, Almiron M, Lima M, Umaki Zardin MCS, Presibella MM, Falcão MB, Gale M Jr, Freire N, Marques N, de Moura NFO, Almeida Da Silva PE, Rabinowitz P, da Cunha RV, Trinta KS, do Carmo Said RF, Kato R, Stabeli R, de Jesus R, Santos RH, Haddad SK, Slavov SN, Andrade T, Rocha T, Carneiro T, Nardy V, da Silva V, Carvalho WG, Van Voorhis WC, Araujo WN, de Filippis AMB, and Giovanetti M

Abstract

The emergence and reemergence of mosquito-borne diseases in Brazil such as Yellow Fever, Zika, Chikungunya, and Dengue have had serious impacts on public health. Concerns have been raised due to the rapid dissemination of the chikungunya virus (CHIKV) across the country since its first detection in 2014 in Northeast Brazil. Faced with this scenario, on-site training activities in genomic surveillance carried out in partnership with the National Network of Public Health Laboratories have led to the generation of 422 CHIKV genomes from 12 Brazilian states over the past two years (2021-2022), a period that has seen more than 312 thousand chikungunya fever cases reported in the country. These new genomes increased the amount of available data and allowed a more comprehensive characterization of the dispersion dynamics of the CHIKV East-Central-South-African (ECSA) lineage in Brazil. Tree branching patterns revealed the emergence and expansion of two distinct subclades. Phylogeographic analysis indicated that the northeast region has been the leading hub of virus spread towards other regions. Increased frequency of C>T transitions among the new genomes suggested that host restriction factors from the immune system such as ADAR and AID/APOBEC deaminases might be driving CHIKV ECSA lineage genetic diversity in Brazil.

Published
2023
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