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3. Inflammation and vitamin D

Author

Guillot, X., Prati, C., Wendling, D., Saidenberg-Kermanac’h, N., Semerano, L., Falgarone, G., Boissier, M. C., and Watson, Ronald Ross, editor

Published
2013
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5. Additional file 1 of Effects of local cryotherapy on systemic endothelial activation, dysfunction, and vascular inflammation in adjuvant-induced arthritis (AIA) rats

Author

Peyronnel, C., Totoson, P., Petitcolin, V., Bonnefoy, F., Guillot, X., Saas, P., Verhoeven, F., Martin, H., and Demougeot, C.

Abstract

Additional file 1: Supplementary Figure 1. Gating strategies used to analyze leucocyte subsets in aorta and blood samples. (A-F) A representative analysis of total leucocytes, granulocytes, monocyte/macrophages, total T cells, CD4+ and CD8+ T cells in aorta is shown. Cells were first identified based on their size and granularity (A, FSC versus SSC) and then total leucocytes were identified on the expression of the pan-leucocyte marker, CD45 (B). Then, viable CD45+ cells were selected using the Fixable Viability Dye eFluor 780 (FvD) (C). In these viable CD45+ cells, monocytes/macrophages and neutrophils were distinguished based on the expression of CD11b/c and granulocytes (RP-1 antigen) (E). T cells were identified in viable CD45+ cells by the expression of CD3 (D). In these viable CD3+ T cells, CD4+ and CD8+ T cells were distinguished based on the expression of CD4 and CD8, respectively (F). (G-J) A representative analysis of IL-17-producing T cells in aorta is shown. Cells were first identified based on their size and granularity (FSC versus SSC), their viability (FvD low) and the expression of CD45. Then, Th17 cells were identified by the expression of CD3 and CD4 (G) and intracellular expression of IL-17A (H), while Tc17 were identified by the expression of CD3 and CD8 (I) and intracellular expression of IL-17A (J). (K-R) A representative analysis of circulating total leucocytes, myeloid cells, total T cells, CD4+ and CD8+ T cells is shown. Cells were first identified based on their size and granularity (K, FSC versus SSC). This gate allows us to identify microbeads that were quantified in L. Total leucocytes were identified on the expression of the pan-leucocyte marker, CD45 (M). In these CD45+ cells, myeloid cells (monocytes/macrophages and neutrophils) were distinguished based on the expression of CD11b/c expression (O). T cells were identified in CD45+ cells by the expression of CD3 (N). In these CD3+ T cells, CD4+ and CD8+ T cells were distinguished based on the expression of CD4 and CD8, respectively (P). (Q-R) A representative analysis of circulating IL-17-producing T cells is shown. Cells were first identified based on their size and granularity (FSC versus SSC), their viability (FvD low) and the expression of CD45. In these viable CD3+ T cells, CD4+ and CD8+ T cells were distinguished based on the expression of CD4 and CD8, respectively. Then, Tc17 were identified by the expression of CD8 and intracellular expression of IL-17A (Q), while Th17 cells were identified by the expression of CD4 and intracellular expression of IL-17A (R).

Published
2022
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20. Energy transition and territorial development: Potential to be questionned

Author

Banos, Vincent, Dehez, Jeoffrey, Guillot, X., Versteegh, P., Irstea Publications, Migration, Environnement, territoires et infrastructures (UR ETBX), and Institut national de recherche en sciences et technologies pour l'environnement et l'agriculture (IRSTEA)

Subjects
[SDE] Environmental Sciences, AQUITAINE, [SDE]Environmental Sciences, TRANSITION ÉNERGÉTIQUE
Abstract

National audience; Cette recherche questionne les promesses et les ambiguïtés de la transition énergétique en s'intéressant aux modalités de déploiement des projets bois-énergie en Aquitaine. Quelles sont les synergies et les valeurs qui sous-tendent leur émergence et leur ancrage aux territoires ? L'enquête menée souligne le poids des héritages territoriaux dans la diversité des « communautés de valeurs » construites, de la défense d'un tissu industriel à la réhabilitation d'un service public de l'énergie. Elle montre aussi que l'approvisionnement local est un levier important mais pas forcément une nécessité, ni un gage de durabilité pour ces territoires. Elle souligne enfin l'inventivité déployée pour s'adapter aux attendus croissants concernant la performance économique et environnementale des équipements installés. Cette réflexion invite in fine à mettre l'accent sur les enjeux de solidarité dans la production des communautés énergétiques durables et à développer des pratiques de planification adaptées à des sources d'énergie présentes partout mais en faible densité et de manière intermittente

Published
2019

21. Dactylite dans la spondyloarthrite récente : données de la cohorte DESIR

Author

Wendling, D., Prati, C., Saraux, A., Moltó, A., Pham, T., Dougados, M., Guillot, X., Service de Rhumatologie, Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon), Lymphocyte B et Auto-immunité (LBAI), Université de Brest (UBO)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Brestois Santé Agro Matière (IBSAM), Université de Brest (UBO), CHRU Brest - Service de Rhumatologie (CHU - BREST - Rhumato), Centre Hospitalier Régional Universitaire de Brest (CHRU Brest), Hôpital Cochin [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Hôpital de la Conception [CHU - APHM] (LA CONCEPTION), Service de rhumatologie [CHU Cochin], and Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Cochin [AP-HP]

Subjects
[SDV]Life Sciences [q-bio], ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2018

22. Dactylitis in Early Spondyloarthritis. Baseline Data from a Prospective French National Cohort

Author

Wendling, D., Prati, C., Saraux, A., Moltó, Anna, Pham, Thao, Dougados, Maxime, Guillot, X, Service de Rhumatologie [CHRU de Besançon], Centre Hospitalier Régional Universitaire [Besançon] (CHRU Besançon), Service de Rhumatologie, Centre Hospitalier Régional Universitaire [Besançon] (CHRU Besançon)-Hôpital Jean Minjoz, Lymphocyte B et Auto-immunité (LBAI), Université de Brest (UBO)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Brestois Santé Agro Matière (IBSAM), Université de Brest (UBO), CHRU Brest - Service de Rhumatologie (CHU - BREST - Rhumato), Centre Hospitalier Régional Universitaire de Brest (CHRU Brest), CHU Cochin [AP-HP], Service de rhumatologie [CHU Cochin], Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-CHU Cochin [AP-HP], Centre de Recherche Épidémiologie et Statistique Sorbonne Paris Cité (CRESS (U1153 / UMR_A_1125 / UMR_S_1153)), Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de la Recherche Agronomique (INRA)-Université Paris Descartes - Paris 5 (UPD5)-Université Sorbonne Paris Cité (USPC), Service de Rhumatologie [CHU Sainte Marguerite], Hôpital Sainte-Marguerite [CHU - APHM] (Hôpitaux Sud ), Fonctions et dysfonctions épithéliales - UFC (EA 4267) (FDE), Université de Franche-Comté (UFC), Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon), Hôpital Cochin [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Cochin [AP-HP], Université Paris Diderot - Paris 7 (UPD7)-Université Sorbonne Paris Cité (USPC)-Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de la Recherche Agronomique (INRA), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC), CHU Cochin [AP-HP]-Assistance publique - Hôpitaux de Paris (AP-HP) (APHP), and Institut National de la Recherche Agronomique (INRA)-Université Paris Diderot - Paris 7 (UPD7)-Université Paris Descartes - Paris 5 (UPD5)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM)

Subjects
[SDV]Life Sciences [q-bio], ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2018

30. Quête interdisciplinaire des identités de lieux sur le grand territoire autoroutier Gier-Ondaine. Laboratoire pour une théorie du projet intégré de paysage. Rapport final de recherche (2004-2008)

Author

Coste, Anne, Findeli, Alain, Guillot, X., Joliveau, Th., Keravel, S., Université de Nîmes (UNIMES), and Acquier, Françoise

Subjects
[SHS.ARCHI]Humanities and Social Sciences/Architecture, space management, [SHS.ARCHI] Humanities and Social Sciences/Architecture, space management
Abstract

+ CDROM ; Direction de l'architecture, Bureau de la recherche architecturale, urbaine et paysagère, Programme Art/Architecture/Paysage; no abstract

Published
2014

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